Search results for 'Biology, Experimental' (try it on Scholar)

460 found
Sort by:
  1. Marcel Weber (2005). Philosophy of Experimental Biology. Cambridge University Press.score: 204.0
    Exploring central philosophical issues concerning scientific research in modern experimental biology, this book clarifies the strategies, concepts, reasoning, approaches, tools, models and experimental systems deployed by researchers. It also integrates recent developments in historical scholarship, in particular, the New Experimentalism, making this work of interest to philosophers and historians of science as well as to biological researchers.
    Direct download  
     
    My bibliography  
     
    Export citation  
  2. Massimo Pigliucci (2013). The Nature of Evolutionary Biology: At the Borderlands Between Historical and Experimental Science. In Kostas Kampourakis (ed.), The Philosophy of Biology: A Companion for Educators. Springer.score: 186.0
    The scientific status of evolutionary theory seems to be more or less perennially under question. I am not referring here (just) to the silliness of young Earth creation- ism (Pigliucci 2002; Boudry and Braeckman 2010), or even of the barely more intel- lectually sophisticated so-called Intelligent Design theory (Recker 2010; Brigandt this volume), but rather to discussions among scientists and philosophers of science concerning the epistemic status of evolutionary theory (Sober 2010). As we shall see in what follows, this debate (...)
    Direct download  
     
    My bibliography  
     
    Export citation  
  3. Marcel Weber (forthcoming). Experimental Modeling in Biology: In Vivo Representation and Stand-Ins As Modeling Strategies. Philosophy of Science.score: 156.0
    Experimental modeling in biology involves the use of living organisms (not necessarily so-called "model organisms") in order to model or simulate biological processes. I argue here that experimental modeling is a bona fide form of scientific modeling that plays an epistemic role that is distinct from that of ordinary biological experiments. What distinguishes them from ordinary experiments is that they use what I call "in vivo representations" where one kind of causal process is used to stand in for (...)
    Direct download  
     
    My bibliography  
     
    Export citation  
  4. Ingo Brigandt (2006). Philosophical Issues in Experimental Biology. Biology and Philosophy 21 (3):423–435.score: 150.0
    Review essay of The Philosophy of Experimental Biology by Marcel Weber (Cambridge University Press, 2005).
    Direct download (10 more)  
     
    My bibliography  
     
    Export citation  
  5. Marcel Weber (2002). Incommensurability and Theory Comparison in Experimental Biology. Biology and Philosophy 17 (2):155-169.score: 150.0
    Incommensurability of scientific theories, as conceived by Thomas Kuhnand Paul Feyerabend, is thought to be a major or even insurmountable obstacletothe empirical comparison of these theories. I examine this problem in light ofaconcrete case from the history of experimental biology, namely the oxidativephosphorylation controversy in biochemistry (ca. 1961-1977). After a briefhistorical exposition, I show that the two main competing theories which werethe subject of the ox-phos controversy instantiate some of the characteristicfeatures of incommensurable theories, namely translation failure,non-corresponding predictions, and (...)
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  6. Vernon E. Scholes (1970). Cell Biology Experimental Cell Biology W. R. Bowen. Bioscience 20 (2):123-123.score: 150.0
    No categories
    Direct download (2 more)  
     
    My bibliography  
     
    Export citation  
  7. T. A. Hall (1994). Extremely Micro Analysis. X‐Ray Microanalysis In Biology: Experimental Techniques and Applications (;1993). Edited by D. C. SIGEE, A. J. MORGAN, A. T. SUMNER And A. WARLEY. Cambridge University Press, Cambridge. Xiv + 337 Pp. £50.00/$89.95. ISBN 0‐521‐41530‐6. [REVIEW] Bioessays 16 (2):150-150.score: 150.0
    Direct download (3 more)  
     
    My bibliography  
     
    Export citation  
  8. Bradley T. Scheer (1975). Marine Biology Experimental Marine Biology Richard N. Mariscal. Bioscience 25 (10):672-672.score: 150.0
    No categories
    Direct download (2 more)  
     
    My bibliography  
     
    Export citation  
  9. D. C. Sigee, A. J. Morgan, A. T. Sumner, A. Warley & T. A. Hall (1994). X-Ray Microanalysis in Biology: Experimental Techniques and Applications. Bioessays 16 (2):149.score: 150.0
     
    My bibliography  
     
    Export citation  
  10. Robert N. Brandon (1997). Does Biology Have Laws? The Experimental Evidence. Philosophy of Science 64 (4):457.score: 144.0
    In this paper I argue that we can best make sense of the practice of experimental evolutionary biology if we see it as investigating contingent, rather than lawlike, regularities. This understanding is contrasted with the experimental practice of certain areas of physics. However, this presents a problem for those who accept the Logical Positivist conception of law and its essential role in scientific explanation. I address this problem by arguing that the contingent regularities of evolutionary biology have a (...)
    Direct download (6 more)  
     
    My bibliography  
     
    Export citation  
  11. Hans-Jorg Rheinberger (1997). Experimental Complexity in Biology: Some Epistemological and Historical Remarks. Philosophy of Science 64 (4):254.score: 144.0
    My paper draws on examples from molecular biology, the details of which I have developed elsewhere (Rheinberger 1992, 1993, 1995, 1997). Here, I can give only a brief outline of my argument. Reduction of complexity is a prerequisite for experimental research. To make sense of the universe of living beings, the modern biologist is bound to divide his world into fragments in which parameters can be defined, quantities measured, qualities identified. Such is the nature of any "experimental system." (...)
    Direct download (5 more)  
     
    My bibliography  
     
    Export citation  
  12. Melinda Fagan, Experimental Standards: Evaluating Success in Stem Cell Biology.score: 144.0
    This paper aims to bring the epistemic dimensions of stem cell experiments out of the background, and show that they can be critically evaluated. After introducing some basic concepts of stem cell biology, I set out the current “gold standard” for experimental success in that field (§2). I then trace the origin of this standard to a 1988 controversy over blood stem cells (§3). Understanding the outcome of this controversy requires attention to the details of experimental techniques, the (...)
    No categories
    Translate to English
    | Direct download  
     
    My bibliography  
     
    Export citation  
  13. Jacob Stegenga (2009). Philosophy of Experimental Biology. Erkenntnis 71 (3):431-436.score: 144.0
    Philosophers have committed sins while studying science, it is said – philosophy of science focused on physics to the detriment of biology, reconstructed idealizations of scientific episodes rather than attending to historical details, and focused on theories and concepts to the detriment of experiments. Recent generations of philosophers of science have tried to atone for these sins, and by the 1980s the exculpation was in full swing. Marcel Weber’s Philosophy of Experimental Biology is a zenith mea culpa for philosophy (...)
    No categories
    Translate to English
    | Direct download  
     
    My bibliography  
     
    Export citation  
  14. J. D. Stemwedel (2007). Philosophy of Experimental Biology. Philosophical Review 116 (1):139-141.score: 144.0
    Review\n\n"This bookas lucid, comprehensive presentation will enlighten both\nstudents and academicians in philosophy, biology, and science history,\nas well as scientists in other disciplines, while stimulating further\ndiscussion and analytical treatments." CHOICE May 2005 \n\n\n"Weber's overall approach is compelling; his book's focus on philosophical\nsignificance to be found in details of experimental biology is a\nwelcome addition to the philosophy of biology and to the philosophy\nof science more generally." - Jonathan Kaplan, Oregon State University\n\n\nProduct Description\n\nExploring central philosophical issues concerning scientific research\nin modern experimental (...)
    No categories
    Direct download (6 more)  
     
    My bibliography  
     
    Export citation  
  15. Francisco Javier Serrano-Bosquet & Gustavo Caponi (2014). Warren Weaver and the Experimental Biology Program of the Rockefeller Foundation. Scientiae Studia 12 (1):137-167.score: 144.0
    El objetivo de este trabajo es poner al descubierto los principales valores cognitivos y epistemológicos desde los que Warren Weaver puso en marcha el Programa de Biología Experimental, un programa que llevado a cabo desde la presidencia de la división de ciencias naturales de la Fundación Rockefeller, marcó y condicionó en buena medida el posterior desarrollo de la investigación biológica. Para tal fin se mostrará, en primer lugar, cómo fue la llegada de Weaver a la Fundación Rockefeller, así como (...)
    No categories
    Translate to English
    | Direct download (2 more)  
     
    My bibliography  
     
    Export citation  
  16. Michel Morange (2012). From Experimental Systems to Evolutionary Biology: An Impossible Journey? History and Philosophy of the Life Sciences 35 (1):27-32.score: 132.0
    Direct download (2 more)  
     
    My bibliography  
     
    Export citation  
  17. C. J. Barnard (2011). Asking Questions in Biology: A Guide to Hypothesis Testing, Experimental Design and Presentation in Practical Work and Research Projects. Pearson.score: 132.0
  18. Karola Stotz (2009). Experimental Philosophy of Biology: Notes From the Field. Studies in History and Philosophy of Science Part A 40 (2):233-237.score: 126.0
    I use a recent 'experimental philosophy' study of the concept of the gene conducted by myself and collaborators to discuss the broader epistemological framework within which that research was conducted, and to reflect on the relationship between science, history and philosophy of science, and society.
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  19. Nils Roll-Hansen (1976). Critical Teleology: Immanuel Kant and Claude Bernard on the Limitations of Experimental Biology. Journal of the History of Biology 9 (1):59 - 91.score: 126.0
  20. Jason Scott Robert (2007). Philosophy of Experimental Biology (Review). Perspectives in Biology and Medicine 50 (1):158-160.score: 126.0
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  21. William A. Rottschaefer (2008). Biological and Physicochemical Explanations in Experimental Biology. Biological Theory 3 (4):380-390.score: 122.0
  22. Henning Schmidgen (2006). The Uncertainty of Philosophical Experiments. Rezension Von: Marcel Weber," The Philosophy of Experimental Biology", Cambrigde: Cambridge University Press, 2005. Biological Theory 1 (4):434-435.score: 122.0
    No categories
    Direct download  
     
    My bibliography  
     
    Export citation  
  23. Henning Schmidgen (2006). The Uncertainty of Philosophical Experiments: Philosophy of Experimental Biology Marcel Weber Cambridge : Cambridge University Press , 2005 (358 Pp; $75.00 Hbk; ISBN 0521829453). [REVIEW] Biological Theory 1 (4):434-435.score: 122.0
  24. N. Rashevsky (1938). The Relation of Mathematical Biophysics to Experimental Biology. Acta Biotheoretica 4 (2).score: 120.0
    Direct download  
     
    My bibliography  
     
    Export citation  
  25. G. Albrecht-Buehler (1976). Numerical Evaluation of the Validity of Experimental Proofs in Biology. Synthese 33 (1):283 - 312.score: 120.0
    This paper suggests a method to calculate a degree of validity for the proof of a statement which is derived from empirical statements by means of logic conclusions. The empirical statements are assumed not to be completely valid or their validity to be doubtful. The suggested rules are consistent with two-valued logic, yield decreasing validities with increasing number of applications of modus ponens and obey the law of the excluded middle. The actual calculation of validity values, the relation of the (...)
    No categories
    Direct download (5 more)  
     
    My bibliography  
     
    Export citation  
  26. Edward Manier (1969). The Experimental Method in Biology. Synthese 20 (2):185 - 205.score: 120.0
    No categories
    Direct download (5 more)  
     
    My bibliography  
     
    Export citation  
  27. Robert L. Perlman (2005). Review of Marcel Weber, Philosophy of Experimental Biology. [REVIEW] Notre Dame Philosophical Reviews 2005 (2).score: 120.0
    No categories
    Direct download  
     
    My bibliography  
     
    Export citation  
  28. Victor A. Chepurnov, David G. Mann, Peter von Dassow, Pieter Vanormelingen, Jeroen Gillard, Dirk Inzé, Koen Sabbe & Wim Vyverman (2008). In Search of New Tractable Diatoms for Experimental Biology. Bioessays 30 (7):692-702.score: 120.0
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  29. Anna Maria Gillis (1991). Research Update From the Atlanta, Georgia, Meeting of the Federation of American Societies for Experimental Biology. Bioscience 41 (8):535-538.score: 120.0
    No categories
    Direct download  
     
    My bibliography  
     
    Export citation  
  30. Jonathan Kaplan (2005). Marcel Weber, Philosophy of Experimental Biology Reviewed By. Philosophy in Review 25 (6):447-449.score: 120.0
    No categories
    Direct download  
     
    My bibliography  
     
    Export citation  
  31. Marcel Weber (2002). Theory Testing in Experimental Biology: The Chemiosmotic Mechanism of ATP Synthesis. Studies in History and Philosophy of Science Part C 33 (1):29-52.score: 120.0
    Direct download (3 more)  
     
    My bibliography  
     
    Export citation  
  32. Jacob Stegenga (2009). Marcel Weber: Philosophy of Experimental Biology. [REVIEW] Erkenntnis 71 (3):431-436.score: 120.0
    No categories
    Direct download (5 more)  
     
    My bibliography  
     
    Export citation  
  33. David Boersema (2006). Review of “Embryology, Epigenesis, and Evolution” and “Philosophy of Experimental Biology”. [REVIEW] Essays in Philosophy 7 (1):1.score: 120.0
    Direct download  
     
    My bibliography  
     
    Export citation  
  34. Julian F. Burke (1991). Sticky Technique.In Situ Hybridisation: Application to Developmental Biology and Medicine (1990). Edited by N. Harris and D. G. Wilkinson. Cambridge University Press: Society for Experimental Biology Seminar Series 40. 288pp. $59.50, �35. [REVIEW] Bioessays 13 (12):692-692.score: 120.0
  35. Francis Heylighen (1999). Paul S. Agutter Was Reader in Cell Biology at Napier University in Edinburgh, and His Main Experimental Interest is in the Transport of Molecules Between the Nuclear and the Cytoplasm. His Most Recent Book, The Meaning of Nucleocytoplasmic Transport, Co-Authored with Philip Taylor, Was Published in 1996 by RG Landes Company. [REVIEW] Foundations of Science 4:107-109.score: 120.0
    Direct download  
     
    My bibliography  
     
    Export citation  
  36. Nils Roll-Hansen (1979). Reductionism in Biological Research: Reflections on Some Historical Case Studies in Experimental Biology. In Jan Bärmark (ed.), Perspectives in Metascience. Kungl. Vetenskaps- Och Vitterhets-Samhället. 2--157.score: 120.0
    No categories
     
    My bibliography  
     
    Export citation  
  37. Shozo Yokoyama (2012). Synthesis of Experimental Molecular Biology and Evolutionary Biology: An Example From the World of Vision. Bioscience 62 (1):939.score: 120.0
    No categories
    Direct download  
     
    My bibliography  
     
    Export citation  
  38. Jérôme Pierrel (2012). An RNA Phage Lab: MS2 in Walter Fiers' Laboratory of Molecular Biology in Ghent, From Genetic Code to Gene and Genome, 1963-1976. [REVIEW] Journal of the History of Biology 45 (1):109 - 138.score: 108.0
    The importance of viruses as model organisms is well-established in molecular biology and Max Delbrück's phage group set standards in the DNA phage field. In this paper, I argue that RNA phages, discovered in the 1960s, were also instrumental in the making of molecular biology. As part of experimental systems, RNA phages stood for messenger RNA (mRNA), genes and genome. RNA was thought to mediate information transfers between DNA and proteins. Furthermore, RNA was more manageable at the bench than (...)
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  39. Liz Stillwaggon Swan (2009). Synthesizing Insight: Artificial Life as Thought Experimentation in Biology. Biology and Philosophy 24 (5):687-701.score: 90.0
    What is artificial life? Much has been said about this interesting collection of efforts to artificially simulate and synthesize lifelike behavior and processes, yet we are far from having a robust philosophical understanding of just what Alifers are doing and why it ought to interest philosophers of science, and philosophers of biology in particular. In this paper, I first provide three introductory examples from the particular subset of artificial life I focus on, known as ‘soft Alife’ (s-Alife), and follow up (...)
    Direct download (5 more)  
     
    My bibliography  
     
    Export citation  
  40. Michel Morange (2010). How Evolutionary Biology Presently Pervades Cell and Molecular Biology. Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 41 (1):113 - 120.score: 90.0
    The increasing place of evolutionary scenarios in functional biology is one of the major indicators of the present encounter between evolutionary biology and functional biology (such as physiology, biochemistry and molecular biology), the two branches of biology which remained separated throughout the twentieth century. Evolutionary scenarios were not absent from functional biology, but their places were limited, and they did not generate research programs. I compare two examples of these past scenarios with two present-day ones. At least three characteristics distinguish (...)
    Direct download (6 more)  
     
    My bibliography  
     
    Export citation  
  41. Mark B. Adams (2000). Last Judgment: The Visionary Biology of J. B. S. Haldane. [REVIEW] Journal of the History of Biology 33 (3):457 - 491.score: 90.0
    This paper seeks to reinterpret the life and work of J. B. S. Haldane by focusing on an illuminating but largely ignored essay he published in 1927, "The Last Judgment" -- the sequel to his better known work, "Daedalus" (1924). This astonishing essay expresses a vision of the human future over the next 40,000,000 years, one that revises and updates Wellsian futurism with the long range implications of the "new biology" for human destiny. That vision served as a kind of (...)
    Direct download (5 more)  
     
    My bibliography  
     
    Export citation  
  42. James Maxwell Little (1961). An Introduction to the Experimental Method. Minneapolis, Burgess Pub. Co..score: 90.0
    No categories
     
    My bibliography  
     
    Export citation  
  43. Jane Maienschein (1986). Arguments for Experimentation in Biology. PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association 1986:180 - 195.score: 84.0
    By 1900 most biologists accepted experimentation as appropriate for at least parts of biology. Some claimed experimentation as the best or only proper approach to biology, while others regarded it as an acceptable addition to existing methodologies. Different researchers defined experimentation in different ways, and they held different aspirations for their experimental programs. This paper explores three sets of ideas, represented respectively by the French in the 1870s, the Germans in the 1880s, and the Americans in the 1890s. It (...)
    No categories
    Direct download (2 more)  
     
    My bibliography  
     
    Export citation  
  44. Hannes Rusch & Ulrich J. Frey (2013). Biological and Experimental Perspectives on Self-Interest: Reciprocal Altruism and Genetic Egoism. In Christoph Luetge (ed.), Handbook of the Philosophical Foundations of Business Ethics. Springer. 313-335.score: 84.0
    The question on how the diverse forms of cooperative behavior in humans and nonhuman animals could have evolved under the pressure of natural selection has been a challenge for evolutionary biology ever since Darwin himself. In this chapter, we briefly review and summarize results from the last 50 years of research on human and nonhuman cooperativeness from a theoretical (biology) and an experimental perspective (experimental economics). The first section presents six concepts from theoretical biology able to explain a (...)
    Direct download (2 more)  
     
    My bibliography  
     
    Export citation  
  45. Alejandro Garcia-Rivera, Mark Graves & Carl Neumann (2009). Beauty in the Living World. Zygon 44 (2):243-263.score: 72.0
    Almost all admit that there is beauty in the natural world. Many suspect that such beauty is more than an adornment of nature. Few in our contemporary world suggest that this beauty is an empirical principle of the natural world itself and instead relegate beauty to the eye and mind of the beholder. Guided by theological and scientific insight, the authors propose that such exclusion is no longer tenable, at least in the data of modern biology and in our view (...)
    Direct download (5 more)  
     
    My bibliography  
     
    Export citation  
  46. Laurent Loison (2011). French Roots of French Neo-Lamarckisms, 1879-1985. Journal of the History of Biology 44 (4):713 - 744.score: 72.0
    This essay attempts to describe the neo-Lamarckian atmosphere that was dominant in French biology for more than a century. Firstly, we demonstrate that there were not one but at least two French neo-Lamarckian traditions. This implies, therefore, that it is possible to propose a clear definition of a (neo) Lamarckian conception, and by using it, to distinguish these two traditions. We will see that these two conceptions were not dominant at the same time. The first French neo-Lamarckism (1879-1931) was structured (...)
    Direct download (5 more)  
     
    My bibliography  
     
    Export citation  
  47. Steindór J. Erlingsson (2009). The Plymouth Laboratory and the Institutionalization of Experimental Zoology in Britain in the 1920s. Journal of the History of Biology 42 (1):151 - 183.score: 72.0
    The Plymouth Laboratory of the Marine Biological Association of the United Kingdom (1884) was founded in 1888. In addition to conducting morphological and other biological research, the founders of the laboratory aimed at promoting research in experimental zoology which will be used in this paper as a synonym for e. g. experimental embryology, comparative physiology or general physiology. This dream was not fully realized until 1920. The Great War and its immediate aftermath had a positive impact on the (...)
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  48. Darrell P. Rowbottom (2011). Approximations, Idealizations and 'Experiments' at the Physics-Biology Interface. Studies in History and Philosophy of Biological and Biomedical Sciences 42 (2):145-154.score: 68.0
    This paper, which is based on recent empirical research at the University of Leeds, the University of Edinburgh, and the University of Bristol, presents two difficulties which arise when condensed matter physicists interact with molecular biologists: (1) the former use models which appear to be too coarse-grained, approximate and/or idealized to serve a useful scientific purpose to the latter; and (2) the latter have a rather narrower view of what counts as an experiment, particularly when it comes to computer simulations, (...)
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  49. Christophe Malaterre (2013). Synthetic Biology and Synthetic Knowledge. Biological Theory (8):346–356.score: 68.0
    Probably the most distinctive feature of synthetic biology is its being “synthetic” in some sense or another. For some, synthesis plays a unique role in the production of knowledge that is most distinct from that played by analysis: it is claimed to deliver knowledge that would otherwise not be attained. In this contribution, my aim is to explore how synthetic biology delivers knowledge via synthesis, and to assess the extent to which this knowledge is distinctly synthetic. On the basis of (...)
    Direct download (6 more)  
     
    My bibliography  
     
    Export citation  
  50. Sabina Leonelli (2013). Classificatory Theory in Biology. Biological Theory 7 (4):338-345.score: 68.0
    Scientific classification has long been recognized as involving a specific style of reasoning and doing research, and as occasionally affecting the development of scientific theories. However, the role played by classificatory activities in generating theories has not been closely investigated within the philosophy of science. I argue that classificatory systems can themselves become a form of theory, which I call classificatory theory, when they come to formalize and express the scientific significance of the elements being classified. This is particularly evident (...)
    Direct download (3 more)  
     
    My bibliography  
     
    Export citation  
1 — 50 / 460