Search results for 'Biomedical Research ethics' (try it on Scholar)

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  1. Kiarash Aramesh (2014). A Brief History of Biomedical Research Ethics in Iran: Conflict of Paradigms. Developing World Bioethics 14 (2).score: 720.0
    During the past two decades, Iran has experienced a noteworthy growth in its biomedical research sector. At the same time, ethical concerns and debates resulting from this burgeoning enterprise has led to increasing attention paid to biomedical ethics. In Iran, Biomedical research ethics and research oversight passed through major periods during the past decades, separated by a paradigm shift. Period 1, starting from the early 1970s, is characterized by research paternalism and (...)
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  2. Christopher Tollefsen (2008). Biomedical Research and Beyond: Expanding the Ethics of Inquiry. Routledge.score: 702.0
    Biomedical Research and Beyond: Expanding the Ethics of Inquiry investigates the ethics of biomedical and scientific inquiry, including embryonic research, animal research, genetic enhancement, and fairness in research in the developing world. Core concerns of biomedical and scientific research ethics are then shown also to be key in humanistic areas of inquiry. Biomedical Research and Beyond concludes with a discussion of the virtues that all inquirers, scientific, medical, (...)
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  3. Merryn Ekberg (2012). Reassessing the Role of the Biomedical Research Ethics Committee. Journal of Academic Ethics 10 (4):335-352.score: 630.0
    The role of the Research Ethics Committee (REC) in the design, conduct and dissemination of scientific research is still evolving and many important questions remain unanswered. Hence, the aim of this paper is to address some of the uncertainty that exists around the role and responsibilities of RECs and to discuss some of the controversy that exists over the criteria that RECs should follow when evaluating a research proposal. The discussion is organised around five of the (...)
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  4. Barbara K. Redman (2014). Review of Measurement Instruments in Research Ethics in the Biomedical Sciences, 2008−2012. [REVIEW] Research Ethics 10 (3):141-150.score: 564.0
    There is an urgent need in biomedical science to understand whether regulations are being met, prerequisite to goals of subject protection and integrity in research practice. This article presents an update of a 2006 summary of measurement instruments in research ethics with psychometric information in the years 2008−2012. A review of 25 instruments identified seven used in the time period 2008−2012 and which had accumulated at least one study of its psychometric qualities beyond its developmental phase. (...)
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  5. Baruch A. Brody (1998). The Ethics of Biomedical Research: An International Perspective. Oxford University Press.score: 561.0
    A broad critical review of national policies on biomedical research - human, epidemiologic, clinical trials, genetic, reproductive, etc.
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  6. E. Lamas, M. Ferrer, A. Molina, R. Salinas, A. Hevia, A. Bota, D. Feinholz, M. Fuchs, R. Schramm, J. -C. Tealdi & S. Zorrilla (2010). A Comparative Analysis of Biomedical Research Ethics Regulation Systems in Europe and Latin America with Regard to the Protection of Human Subjects. Journal of Medical Ethics 36 (12):750-753.score: 546.0
    The European project European and Latin American Systems of Ethics Regulation of Biomedical Research Project (EULABOR) has carried out the first comparative analysis of ethics regulation systems for biomedical research in seven countries in Europe and Latin America, evaluating their roles in the protection of human subjects. We developed a conceptual and methodological framework defining ‘ethics regulation system for biomedical research’ as a set of actors, institutions, codes and laws involved in (...)
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  7. David Koepsell, Robert Arp, Jennifer Fostel & Barry Smith (2009). Creating a Controlled Vocabulary for the Ethics of Human Research: Towards a Biomedical Ethics Ontology. Journal of Empirical Research on Human Research Ethics 4 (1):43-58.score: 546.0
    Ontologies describe reality in specific domains in ways that can bridge various disciplines and languages. They allow easier access and integration of information that is collected by different groups. Ontologies are currently used in the biomedical sciences, geography, and law. A Biomedical Ethics Ontology would benefit members of ethics committees who deal with protocols and consent forms spanning numerous fields of inquiry. There already exists the Ontology for Biomedical Investigations (OBI); the proposed BMEO would interoperate (...)
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  8. Jane A. Smith & Kenneth M. Boyd (eds.) (1991). Lives in the Balance: The Ethics of Using Animals in Biomedical Research: The Report of a Working Party of the Institute of Medical Ethics. Oxford University Press.score: 489.0
    This book is the result of a three-year study undertaken by a multidisciplinary working party of the Institute of Medical Ethic (UK). The group was chaired by a moral theologian, and its members included biological and ethological scientists, toxicologists, physicians, veterinary surgeons, an expert in alternatives to animal use, officers of animal welfare organizations, a Home Office Inspector, philosophers, and a lawyer. Coming from these different backgrounds, and holding a diversity of moral views, the members produced the agreed report as (...)
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  9. Evelyne Decullier, Véronique Lhéritier & François Chapuis (2005). The Activity of French Research Ethics Committees and Characteristics of Biomedical Research Protocols Involving Humans: A Retrospective Cohort Study. [REVIEW] BMC Medical Ethics 6 (1):1-10.score: 486.0
    Background Clinical trials throughout the world must be evaluated by research ethics committees. No one has yet attempted to clearly quantify at the national level the activity of ethics committees and describe the characteristics of the protocols submitted. The objectives of this study were to describe 1) the workload and the activity of Research Ethics Committees in France, and 2) the characteristics of protocols approved on a nation-wide basis. Methods Retrospective cohort of 976 protocols approved (...)
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  10. Matthew Weed (2004). Ethics, Regulation, and Biomedical Research. Kennedy Institute of Ethics Journal 14 (4):361-368.score: 486.0
    : Controversy has surrounded the institutions that facilitate discussion and regulation of American biomedical research for years. Recent challenges to the legitimacy of the President's Council on Bioethics have been focused on stem cell research. These arguments represent an opportunity to reconsider the legislation under which stem cell research is regulated, as well as to consider preexisting bodies like the Recombinant DNA Advisory Committee and National Bioethics Advisory Commission. This paper proposes a Federal Life Sciences Policy (...)
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  11. Robert C. Jones & Ray Greek (2014). A Review of the Institute of Medicine's Analysis of Using Chimpanzees in Biomedical Research. [REVIEW] Science and Engineering Ethics 20 (2):481-504.score: 480.0
    We argue that the recommendations made by the Institute of Medicine’s 2011 report, Chimpanzees in Biomedical and Behavioral Research: Assessing the Necessity, are methodologically and ethically confused. We argue that a proper understanding of evolution and complexity theory in terms of the science and ethics of using chimpanzees in biomedical research would have had led the committee to recommend not merely limiting but eliminating the use of chimpanzees in biomedical research. Specifically, we argue (...)
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  12. J. -P. Rwabihama, C. Girre & A. -M. Duguet (2010). Ethics Committees for Biomedical Research in Some African Emerging Countries: Which Establishment for Which Independence? A Comparison with the USA and Canada. Journal of Medical Ethics 36 (4):243-249.score: 480.0
    Context The conduct of medical research led by Northern countries in developing countries raises ethical questions. The assessment of research protocols has to be twofold, with a first reading in the country of origin and a second one in the country where the research takes place. This reading should benefit from an independent local ethical review of protocols. Consequently, ethics committees for medical research are evolving in Africa. Objective To investigate the process of establishing (...) committees and their independence. Method Descriptive study of 25 African countries and two North American countries. Data were recorded by questionnaire and interviews. Two visits of ethics committee meetings were conducted on the ground: over a period of 3 months in Kigali (Rwanda) and 2 months in Washington DC (USA). Results 22 countries participated in this study, 20 from Africa and two from North America. The response rate was 80%. 75% of local African committees developed into national ethics committees. During the last 5 years, these national committees have grown on a structural level. The circumstances of creation and the general context of underdevelopment remain the major challenges in Africa. Their independence could not be ensured without continuous training and efficient funding mechanisms. Institutional ethics committees are well established in USA and in Canada, whereas ethics committees in North America are weakened by the institutional affiliation of their members. Conclusion The process of establishing ethics committees could affect their functioning and compromise their independence in some African countries and in North America. (shrink)
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  13. James V. Lavery (ed.) (2007). Ethical Issues in International Biomedical Research: A Casebook. Oxford University Press.score: 474.0
    No other volume has this scope. Students in bioethics, public and international health, and ethics will find this book particularly useful.
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  14. Robert J. Levine, Samuel Gorovitz & James Gallagher (eds.) (2000). Biomedical Research Ethics: Updating International Guidelines: A Consultation: Geneva, Switzerland, 15-17 March 2000. Cioms.score: 468.0
     
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  15. Susan Eastwood, Pamela Derish, Evangeline Leash & Stephen Ordway (1996). Ethical Issues in Biomedical Research: Perceptions and Practices of Postdoctoral Research Fellows Responding to a Survey. Science and Engineering Ethics 2 (1):89-114.score: 465.0
    We surveyed 1005 postdoctoral fellows by questionnaire about ethical matters related to biomedical research and publishing; 33% responded. About 18% of respondents said they had taken a course in research ethics, and about 31% said they had had a course that devoted some time to research ethics. A substantial majority stated willingness to grant other investigators, except competitors, access to their data before publication and to share research materials. Respondents’ opinions about contributions justifying (...)
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  16. Stevan Harnad (2007). Ethics of Open Access to Biomedical Research: Just a Special Case of Ethics of Open Access to Research. Philosophy, Ethics, and Humanities in Medicine 2 (1):31.score: 462.0
    The ethical case for Open Access (OA) (free online access) to research findings is especially salient when it is public health that is being compromised by needless access restrictions. But the ethical imperative for OA is far more general: It applies to all scientific and scholarly research findings published in peer-reviewed journals. And peer-to-peer access is far more important than direct public access. Most research is funded so as to be conducted and published, by researchers, in order (...)
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  17. Ana Smith Iltis (2002). Biomedical Research Ethics. Journal of Medicine and Philosophy 27 (5):515 – 522.score: 450.0
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  18. David Rodríguez-Arias & Christian Hervé (2005). A Review Of: “Timothy F. Murphy. 2004.Case Studies in Biomedical Research Ethics”. [REVIEW] American Journal of Bioethics 5 (2):64-66.score: 450.0
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  19. B. G. Haire (2013). Ethics of Medical Care and Clinical Research: A Qualitative Study of Principal Investigators in Biomedical HIV Prevention Research. Journal of Medical Ethics 39 (4):231-235.score: 450.0
    In clinical research there is a tension between the role of a doctor, who must serve the best interests of the patient, and the role of the researcher, who must produce knowledge that may not have any immediate benefits for the research participant. This tension is exacerbated in HIV research in low and middle income countries, which frequently uncovers comorbidities other than the condition under study. Some bioethicists argue that as the goals of medicine and those of (...)
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  20. David Rodríguez-Arias & Christian Hervé (2005). A Review Of:“Timothy F. Murphy. 2004. Case Studies in Biomedical Research Ethics” Cambridge, MA: The MIT Press. 368 Pp. $29.00, Paperback. [REVIEW] American Journal of Bioethics 5 (2):64-66.score: 450.0
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  21. Mary E. Sunderland & Rahul Uday Nayak (forthcoming). Reengineering Biomedical Translational Research with Engineering Ethics. Science and Engineering Ethics:1-13.score: 450.0
    It is widely accepted that translational research practitioners need to acquire special skills and knowledge that will enable them to anticipate, analyze, and manage a range of ethical issues. While there is a small but growing literature that addresses the ethics of translational research, there is a dearth of scholarship regarding how this might apply to engineers. In this paper we examine engineers as key translators and argue that they are well positioned to ask transformative ethical questions. (...)
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  22. Thomas H. Murray & Josephine Johnston (eds.) (2010). Trust and Integrity in Biomedical Research: The Case of Financial Conflicts of Interest. Johns Hopkins University Press.score: 447.0
    This volume assesses the ethical, quantitative, and qualitative questions posed by the current financing of biomedical research.
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  23. Michael E. Frisina (2006). Commentary: The Application of Medical Ethics in Biomedical Research. Cambridge Quarterly of Healthcare Ethics 15 (04):439-441.score: 444.0
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  24. P. Sedgwick (1994). Lives in the Balance: The Ethics of Using Animals in Biomedical Research. Journal of Medical Ethics 20 (1):58-59.score: 444.0
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  25. Gayle Cartland Langley Rn & Anthony Egan Sj (2012). The Ethics of Care in Biomedical Research Committees. Journal of Clinical Research and Bioethics 3 (1).score: 444.0
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  26. Fawaz Mzayek & David Resnik (2010). International Biomedical Research and Research Ethics Training in Developing Countries. Journal of Clinical Research and Bioethics 1 (1).score: 444.0
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  27. Janet Borgerson (forthcoming). Preparing Ethics for the Future: Addressing the Global Basic Structure in the Ethics of International Biomedical Research Involving Human Subjects. Journal of Philosophical Research.score: 444.0
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  28. A. M. Chakrabarty (2002). Ethics in Biomedical Research: Practical Considerations. American Journal of Bioethics 2 (4):53 – 54.score: 435.0
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  29. John McMillan (2009). Review of Christopher O. Tollefsen, Biomedical Research and Beyond: Expanding the Ethics of Inquiry. [REVIEW] Notre Dame Philosophical Reviews 2009 (1).score: 435.0
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  30. Jan Helge Solbakk (1991). Ethics Review Committees [in Biomedical Research] in the Nordic Countries: History, Organization, and Assignments. [REVIEW] HEC Forum 3 (4):215-220.score: 435.0
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  31. Pēteris Zilgalvis (2002). The Council of Europe's Instruments on Biomedical Research: How is Conflict of Interest Addressed? [REVIEW] Science and Engineering Ethics 8 (3):277-281.score: 435.0
    Conflict of interest is an issue that has been put in the spotlight by the commercial application of the new biomedical technologies. This paper presents the approach of the Council of Europe and the binding legal instruments to deal with this problem. The main focus is on the Convention on Human Rights and Biomedicine, and its draft additional Protocol on Biomedical Research.
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  32. M. Cho, H. T. Greely, D. Magnus & J. Maienschein (forthcoming). Developing a New Paradigm for Integrating Ethics and Biomedical Research: Proposal for a Benchside Consultation Program. American Society for Bioethics and Humanities/Canadian Bioethics Society Joint Meeting.score: 435.0
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  33. Susan Ellenberg, Thomas Fleming & David DeMets (2008). 2006), A16. Brody, Baruch A. The Ethics of Biomedical Research: An International Perspective. New York: Oxford University Press, 1998. Capron, Alexander M." Experimentation with Human Beings: Light or Only Shadows?" Yale Journal of Health Policy, Law And. [REVIEW] Contemporary Issues in Bioethics 15 (1).score: 435.0
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  34. Council for International Organizations of Medical Sciences (1998). International Ethical Guidelines for Biomedical Research Involving Human Subjects. Geneva: CIOMS, 2002. 16. Resnik DB. The Ethics of HIV Research in Developing Nations. [REVIEW] Bioethics 12:286-206.score: 435.0
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  35. Ana Smith Iltis (ed.) (2006). Research Ethics. Routledge.score: 432.0
    Medicine in the twenty-first century is increasingly reliant on research to guarantee the safety and efficacy of medical interventions. As a result, the need to understand the ethical issues that research generates is becoming essential. This volume introduces the principal areas of concern in research on human subjects, offering a framework for understanding research ethics, and the relationship between ethics and compliance. Research Ethics brings together leading scholars in bioethics and the topics (...)
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  36. Aurora Plomer (2005). The Law and Ethics of Medical Research: International Bioethics and Human Rights. Cavendish.score: 402.0
    This book examines the controversies surrounding biomedical research in the twenty-first century from a human rights perspective, analyzing the evolution and ...
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  37. Olubunmi A. Ogunrin, Temidayo O. Ogundiran & Clement Adebamowo (2013). Development and Pilot Testing of an Online Module for Ethics Education Based on the Nigerian National Code for Health Research Ethics. BMC Medical Ethics 14 (1):1-.score: 390.0
    Background: The formulation and implementation of national ethical regulations to protect research participants is fundamental to ethical conduct of research. Ethics education and capacity are inadequate in developing African countries. This study was designed to develop a module for online training in research ethics based on the Nigerian National Code of Health Research Ethics and assess its ease of use and reliability among biomedical researchers in Nigeria.MethodologyThis was a three-phased evaluation study. Phase (...)
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  38. Alan J. Kearns (2014). Catholic Social Teaching as a Framework for Research Ethics. Journal of Academic Ethics 12 (2):145-159.score: 390.0
    The importance of having ethical oversight in research that is carried out on humans is well established. Research ethics, which is mainly influenced by a biomedical ethical framework, aims to ensure that the well-being and the rights of research participants are upheld and that any potential risks and harms are reduced. However, research is also considered to be a social activity with social effects. Therefore the principles of Catholic Social Teaching as a framework for (...)
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  39. Benjamin Sachs (2011). Going From Principles to Rules in Research Ethics. Bioethics 25 (1):9-20.score: 381.0
    In research ethics there is a canon regarding what ethical rules ought to be followed by investigators vis-à-vis their treatment of subjects and a canon regarding what fundamental ethical principles apply to the endeavor. What I aim to demonstrate here is that several of the rules find no support in the principles. This leaves anyone who would insist that we not abandon those rules in the difficult position of needing to establish that we are nevertheless justified in believing (...)
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  40. Rebecca Dresser (2006). Private-Sector Research Ethics: Marketing or Good Conflicts Management? The 2005 John J. Conley Lecture on Medical Ethics. [REVIEW] Theoretical Medicine and Bioethics 27 (2):115-139.score: 381.0
    Pharmaceutical companies are major sponsors of biomedical research. Most scholars and policymakers focus their attention on government and academic oversight activities, however. In this article, I consider the role of pharmaceutical companies’ internal ethics statements in guiding decisions about corporate research and development (R&D). I review materials from drug company websites and contributions from the business and medical ethics literature that address ethical responsibilities of businesses in general and pharmaceutical companies in particular. I discuss positive (...)
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  41. Morenike Oluwatoyin Folayan, Aisha Adaranijo, Florita Durueke, Ademola Ajuwon, Adebayo Adejumo, Oliver Ezechi, Kola Oyedeji & Olayide Akanni (2012). Impact of Three Years Training on Operations Capacities of Research Ethics Committees in Nigeria. Developing World Bioethics 12 (3):1-14.score: 381.0
    This paper describes a three-year project designed to build the capacity of members of research ethics committes to perform their roles and responsibilities efficiently and effectively. The project participants were made up of a cross-section of the membership of 13 Research Ethics Committees (RECs) functioning in Nigeria. They received training to develop their capacity to evaluate research protocols, monitor trial implementation, provide constructive input to trial staff, and assess the trial's success in promoting community engagement (...)
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  42. Keymanthri Moodley & Landon Myer (2007). Health Research Ethics Committees in South Africa 12 Years Into Democracy. BMC Medical Ethics 8 (1):1-8.score: 378.0
    Background Despite the growth of biomedical research in South Africa, there are few insights into the operation of Research Ethics Committees (RECs) in this setting. We investigated the composition, operations and training needs of health RECs in South Africa against the backdrop of national and international guidelines. Methods The 12 major health RECs in South Africa were surveyed using semi-structured questionnaires that investigated the composition and functions of each REC as well as the operational issues facing (...)
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  43. Jérôme Ateudjieu, John Williams, Marie Hirtle, Cédric Baume, Joyce Ikingura, Alassane Niaré & Dominique Sprumont (2010). Training Needs Assessment in Research Ethics Evaluation Among Research Ethics Committee Members in Three African Countries: Cameroon, Mali and Tanzania. Developing World Bioethics 10 (2):88-98.score: 372.0
    Background: As actors with the key responsibility for the protection of human research participants, Research Ethics Committees (RECs) need to be competent and well-resourced in order to fulfil their roles. Despite recent programs designed to strengthen RECs in Africa, much more needs to be accomplished before these committees can function optimally.Objective: To assess training needs for biomedical research ethics evaluation among targeted countries.Methods: Members of RECs operating in three targeted African countries were surveyed between (...)
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  44. Constantinos Deltas, Helenē Kalokairinou & Sabine Rogge (eds.) (2006). Progress in Science and the Danger of Hubris: Genetics, Transplantation, Stem Cell Research: Proceedings of the First International Conference on Medical Ethics, Nicosia, 24-26 September 2004. [REVIEW] Waxmann.score: 369.0
    Introduction The present volume contains the proceedings of the First International Conference on Medical Ethics which took place in Nicosia, from the 24th ...
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  45. Sara Svensson & Sven Ove Hansson (2007). Protecting People in Research: A Comparison Between Biomedical and Traffic Research. [REVIEW] Science and Engineering Ethics 13 (1):99-115.score: 360.0
    Traffic research shares a fundamental dilemma with other areas of empirical research in which humans are potentially put at risk. Research is justified because it can improve safety in the long run. Nevertheless, people can be harmed in the research situation. Hence, we need to balance short-term risks against long-term safety improvements, much as in other areas of research with human subjects. In this paper we focus on ethical issues that arise when human beings are (...)
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  46. Judge Christian Byk (2002). Conflicts of Interests and Access to Information Resulting From Biomedical Research: An International Legal Perspective. [REVIEW] Science and Engineering Ethics 8 (3):287-290.score: 360.0
    Recently adopted international texts have given a new focus on conflicts of interests and access to information resulting from biomedical research. They confirmed ethical review committees as a central point to guarantee individual rights and the effective application of ethical principles. Therefore specific attention should be paid in giving such committees all the facilities necessary to keep them independent and qualified.
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  47. Emma Keuleyan (2010). Liberty to Decide on Dual Use Biomedical Research: An Acknowledged Necessity. Science and Engineering Ethics 16 (1):43-58.score: 360.0
    Humanity entered the twenty-first century with revolutionary achievements in biomedical research. At the same time multiple “dual-use” results have been published. The battle against infectious diseases is meeting new challenges, with newly emerging and re-emerging infections. Both natural disaster epidemics, such as SARS, avian influenza, haemorrhagic fevers, XDR and MDR tuberculosis and many others, and the possibility of intentional mis-use, such as letters containing anthrax spores in USA, 2001, have raised awareness of the real threats. Many great men, (...)
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  48. Mindaugas Broga, Goran Mijaljica, Marcin Waligora, Aime Keis & Ana Marusic (2013). Publication Ethics in Biomedical Journals From Countries in Central and Eastern Europe. Science and Engineering Ethics (1):1-11.score: 356.0
    Publication ethics is an important aspect of both the research and publication enterprises. It is particularly important in the field of biomedical science because published data may directly affect human health. In this article, we examine publication ethics policies in biomedical journals published in Central and Eastern Europe. We were interested in possible differences between East European countries that are members of the European Union (Eastern EU) and South-East European countries (South-East Europe) that are not (...)
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  49. Janet Borgerson (2005). Addressing the 'Global Basic Structure' in the Ethics of International Health Research Involving Human Subjects. Journal of Philosophical Research 30:235-249.score: 352.0
    The context of international health research involving human subjects, and this should appear obvious, is the human community. As such, basic questions of how human beings should be treated by other human beings, particularly in situations of unequal power – e.g., in the form of control, choice, or opportunity – lay at the foundations of related ethical discourse when ethics are discussed at all. I trace a narrative that follows upon a recent revision process of international guidelines for (...)
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  50. Hub Zwart (2010). The Nobel Prize as a Reward Mechanism in the Genomics Era: Anonymous Researchers, Visible Managers and the Ethics of Excellence. [REVIEW] Journal of Bioethical Inquiry 7 (3):299-312.score: 351.0
    The Human Genome Project (HGP) is regarded by many as one of the major scientific achievements in recent science history, a large-scale endeavour that is changing the way in which biomedical research is done and expected, moreover, to yield considerable benefit for society. Thus, since the completion of the human genome sequencing effort, a debate has emerged over the question whether this effort merits to be awarded a Nobel Prize and if so, who should be the one(s) to (...)
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