Search results for 'Biomedical Research ethics' (try it on Scholar)

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  1.  29
    Kiarash Aramesh (2015). A Brief History of Biomedical Research Ethics in Iran: Conflict of Paradigms. Developing World Bioethics 15 (2):107-112.
    During the past two decades, Iran has experienced a noteworthy growth in its biomedical research sector. At the same time, ethical concerns and debates resulting from this burgeoning enterprise has led to increasing attention paid to biomedical ethics. In Iran, Biomedical research ethics and research oversight passed through major periods during the past decades, separated by a paradigm shift. Period 1, starting from the early 1970s, is characterized by research paternalism and (...)
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  2.  23
    Christopher Tollefsen (2008). Biomedical Research and Beyond: Expanding the Ethics of Inquiry. Routledge.
    Biomedical Research and Beyond: Expanding the Ethics of Inquiry investigates the ethics of biomedical and scientific inquiry, including embryonic research, animal research, genetic enhancement, and fairness in research in the developing world. Core concerns of biomedical and scientific research ethics are then shown also to be key in humanistic areas of inquiry. Biomedical Research and Beyond concludes with a discussion of the virtues that all inquirers, scientific, medical, (...)
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  3.  9
    Merryn Ekberg (2012). Reassessing the Role of the Biomedical Research Ethics Committee. Journal of Academic Ethics 10 (4):335-352.
    The role of the Research Ethics Committee (REC) in the design, conduct and dissemination of scientific research is still evolving and many important questions remain unanswered. Hence, the aim of this paper is to address some of the uncertainty that exists around the role and responsibilities of RECs and to discuss some of the controversy that exists over the criteria that RECs should follow when evaluating a research proposal. The discussion is organised around five of the (...)
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  4.  1
    Sylvie Vandoolaeghe, Alessandra Blaizot, Danie Boudiguet, Valérie Bougault, Eduardo Dei Cas, Benoît Foligne, Anne Goffard, Hélène Lefranc, Bénédicte Oxombre, Thomas Trentesaux, Bernard Vandenbunder, Isabelle Wolowczuk, Laurence Delhaes & The “Ethic and Research” Working Group (2015). A Charter for Biomedical Research Ethics in a Progressive, Caring Society. Philosophy, Ethics, and Humanities in Medicine 10 (1):1-6.
    BackgroundGiven that advances in research continuously raise new ethical issues, a multidisciplinary working group of investigators involved in biomedical research has gathered to discuss and compare ethical viewpoints in their daily practice.MethodsThe working group has drafted a Charter for Ethics in Biomedical Research that encompasses all the steps in the research process, i.e. from the initial idea to analysis and publication of the results.ResultsBased on key principles for ethically responsible research, the Charter (...)
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  5.  57
    Baruch A. Brody (1998). The Ethics of Biomedical Research: An International Perspective. Oxford University Press.
    A broad critical review of national policies on biomedical research - human, epidemiologic, clinical trials, genetic, reproductive, etc.
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  6.  62
    Barbara K. Redman (2014). Review of Measurement Instruments in Research Ethics in the Biomedical Sciences, 2008−2012. [REVIEW] Research Ethics 10 (3):141-150.
    There is an urgent need in biomedical science to understand whether regulations are being met, prerequisite to goals of subject protection and integrity in research practice. This article presents an update of a 2006 summary of measurement instruments in research ethics with psychometric information in the years 2008−2012. A review of 25 instruments identified seven used in the time period 2008−2012 and which had accumulated at least one study of its psychometric qualities beyond its developmental phase. (...)
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  7. Angeliki Kerasidou & Michael Parker (2014). Does Science Need Bioethicists? Ethics and Science Collaboration in Biomedical Research. Research Ethics 10 (4):214-226.
    Biomedical research is an increasingly multidisciplinary activity bringing together a range of different academic fields and forms of expertise to investigate diseases that are increasingly understood to be complex and multifactorial. Recently the discipline of ethics has been starting to find a place in large-scale biomedical collaborations. In this article we draw from our experience of working with the Malaria Genomic Epidemiology Network and other research projects to reflect upon the integration of ethics into (...)
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  8.  16
    E. Lamas, M. Ferrer, A. Molina, R. Salinas, A. Hevia, A. Bota, D. Feinholz, M. Fuchs, R. Schramm, J. -C. Tealdi & S. Zorrilla (2010). A Comparative Analysis of Biomedical Research Ethics Regulation Systems in Europe and Latin America with Regard to the Protection of Human Subjects. Journal of Medical Ethics 36 (12):750-753.
    The European project European and Latin American Systems of Ethics Regulation of Biomedical Research Project (EULABOR) has carried out the first comparative analysis of ethics regulation systems for biomedical research in seven countries in Europe and Latin America, evaluating their roles in the protection of human subjects. We developed a conceptual and methodological framework defining ‘ethics regulation system for biomedical research’ as a set of actors, institutions, codes and laws involved in (...)
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  9.  18
    David Koepsell, Robert Arp, Jennifer Fostel & Barry Smith (2009). Creating a Controlled Vocabulary for the Ethics of Human Research: Towards a Biomedical Ethics Ontology. Journal of Empirical Research on Human Research Ethics 4 (1):43-58.
    Ontologies describe reality in specific domains in ways that can bridge various disciplines and languages. They allow easier access and integration of information that is collected by different groups. Ontologies are currently used in the biomedical sciences, geography, and law. A Biomedical Ethics Ontology would benefit members of ethics committees who deal with protocols and consent forms spanning numerous fields of inquiry. There already exists the Ontology for Biomedical Investigations (OBI); the proposed BMEO would interoperate (...)
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  10. Matti Häyry, Tuija Takala & Peter Herissone-Kelly (eds.) (2007). Ethics in Biomedical Research: International Perspectives. Brill | Rodopi.
    This book deals with the international assessment and regulation of biomedical research. In its chapters, some of the leading figures in today’s bioethics address questions centred on global development, scientific advances, and vulnerability. The series _Values In Bioethics_ makes available original philosophical books in all areas of bioethics, including medical and nursing ethics, health care ethics, research ethics, environmental ethics, and global bioethics.
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  11. Christopher O. Tollefsen (2008). Biomedical Research and Beyond: Expanding the Ethics of Inquiry. Routledge.
    What is the relationship between scientific research and ethics? Some think that science should be free from ethical and political considerations. _Biomedical Research and Beyond_ argues that ethical guidance is essential for all forms of inquiry, including biomedical and scientific research. By addressing some of the most controversial questions of biomedical research, such as embryonic research, animal research, and genetic enhancement research, the author argues for a rich moral framework for (...)
     
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  12. Christopher O. Tollefsen (2010). Biomedical Research and Beyond: Expanding the Ethics of Inquiry. Routledge.
    What is the relationship between scientific research and ethics? Some think that science should be free from ethical and political considerations. _Biomedical Research and Beyond_ argues that ethical guidance is essential for all forms of inquiry, including biomedical and scientific research. By addressing some of the most controversial questions of biomedical research, such as embryonic research, animal research, and genetic enhancement research, the author argues for a rich moral framework for (...)
     
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  13.  15
    Evelyne Decullier, Véronique Lhéritier & François Chapuis (2005). The Activity of French Research Ethics Committees and Characteristics of Biomedical Research Protocols Involving Humans: A Retrospective Cohort Study. [REVIEW] BMC Medical Ethics 6 (1):1-10.
    Background Clinical trials throughout the world must be evaluated by research ethics committees. No one has yet attempted to clearly quantify at the national level the activity of ethics committees and describe the characteristics of the protocols submitted. The objectives of this study were to describe 1) the workload and the activity of Research Ethics Committees in France, and 2) the characteristics of protocols approved on a nation-wide basis. Methods Retrospective cohort of 976 protocols approved (...)
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  14.  11
    Matthew Weed (2004). Ethics, Regulation, and Biomedical Research. Kennedy Institute of Ethics Journal 14 (4):361-368.
    : Controversy has surrounded the institutions that facilitate discussion and regulation of American biomedical research for years. Recent challenges to the legitimacy of the President's Council on Bioethics have been focused on stem cell research. These arguments represent an opportunity to reconsider the legislation under which stem cell research is regulated, as well as to consider preexisting bodies like the Recombinant DNA Advisory Committee and National Bioethics Advisory Commission. This paper proposes a Federal Life Sciences Policy (...)
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  15.  6
    Michael E. Frisina (2006). Commentary: The Application of Medical Ethics in Biomedical Research. Cambridge Quarterly of Healthcare Ethics 15 (4):439-441.
    The question of how to prevent the malevolent use of biomedical research is not new. It has its genesis in how to prevent any new technology, invention, or scientific discovery created for the benefit and advancement of human welfare being used for the expressed purpose of harming the human community. There is the ethical component, the social responsibility component, and the intent to preserve the beneficent characteristic of biomedical research at stake in this issue.
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  16.  19
    Robert C. Jones & Ray Greek (2014). A Review of the Institute of Medicine's Analysis of Using Chimpanzees in Biomedical Research. [REVIEW] Science and Engineering Ethics 20 (2):481-504.
    We argue that the recommendations made by the Institute of Medicine’s 2011 report, Chimpanzees in Biomedical and Behavioral Research : Assessing the Necessity, are methodologically and ethically confused. We argue that a proper understanding of evolution and complexity theory in terms of the science and ethics of using chimpanzees in biomedical research would have had led the committee to recommend not merely limiting but eliminating the use of chimpanzees in biomedical research. Specifically, we (...)
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  17.  1
    J. -P. Rwabihama, C. Girre & A. -M. Duguet (2010). Ethics Committees for Biomedical Research in Some African Emerging Countries: Which Establishment for Which Independence? A Comparison with the USA and Canada. Journal of Medical Ethics 36 (4):243-249.
    Context The conduct of medical research led by Northern countries in developing countries raises ethical questions. The assessment of research protocols has to be twofold, with a first reading in the country of origin and a second one in the country where the research takes place. This reading should benefit from an independent local ethical review of protocols. Consequently, ethics committees for medical research are evolving in Africa. Objective To investigate the process of establishing (...) committees and their independence. Method Descriptive study of 25 African countries and two North American countries. Data were recorded by questionnaire and interviews. Two visits of ethics committee meetings were conducted on the ground: over a period of 3 months in Kigali (Rwanda) and 2 months in Washington DC (USA). Results 22 countries participated in this study, 20 from Africa and two from North America. The response rate was 80%. 75% of local African committees developed into national ethics committees. During the last 5 years, these national committees have grown on a structural level. The circumstances of creation and the general context of underdevelopment remain the major challenges in Africa. Their independence could not be ensured without continuous training and efficient funding mechanisms. Institutional ethics committees are well established in USA and in Canada, whereas ethics committees in North America are weakened by the institutional affiliation of their members. Conclusion The process of establishing ethics committees could affect their functioning and compromise their independence in some African countries and in North America. (shrink)
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  18. Timothy F. Murphy (2004). Case Studies in Biomedical Research Ethics. Monograph Collection (Matt - Pseudo).
     
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  19. Robert J. Levine, Samuel Gorovitz & James Gallagher (eds.) (2000). Biomedical Research Ethics: Updating International Guidelines: A Consultation: Geneva, Switzerland, 15-17 March 2000. Cioms.
     
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  20. Jane A. Smith & Kenneth M. Boyd (eds.) (1991). Lives in the Balance: The Ethics of Using Animals in Biomedical Research: The Report of a Working Party of the Institute of Medical Ethics. Oxford University Press.
    This book is the result of a three-year study undertaken by a multidisciplinary working party of the Institute of Medical Ethic (UK). The group was chaired by a moral theologian, and its members included biological and ethological scientists, toxicologists, physicians, veterinary surgeons, an expert in alternatives to animal use, officers of animal welfare organizations, a Home Office Inspector, philosophers, and a lawyer. Coming from these different backgrounds, and holding a diversity of moral views, the members produced the agreed report as (...)
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  21.  4
    B. G. Haire (2013). Ethics of Medical Care and Clinical Research: A Qualitative Study of Principal Investigators in Biomedical HIV Prevention Research. Journal of Medical Ethics 39 (4):231-235.
    In clinical research there is a tension between the role of a doctor, who must serve the best interests of the patient, and the role of the researcher, who must produce knowledge that may not have any immediate benefits for the research participant. This tension is exacerbated in HIV research in low and middle income countries, which frequently uncovers comorbidities other than the condition under study. Some bioethicists argue that as the goals of medicine and those of (...)
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  22.  9
    Stevan Harnad (2007). Ethics of Open Access to Biomedical Research: Just a Special Case of Ethics of Open Access to Research. Philosophy, Ethics, and Humanities in Medicine 2 (1):31.
    The ethical case for Open Access (OA) (free online access) to research findings is especially salient when it is public health that is being compromised by needless access restrictions. But the ethical imperative for OA is far more general: It applies to all scientific and scholarly research findings published in peer-reviewed journals. And peer-to-peer access is far more important than direct public access. Most research is funded so as to be conducted and published, by researchers, in order (...)
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  23.  9
    Mary E. Sunderland & Rahul Uday Nayak (2015). Reengineering Biomedical Translational Research with Engineering Ethics. Science and Engineering Ethics 21 (4):1019-1031.
    It is widely accepted that translational research practitioners need to acquire special skills and knowledge that will enable them to anticipate, analyze, and manage a range of ethical issues. While there is a small but growing literature that addresses the ethics of translational research, there is a dearth of scholarship regarding how this might apply to engineers. In this paper we examine engineers as key translators and argue that they are well positioned to ask transformative ethical questions. (...)
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  24.  34
    Ana Smith Iltis (2002). Biomedical Research Ethics. Journal of Medicine and Philosophy 27 (5):515 – 522.
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  25.  7
    David Rodríguez-Arias & Christian Hervé (2005). A Review Of: “Timothy F. Murphy. 2004.Case Studies in Biomedical Research Ethics”. [REVIEW] American Journal of Bioethics 5 (2):64-66.
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  26. David Rodríguez-Arias & Christian Hervé (2005). A Review Of:“Timothy F. Murphy. 2004. Case Studies in Biomedical Research Ethics” Cambridge, MA: The MIT Press. 368 Pp. $29.00, Paperback. [REVIEW] American Journal of Bioethics 5 (2):64-66.
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  27.  1
    Fawaz Mzayek & David Resnik (2010). International Biomedical Research and Research Ethics Training in Developing Countries. Journal of Clinical Research and Bioethics 1 (1).
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  28.  10
    P. Sedgwick (1994). Lives in the Balance: The Ethics of Using Animals in Biomedical Research. Journal of Medical Ethics 20 (1):58-59.
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  29.  1
    Gayle Cartland Langley Rn & Anthony Egan Sj (2012). The Ethics of Care in Biomedical Research Committees. Journal of Clinical Research and Bioethics 3 (1).
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  30. Janet Borgerson (2005). Preparing Ethics for the Future: Addressing the “Global Basic Structure” in the Ethics of International Biomedical Research Involving Human Subjects. Journal of Philosophical Research 30 (Supplement):235-249.
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  31. Richard Zaner & Richard M. Zaner, A Critical Examination of Ethics in Health Care and Biomedical Research.
    My critique of the casuist proposal serves to highlight several points of interest. With its insistence on practical reason as at once more grounded in our moral history and more capable of appreciating the exigencies of moral discourse, Jonsen and Toulmin’s approach strikes me as very productive. It nevertheless has certain unanswered problems, as was suggested, and in the end remains too centered on the ethics consultant’s relation to the physician—both of which are simply taken for granted as having (...)
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  32.  16
    Thomas H. Murray & Josephine Johnston (eds.) (2010). Trust and Integrity in Biomedical Research: The Case of Financial Conflicts of Interest. Johns Hopkins University Press.
    This volume assesses the ethical, quantitative, and qualitative questions posed by the current financing of biomedical research.
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  33.  2
    Pēteris Zilgalvis (2002). The Council of Europe's Instruments on Biomedical Research: How is Conflict of Interest Addressed? [REVIEW] Science and Engineering Ethics 8 (3):277-281.
    Conflict of interest is an issue that has been put in the spotlight by the commercial application of the new biomedical technologies. This paper presents the approach of the Council of Europe and the binding legal instruments to deal with this problem. The main focus is on the Convention on Human Rights and Biomedicine, and its draft additional Protocol on Biomedical Research.
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  34.  11
    Jan Helge Solbakk (1991). Ethics Review Committees [in Biomedical Research] in the Nordic Countries: History, Organization, and Assignments. [REVIEW] HEC Forum 3 (4):215-220.
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  35.  5
    A. M. Chakrabarty (2002). Ethics in Biomedical Research: Practical Considerations. American Journal of Bioethics 2 (4):53 – 54.
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  36.  1
    John McMillan (2009). Review of Christopher O. Tollefsen, Biomedical Research and Beyond: Expanding the Ethics of Inquiry. [REVIEW] Notre Dame Philosophical Reviews 2009 (1).
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  37. M. Cho, H. T. Greely, D. Magnus & J. Maienschein (forthcoming). Developing a New Paradigm for Integrating Ethics and Biomedical Research: Proposal for a Benchside Consultation Program. American Society for Bioethics and Humanities/Canadian Bioethics Society Joint Meeting.
     
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  38. Susan Ellenberg, Thomas Fleming & David DeMets (2008). "(2006), A16. Brody, Baruch A. The Ethics of Biomedical Research: An International Perspective. New York: Oxford University Press, 1998. Capron, Alexander M." Experimentation with Human Beings: Light or Only Shadows?" Yale Journal of Health Policy, Law And. [REVIEW] Contemporary Issues in Bioethics 15 (1).
     
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  39. Council for International Organizations of Medical Sciences (1998). International Ethical Guidelines for Biomedical Research Involving Human Subjects. Geneva: CIOMS, 2002. 16. Resnik DB. The Ethics of HIV Research in Developing Nations. [REVIEW] Bioethics 12:286-206.
     
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  40.  31
    Ana Smith Iltis (ed.) (2006). Research Ethics. Routledge.
    Medicine in the twenty-first century is increasingly reliant on research to guarantee the safety and efficacy of medical interventions. As a result, the need to understand the ethical issues that research generates is becoming essential. This volume introduces the principal areas of concern in research on human subjects, offering a framework for understanding research ethics, and the relationship between ethics and compliance. Research Ethics brings together leading scholars in bioethics and the topics (...)
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  41. Ebbesen M. & Sundby A. (2015). A Philosophical Analysis of Informed Consent for Whole Genome Sequencing in Biobank Research by Use of Beauchamp and Childress’ Four Principles of Biomedical Ethics. Journal of Clinical Research and Bioethics 6 (6).
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  42.  45
    James V. Lavery (ed.) (2007). Ethical Issues in International Biomedical Research: A Casebook. Oxford University Press.
    No other volume has this scope. Students in bioethics, public and international health, and ethics will find this book particularly useful.
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  43.  10
    Aurora Plomer (2005). The Law and Ethics of Medical Research: International Bioethics and Human Rights. Cavendish.
    This book examines the controversies surrounding biomedical research in the twenty-first century from a human rights perspective, analyzing the evolution and ...
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  44.  8
    Susan Eastwood, Pamela Derish, Evangeline Leash & Stephen Ordway (1996). Ethical Issues in Biomedical Research: Perceptions and Practices of Postdoctoral Research Fellows Responding to a Survey. Science and Engineering Ethics 2 (1):89-114.
    We surveyed 1005 postdoctoral fellows by questionnaire about ethical matters related to biomedical research and publishing; 33% responded. About 18% of respondents said they had taken a course in research ethics, and about 31% said they had had a course that devoted some time to research ethics. A substantial majority stated willingness to grant other investigators, except competitors, access to their data before publication and to share research materials. Respondents’ opinions about contributions justifying (...)
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  45.  24
    Olubunmi A. Ogunrin, Temidayo O. Ogundiran & Clement Adebamowo (2013). Development and Pilot Testing of an Online Module for Ethics Education Based on the Nigerian National Code for Health Research Ethics. BMC Medical Ethics 14 (1):1-.
    Background: The formulation and implementation of national ethical regulations to protect research participants is fundamental to ethical conduct of research. Ethics education and capacity are inadequate in developing African countries. This study was designed to develop a module for online training in research ethics based on the Nigerian National Code of Health Research Ethics and assess its ease of use and reliability among biomedical researchers in Nigeria.MethodologyThis was a three-phased evaluation study. Phase (...)
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  46.  4
    Alan J. Kearns (2014). Catholic Social Teaching as a Framework for Research Ethics. Journal of Academic Ethics 12 (2):145-159.
    The importance of having ethical oversight in research that is carried out on humans is well established. Research ethics, which is mainly influenced by a biomedical ethical framework, aims to ensure that the well-being and the rights of research participants are upheld and that any potential risks and harms are reduced. However, research is also considered to be a social activity with social effects. Therefore the principles of Catholic Social Teaching as a framework for (...)
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  47. Francis Kombe (2015). Enhancing Quality and Integrity in Biomedical Research in Africa: An International Call for Greater Focus, Investment and Standardisation in Capacity Strengthening for Frontline Staff. BMC Medical Ethics 16 (1):1-5.
    The integrity of biomedical research depends heavily on the quality of research data collected. In turn, data quality depends on processes of data collection, a task undertaken by frontline research staff in many research programmes in Africa and elsewhere. These frontline research staff often have additional responsibilities including translating and communicating research in local languages, seeking informed consent for study participation and maintaining supportive relationships between research institutions and study participants and wider (...)
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  48.  36
    Tom L. Beauchamp (2009). Principles of Biomedical Ethics. Oxford University Press.
    This edition represents a thorough-going revision of what has become a classic text in biomedical ethics. Major structural changes mark the revision. The authors have added a new concluding chapter on methods that, along with its companion chapter on moral theory, emphasizes convergence across theories, coherence in moral justification, and the common morality. They have simplified the opening chapter on moral norms which introduces the framework of prima facie moral principles and ways to specify and balance them. (...)
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  49.  57
    Keymanthri Moodley & Landon Myer (2007). Health Research Ethics Committees in South Africa 12 Years Into Democracy. BMC Medical Ethics 8 (1):1-8.
    Background Despite the growth of biomedical research in South Africa, there are few insights into the operation of Research Ethics Committees (RECs) in this setting. We investigated the composition, operations and training needs of health RECs in South Africa against the backdrop of national and international guidelines. Methods The 12 major health RECs in South Africa were surveyed using semi-structured questionnaires that investigated the composition and functions of each REC as well as the operational issues facing (...)
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  50.  20
    Rebecca Dresser (2006). Private-Sector Research Ethics: Marketing or Good Conflicts Management? The 2005 John J. Conley Lecture on Medical Ethics. [REVIEW] Theoretical Medicine and Bioethics 27 (2):115-139.
    Pharmaceutical companies are major sponsors of biomedical research. Most scholars and policymakers focus their attention on government and academic oversight activities, however. In this article, I consider the role of pharmaceutical companies’ internal ethics statements in guiding decisions about corporate research and development (R&D). I review materials from drug company websites and contributions from the business and medical ethics literature that address ethical responsibilities of businesses in general and pharmaceutical companies in particular. I discuss positive (...)
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