, Pietroski and Rey ([1995]) suggested a reconstruction of ceteris paribus (CP)-laws, which — as they claim — saves CP-laws from vacuity. This discussion note is intended to show that, although Pietroski and Rey's reconstruction is an improvement in comparison to previous suggestions, it cannot avoid the result that CP-laws are almost vacuous. It is proved that if Cx is an arbitrary (nomological) event-type which has independently identifiable deterministic causes, then for every other (nomological) event-type Ax which is not strictly (...) connected with Cx or with ¬Cx, ‘CP if Ax then Cx’ satisfies the conditions of Pietroski and Rey for CP-laws. It is also shown that Pietroski and Rey's reconstruction presupposes the assumption of determinism. The conclusion points towards some alternatives to Piectroski and Rey's reconstruction. (shrink)

The purpose of professional education programs is to prepare aspiring professionals for the challenges of practice within a particular profession. These programs typically seek to ensure the acquisition of necessary knowledge and skills, as well as providing opportunities for their application. While not denying the importance of knowledge and skills, this paper reconfigures professional education as a process of becoming. Learning to become a professional involves not only what we know and can do, but also who we are. It involves (...) integration of knowing, acting, and being in the form of professional ways of being that unfold over time. When a professional education program focuses on the acquisition and application of knowledge and skills, it falls short of facilitating their integration into professional ways of being. In addition, through such a focus on epistemology, ontology is overlooked. This paper explores what it means to develop professional ways of being where the focus is becoming, not simply knowing as an end in itself. (shrink)

This paper is concerned with a natural deduction system for First Degree Entailment (FDE). First, we exhibit a brief history of FDE and of combined systems whose underlying idea is used in developing the natural deduction system. Then, after presenting the language and a semantics of FDE, we develop a natural deduction system for FDE. We then prove soundness and completeness of the system with respect to the semantics. The system neatly represents the four-valued semantics for FDE.

In that Case Content Type Journal Article DOI 10.1007/s11673-010-9261-3 Authors Malcolm Parker, School of Medicine, University of Queensland, Brisbane, Australia Journal Journal of Bioethical Inquiry Online ISSN 1872-4353 Print ISSN 1176-7529.

Gap junction intercellular communication channels permit the exchange of small regulatory molecules and ions between neighbouring cells and coordinate cellular activity in diverse tissue and organ systems. These channels have short half‐lives and complex assembly and degradation pathways. Much of the recent work elucidating gap junction biogenesis has featured the use of connexins (Cx), the constituent proteins of gap junctions, tagged with reporter proteins such as Green Fluorescent Protein (GFP) and has illuminated the dynamics of channel assembly in live cells (...) by high‐resolution time‐lapse microscopy. With some studies, however, there are potential short‐comings associated with the GFP chimeric protein technologies. A recent report by Gaietta et al., has highlighted the use of recombinant proteins with tetracysteine tags attached to the carboxyl terminus of Cx43, which differentially labels ‘old’ and ‘new’ connexins thus opening up new avenues for studying temporal and spatial localisation of proteins and in situ trafficking events.1 BioEssays 24:876–880, 2002. © 2002 Wiley Periodicals, Inc. (shrink)

Intercellular communication (IC) is mediated by gap junctions (GJs) and hemichannels, which consist of proteins. This has been particularly well documented for the connexin (Cx) family. Initially, Cxs were thought to be the only proteins capable of GJ formation in vertebrates. About 10 years ago, however, a new GJ‐forming protein family related to invertebrate innexins (Inxs) was discovered in vertebrates, and named the pannexin (Panx) family. Panxs, which are structurally similar to Cxs, but evolutionarily distinct, have been shown to be (...) co‐expressed with Cxs in vertebrates. Both protein families show distinct properties and have their own particular function. Identification of the mechanisms that control Panx channel gating is a major challenge for future work. In this review, we focus on the specific properties and role of Panxs in normal and pathological conditions. (shrink)

I Want to comment on five passages where I have provoked disagreement by a previous discussion. In the first three, my discussion was in Philologus cx, 152–4, and my critic is Bruno Gentili in Quaderni Urbinati iv, 177–81. I was not the first to make an emendation in any of the three places, so that in defending the transmitted text Gentili is actually not only criticizing me but others such as Hermann, Naeke, O. Müller, Schoemann, Hunt, Murray, and Page.

In “The Irrelevance of the Diachronic Money-Pump Argument for Acyclicity,” The Journal of Philosophy CX, 8 (August 2013), 460-464, Johan E. Gustafsson contends that if Davidson, McKinsey and Suppes’ diachronic money-pump argument in their "Outlines of a Formal Theory of Value, I," Philosophy of Science 22 (1955), 140-160 is valid, so is the synchronic argument Gustafsson himself offers. He concludes that the latter renders irrelevant diachronic choice considerations in general, and the two best-known diachronic solutions to the money pump problem (...) in particular. I argue here that this reasoning is incorrect, and that Gustafsson’s synchronic argument is faulty on independent grounds. Specifically, it is based on a false analogy between the derivation of a synchronic ordinal ranking from a transitive series of pairwise comparisons, and the putative derivation of such a ranking from an intransitive series. The latter is not possible under the assumption of revealed preference theory, and is highly improbable even if that assumption is rejected. Moreover, Gustafsson’s argument raises issues of fidelity to the historical texts that must be addressed. I conclude that the money pump, and cyclical choice more generally, are necessarily diachronic; and therefore that the two best-known diachronic solutions to the money pump problem remain relevant. (shrink)

Through the second year, children’s copying behaviour shifts from a focus on emulating to a focus on imitating. This shift can be explained by a change in focus from copying others to satisfy cognitive motivations to copying in order to satisfy social motivations. As elegant and detailed as the shared circuits model (SCM) is, it misses this crucial, motivation-based feature of imitation.

The identity "relation" is misconceived since the syntax of "=" is misconceived as a relative term. Actually, "=" is syncategorematic; it forms (true) sentences with a nonpredicative syntax from pairs of (coreferring) flanking names, much as "&" forms (true) conjunctive sentences from pairs of (true) flanking sentences. In the conaming structure, nothing is predicated of the subject, other than, implicitly, its being so conamed. An identity sentence has both an objectual reading as a necessity about what is named, and also (...) a metalinguistic reading as a contingency about the names. Either way the claim about the subject referent has no extralinguistic content. The necessity of alteridentity (non-self-identity) statements is "lexical", due to contingencies of the names' reference, much like the necessity of analytic statements, due to contingencies of the predicates' sense, and unlike the necessity of logical truths (e.g., self-identities) whose truth is secured by syntax alone. Both alter-identity and analytic sentences are readable as objectual necessities and metalinguistic contingencies. Epistemically, alter-identity statements are not essentially unlike analyticities. "Greece is Hellas"/"g=h" and "Greeks are Hellenes"/"(x)(Gx<=>Hx)" are equally (un)informative; so too for "Azure is cobalt"/"a=c" and "Everything azure is cobalt"/"(x)(Ax<=>Cx)". The real epistemic contrast is between proper names (terms without predicative sense) and terms with a predicative sense (names and predicates of properties). Proper names refer to concrete objects, property names refer to abstract objects. That contrast is metaphysical and thus epistemic. (shrink)

I Want to comment on five passages where I have provoked disagreement by a previous discussion. In the first three, my discussion was in Philologus cx , 152–4, and my critic is Bruno Gentili in Quaderni Urbinati iv , 177–81. I was not the first to make an emendation in any of the three places, so that in defending the transmitted text Gentili is actually not only criticizing me but others such as Hermann, Naeke, O. Müller, Schoemann, Hunt, Murray, and (...) Page. (shrink)

The real reason for the apparent discontinuity between human and nonhuman minds is that all closely related hominids have become extinct. Nonetheless, I agree with Penn et al. that comparative psychology should aim to establish what cognitive traits humans share with other animals and what traits they do not share, because this could make profound contributions to genetics and neuroscience. There is, however, no consensus yet, and Penn et al.'s conclusion that it all comes down to one trait is premature.