Search results for 'DNA' (try it on Scholar)

923 found
Sort by:
  1. David B. Resnik (2001). DNA Patents and Scientific Discovery and Innovation: Assessing Benefits and Risks. Science and Engineering Ethics 7 (1):29-62.score: 24.0
    This paper focuses on the question of whether DNA patents help or hinder scientific discovery and innovation. While DNA patents create a wide variety of possible benefits (...)
    Direct download (6 more)  
     
    My bibliography  
     
    Export citation  
  2. Ayman Shabana (2012). Paternity Between Law and Biology: The Reconstruction of the Islamic Law of Paternity in the Wake of Dna Testing. Zygon 47 (1):214-239.score: 24.0
    Abstract: The discovery of DNA paternity tests has stirred a debate concerning the definition of paternity and whether the grounds for such a definition are legal or (...)
    Direct download (6 more)  
     
    My bibliography  
     
    Export citation  
  3. Amade M'charek (2008). Silent Witness, Articulate Collective: Dna Evidence and the Inference of Visible Traits. Bioethics 22 (9):519-528.score: 24.0
    DNA profiling is a well-established technology for use in the criminal justice system, both in courtrooms and elsewhere. The fact that DNA profiles are based on (...)non-coding DNA and do not reveal details about the physical appearance of an individual has contributed to the acceptability of this type of evidence. Its success in criminal investigation, combined with major innovations in the field of genetics, have contributed to a change of role for this type of evidence. Nowadays DNA evidence is not merely about identification, where trace evidence is compared to a sample taken from a suspect. An ever-growing role is anticipated for DNA profiling as an investigative tool, a technique aimed at generating a suspect where there is none. One of these applications is the inference of visible traits. As this article will show, racial classifications are at the heart of this application. The Netherlands and its legal regulation of 'externally visible traits' will serve as an example. It will be shown that, to make this technology work, a large number of actors has to be enrolled and their articulations invited. This indicates that instead of a 'silent witness', a DNA profile should rather be seen as an 'articulate collective'. Based on two cases, I argue that the normativity of visible traits is context-dependent. Taking into account the practices in which technology is put to use alerts us to novel ethical questions raised by their application. (shrink)
    Direct download (6 more)  
     
    My bibliography  
     
    Export citation  
  4. Alexis De Tiège, Koen Tanghe, Johan Braeckman & Yves Van de Peer (2014). From DNA- to NA-Centrism and the Conditions for Gene-Centrism Revisited. Biology and Philosophy 29 (1):55-69.score: 24.0
    First theWeismann barrierand later on Francis Crickscentral dogmaof molecular biology nourished the gene-centric paradigm of life, i.e., the conception of the (...)
    Direct download (3 more)  
     
    My bibliography  
     
    Export citation  
  5. Pierre-Luc Germain, Emanuele Ratti & Federico Boem (2014). Junk or Functional DNA? ENCODE and the Function Controversy. Biology and Philosophy 29 (6):807-831.score: 24.0
    In its last round of publications in September 2012, the Encyclopedia Of DNA Elements (ENCODE) assigned a biochemical function to most of the human genome, which was (...)
    Direct download (3 more)  
     
    My bibliography  
     
    Export citation  
  6. Marcia J. Weiss (2004). Beware! Uncle Sam has Your DNA: Legal Fallout From its Use and Misuse in the U.s. [REVIEW] Ethics and Information Technology 6 (1):55-63.score: 24.0
    Technology has provided state and federal governments with huge collections of DNA samples and identifying profiles stored in databanks. That information can be used to solve crimes (...)
    Direct download (13 more)  
     
    My bibliography  
     
    Export citation  
  7. Doogab Yi (2008). Cancer, Viruses, and Mass Migration: Paul Berg's Venture Into Eukaryotic Biology and the Advent of Recombinant DNA Research and Technology, 1967-1980. [REVIEW] Journal of the History of Biology 41 (4):589 - 636.score: 24.0
    The existing literature on the development of recombinant DNA technology and genetic engineering tends to focus on Stanley Cohen and Herbert Boyer's recombinant DNA cloning technology (...)and its commercialization starting in the mid-1970s. Historians of science, however, have pointedly noted that experimental procedures for making recombinant DNA molecules were initially developed by Stanford biochemist Paul Berg and his colleagues, Peter Lobban and A. Dale Kaiser in the early 1970s. This paper, recognizing the uneasy disjuncture between scientific authorship and legal invention in the history of recombinant DNA technology, investigates the development of recombinant DNA technology in its full scientific context. I do so by focusing on Stanford biochemist Berg's research on the genetic regulation of higher organisms. As I hope to demonstrate, Berg's new venture reflected a mass migration of biomedical researchers as they shifted from studying prokaryotic organisms like bacteria to studying eukaryotic organisms like mammalian and human cells. It was out of this boundary crossing from prokaryotic to eukaryotic systems through virus model systems that recombinant DNA technology and other significant new research techniques and agendas emerged. Indeed, in their attempt to reconstitute 'life' as a research technology, Stanford biochemists' recombinant DNA research recast genes as a sequence that could be rewritten thorough biochemical operations. The last part of this paper shifts focus from recombinant DNA technology's academic origins to its transformation into a genetic engineering technology by examining the wide range of experimental hybridizations which occurred as techniques and knowledge circulated between Stanford biochemists and the Bay Area's experimentalists. Situating their interchange in a dense research network based at Stanford's biochemistry department, this paper helps to revise the canonized history of genetic engineering's origins that emerged during the patenting of Cohen-Boyer's recombinant DNA cloning procedures. (shrink)
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  8. Rogeer Hoedemaekers & Wim Dekkers (2002). The Ontological Status of Human DNA: Is It Not First and Foremost a Biological ``File Self''? Theoretical Medicine and Bioethics 23 (4-5):377-395.score: 24.0
    This paper investigates which of the variouslegal notions proposed for human DNA is themost appropriate from an ontological viewpointunique legal status, private property, commonproperty, person, or (...) information. The focus is onthe difficulties that private property, commonproperty and person present. By usingHarré''s notion of ``file-self'''' we arguethat, ontologically, the most appropriate legalnotion to be applied is information. This hasconsequences for storage, control and use ofgenetic information as well as identifiablehuman body material. (shrink)
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  9. Miguel García-Sancho (2010). A New Insight Into Sanger's Development of Sequencing: From Proteins to DNA, 1943-1977. [REVIEW] Journal of the History of Biology 43 (2):265 - 323.score: 24.0
    Fred Sanger, the inventor of the first protein, RNA and DNA sequencing methods, has traditionally been seen as a technical scientist, engaged in laboratory bench work and (...)
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  10. Áurea Anguera de Sojo, Juan Ares, María Aurora Martínez, Juan Pazos, Santiago Rodríguez & José Gabriel Zato (2014). Serendipity and the Discovery of DNA. Foundations of Science 19 (4):387-401.score: 24.0
    This paper presents the manner in which the DNA, the molecule of life, was discovered. Unlike what many people, even biologists, believe, it was Johannes Friedrich Miescher (...)
    Direct download (2 more)  
     
    My bibliography  
     
    Export citation  
  11. Doris Schröder & Garrath Williams (2002). DNA-Banken und Treuhandschaft [DNA Banking and Trusteeship]. Ethik in der Medizin 14 (2):84-95.score: 24.0
    Definition of the problem:The frequency and scope of human genetic banking has increased significantly in recent years and is set to expand still further. Two of (...)the major growth areas in medical research, pharmacogenomics and population genetics, rely on large DNA banks to provide extensive, centralised and standardised genetic information as well as clinical and personal data. This development raises ethical concerns. Arguments and conclusion: Our article focuses on the appropriateness of informed consent as a means to safeguard both research subjectsrights and their good will. It will be argued that information requirements are extensive, with regard to non-therapeutic research, feedback, type of consent and possible breaches of confidentiality as well as possible implications for third parties. Given the demand of these requirements and the danger that research facilitated by these huge DNA banks may not reflect public priorities, it is argued that the research needs be steered by trustees to ensure that the altruistic act of sample donation contributes to the public good. (shrink)
    Translate to English
    | Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  12. [deleted]James P. Morris Allison Jack, Jessica J. Connelly (2012). DNA Methylation of the Oxytocin Receptor Gene Predicts Neural Response to Ambiguous Social Stimuli. Frontiers in Human Neuroscience 6.score: 24.0
    Oxytocin and its receptor (OXTR) play an important role in a variety of social perceptual and affiliative processes. Individual variability in social information processing likely has a (...)
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  13. Marianne Boenink & Simone van der Burg (2010). Informed Decision Making About Predictive DNA Tests: Arguments for More Public Visibility of Personal Deliberations About the Good Life. [REVIEW] Medicine, Health Care and Philosophy 13 (2):127-138.score: 24.0
    Since its advent, predictive DNA testing has been perceived as a technology that may have considerable impact on the quality of peoples life. The decision whether (...)or not to use this technology is up to the individual client. However, to enable well considered decision making both the negative as well as the positive freedom of the individual should be supported. In this paper, we argue that current professional and public discourse on predictive DNA-testing is lacking when it comes to supporting positive freedom, because it is usually framed in terms of risk and risk management. We show how thisrisk discoursesteers thinking on the good life in a particular way. We go on to argue that empirical research into the actual deliberation and decision making processes of individuals and families may be used to enrich the environment of personal deliberation in three ways: (1) it points at a richer set of values that deliberators can take into account, (2) it acknowledges the shared nature of genes, and (3) it shows how one might frame decisions in a non-binary way. We argue that the public sharing and discussing of stories about personal deliberations offers valuable input for others who face similar choices: it fosters their positive freedom to shape their view of the good life in relation to DNA-diagnostics. We conclude by offering some suggestions as to how to realize such public sharing of personal stories. (shrink)
    Direct download (3 more)  
     
    My bibliography  
     
    Export citation  
  14. [deleted]Allison Jack, Jessica J. Connelly & James P. Morris (2012). DNA Methylation of the Oxytocin Receptor Gene Predicts Neural Response to Ambiguous Social Stimuli. Frontiers in Human Neuroscience 6.score: 24.0
    Oxytocin and its receptor (OXTR) play an important role in a variety of social perceptual and affiliative processes. Individual variability in social information processing likely has a (...)
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  15. John Richards (ed.) (1978). Recombinant Dna: Science, Ethics, and Politics. Academic Press.score: 24.0
  16. Gerald Weissmann (2009). Mortal and Immortal Dna: Science and the Lure of Myth. Bellevue Literary Press.score: 24.0
    Mortal and immortal DNA : Craig Venter and the lure of "lamia" -- Homeopathy : Holmes, hogwarts, and the Prince of Wales -- Citizen Pinel and the madman at Bellevue (...) -- The experimental pathology of stress : Hans Selye to Paris Hilton -- Gore's fever and Dante's Inferno : Chikungunya reaches Ravenna -- Giving things their proper names : Carl Linnaeus and W.H. Auden -- Spinal irritation and fibromyalgia : Lincoln's surgeon general and the three graces -- Tithonus and the fruit fly : new science and old myths -- Swiftboating "America the beautiful" : Katharine Lee Bates and a Boston marriage -- Nothing makes sense in medicine except in the light of biology -- Apply directly to the forehead : Holmes, Zola, and Hennapecia -- Elizabeth Blackwell breaks the bonds -- Chronic lyme disease and medically unexplained syndromes -- Eugenics and the immigrant : Rosalyn Yalow and Rita Levi-Montalcini -- Science in the Middle East : Robert Koch and the cholera war -- How to win a Nobel prize : thinking inside and outside the box -- Homer Smith and the lungfish : the last gasp of intelligent design -- DDT is back : let us spray! -- Academic boycotts and the Royal Society -- Teach evolution, learn science : John William Draper and the "bone bill" -- Diderot and the yeti crab : the encyclopedias of life -- Dengue fever in Rio : Macumba versus Voltaire. (shrink)
     
    My bibliography  
     
    Export citation  
  17. Reed Richter, DNA, Masterpieces, and Abortion: Shifting the Grounds of the Debate.score: 21.0
    Writers, philosophers, and theologians have oft made the comparison between being a mature human being and a masterpiece work of art or design. Employing the analogy between (...)
    Translate to English
    | Direct download (2 more)  
     
    My bibliography  
     
    Export citation  
  18. Monika Piotrowska (2009). The Theoretical Costs of DNA Barcoding. Biological Theory 4 (3):235-239.score: 21.0
    Direct download (3 more)  
     
    My bibliography  
     
    Export citation  
  19. Paul Z. Goldstein & Rob DeSalle (2011). Integrating DNA Barcode Data and Taxonomic Practice: Determination, Discovery, and Description. Bioessays 33 (2):135-147.score: 21.0
    Direct download (5 more)  
     
    My bibliography  
     
    Export citation  
  20. Thomas G. Hofmann, Carolina Glas & Nadja Bitomsky (2013). HIPK2: A Tumour Suppressor That Controls DNA DamageInduced Cell Fate and Cytokinesis. Bioessays 35 (1):55-64.score: 21.0
  21. Susan M. Rosenberg, Chandan Shee, Ryan L. Frisch & P. J. Hastings (2012). StressInduced Mutation Via DNA Breaks in Escherichia Coli: A Molecular Mechanism with Implications for Evolution and Medicine. Bioessays 34 (10):885-892.score: 21.0
    Direct download (5 more)  
     
    My bibliography  
     
    Export citation  
  22. Herman T. Tavani & Maria Bottis (2010). The Consent Process in Medical Research Involving DNA Databanks: Some Ethical Implications and Challenges. Acm Sigcas Computers and Society 40 (2):11-21.score: 21.0
    No categories
    Direct download (6 more)  
     
    My bibliography  
     
    Export citation  
  23. Dvir Aran & Asaf Hellman (2014). Unmasking Risk Loci: DNA Methylation Illuminates the Biology of Cancer Predisposition. Bioessays 36 (2):184-190.score: 21.0
    Direct download (3 more)  
     
    My bibliography  
     
    Export citation  
  24. Andrei Kuzminov (2013). Inhibition of DNA Synthesis Facilitates Expansion of LowComplexity Repeats. Bioessays 35 (4):306-313.score: 21.0
    Direct download (5 more)  
     
    My bibliography  
     
    Export citation  
  25. Björn Schumacher (2009). TranscriptionBlocking DNA Damage in Aging: a Mechanism for Hormesis. Bioessays 31 (12):1347-1356.score: 21.0
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  26. Keith E. Szulwach & Peng Jin (2014). Integrating DNA Methylation Dynamics Into a Framework for Understanding Epigenetic Codes. Bioessays 36 (1):107-117.score: 21.0
    Direct download (3 more)  
     
    My bibliography  
     
    Export citation  
  27. Alexander Vologodskii (2010). DNA Supercoiling Helps to Unlink Sister Duplexes After Replication. Bioessays 32 (1):9-12.score: 21.0
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  28. Gloria G. Fortes, Camilla F. Speller, Michael Hofreiter & Turi E. King (2013). Phenotypes From Ancient DNA: Approaches, Insights and Prospects. Bioessays 35 (8):690-695.score: 21.0
  29. Wolfram Henn (1998). Der DNA-ChipSchlüsseltechnologie Für Ethisch Problematische Neue Formen Genetischen Screenings? Ethik in der Medizin 10 (3):128-137.score: 21.0
    Definition of the problem: The development of molecular genetics has provided tools not only for the diagnosis of genetic diseases and disease dispositions in affected individuals, but (...)
    No categories
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  30. Benoit Miotto & Yacine Graba (2010). Control of DNA Replication: A New Facet of Hox Proteins? Bioessays 32 (9):800-807.score: 21.0
    Direct download (5 more)  
     
    My bibliography  
     
    Export citation  
  31. James P. Reddington, Duncan Sproul & Richard R. Meehan (2014). DNA Methylation Reprogramming in Cancer: Does It Act by ReConfiguring the Binding Landscape of Polycomb Repressive Complexes? Bioessays 36 (2):134-140.score: 21.0
    Direct download (3 more)  
     
    My bibliography  
     
    Export citation  
  32. Ricard V. Solé (2010). Genome Size, SelfOrganization and DNA's Dark Matter. Complexity 16 (1):20-23.score: 21.0
    No categories
    Direct download (5 more)  
     
    My bibliography  
     
    Export citation  
  33. C. Kenneth Waters, Beyond Theoretical Reduction and Layer-Cake Antireduction: How DNA Retooled Genetics and Transformed Biological Practice.score: 18.0
    Watson and Cricks discovery of the structure of DNA led to developments that transformed many biological sciences. But what were the relevant developments and how did (...)they transform biology? Much of the philosophical discussion concerning this question can be organized around two opposing views: theoretical reductionism and layer-cake antireductionism. Theoretical reductionist and their anti-reductionist foes hold two assumptions in common. First, both hold that biological knowledge is structured like a layer cake, with some biological sciences, such as molecular biology cast at lower levels of organization, and others, such as classical genetics, cast at higher levels. Second, both assume that scientific knowledge is structured by theory and that the productivity of scientific research depends on whether the underlying theory identifies the fundamentals upon which the phenomena to be explained and investigated depend. In the first part of this paper, I challenge these assumptions. In the second part, I show how recasting the basic theory of classical genetics made it possible to retool the methodologies of genetics. It was the investigative power of these retooled methodologies, and not the explanatory power of a gene-based theory, that transformed biology. (shrink)
    Direct download  
     
    My bibliography  
     
    Export citation  
  34. Stuart Hameroff, Is DNA a Quantum Computer?score: 18.0
    A recent paper by Rieper, Anders and Vedral (arxiv.org/abs/1006.4053: The Relevance Of Continuous Variable Entanglement In DNA) suggests that quantum entanglement among base pairs (...)in the DNA double helix stabilizes the molecule. A summary of their paper is reported in MIT Technology Review (http://www.technologyreview.com/blog/arxiv/25375/) is below.. (shrink)
    Translate to English
    | Direct download  
     
    My bibliography  
     
    Export citation  
  35. Rebecca Dresser (2011). Families and Forensic DNA Profiles. Hastings Center Report 41 (3):11-12.score: 18.0
    Law enforcement officials often turn to DNA identification methods to detectand rule outpossible offenders. Every state operates its own database of convicted offenders' DNA profiles; some (...) states store profiles of arrested people, too. The Federal Bureau of Investigation maintains a national database of profiles submitted by laboratories across the country.A few years ago, officials came up with a new way to use DNA profiles in forensic identification. Ordinary searches require an exact match between DNA found at a crime scene and a forensic DNA profile. A partial match means that the profiled individual should not be considered a suspect. But partial matches create another possibility: the crime scene DNA may .. (shrink)
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  36. Yu Lin & Peter Simons, Dna Sequences From Below: A Nominalist Approach.score: 18.0
    We define DNA sequence by a bottom-up approach, starting with a real sequence from an actual biological sample. By providing axioms for notions of string, substring (...)and strand, we formally define a DNA sequence, and a DNA molecule as composed of two antiparallel strands. We note that a sequence is a kind of group in which each member stands a certain relation to every other. The spatial aspects of a DNA sequence are also described. (shrink)
    No categories
    Translate to English
    | Direct download (2 more)  
     
    My bibliography  
     
    Export citation  
  37. Samuel Schindler (2008). Model, Theory, and Evidence in the Discovery of the DNA Structure. British Journal for the Philosophy of Science 59 (4):619-658.score: 18.0
    In this paper, I discuss the discovery of the DNA structure by Francis Crick and James Watson, which has provoked a large historical literature but has yet (...)
    Direct download (9 more)  
     
    My bibliography  
     
    Export citation  
  38. Matthew Gabriel, Cherisse Boland & Cydne Holt (2010). Beyond the Cold Hit: Measuring the Impact of the National DNA Data Bank on Public Safety at the City and County Level. Journal of Law, Medicine and Ethics 38 (2):396-411.score: 18.0
    Over the past decade, the Combined DNA Index System (CODIS) has increased solvability of violent crimes by linking evidence DNA profiles to known offenders. At present, an (...)
    Direct download (5 more)  
     
    My bibliography  
     
    Export citation  
  39. Rogeer Hoedemaekers & Wim Dekkers (2001). Is There a Unique Moral Status of Human DNA That Prevents Patenting? Kennedy Institute of Ethics Journal 11 (4):359-386.score: 18.0
    : The gene patenting debate, which proved to be a focal point for divergent moral concerns about recent developments in genome research and biotechnology, has revealed that the (...) moral status of DNA is not clear. One of the arguments used to stop undesirable developments was that DNA possesses a unique status, which renders it unfit for patenting. This paper investigates the allegedly unique (moral) status of genetic material and the information it holds from different perspectives. Several properties of DNA prove to be unique. We examine the relevance of these for patentability of genes and conclude that only the unique symbolic meaning of DNA is a relevant factor, which should be taken into account but weighed against other interests involved. (shrink)
    Direct download (6 more)  
     
    My bibliography  
     
    Export citation  
  40. D. R. Rokyta, P. Joyce, S. B. Caudle & H. A. Wichman (2005). An Empirical Test of the Mutational Landscape Model of Adaptation Using a Single-Stranded DNA Virus. Nature Genetics 37 (4):441-444.score: 18.0
    The primary impediment to formulating a general theory for adaptive evolution has been the unknown distribution of fitness effects for new beneficial mutations. By applying extreme value (...)
    Translate to English
    | Direct download  
     
    My bibliography  
     
    Export citation  
  41. Richard vSternberg (2008). DNA Codes and Information: Formal Structures and Relational Causes. Acta Biotheoretica 56 (3).score: 18.0
    Recently the termscodesandinformationas used in the context of molecular biology have been the subject of much discussion. Here I propose that a variety (...)
    Direct download  
     
    My bibliography  
     
    Export citation  
  42. A. Patyn & K. Dierickx (2010). Forensic DNA Databases: Genetic Testing as a Societal Choice. Journal of Medical Ethics 36 (5):319-320.score: 18.0
    In this brief report, the authors argue that while a lot of concerns about forensic DNA databases have been raised using arguments from biomedical ethics, these databases (...)
    Direct download (6 more)  
     
    My bibliography  
     
    Export citation  
  43. Holly K. Fernandez (2005). Genetic Privacy, Abandonment, and DNA Dragnets: Is Fourth Amendment Jurisprudence Adequate? Hastings Center Report 35 (1):21-23.score: 18.0
    : Forensic DNA testing threatens American civil liberties.
    Direct download (5 more)  
     
    My bibliography  
     
    Export citation  
  44. James A. Marcum (2007). Experimental Series and the Justification of Temin's DNA Provirus Hypothesis. Synthese 154 (2):259 - 292.score: 18.0
    A notion of experimental series is developed, in which experiments or experimental sets are connected through experimental suggestions arising from previous experimental outcomes. To that end, the (...)
    No categories
    Direct download (5 more)  
     
    My bibliography  
     
    Export citation  
  45. Robersy Sánchez & Ricardo Grau (2006). A Novel Algebraic Structure of the Genetic Code Over the Galois Field of Four DNA Bases. Acta Biotheoretica 54 (1).score: 18.0
    A novel algebraic structure of the genetic code is proposed. Here, the principal partitions of the genetic code table were obtained as equivalent classes of quotient spaces (...)
    Direct download  
     
    My bibliography  
     
    Export citation  
  46. Rosine Chandebois & Jacob Faber (1987). From DNA Transcription to Visible Structure: What the Development of Multicellular Animals Teaches Us. Acta Biotheoretica 36 (2).score: 18.0
    This article is concerned with the problem of the relation between the genetic information contained in the DNA and the emergence of visible structure in multicellular animals. (...)
    No categories
    Direct download  
     
    My bibliography  
     
    Export citation  
  47. E. Suarez (2001). Satellite-DNa: A Case-Study for the Evolution of Experimental Techniques. Studies in History and Philosophy of Science Part C 32 (1):31-57.score: 18.0
    The paper tries to show that an evolutionary perspective helps us to address what is called the adaptation problem, that is, the remarkable coherence, and seemingly successful (...)span> techniques-as a special type amongst evolving scientific practices-is a condition for a better understanding and, ultimately, an explanation of how adaptation among the heterogeneous elements of <span class='Hi'>experimentalspan> knowledge is attained. Some apparently contradictory features of techniques, such as their high context-dependency and their capabilities to reproduce and diversify outside their original contexts, are addressed with the help of the concepts of technical variation and the historical entrenchment of phenomena in techniques. In order to do so, a case-study on the construction of satellite-DNA and the evolution of nucleic acid hybridization, a research project carried out by Roy J. Britten and his colleagues in the 1960s, is presented in detail. This case illustrates the close relationship existing between the evolution of techniques and the stabilization of phenomena in <span class='Hi'>experimentalspan> biology. (shrink)
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
  48. Alexander Pruss, Programs, Bugs, DNA and a Design Argument Alexander R. Pruss May 27, 2004.score: 18.0
    I argue that an examination of the analogy between the notion of a bug and that of a genetic defect supports an analogy not just between a (...)
    No categories
     
    My bibliography  
     
    Export citation  
  49. W. Henn (1999). Genetic Screening with the DNA Chip: a New Pandora's Box? Journal of Medical Ethics 25 (2):200-203.score: 18.0
    The ethically controversial option of genetic population screening used to be restricted to a small number of rather rare diseases by methodological limitations which are now about (...)
    Direct download (6 more)  
     
    My bibliography  
     
    Export citation  
  50. Matthew Kopec (2014). A New Use of 'Race': The Evidence and Ethics of Forensic DNA Ancestry Profiling. Journal of Applied Philosophy 31 (1):237-253.score: 18.0
    Recent advances in population genetics have made it possible to infer an individual's ancestral origin with a high degree of reliability, giving rise to the new (...)technology calledDNA Ancestry Profiling’. Bioethicists have raised concerns over using this technology within a forensic context, many of which stem from issues concerning race. In this article, I offer some reasons why we ought to allow forensic scientists to use DNA Ancestry Profiling to infer the race or ethnicity of perpetratorson a particular understanding of race or ethnicityin at least some cases. First, there is reason to think the process will meet our evidential standards in many cases. Second, the technology has serious prospects for improving racial justice. Third, the ethical concerns that have been raised can be addressed. And last, using Forensic DNA Ancestry Profiling to infer race or ethnicity has many benefits over its successor technology known as Molecular Photofitting. I conclude the essay by sketching the empirical work that remains to be done. (shrink)
    Direct download (4 more)  
     
    My bibliography  
     
    Export citation  
1 — 50 / 923