According to inferential role semantics (IRS), for any given expression to possess a particular meaning one must be disposed to make or, alternatively, acknowledge as correct certain inferential transitions involving it. As Williamson points out, pejoratives such as ‘Boche’ seem to provide a counter-example to IRS. Many speakers are neither disposed to use such expressions nor consider it proper to do so. But it does not follow, as IRS appears to entail, that such speakers do not understand pejoratives or that (...) they lack meaning. In this paper, I examine recent responses to this problem by Boghossian and Brandom and argue that their proposed construal of the kind of inferential rules governing a pejorative such as ‘Boche’ is to be ruled out on the grounds that it is non-conservative. I defend the appeal to conservatism in this instance against criticism and, in doing so, propose an alternative approach to pejoratives on behalf of IRS that resolves the problem Williamson poses. (shrink)
It is common to hear talk of the aim of belief and to find philosophers appealing to that aim for numerous explanatory purposes. What belief's aim explains depends, of course, on what that aim is. Many hold that it is somehow related to truth, but there are various ways in which one might specify belief's aim using the notion of truth. In this article, by considering whether they can account for belief's standard of correctness and the epistemic norms governing belief, (...) I argue against certain prominent specifications of belief's aim given in terms of truth, and advance a neglected alternative. (shrink)
According to Normativism, linguistic meaning is intrinsically normative (I shall explore what this amounts to below). One, though not the only, reason for Normativism’s importance is that it bears on the prospects of providing an account of meaning in the terms available to the natural sciences. In turn, since linguistic behaviour is inextricably bound up with both non linguistic behaviour and the psychological attitudes informing it, Normativism might (if true) pose a serious challenge to the project of accommodating creatures such (...) as ourselves within the worldview the natural sciences afford. In this paper, I shall not focus on such heady themes but rather on the prior issue of whether or not one should accept Normativism. Though certainly in circulation beforehand, it is fair to say that Saul Kripke’s (1982) was largely responsible for bringing the thesis to the philosophical forefront.1 In the years following its publication, Normativism looked close to achieving the status of orthodoxy. At one stage, Crispin Wright felt able to remark assuredly that the view ‘strike[s] most people now as a harmless platitude’ (1993: 247).2 In recent years. (shrink)
That truth provides the standard for believing appears to be a platitude, one which dovetails with the idea that in some sense belief aims only at the truth. In recent years, however, an increasing number of prominent philosophers have suggested that knowledge provides the standard for believing, and so that belief aims only at knowledge. In this paper, I examine the considerations which have been put forward in support of this suggestion, considerations relating to lottery beliefs, Moorean beliefs, the criticism (...) and defence of belief, and the value of knowledge. I argue that those considerations do not give us reason to give up the truth view in favour of the knowledge view and, moreover, that reflection on those considerations gives us some reason to reject the knowledge view. Thus, I conclude, we can continue to the take the apparent platitude at face value. (shrink)
Wittgenstein famously remarks that ‘the meaning of a word is its use’ (PI §43). Whether or not one views this as gesturing at a ‘theory’ of meaning, or instead as aiming primarily at dissuading us from certain misconceptions of language that are a source of puzzlement, it is clear that Wittgenstein held that for certain purposes the meaning of an expression could profitably be characterised as its use. Throughout his later writings, however, Wittgenstein’s appeal to the notion of use pulls (...) in two directions. In several places, Wittgenstein seems to connect the notion of an expression’s meaning with that of use in the sense of usage or practice. More specifically, he suggests that for an expression to possess meaning is for there to be a practice of employing it according to certain rules. ‘That’, he tells us, ‘is why there exists a correspondence between the concepts “rule” and “meaning”’ (OC §62; cf. PG 68; PO 51; RFM VI §28; VW 103). Indeed, Wittgenstein goes so far as to say, ‘The rule-governed nature of our languages permeates our life’ (RC §303). Call the view that the meaning of an expression is determined by a general principle governing its use, rulism. (shrink)
Many philosophers hold that a general norm of truth governs the attitude of believing. In a recent and influential discussion, Krister Bykvist and Anandi Hattiangadi raise a number of serious objections to this view. In this paper, I concede that Bykvist and Hattiangadi's criticisms might be effective against the formulation of the norm of truth that they consider, but suggest that an alternative is available. After outlining that alternative, I argue that it is not vulnerable to objections parallel to those (...) Bykvist and Hattiangadi advance, although it might initially appear to be. In closing, I consider what bearing the preceding discussion has on important questions concerning the natures of believing and of truth. (shrink)
Meaning, according to a significant number of philosophers, is an intrinsically normative notion.1 For this reason, it is suggested, meaning is not conducive to a naturalistic explanation. In this paper, I shall not address whether this is indeed so. Nor shall I present arguments in support of the normativity thesis (see Glock 2005; Kripke 1982). Instead, I shall examine and respond to two forceful objections recently (and independently) raised against it by Boghossian (2005), Hattiangadi (2006) and Miller (2006). Although I (...) shall argue that the objections are unsuccessful, they are worth attending to, not only because the normativity thesis is so widely accepted and is thought to have such ramifications but, most importantly, because doing so offers the opportunity to help clarify how it is to be understood. (shrink)
Abstract: According to deflationism, grasp of the concept of truth consists in nothing more than a disposition to accept a priori (non-paradoxical) instances of the schema:(DS) It is true that p if and only if p.According to contextualism, the same expression with the same meaning might, on different occasions of use, express different propositions bearing different truth-conditions (where this does not result from indexicality and the like). On this view, what is expressed in an utterance depends in a non-negligible way (...) on the circumstances. Charles Travis claims that contextualism shows that ‘deflationism is a mistake’, that truth is a more substantive notion than deflationism allows. In this paper, I examine Travis's arguments in support of this ‘inflationary’ claim and argue that they are unsuccessful. (shrink)
The dictum that meaning is use, that for a word to have a meaning is for it to have a use, is typically presented as placing emphasis on the public nature of linguistic activity, as appropriately situating the notion of meaning in its characteristic context of communication, and more generally as dissuading us from a Cartesian conception of subjects as essentially cut off from one another in private realms. According to its proponents, the appeal to use promises to de-mystify meaning (...) by suitably re-connecting talk of meaning with the familiar and concrete linguistic practices into which we are naturally habituated. Since its first airing, the claim that meaning is use has gained considerable currency. While perhaps not as popular as it once was, it is fair to say that, in one form or another, it is accepted by many prominent philosophers. Indeed, Brian Loar claims that contemporary ‘theory of meaning is divided into two: truth theories, and use theories’ (2006: 85; cf. Borg 2004: 4).2 It seems, then, that the The use of ‘use’ ‘Homeric struggle’ Peter Strawson famously identified battles on (2004: 132). (shrink)
Semantic generalists and semantic particularists disagree over the role of rules or principles in linguistic competence and in the determination of linguistic meaning, and hence over the importance of the notions of a rule or of a principle in philosophical accounts of language. In this paper, I have argued that the particularist’s case against generalism is far from decisive and that by moderating the claims she makes on behalf of her thesis the generalist can accommodate many of the considerations that (...) the particularist cites in support of her position. (shrink)
Knowledge seems to be a good thing, or at least better than epistemic states that fall short of it, such as true belief. Understanding too seems to be a good thing, perhaps better even than knowledge. In a number of recent publications, Duncan Pritchard tries to account for the value of understanding by claiming that understanding is a cognitive achievement and that achievements in general are valuable. In this paper, I argue that coming to understand something need not be an (...) achievement, and so Pritchard's explanation of understanding's value fails. Next, I point out that Pritchard's is just one of many attempts to account for the value of an epistemic state – whether it be understanding, knowledge, or whatever – by appeal to the notion of achievement or, more generally, the notion of success because of ability. Tentatively, I offer reasons to be sceptical about the prospects of any such account. (shrink)
A number of prominent philosophers advance the following ideas: (1) Meaning is use. (2) Meaning is an intrinsically normative notion. Call (1) the use thesis, hereafter UT, and (2) the normativity thesis, hereafter NT. They come together in the view that for a linguistic expression to have meaning is for there to be certain proprieties governing its employment.1 These ideas are often associated with a third.
The view that truth is the norm of assertion has fallen out of fashion. The recent trend has been to think that knowledge is the norm of assertion. Objections to the knowledge view proceed almost exclusively by appeal to alleged counterexamples. While it no doubt has a role to play, such a strategy relies on intuitions concerning hypothetical cases, intuitions which might not be shared and which might shift depending on how the relevant cases are fleshed out. In this paper, (...) I reject the knowledge view on principled grounds. More specifically, by appeal to a principle which is motivated independently of the debate over the norms of assertion and which is already accepted by many proponents of the knowledge view, I show the knowledge view to be false while simultaneously accounting for why it might seem to be true. In doing so, I provide a novel defence of the unfashionable truth view. (shrink)
Many philosophers accept that a naturalistic reduction of meaning is in principle impossible, since behavioural regularities or dispositions are consistent with any number of semantic descriptions. One response is to view meaning as primitive. In this paper, I explore Brandom’s alternative, which is to specify behaviour in non-semantic but normative terms. Against Brandom, I argue that a norm specified in non-semantic terms might correspond to any number of semantic norms. Thus, his theory of meaning suffers from the very same kind (...) of problem as its naturalistic competitors. It is not sufficient, I contend, merely that some norms be introduced into one’s account but that they be specified using intensional, semantic notions on a par with that of meaning. In closing, I counter Brandom’s reasons for resisting such a position, the most significant of which is that it leaves philosophers with nothing constructive to say about meaning. (shrink)
Subjects appear to take only evidential considerations to provide reason or justification for believing. That is to say that subjects do not take practical considerations—the kind of considerations which might speak in favour of or justify an action or decision—to speak in favour of or justify believing. This is puzzling; after all, practical considerations often seem far more important than matters of truth and falsity. In this paper, I suggest that one cannot explain this, as many have tried, merely by (...) appeal to the idea that belief aims only at the truth. I appeal instead to the idea that the aim of belief is to provide only practical reasons which might form the basis on which to act and to make decisions, an aim which is in turn dictated by the aim of action. This, I argue, explains why subjects take only evidential considerations to favour of or justify believing. Surprisingly, then, it turns out that it is practical reason itself which demands that there be no practical reasons for belief. (shrink)
In a recent paper, after outlining various distinguishing features of derogatory words, Jennifer Hornsby suggests that the phenomenon raises serious difficulties for inferentialism. Against Hornsby, I claim that derogatory words do not pose any insuperable problems for inferentialism, so long as it is supplemented with apparatus borrowed from Grice and Hare. Moreover, I argue, derogatory expressions pose difficulties for Hornsby's favoured alternative theory of meaning, representationalism, unless it too is conjoined with a similar Grice/Hare mechanism. So, the upshot of the (...) discussion is that, contra Hornsby, focus on derogatory expressions alone does not provide grounds for deciding between competing theories of meaning, but nevertheless serves to highlight important features that any such theory must acknowledge and incorporate. (shrink)
According to inferential role semantics (IRS), for an expression to have a particular meaning or express a certain concept is for subjects to be disposed to make, or to treat as proper, certain inferential transitions involving that expression.1 Such a theory of meaning is holistic, since according to it the meaning or concept any given expression possesses or expresses depends on the inferential relations it stands in to other expressions.
In this paper, I defend against a number of criticisms an account of slurs, according to which the same semantic content is expressed in the use of a slur (e.g. 'chink') as is expressed in the use of its neutral counterpart (e.g. 'Chinese'), while in addition the use of a slur conventionally implicates a negative, derogatory attitude. Along the way, I criticise competing accounts of the semantics and pragmatics of slurs, namely, Hom's 'combinatorial externalism' and Anderson and Lepore's 'prohibitionism'.
According to inferential role semantics (IRS), for an expression to have a particular meaning or express a certain concept is for subjects to be disposed to make, or to treat as proper, certain inferential transitions involving that expression.1 Such a theory of meaning is holistic, since according to it the meaning or concept any given expression possesses or expresses depends on the inferential relations it stands in to other expressions.
The definitive version of this article is published in Philosophical Books 48.3 July 2007 pp. 233-240 by Blackwell Publishing, and is available at www.blackwell-synergy.com.
In this paper, after outlining the methodological role Wittgenstein's appeal to language-games is supposed to play, I examine the picture of language which his discussion of such games and their relations to what Wittgenstein calls forms of life suggests. It is a picture according to which language and its employment are inextricably connected to wider contexts—they are embedded in specific natural and social environments, they are tied to purposive activities serving provincial needs, and caught up in distinctive ways of life (...) which creatures of a certain sort enjoy. In the remainder of the paper, I consider whether Wittgenstein's emphasis on the link between language and the circumstances surrounding its use points in the direction of an influential view widespread in contemporary philosophy of language, namely, semantic contextualism. I examine carefully a number of passages which scholars have appealed to in support of the claim that Wittgenstein advances contextualism and argue that they in fact provide no such support. The connection which Wittgenstein sees between what is expressed in the use of words and the circumstances in which they are used is not the connection the contextualist insists on. (shrink)
It is commonplace to claim that it is good to believe the truth. In this paper, I reject that claim and argue that the considerations which might seem to support it in fact support a quite distinct though superficially similar claim, namely, that it is bad to believe the false. This claim is typically either ignored completely or lumped together with the previous claim, perhaps on the assumption that the two are equivalent, or at least that they stand or fall (...) together. Such assumptions, I argue, are mistaken. While it is not always good to be right, it is always bad to be wrong. This is an interesting and overlooked asymmetry, which calls for further investigation. (shrink)
‘Particularism’ is a meta-ethical theory resulting from a holistic doctrine in the theory of reasons. According to Jonathan Dancy, the foremost contemporary proponent of particularism, ‘a feature that is a reason in favour of an action in one case may be no reason at all in another, or even a reason against’ (2004: 190). From this, Dancy claims, it follows that the ‘possibility of moral thought and judgement does not depend on the provision of a suitable supply of moral principles’ (...) (2004: 7). This doctrine is of significant interest and import in its own right, and accordingly is the subject of considerable critical attention. The concern of this paper, however, is not meta-ethics but semantics. (shrink)
In this paper, I briefly outline the notion of a truth-conditional meaning-theory and introduce two prominent problems it faces. The“extensionality problem” arises because not all correct specifications of truth-conditions are meaning-giving. The “explanatory problem”concerns the extent to which truth-conditional meaning-theories can contribute to the task of clarifying the nature of linguistic meaning.The “principle of humanity” is supposed to resolve both issues simultaneously. I argue that it fails to do so.
In an article published recently in this journal Daniel Hill argues that it is unacceptable that British law allows doctors to refuse to terminate non-emergency pregnancies but not to refuse to refer given that many doctors who are opposed to non-emergency abortion will be opposed also to any action that aids non-emergency abortion, including the action of referral. In this reply, I argue that Hill’s argument fails to describe properly the correct function of the law, which has never been (...) about ensuring people can exercise moral consistency in their behaviours. (shrink)
In his book Wittgenstein on Rules and Private Language (Kripke 1982), Saul Kripke develops a famous argument that purports to show that there are no facts about what we mean by the expressions of our language: ascriptions of meaning, such as “Jones means addition by ‘+’” or “Smith means green by ‘green’”, are according to Kripke’s Wittgenstein neither true nor false. Kripke’s Wittgenstein thus argues for a form of non- factualism about ascriptions of meaning: ascriptions of meaning do not (...) purport to state facts.1 Define semantic realism to be the view that ascriptions of meaning are apt to be assessed in terms of truth and falsity, and are, at least in some instances, true. Semantic realism, thus defined, is a form of cognitivism about semantic judgement, according to which judgements ascribing meaning express beliefs, states apt for assessment in terms of truth and falsity. Kripke’s Wittgenstein thus argues against semantic realism, and in favour of a form of semantic non-cognitivism. However, another form of opposition to semantic realism accepts that semantic judgements express beliefs but asserts that those beliefs are systematically and uniformly false.2 This cognitivist form of opposition to semantic realism is similar to the error-theoretic form of opposition to moral realism mooted by J.L. Mackie in the first chapter of his Ethics: Inventing Right and Wrong (Mackie 1977). In this paper I will investigate whether there is a plausible analogue of Mackie’s “argument from queerness” that can be used to make a case for an error-theory of semantic judgement. In §2 I set out what I take to be Mackie’s argument from queerness against moral realism. In §3 I argue that there is no straightforward and plausible analogue of that argument that would justify an error theory about ascriptions of meaning. In §4 and §5 I defend the argument of §3 against an objection developed in a recent paper by DanielWhiting. (shrink)
This article defends tradition and common sense against a widespread and rarely questioned contemporary philosophical orthodoxy that underpins the entrenched and exorbitant "lingualism" of so much 20th century thought, and leads the way to extreme doctrines like cognitive relativism and eliminative materialism. It also plugs what might otherwise have seemed to be a significant hole in the argument of my Are Theories of Imagery Theories of Imagination? (which I regard as my main positive contribution so far to the understanding of (...) the mind). For a relatively brief overview of the situation in cognitive theory and consciousness studies, as I see it, see A Stimulus to the Imagination. Click here to view the full article: Imagery and the Coherence of Imagination: a Critique of White. Earlier drafts of this article, one entitled "The White Images of Imagery and Imagination: A Critique and an Alternative", were formerly available on the net. Please make any citations to the published version. - N.J.T.T. (shrink)
Machine generated contents note: Introduction Part One. The Spectacular Life of Spider-Man? 1. Does Peter Parker Have a Good Life? Neil Mussett 2. What Price Atonement? Peter Parker and the Infinite Debt Taneli Kukkonen "My Name is Peter Parker": Unmasking the Right and the Good Mark D. White Part Two. Responsibility-Man 4. "With Great Power Comes Great Responsibility": Spider-Man, Christian Ethics, and the Problem of Evil Adam Barkman 5. Does Great Power Bring Great Responsibility? Spider-Man and the Good Samaritan J. (...) Keeping 6. With Great Power Comes Great Culpability: How Blameworthy is Spider-Man for Uncle Ben's Death? Philip Tallon Part Three. Spider-Sense and the Self 7. Why is My Spider-Sense Tingling? Andrew Terjesen 8. Red or Black: Perception, Identity and Self Meaghan P. Godwin 9. With Great Power: Heroism, Villainy, and Bodily Transformation Mark K. Spencer Part Four. Arachnids "R" Us: Technology and the Human, All Too Human 10. Transhumanism: Or, Is It Right to Make a Spider-Man? Ron Novy 11. Maximum Clonage: What the Clone Saga Can Teach Us About Human Cloning Jason Southworth and John Timm Part Five. Your Friendly Neighborhood Spider-Man 12. Justice versus Romantic Love: Can Spider-Man Champion Justice and Be with Mary Jane at the Same Time? Charles Taliaferro and Tricia Little 13. Friendship, and Being Spider-Man Tony Spanakos 14. Spidey's Tangled Web of Obligations: Fighting Friends and Dependents Gone Bad Christopher Robichaud Part Six. The Amazing Speaking Spider: Jokes, Stories, and the Choices We Make 15. The Quipslinger: The Morality of Spider-Man's Jokes Daniel P. Malloy 16. The Sound and Fury Behind "One More Day" Marks D. White 17. Spider-Man and the Importance of Getting Your Story Straight Jonathan J. Sanford Contributors Index . (shrink)
Bioethics at the Movies explores the ways in which popular films engage basic bioethical concepts and concerns. Twenty philosophically grounded essays use cinematic tools such as character and plot development, scene-setting, and narrative-framing to demonstrate a range of principles and topics in contemporary medical ethics. The first section plumbs popular and bioethical thought on birth, abortion, genetic selection, and personhood through several films, including The Cider House Rules, Citizen Ruth, Gattaca, and I, Robot. In the second section, the contributors examine (...) medical practice and troubling questions about the quality and commodification of life by way of Dirty Pretty Things, Eternal Sunshine of the Spotless Mind, and other movies. The third section's essays use Million Dollar Baby, Critical Care, Big Fish, and Soylent Green to show how the medical profession and society at large view issues related to aging, death, and dying. A final section makes use of Extreme Measures and select Spanish and Japanese films to discuss two foundational matters in bioethics: the role of theories and principles in medicine and the importance of cultural context in devising care. Structured to mirror bioethics and cinema classes, this innovative work includes end-of-chapter questions for further consideration and contributions from scholars from the United States, Canada, the United Kingdom, Israel, Spain, and Australia. Contributors: Robert Arp, Ph.D., Michael C. Brannigan, Ph.D., Matthew Burstein, Ph.D., Antonio Casado da Rocha, Ph.D., Stephen Coleman, Ph.D., Jason T. Eberl, Ph.D., Paul J. Ford, Ph.D., Helen Frowe, M.A., Colin Gavaghan, Ph.D., Richard Hanley, Ph.D., Nancy Hansen, Ph.D., Al-Yasha Ilhaam, Ph.D., Troy Jollimore, Ph.D., Amy Kind, Ph.D., Zana Marie Lutfiyya, Ph.D., Terrance McConnell, Ph.D., Andy Miah, Ph.D., Nathan Norbis, Ph.D., Kenneth Richman, Ph.D., Karen D. Schwartz, LL.B., M.A., Sandra Shapshay, Ph.D., Daniel Sperling, LL.M., S.J.D., Becky Cox White, R.N., Ph.D., Clark Wolf, Ph.D. (shrink)
In contrast to many of his contemporaries, A. J. Ayer was an analytic philosopher who had sustained throughout his career some interest in developments in the work of his ‘continental’ peers. Ayer, who spoke French, held friendships with some important Parisian intellectuals, such as Camus, Bataille, Wahl and Merleau-Ponty. This paper examines the circumstances of a meeting between Ayer, Merleau-Ponty, Wahl, Ambrosino and Bataille, which took place in 1951 at some Parisian bar. The question under discussion during this meeting was (...) whether the sun existed before humans did, over which the various philosophers disagreed. This disagreement is tangled with a variety of issues, such as Ayer’s critique of Heidegger and Sartre (inherited from Carnap), Ayer’s response to Merleau-Ponty’s critique of empiricism, and Bataille’s response to Sartre’s critique of his notion of ‘unknowing’, which uncannily resembles Ayer’s critique of Sartre. 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Thomas Elsaesser claims the late Haneke as a director of ‘mind-game’ films, but his diagnosis of the appeal of such films fails to account for The White Ribbon . In this paper, I draw on the theory of radical interpretation developed by American philosopher Donald Davidson to uncover the film’s power. I argue that the focus on charity in Davidson’s account of the conditions under which an interpreter is able to find a foreign community intelligible illuminates the exquisite discomfort the (...) spectator experiences as she begins to understand the disturbed community that the film portrays. In addition, the film exposes that Davidson’s transcendental argument that language is a condition of mindedness ought to be extended along emotional and moral dimensions. We should not only hold that every rational mind is a language-user, but that every rational mind is an appropriate language-user, so as to account for minds that have true, justified beliefs but which are, nevertheless, disturbed. (shrink)
This offering in Routledge's acclaimed History of Philosophy series completes the acclaimed 10-volume collection. This work explores the schools of thought that developed in the wake of Platonism through the time of Augustine. The 11 separately authored in-depth articles include: Aristotle the scientist-- David Furley, Princeton University; Aristotle: logic and metaphysics-- Alan Code, Ohio State University; Aristotle: aesthetics and philosophy of mind -- David Gallop, Trent University, Ontario; Aristotle: ethics and politics-- Stephen White, University of Texas at Austin; The peripatetic (...) school-- Robert Sharples, University College, London; Hellenistic science and mathematics-- Alan C. Bowen, Institute for Research in Classical Philosophy and Science, New Jersey; Epicureanism-- Philip Mitsis, Cornell University; Stoicism-- Brad Inwood, University of Toronto; Ancient skepticism-- Michael Frede, Keble College, Oxford; Neo-Platonism-- Eyjdfur Kjalar Emilsson, University of Iceland; Augustine-- G.J.P. O'Daly, University College London. Order the entire Routledge History of Philosophy series and save 10% off each volume! (shrink)
Carbon monoxide (CO) intoxication leads to acute and chronic neurological deficits, but little is known about the specific noxious mechanisms. 1 H magnetic resonance spectroscopy (MRS) may allow insight into the pathophysiology of CO poisoning by monitoring neurochemical disturbances, yet only limited information is available to date on the use of this protocol in determining the neurological effects of CO poisoning. To further examine the short-term and long-term effects of CO on the (...) central nervous system, we have studied seven patients with CO poisoning assessed by gray and white matter MRS, magnetic resonance imaging (MRI) and neuropsychological testing. Five patients suffered from acute high-dose CO intoxication and were in coma for 1–6 days. In these patients, MRI revealed hyperintensities of the white matter and globus pallidus and also showed increased choline (Cho) and decreased N -acetyl aspartate (NAA) ratios to creatine (Cr), predominantly in the white matter. Lactate peaks were detected in two patients during the early phase of high-dose CO poisoning. Two patients with chronic low-dose CO exposure and without loss of consciousness had normal MRI and MRS scans. On follow-up. five of our seven patients had long-lasting intellectual impairment, including one individual with low-dose CO exposure. The MRS results showed persisting biochemical alterations despite the MRI scan showing normalization of morphological changes. In conclusion, the MRS was normal in patients suffering from chronic low-dose CO exposure; in contrast, patients with high-dose exposure showed abnormal gray and white matter levels of NAA/Cr, Cho/Cr and lactate, as detected by 1 H MRS, suggesting disturbances of neuronal function, membrane metabolism and anaerobic energy metabolism, respectively. Early increases in Cho/Cr and decreases of NAA/Cr may be related to a poor long-term outcome, but confirmation by future studies is needed. (shrink)
With over 150 alphabetically arranged entries about key scientists, concepts, discoveries, technological innovations, and learned institutions, the Oxford Guide to Physics and Astronomy traces the history of physics and astronomy from the Renaissance to the present. For students, teachers, historians, scientists, and readers of popular science books such as Galileo's Daughter, this guide deciphers the methods and philosophies of physics and astronomy as well as the historical periods from which they emerged. Meant to serve the lay reader and the professional (...) alike, this book can be turned to for the answer to how scientists learned to measure the speed of light, or consulted for neat, careful summaries of topics as complicated as quantum field theory and as vast as the universe. The entries, each written by a noted scholar and edited by J. L. Heilbron, Professor of History and Vice Chancellor, Emeritus, University of California, Berkeley, reflect the most up-to-date research and discuss the applications of the scientific disciplines to the wider world of religion, law, war, art and literature. No other source on these two branches of science is as informative or as inviting. Thoroughly cross-referenced and accented by dozens of black and white illustrations, the Oxford Guide to Physics and Astronomy is the source to turn to for anyone looking for a quick explanation of alchemy, x-rays and any type of matter or energy in between. (shrink)
