Life appears to be a natural property of matter, but the problem of its origin only arose after early scientists refuted continuous spontaneous generation. There is no chance of life arising ‘all at once’, we need the standard scientific incremental explanation with large numbers of small steps, an approach used in both physical and evolutionary sciences. The necessity for considering both theoretical and experimental approaches is emphasized. After describing basic principles that are available (including the Darwin-Eigen cycle), (...) the search for origins is considered under four main themes. These are the RNA-world hypothesis; potential intermediates between an RNA-world and a modern world via the evolution of protein synthesis and then of DNA; possible alternatives to an RNA-world; and finally the earliest stages from the simple prebiotic systems to RNA. The triplicase/proto-ribosome theory for the origin of the ribosome is discussed where triples of nucleotides are added to a replicating RNA, with the origin of a triplet code well-before protein synthesis begins. The length of the code is suggested to arise from the early development of a ratchet mechanism that overcomes the problem of continued processivity of an RNA-based RNA-polymerase. It is probable that there were precursor stages to RNA with simpler sugars, or just two nucleotides, but we do not yet know of any better alternatives to RNA that were likely to arise naturally. For prebiotic stages (before RNA) a flow-reactor model is suggested to solve metabolism, energy gradients, and compartmentation simultaneously – thus the intense interest in some form of flow reactor. If an autocatalytic cycle could arise in such a system we would be major steps ahead. The most likely physical conditions for the origin of life require further clarification and it is still unclear whether the origin of life is more of an entropy (information) problem (and therefore high temperatures would be detrimental), rather than a kinetic problem (where high temperatures may be advantageous). (shrink)

Modern scientific theories of emotional behavior, almost without exception, trace their origin to Charles Darwin, and his publications On the Origin of Species (1859) and The Expression of the Emotions in Man and Animals (1872). The most famous evolutionary dilemma Darwin acknowledged as a challenge to his theory of natural selection was the incomplete sub Cambrian fossil record. However, Darwin struggled with two other rarely referenced theoretical and scientific dilemmas that confounded his theories about emotional behavior. These (...) included (1) the origin of social instincts (e.g., altruism, empathy, reciprocity and cooperation) and the reasons for their conservation in evolution and (2) the peripheral control of heart rate vis-a-vis emotional behavior outside of consciousness. Darwin acknowledged that social instincts are critical to the survival of some species, but had difficulty aligning them with his theory of natural selection in humans. Darwin eventually proposed that heart rate and emotions are controlled via one’s intellect and cortical mechanisms, and that instinctive behavior is genetically-programmed and inherited. Despite ongoing efforts, these two theoretical dilemmas are debated to this day. Simple testable hypotheses have yet to emerge for the biological mechanisms underlying instinctive behavior or the way heart rate is controlled in infants. In this paper, we review attempts to resolve ¬these issues over the past 160 years. We posit that research and theories that supported Darwin’s individualistic brain-centric and genetic model have become an “orthodox” Western view of emotional behavior, one that produced the prevailing behavioral construct of attachment as developed by John Bowlby. We trace research and theories that challenged this orthodoxy at various times, and show how these challenges were repeatedly overlooked, rejected, or misinterpreted. We review two new testable theories, emotional connection theory and calming cycle theory, which we argue resolve the two dilemmas We show emerging scientific evidence from physiology and a wide variety of other fields, as well from clinical trials among prematurely born infants, that supports the two theories. Clinical implications of the new theories and possible new ways to assess risk and intervene in emotional, behavioral and developmental disorders are discussed. (shrink)

One of science's greatest intellects examines how people and animals display fear, anger, and pleasure. Darwin based this 1872 study on his personal observations, which anticipated later findings in neuroscience. Abounding in anecdotes and literary quotations, the book is illustrated with 21 figures and seven photographic plates. Its direct approach, accessible to professionals and amateurs alike, continues to inspire and inform modern research in psychology.

The publication of Darwin's On the Origin of Species in 1859 ignited a public storm he neither wanted nor enjoyed. Having offered his book as a contribution to science, Darwin discovered to his dismay that it was received as an affront by many scientists and as a sacrilege by clergy and Christian citizens. To answer the criticism that his theory was a theory only, and a wild one at that, he published two volumes in 1868 to demonstrate that (...) evolution was obvious to anyone who cared to look at a bull in a pasture or a dog on a hearth. In response to those who insisted that species were distinct since creation, Darwin pointed to breeders of pigs and pigeons. In reply to those who protested that human intervention is one thing and natural selection another, he argued, "If organic beings had not possessed an inherent tendency to vary, man could have done nothing." To counter those who scorned his descriptions of species in exotic places, he submitted local evidence of cabbages and cauliflower. Based on a wide array of sources, from ancient pictographs to Polish roosters, from skins and from skeletons, from scientific journals and breeding manuals, Darwin assembled a mass of proof--and a hypothesis about species reversion that risked his reputation anew. The Variation of Animals and Plants under Domestication is a two-volume compilation of his thorough and intensive research and the revolutionary conclusions that resulted. The first portion of his work is dedicated to a meticulous analysis of various aspects of plant and animal life, including an inventory of varieties and their physical and behavioral characteristics, investigation of the impact of a species' surrounding environment and the role that both natural and forced changes in this environment have had. Darwin then turns to a richly detailed discussion of the roles of inheritance and crossing in the development of species. A wealth of illustrations further support and enhance his findings. This fascinating, invaluable, and courageous undertaking eventually formed the foundation for our current understanding of evolution. "In science as in politics the victors tend to write the history books. As a result, the record of the past is edited, intentionally or unintentionally, so that it focuses mainly on the precursors of contemporary orthodoxy. Such a focus may accurately represent the genealogy of modern ideas, but it almost inevitably misrepresents the historical experience of their progenitors... Even the powerful, persuasive, and ultimately triumphant theory of evolution by natural selection required not only defense, but repeated buttressing and revision. Variation showed Darwin hard at work on this rearguard action, using the materials he had at hand... His information was gleaned from the observations of fanciers, breeders, and amateur naturalists, as well as from the treatises of those on the cutting edge of zoology and botany. As hindsight narrows the historical spotlight, it imposes its own sense of hierarchy on the preoccupations of the past. But Darwin was interested in all of these topics, valued all of these sources, and belonged, to a greater or lesser extent, to all of these communities."--from the Introduction. (shrink)

Perhaps the most readable and accessible of the great works of scientific imagination, The Origin of Species sold out on the day it was published in 1859. Theologians quickly labeled Charles Darwin the most dangerous man in England, and, as the Saturday Review noted, the uproar over the book quickly "passed beyond the bounds of the study and lecture-room into the drawing-room and the public street." Yet, after reading it, Darwin's friend and colleague T. H. Huxley had a (...) different reaction: "How extremely stupid not to have thought of that." Based largely on Darwin's experience as a naturalist while on a five-year voyage aboard H.M.S. Beagle, The Origin of Species set forth a theory of evolution and natural selection that challenged contemporary beliefs about divine providence and the immutability of species. A landmark contribution to philosophical and scientific thought, this edition also includes an introductory historical sketch and a glossary Darwin later added to the original text. Charles Darwin grew up considered, by his own account, "a very ordinary boy, rather below the common standard of intellect." A quirk of fate kept him from the career his father had deemed appropriate--that of a country parson--when a botanist recommended Darwin for an appointment as a naturalist aboard H.M.S. Beagle from 1831 to 1836. Darwin is also the author of the five-volume work Zoology of the Voyage of the Beagle (1839) and The Descent of Man (1871). (shrink)

Familiarity with Charles Darwin's treatise on evolution is essential to every well-educated individual. One of the most important books ever published--and a continuing source of controversy, a century and a half later--this classic of science is reproduced in a facsimile of the critically acclaimed first edition.

For nearly five years, from Dec. 27, 1831, until Oct. 2, 1836, I served as naturalist aboard the H.M.S. Beagle, exploring. During that voyage I was much amazed by how the various types of organisms were distributed around South America, and how the animals and plants presently living on that continent are related to those found only as fossils in the geological record elsewhere. These facts, as will be seen in later chapters, seemed to me to throw some light on (...) the origin of species-that "mystery of mysteries," as it has been called by one of our greatest scientists, John Herschel. After I returned home, it occurred to me in 1837 that I might be able to help address this great question by patiently accumulating and reflecting on all sorts of facts that might have any bearing on it. Finally, after five years of work, I allowed myself to speculate on the subject and wrote up some brief notes. I enlarged these in 1844 into a sketch of the conclusions that seemed to be most probable from the evidence I had collected. Over the subsequent 15 years I have steadily pursued the same object: trying to understand how new species come about. I hope you will excuse me for entering these personal details of my work, as I give them only to show that I have not been hasty in coming to a decision. (shrink)

Contains conversations that provide an insight into the mind of one of the most original psychoanalysts - Michael Eigen. This book covers various subjects, spread over a wide range of interest, which Michael Eigen talks about. It aims at helping readers to enter the ideas of Eigen more directly than they could have via Eigen's books and papers.

A treasure trove of illuminating and entertaining quotations from the legendary naturalist Here is Charles Darwin in his own words—the naturalist, traveler, scientific thinker, and controversial author of On the Origin of Species, the book that shook the Victorian world. Featuring hundreds of quotations carefully selected by world-renowned Darwin biographer Janet Browne, The Quotable Darwin draws from Darwin’s writings, letters to friends and family, autobiographical reminiscences, and private scientific notebooks. It offers a multifaceted portrait that takes (...) readers through his youth, the famous voyage of the Beagle, the development of his thoughts about evolution, his gradual loss of religious faith, and the time spent turning his ideas into a well-articulated theory about the natural origin of all living beings—a theory that dangerously included the origin of humans. The Quotable Darwin also includes many of the key responses to Darwin’s ideas from figures across the social spectrum, scientists and nonscientists alike—and criticism too. We see Darwin as an innovative botanist and geologist, an affectionate husband and father, and a lively correspondent who once told his cousin that he liked to play billiards because “it drives the horrid species out of my head.” This book gives us an intimate look at Darwin at work, at home, as a public figure, and on his travels. Complete with a chronology of Darwin’s life by Browne, The Quotable Darwin provides an engagingly fresh perspective on a remarkable man who was always thinking deeply about the natural world. (shrink)

For nearly five years, from Dec. 27, 1831, until Oct. 2, 1836, I served as naturalist aboard the H.M.S. Beagle, exploring. During that voyage I was much amazed by how the various types of organisms were distributed around South America, and how the animals and plants presently living on that continent are related to those found only as fossils in the geological record elsewhere. These facts, as will be seen in later chapters, seemed to me to throw some light on (...) the origin of species-that "mystery of mysteries," as it has been called by one of our greatest scientists, John Herschel. After I returned home, it occurred to me in 1837 that I might be able to help address this great question by patiently accumulating and reflecting on all sorts of facts that might have any bearing on it. Finally, after five years of work, I allowed myself to speculate on the subject and wrote up some brief notes. I enlarged these in 1844 into a sketch of the conclusions that seemed to be most probable from the evidence I had collected. Over the subsequent 15 years I have steadily pursued the same object: trying to understand how new species come about. I hope you will excuse me for entering these personal details of my work, as I give them only to show that I have not been hasty in coming to a decision. (shrink)

This book explores ways we make contact with the depths in ourselves and each other. We are deeply moved by contact we make with life, yet also puzzled by a need to break or lose contact, and often suffer wounds by failure of contact to be born. Our sense of contact is tenacious and fragile, subject to deformations, plagued with a sense of jeopardy. Chapters focus on ways we make-and-break contact in the wounded aloneness of addiction, the wounded beauty of (...) psychosis, the importance of not knowing and wordlessness, ways we transmit emotions, the need to start over, and harm we cause by trying to get rid of and misuse tendencies that are part of our makeup. Our contact with life, ourselves, each other is challenged. And through it all, we have need for deep contact, contact with the depths, fulfilling and suspenseful. Contact we never stop growing into, part of the mystery, care and love of everyday life. (shrink)

Using game theory and examples of actual games people play, Nobel laureate Manfred Eigen and Ruthild Winkler show how the elements of chance and rules underlie ...

This book presents a vivid argument for the almost lost idea of a unity of all natural sciences. It starts with the "strange" physics of matter, including particle physics, atomic and quantum mechanics, cosmology, relativity and their consequences (Chapter 1), and it continues by describing the properties of material systems that are best understood by statistical and phase-space concepts (Chapter 2). These lead to entropy and to the classical picture of quantitative information, initially devoid of value and meaning (Chapter 3). (...) Finally, "information space" and dynamics within it are introduced as a basis for semantics (Chapter 4), leading to an exploration of life and thought as new problems in physics (Chapter 5). Dynamic equations - again of a strange (but very general) nature - bring about the complex familiarity of the world we live in. Surprising new results in the life sciences open our eyes to the richness of physical thought, and they show us what can and what cannot be explained by a Darwinian approach. The abstract physical approach is applicable to the origins of life, of meaningful information and even of our universe. [T]itle presents a vivid argument for a unity of all natural sciences. This unity engenders the 'complex familiarity' of the world in which we live and which can be described in 'strangely simple' theoretical terms, leading to new insights into the mysterious phenomenon of life. (shrink)

The present edition provides a detailed and accessible discussion ofhis theories and adds an account of the immediate responses to the book on publication.

This book explores psychoanalytic faith and, more generally, the role of faith in the therapeutic process. In his earlier work, Eigen distinguished faith from beliefs used to organize it, the latter at once bringing people together and creating violent oppositions - belief as a defense against faith. In this new work, Eigen dives into faith experience itself and shares what he finds.Faith spans many dimensions. The opening chapters focus on variations of faith, beginning with nature, sleep, beauty, goodness, (...) the opening-closing of the human face, and the paradox of the growth of faith through pain and shattering. Accounts of faith in the author's life lead to creative readings of Winnicott followed by meditations on evil. A chapter is devoted to teaching and learning Bion, who called faith the psychoanalytic attitude (or called the psychoanalytic attitude Faith). Another chapter discusses variants of everyday mystical participation and a climactic moment in the Zohar, a principal part of the Kabbalah. The book ends with interviews involving the author's development as a psychotherapist-psychoanalyst, his views on mental health and society today, followed by a note on faith-work. (shrink)

Wilfred Bion once said, "I use the Kabbalah as a framework for psychoanalysis." Both are preoccupied with catastrophe and faith, infinity and intensity of experience, shatter and growth of being that supports dimensions which sensitivity opens. Both are preoccupied with ontological implications of the Unknown and the importance of emotional life. This work is a psychospiritual adventure touching the places Kabbalah and psychoanalysis give something to each other. Michael Eigen uses aspects of Bion, Winnicott, Akivah, Luria and Nachman (and (...) many more) as colours on a palette to open realities for growth of experience. Bion called faith "the psychoanalytic attitude" and Eigen here explores creative, paradoxical, multidimensional aspects of faith. Eigen previously wrote of psychoanalysis as a form of prayer in The Psychoanalytic Mystic. In Kabbalah and Psychoanalysis he writes of creative faith. Sessions as crucibles in which diverse currents of personality mix in new ways, alchemy or soul chemistry perhaps, or simply homage to our embryonic nature which responds to the breath of feeling moment to moment. This book brings out ways that a sense of infinity interweaves with everyday life, at the same time it faces the destructiveness of life and human nature and attempts to work with it. Read these chapters and see where they take you. They are meant as personal support for your own inner work, touching nooks and crannies hungry for touch. (shrink)

Many people seek help because they feel dragged down by a sense of inner deadness that persists in an otherwise full and meaningful life. These individuals who seem filled with emotions somehow remain untouched by even their own inner experiences. This is a deadness that persists in the midst of plenty, a deadness that can cripple their entire life or part of it. This book portrays attempts to fathom psychic deadness, but more important, it shows what is involved in enduring (...) and working with deadness on a day-to-day, session-by-session basis. Often, the therapy relationship becomes a laboratory in which varying states of deadness-aliveness can be tied to what is going on between patient and therapist, as well as in the patient's life. In many cases, according to Eigen, the emotional tone of the therapy can be the most important element. Patient and therapist work to discover what the patient is looking for, that is, the precise combination of psychic nutrients, responses, attitudes, and tones required for a given individual, or even a given moment, so that a person can begin to open, and the deadness can lift. (shrink)

Understanding the psychodynamics of madness is essential to the therapy of most patients, including those who are not diagnosed as mad in the literal sense. This volume draws on Freud, Jung, recent object relation and self psychologies, and, particularly, the work of Winnicott, Bion and Elkin. It describes and critiques the basic ideas on the dynamics of psychoses and provides a framework for interpretation.

In The Origin of Species (1859) Darwin challenged many of the most deeply-held beliefs of the Western world. Arguing for a material, not divine, origin of species, he showed that new species are achieved by "natural selection." The Origin communicates the enthusiasm of original thinking in an open, descriptive style, and Darwin's emphasis on the value of diversity speaks more strongly now than ever. As well as a stimulating introduction and detailed notes, this edition offers a register of (...) the many writers referred to by Darwin in the text. (shrink)

t. 1. Puteshestvie naturalista vokrug sveta.--t. 2. Zoologicheskie raboty. Dozhdevye chervi. Geologicheskie raboty.--t. 3. Proiskhozhdenie vidov putem estestvennogo otbora.--t. 4. Izmenenii︠a︡ domashnikh zhivotnykh i kulʹturnykh rasteniĭ.-- t. 6. Opylenie orkhideĭ nasekomymi. Perekrestnoe opylenie i samoopylenie.--t. 7. Razlichnye formy t︠s︡vetov. Nasekomoi︠a︡dnye rastenii︠a︡.-- t. 9. Zapisnye knizhki. Dnevniki. Vospominanii︠a︡. Zhiznʹ Ėrazma Darvina.

... Difficulty of distinguishing between Varieties and Species — Origin of Domestic ... and Origin— Principle of Selection anciently followed, its Effects— ...

Primary aloneness -- Incommunicado core and boundless supporting unknown -- Guilt in an age of psychopathy -- I killed Socrates -- Revenge ethics -- Something wrong -- Emily and M.E. -- Faith and destructiveness.

Darwin discusses why different muscles are brought into action under different emotions and how particular animals have adapted for association with man.

This is a reproduction of Darwin's early essay arguing that species change over time, drafted in 1842, seventeen years before he published 'On the Origin of Species'.

ORIGIN OF SPECIES. INTRODUCTION. When on board HMS 'Beagle,' as naturalist, I was ranch struck with certain facts in the distribution of the organic beings ...

Avtobiohrafii︠a︡ Ch. Darvina (p. [513]-560).

Charles Darwin's On the Origin of Species is unquestionably one of the chief landmarks in biology. The Origin (as it is widely known) was literally only an abstract of the manuscript Darwin had originally intended to complete and publish as the formal presentation of his views on evolution. Compared with the Origin, his original long manuscript work on Natural Selection, which is presented here and made available for the first time in printed form, has more abundant examples and (...) illustrations of Darwin's argument, plus an extensive citation of sources. (shrink)

Illuminates the emergence of race as a central concept in philosophy and the social sciences.

Divided into three parts, this book's purpose, as given in the introduction, is to consider whether or not man is descended from a pre-existing form, his manner ...