Despite general agreement that altered reward sensitivity is involved in attention-deficit/hyperactivity disorder (ADHD), a wide range of different alterations has been proposed. We cite work showing abnormal sensitivity to delay of reward, together with abnormal sensitivity to individual instances of reward. We argue that at the cellular level these behavioural characteristics might indicate that dopamine timing is off in children with ADHD.
Method in Ancient Philosophy brings together fifteen new, specially written essays by leading scholars on a broad subject of central importance. The ancient Greeks recognized that different forms of human activity are guided by different methods of reasoning; examination of how they reasoned, and how they thought about their own reasoning, helps us to see how they came to hold the views they did, and how our own methods of enquiry have developed under their influence. Contributors include Terence Irwin, Patricia (...) Curd, Ian Mueller, Robert Bolton, A.A. Long, Gail Fine, Constance C. Meinwald, Lesley Brown, Gisela Striker, C.D.C. Reeve, Charlotte Witt, Richard Kraut, Sarah Broadie, James Allen, and G.E.R. Lloyd. (shrink)
Using the 1991 police beating of Rodney King as case study, this paper draws on Husserlian phenomenology to establish a coherentist account of knowledge as situated with respect to its concrete circumstances of production (e.g., social, cultural, historical, political). I take as my point of departure Gail Weiss's phenomenological investigation into the jury's assessment of evidence in the "Rodney King incident," and in particular, her interest in Husserl's conception of the "horizon" as a structure of consciousness that mediates what (...) is present in perceptual awareness. Making use of Anthony Steinbock's work on Husserlian phenomenological method — drawn from his extensive study of Husserl's unpublished manuscripts — I develop an epistemological framework that treats knowledge claims as inextricably bound to the horizons of meaning from which they arise, and provides standards of epistemic responsibility pertaining to an agent's "framing" of evidence. (shrink)
The ability of 3- and 4-year-old children to disregard advice from an overtly misleading informant was investigated across five studies (total n = 212). Previous studies have documented limitations in young children's ability to reject misleading advice. This study was designed to test the hypothesis that these limitations are primarily due to an inability to reject specific directions that are provided by others, rather than an inability to respond in a way that is opposite to what has been indicated by (...) a cue. In Studies 1 through 4, a puppet identified as The Big Bad Wolf offered advice to participants about which of two boxes contained a hidden sticker. Regardless of the form the advice took, 3-year olds performed poorly by failing to systematically reject it. However, when participants in Study 5 believed they were responding to a mechanical cue rather than the advice of the Wolf, they were better able to reject misleading advice, and individual differences in performance on the primary task were systematically correlated with measures of executive function. Results are interpreted as providing support for the communicative intent hypothesis, which posits that children find it especially difficult to reject deceptive information that they perceive as being intentionally communicated by others. (shrink)
Research on the ethical, legal, and social implications (ELSI) of human genomics has devoted significant attention to the research ethics issues that arise from genomic science as it moves through the translational process. Given the prominence of these issues in today's debates over the state of research ethics overall, these studies are well positioned to contribute important data, contextual considerations, and policy arguments to the wider research ethics community's deliberations, and ultimately to develop a research ethics that can help guide (...) biomedicine's future. In this essay, we illustrate this thesis through an analytic summary of the research presented at the 2011 ELSI Congress, an international meeting of genomics and society researchers. We identify three pivotal factors currently shaping genomic research, its clinical translation, and its societal implications: (1) the increasingly blurred boundary between research and treatment; (2) uncertainty — that is, the indefinite, indeterminate, and incomplete nature of much genomic information and the challenges that arise from making meaning and use of it; and (3) the role of negotiations between multiple scientific and non-scientific stakeholders in setting the priorities for and direction of biomedical research, as it is increasingly conducted “in the public square.”. (shrink)
Contextualism is an epistemological claim that truth-conditions of knowledge ascribing sentences depend on context in which they are uttered. The discussion concerned with its background and assumptions is predominant in recent epistemology. However, contextualism is known better as the suggested solution for skepticism about the external world. In this paper I present one of the most important contextualist theory which have been proposed in 90's by Keith DeRose. In what follows I outline this proposal's main sources, i.e. i) a relevant (...) alternative theory, ii) Nozick's definition of knowledge and iii) two earlier contextualist ideas made by David Lewis and Gail Stine. Next, I consider some weak aspects of this theory that have been pointed out by critics. (shrink)
A recent story in USA Today about the war in Afghanistan drew a direct parallel to the film Black Hawk Down : When the history of the war is written, the traumatic battle in the mountains around the Shah-e-Kot Valley will be remembered as a testament to heroism: A bloodied, outnumbered band of US servicemen held off a determined al-Qaeda force on frigid rocky terrain at least 8,000 feet above sea level. Call it Black Hawk Down in the snow. (Jonathan (...) Weisman, "Deadliest day for US", USA Today 3/6/02). Why would a reporter (Jonathan Weisman) interrupt his recitation of the facts of the battle, right near the start of his article, to suggest that readers should mimic the judgment of the film? Because the film seems to have a message, not only about history, but about the current US war on terrorism: support our troops, and don�t question a war�s intent or methods. (shrink)