Search results for 'Irreversible brain interventions' (try it on Scholar)

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  1. Frederic Gilbert, Alexander R. Harris & Robert M. I. Kapsa (2012). Efficacy Testing as a Primary Purpose of Phase 1 Clinical Trials: Is It Applicable to First-in-Human Bionics and Optogenetics Trials? AJOB Neuroscience 3 (2):20-22.score: 87.0
    In her article, Pascale Hess raises the issue of whether her proposed model may be extrapolated and applied to clinical research fields other than stem cell-based interventions in the brain (SCBI-B) (Hess 2012). Broadly summarized, Hess’s model suggests prioritizing efficacy over safety in phase 1 trials involving irreversible interventions in the brain, when clinical criteria meet the appropriate population suffering from “degenerative brain diseases” (Hess 2012). Although there is a need to reconsider the traditional (...)
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  2. Nicole A. Vincent (2014). Neurolaw and Direct Brain Interventions. Criminal Law and Philosophy 8 (1):43-50.score: 76.7
    This issue of Criminal Law and Philosophy contains three papers on a topic of increasing importance within the field of “neurolaw”—namely, the implications for criminal law of direct brain intervention based mind altering techniques (DBI’s). To locate these papers’ topic within a broader context, I begin with an overview of some prominent topics in the field of neurolaw, where possible providing some references to relevant literature. The specific questions asked by the three authors, as well as their answers and (...)
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  3. Nicole A. Vincent (2014). Neurolaw and Direct Brain Interventions. Criminal Law and Philosophy 8 (1):43-50.score: 76.7
    This issue of Criminal Law and Philosophy contains three papers on a topic of increasing importance within the field of “neurolaw”—namely, the implications for criminal law of direct brain intervention based mind altering techniques (DBI’s). To locate these papers’ topic within a broader context, I begin with an overview of some prominent topics in the field of neurolaw, where possible providing some references to relevant literature. The specific questions asked by the three authors, as well as their answers and (...)
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  4. Nicole A. Vincent (2014). Restoring Responsibility: Promoting Justice, Therapy and Reform Through Direct Brain Interventions. [REVIEW] Criminal Law and Philosophy 8 (1):21-42.score: 68.0
    Direct brain intervention based mental capacity restoration techniques—for instance, psycho-active drugs—are sometimes used in criminal cases to promote the aims of justice. For instance, they might be used to restore a person’s competence to stand trial in order to assess the degree of their responsibility for what they did, or to restore their competence for punishment so that we can hold them responsible for it. Some also suggest that such interventions might be used for therapy or reform in (...)
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  5. Elizabeth Shaw (2014). Direct Brain Interventions and Responsibility Enhancement. Criminal Law and Philosophy 8 (1):1-20.score: 56.0
    Advances in neuroscience might make it possible to develop techniques for directly altering offenders’ brains, in order to make offenders more responsible and law-abiding. The idea of using such techniques within the criminal justice system can seem intuitively troubling, even if they were more effective in preventing crime than traditional methods of rehabilitation. One standard argument against this use of brain interventions is that it would undermine the individual’s free will. This paper maintains that ‘free will’ (at least, (...)
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  6. J. M. Fleming & T. Ownsworth (2006). A Review of Awareness Interventions in Brain Injury Rehabilitation. [REVIEW] Neuropsychological Rehabilitation 16 (4):474-500.score: 42.0
  7. S. Holm (2004). Irreversible Bodily Interventions in Children. Journal of Medical Ethics 30 (3):237-237.score: 42.0
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  8. Antoine Baumann, Frederique Claudot, Gerard Audibert, Paul-Michel Mertes & Louis Puybasset (2011). The Ethical and Legal Aspects of Palliative Sedation in Severely Brain Injured Patients: A French Perspective. Philosophy, Ethics, and Humanities in Medicine 6 (1):4-.score: 38.0
    To fulfill their crucial duty of relieving suffering in their patients, physicians may have to administer palliative sedation when they implement treatment-limitation decisions such as the withdrawal of life-supporting interventions in patients with poor prognosis chronic severe brain injury. The issue of palliative sedation deserves particular attention in adults with serious brain injuries and in neonates with severe and irreversible brain lesions, who are unable to express pain or to state their wishes. In France, treatment (...)
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  9. H. Madder (2012). Treatment Interventions for Severe Traumatic Brain Injury: Limited Evidence, Choice Limitations. Journal of Medical Ethics 38 (11):662-663.score: 36.0
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  10. Joseph L. Verheijde, Mohamed Y. Rady & Joan L. McGregor (2009). Brain Death, States of Impaired Consciousness, and Physician-Assisted Death for End-of-Life Organ Donation and Transplantation. Medicine, Health Care and Philosophy 12 (4):409-421.score: 29.0
    In 1968, the Harvard criteria equated irreversible coma and apnea (i.e., brain death) with human death and later, the Uniform Determination of Death Act was enacted permitting organ procurement from heart-beating donors. Since then, clinical studies have defined a spectrum of states of impaired consciousness in human beings: coma, akinetic mutism (locked-in syndrome), minimally conscious state, vegetative state and brain death. In this article, we argue against the validity of the Harvard criteria for equating brain death (...)
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  11. Sergio Bagnato, Cristina Boccagni, Antonino Sant'Angelo, Alexander A. Fingelkurts, Andrew A. Fingelkurts & Giuseppe Galardi (2013). Emerging From an Unresponsive Wakefulness Syndrome: Brain Plasticity has to Cross a Threshold Level. Neuroscience and Biobehavioral Reviews 37 (10):2721-2736.score: 27.0
    Unresponsive wakefulness syndrome (UWS, previously known as vegetative state) occurs after patients survive a severe brain injury. Patients suffering from UWS have lost awareness of themselves and of the external environment and do not retain any trace of their subjective experience. Current data demonstrate that neuronal functions subtending consciousness are not completely reset in UWS; however, they are reduced below the threshold required to experience consciousness. The critical factor that determines whether patients will recover consciousness is the distance of (...)
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  12. Dominik Groß (2009). Blessing or Curse? Neurocognitive Enhancement by “Brain Engineering”. Medicine Studies 1 (4):379-391.score: 27.0
    PurposeSince the 1980s we have witnessed a soaring “extra-therapeutic” use of psycho-pharmacology. But there is also an increasing interest in invasive methods of neuroenhancement that can be subsumed under the term “brain engineering”. The present article aims to identify key issues raised by those forms of neuro-technical enhancement (e.g., deep brain stimulation, brain-computer interfaces, memory chips, neurobionic interventions). First it distinguishes different forms of neuroenhancement, then describes features of those methods and finally discusses their ethical implications.MethodsThe (...)
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  13. D. Rodríguez-Arias, J. C. Tortosa, C. J. Burant, P. Aubert, M. P. Aulisio & S. J. Youngner (2013). One or Two Types of Death? Attitudes of Health Professionals Towards Brain Death and Donation After Circulatory Death in Three Countries. Medicine, Health Care and Philosophy 16 (3):457-467.score: 27.0
    This study examined health professionals’ (HPs) experience, beliefs and attitudes towards brain death (BD) and two types of donation after circulatory death (DCD)—controlled and uncontrolled DCD. Five hundred and eighty-seven HPs likely to be involved in the process of organ procurement were interviewed in 14 hospitals with transplant programs in France, Spain and the US. Three potential donation scenarios—BD, uncontrolled DCD and controlled DCD—were presented to study subjects during individual face-to-face interviews. Our study has two main findings: (1) In (...)
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  14. Brian Levine, Tom A. Schweizer, Charlene O'Connor, Gary Turner, Susan Gillingham, Donald T. Stuss, Tom Manly & Ian H. Robertson (2011). Rehabilitation of Executive Functioning in Patients with Frontal Lobe Brain Damage with Goal Management Training. Frontiers in Human Neuroscience 5.score: 27.0
    Executive functioning deficits due to brain disease affecting frontal lobe functions cause significant real-life disability, yet solid evidence in support of executive functioning interventions is lacking. Goal Management Training (GMT), an executive functioning intervention that draws upon theories concerning goal processing and sustained attention, has received empirical support in studies of patients with traumatic brain injury, normal aging, and case studies. GMT promotes a mindful approach to complex real-life tasks that pose problems for patients with executive functioning (...)
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  15. S. K. Pandya (2011). Understanding Brain, Mind and Soul: Contributions From Neurology and Neurosurgery. Mens Sana Monographs 9 (1):129.score: 27.0
    Treatment of diseases of the brain by drugs or surgery necessitates an understanding of its structure and functions. The philosophical neurosurgeon soon encounters difficulties when localising the abstract concepts of mind and soul within the tangible 1300-gram organ containing 100 billion neurones. Hippocrates had focused attention on the brain as the seat of the mind. The tabula rasa postulated by Aristotle cannot be localised to a particular part of the brain with the confidence that we can localise (...)
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  16. Frederic Gilbert, Andrej Vranic & Samia Hurst (2013). Involuntary & Voluntary Invasive Brain Surgery: Ethical Issues Related to Acquired Aggressiveness. [REVIEW] Neuroethics 6 (1):115-128.score: 23.0
    Clinical cases of frontal lobe lesions have been significantly associated with acquired aggressive behaviour. Restoring neuronal and cognitive faculties of aggressive individuals through invasive brain intervention raises ethical questions in general. However, more questions have to be addressed in cases where individuals refuse surgical treatment. The ethical desirability and permissibility of using intrusive surgical brain interventions for involuntary or voluntary treatment of acquired aggressiveness is highly questionable. This article engages with the description of acquired aggressiveness in general, (...)
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  17. Mark M. Kishiyama Rajeev D. S. Raizada (2010). Effects of Socioeconomic Status on Brain Development, and How Cognitive Neuroscience May Contribute to Levelling the Playing Field. Frontiers in Human Neuroscience 4.score: 23.0
    The study of socioeconomic status (SES) and the brain finds itself in a circumstance unusual for Cognitive Neuroscience: large numbers of questions with both practical and scientific importance exist, but they are currently under-researched and ripe for investigation. This review aims to highlight these questions, to outline their potential significance, and to suggest routes by which they might be approached. Although remarkably few neural studies have been carried out so far, there exists a large literature of previous behavioural work. (...)
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  18. William P. Bechtel (2002). Decomposing the Brain: A Long Term Pursuit. [REVIEW] Brain and Mind 3 (1):229-242.score: 21.0
    This paper defends cognitive neuroscience’s project of developing mechanistic explan- ations of cognitive processes through decomposition and localization against objections raised by William Uttal in The New Phrenology. The key issue between Uttal and researchers pursuing cognitive neuroscience is that Uttal bets against the possibility of decomposing mental operations into component elementary operations which are localized in distinct brain regions. The paper argues that it is through advancing and revising what are likely to be overly simplistic and incorrect decompositions (...)
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  19. Max Velmans (2002). How Could Conscious Experiences Affect Brains? Journal of Consciousness Studies 9 (11):3-29.score: 21.0
    In everyday life we take it for granted that we have conscious control of some of our actions and that the part of us that exercises control is the conscious mind. Psychosomatic medicine also assumes that the conscious mind can affect body states, and this is supported by evidence that the use of imagery, hypnosis, biofeedback and other ‘mental interventions’ can be therapeutic in a variety of medical conditions. However, there is no accepted theory of mind/body interaction and this (...)
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  20. Robert M. Veatch (2005). The Death of Whole-Brain Death: The Plague of the Disaggregators, Somaticists, and Mentalists. Journal of Medicine and Philosophy 30 (4):353 – 378.score: 21.0
    In its October 2001 issue, this journal published a series of articles questioning the Whole-Brain-based definition of death. Much of the concern focused on whether somatic integration - a commonly understood basis for the whole-brain death view - can survive the brain's death. The present article accepts that there are insurmountable problems with whole-brain death views, but challenges the assumption that loss of somatic integration is the proper basis for pronouncing death. It examines three major themes. (...)
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  21. Georg Northoff (2001). "Brain-Paradox" and "Embeddment": Do We Need a "Philosophy of the Brain"? Brain and Mind 195 (2):195-211.score: 21.0
    Present discussions in philosophy of mind focuson ontological and epistemic characteristics ofmind and on mind-brain relations. In contrast,ontological and epistemic characteristics ofthe brain have rarely been thematized. Rather,philosophy seems to rely upon an implicitdefinition of the brain as "neuronal object''and "object of recognition'': henceontologically and epistemically distinct fromthe mind, characterized as "mental subject'' and"subject of recognition''. This leads to the"brain-paradox''. This ontological and epistemicdissociation between brain and mind can beconsidered central for the problems of mind (...)
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  22. Andrew A. Fingelkurts & Alexander A. Fingelkurts (2001). Operational Architectonics of the Human Brain Biopotential Field: Toward Solving the Mind-Brain Problem. [REVIEW] Brain and Mind 2 (3):261-296.score: 21.0
    The understanding of the interrelationship between brain and mind remains far from clear. It is well established that the brain's capacity to integrate information from numerous sources forms the basis for cognitive abilities. However, the core unresolved question is how information about the "objective" physical entities of the external world can be integrated, and how unifiedand coherent mental states (or Gestalts) can be established in the internal entities of distributed neuronal systems. The present paper offers a unified methodological (...)
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  23. Ullin T. Place (2000). The Two Factor Theory of the Mind-Brain Relation. Brain and Mind 1 (1):29-43.score: 21.0
    The analysis of mental concepts suggests that the distinctionbetween the mental and the nonmental is not ontologically fundamental,and that, whereas mental processes are one and the same things as thebrain processes with which they are correlated, dispositional mentalstates depend causally on and are, thus, ''''distinct existences'''' fromthe states of the brain microstructure with which ''they'' are correlated.It is argued that this difference in the relation between an entity andits composition/underlying structure applies across the board. allstuffs and processes are the (...)
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  24. Edmund T. Rolls (2000). Précis of the Brain and Emotion. Behavioral and Brain Sciences 23 (2):177-191.score: 21.0
    The topics treated in The brain and emotion include the definition, nature, and functions of emotion (Ch. 3); the neural bases of emotion (Ch. 4); reward, punishment, and emotion in brain design (Ch. 10); a theory of consciousness and its application to understanding emotion and pleasure (Ch. 9); and neural networks and emotion-related learning (Appendix). The approach is that emotions can be considered as states elicited by reinforcers (rewards and punishers). This approach helps with understanding the functions of (...)
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  25. Adrian Carter, Emily Bell, Eric Racine & Wayne Hall (2011). Ethical Issues Raised by Proposals to Treat Addiction Using Deep Brain Stimulation. Neuroethics 4 (2):129-142.score: 21.0
    Deep brain stimulation (DBS) has been proposed as a potential treatment of drug addiction on the basis of its effects on drug self-administration in animals and on addictive behaviours in some humans treated with DBS for other psychiatric or neurological conditions. DBS is seen as a more reversible intervention than ablative neurosurgery but it is nonetheless a treatment that carries significant risks. A review of preclinical and clinical evidence for the use of DBS to treat addiction suggests that more (...)
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  26. Michael L. Anderson (2010). Neural Reuse: A Fundamental Organizational Principle of the Brain. Behavioral and Brain Sciences 33 (4):245.score: 21.0
    An emerging class of theories concerning the functional structure of the brain takes the reuse of neural circuitry for various cognitive purposes to be a central organizational principle. According to these theories, it is quite common for neural circuits established for one purpose to be exapted (exploited, recycled, redeployed) during evolution or normal development, and be put to different uses, often without losing their original functions. Neural reuse theories thus differ from the usual understanding of the role of neural (...)
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  27. Mariale Hardiman, Luke Rinne, Emma Gregory & Julia Yarmolinskaya (2012). Neuroethics, Neuroeducation, and Classroom Teaching: Where the Brain Sciences Meet Pedagogy. [REVIEW] Neuroethics 5 (2):135-143.score: 21.0
    The popularization of neuroscientific ideas about learning—sometimes legitimate, sometimes merely commercial—poses a real challenge for classroom teachers who want to understand how children learn. Until teacher preparation programs are reconceived to incorporate relevant research from the neuro- and cognitive sciences, teachers need translation and guidance to effectively use information about the brain and cognition. Absent such guidance, teachers, schools, and school districts may waste time and money pursuing so called brain-based interventions that lack a firm basis in (...)
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  28. Giorgio Vallortigara & Lesley J. Rogers (2005). Survival with an Asymmetrical Brain: Advantages and Disadvantages of Cerebral Lateralization. Behavioral and Brain Sciences 28 (4):575-589.score: 21.0
    Recent evidence in natural and semi-natural settings has revealed a variety of left-right perceptual asymmetries among vertebrates. These include preferential use of the left or right visual hemifield during activities such as searching for food, agonistic responses, or escape from predators in animals as different as fish, amphibians, reptiles, birds, and mammals. There are obvious disadvantages in showing such directional asymmetries because relevant stimuli may be located to the animal's left or right at random; there is no a priori association (...)
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  29. David Loye (2002). The Moral Brain. Brain and Mind 3 (1):133-150.score: 21.0
    This article probes the evolutionary origins ofmoral capacities and moral agency. From thisit develops a theory of the guidancesystem of higher mind (GSHM). The GSHM is ageneral model of intelligence whereby moralfunctioning is integrated with cognitive,affective, and conative functioning, resultingin a flow of information between eight brainlevels functioning as an evaluative unitbetween stimulus and response.The foundation of this view of morality and ofcaring behavior is Charles Darwin's theory,largely ignored until recently, of thegrounding of morality in sexual instincts whichlater expand into (...)
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  30. Tom Tomlinson (1984). The Conservative Use of the Brain-Death Criterion – a Critique. Journal of Medicine and Philosophy 9 (4):377-394.score: 21.0
    The whole brain-death criterion of death now enjoys a wide acceptance both within the medical profession and among the general public. That acceptance is in large part the product of the contention that brain death is the proper criterion for even a conservative definition of death – the irreversible loss of the integrated functioning of the organism as a whole. This claim – most recently made in the report of the Presidential Commission and in a comprehensive article (...)
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  31. Péter Érdi (2000). On the 'Dynamic Brain' Metaphor. Brain and Mind 1 (1):119-145.score: 21.0
    Dynamic systems theory offers conceptual andmathematical tools for describing the performance ofneural systems at very different levels oforganization. Three aspects of the dynamic paradigmare discussed, namely neural rhythms, neural andmental development, and macroscopic brain theories andmodels.
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  32. Jonathan Kenneth Burns (2004). An Evolutionary Theory of Schizophrenia: Cortical Connectivity, Metarepresentation, and the Social Brain. Behavioral and Brain Sciences 27 (6):831-855.score: 21.0
    Schizophrenia is a worldwide, prevalent disorder with a multifactorial but highly genetic aetiology. A constant prevalence rate in the face of reduced fecundity has caused some to argue that an evolutionary advantage exists in unaffected relatives. Here, I critique this adaptationist approach, and review – and find wanting – Crow's “speciation” hypothesis. In keeping with available biological and psychological evidence, I propose an alternative theory of the origins of this disorder. Schizophrenia is a disorder of the social brain, and (...)
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  33. Veronica Johansson, Martin Garwicz, Martin Kanje, Helena Röcklinsberg, Jens Schouenborg, Anders Tingström & Ulf Görman (2013). Beyond Blind Optimism and Unfounded Fears: Deep Brain Stimulation for Treatment Resistant Depression. Neuroethics 6 (3):457-471.score: 21.0
    The introduction of new medical treatments based on invasive technologies has often been surrounded by both hopes and fears. Hope, since a new intervention can create new opportunities either in terms of providing a cure for the disease or impairment at hand; or as alleviation of symptoms. Fear, since an invasive treatment involving implanting a medical device can result in unknown complications such as hardware failure and undesirable medical consequences. However, hopes and fears may also arise due to the cultural (...)
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  34. Robert P. O'Shea & Paul M. Corballis (2001). Binocular Rivalry Between Complex Stimuli in Split-Brain Observers. Brain and Mind 2 (1):151-160.score: 21.0
    We investigated binocular rivalry in the twocerebral hemispheres of callosotomized(split-brain) observers. We found that rivalryoccurs for complex stimuli in split-brainobservers, and that it is similar in the twohemispheres. This poses difficulties for twotheories of rivalry: (1) that rivalry occursbecause of switching of activity between thetwo hemispheres, and (2) that rivalry iscontrolled by a structure in the rightfrontoparietal cortex. Instead, similar rivalryfrom the two hemispheres is consistent with atheory that its mechanism is low in the visualsystem, at which each hemisphere (...)
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  35. L. R. Talbot & H. A. Whitaker (1994). Brain-Injured Persons in an Altered State of Consciousness: Measures and Intervention Strategies. Brain Injury 8:689-99.score: 21.0
  36. G. Northoff (2001). Brain-Paradox” and “Embeddment” – Do We Need a “Philosophy of the Brain”? Brain and Mind 2 (2):195-211.score: 21.0
    Present discussions in philosophy of mind focuson ontological and epistemic characteristics ofmind and on mind-brain relations. In contrast,ontological and epistemic characteristics ofthe brain have rarely been thematized. Rather,philosophy seems to rely upon an implicitdefinition of the brain as "neuronal object''and "object of recognition'': henceontologically and epistemically distinct fromthe mind, characterized as "mental subject'' and"subject of recognition''. This leads to the"brain-paradox''. This ontological and epistemicdissociation between brain and mind can beconsidered central for the problems of mind (...)
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  37. A. Browne (1983). Whole-Brain Death Reconsidered. Journal of Medical Ethics 9 (1):28-44.score: 21.0
    The author, a philosopher, suggests that the concept of death should be left as it is 'in its present indeterminate state', and that we ought to reject attempts to define death in terms of whole-brain death or any other type of brain death, including cerebral death and 'irreversible coma'. Instead of 'fiddling with the definition of death' clear rules should be established specifying 'what can be appropriately done to whom when'.
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  38. Barbara L. Finlay, Richard B. Darlington & Nicholas Nicastro (2001). Developmental Structure in Brain Evolution. Behavioral and Brain Sciences 24 (2):263-278.score: 21.0
    How does evolution grow bigger brains? It has been widely assumed that growth of individual structures and functional systems in response to niche-specific cognitive challenges is the most plausible mechanism for brain expansion in mammals. Comparison of multiple regressions on allometric data for 131 mammalian species, however, suggests that for 9 of 11 brain structures taxonomic and body size factors are less important than covariance of these major structures with each other. Which structure grows biggest is largely predicted (...)
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  39. R. D. Strous, T. Bergman-Levy & B. Greenberg (2012). Postmortem Brain Donation and Organ Transplantation in Schizophrenia: What About Patient Consent? Journal of Medical Ethics 38 (7):442-444.score: 21.0
    In patients with schizophrenia, consent postmortem for organ donation for transplantation and research is usually obtained from relatives. By means of a questionnaire, the authors investigate whether patients with schizophrenia would agree to family members making such decisions for them as well as compare decisions regarding postmortem organ transplantation and brain donation between patients and significant family members. Study results indicate while most patients would not agree to transplantation or brain donation for research, a proportion would agree. Among (...)
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  40. Walter Glannon (2014). Intervening in the Psychopath's Brain. Theoretical Medicine and Bioethics 35 (1):43-57.score: 21.0
    Psychopathy is a disorder involving personality and behavioral features associated with a high rate of violent aggression and recidivism. This paper explores potential psychopharmacological therapies to modulate dysfunctional neural pathways in psychopaths and reduce the incidence of their harmful behavior, as well as the ethical and legal implications of offering these therapies as an alternative to incarceration. It also considers whether forced psychopharmacological intervention in adults and children with psychopathic traits manifesting in violent behavior can be justified. More generally, the (...)
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  41. V. S. Ramachandran, Brain.score: 21.0
    This article reviews the potential use of visual feedback, focusing on mirror visual feedback, introduced over 15 years ago, for the treatment of many chronic neurological disorders that have long been regarded as intractable such as phantom pain, hemiparesis from stroke and complex regional pain syndrome. Apart from its clinical importance, mirror visual feedback paves the way for a paradigm shift in the way we approach neurological disorders. Instead of resulting entirely from irreversible damage to specialized brain modules, (...)
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  42. Frederic Gilbert (2012). The Burden of Normality: From 'Chronically Ill' to 'Symptom Free'. New Ethical Challenges for Deep Brain Stimulation Postoperative Treatment. Journal of Medical Ethics 8 (7):408-412.score: 21.0
    Although an invasive medical intervention, Deep Brain Stimulation (DBS) has been regarded as an efficient and safe treatment of Parkinson’s disease for the last 20 years. In terms of clinical ethics, it is worth asking whether the use of DBS may have unanticipated negative effects similar to those associated with other types of psychosurgery. Clinical studies of epileptic patients who have undergone an anterior temporal lobectomy have identified a range of side effects and complications in a number of domains: (...)
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  43. Walter M. High, Angelle M. Sander, Margaret A. Struchen & Karen A. Hart (eds.) (2005). Rehabilitation for Traumatic Brain Injury. Oxford University Press.score: 21.0
    Rehabilitation For Traumatic Brain Injury (TBI) is a state-of-the-science review of the effectiveness of rehabilitation interventions.
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  44. Ronald A. Carson, Jaime L. Frias & Richard J. Melker (1981). Case Study: Research with Brain-Dead Children. [REVIEW] Bioethics Quarterly 3 (1):50-53.score: 21.0
    The esophageal obturator airway (EOA) is a device used throughout the United States to facilitate artificial respiration of critically ill patients who are not hospitalized. Its use is restricted to persons who are over 15 years old because obturators for children are not available. A protocol submitted to an institutional review board (IRB) intended to develop EOAs suitable for use in children. The investigators proposed to perform preliminary testing of these devices on children who had sustained irreversible loss of (...)
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  45. Lucas C. Parra Davide Reato, Asif Rahman, Marom Bikson (2013). Effects of Weak Transcranial Alternating Current Stimulation on Brain Activity—a Review of Known Mechanisms From Animal Studies. Frontiers in Human Neuroscience 7.score: 21.0
    Rhythmic neuronal activity is ubiquitous in the human brain. These rhythms originate from a variety of different network mechanisms, which give rise to a wide-ranging spectrum of oscillation frequencies. In the last few years an increasing number of clinical research studies have explored transcranial alternating current stimulation (tACS) with weak current as a tool for affecting brain function. The premise of these interventions is that tACS will interact with ongoing brain oscillations. However, the exact mechanisms by (...)
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  46. Maria G. Knyazeva Elham Barzegaran, Amir Joudaki, Mahdi Jalili, Andrea O. Rossetti, Richard S. Frackowiak (2012). Properties of Functional Brain Networks Correlate with Frequency of Psychogenic Non-Epileptic Seizures. Frontiers in Human Neuroscience 6.score: 21.0
    Abnormalities in the topology of brain networks may be an important feature and etiological factor for psychogenic non-epileptic seizures (PNES). To explore this possibility, we applied a graph theoretical approach to functional networks based on resting state EEGs from 13 PNES patients and 13 age- and gender-matched controls. The networks were extracted from Laplacian-transformed time-series by a cross-correlation method. PNES patients showed close to normal local and global connectivity and small-world structure, estimated with clustering coefficient, modularity, global efficiency, and (...)
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  47. S. Honeybul, K. M. Ho & G. R. Gillett (2014). Traumatic Brain Injury: An Objective Model of Consent. [REVIEW] Neuroethics 7 (1):11-18.score: 21.0
    The aim of this paper was to explore the issue of consent when considering the use of a life saving but not necessarily restorative surgical intervention for severe traumatic brain injury. A previous study has investigated the issue amongst 500 healthcare workers by using a two-part structured interview to assess opinion regarding decompressive craniectomy for three patients with varying injury severity. A visual analogue scale was used to assess the strengths of their opinions both before and after being shown (...)
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  48. Roland Puccetti (1981). The Case for Mental Duality: Evidence From Split-Brain Data and Other Considerations. Behavioral and Brain Sciences 4 (1):93-123.score: 21.0
    Contrary to received opinion among philosophers, psychologists, and neuroscientists, conscious duality as a principle of brain organization is neither incoherent nor demonstrably false. The present paper begins by reviewing the history of the theory and its anatomical basis and defending it against the claim that it rests upon an arbitrary decision as to what constitutes the biological substratum of mind or person.
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  49. Dirk Wildgruber Benjamin Kreifelts, Heike Jacob, Carolin Brück, Michael Erb, Thomas Ethofer (2013). Non-Verbal Emotion Communication Training Induces Specific Changes in Brain Function and Structure. Frontiers in Human Neuroscience 7.score: 21.0
    The perception of emotional cues from voice and face is essential for social interaction. However, this process is altered in various psychiatric conditions along with impaired social functioning. Emotion communication trainings have been demonstrated to improve social interaction in healthy individuals and to reduce emotional communication deficits in psychiatric patients. Here, we investigated the impact of a nonverbal emotion communication training (NECT) on cerebral activation and brain structure in a controlled and combined functional magnetic resonance imaging and voxel-based morphometry (...)
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  50. Barbara Fajardo (2000). Breaks in Consciousness in the Psychoanalytic Process: A Dynamic Systems Approach to Change and a Bridge to Edelman's Mind/Brain Model. Annual of Psychoanalysis 28:21-45.score: 21.0
     
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