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  1. James A. Marcum (2014). Hillel D. Braude: Intuition in Medicine: A Philosophical Defense of Clinical Reasoning. Theoretical Medicine and Bioethics 35 (5):401-405.
    The book starts with a scandal, that is, Socrates’s mortality as entailed in the Aristotelian syllogism,All men are mortal,Socrates is a man,Therefore, Socrates is mortal. The scandal pertains to the deduction of Socrates’s death from the logical connections of premises, which, according to Braude, renders it “meaningless.” But, what does this scandal have to do with a philosophical defense of intuition in medicine? For Braude, the scandal is emblematic of a crisis in medicine and philosophy—a crisis in which human mortality (...)
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  2. James A. Marcum (2012). An Integrated Model of Clinical Reasoning: Dual‐Process Theory of Cognition and Metacognition. Journal of Evaluation in Clinical Practice 18 (5):954-961.
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  3. James A. Marcum (2012). 3 From Paradigm to Disciplinary Matrix and Exemplar. In Vasō Kintē & Theodore Arabatzis (eds.), Kuhn's the Structure of Scientific Revolutions Revisited. Routledge. 41.
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  4. James A. Marcum (2012). Johnson, Lawrence E: A Life-Centered Approach to Bioethics: Biocentric Ethics. [REVIEW] Theoretical Medicine and Bioethics 33 (3):227-231.
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  5. James A. Marcum (2011). Care and Competence in Medical Practice: Francis Peabody Confronts Jason Posner. [REVIEW] Medicine, Health Care and Philosophy 14 (2):143-153.
    In this paper, I discuss the role of care and competence, as well as their relationship to one another, in contemporary medical practice. I distinguish between two types of care. The first type, care1, represents a natural concern that motivates physicians to help or to act on the behalf of patients, i.e. to care about them. However, this care cannot guarantee the correct technical or right ethical action of physicians to meet the bodily and existential needs of patients, i.e. to (...)
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  6. James A. Marcum (2011). Horizon for Scientific Practice: Scientific Discovery and Progress. International Studies in the Philosophy of Science 24 (2):187-215.
    In this article, I introduce the notion of horizon for scientific practice (HSP), representing limits or boundaries within which scientists ply their trade, to facilitate analysis of scientific discovery and progress. The notion includes not only constraints that delimit scientific practice, e.g. of bringing experimentation to a temporary conclusion, but also possibilities that open up scientific practice to additional scientific discovery and to further scientific progress. Importantly, it represents scientific practice as a dynamic and developmental integration of activities to investigate (...)
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  7. James A. Marcum (2011). Jeremy Howick: The Philosophy of Evidence-Based Medicine. [REVIEW] Medicine Studies 3 (2):125-128.
  8. James A. Marcum (2011). Medical Cure and Progress The Case of Type-1 Diabetes. Perspectives in Biology and Medicine 54 (2):176-188.
    What is medical progress? The answer to this question is often associated with advances in diagnostic technology, with greater understanding of disease or pathological mechanisms particularly at the molecular level, or with the discovery of drugs and the developmental of surgical procedures to treat diseases. However, this facile answer can be problematic. In a New York Times Magazine article, for example, Lisa Sanders (2003) recounts a lecture delivered to her first-year class, at a "white-coat" ceremony, by the medical school dean. (...)
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  9. James A. Marcum (2011). The Role of Prudent Love in the Practice of Clinical Medicine. Journal of Evaluation in Clinical Practice 17 (5):877-882.
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  10. James A. Marcum (2010). Ingvar Johansson, Neils Lynøe: Medicine & Philosophy: A Twenty-First Century Introduction. Theoretical Medicine and Bioethics 31 (5):395-399.
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  11. James A. Marcum (2009). Human Origins and Human Nature. Faith and Philosophy 26 (5):566-570.
    Both religion and science provide powerful images of human origins and human nature. Often these images are seen as incompatible or irreconcilable, with the religious image generally marginalized vis-à-vis the scientific image. Recent genetic studies into human origins, especially in terms of common cellular features like the mitochondrion from females and the Y-chromosome from males, provide evidence for common ancestors called mitochondrial Eve and Y-chromosomal Adam. The aim of this paper is to expound upon the Judeo-Christian and western scientific images (...)
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  12. James A. Marcum (2009). The Epistemically Virtuous Clinician. Theoretical Medicine and Bioethics 30 (3):249-265.
    Today, modern Western medicine is facing a quality-of-care crisis that is undermining the patient–physician relationship. In this paper, a notion of the epistemically virtuous clinician is proposed in terms of both the reliabilist and responsibilist versions of virtue epistemology, in order to help address this crisis. To that end, a clinical case study from the literature is first reconstructed. The reliabilist intellectual virtues, including the perceptual and conceptual virtues, are then discussed and applied to the case study. Next, a similar (...)
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  13. James A. Marcum (2009). The Nature of Light and Color: Goethe's “der Versuch AlS Vermittler” Versus Newton's Experimentum Crucis. Perspectives on Science 17 (4):pp. 457-481.
  14. Bryce Huebner, Janette Dinishak, James A. Marcum & Jelle De Schrijver (2008). Reviews. [REVIEW] Philosophical Psychology 21 (6):843 – 858.
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  15. James A. Marcum (2008). Reflections on Humanizing Biomedicine. Perspectives in Biology and Medicine 51 (3):392-405.
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  16. James A. Marcum (2008). Instituting Science: Discovery or Construction of Scientific Knowledge? International Studies in the Philosophy of Science 22 (2):185 – 210.
    Is knowledge in the natural sciences discovered or constructed? For objectivists, scientific knowledge is discovered through investigations into a mind-independent, natural world. For constructivists, such knowledge is produced through negotiations among members of a professional guild. I examine the clash between the two positions and propose that scientific knowledge is the concurrent outcome from investigations into a natural world and from consensus reached through negotiations of a professional guild. Specifically, I introduce the general methodological notion, instituting science, which incorporates both (...)
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  17. James A. Marcum (2008). Whitehead's Philosophy of Organism and Systems Biology. Chromatikon: Annales de la Philosophie En Procès / Yearbook of Philosophy in Process 4:143-152.
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  18. James A. Marcum (2007). Experimental Series and the Justification of Temin's DNA Provirus Hypothesis. Synthese 154 (2):259 - 292.
    A notion of experimental series is developed, in which experiments or experimental sets are connected through experimental suggestions arising from previous experimental outcomes. To that end, the justification of Howard Temin’s DNA provirus hypothesis is examined. The hypothesis originated with evidence from two exploratory experimental sets on an oncogenic virus and was substantiated by including evidence from three additional experimental sets. Collectively these sets comprise an experimental series and the accumulative evidence from the series was adequate to justify the hypothesis (...)
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  19. James A. Marcum (2007). Montgomery, Kathryn, How Doctors Think: Clinical Judgment and the Practice of Medicine. Theoretical Medicine and Bioethics 28 (6):525-530.
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  20. James A. Marcum (2006). Book Review. [REVIEW] Theoretical Medicine and Bioethics 27 (3).
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  21. James A. Marcum (2006). 'Soup' Vs. 'Sparks': Alexander Forbes and the Synaptic Transmission Controversy. Annals of Science 63 (2):139-156.
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  22. James A. Marcum (2005). Biomechanical and Phenomenological Models of the Body, the Meaning of Illness and Quality of Care. Medicine, Health Care and Philosophy 7 (3):311-320.
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  23. James A. Marcum (2005). Metaphysical Presuppositions and Scientific Practices: Reductionism and Organicism in Cancer Research. International Studies in the Philosophy of Science 19 (1):31 – 45.
    Metaphysical presuppositions are important for guiding scientific practices and research. The success of twentieth-century biology, for instance, is largely attributable to presupposing that complex biological processes are reducible to elementary components. However, some biologists have challenged the sufficiency of reductionism for investigating complex biological phenomena and have proposed alternative presuppositions like organicism. In this article, contemporary cancer research is used as a case study to explore the importance of metaphysical presuppositions for guiding research. The predominant paradigm directing cancer research is (...)
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  24. James A. Marcum & Carolyn M. Soke (2005). The End of Modern Medicine: Biomedical Science Under a Microscope. Journal of Medical Humanities 26 (2):191-193.
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  25. James A. Marcum (2001). Constructing a Scientific Paper: Howell's Prothrombin Laboratory Notebook and Paper. International Studies in the Philosophy of Science 15 (3):293 – 310.
    Scientists generally record their laboratory activities and experimental results in notebooks, from which they construct scientific papers. The Johns Hopkins physiologist William Henry Howell kept a laboratory notebook from 1913 to 1914, in which he recorded experiments on the blood clotting factor prothrombin. In 1914 he published a paper using this notebook, to justify his theory of prothrombin activation. Howell's paper is reconstructed, in terms of its narrative and argument elements, from the laboratory activities and experimental results recorded in the (...)
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  26. James A. Marcum (1998). Defending the Priority of 'Remarkable Researches': The Discovery of Fibrin Ferment. History and Philosophy of the Life Sciences 20 (1):51 - 76.
    At times scientists manipulate their community's perception of scientific discoveries. The following case study illustrates the extent to which a community's understanding of a discovery was influenced by one of its members. In the 1870s the British physiologist Arthur Gamgee undertook a campaign to insure Andrew Buchanan of Glasgow credit for his blood clotting research, conducted from the early 1830s to the mid-1840s. Gamgee endeavored to establish Buchanan as the discoverer of fibrin ferment, a clotting factor first isolated and named (...)
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  27. James A. Marcum (1995). The Discovery of Heparin Revisited: The Peptone Connection. Perspectives in Biology and Medicine 39 (4):610-625.
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  28. James A. Marcum & Geert M. N. Verschuuren (1986). Hemostatic Regulation and Whitehead's Philosophy of Organism. Acta Biotheoretica 35 (1-2).
    Biology as a scientific discipline has relied heavily upon advances in chemistry and physics. An inherent danger in this relationship is the reduction of living phenomena to physico-chemical terms. Whitehead's Philosophy of Organism is utilized to examine current methodologies within biology and to evaluate their appropriateness for future research. Hemostatic regulation is employed to illustrate the applications of organistic concepts to biological research. It is concluded that understanding of living entities and their properties as well as possibly life itself will (...)
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