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  1. Matthias Schmidt, Jennifer Marshall, Jocelyn Downie & Michael Hadskis (2011). Pediatric Magnetic Resonance Research and the Minimal-Risk Standard. Irb: Ethics and Human Research 33 (5):1-6.
    While an accurate assessment of risk is always important, it is especially so in pediatric research. Recognizing the pivotal nature of the minimal-risk standard, we set out to determine under what circumstances pediatric magnetic resonance imaging research does or does not meet this standard. We found that while the physical and psychological risks that attend the MRI procedure do not exceed minimal risk, the sedation and contrast enhancement that are sometimes associated with MRI research do, as both exceed the level (...)
     
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  2. Jennifer Marshall & Michael Hadskis (2009). Canadian Research Ethics Boards, MRI Research Risks, and MRI Risk Classification. Irb: Ethics and Human Research 31 (4):9-15.
    In order to illuminate the potential harms of MRI research, we present data obtained by examining MRI research proposal files that had been submitted for review to several Canadian Research Ethics Boards. The data reveal that REB review of the studies contained omissions, considerable variability, and sometimes confusion regarding MRI research risks and risk classification. If our findings reflect the general state of REB review of MRI research in Canada and elsewhere, there is a pressing need for REBs to be (...)
     
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  3. Jocelyn Downie & Jennifer Marshall (2007). Pediatric Neuroimaging Ethics. Cambridge Quarterly of Healthcare Ethics 16 (02):147-160.
    Neuroimaging has provided insight into numerous neurological disorders in children, such as epilepsy and cerebral palsy. Many clinicians and investigators believe that neuroimaging holds great promise, especially in the areas of behavioral and cognitive disorders. However, concerns about the risks of various neuroimaging modalities and the potential for misinterpretation of imaging results are mounting. Imaging evaluations also raise questions about stigmatization, allocation of resources, and confidentiality. Children are particularly vulnerable in this milieu and require special attention with regards to safety (...)
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  4. Jocelyn Downie, Matthais Schmidt, Nuala Kenny, Ryan D’Arcy, Michael Hadskis & Jennifer Marshall (2007). Paediatric MRI Research Ethics: The Priority Issues. [REVIEW] Journal of Bioethical Inquiry 4 (2):85-91.
    In this paper, we first briefly describe neuroimaging technology, our reasons for studying magnetic resonance imaging (MRI) technology, and then provide a discussion of what we have identified as priority issues for paediatric MRI research. We examine the issues of respectful involvement of children in the consent process as well as privacy and confidentiality for this group of MRI research participants. In addition, we explore the implications of unexpected findings for paediatric MRI research participants. Finally, we explore the ethical issues (...)
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  5. Jennifer Marshall (2006). Life Extension Research: An Analysis of Contemporary Biological Theories and Ethical Issues. [REVIEW] Medicine, Health Care and Philosophy 9 (1):87-96.
    Many opinions and ideas about aging exist. Biological theories have taken hold of the popular and scientific imagination as potential answers to a “cure” for aging. However, it is not clear what exactly is being cured or whether aging could be classified as a disease. Some scientists are convinced that aging will be biologically alterable and that the human lifespan will be vastly extendable. Other investigators believe that aging is an elusive target that may only be “statistically” manipulatable through a (...)
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  6. Jennifer Marshall, The Development of Contemporary Medical Genetics Research Models and the Need for Scientific Responsibility.
    Current medical genetics research is dominated by a single theory that supports the Human Genome Project rationale. This thesis investigates this and several alternative hypotheses and the ethical context related to their development. Firstly, the hypotheses are discussed in detail followed by a subsection in which research evidence based on each hypothesis is cited. Secondly, these medical genetics hypotheses are situated within the contemporary medical paradigm. To conclude, the thesis examines in depth the ethical and practical implications of medical genetics (...)
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  7. Jennifer Marshall & Trey Fitch (2001). Multiple Intelligence and Counselor Training. Inquiry 20 (3):26-32.
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