The N-Queens problem plays an important role in academic research and practical application. Heuristic algorithm is often used to solve variant 2 of the N-Queens problem. In the process of solving, evaluation of the candidate solution, namely, fitness function, often occupies the vast majority of running time and becomes the key to improve speed. In this paper, three parallel schemes based on CPU and four parallel schemes based on GPU are proposed, and a serial scheme is implemented at the baseline. (...) The experimental results show that, for a large-scale N-Queens problem, the coarse-grained GPU scheme achieved a maximum 307-fold speedup over a single-threaded CPU counterpart in evaluating a candidate solution. When the coarse-grained GPU scheme is applied to simulated annealing in solving N-Queens problem variant 2 with a problem size no more than 3000, the speedup is up to 9.3. (shrink)

Understanding the neural basis of schizophrenia (SZ) is important for shedding light on the neurobiological mechanisms underlying this mental disorder. Structural and functional alterations in the anterior cingulate cortex (ACC), dorsolateral prefrontal cortex (DLPFC), hippocampus, and medial prefrontal cortex (MPFC) have been implicated in the neurobiology of SZ. However, the effective connectivity among them in SZ remains unclear. The current study investigated how neuronal pathways involving these regions were affected in first-episode SZ using functional magnetic resonance imaging (fMRI). Forty-nine patients (...) with a first-episode of psychosis and diagnosis of SZ—according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision—were studied. Fifty healthy controls (HCs) were included for comparison. All subjects underwent resting state fMRI. We used spectral dynamic causal modeling (DCM) to estimate directed connections among the bilateral ACC, DLPFC, hippocampus, and MPFC. We characterized the differences using Bayesian parameter averaging (BPA) in addition to classical inference (t-test). In addition to common effective connectivity in these two groups, HCs displayed widespread significant connections predominantly involved in ACC not detected in SZ patients, but SZ showed few connections. Based on BPA results, SZ patients exhibited anterior cingulate cortico-prefrontal-hippocampal hyperconnectivity, as well as ACC-related and hippocampal-dorsolateral prefrontal-medial prefrontal hypoconnectivity. In summary, spectral DCM revealed the pattern of effective connectivity involving ACC in patients with first-episode SZ. This study provides a potential link between SZ and dysfunction of ACC, creating an ideal situation to associate mechanisms behind SZ with aberrant connectivity among these cognition and emotion-related regions. (shrink)

Improving the innovation ability of organizations is the focal point of management study. This paper puts forward that innovative self-efficacy and employees’ innovative behaviour are continuous mediating variables, and discusses the influence mechanism of employees’ involvement and open service innovation from the individual factor level. In this study, a sample of 103 employees from travel companies was used to examine the hypothesis. The results show that employee engagement is positively related to open service innovation. Innovative self-efficacy plays a completely intermediary (...) role between employee engagement and employee innovative behaviour; Creative self-efficacy and employees’ innovative behaviour play a continuous intermediary role between employees’ engagement and open service innovation. The results of this study will eventually help enterprises to carry out service innovation behaviour. (shrink)

ObjectiveTo investigate the attitudes of Chinese parents regarding the storage of dried blood spots collected for newborn screening (NBS) and their use in research.MethodsWe conducted a hospital-based survey of parents and examined parental attitudes regarding (a) allowing NBS sample storage, (b) permitting use of children’s NBS samples for research with parental permission, and (c) permitting use of children’s NBS samples for research without parental permission.ResultsThe response rate was 52 percent. Of parents surveyed, 68 percent would permit their infant’s NBS sample (...) to be stored for at least some length of time. If permission is obtained, 69 percent of parents “strongly agreed” or “agreed” to permit use of the NBS sample for research. If permission is not obtained, only 14 percent of parents “strongly agreed” or “agreed.” There was no significant association between permitting use of NBS samples for research and parental gender, education, household income, number of children, or site of residence.ConclusionsThis is the first survey of Chinese parents regarding the use of NBS samples for different types of research, with results indicating that most parents would permit their infant’s sample to be stored and would support the use of NBS dried blood spots for research purposes. (shrink)

BackgroundThe Basal ganglia (BG) played a crucial role in the brain-level mechanisms of chronic pain disorders. However, the functional changes of BG in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) are still poorly understood. This study investigated the BG subregions’ resting-state functional connectivity (rs-FC) in CP/CPPS patients compared with healthy controls.MethodsTwenty eight patients with CP/CPPS and 28 age- and education-matched healthy males underwent clinical measurements and 3T brain MR imaging, including T1-weighted structural images and resting-state functional imaging. The data were analyzed (...) by the seeded-based rs-FC analysis. Then, a machine learning method was applied to assess the feasibility of detecting CP/CPPS patients through the changed rs-FC.ResultsCompared with healthy males, patients presented decreased rs-FC between the BG subregions and right middle cingulate cortex, and correlated with pain (r = 0.51, p-uncorrected = 0.005) and urinary symptoms (r = –0.4, p-uncorrected = 0.034). The left superior temporal gyrus and right supramarginal gyrus showed decreased rs-FC with the BG subregions as well. The area under the receiver operating characteristic curve of 0.943 (accuracy = 80%, F1-score = 80.6%) was achieved for the classification of CP/CPPS patients and healthy males with support vector machine (SVM) based on the changed rs-FC.ConclusionThese findings provide evidence of altered BG subregions’ rs-FC in CP/CPPS, which may contribute to our understanding of the BG’s role in CP/CPPS. (shrink)

Higher education (HE) mobility programmes around the globe have been key initiatives over the past thirty years, driven by combinations of supranational and national state-led knowledge economy policies, university strategies, and decisions made by individuals regarding employability, credentials, or academic tourism. In this paper we argue that mobility too often is understood through the prism of internationalism, itself umbilically tied to and nourished by Enlightenment liberal thinking, such as Kantian cosmopolitanism, and the romantic figure of the wandering scholar. This has (...) the effect of reducing our understanding of transnational mobility to individual actors, their desires, and experiences. In this paper we ask: to what extent and in what ways can HE transnational mobility projects be understood as forms of imperialism? In this regard we examine the literature on imperialism and argue for a more capacious use of the term; as taking economic, political and cultural forms. We use these to examine the links between the expansion and securing of empires historically, the state’s spatial projects and global market making. We do this through the prism of two nations, the UK and China, comparing their state’s transnational HE strategies, selectivities and outcomes. (shrink)

Sun Yat-sen’s superior position in modern Chinese history is represented in the movement of the modernization of China with him as a representative went from the stage of ‘imitation’ to the stage of ‘creativity’. He put forward, China, as a country engaging in modernization late, could draw on Western experience and lessons, run (“突驾”) from capitalism directly into socialism, and realize ‘accomplishing both the political revolution and the social revolution at one stroke’. He designed the modernization program of ‘accomplishing both (...) at one stroke’ as the Three People's Principles (Nationalism, Democracy and the People's Livelihood); each separately connects with Human rights, civil rights and national sovereignty pursued by modern Chinese and the essence of them develops around the value of equality approved by socialist thoughts of the day. According to Sun’s thinking: 1. People’s livelihood is the root of the Three People'sPrinciples, which involves most primary human rights --- right of survival because the value of human’s seeking survival necessarily directs to ‘equality and helping each other’, which is the law of the evolution of humanity. So the justice of socialism lies in ‘Leveling out the differences between the rich and the poor’, which can be realized with many ‘artificial’ elements such as nation and morality, etc. What must be done by People’s livelihood in contemporary China are ‘equalizing landownership’, ‘regulating capital’ and ‘developing industry’. 2. Democracy is the request of ‘civil rights’ in the sense of modern democracy. In the special national situation of China, it presents itself as the specific political framework ‘balancing people’s civil rights with elite administration’. 3. The essence of nationalism lies in constructing modern Chinese national country to save the nation from crises. Sun Yat-sen pointed out: First, the foundation on which Chinese nations build up their country is totally different from that of the West. So the country must take ‘collectivism’ as its value direction. Secondly, the ethos of the Chinese nation is different from that of the West. Chinese national country must take ‘morality first’ as the direction of value. Sun’s point of view is unique and single-eyed but contains unavoidable historical limits. (shrink)

本书共分五个章节，依次为：一、竹简《文子》研究；二、竹简《文字》成书年代反思；三、竹简《文子》、进本《文字》、《淮南子》三书关系反思；四、今本《文子》与《淮南子》之关系；五、当代学者新近出版《文子》论 著评述。.

本书为作者近年最新论述的结集，主要论域为西方思想与历史哲学。收入论文30余篇，分为四辑：康德历史思想研究之专题；历史哲学之探讨；中西文化之交流；中国现代思想史之雪泥鸿爪。.

本书受教育部2004年哲学社会科学研究重大课题攻关项目“当代科学哲学的发展趋势研究”(04JZD0004)、国家社会科学基金项目“测量难题的模态解释——量子力学前沿中的哲学问题”(05CZX008)和 教育部人文社会科学重点研究基地——山西大学科学技术哲学研究中心基金资助.

Jian Zhou,* Weiqiang Ju,* Xiaopeng Yuan, Xiaofeng Zhu, Dongping Wang, Xiaoshun HeOrgan Transplant Center, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China *These authors contributed equally to this work: Hyperosmolar nonketotic hyperglycemic coma is a serious, rare complication induced by methylprednisolone pulse therapy for acute rejection after orthotopic liver transplantation. Herein, we report an unusual case of a 58-year-old woman who experienced acute rejection at 30 months after OLT, only one case in which HNKHC resulted in (...) MP pulse therapy for acute rejection in all 913 recipients in our center. The general morbidity of HNKHC was 1.09‰ in this study. HNKHC is characterized by rapid onset, rapid progression, and a lack of specific clinical manifestations. High-dose MP management was a clear risk factor. The principle of treatment included rapid rehydration, low-dose insulin infusion, and correcting disorders of electrolytes and acidosis. In conclusion, clinicians considering MP pulse therapy after OLT should be alert to the occurrence of HNKHC. Keywords: liver transplantation, complications, hyperosmolar nonketotic hyperglycemic coma, methylprednisolone pulse therapy, principle of treatment. (shrink)

本书是一部讨论“哲学理论创新与构建和谐社会关系”的文集,作者致力于发掘传统哲学资源,梳理和谐哲学思想的发展轨迹;对一些与生态和谐、社会和谐有关的现代哲学思潮进行评析;对辩证矛盾观的内涵进行反思,探讨了 构建和谐社会的思维方式与方法论。.

本文集收入“传统道德文化的继承与批判”、“中国传统文化的现代化意义”、“关于中国传统道德和文化的几个问题”等文章61篇。.

本书内容包括:和谐文化思想的历史探析、建设中国特色社会主义与和谐文化、现代化进程中的和谐文化建设、云南和谐文化建设的探索与实践。.

本书从美学角度对物理学所呈现的简单、对称、和谐之美作一历史性的介绍,并对物理学家的思维方式和发现模式作了具体的分析。.

本书针对当前文化现状中存在的问题,系统探讨了建设和谐文化五个方面的内容,并提出可操作的具体措施,以期对我国社会主义和谐文化建设的深入开展有所裨益。.

這是一本醫者的手札,道盡了生命的現實,記述著臨終或重病的現象和生命的極限,並揭示愛與珍惜生命的道理,除了對患病者本身在面臨驟變時的心態調適有幫助之外,也是與讀者做一番如何克服感情與生命的最痛的對話.

法学是春秋战国时期的一个主要学派。“法者,编著之图藉, 设之于官府, 而布之于百姓者也。”法家主张法、术、势的结合。法、指法律制度 ; 术, 指君王驾御群臣、掌握政权、推行法令的政策和手段 ; 势 ; 指君王的权势.

本书系“湖南省社会科学规划项目”、“湖南省教育厅青年项目”的研究成果。本书由“湖南科技大学学术著作出版基金”资助.