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Profile: John Dupre (University of Exeter)
  1.  39
    John Dupré (1993). The Disorder of Things: Metaphysical Foundations of the Disunity of Science. Harvard University Press.
  2. John Dupre (ed.) (1987). The Latest on the Best: Essays on Evolution and Optimality. MIT Press.
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  3.  22
    John Dupré (2001). Human Nature and the Limits of Science. Oxford University Press.
    John Dupre warns that our understanding of human nature is being distorted by two faulty and harmful forms of pseudo-scientific thinking. Not just in the academic world but in everyday life, we find one set of experts who seek to explain the ends at which humans aim in terms of evolutionary theory, while the other set uses economic models to give rules of how we act to achieve those ends. Dupre demonstrates that these theorists' explanations do not work and that, (...)
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  4.  42
    Maureen A. O’Malley & John Dupré (2007). Size Doesn't Matter: Towards a More Inclusive Philosophy of Biology. [REVIEW] Biology and Philosophy 22 (2):155-191.
    Philosophers of biology, along with everyone else, generally perceive life to fall into two broad categories, the microbes and macrobes, and then pay most of their attention to the latter. ‘Macrobe’ is the word we propose for larger life forms, and we use it as part of an argument for microbial equality. We suggest that taking more notice of microbes – the dominant life form on the planet, both now and throughout evolutionary history – will transform some of the philosophy (...)
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  5. Harold Kincaid, John Dupré & Alison Wylie (eds.) (2007). Value-Free Science?: Ideals and Illusions. Oxford University Press.
    It has long been thought that science is our best hope for realizing objective knowledge, but that, to deliver on this promise, it must be value free. Things are not so simple, however, as recent work in science studies makes clear. The contributors to this volume investigate where and how values are involved in science, and examine the implications of this involvement for ideals of objectivity.
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  6.  49
    John Dupré & Maureen O'malley (2009). Varieties of Living Things: Life at the Intersection of Lineage and Metabolism. Philosophy & Theory in Biology 1 (20130604).
    We address three fundamental questions: What does it mean for an entity to be living? What is the role of inter-organismic collaboration in evolution? What is a biological individual? Our central argument is that life arises when lineage-forming entities collaborate in metabolism. By conceiving of metabolism as a collaborative process performed by functional wholes, which are associations of a variety of lineage-forming entities, we avoid the standard tension between reproduction and metabolism in discussions of life – a tension particularly evident (...)
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  7.  31
    Maureen A. O'Malley & John Dupré (2005). Fundamental Issues in Systems Biology. Bioessays 27 (12):1270-1276.
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  8. John Dupré (1981). Natural Kinds and Biological Taxa. Philosophical Review 90 (1):66-90.
  9.  49
    Eric Bapteste & John Dupré (2013). Towards a Processual Microbial Ontology. Biology and Philosophy 28 (2):379-404.
    Standard microbial evolutionary ontology is organized according to a nested hierarchy of entities at various levels of biological organization. It typically detects and defines these entities in relation to the most stable aspects of evolutionary processes, by identifying lineages evolving by a process of vertical inheritance from an ancestral entity. However, recent advances in microbiology indicate that such an ontology has important limitations. The various dynamics detected within microbiological systems reveal that a focus on the most stable entities (or features (...)
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  10.  60
    John Dupré (2013). Living Causes. Aristotelian Society Supplementary Volume 87 (1):19-37.
    This paper considers the applicability of standard accounts of causation to living systems. In particular it examines critically the increasing tendency to equate causal explanation with the identification of a mechanism. A range of differences between living systems and paradigm mechanisms are identified and discussed. While in principle it might be possible to accommodate an account of mechanism to these features, the attempt to do so risks reducing the idea of a mechanism to vacuity. It is proposed that the solution (...)
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  11.  62
    John Dupré & Nancy Cartwright (1988). Probability and Causality: Why Hume and Indeterminism Don't Mix. Noûs 22 (4):521-536.
  12.  9
    Thomas Pradeu, Gladys Kostyrka & John Dupré, Understanding Viruses: Philosophical Investigations.
    Viruses have been virtually absent from philosophy of biology. In this editorial introduction, we explain why we think viruses are philosophically important. We focus on six issues, and we show how they relate to classic questions of philosophy of biology and even general philosophy.
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  13.  27
    Maureen O'Malley, Jane Calvert & John Dupré (2007). The Study of Socioethical Issues in Systems Biology. American Journal of Bioethics 7 (4):67-78.
    Systems biology is the rapidly growing and heavily funded successor science to genomics. Its mission is to integrate extensive bodies of molecular data into a detailed mathematical understanding of all life processes, with an ultimate view to their prediction and control. Despite its high profile and widespread practice, there has so far been almost no bioethical attention paid to systems biology and its potential social consequences. We outline some of systems biology's most important socioethical issues by contrasting the concept of (...)
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  14. John Dupré (2013). Elliott Sober Did Darwin Write the Origin Backwards? Philosophical Essays on Darwin's Theory. British Journal for the Philosophy of Science 64 (4):axt010.
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  15.  11
    Alexander Powell, Maureen A. O'Malley, Staffan Mueller-Wille, Jane Calvert & John Dupré (2007). Disciplinary Baptisms: A Comparison of the Naming Stories of Genetics, Molecular Biology, Genomics and Systems Biology. History and Philosophy of the Life Sciences 29 (1):5-32.
    Understanding how scientific activities use naming stories to achieve disciplinary status is important not only for insight into the past, but for evaluating current claims that new disciplines are emerging. In order to gain a historical understanding of how new disciplines develop in relation to these baptismal narratives, we compare two recently formed disciplines, systems biology and genomics, with two earlier related life sciences, genetics and molecular biology. These four disciplines span the twentieth century, a period in which the processes (...)
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  16.  35
    John Dupre (1988). Materialism, Physicalism, and Scientism. Philosophical Topics 16 (1):31-56.
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  17.  14
    John Dupré (1999). On the Impossibility of a Monistic Account of Species. In Robert A. Wilson (ed.), Species: New Interdisciplinary Essays. Bradford Books 3-22.
  18.  51
    Alexander Powell & John Dupré (2009). From Molecules to Systems: The Importance of Looking Both Ways. Studies in History and Philosophy of Biological and Biomedical Sciences 40 (1):54-64.
    Although molecular biology has meant different things at different times, the term is often associated with a tendency to view cellular causation as conforming to simple linear schemas in which macro-scale effects are specified by micro-scale structures. The early achievements of molecular biologists were important for the formation of such an outlook, one to which the discovery of recombinant DNA techniques, and a number of other findings, gave new life even after the complexity of genotype–phenotype
    relations had become apparent. Against this (...)
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  19.  51
    Maureen A. O’Malley, William Martin & John Dupré (2010). The Tree of Life: Introduction to an Evolutionary Debate. [REVIEW] Biology and Philosophy 25 (4):441-453.
    The ‘Tree of Life’ is intended to represent the pattern of evolutionary processes that result in bifurcating species lineages. Often justified in reference to Darwin’s discussions of trees, the Tree of Life has run up against numerous challenges especially in regard to prokaryote evolution. This special issue examines scientific, historical and philosophical aspects of debates about the Tree of Life, with the aim of turning these criticisms towards a reconstruction of prokaryote phylogeny and even some aspects of the standard evolutionary (...)
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  20.  16
    John Dupré & Maureen A. O'Malley (2007). Metagenomics and Biological Ontology. Studies in History and Philosophy of Science Part C 38 (4):834-846.
    Metagenomics is an emerging microbial systems science that is based on the large-scale analysis of the DNA of microbial communities in their natural environments. Studies of metagenomes are revealing the vast scope of biodiversity in a wide range of environments, as well as new functional capacities of individual cells and communities, and the complex evolutionary relationships between them. Our examination of this science focuses on the ontological implications of these studies of metagenomes and metaorganisms, and what they mean for common (...)
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  21.  47
    John Dupré (2002). Is 'Natural Kind' a Natural Kind Term? The Monist 85 (1):29-49.
  22.  31
    John Dupré (2014). Animalism and the Persistence of Human Organisms. Southern Journal of Philosophy 52 (S1):6-23.
    Humans are a kind of animal, and it is a natural and sensible idea that the way to understand what it is for a human person to persist over time is to reflect on what it is for an animal to persist. This paper accepts this strategy. However, especially in the light of a range of recent biological findings, the persistence of animals turns out to be much more problematic than is generally supposed. The main philosophical premise of the paper (...)
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  23.  7
    Alexander Powell, Maureen A. O. Malley, Staffan Muller-Wille, Jane Calvert & John Dupré (2007). Disciplinary Baptisms: A Comparison of the Naming Stories of Genetics, Molecular Biology, Genomics, and Systems Biology. History and Philosophy of the Life Sciences 29 (1):5.
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  24.  5
    John Dupré (forthcoming). Social Science City Center or Leafy Suburb. Philosophy of the Social Sciences:0048393116649713.
    This article argues, in opposition to a common interpretation of Wittgenstein deriving from Winch, that there is nothing especially problematic about the social sciences. Familiar Wittgensteinian theses about language, notably on the open-endedness of linguistic rules and on the importance of family resemblance concepts, have great relevance not only to the social sciences but also to much of the natural sciences. The differences between scientific and ordinary language are much less sharp than Winch, and probably Wittgenstein, supposed.
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  25.  31
    John Dupré (1999). Are Whales Fish. In D. Medin & S. Atran (eds.), Folkbiology. MIT Press 461--476.
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  26.  36
    John Dupré & Maureen A. O’Malley (2007). Metagenomics and Biological Ontology. Studies in History and Philosophy of Science Part C 38 (4):834-846.
    Metagenomics is an emerging microbial systems science that is based on the large-scale analysis of the DNA of microbial communities in their natural environments. Studies of metagenomes are revealing the vast scope of biodiversity in a wide range of environments, as well as new functional capacities of individual cells and communities, and the complex evolutionary relationships between them. Our examination of this science focuses on the ontological implications of these studies of metagenomes and metaorganisms, and what they mean for common (...)
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  27. John Dupré (2004). What's the Fuss About Social Constructivism. Episteme 1 (1):73-85.
    The topic of this paper is social constructivist doctrines about the nature of scientific knowledge. I don't propose to review all the many accounts that have either claimed this designation or had it ascribed to them. Rather I shall try to consider in a very general way what sense should be made of the underlying idea, and then illustrate some of the central points with two central examples from biology. The first thing to say is that, on the face of (...)
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  28.  35
    John Dupré (2004). Understanding Contemporary Genomics. Perspectives on Science 12 (3):320-338.
    : Recent molecular biology has seen the development of genomics as a successor to traditional genetics. This paper offers an overview of the structure, epistemology, and (very briefly) history of contemporary genomics. A particular focus is on the question to what extent the genome contains, or is composed of, anything that corresponds to traditional conceptions of genes. It is concluded that the only interpretation of genes that has much contemporary scientific relevance is what is described as the "developmental defect" gene (...)
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  29.  32
    John Dupre (2002). The Lure of the Simplistic. Philosophy of Science 69 (S3):S284-S293.
    This paper attacks the perennial philosophical and scientific quest for a simple and unified vision of the world. Without denying the attraction of this vision, I argue that such a goal often seriously distorts our understanding of complex phenomena. The argument is illustrated with reference to simplistic attempts to provide extremely general views of biology, and especially of human nature, through the theory of evolution. Although that theory is a fundamental ingredient of our scientific world view, it provides only one (...)
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  30.  7
    John Dupre (2004). Understanding Contemporary Genomics. Perspectives on Science 12 (3):320-338.
    Recent molecular biology has seen the development of genomics as a successor to traditional genetics. This paper offers an overview of the structure, epistemology, and history of contemporary genomics. A particular focus is on the question to what extent the genome contains, or is composed of, anything that corresponds to traditional conceptions of genes. It is concluded that the only interpretation of genes that has much contemporary scientific relevance is what is described as the "developmental defect" gene concept. However, developmental (...)
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  31.  30
    John Dupré (2011). Emerging Sciences and New Conceptions of Disease; or, Beyond the Monogenomic Differentiated Cell Lineage. European Journal for Philosophy of Science 1 (1):119-131.
    This paper will begin with some very broad and general considerations about the kind of biological entities we are. This exercise is motivated by the belief that the view of what we—multicellular eukaryotic organisms—are that is widely assumed by biologists, medical scientists and the general public, is an extremely limited one. It cannot be assumed a priori that a more sophisticated view will make a major difference to the science or practice of medicine, and there are areas of medicine to (...)
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  32.  2
    John Dupré & Maureen A. O'Malley (2009). Varieties of Living Things: Life at the Intersection of Lineage and Metabolism. Philosophy and Theory in Biology 1 (20160629).
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  33.  49
    John Dupré (2012). Comments onPhilosophy of Science After Feminism, by Janet Kourany. Perspectives on Science 20 (3):310-319.
  34.  19
    John Dupré (1998). Normal People. Social Research 65.
  35.  53
    John Dupré (2002). The Lure of the Simplistic. Proceedings of the Philosophy of Science Association 2002 (3):S284-S293.
    This paper attacks the perennial philosophical and scientific quest for a simple and unified vision of the world. Without denying the attraction of this vision, I argue that such a goal often seriously distorts our understanding of complex phenomena. The argument is illustrated with reference to simplistic attempts to provide extremely general views of biology, and especially of human nature, through the theory of evolution. Although that theory is a fundamental ingredient of our scientific world view, it provides only one (...)
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  36.  28
    John Dupré (2015). Natural Categories and Human Kinds: Classification in the Natural and Social Sciences, by Muhammad Ali Khalidi. Mind 124 (493):358-361.
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  37.  4
    John Dupré (2008). The Constituents of Life. Uitgeverij van Gorcum.
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  38.  72
    John Dupré (1983). The Disunity of Science. Mind 92 (367):321-346.
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  39.  20
    John Dupré (2004). The Myth Gene. The Philosophers' Magazine 25 (25):58-58.
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  40.  29
    John Dupré (1984). Probabilistic Causality Emancipated. Midwest Studies in Philosophy 9 (1):169-175.
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  41. John Dupré (1995). The Solution to the Problem of the Freedom of the Will. Noûs 30:385 - 402.
    It has notoriously been supposed that the doctrine of determinism conflicts with the belief in human freedom. Yet it is not readily apparent how indeterminism, the denial of determinism, makes human freedom any less problematic. It has sometimes been suggested that the arrival of quantum mechanics should immediately have solved the problem of free will and determinism. It was proposed, perhaps more often by scientists than by philosophers, that the brain would need only to be fitted with a device for (...)
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  42. John Dupré (2010). It is Not Possible to Reduce Biological Explanations to Explanations in Chemistry and/or Physics. In Francisco José Ayala & Robert Arp (eds.), Contemporary Debates in Philosophy of Biology. Wiley-Blackwell Pub.
  43.  81
    John Dupré (2012). A Fine Book, but Who's It For? Metascience 21 (1):175-177.
  44.  8
    Alexander Powell & John Dupré (2009). From Molecules to Systems: The Importance of Looking Both Ways. Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 40 (1):54-64.
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  45.  12
    Maureen A. O'Malley & John Dupré (2007). Towards a Philosophy of Microbiology. Studies in History and Philosophy of Science Part C 38 (4):775-779.
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  46. John Dupré (2004). The Miracle of Monism. In Mario De Caro & David Macarthur (eds.), Naturalism in Question. Harvard University Press 36--58.
    This chapter defends a pluralistic view of science: the various projects of enquiry that fall under the general rubric of science share neither a methodology nor a subject matter. Ontologically, it is argued that sciences need have nothing in common beyond an antipathy to the supernatural. Epistemically one central virtue is defended, empiricism, meaning just that scientific knowledge must ultimately be answerable to experience. Prima facie science is as diverse as the world it studies; and rejection of this prima facie (...)
     
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  47.  54
    John Dupré (1983). Human Reproduction and Sociobiology. Analysis 43 (4):210 - 212.
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  48.  38
    John Dupré (2005). Are There Genes? Royal Institute of Philosophy Supplement 80 (56):16-.
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  49.  24
    John Dupré (1986). Sex, Gender, and Essence. Midwest Studies in Philosophy 11 (1):441-457.
  50.  61
    John Dupré (2010). The Human Genome, Human Evolution, and Gender. Constellations 17 (4):540-548.
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