The application of neuroimaging technology to the study of the injured brain has transformed how neuroscientists understand disorders of consciousness, such as the vegetative and minimally conscious states, and deepened our understanding of mechanisms of recovery. This scientific progress, and its potential clinical translation, provides an opportunity for ethical reflection. It was against this scientific backdrop that we convened a conference of leading investigators in neuroimaging, disorders of consciousness and neuroethics. Our goal was to develop an ethical frame to move (...) these investigative techniques into mature clinical tools. This paper presents the recommendations and analysis of a Working Meeting on Ethics, Neuroimaging and Limited States of Consciousness held at Stanford University during June 2007. It represents an interdisciplinary approach to the challenges posed by the emerging use of neuroimaging technologies to describe and characterize disorders of consciousness. (shrink)
The central question in this book is why it seems reasonable for the words of our language to divide up the world in ordinary ways rather than other imaginable ways. Hirsch calls this the division problem. His book aims to bring this problem into sharp focus, to distinguish it from various related problems, and to consider the best prospects for solving it. In exploring various possible responses to the division problem, Hirsch examines series of "division principles" which purport (...) to express rational constraints on how our words ought to classify and individuate. The ensuing discussion deals with a wide range of metaphysical and epistemological topics, including projectibility and similarity, alternative analyses of natural properties and things, the inscrutability of reference, and the relevance of such pragmatic notions as salience and economy. The final chapters of the book develop what Hirsch contends is the most promising response to the division problem: a theory in which constraints on classification and individuation are seen to derive from the necessary structure of "fine-grained" propositions and the necessary dependence of some concepts on others. (shrink)
Perhaps our most insightful thinker on what schools teach, E. D. Hirsch, Jr., shows why American students--beginning with a fourth-grade slump--perform less well than students in other industrialized countries. Drawing on classroom observation, the history of ideas, and current scientific understanding of the patterns of intellectual growth, Hirsch builds the case that our schools have indeed made progress in teaching the mechanics of reading. But, as he brilliantly shows, they fail virtually all American children--poor and middle class, in (...) public and private schools--because they do not convey the more complex and essential content needed for reading comprehension. Hirsch powerfully reasons that literacy depends less on formal reading "skills" and more on exposure to rich knowledge. It"s a compelling argument that gives parents specific tools for enhancing their child"s ability to read with comprehension shows how No-Child-Left-Behind tests and SATs are measuring certain kinds of knowledge--knowledge that is not being taught in our schools maps out how American schools can become a strong antidote to poverty and to our frustrating race-based achievement gap, and thus fulfill our democratic ideal for the schools and for our children. (shrink)
Scholars in the early seventeenth century who studied ancient Greek scientific theories often drew upon philology and history to reconstruct a more general picture of the Greek past. Gassendi's training as a humanist historiographer enabled him to formulate a conception of the history of philosophy in which the rationality of scientific and philosophical inquiry depended on the historical justifications which he developed for his beliefs. Professor Joy examines this conception and analyzes the nature of Gassendi's historical training, especially its relationship (...) to his career as a physicist and astronomer. She shows how he rehabilitated Epicurean atomism by bringing together the arguments of the Greek atomists and those of his contemporaries. In doing so, he produced an account of the natural world which made it an object of empirical study and mechanical explanation. (shrink)
Two main claims are defended in this paper: first, that typical disputes in the literature about the ontology of physical objects are merely verbal; second, that the proper way to resolve these disputes is by appealing to common sense or ordinary language. A verbal dispute is characterized not in terms of private idiolects, but in terms of different linguistic communities representing different positions. If we imagine a community that makes Chisholm's mereological essentialist assertions, and another community that makes Lewis's four-dimensionalist (...) assertions, the members of each community speak the truth in their respective languages. This follows from an application of the principle of interpretive charity to the two communities. (shrink)
A sense of unity -- Basic objects : a reply to Xu -- Objectivity without objects -- The vagueness of identity -- Quantifier variance and realism -- Against revisionary ontology -- Comments on Theodore Sider's four dimensionalism -- Sosa's existential relativism -- Physical-object ontology, verbal disputes, and common sense -- Ontological arguments : interpretive charity and quantifier variance -- Language, ontology, and structure -- Ontology and alternative languages.
Conflicts of interest are common and exist in academia, government, and many industries, including pharmaceutical development. Medical journal editors and others have recently criticized “the pharmaceutical industry,” citing concerns over investigator access to data, approaches to analysis of clinical trial data, and publication practices. Merck & Co., Inc. is a global, research-driven pharmaceutical company that discovers, develops, manufactures, and markets a broad range of human and animal health products, directly and through its joint ventures. Although part of its mission is (...) to provide a superior rate of return to its investors, Merck does not believe this creates an irreconcilable conflict of interest, particularly in activities concerning clinical drug development. We employ rigorous scientific methods to design, conduct, analyze, and report results of clinical trials in the development of innovative drugs and vaccines, with a focus on meeting unmet medical needs and with an ethic that puts the interests of the patient first. This article describes Merck’s approaches to potential conflicts of interest in drug development, particularly with regard to clinical trials. We believe that proprietary interests of the Company can be respected while observing objectivity and transparency in communicating clinical research results. The standards for the review of manuscripts reporting such trials for peer-reviewed publication should be the same, whether they are from Merck or elsewhere. (shrink)
Alliances and other forms of cooperation between firms often promise great benefits, for example, by the exchange of knowledge or co-specialization of resources. At the same time, the necessary actions to realize these benefits can augment vulnerability to opportunistic behaviour of partners. In addition to formal contracts to mitigate the resulting behavioural uncertainties, often, mechanisms, such as reputation or ethical values, are suggested as important supplements. However, when it comes to assessment of a specific cooperation opportunity, it is difficult to (...) account systematically for the economic consequences of these 'softer factors'. Therefore, this paper aims to surpass mere financial analysis of chance and risk and to integrate systematically both reputation and ethical values into an economic assessment of cooperative relationships. For this purpose, we develop a theoretical framework that is based on a simple-decision model to account for reputation and ethical values of potential partners as drivers of behavioural uncertainty reduction. We also discuss how this framework can be used to assess cooperative relationships and illustrate these ideas with reference to the inter-organizational accounting practices of a large drugstore chain and its suppliers. (shrink)
We can describe languages in which no words refer to objects. Such languages may contain sentences equivalent to any sentences of English, and hence may allow for as much objectivity as English does. It is wrong to try to deal with such languages by claiming that there are more objects than those accepted by common sense ontology. The correct move is rather to acknowledge a sense in which the concept of an object might have been different. A consequence of this (...) position is that we cannot have a general semantics applicable to every describable language in which words are referentially connected to objects. The point here is not that reference may be inscrutable, but that different concepts of ‘referring to an object’ may be required for different languages. (shrink)
The theme of gender in religion has not been dealt with homogenously given the many research areas that feed into the discipline of religious studies. This paper reviews the different uses of "gender" over the last 20 years. It notes that, though there is no single definition of the word, "gender" as a term has had a very great impact on the way women have formulated their demand for equality of treatment and renegotiated or even raised new claims as regards (...) their integrity and identity. (shrink)
The encounter occurred aboard the presidential yacht USS Potomac, the same steel-hulled craft that, half a century ago, carried Roosevelt to his meeting with Churchill wherein they secretly plotted World War II. It cruised on the San Francisco Bay as helicopters hovered above, dropping smoke flares to mark a jumper from the Golden Gate Bridge.
We confirm a conjecture, about neat embeddings of cylindric algebras, made in 1969 by J. D. Monk, and a later conjecture by Maddux about relation algebras obtained from cylindric algebras. These results in algebraic logic have the following consequence for predicate logic: for every finite cardinal α ≥ 3 there is a logically valid sentence X, in a first-order language L with equality and exactly one nonlogical binary relation symbol E, such that X contains only 3 variables (each of which (...) may occur arbitrarily many times), X has a proof containing exactly α + 1 variables, but X has no proof containing only α variables. This solves a problem posed by Tarski and Givant in 1987. (shrink)
Bernard Lonergan's cognitive theory challenges us to raise questions about both the cognitive process through which obesity is perceived as a behaviour change issue and the objectivity of such a moral judgment. Lonergan's theory provides the theoretical tools to affirm that anti-fat discrimination, in the United States of America and in many industrialized countries, is the result of both a group bias that resists insights into the good of other groups and a general bias of anti-intellectualism that tends to set (...) common sense against insights that require any thorough scientific analyses. While general bias diverts the public's attention away from the true aetiology of obesity, group bias sustains an anti-fat culture that subtly legitimates discriminatory practices and policies against obese people. Although anti-discrimination laws may seem to be a reasonable way of protecting obese and overweight individuals from discrimination, obesity bias can be best addressed by reframing the obesity debate from an environmental perspective from which tools and strategies to address both the social and individual determinants of obesity can be developed. Attention should not be concentrated on individuals' behaviour as it is related to lifestyle choices, without giving due consideration to the all-encompassing constraining factors which challenge the social and rational blindness of obesity bias. (shrink)
The Hospital of the Rockefeller Institute for Medical Research in New York City was founded on the hypothesis that direct contact with illness is a strong force in igniting the curiosity and energy that can, from time to time, lead to great leaps in our understanding of human biology and disease. This was repeatedly proven at the Hospital, a special locale where the “prepared minds” of physicians uncovered new facts that often led to effective treatments. It is neither a hospital (...) nor a laboratory, but a hospital-laboratory, which celebrated its 100th birthday in 2010. Although this was a first for America, the idea had been in the minds of European and British physician-investigators from the late 19th .. (shrink)
For every finite n ≥ 4 there is a logically valid sentence φ n with the following properties: φ n contains only 3 variables (each of which occurs many times); φ n contains exactly one nonlogical binary relation symbol (no function symbols, no constants, and no equality symbol): φ n has a proof in first-order logic with equality that contains exactly n variables, but no proof containing only n - 1 variables. This result was first proved using the machinery of (...) algebraic logic developed in several research monographs and papers. Here we replicate the result and its proof entirely within the realm of (elementary) first-order binary predicate logic with equality. We need the usual syntax, axioms, and rules of inference to show that φ n has a proof with only n variables. To show that φ n has no proof with only n - 1 variables we use alternative semantics in place of the usual, standard, set-theoretical semantics of first-order logic. (shrink)
We examined participants' reading and recall of informed consent documents presented via paper or computer. Within each presentation medium, we presented the document as a continuous or paginated document to simulate common computer and paper presentation formats. Participants took slightly longer to read paginated and computer informed consent documents and recalled slightly more information from the paginated documents. We concluded that obtaining informed consent online is not substantially different than obtaining it via paper presentation. We also provide suggestions for improving (...) informed consent-in both face-to-face and online experiments. (shrink)
Bernard Lonergan's cognitive theory challenges us to raise questions about both the cognitive process through which obesity is perceived as a behaviour change issue and the objectivity of such a moral judgment. Lonergan's theory provides the theoretical tools to affirm that anti-fat discrimination, in the United States of America and in many industrialized countries, is the result of both a group bias that resists insights into the good of other groups and a general bias of anti-intellectualism that tends to set (...) common sense against insights that require any thorough scientific analyses. While general bias diverts the public's attention away from the true aetiology of obesity, group bias sustains an anti-fat culture that subtly legitimates discriminatory practices and policies against obese people. Although anti-discrimination laws may seem to be a reasonable way of protecting obese and overweight individuals from discrimination, obesity bias can be best addressed by reframing the obesity debate from an environmental perspective from which tools and strategies to address both the social and individual determinants of obesity can be developed. Attention should not be concentrated on individuals' behaviour as it is related to lifestyle choices, without giving due consideration to the all-encompassing constraining factors which challenge the social and rational blindness of obesity bias. (shrink)
Hannah Arendt’s work on violence is bedeviled by a series of paradoxes. On the one hand, Arendt is clear in arguing that violence is utterly powerless and yet, on the other hand, she is equally clear in her portrayal of beginnings as necessarily violent. These two positions conflict insofar as Arendt holds beginnings to be the source of all power. Thus power and violence are at once opposed and yet alloyed. This tension is deepened by yet another. For Arendt, action, (...) of which power is composed, would not be possible without the twofold human faculties of promising and forgiveness. Promising undoes the hold of the future on the present by pacifying its unpredictability, while forgiveness loosens the grip of the past by alleviating its irreversibility. The trouble, however, is that Arendt argues that the power of forgiveness stems from its unpredictability, and unpredictability is precisely that which promising is meant to thwart. Taking these two paradoxes together one might say that Arendt, however unwittingly, leaves us promising never to forgive. This article works to flesh these paradoxes out. It also contextualizes Arendt’s paradoxes in terms of the literature that claims democratic political life is beset by tragedy. In the end, I argue that, following Arendt, democracy is ultimately about learning to live with the vivid disquiet of the miracle of paradox. (shrink)
A boolean algebra is shown to be completely representable if and only if it is atomic, whereas it is shown that neither the class of completely representable relation algebras nor the class of completely representable cylindric algebras of any fixed dimension (at least 3) are elementary.
We prove that every n-modal logic between K n and S5 n is undecidable, whenever n ≥ 3. We also show that each of these logics is non- finitely axiomatizable, lacks the product finite model property, and there is no algorithm deciding whether a finite frame validates the logic. These results answer several questions of Gabbay and Shehtman. The proofs combine the modal logic technique of Yankov-Fine frame formulas with algebraic logic results of Halmos, Johnson and Monk, and give a (...) reduction of the (undecidable) representation problem of finite relation algebras. (shrink)
Rose's accomplishment in combining ontological unity with epistemological diversity contrasts it with Wilson's failure in overemphasizing the former and not appreciating the latter. This commentary cites the two most authoritative discussions of the inapplicability of heritability to human data, corrects several historical errors or inaccuracies in genetics, and criticizes the characterizations of Jacques Loeb and Robert Plomin.
We consider the problem of finding and classifying representations in algebraic logic. This is approached by letting two players build a representation using a game. Homogeneous and universal representations are characterized according to the outcome of certain games. The Lyndon conditions defining representable relation algebras (for the finite case) and a similar schema for cylindric algebras are derived. Finite relation algebras with homogeneous representations are characterized by first order formulas. Equivalence games are defined, and are used to establish whether an (...) algebra is ω-categorical. We have a simple proof that the perfect extension of a representable relation algebra is completely representable. An important open problem from algebraic logic is addressed by devising another two-player game, and using it to derive equational axiomatisations for the classes of all representable relation algebras and representable cylindric algebras. Other instances of this approach are looked at, and include the step by step method. (shrink)
Morny Joy (2009). In Search of Wisdom. In John Cornwell & Michael McGhee (eds.), Philosophers and God: At the Frontiers of Faith and Reason. Continuum.score: 30.0
Joy is often mentioned in discussion of theories of hedonism, happiness, desire, or religion, but is rarely considered in itself. Consequently, much about the nature of joy remains unclear. Is it, for example, a distinctive state? A feeling? An emotion? Why is it experienced? Does it have a functional role? Through discussion of joy's nature, role, and importance, it will be demonstrated that joy can indeed be defined: as an intense, positively-valenced emotion, whose inherent connection to the desire for self-preservation (...) renders it inappropriate for providing the basis for theories of morality. (shrink)
