The rationale for pesticide use in agriculture is that costs associated with pesticide pollution are to be justified by its benefits, but this is not so obvious. Valuing the benefits by simple economic analysis has increased pesticide use in agriculture and consequently produced pesticide-induced public ills. This paper attempts to explore the research gaps of the economic and social consequences of pesticide use in developing countries, particularly with an example of Nepal. We argue that although the negative sides of agricultural (...) development, for example- soil, water, and air pollution; pest resistance and resurgence; bioaccumulation, bio-magnification; and loss of biodiversity and ecosystem resilience caused by the use of pesticides in agriculture, are developmental problems and are unintentional, the magnitude may be increased by undervaluing the problems in the analysis of its economic returns. Despite continuous effort for holistic system analyses for studying complex phenomena like pesticides impacts, the development within the academic science has proceeded in the opposite direction that might have accelerated marginalization of the third world subsistence agricultural communities. We hypothesize that, if these adversities are realized and accounted for, the benefits from the current use of pesticides could be outweighed by the costs of pollution and ill human health. This paper also illustrates different pathways and mechanisms for marginalization. In view of potential and overall negative impacts of pesticide use, we recommend alternative ways of controlling pests such as community integrated pest management (IPM) along with education and training activities. Such measures are likely to reduce the health and environmental costs of pesticide pollution, and also enhance the capabilities of third world agricultural communities in terms of knowledge, decision making, innovation, and policy change. (shrink)
The rationale for pesticide use in agriculture is that costs associated with pesticide pollution are to be justified by its benefits, but this is not so obvious. Valuing the benefits by simple economic analysis has increased pesticide use in agriculture and consequently produced pesticide-induced “public ills.” This paper attempts to explore the research gaps of the economic and social consequences of pesticide use in developing countries, particularly with an example of Nepal. We argue that although the negative sides of agricultural (...) development, for example- soil, water, and air pollution; pest resistance and resurgence; bioaccumulation, bio-magnification; and loss of biodiversity and ecosystem resilience caused by the use of pesticides in agriculture, are “developmental problems” and are “unintentional,” the magnitude may be increased by undervaluing the problems in the analysis of its economic returns. Despite continuous effort for holistic system analyses for studying complex phenomena like pesticides impacts, the development within the academic science has proceeded in the opposite direction that might have accelerated marginalization of the third world subsistence agricultural communities. We hypothesize that, if these adversities are realized and accounted for, the benefits from the current use of pesticides could be outweighed by the costs of pollution and ill human health. This paper also illustrates different pathways and mechanisms for marginalization. In view of potential and overall negative impacts of pesticide use, we recommend alternative ways of controlling pests such as community integrated pest management (IPM) along with education and training activities. Such measures are likely to reduce the health and environmental costs of pesticide pollution, and also enhance the capabilities of third world agricultural communities in terms of knowledge, decision making, innovation, and policy change. (shrink)
If rapid growth (rap) mutants of Escherichia coli could be obtained, these might prove a valuable contribution to fields as diverse as growth rate control, biotechnology and the regulation of the bacterial cell cycle. To obtain rap mutants, a dnaQ mutator strain was grown for four and a half days continuously in batch culture. At the end of the selection period, there was no significant change in growth rate. This result means that selecting rap mutants may require an alternative strategy (...) and a number of such alternatives are discussed. (shrink)
Almost all ethical guidelines and legislative policies concerning biomedical research involving human subjects contain provisions about relevance of research for the participating populations, informed consent, adequate care for research induced injuries and several other safeguards but the poor continue to suffer. Globalization has further aggravated poor people’s vulnerability by exposing them to international markets. Since the developing countries are abode of higher population of the poor they have become the unholy mines of this human ore for researchers. In this paper (...) I examine various dimensions of poverty and analyze the international ethical responses in the area of biomedical research involving human subjects in order to determine their adequacy to protect the poor against exploitation and misuse and conclude that in view of the poor’s inherent and extreme vulnerability and the failure of ethical pronouncements to protect them from misuse and exploitation, they should be excluded from being enrolled as research subjects. (shrink)
In this unique monograph, based on years of extensive work, Chatterjee presents the historical evolution of statistical thought from the perspective of various approaches to statistical induction. Developments in statistical concepts and theories are discussed alongside philosophical ideas on the ways we learn from experience. -/- Suitable for researchers, lecturers and students in statistics and the history of science this book is aimed at those who have had some exposure to statistical theory. It is also useful to logicians and philosophers (...) due to the discussion of the problem of statistical induction in a wider philosophical context and the impact of developments of statistics on current thinking -/- The book is divided into two parts: -/- Part I (Chapters 1-4) entitled 'Perspective' deals with foundations and structure and Part II (Chapters 5-10), explores the 'History'. In Chapter 1 statistics is characterized as 'prolongation of induction', and its philosophical background is briefly reviewed. The special features of statistical induction, the two roles (as input and output) the theory of probability plays in it, and the different interpretations of probability are discussed in the next two chapters. Chapter 4 distinguishes broadly between four different approaches to statistical induction (behavioural, instantial, pro-subjective Bayesian, and purely subjective) that have been developed by taking different interpretations of probability as input and output, and considers their comparative characteristics, advantages and disadvantages . Part II traces the historical evolution of statistical thought in the perspective of the framework described in Part I and specifically considers the origin and development of the different concepts of probability and their application to the formulation of the different approaches to statistical induction. After some reference to the prehistory of the subject, the contributions made by the principal contributors in probability and statistics in the 17th-20th centuries are outlined (beginning with Cardano, Pascal, Fermat, Huygens and James Bernoulli and proceeding through Laplace and Gauss to Karl Pearson, Fisher, Neyman, E.S.Pearson,Wald, and their successors). Throughout, the emphasis is on concepts - factual details and technicalities are introduced only if they are unavoidable. (shrink)
