You are accessing PhilPapers from Open University (UK), an institution that is not subscribed to PhilPapers. Starting on July 1, 2014, we ask institutions that grant philosophy degrees and are based in high-GDP countries to contribute to PhilPapers' maintenance and development through a subscription. See this page for details. Please show your support by contacting your librarian.
6 found
Sort by:
  1. Larry Wasserman, Evidence of Systematic Expressed Sequence Tag IMAGE Clone Cross-Hybridization on cDNA Microarrays.
    We present evidence of a potentially serious source of error intrinsic to all spotted cDNA microarrays that use IMAGE clones of expressed sequence tags (ESTs). We found that a high proportion of these EST sequences contain 5V-end poly(dT) sequences that are remnants from the oligo(dT)-primed reverse transcription of polyadenylated mRNA templates used to generate EST cDNA for sequence clone libraries. Analysis of expression data from two single-dye cDNA microarray experiments showed that ESTs whose sequences contain repeats of consecutive 5V- end (...)
    No categories
    Direct download (3 more)  
     
    My bibliography  
     
    Export citation  
  2. Nicoleta Serban, Larry Wasserman, David Peters, Peter Spirtes, Robert O'Doherty, Daniel Handley, Richard Scheines & Clark Glymour, Analysis of Microarray Data for Treated Fat Cells.
    DNA microarrays are perfectly suited for comparing gene expression in different populations of cells. An important application of microarray techniques is identifying genes which are activated by a particular drug of interest. This process will allow biologists to identify therapies targeted to particular diseases, and, eventually, to gain more knowledge about the biological processes in organisms. Such an application is described in this paper. It is focused on diabetes and obesity, which is a genetically heterogeneous disease, meaning that multiple defective (...)
    No categories
    Direct download (2 more)  
     
    My bibliography  
     
    Export citation  
  3. James M. Robins, Richard Scheines, Peter Spirtes & Larry Wasserman, The Limits of Causal Knowledge.
    James M. Robins, Richard Scheines, Peter Spirtes, and Larry Wasserman. The Limits of Causal Knowledge.
    No categories
    Direct download (2 more)  
     
    My bibliography  
     
    Export citation  
  4. Timothy Herron, Teddy Seidenfeld & Larry Wasserman (1997). Divisive Conditioning: Further Results on Dilation. Philosophy of Science 64 (3):411-444.
    Conditioning can make imprecise probabilities uniformly more imprecise. We call this effect "dilation". In a previous paper (1993), Seidenfeld and Wasserman established some basic results about dilation. In this paper we further investigate dilation on several models. In particular, we consider conditions under which dilation persists under marginalization and we quantify the degree of dilation. We also show that dilation manifests itself asymptotically in certain robust Bayesian models and we characterize the rate at which dilation occurs.
    Direct download (6 more)  
     
    My bibliography  
     
    Export citation  
  5. Timothy Herron, Teddy Seidenfeld & Larry Wasserman (1994). The Extent of Dilation of Sets of Probabilities and the Asymptotics of Robust Bayesian Inference. PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association 1994:250 - 259.
    We report two issues concerning diverging sets of Bayesian (conditional) probabilities-divergence of "posteriors"-that can result with increasing evidence. Consider a set P of probabilities typically, but not always, based on a set of Bayesian "priors." Fix E, an event of interest, and X, a random variable to be observed. With respect to P, when the set of conditional probabilities for E, given X, strictly contains the set of unconditional probabilities for E, for each possible outcome X = x, call this (...)
    Direct download (2 more)  
     
    My bibliography  
     
    Export citation  
  6. Larry Wasserman (1992). Comments on Shafer's``Perspectives on the Theory and Practice of Belief Functions''. International Journal of Approximate Reasoning 6 (2):367--375.
    Translate to English
    |
     
    My bibliography  
     
    Export citation