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Profile: Laurence McCullough (Baylor College of Medicine)
  1.  16
    Laurence B. McCullough & Frank A. Chervenak (2011). An Ethically Justified Framework for Clinical Investigation to Benefit Pregnant and Fetal Patients. American Journal of Bioethics 11 (5):39-49.
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  2.  82
    Laurence B. McCullough (1998). Molecular Medicine, Managed Care, and the Moral Responsibilities of Patients and Physicians. Journal of Medicine and Philosophy 23 (1):3 – 9.
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  3.  21
    Robert L. Brent, Frank A. Chervenak, Laurence B. McCullough & Benjamin Hippen (2010). A Case Study in Unethical Transgressive Bioethics: “Letter of Concern From Bioethicists” About the Prenatal Administration of Dexamethasone. American Journal of Bioethics 10 (9):35-45.
    On February 3, 2010, a “Letter of Concern from Bioethicists,” organized by fetaldex.org, was sent to report suspected violations of the ethics of human subjects research in the off-label use of dexamethasone during pregnancy by Dr. Maria New. Copies of this letter were submitted to the FDA Office of Pediatric Therapeutics, the Department of Health and Human Services (DHHS) Office for Human Research Protections, and three universities where Dr. New has held or holds appointments. We provide a critical appraisal of (...)
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  4.  23
    Aanand D. Naik, Carmel B. Dyer, Mark E. Kunik & Laurence B. McCullough (2009). Patient Autonomy for the Management of Chronic Conditions: A Two-Component Re-Conceptualization. American Journal of Bioethics 9 (2):23 – 30.
    The clinical application of the concept of patient autonomy has centered on the ability to deliberate and make treatment decisions (decisional autonomy) to the virtual exclusion of the capacity to execute the treatment plan (executive autonomy). However, the one-component concept of autonomy is problematic in the context of multiple chronic conditions. Adherence to complex treatments commonly breaks down when patients have functional, educational, and cognitive barriers that impair their capacity to plan, sequence, and carry out tasks associated with chronic care. (...)
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  5.  28
    Laurence B. Mccullough (2011). Was Bioethics Founded on Historical and Conceptual Mistakes About Medical Paternalism? Bioethics 25 (2):66-74.
    Bioethics has a founding story in which medical paternalism, the interference with the autonomy of patients for their own clinical benefit, was an accepted ethical norm in the history of Western medical ethics and was widespread in clinical practice until bioethics changed the ethical norms and practice of medicine. In this paper I show that the founding story of bioethics misreads major texts in the history of Western medical ethics. I also show that a major source for empirical claims about (...)
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  6.  15
    Laurence B. McCullough & Frank A. Chervenak (2008). A Critical Analysis of the Concept and Discourse of 'Unborn Child'. American Journal of Bioethics 8 (7):34 – 39.
    Despite its prominence in the abortion debate and in public policy, the discourse of 'unborn patient' has not been subjected to critical scrutiny. We provide a critical analysis in three steps. First, we distinguish between the descriptive and normative meanings of 'unborn child.' There is a long history of the descriptive use of 'unborn child.' Second, we argue that the concept of an unborn child has normative content but that this content does not do the work that opponents of abortion (...)
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  7.  10
    Benjamin Hippen, Robert L. Brent, Frank A. Chervenak & Laurence B. McCullough (2010). A Case Study in Unethical Transgressive Bioethics: “Letter of Concern From Bioethicists” About the Prenatal Administration of Dexamethasone. American Journal of Bioethics 10 (9):35-45.
    On February 3, 2010, a “Letter of Concern from Bioethicists,” organized by fetaldex.org, was sent to report suspected violations of the ethics of human subjects research in the off-label use of dexamethasone during pregnancy by Dr. Maria New. Copies of this letter were submitted to the FDA Office of Pediatric Therapeutics, the Department of Health and Human Services (DHHS) Office for Human Research Protections, and three universities where Dr. New has held or holds appointments. We provide a critical appraisal of (...)
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  8.  18
    Simon N. Whitney & Laurence B. McCullough (2007). Physicians' Silent Decisions: Because Patient Autonomy Does Not Always Come First. American Journal of Bioethics 7 (7):33 – 38.
    Physicians make some medical decisions without disclosure to their patients. Nondisclosure is possible because these are silent decisions to refrain from screening, diagnostic or therapeutic interventions. Nondisclosure is ethically permissible when the usual presumption that the patient should be involved in decisions is defeated by considerations of clinical utility or patient emotional and physical well-being. Some silent decisions - not all - are ethically justified by this standard. Justified silent decisions are typically dependent on the physician's professional judgment, experience and (...)
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  9. Laurence B. Mccullough (1998). John Gregory and the Invention of Professional Medical Ethics and Profession of Medicine.
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  10.  17
    Laurence B. McCullough, John H. Coverdale & Frank A. Chervenak (2007). Constructing a Systematic Review for Argument-Based Clinical Ethics Literature: The Example of Concealed Medications. Journal of Medicine and Philosophy 32 (1):65 – 76.
    The clinical ethics literature is striking for the absence of an important genre of scholarship that is common to the literature of clinical medicine: systematic reviews. As a consequence, the field of clinical ethics lacks the internal, corrective effect of review articles that are designed to reduce potential bias. This article inaugurates a new section of the annual "Clinical Ethics" issue of the Journal of Medicine and Philosophy on systematic reviews. Using recently articulated standards for argument-based normative ethics, we provide (...)
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  11.  34
    Robert Baker & Laurence B. McCullough (2007). Medical Ethics' Appropriation of Moral Philosophy: The Case of the Sympathetic and the Unsympathetic Physician. Kennedy Institute of Ethics Journal 17 (1):3-22.
    Philosophy textbooks typically treat bioethics as a form of "applied ethics"-i.e., an attempt to apply a moral theory, like utilitarianism, to controversial ethical issues in biology and medicine. Historians, however, can find virtually no cases in which applied philosophical moral theory influenced ethical practice in biology or medicine. In light of the absence of historical evidence, the authors of this paper advance an alternative model of the historical relationship between philosophical ethics and medical ethics, the appropriation model. They offer two (...)
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  12. Frederick Grinnell, Jeffrey P. Bishop & Laurence B. McCullough (2002). Bioethical Pluralism and Complementarity. Perspectives in Biology and Medicine 45 (3):338-349.
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  13. Robert Baker & Laurence B. McCullough (eds.) (2009). The Cambridge World History of Medical Ethics. Cambridge University Press.
    The Cambridge World History of Medical Ethics is the first comprehensive scholarly account of the global history of medical ethics. Offering original interpretations of the field by leading bioethicists and historians of medicine, it will serve as the essential point of departure for future scholarship in the field. The volumes reconceptualize the history of medical ethics through the creation of new categories, including the life cycle; discourses of religion, philosophy, and bioethics; and the relationship between medical ethics and the state, (...)
     
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  14.  5
    Laurence B. McCullough, Frank A. Chervenak & Susan M. Scott (1995). Ethics in Obstetrics and Gynecology. HEC Forum 7 (6):379-380.
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  15.  1
    Laurence B. McCullough (2015). Professionally Responsible Clinical Ethical Judgments of Futility. American Journal of Bioethics 15 (8):54-56.
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  16.  4
    Nathan G. Allen, Jennifer S. Blumenthal-Barby & Laurence B. McCullough (2015). Placing and Evaluating Unproven Interventions Within a Clinical Ethical Taxonomy of Treatments for Ebola Virus Disease. American Journal of Bioethics 15 (4):50-53.
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  17.  5
    Laurence B. McCullough (2015). Medicine as a Profession: A Hypothetical Imperative in Clinical Ethics. Journal of Medicine and Philosophy 40 (1):1-7.
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  18.  4
    Tessy A. Thomas & Laurence B. McCullough (2015). A Philosophical Taxonomy of Ethically Significant Moral Distress: Figure 1. Journal of Medicine and Philosophy 40 (1):102-120.
    Moral distress is one of the core topics of clinical ethics. Although there is a large and growing empirical literature on the psychological aspects of moral distress, scholars, and empirical investigators of moral distress have recently called for greater conceptual clarity. To meet this recognized need, we provide a philosophical taxonomy of the categories of what we call ethically significant moral distress: the judgment that one is not able, to differing degrees, to act on one’s moral knowledge about what one (...)
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  19.  48
    Laurence B. McCullough (1984). Patients with Reduced Agency: Conceptual, Empirical, and Ethical Considerations. Journal of Medicine and Philosophy 9 (4):329-332.
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  20.  61
    Laurence B. McCullough (1995). Preventive Ethics, Professional Integrity, and Boundary Setting: The Clinical Management of Moral Uncertainty. Journal of Medicine and Philosophy 20 (1):1-11.
  21.  42
    Laurence B. McCullough (1994). Philosophy Matters to Medicine. Journal of Medicine and Philosophy 19 (1):1-5.
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  22.  3
    Laurence B. McCullough (forthcoming). Contributions of Ethical Theory to Pediatric Ethics Pediatricians and Parents as Co-Fiduciaries of Pediatric Patients. Pediatric Bioethics.
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  23.  33
    Judith C. Ahronheim, Jonathan Moreno, Connie Zuckerman & Laurence B. McCullough (1995). Ethics in Clinical Practice. HEC Forum 7 (6):377-378.
  24. John Gregory & Laurence B. Mccullough (1998). John Gregory's Writings on Medical Ethics and Philosophy of Medicine.
     
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  25.  80
    Laurence B. McCullough (1979). Rights, Health Care, and Public Policy. Journal of Medicine and Philosophy 4 (2):204-215.
  26. Laurence B. McCullough (2013). Professional Responsibility to and for Patients and the Ethics of Health Policy. American Journal of Bioethics 13 (8):16-18.
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  27.  12
    A. A. Eduard Verhagen, Pieter J. Sauer, Daniel Callahan, Frank A. Chervenak, Laurence B. McCullough, Birgit Arabin, Tim Smith & Georgia Goldfarb (2008). "Are Their Babies Different From Ours?": Dutch Culture and the Groningen Protocol. Hastings Center Report 38 (4):4-7.
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  28. Tom L. Beauchamp & Laurence B. Mccullough (1985). Medical Ethics: The Moral Responsibilities of Physicians. The Personalist Forum 1 (2):112-115.
     
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  29.  13
    Frank A. Chervenak & Laurence B. McCullough (2011). A Case Study in Junk Bioethics Run Amok. American Journal of Bioethics 11 (12):59-61.
    The American Journal of Bioethics, Volume 11, Issue 12, Page 59-61, December 2011.
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  30.  5
    Frank A. Chervenak & Laurence B. McCullough (1991). Justified Limits on Refusing Intervention. Hastings Center Report 21 (2):12-18.
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  31.  17
    Laurence B. McCullough (1999). Hume's Influence on John Gregory and the History of Medical Ethics. Journal of Medicine and Philosophy 24 (4):376 – 395.
    The concept of medicine as a profession in the English-language literature of medical ethics is of recent vintage, invented by the Scottish physician and medical ethicist, John Gregory (1724-1773). Gregory wrote the first secular, philosophical, clinical, and feminine medical ethics and bioethics in the English language and did so on the basis of Hume's principle of sympathy. This paper provides a brief account of Gregory's invention and the role that Humean sympathy plays in that invention, with reference to key texts (...)
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  32.  10
    Laurence B. McCullough (1983). Introduction. Theoretical Medicine and Bioethics 4 (3).
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  33.  11
    Laurence B. McCullough (2005). The Critical Turn in Clinical Ethics and its Continous Enhancement. Journal of Medicine and Philosophy 30 (1):1 – 8.
    Taking the critical turn is one of the main tools of the humanities and inculcates an intellectual discipline that prevents ossification of thinking about issues and of organizational policies in clinical ethics. The articles in this "Clinical Ethics" number of the Journal take the critical turn with respect to cherished ways of thinking in Western clinical ethics, life extension, the clinical determination of death, physicians' duty to treat even at personal risk, clinical ethics at the interface of research ethics, and (...)
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  34.  56
    Loretta M. Kopelman & Laurence B. McCullough (1999). Hume, Bioethics, and Philosophy of Medicine. Journal of Medicine and Philosophy 24 (4):315 – 321.
  35.  31
    Laurence B. McCullough (1981). Thought-Styles, Diagnosis, and Concepts of Disease: Commentary on Ludwik Fleck. Journal of Medicine and Philosophy 6 (3):257-262.
  36.  34
    Laurence B. McCullough (1996). Reification and Synergy in Clinical Ethics and its Adequacy to the Managed Practice of Medicine. Journal of Medicine and Philosophy 21 (1):1-6.
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  37.  8
    Patricia Agre, Frances A. Campbell, Barbara D. Goldman, Maria L. Boccia, Nancy Kass, Laurence B. McCullough, Jon F. Merz, Suzanne M. Miller, Jim Mintz & Bruce Rapkin (forthcoming). Improving Informed Consent: The Medium is Not the Message. IRB: Ethics & Human Research.
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  38.  29
    Laurence B. McCullough (2002). Philosophical Challenges in Teaching Bioethics: The Importance of Professional Medical Ethics and its History for Bioethics. Journal of Medicine and Philosophy 27 (4):395 – 402.
    The papers in this number of the Journal originated in a session sponsored by the American Philosophical Association's Committee on Philosophy and Medicine in 1999. The four papers and two commentaries identify and address philosophical challenges of how we should understand and teach bioethics in the liberal arts and health professions settings. In the course of introducing the six papers, this article explores themes these papers raise, especially the relationship among professional medical ethics, the "long history" of medical ethics, and (...)
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  39.  5
    Aanand D. Naik, Carmel B. Dyer, Mark E. Kunik & Laurence B. McCullough (2009). Response to Commentaries on “Patient Autonomy for the Management of Chronic Conditions: A Two-Component Re-Conceptualization”. American Journal of Bioethics 9 (2):W3 – W5.
  40.  3
    Laurence B. McCullough (2016). Physicians’ Professionally Responsible Power: A Core Concept of Clinical Ethics. Journal of Medicine and Philosophy 41 (1):1-9.
    The gathering of power unto themselves by physicians, a process supported by evidence-based practice, clinical guidelines, licensure, organizational culture, and other social factors, makes the ethics of power—the legitimation of physicians’ power—a core concept of clinical ethics. In the absence of legitimation, the physician’s power over patients becomes problematic, even predatory. As has occurred in previous issues of the Journal, the papers in the 2016 clinical ethics issue bear on the professionally responsible deployment of power by physicians. This introduction explores (...)
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  41.  6
    Laurence B. McCullough (1998). Response to Brown. The Leibniz Review 8:95-99.
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  42.  3
    Laurence B. McCullough (2006). The Ethical Concept of Medicine as a Profession: Its Origins in Modern Medical Ethics and Implications for Physicians. Advances in Bioethics 10:17-27.
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  43.  46
    Robert Baker & Laurence B. McCullough (2007). The Relationship Between Moral Philosophy and Medical Ethics Reconsidered. Kennedy Institute of Ethics Journal 17 (3):271-276.
    : Medical ethics often is treated as applied ethics, that is, the application of moral philosophy to ethical issues in medicine. In an earlier paper, we examined instances of moral philosophy's influence on medical ethics. We found the applied ethics model inadequate and sketched an alternative model. On this model, practitioners seeking to change morality "appropriate" concepts and theory fragments from moral philosophy to valorize and justify their innovations. Goldilocks-like, five commentators tasted our offerings. Some found them too cold, since (...)
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  44.  29
    Laurence B. McCullough (1981). Pluralism, Philosophies of Medicine and the Varieties of Medical Ethics: A Commentary on Thomasma and Pellegrino. Theoretical Medicine and Bioethics 2 (1):13-17.
    Some problems that arise in the account given by Thomasma and Pellegrino [6] of the foundations of medical ethics in a philosophy of medicine are addressed, in particular questions of a conceptual character about treating therelatum of medicine as health. Which concept of health is appropriate and which will bear the burden of the position thomasma and Pellegrino advance? It is argued that the proper relationship of medicine is one between a healer and developing embodied minds. As a consequence, the (...)
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  45.  12
    Laurence B. McCullough (1999). A Basic Concept in the Clinical Ethics of Managed Care: Physicians and Institutions as Economically Disciplined Moral Co-Fiduciaries of Populations of Patients. Journal of Medicine and Philosophy 24 (1):77 – 97.
    Managed care employs two business tools of managed practice that raise important ethical issues: paying physicians in ways that impose conflicts of interest on them; and regulating physicians' clinical judgment, decision making, and behavior. The literature on the clinical ethics of managed care has begun to develop rapidly in the past several years. Professional organizations of physicians have made important contributions to this literature. The statements on ethical issues in managed care of four such organizations are considered here, the American (...)
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  46.  7
    Amy L. McGuire & Laurence B. McCullough (2005). Respect as an Organizing Normative Category for Research Ethics. American Journal of Bioethics 5 (1):W1 – W2.
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  47.  11
    Laurence B. McCullough (1998). Preventive Ethics, Managed Practice, and the Hospital Ethics Committee as a Resource for Physician Executives. HEC Forum 10 (2):136-151.
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  48.  3
    Chris Feudtner, Jeremy Sugarman, Barbara A. Koenig, Peter A. Ubel, Richard F. Ittenbach, Laura Weiss Roberts & Laurence B. McCullough (2014). AJOB Empirical Bioethics: A Home for Empirical Bioethics Scholarship. Ajob Empirical Bioethics 5 (1):1-2.
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  49. Laurence B. Mccullough, James W. Jones & Baruch A. Brody (1998). Surgical Ethics. Monograph Collection (Matt - Pseudo).
     
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  50.  4
    Frank A. Chervenak & Laurence B. McCullough (1993). Clinical Management of Brain Death During Pregnancy. Journal of Clinical Ethics 4 (4):349.
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