Online research in philosophy

This paper explores structuralism as a way to model theories from scientific practice. As a case study I analyzed a theory about the dynamics of the basal ganglia, a part of the brain that is involved in Parkinson's disease. After introducing the case study I explore how to structurally represent qualitative assumptions about disease, intervention and dynamical systems in general. I further explicate the structure of the basal ganglia theory in detail, how it explains Parkinson's disease and how it implies (...) treatments. I close with a consideration of how a structuralist representation could be useful in practice to explore and develop theories with the aid of a computer. (shrink)

One method to determine the asymptotics of particular solutions of a difference equation is by solving an associated asymptotic functional equation. Here we study the behaviour of the solutions in an asymptotic neighbourhood of such individual solutions. We identify several types of attraction and repulsion, which range from almost orthogonality to almost parallelness. Necessary and sufficient conditions for these types of behaviour are given.

I define serendipity as the art of making an unsought finding. And I propose an overview of my collection of serendipities, the largest yet assembled, chiefly in science and technology, but also in art, by giving a list of ‘serendipity patterns’. Although my list of ‘patterns’ is just a list and not a classification, it serves to introduce a new and possibly stimulating perspective on the old subject of serendipity. Knowledge of these ‘serendipity patterns’ might help in expecting also the (...) unexpected and in finding also the unsought. * I acknowledge A. D. de Groot, R. C. M. Noordam, B. P. van Heusden, T. Pinkster, C. J. van den Berg, T. A. F. Kuipers, A. Wegener Sleeswijk and my referee for their suggestions and I dedicate this article to T. A. van Kooten. Cases and studies of serendipidy are welcome. À propos: a travelling serendipity exhibition is available, also for ‘new democracies’: ‘Freedom of opportunity as developed by democracy is the best human reaction to divergent phenomena. We may, in fact, define ‘freedom’ as ‘the opportunity to profit from the unexpected.’ (Langmuir [1956]). (shrink)

This article focuses on maternal-fetal surgery (MFS) and on the concept of clinical equipoise that is a widely accepted requirement for conducting randomized controlled trials (RCT). There are at least three reasons why equipoise is unsuitable for MFS. First, the concept is based on a misconception about the nature of clinical research and the status of research subjects. Second, given that it is not clear who the research subject/s in MFS is/are, if clinical equipoise is to be used as a (...) criterion to test the ethical appropriateness of RCT, its meaning should be unambiguous. Third, because of the multidisciplinary character of MFS, it is not clear who should be in equipoise. As a result, we lack an adequate criterion for the ethical review of MFS protocols. In our account, which is based on Chervenak and McCullough's seminal work in the field of obstetric ethics, equipoise is abandoned. and RCT involving MFS can be ethically initiated when a multidisciplinary ethics review board (ERB), having an evidence-based assessment of the risks involved, is convinced that the value of answering the research hypothesis, for the sake of the health interests of future pregnant women carrying fetuses with certain congenital birth defects, justifies the actual risks research participants might suffer within a set limit of low/manageable. (shrink)

O. Renn, P.-J. Schweizer, M. Dreyer, A. Klinke: Risiko. Über den gesellschaftlichen Umgang mit Unsicherheit Content Type Journal Article DOI 10.1007/s10202-009-0071-9 Authors Stephan Lingner, Europäische Akademie zur Erforschung von Folgen wissenschaftlich-technischer Entwicklungen Bad Neuenahr-Ahrweiler GmbH Wilhelmstr. 56 53474 Bad Neuenahr-Ahrweiler Germany Journal Poiesis & Praxis: International Journal of Technology Assessment and Ethics of Science Online ISSN 1615-6617 Print ISSN 1615-6609 Journal Volume Volume 6 Journal Issue Volume 6, Numbers 3-4.

Analysis shows that statements of ability are disguised conditionals. More exactly, the correct analysis of 'X could have done A' is 'If X h decided (chosen, willed ...) to do A, X would have done A'. Therefore having acted freely--having been able to act otherwise than one fact did--is compatible with determinism (with the causal determination of one's acts).

On a few occasions F.A. Hayek made reference to the famous Gödel theorems in mathematical logic in the context of expounding his cognitive and social theory. The exact meaning of the supposed relationship between Gödel's theorems and the essential proposition of Hayek's theory of mind remains subject to interpretation, however. The author of this article argues that the relationship between Hayek's thesis that the human brain can never fully explain itself and the essential insight provided by Gödel's theorems in mathematical (...) logic has the character of an analogy, or a metaphor. Furthermore the anti-mechanistic interpretation of Hayek's theory of mind is revealed as highly questionable. Implications for the Socialist Calculation Debate are highlighted. It is in particular concluded that Hayek's arguments for methodological dualism, when compared with those of Ludwig von Mises, actually amount to a strengthening of the case for methodological dualism. (shrink)