Online research in philosophy

I distinguish three evolutionary explanations of mental illness: first, breakdowns in evolved computational systems; second, evolved systems performing their evolutionary function in a novel environment; third, evolved personality structures. I concentrate on the second and third explanations, as these are distinctive of an evolutionary psychopathology, with progressively less credulity in the light of the empirical evidence. General morals are drawn for evolutionary psychiatry.

Most moral philosophers agree that if a moral agent is incapable of performing some act ф because of a physical incapacity, then they do not have a reason to ф. Most also claim that if an agent is incapable of ф-ing due to a psychological incapacity, brought about by, for example, an obsession or phobia, then this does not preclude them from having a reason to ф. This is because the ‘ought implies can’ principle is usually interpreted as a (...) claim about physical, rather than psychological, capacities. In this paper I argue for an opposing view: if we don’t have reasons to do things that we are physically incapable of doing, then neither do we have reasons to do things we are psychologically incapable of doing. I also argue that extending the ‘ought implies can’ principle to psychological capacities makes the principle more attractive. (shrink)

The DSM-III, DSM-IV, DSM-IV-TR and ICD-10 have judiciously minimized discussion of etiologies to distance clinical psychiatry from Freudian psychoanalysis. With this goal mostly achieved, discussion of etiological factors should be reintroduced into the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V). A research agenda for the DSM-V advocated the "development of a pathophysiologically based classification system". The author critically reviews the neuroevolutionary literature on stress-induced and fear circuitry disorders and related amygdala-driven, species-atypical fear behaviors of clinical severity in (...) adult humans. Over 30 empirically testable/falsifiable predictions are presented. It is noted that in DSM-IV-TR and ICD-10, the classification of stress and fear circuitry disorders is neither mode-of-acquisition-based nor brain-evolution-based. For example, snake phobia (innate) and dog phobia (overconsolidational) are clustered together. Similarly, research on blood-injection-injury-type-specific phobia clusters two fears different in their innateness: 1) an arguably ontogenetic memory-trace-overconsolidation-based fear (hospital phobia) and 2) a hardwired (innate) fear of the sight of one's blood or a sharp object penetrating one's skin. Genetic architecture-charting of fear-circuitry-related traits has been challenging. Various, non-phenotype-based architectures can serve as targets for research. In this article, the author will propose one such alternative genetic architecture. This article was inspired by the following: A) Nesse's "Smoke-Detector Principle", B) the increasing suspicion that the "smooth" rather than "lumpy" distribution of complex psychiatric phenotypes (including fear-circuitry disorders) may in some cases be accounted for by oligogenic (and not necessarily polygenic) transmission, and C) insights from the initial sequence of the chimpanzee genome and comparison with the human genome by the Chimpanzee Sequencing and Analysis Consortium published in late 2005. Neuroevolutionary insights relevant to fear circuitry symptoms that primarily emerge overconsolidationally (especially Combat related Posttraumatic Stress Disorder) are presented. Also introduced is a human-evolution-based principle for clustering innate fear traits. The "Neuroevolutionary Time-depth Principle" of innate fears proposed in this article may be useful in the development of a neuroevolution-based taxonomic re-clustering of stress-triggered and fear-circuitry disorders in DSM-V. Four broad clusters of evolved fear circuits are proposed based on their time-depths: 1) Mesozoic (mammalian-wide) circuits hardwired by wild-type alleles driven to fixation by Mesozoic selective sweeps; 2) Cenozoic (simian-wide) circuits relevant to many specific phobias; 3) mid Paleolithic and upper Paleolithic (Homo sapiens-specific) circuits (arguably resulting mostly from mate-choice-driven stabilizing selection); 4) Neolithic circuits (arguably mostly related to stabilizing selection driven by gene-culture co-evolution). More importantly, the author presents evolutionary perspectives on warzone-related PTSD, Combat-Stress Reaction, Combat-related Stress, Operational-Stress, and other deployment-stress-induced symptoms. The Neuroevolutionary Time-depth Principle presented in this article may help explain the dissimilar stress-resilience levels following different types of acute threat to survival of oneself or one's progency (aka DSM-III and DSM-V PTSD Criterion-A events). PTSD rates following exposure to lethal inter-group violence (combat, warzone exposure or intentionally caused disasters such as terrorism) are usually 5-10 times higher than rates following large-scale natural disasters such as forest fires, floods, hurricanes, volcanic eruptions, and earthquakes. The author predicts that both intentionally-caused large-scale bioevent-disasters, as well as natural bioevents such as SARS and avian flu pandemics will be an exception and are likely to be followed by PTSD rates approaching those that follow warzone exposure. During bioevents, Amygdala-driven and locus-coeruleus-driven epidemic pseudosomatic symptoms may be an order of magnitude more common than infection-caused cytokine-driven symptoms. Implications for the red cross and FEMA are discussed. It is also argued that hospital phobia as well as dog phobia, bird phobia and bat phobia require re-taxonomization in DSM-V in a new "overconsolidational disorders" category anchored around PTSD. The overconsolidational spectrum category may be conceptualized as straddling the fear circuitry spectrum disorders and the affective spectrum disorders categories, and may be a category for which Pitman's secondary prevention propranolol regimen may be specifically indicated as a "morning after pill" intervention. Predictions are presented regarding obsessive-compulsive disorder (OCD) (e.g., female-pattern hoarding vs. male-pattern hoarding) and "culture-bound" acute anxiety symptoms (taijin-kyofusho, koro, shuk yang, shook yong, suo yang, rok-joo, jinjinia-bemar, karoshi, gwarosa, Voodoo death). Also discussed are insights relevant to pseudoneurological symptoms and to the forthcoming Dissociative-Conversive disorders category in DSM-V, including what the author terms fright-triggered acute pseudo-localized symptoms (i.e., pseudoparalysis, pseudocerebellar imbalance, psychogenic blindness, pseudoseizures, and epidemic sociogenic illness). Speculations based on studies of the human abnormal-spindle-like, microcephaly-associated (ASPM) gene, the microcephaly primary autosomal recessive (MCPH) gene, and the forkhead box p2 (FOXP2) gene are made and incorporated into what is termed "The pre-FOXP2 Hypothesis of Blood-Injection-Injury Phobia." Finally, the author argues for a non-reductionistic fusion of "distal (evolutionary) neurobiology" with clinical "proximal neurobiology," utilizing neurological heuristics. It is noted that the value of re-clustering fear traits based on behavioral ethology, human-phylogenomics-derived endophenotypes and on ontogenomics (gene-environment interactions) can be confirmed or disconfirmed using epidemiological or twin studies and psychiatric genomics. (shrink)

In the epilogue to The Mind and the Brain , we read: "Finally, after a generation or more in which biological materialism has had neuroscience -- indeed, all the life sciences -- in a chokehold, we may at last be breaking free.... Biological materialism did and does have real-world consequences. We feel its reach every time a pharmaceutical company tells us that, to cure shyness (or "social phobia"), we need only reach for a little pill.... Biological materialism is nothing (...) if not appealing. We need not address the emotional or spiritual causes of our sadness to have the cloud of depression lift; we need not question the way we teach our children before we can rid them of attention deficit disorder.". (shrink)

Previous research (Kielbasa, Pomerantz, Krohn, & Sullivan, 2004; Pomerantz & Segrist, 2006) indicates that when psychologists consider a client with symptoms of depression or anxiety, payment method significantly influences diagnostic decisions. This study extends the scope of the previous research to consider clients with symptoms of social phobia and attention deficit hyperactivity disorder (ADHD). Psychologists in independent practice responded to vignettes of clients whose descriptions deliberately included subclinical impairment. Half of the participants were told that the clients would pay (...) via managed care; the other half were told that the clients would pay out-of-pocket. Confirming previous studies, payment method had a highly significant impact on diagnosis such that compared to out-of-pocket clients, managed care clients were much more likely to be assigned Diagnostic and Statistical Manual of Mental Disorders (4th ed. [DSM-IV]; American Psychiatric Association, 1994) diagnoses. Ethical implications relate to informed consent, accuracy and truthfulness in diagnosis, and psychologists' integrity. (shrink)

Rationality and Compulsion presents a unique examination of mental illness - derived from philosophical action theory. Delusion is common to many mental disorders, resulting in actions that, though perhaps rational to the individual, might seem entirely inappropriate or harmful to others. So what is it that causes these actions, and why do they continue? The theory expounded in this book shows how the key to this problem might be compulsion. -/- This book presents a new analysis of the notion of (...) compulsion - developed from action theory. The books starts with an introduction to action theory (for the benefit of non-philosophers). It then shows how insights from action theory can help us better understand mental illness, before developing an analysis of compulsion that emphasizes the element of unavoidability. The book argues that what is fundamentally disturbing to the person suffering from delusion is not so much the fact that the disorder tends to lead to irrational actions but rather the fact that he or she is unable to avoid performing these actions. The individual is or feels compelled to act in the way he or she does. The book contains some concrete illustrations of this idea as applied to several psychiatric diagnoses, such as paranoia, phobia, and psychopathy. -/- Rationality and Compulsion is a highly original new work from a leading figure in the philosophy and psychiatry movement. It will advance our understanding of mental illness, and be valuable for psychiatrists, psychologists, as well as philosophers. (shrink)

The politics of nativism directed at Catholic immigrants in 19th-century America offer a fruitful comparative perspective through which to analyze the discourse and the politics of Islam in contemporary Europe. Anti-Catholic nativism constituted a peculiar North American version of the larger and more generalized phenomenon of anti-immigrant populist xenophobic politics which one finds in many countries and in different historical contexts. What is usually designated as Islamo-phobia in contemporary Europe, however, manifests striking resemblances with the original phenomenon of American (...) nativism that emerged in the middle of the 19th century in the United States. In both cases one finds the fusion of anti-immigrant xenophobic attitudes, perennial inter-religious prejudices, and an ideological construct setting a particular religious-civilizational complex in essential opposition to Western modernity. Although an anti-Muslim discourse emerged also in the United States after 11 September, it had primarily a geo-political dimension connected with the ‘war on terror’ and with American global imperial policies. But it lacked the domestic anti-immigrant populist as well as the modern secularist anti-Muslim dimensions. This explains why xenophobic anti-Muslim nativism has been much weaker in the United States than in Europe. (shrink)

Recent years have witnessed a ground swell of interest in the application of evolutionary theory to issues in psychopathology (Nesse & Williams 1995, Stevens & Price 1996, McGuire & Troisi 1998). Much of this work has been aimed at finding adaptationist explanations for a variety of mental disorders ranging from phobias to depression to schizophrenia. There has, however, been relatively little discussion of the implications that the theories proposed by evolutionary psychologists might have for the classification of mental disorders. This (...) is the theme we propose to explore. We'll begin, in Section 2, by providing a brief overview of the account of the mind advanced by evolutionary psychologists. In Section 3 we'll explain why issues of taxonomy are important and why the dominant approach to the classification of mental disorders is radically and alarmingly unsatisfactory. We will also indicate why we think an alternative approach, based on theories in evolutionary psychology, is particularly promising. In Section 4 we'll try to illustrate some of the virtues of the evolutionary psychological approach to classification. The discussion in Section 4 will highlight a quite fundamental distinction between those disorders that arise from the malfunction of a component of the mind and those that can be traced to the fact that our minds must now function in environments that are very different from the environments in which they evolved. This mis-match between the current and ancestral environments can, we maintain, give rise to serious mental disorders despite the fact that, in one important sense, there is nothing at all wrong with the people suffering the disorder. Their minds are functioning exactly as Mother Nature intended them to. In Section 5, we'll give a brief overview of some of the ways in which the sorts of malfunctions catalogued in Section 4 might arise, and sketch two rather different strategies for incorporating this etiologically. (shrink)

I am interested in fear of non-existence, which is often discussed in terms of fear one’s own death, or as it is sometimes called, fear of death as such. This form of fear has been denied by some philosophers. Cognitive theories of the emotions have particular trouble in dealing with it, granting it a status that is simultaneously paradigmatic yet anomalous with respect to fear in general. My paper documents these matters, and considers a number of responses. I provide examples (...) from philosophy and literature of fear of non-existence, and distinguish it from other death-related fears. I then look at the success that cognitive theories of the emotions have had in dealing with other “problematic” fears, such as phobias, and examine how the solutions here fail to apply to fear of non-existence. The problem lies with the perceptual-centred model of fear that is typically called upon. Against this I recommend a retreat to a belief-centred model for fear of non-existence. I argue that there are other fears that are better explained by a belief-centred rather a perceptual-based approach. This reinforces the plausibility of the belief-centred model, and goes some way to alleviating the anomalous and problematic status of the fear of non-existence. (shrink)

The “hypervigilance, escape, struggle, tonic immobility” evolutionarily hardwired acute peritraumatic response sequence is important for clinicians to understand. Our commentary supplements the useful article on human tonic immobility (TI) by Marx, Forsyth, Gallup, Fusé and Lexington (2008). A hallmark sign of TI is peritraumatic tachycardia, which others have documented as a major risk factor for subsequent posttraumatic stress disorder (PTSD). TI is evolutionarily highly conserved (uniform across species) and underscores the need for DSM-V planners to consider the inclusion of evolution (...) theory in the reconceptualization of anxiety and PTSD. We discuss the relevance of evolution theory to the DSM-V reconceptualization of acute dissociativeconversion symptoms and of epidemic sociogenic disorder(epidemic “hysteria”). Both are especially in need of attention in light of the increasing threat of terrorism against civilians. We provide other pertinent examples. Finally, evolution theory is not ideology driven (and makes testable predictions regarding etiology in “both directions”). For instance, it predicted the unexpected finding that some disorders conceptualized in DSM-IV-TR as innate phobias are conditioned responses and thus better conceptualized as mild forms of PTSD. Evolution theory may offer a conceptual framework in DSM-V both for treatment and for research on psychopathology. (shrink)

Place is sometimes understood as reinforcing personal and cultural identity in the face of dissipating versions of modernism or postmodernism. However, that identity can also come with a variety of cultural neuroses and manias that are inscribed on place. I consider the ways in which terrorism has become a feature of place, and how we can expect to see the terror of the place in the future. First, we can expect a relative diminishment in 'place-making imagination', the ability to see (...) places as rich, ambiguous, and multi-purposed. Second, we can expect the terror of the place to exhibit itself as an inability to come to terms with the other. Third, we can expect the continuation and development of a triumphalist narrative of place, including a sense of entitlement. Fourth, we can anticipate the death or the fear of the agora, the true 'agoraphobia', as the public space of discourse is closed down, and the private space of patriarchally enforced agreement gains ascendancy. Fifth, we can expect people to regard specific places as having fixed and permanent meanings, and to try to constrain those meanings in such a way as to guarantee that permanence. Sixth, we can expect topophobia, not only the fear of place but also stage fright, as the expression of self on the world stage becomes more and more limited and narrowly focussed. And seventh, we can expect a re-assertion of memory of place, perhaps with a shifted baseline, as the places of terror become exhausted. We can furthermore expect all of these phobias and manias to be rationalized as virtue in a society that cannot deal with the terror of the place. (shrink)

Behavioral momentum theory has evolved within the realm of operant conditioning. The thought-provoking momentum metaphor equates the strength of an operant response with its resistance to change and preference (i.e., choice) for that response over other available responses. Whereas baseline response rate (velocity in the metaphor) is assumed to be largely influenced by the response-reinforcer contingency, resistance to change and preference are assumed to reflect an intervening variable called behavioral mass, which is determined primarily by the stimulus-reinforcer relationship. This invites (...) the question of how well the momentum metaphor applies to the stimulus-reinforcer relationships of traditional Pavlovian paradigms. Presumably, a correspondence exists between behavioral mass and the notion of associative strength in the associative learning literature. Although response rate has little meaning in the trialwise structure of classical (i.e., Pavlovian) conditioning, response probability or magnitude might be regarded metaphorically as velocity. Momentum theory suggests that resistance to change (e.g., extinction) is a better indicator of associative strength than is response probability or magnitude. Therefore, variables that strengthen Pavlovian learning should influence resistance to extinction of conditioned responding in a similar manner. Moreover, it is important to assess momentum theory outside of strictly operant paradigms, particularly because in clinical settings many common disorders (e.g., phobias) and their therapies (e.g., cue exposure) are thought to be classically conditioned. (shrink)

We develop the concept of a volitional disability as an aid in understanding those patients who behave in ways that are harmful to themselves in spite of their desire to do otherwise. Using this concept enables us to describe their behavior as intentional but ‘unvoluntary’. We demonstrate the clinical reality of such behavior by giving clinical examples of the behavior of those with phobic, compulsive, and addictive disorders. We then attempt to show how some (...) kinds of self-harming behavior of noncompliant patients are similar to phobic and compulsive behavior. We propose use of the concept of volitional disability to make it easier for physicians to work with these noncompliant patients and thus to improve their ability to provide better care for them. Keywords: alcoholism, volitional disability, physician attitudes, addictive, disorders, compulsions, phobias, noncompliance CiteULike Connotea Del.icio.us What's this?. (shrink)

Common sense would suggest that we are in complete control of the actions we perform - that all our actions are the result of considered and conscious preparation. Yet, there are countless examples of this control breaking down, for example, in the case of phobias and compulsive actions. We can all recall those times when, in the 'heat of the moment', our actions have been very different to those that would have resulted from calm and considered reflection. In extreme moments (...) of 'absent-mindedness' our actions can even have castastrophic consequences, resulting in harm to ourselves or others. So why does this happen - why do apparently rational and intelligent beings make, what appear to be, such fundamental errors in their thinking. -/- This book explores the idea that humans have two distinct minds within their brains: one intuitive and the other reflective. The intuitive mind is old, evolved early, and shares many of its features with animal cognition. It is the source of emotion and intuitions, and reflects both the habits acquired in our lifetime and the adaptive behaviours evolved by ancient ancestors. The reflective mind, by contrast, is recently evolved and distinctively human: it enables us to think in abstract and hypothetical ways about the world around us and to calculate the future consequences of our actions. The evolution of the new, reflective mind is linked with the development of language and the very large forebrains that distinguish humans from other species; it has also given us our unique human form of intelligence. On occasions though, our two minds can come into in conflict, and when this happens, the old mind often wins. These conflicts are often rationalised so that we, conscious persons, are unaware that the intuitive mind is in control. -/- Written by a leading cognitive scientist, this book demonstrates how much of our behaviour is controlled by automatic and intuitive mental processes, which shape, as well as compete, with our conscious thinking and decision making. Accessibly written, and assuming no prior knowledge of the field, the book will be fascinating reading for all those interested in human behaviour, including students and researchers in psychology, neuroscience, and philosophy. (shrink)