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    M. T. Alkire, R. J. Haier & J. H. Fallon (2000). Toward a Unified Theory of Narcosis: Brain Imaging Evidence for a Thalamocortical Switch as the Neurophysiologic Basis of Anesthetic-Induced Unconsciousness. Consciousness and Cognition 9 (3):370-386.
    A unifying theory of general anesthetic-induced unconsciousness must explain the common mechanism through which various anesthetic agents produce unconsciousness. Functional-brain-imaging data obtained from 11 volunteers during general anesthesia showed specific suppression of regional thalamic and midbrain reticular formation activity across two different commonly used volatile agents. These findings are discussed in relation to findings from sleep neurophysiology and the implications of this work for consciousness research. It is hypothesized that the essential common neurophysiologic mechanism underlying anesthetic-induced unconsciousness is, as with (...)
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  2. M. T. Alkire, R. J. Haier & H. F. James (1998). Toward the Neurobiology of Consciousness: Using Brain Imaging and Anesthesia to Investigate the Anatomy of Consciousness. In Stuart R. Hameroff, Alfred W. Kaszniak & A. C. Scott (eds.), Toward a Science of Consciousness II. MIT Press
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    M. T. Alkire, R. J. Haier, J. H. Fallon & S. J. Barker (1996). PET Imaging of Conscious and Unconscious Verbal Memory. Journal of Consciousness Studies 3 (5-6):448-62.
    One method for investigating the neurobiology of consciousness is to experimentally manipulate consciousness as a variable and then visualize the resultant functional brain changes with advanced imaging techniques. To begin investigation into this area, healthy volunteers underwent positron emission tomography scanning while listening to randomized word lists in both conscious and unconscious conditions. Following anaesthesia, subjects had no explicit memories. Nonetheless, subjects demonstrated implicit memory on a forced-choice test . These subsequent memory scores were correlated with regional brain metabolism measured (...)
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