The world is complex, but acknowledging its complexity requires an appreciation for the many roles context plays in shaping natural phenomena. In _Unsimple Truths, _Sandra Mitchell argues that the long-standing scientific and philosophical deference to reductive explanations founded on simple universal laws, linear causal models, and predict-and-act strategies fails to accommodate the kinds of knowledge that many contemporary sciences are providing about the world. She advocates, instead, for a new understanding that represents the rich, variegated, interdependent fabric of many levels (...) and kinds of explanation that are integrated with one another to ground effective prediction and action. Mitchell draws from diverse fields including psychiatry, social insect biology, and studies of climate change to defend “integrative pluralism”—a theory of scientific practices that makes sense of how many natural and social sciences represent the multi-level, multi-component, dynamic structures they study. She explains how we must, in light of the now-acknowledged complexity and contingency of biological and social systems, revise how we conceptualize the world, how we investigate the world, and how we act in the world. Ultimately _Unsimple Truths _argues that the very idea of what should count as legitimate science itself should change. (shrink)

This fine collection of essays by a leading philosopher of science presents a defence of integrative pluralism as the best description for the complexity of scientific inquiry today. The tendency of some scientists to unify science by reducing all theories to a few fundamental laws of the most basic particles that populate our universe is ill-suited to the biological sciences, which study multi-component, multi-level, evolved complex systems. This integrative pluralism is the most efficient way to understand the different and complex (...) processes - historical and interactive - that generate biological phenomena. This book will be of interest to students and professionals in the philosophy of science. (shrink)

Biological knowledge does not fit the image of science that philosophers have developed. Many argue that biology has no laws. Here I criticize standard normative accounts of law and defend an alternative, pragmatic approach. I argue that a multidimensional conceptual framework should replace the standard dichotomous law/ accident distinction in order to display important differences in the kinds of causal structure found in nature and the corresponding scientific representations of those structures. To this end I explore the dimensions of stability, (...) strength, and degree of abstraction that characterize the variety of scientific knowledge claims found in biology and other sciences. (shrink)

Beatty, Brandon, and Sober agree that biological generalizations, when contingent, do not qualify as laws. Their conclusion follows from a normative definition of law inherited from the Logical Empiricists. I suggest two additional approaches: paradigmatic and pragmatic. Only the pragmatic represents varying kinds and degrees of contingency and exposes the multiple relationships found among scientific generalizations. It emphasizes the function of laws in grounding expectation and promotes the evaluation of generalizations along continua of ontological and representational parameters. Stability of conditions (...) and strength of determination in nature govern projectibility. Accuracy, ontological level, simplicity, and manageability provide additional measures of usefulness. (shrink)

The `fact' of pluralism in science is nosurprise. Yet, if science is representing andexplaining the structure of the oneworld, why is there such a diversity ofrepresentations and explanations in somedomains? In this paper I consider severalphilosophical accounts of scientific pluralismthat explain the persistence of bothcompetitive and compatible alternatives. PaulSherman's `Levels of Analysis' account suggeststhat in biology competition betweenexplanations can be partitioned by the type ofquestion being investigated. I argue that thisaccount does not locate competition andcompatibility correctly. I then defend anintegrative (...) model for understanding pluralism. This view is based on taking seriously both thecomplexity and contingency of biologicalorganization and the idealized character ofbiological models. On this view, explanationbecomes, among other things, the location forthe integration of diverse models. I explicatemy argument by an analysis of explanations ofdivision of labor in social insects. (shrink)

The controversy regarding the unit of selection is fundamentally a dispute about what is the correct causal structure of the process of evolution by natural selection and its ontological commitments. By characterizing the process as consisting of two essential steps--interaction and transmission--a singular answer to the unit question becomes ambiguous. With such an account on hand, two recent defenses of competing units of selection are considered. Richard Dawkins maintains that the gene is the appropriate unit of selection and Robert Brandon, (...) in response, argues that the individual organism is better suited to the role. This paper argues that by making explicit the underlying questions that each of these views addresses, the apparent conflict can be resolved. Furthermore, such a resolution allows for a more complete and realistic understanding of the process of evolution by natural selection. (shrink)

This volume offers a collection of in-depth explorations of pragmatism as a framework for discussions in philosophy of science and metaphysics. Each chapter involves explicit reflection on what it means to be pragmatist, and how to use pragmatism as a guiding framework in addressing topics such as realism, unification, fundamentality, truth, laws, reduction, and more. -/- .

Multilevel research strategies characterize contemporary molecular inquiry into biological systems. We outline conceptual, methodological, and explanatory dimensions of these multilevel strategies in microbial ecology, systems biology, protein research, and developmental biology. This review of emerging lines of inquiry in these fields suggests that multilevel research in molecular life sciences has significant implications for philosophical understandings of explanation, modeling, and representation.

ABSTRACT It has long been held that the structure of a protein is determined solely by the interactions of the atoms in the sequence of amino acids of which it is composed, and thus the stable, biologically functional conformation should be predictable by ab initio or de novo methods. However, except for small proteins, ab initio predictions have not been successful. We explain why this is the case and argue that the relationship among the different methods, models, and representations of (...) protein structure is one of integrative pluralism. Our defence appeals to specific features of the complexity of the functional protein structure and to the partial character of representation in general. We present examples of integrative strategies in protein science. _1._ Introduction _2._ Partiality of Representation _3._ Protein Functional Complexity _4._ Modelling Protein Structure _4.1_ Integrating ab initio and experimental models _4.2_ Integrating multiple experimental models _5._ Conclusion. (shrink)

It has been claimed that ceteris paribus laws, rather than strict laws are the proper aim of the special sciences. This is so because the causal regularities found in these domains are exception-ridden, being contingent on the presence of the appropriate conditions and the absence of interfering factors. I argue that the ceteris paribus strategy obscures rather than illuminates the important similarities and differences between representations of causal regularities in the exact and inexact sciences. In particular, a detailed account of (...) the types and degrees of contingency found in the domain of biology permits a more adequate understanding of the relations among the sciences. (shrink)

In this article I consider the challenges for exporting causal knowledge raised by complex biological systems. In particular, James Woodward’s interventionist approach to causality identified three types of stability in causal explanation: invariance, modularity, and insensitivity. I consider an example of robust degeneracy in genetic regulatory networks and knockout experimental practice to pose methodological and conceptual questions for our understanding of causal explanation in biology. †To contact the author, please write to: Department of History and Philosophy of Science, University of (...) Pittsburgh, 1017 Cathedral of Learning, Pittsburgh, PA 15260; e‐mail: [email protected]. (shrink)

Art theory has consistently emphasised the importance of situational, cultural, institutional and historical factors in viewers’ experience of fine art. However, the link between this heavily context-dependent interpretation and the workings of the mind is often left unexamined. Drawing on relevance theory—a prominent, cogent and productive body of work in cognitive pragmatics—we here argue that fine art achieves its effects by prompting the use of cognitive processes that are more commonly employed in the interpretation of words and other stimuli presented (...) in a communicative context. We describe in particular how institutional factors effectively co-opt these processes for new ends, allowing viewers to achieve cognitive effects that they otherwise would not, and so provide cognitivist backing for an Institutional Theory of Art, such as that put forward by Arthur Danto. More generally, we situate and describe the Western fine art tradition as a phenomenon that is a consequence of both the cognitive processes involved in communication, and of cultural norms, practices and institutions. (shrink)

In this paper I discuss recent debates concerning etiological theories of functions. I defend an etiological theory against two criticisms, namely the ability to account for malfunction, and the problem of structural doubles. I then consider the arguments provided by Bigelow and Pargetter (1987) for a more forward looking account of functions as propensities or dispositions. I argue that their approach fails to address the explanatory problematic for which etiological theories were developed.

It has long been held that the structure of a protein is determined solely by the interactions of the atoms in the sequence of amino acids of which it is composed, and thus the stable, biologically functional conformation should be predictable by ab initio or de novo methods. However, except for small proteins, ab initio predictions have not been successful. We explain why this is the case and argue that the relationship among the different methods, models, and representations of protein (...) structure is one of integrative pluralism. Our defence appeals to specific features of the complexity of the functional protein structure and to the partial character of representation in general. We present examples of integrative strategies in protein science. 1. Introduction2. Partiality of Representation3. Protein Functional Complexity4. Modelling Protein Structure4.1 Integrating ab initio and experimental models4.2 Integrating multiple experimental models5. Conclusion. (shrink)

I argue that diversity and pluralism are valuable not just for science but for philosophy of science. Given the partiality and perspectivism of representation, pluralism preserving integration can...

An amended bootstrapping can avoid Christensen's counterexamples. Earman and Edidin argue that Christensen's examples to bootstrapping rely on his failure to analyze background knowledge. I add an additional condition to bootstrapping that is motivated by Glymour's remarks on variety of evidence. I argue that it avoids the problems that the examples raise. I defend the modification against the charge that it is holistic, and that it collapses into Bayesianism.

Division of labor and its associated phenomena have been viewed as prime examples of group-level adaptations. However, the adaptations are the result of the process of evolution by natural selection and thus require that groups of insects once existed and competed for reproduction, some of which had a heritable division of labor while others did not. We present models, based on those of Kauffman (1984) that demonstrate how division of labor may occur spontaneously among groups of mutually tolerant individuals. We (...) propose that division of labor itself is not a product of natural selection but instead is a "typical" outcome of self organization. (shrink)

In this essay, I revisit and extend my arguments for a view of science that is pluralistic, perspectival and pragmatist. I attempt to resolve mismatches between metaphysical assumptions, epistemological desiderata, and scientific practice. I consider long-held views about unity of science and reductionism, emergent properties and physicalism, exceptionless necessity in explanatory laws, and in the justification for realism. My solutions appeal to the partiality of representation, the perspectivism of theories and data, and the interactive co-construction of warranted claims for realism.

Van Fraassen's constructive empiricism is presently the most influential and well-developed alternative to scientific realism. In this paper I argue that a reasonable condition on the distinction between belief and agnosticism prevents van Fraassen from claiming that we can be agnostic about what a theory says about unobservable entities while simultaneously accepting that theory. The upshot is that we must find some other way to do justice both to the argument for constructive empiricism and to van Fraassen's cogent criticisms of (...) scientific realism. I suggest that a highly attractive alternative is founded upon semantic anti-realism, and that empiricists should develop this alternative. (shrink)

This book examines the theory and practice of argument in primary, secondary and tertiary education. Several of its chapters offer theoretical discussion of the forms and functions of argument within social, philosophical, historical and rhetorical contexts.

In this paper I argue that two domains of uncertainty should inform our strategies for making social policy on new genetic technologies. The first is biological complexity, which includes both unknown consequences on known variables and unknown unknowns. The second is value pluralism, which includes both moral conflict and moral pluralism. This framework is used to investigate policy on genetically modified food and suggests that adaptive management is required to track changes in biological knowledge of these interventions and that less (...) simplistic, polemic representations of scientific knowledge are required to permit democratic decision making. (shrink)

This is a collection of papers presented at the Symposium "Are There are Laws of Biology?", in the 1996 Biennial Meetings of the Philosophy of Science Association. It includes four separate papers: "Why Do Biologists Argue Like They Do?" by John Beatty, "Does Biology Have Laws? The Experimental Evidence" by Robert Brandon, "Two Outbreaks of Lawlessness in Recent Philosophy of Biology" by Elliott Sober, and "Pragmatic Laws" by Sandra D. Mitchell.

Philosophical accounts of emergence have been explicated in terms of logical relationships between statements (derivation) or static properties (function and realization). Jaegwon Kim is a modern proponent. A property is emergent if it is not explainable by (or reducible to) the properties of lower level components. This approach, I will argue, is unable to make sense of the kinds of emergence that are widespread in scientific explanations of complex systems. The standard philosophical notion of emergence posits the wrong dichotomies, confuses (...) compositional physicalism with explanatory physicalism, and is unable to represent the type of dynamic processes (self-organizing feedback) that both generate emergent properties and express downward causation. (shrink)

Titles and abstracts for the Pitt-London Workshop in the Philosophy of Biology and Neuroscience: September 2001.

Understanding what makes governance 'good' or 'bad' has been impeded by construct ambiguity. Contemporary governance research has struggled to define 'governance' and related constructs such as 'ownership', 'agency', and 'management' in a way that clearly separates and distinguishes them. Often, the line between governance and management is so blurred that it is impossible to say what is good or bad 'governance' versus 'management'. Here we provide a systematic classification of key governance concepts in terms of their distinct economic functions. 'Governance', (...) for instance, is the economic function of behavioural constraint. This allows us to state what 'good' governance is and how it might be assessed. We conclude that goodness of governance is idiosyncratic to each organisation, or even to each owner. Thus, while objective measures of good governance are possible, broadly utilised criteria for measuring governance are unlikely to capture whether governance is actually good or bad. (shrink)

Within the theoretical framework of the moral intensity model of ethical decision making (Jones, 1991), two studies ascertained the contention that ethicality judgements are contingent upon the perceived intensity of the moral issue. In addition, Study 1 extended the validity of the moral intensity notion to whistle-blowing behaviour; Study 2 addressed the effect of the individual difference variable, need-for-cognition, on differential utilization of intensity dimensions in the ethical decision process. A scenario approach was used in both studies. Results have provided (...) convergent support for the issue-contingency nature of ethical decisions. Study 1 also showed that felt empathy for potential victims predicted the likelihood of whistle-blowing behaviour, and that the perceived overall ethicality of a wrongdoing predicted felt empathy when potential victims are psychologically and physically close. Results of Study 2 further suggested a greater utilization of issue-relevant information by high need-for-cognition individuals in ethical decision making. (shrink)

When Augustus inherited the kingdom of Amyntas in or about 25 B.C. and created the Roman province of Galatia, he also inherited a substantial military problem. Despite Amynatas' efforts in a decade of warfare the tribes of the Isaurian and Pisidian Taurus, above all the Homonadenses, were still not finally conquered and posed a serious threat both to lacal security and to the routes of communication across southern Asia Minor.

This review serves the function of assessing Dawkins "The God Delusion". The thesis of “The God Delusion” is that there is no scientific evidence for a god, or other supernatural entity. Dawkins makes his case through a twofold approach where he discusses the horrors of theology and shows how evolution (science) works independent of a creator. The author of this review will make the case the Dawkins was not successful in meeting the criteria, in order to meet the threshold of (...) his thesis. (shrink)

The social organization of insect colonies has fascinated biologists and natural historians for centuries. Aristotle wrote in History of Animals about a division of labor among workers within the hive that is based on age. He observed that the field bees foraging for nectar and pollen have less “hair” on their bodies than the hive bees that care for young larvae and tend the nest. He concluded that the more pubescent hive bees must be older. We now know that, in (...) fact, the field bees are older and have less hair because the hairs break off as the bees age. The phenomenon of age related changes in behavior, age-polyethism, is now well documented for many social insects (Oster and Wilson 1978).Evidence of the ecological success of social insects is inescapable. Virtually everywhere you look you see them or the results of their activities. (shrink)

Van Fraassen stresses two distinct but interrelated themes in The Scientific Image: the semantic view of theories and the epistemic status of unobservables. The first of these could easily be accepted by a scientific realist, and indeed realists like Giere have already adapted it to their purposes. So the specifically empiricist thread in van Fraassen’s philosophy stems from the second.Van Fraassen breaks from tradition in founding his empiricism not on the ontological status of unobservable entities but on the epistemic attitude (...) we take to them. The main points of his position are these:1)The claims of scientific theories, including claims about unobservable entities, are to be taken literally. Theories are not reconstructed so as to remove claims of the existence of unobservable objects.2)Observation is a matter of direct observation by accepted participants in the human scientific community. (shrink)

Taking a pragmatist stance toward the practices and products of science shapes our answers to central philosophical questions. In argue that from within a perspective consisting of goals, actions and questions, what we say there is and what we say it does, is justified by the ongoing interactions among representative models, causal experience and experiment, and conceptual frameworks in reaching a fallible convergence to what is real. I offer a non-dichotomous alternative. I propose an alternative to fundamentalist approaches, arguing that (...) what we are justified in claiming as real phenomena are the affordances constructed from the integration of top-down and bottom-up strategies. (shrink)

One of today's most influential business consultants brings us practical lessons from one of the world's most profound works of wisdom for cultivating real power and transforming the workplace into a source of immense satisfaction and fulfillment.A former Fortune 500 top executive who is a leading business consultant combines forces with the bestselling translator of the Tao Te China to write the first book revealing how to use the wisdom of this ancient text to understand the most valued and elusive (...) prize in business: power. Power is the most coveted reward -- the power to run a project, a department, or an entire company. Yet there has been little written on the nature of this essential tool without which nothing is accomplished. What exactly is power, and where does it come from? Does power automatically come with authority? Does it come from your superiors, or do you create it for yourself? And why is it so difficult to hang on to?Real Power illustrates the paradox in winning at work: that power begins only when we learn to let go of the illusion of control in order to empower others. Real power recognizes that employees already have power in their skills, their commitment to the job, and their passion for the work. Real power comes from creating an environment in which that power can be expressed in order to produce the best results for everyone.The book's advice for cultivating real power ranges from learning why helping your competition (inside or outside the company) can be the biggest help to yourself, to understanding why conventional displays of power are the least effective ways to accomplish goals. Whether you're at the top of the corporate ladder, the middle, orthe bottom, this guide will help make your work fulfilling on every level From financial to personal. (shrink)

The insights described by Nevin & Grace may be summarized without reference to the Newtonian concepts they suggest. The metaphor to Newtonian mechanics seems dubious in three ways: (1) extensions seem to lead to paradoxes; (2) many well-known phenomena are ignored; (3) the Newtonian concepts seem difficult to reconcile with the larger framework of evolutionary theory.

Proceedings of the Pittsburgh Workshop in History and Philosophy of Biology, Center for Philosophy of Science, University of Pittsburgh, March 23-24 2001 Session 2: Female Orgasms and Evolutionary Theory.

In the published article the following information should have been included: Acknowledgment TSP was financially supported by Durham University’s Addison Wheeler bequest and by the European Research Council, under the European Union’s Seventh Framework Programme /ERC grant agreement no. 609819.