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  1. Sergio Sismondo, Publication Planning 101: A Report.
    Publication planning is the sub-industry to the pharmaceutical industry that does the organizational and practical work of shaping pharmaceutical companies' data and turning it into medical journal articles. Its main purpose is to create and communicate scientific information to support the marketing of products. This report is based mostly on information presented at the 2007 annual meeting of the International Society of Medical Planning Professionals, including a workshop entitled "Publication Planning 101/201", attended by one of us. We provide some analysis (...)
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  2. Sergio Sismondo, Social Studies of Science.
    Publication of pharmaceutical company-sponsored research in medical journals, and its presentation at conferences and meetings, is mostly governed by ‘publication plans’ that extract the maximum amount of scientific and commercial value out of data and analyses through carefully constructed and placed papers. Clinical research is typically performed by contract research organizations, analyzed by company statisticians, written up by independent medical writers, approved and edited by academic researchers who then serve as authors, and the whole process organized and shepherded through to (...)
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  3. Sergio Sismondo, Ghost Management: How Much of the Medical Literature is Shaped Behind the Scenes by the Pharmaceutical Industry?
    Anecdotes have shown that some articles on profitable drugs are constructed by and shepherded through publication by pharmaceutical companies and their agents, whose influence is largely invisible to readers. This is ghost-management, the substantial but unrecognized research, analysis, writing, editing and/or facilitation behind publication. Publicly available documents suggest that these practices extremely widespread affecting up to 40% of clinical trial reports in key periods but it has been unclear how representative these documents are. This article presents the results of an (...)
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  4. Sergio Sismondo, Pharmaceutical Company Funding and its Consequences: A Qualitative Systematic Review.
    This article systematically reviews published studies of the association of pharmaceutical industry funding and clinical trial results, as well a few closely related studies. It reviews two earlier results, and surveys the recent literature. Results are clear: Pharmaceutical company sponsorship is strongly associated with results that favor the sponsors' interests.
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  5. Sergio Sismondo, Pharmaceutical Maneuvers.
    In 2003, the pharmaceutical company Biovail received a spate of negative publicity around a program for its heart medication Cardizem LA. For a three-month period Biovail paid US doctors US$1000 (and their office managers US$150) for patient data when at least 11 of their patients renewed a prescription to Cardizem. Doctors who signed up for the trial but who did not keep 11 patients on the drug received US$250 for participation. According to Biovail, this was a research trial, meeting US (...)
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  6. Sergio Sismondo (2013). Key Opinion Leaders and the Corruption of Medical Knowledge: What the Sunshine Act Will and Won't Cast Light On. Journal of Law, Medicine and Ethics 41 (3):635-643.
    The pharmaceutical industry, in its marketing efforts, often turns to “key opinion leaders” or “KOLs” to disseminate scientific information. Drawing on the author's fieldwork, this article documents and examines the use of KOLs in pharmaceutical companies’ marketing efforts. Partly due to the use of KOLs, a small number of companies with well-defined and narrow interests have inordinate influence over how medical knowledge is produced, circulated, and consumed. The issue here, as in many other cases of institutional corruption, is that a (...)
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  7. Sergio sismondo, Linking Research and Marketing: A Pharmaceutical Innovation.
    In Vivian Quirke and Judy Slinn (eds.) Perspectives on 20th Century Pharmaceuticals (Peter Lang, forthcoming).
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  8. Sergio Sismondo (2009). Medical Research for Hire: The Political Economy of Pharmaceutical Clinical Trials – by Jill A. Fisher When Experiments Travel: Clinical Trials and the Global Search for Human Subjects – by Adriana Petryna. Bioethics 23 (9):522-524.
  9. Sergio Sismondo & Mathieu Doucet (2009). Publication Ethics and the Ghost Management of Medical Publication. Bioethics 24 (6):273-283.
    It is by now no secret that some scientific articles are ghost authored – that is, written by someone other than the person whose name appears at the top of the article. Ghost authorship, however, is only one sort of ghosting. In this article, we present evidence that pharmaceutical companies engage in the ghost management of the scientific literature, by controlling or shaping several crucial steps in the research, writing, and publication of scientific articles. Ghost management allows the pharmaceutical industry (...)
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  10. Sergio Sismondo (2004). An Introduction to Science and Technology Studies. Blackwell Pub..
    The prehistory of science and technology studies -- The Kuhnian revolution -- Questioning functionalism in the sociology of science -- Stratification and discrimination -- The strong programme and the sociology of knowledge -- The social construction of scientific and technical realities -- Feminist epistemologies of science -- Actor-network theory -- Two questions concerning technology -- Studying laboratories -- Controversies -- Standardization and objectivity -- Rhetoric and discourse -- The unnaturalness of science and technology -- The public understanding of science -- (...)
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  11. Sergio Sismondo (2004). Boundary Work and the Science Wars: James Robert Brown's Who Rules in Science? Episteme 1 (3):235-248.
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  12. Sergio Sismondo & Nicholas Chrisman (2001). Deflationary Metaphysics and the Natures of Maps. Proceedings of the Philosophy of Science Association 2001 (3):S38-.
    "Scientific theories are maps of the natural world." This metaphor is often used as part of a deflationary argument for a weak but relatively global version of scientific realism, a version that recognizes the place of conventions, goals, and contingencies in scientific representations, while maintaining that they are typically true in a clear and literal sense. By examining, in a naturalistic way, some relationships between maps and what they map, we question the scope and value of realist construals of maps-and (...)
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  13. Sergio Sismondo (2000). It's a Wonderful World. Biology and Philosophy 15 (1):103-106.
  14. Sergio Sismondo (2000). Island Biogeography and the Multiple Domains of Models. Biology and Philosophy 15 (2):239-258.
    This paper adopts a symmetrical approach tocontroversies over R.H. MacArthur and E.O. Wilson'sequilibrium model of island biogeography, in order toshow how different interpretations of the model dependupon different philosophical understandings of theapplication of models and theories. In particular,there are quite distinct domains to which the modelcould apply; in addition, some equivocation amongthese domains is important to the model's success.Therefore, apparently inconsistent interpretations,interpretations that fit into roughly instrumentalist,realist and rationalist conceptions of science, may bemutually supporting in practice. Descriptions ofscientific practice, then, (...)
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  15. Sergio Sismondo (1999). Models, Simulations, and Their Objects. Science in Context 12 (2).
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  16. Sergio Sismondo (1998). The Mapping Metaphor in Philosophy of Science. Cogito 12 (1):41-50.
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  17. Sergio Sismondo (1997). Deflationary Metaphysics and the Construction of Laboratory Mice. Metaphilosophy 28 (3):219-232.
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  18. Sergio Sismondo (1997). Modelling Strategies: Creating Autonomy for Biology's Theory of Games. History and Philosophy of the Life Sciences 19 (2):147 - 161.
    John Maynard Smith is the person most responsible for the use of game theory in evolutionary biology, having introduced and developed its major concepts, and later surveyed its uses. In this paper I look at some rhetorical work done by Maynard Smith and his co-author G.R. Price to make game theory a standard and common modelling tool for the evolutionary study of behavior. The original presentation of the ideas — in a 1973 Nature article — is frequently cited but almost (...)
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  19. Sergio Sismondo (1995). The Scientific Domains of Feminist Standpoints. Perspectives on Science 3 (1):49-65.
     
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  20. Sergio Sismondo (1992). The Structure Thirty Years Later: Refashioning a Constructivist Metaphysical Program. PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association 1992:300 - 312.
    The Thomas Kuhn of "The Structure of Scientific Revolutions" is often seen as an idealist or Neo-Kantian, as holding a constructivist as opposed to realist position. A close reading of the texts in question, keeping in mind Kuhn's interests as a historian, doesn't support this position, though it uncovers other interesting metaphysical commitments. In particular, Kuhn sees a degree of complexity in the world that entails that there will often be some conventionality in our theories. Some reasons for the readings (...)
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