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  1. Johanna Hanefeld, Virginia Bond, Janet Seeley, Shelley Lees & Nicola Desmond (2013). Considerations for a Human Rights Impact Assessment of a Population Wide Treatment for HIV Prevention Intervention. Developing World Bioethics 14 (3).
    Increasing attention is being paid to the potential of anti-retroviral treatment (ART) for HIV prevention. The possibility of eliminating HIV from a population through a universal test and treat intervention, where all people within a population are tested for HIV and all positive people immediately initiated on ART, as part of a wider prevention intervention, was first proposed in 2009. Several clinical trials testing this idea are now in inception phase. An intervention which relies on universally testing the entire population (...)
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  2. Andrew Vallely, Shelley Lees, Charles Shagi, Saidi Kapiga, Sheena McCormack & Richard Hayes (2012). Ethics, Justice and Community Participation in the Microbicides Development Programme (MDP) Phase III Trial in Mwanza, Tanzania. American Journal of Bioethics 12 (11):46-48.
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  3. Andrew Vallely, Shelley Lees, Charles Shagi, Stella Kasindi, Selephina Soteli, Natujwa Kavit, Lisa Vallely, Sheena McCormack, Robert Pool & Richard J. Hayes (2010). How Informed is Consent in Vulnerable Populations? Experience Using a Continuous Consent Process During the MDP301 Vaginal Microbicide Trial in Mwanza, Tanzania. BMC Medical Ethics 11 (1):10-.
    Background: HIV prevention trials conducted among disadvantaged vulnerable at-risk populations in developing countries present unique ethical dilemmas. A key concern in bioethics is the validity of informed consent for trial participation obtained from research subjects in such settings. The purpose of this study was to investigate the effectiveness of a continuous informed consent process adopted during the MDP301 phase III vaginal microbicide trial in Mwanza, Tanzania. Methods: A total of 1146 women at increased risk of HIV acquisition working as alcohol (...)
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  4. Andrew Vallely, Charles Shagi, Shelley Lees, Katherine Shapiro, Joseph Masanja, Lawi Nikolau, Johari Kazimoto, Selephina Soteli, Claire Moffat, John Changalucha, Sheena McCormack & Richard J. Hayes (2009). Microbicides Development Programme: Engaging the Community in the Standard of Care Debate in a Vaginal Microbicide Trial in Mwanza, Tanzania. BMC Medical Ethics 10 (1):17-.
    BackgroundHIV prevention research in resource-limited countries is associated with a variety of ethical dilemmas. Key amongst these is the question of what constitutes an appropriate standard of health care (SoC) for participants in HIV prevention trials. This paper describes a community-focused approach to develop a locally-appropriate SoC in the context of a phase III vaginal microbicide trial in Mwanza City, northwest Tanzania.MethodsA mobile community-based sexual and reproductive health service for women working as informal food vendors or in traditional and modern (...)
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