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  1. Steven Laureys, Baseline Brain Activity Fluctuations Predict Somatosensory Perception in Humans.
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  2. Olivia Gosseries, Erik Ziegler, Steven Laureys, Aurore Thibaut & Camille Chatelle, Spasticity After Stroke: Physiology, Assessment and Treatment.
    Background: Spasticity following a stroke occurs in about 30% of patients. The mechanisms underlying this disorder, however, are not well understood. Method: This review aims to define spasticity, describe hypotheses explaining its development after a stroke, give an overview of related neuroimaging studies as well as a description of the most common scales used to quantify the degree of spasticity and finally explore which treatments are currently being used to treat this disorder.
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  3. Steven Laureys, Supporting Online Material For.
    Patient To examine neural responses to aurally-presented sentences, a sparse imaging technique was used to minimize interference from scanner noise. The patient was played a single sentence (or noise-equivalent) in the 7.4s silent period before a single 1.6s scan with stimulus timing jittered relative to scan onset. There were 118 spoken sentences trials, 59 signal correlated noise trials, and an additional 60 silent trials for the purpose of monitoring data quality. The signal correlated noise stimuli had the same duration, spectral (...)
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  4. Athina Demertzi, Eric Racine, Marie-Aurélie Bruno, Didier Ledoux, Olivia Gosseries, Audrey Vanhaudenhuyse, Marie Thonnard, Andrea Soddu, Gustave Moonen & Steven Laureys (forthcoming). Pain Perception in Disorders of Consciousness: Neuroscience, Clinical Care, and Ethics in Dialogue. Neuroethics.
  5. Vanessa Charland-Verville, Jean-Pierre Jourdan, Marie Thonnard, Didier Ledoux, Anne-Francoise Donneau, Etienne Quertemont & Steven Laureys (2014). Near-Death Experiences in Non-Life-Threatening Events and Coma of Different Etiologies. Frontiers in Human Neuroscience 8.
  6. Melanie Boly, Anil K. Seth, Melanie Wilke, Paul Ingmundson, Bernard Baars, Steven Laureys, David Edelman & Naotsugu Tsuchiya (2013). Consciousness in Humans and Non-Human Animals: Recent Advances and Future Directions. Frontiers in Psychology 4.
    This joint article reflects the authors’ personal views regarding noteworthy advances in the neuroscience of consciousness in the last ten years, and suggests what we feel may be promising future directions. It is based on a small conference at the Samoset Resort in Rockport, Maine, USA, in July of 2012, organized by the Mind Science Foundation of San Antonio, Texas. Here, we summarize recent advances in our understanding of subjectivity in humans and other animals, including empirical, applied, technical and conceptual (...)
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  7. Athena Demertzi & Steven Laureys (2012). Where in the Brain is Pain? : Evaluating Painful Experiences in Non-Communicative Patients. In Sarah Richmond, Geraint Rees & Sarah J. L. Edwards (eds.), I Know What You're Thinking: Brain Imaging and Mental Privacy. Oxford University Press. 89.
  8. Lizette Heine, Andrea Soddu, Francisco Gómez, Audrey Vanhaudenhuyse, Luaba Tshibanda, Marie Thonnard, Vanessa Charland-Verville, Murielle Kirsch, Steven Laureys & Athena Demertzi (2012). Resting State Networks and Consciousness: Alterations of Multiple Resting State Network Connectivity in Physiological, Pharmacological, and Pathological Consciousness States. Frontiers in Psychology 3.
    In order to better understand the functional contribution of resting state activity to conscious cognition, we aimed to review increases and decreases in fMRI functional connectivity under physiological (sleep), pharmacological (anesthesia) and pathological altered states of consciousness, such as brain death, coma, vegetative state/unresponsive wakefulness syndrome, and minimally conscious state. The reviewed RSNs were the DMN, left and right executive control, salience, sensorimotor, auditory and visual networks. We highlight some methodological issues concerning resting state analyses in severely injured brains mainly (...)
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  9. Camille Chatelle, Steven Laureys, Steve Majerus, Caroline Schnakers, Paula M. Niedenthal, Martial Mermillod, Marcus Maringer & Ursula Hess (2010). Eye Gaze and Conscious Processing in Severely Brain-Injured Patients. Behavioral and Brain Sciences 33 (6):442.
    Niedenthal et al. discuss the importance of eye gaze in embodied simulation and, more globally, in the processing of emotional visual stimulation (such as facial expression). In this commentary, we illustrate the relationship between oriented eye movements, consciousness, and emotion by using the case of severely brain-injured patients recovering from coma (i.e., vegetative and minimally conscious patients).
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  10. John F. Stins & Steven Laureys (2009). Thought Translation, Tennis and Turing Tests in the Vegetative State. Phenomenology and the Cognitive Sciences 8 (3):361-370.
    Brain damage can cause massive changes in consciousness levels. From a clinical and ethical point of view it is desirable to assess the level of residual consciousness in unresponsive patients. However, no direct measure of consciousness exists, so we run into the philosophical problem of other minds. Neurologists often make implicit use of a Turing test-like procedure in an attempt to gain access to damaged minds, by monitoring and interpreting neurobehavioral responses. New brain imaging techniques are now being developed that (...)
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  11. Joseph J. Fins, Judy Illes, James L. Bernat, Joy Hirsch, Steven Laureys & Emily Murphy (2008). Neuroimaging and Disorders of Consciousness: Envisioning an Ethical Research Agenda. American Journal of Bioethics 8 (9):3 – 12.
    The application of neuroimaging technology to the study of the injured brain has transformed how neuroscientists understand disorders of consciousness, such as the vegetative and minimally conscious states, and deepened our understanding of mechanisms of recovery. This scientific progress, and its potential clinical translation, provides an opportunity for ethical reflection. It was against this scientific backdrop that we convened a conference of leading investigators in neuroimaging, disorders of consciousness and neuroethics. Our goal was to develop an ethical frame to move (...)
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  12. Joseph J. Fins, Judy Illes, James L. Bernat, Joy Hirsch, Steven Laureys & Emily Murphy (2008). Participants of the Working Meeting on Ethics, Neuroimaging and Limited States of Consciousness. Neuroimaging and Disorders of Consciousness: Envisioning an Ethical Research Agenda. Am J Bioethics 8 (9):3-12.
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  13. Mélanie Boly, Marie-Elisabeth Faymonville, Brent A. Vogt, Pierre Maquet & Steven Laureys (2007). Hypnotic Regulation of Consciousness and the Pain Neuromatrix. In Graham A. Jamieson (ed.), Hypnosis and Conscious States: The Cognitive Neuroscience Perspective. Oxford University Press. 15-27.
  14. Adrian M. Owen, Martin R. Coleman, Melanie Boly, Matthew H. Davis, Steven Laureys, Dietsje Jolles & John D. Pickard (2007). Response to Comments on "Detecting Awareness in the Vegetative State". Science 315 (5816).
  15. Adrian M. Owen, Martin R. Coleman, Melanie Boly, Matthew H. Davis, Steven Laureys & John D. Pickard (2007). Using Functional Magnetic Resonance Imaging to Detect Covert Awareness in the Vegetative State. Archives of Neurology 64 (8):1098-1102.
  16. Audrey Vanhaudenhuyse, Marie-Aurelie Bruno, Serge Bredart, Alain Plenevaux & Steven Laureys (2007). The Challenge of Disentangling Reportability and Phenomenal Consciousness in Post-Comatose States. Behavioral and Brain Sciences 30 (5-6):529-530.
    Determining whether or not noncommunicative patients are phenomenally conscious is a major clinical and ethical challenge. Clinical assessment is usually limited to the observation of these patients' motor responses. Recent neuroimaging technology and brain computer interfaces help clinicians to assess whether patients are conscious or not, and to avoid diagnostic errors.
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  17. Steven Laureys (2006). The Locked-in Syndrome: What is It Like to Be Conscious but Paralysed and Mute? In , Boundaries of Consciousness. Elsevier.
  18. S. Majerus, H. Gill-Thwaites, Kristin Andrews & Steven Laureys (2006). Behavioral Evaluation of Consciousness in Severe Brain Damage. In Steven Laureys (ed.), Boundaries of Consciousness. Elsevier.
  19. Pierre Maquet, P. Ruby, A. Maudoux, G. Albouy, V. Sterpenich, T. Dan-Vu, M. Desseilles, Melanie Boly, Fabien Perrin, Philippe Peigneux & Steven Laureys (2006). Human Cognition During Rem Sleep and the Activity Profile Within Frontal and Parietal Cortices. A Reappraisal of Functional Neuroimaging Data. In Steven Laureys (ed.), Boundaries of Consciousness. Elsevier.
  20. Adrian M. Owen, Martin R. Coleman, Melanie Boly, Matthew H. Davis, Steven Laureys, Dietsje Jolles & John D. Pickard (2006). Detecting Awareness in the Conscious State. Science 313:1402.
     
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  21. Fabien Perrin, Caroline Schnakers, Manuel Schabus, Christian Degueldre, Serge Goldman, Serge Brédart, Marie-Elisabeth E. Faymonville, Maurice Lamy, Gustave Moonen, André Luxen, Pierre Maquet & Steven Laureys (2006). Brain Response to One's Own Name in Vegetative State, Minimally Conscious State, and Locked-in Syndrome. Archives of Neurology 63 (4):562-569.
  22. E. Salmon, P. Ruby, D. Perani, E. Kalbe, Steven Laureys, S. Adam & F. Collette (2006). Two Aspects of Impaired Consciousness in Alzheimer's. In Steven Laureys (ed.), Boundaries of Consciousness. Elsevier.
     
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  23. Caroline Schnakers, Joseph Giacino, Kathleen Kalmar, Sonia Piret, Eduardo Lopez, Mélanie Boly, Richard Malone & Steven Laureys (2006). Does the FOUR Score Correctly Diagnose the Vegetative and Minimally Conscious States? Annals of Neurology 60 (6):744-745.
  24. B. A. Vogt & Steven Laureys (2006). Posterior Cingulate, Precuneal and Retrosplenial Cortices: Cytology and Components of the Neural Network Correlates of Consciousness. In Steven Laureys (ed.), Boundaries of Consciousness. Elsevier.
    Neuronal aggregates involved in conscious awareness are not evenly distributed throughout the CNS but comprise key components referred to as the neural network correlates of consciousness (NNCC). A critical node in this network is the posterior cingulate, precuneal, and retrosplenial cortices. The cytological and neurochemical composition of this region is reviewed in relation to the Brodmann map. This region has the highest level of cortical glucose metabolism and cytochrome c oxidase activity. Monkey studies suggest that the anterior thalamic projection likely (...)
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  25. Bernard J. Baars & Steven Laureys (2005). One, Not Two, Neural Correlates of Consciousness. Trends in Cognitive Sciences 9 (6):269.
  26. Arnaud Destrebecqz, Philippe Peigneux, Steven Laureys, Christian Degueldre, Guy Del Fiore, Joel Aerts, Andre Luxen, Martia Van Der Linden, Axel Cleeremans & Pierre Maquet (2005). The Neural Correlates of Implicit and Explicit Sequence Learning: Interacting Networks Revealed by the Process Dissociation Procedure. Learning and Memory 12 (5):480-490.
    In cognitive neuroscience, dissociating the brain networks that ing—has thus become one of the best empirical situations subtend conscious and nonconscious memories constitutes a through which to study the mechanisms of implicit learning, very complex issue, both conceptually and methodologically.
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  27. Steven Laureys (ed.) (2005). The Boundaries of Consciousness: Neurobiology and Neuropathology: Progress in Brain Research. Elsevier.
  28. Steven Laureys (2005). The Neural Correlate of (Un)Awareness: Lessons From the Vegetative State. Trends in Cognitive Sciences 9 (12):556-559.
  29. Steven Laureys & Serge Goldman (2004). Imagine Imaging Neural Activity in Crying Infants and in Their Caring Parents. Behavioral and Brain Sciences 27 (4):465-467.
    Soltis' paper contains little data on the underlying neural substrate of the discussed signal function of early infant crying – probably because there is amazingly little known about it. We here discuss the interest of functional neuroimaging as an objective measurement of brain activity in (1) early infants during crying and (2) parents hearing their offspring cry.
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  30. Steven Laureys, Adrian M. Owen & Nicholas D. Schiff (2004). Brain Function in Coma, Vegetative State, and Related Disorders. Lancet Neurology 3:537-546.
  31. Steven Laureys, Fabien Perrin & Marie-Elisabeth E. Faymonville (2004). Cerebral Processing in the Minimally Conscious State. Neurology 63 (5):916-918.
  32. Bernard J. Baars, Thomas Zoega Ramsoy & Steven Laureys (2003). Brain, Conscious Experience, and the Observing Self. Trends in Neurosciences 26 (12):671-5.
    Conscious perception, like the sight of a coffee cup, seems to involve the brain identifying a stimulus. But conscious input activates more brain regions than are needed to identify coffee cups and faces. It spreads beyond sensory cortex to frontoparietal association areas, which do not serve stimulus identification as such. What is the role of those regions? Parietal cortex support the ‘first person perspective’ on the visual world, unconsciously framing the visual object stream. Some prefrontal areas select and interpret conscious (...)
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  33. Arnaud Destrebecqz, Philippe Peigneux, Steven Laureys, Christian Degueldre, Guy Del Fiore, Joel Aerts, Andre Luxen, Martial van der Linden, Axel Cleeremans & Pierre Maquet (2003). Cerebral Correlates of Explicit Sequence Learning. Cognitive Brain Research 16 (3):391-398.
    Using positron emission tomography (PET) and regional cerebral blood flow (rCBF) measurements, we investigated the cerebral correlates of consciousness in a sequence learning task through a novel application of the Process Dissociation Procedure, a behavioral paradigm that makes it possible to separately assess conscious and unconscious contributions to performance. Results show that the metabolic response in the anterior cingulate / mesial prefrontal cortex (ACC / MPFC) is exclusively and specifically correlated with the explicit component of performance during recollection of a (...)
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  34. Steven Laureys, Marie-Elisabeth E. Faymonville & M. Ferring (2003). Differences in Brain Metabolism Between Patients in Coma, Vegetative State, Minimally Conscious State and Locked-in Syndrome. European Journal of Neurology 10.
  35. Steven Laureys, S. Majerus & Gustave Moonen, Assessing Consciousness in Critically Ill Patients.
     
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  36. Pierre Maquet, Steven Laureys, Philippe Peigneux, Sonia Fuchs, Christophe Petiau, Christophe Phillips, Joel Aerts, Guy Del Fiore, Christian Degueldre, Thierry Meulemans, Andre Luxen, Georges Franck, Martial Van Der Linden, Carlyle Smith & Axel Cleeremans (2000). Experience-Dependent Changes in Cerebral Activation During Human Rem Sleep. Nature Neuroscience 3 (8):831-36.
    Pierre Maquet1,2,6, Steven Laureys1,2, Philippe Peigneux1,2,3, Sonia Fuchs1, Christophe Petiau1, Christophe Phillips1,6, Joel Aerts1, Guy Del Fiore1, Christian Degueldre1, Thierry Meulemans3, André Luxen1, Georges Franck1,2, Martial Van Der Linden3, Carlyle Smith4 and Axel Cleeremans5.
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