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    T. M. Arnesen (2003). Quantifying Quality of Life for Economic Analysis: Time Out for Time Trade Off. Medical Humanities 29 (2):81-86.
    The “Time trade-off” (TTO), is the most widely used method to “quality adjust” life years for “QALYs” in cost utility analysis. In this paper we ask if it is theoretically likely that the TTO is valid for this use. The TTO consists in a trade off between longevity and quality of life. Firstly, we argue that it is impossible to control for all factors that may influence one’s willingness to sacrifice lifetime. Secondly, that longevity and quality of life are too (...)
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