We give a commentary on Newelski's suggestion or conjecture [8] that topological dynamics, in the sense of Ellis [3], applied to the action of a definable group $G(M)$ on its “external type space” $S_{G,\textit{ext}}(M)$, can explain, account for, or give rise to, the quotient $G/G^{00}$, at least for suitable groups in NIP theories. We give a positive answer for measure-stable (or $fsg$) groups in NIP theories. As part of our analysis we show the existence of “externally definable” generics (...) of $G(M)$ for measure-stable groups. We also point out that for $G$ definably amenable (in a NIP theory) $G/G^{00}$ can be recovered, via the Ellis theory, from a natural Ellis semigroup structure on the space of global $f$-generic types. (shrink)

We investigate definable topological dynamics of groups definable in an o‐minimal expansion of the field of reals. Assuming that a definable group G admits a model‐theoretic analogue of Iwasawa decomposition, namely the compact‐torsion‐free decomposition, we give a description of minimal subflows and the Ellis group of its universal definable flow in terms of this decomposition. In particular, the Ellis group of this flow is isomorphic to. This provides a range of counterexamples to a question by Newelski whether the (...) Ellis group is isomorphic to. We further extend the results to universal topological covers of definable groups, interpreted in a two‐sorted structure containing the o‐minimal sort and a sort for an abelian group. (shrink)

We interpret the basic notions of topological dynamics in the model-theoretic setting, relating them to generic types of definable group actions and their generalizations.

We study the flow of trigonalizable algebraic group acting on its type space, focusing on the problem raised in [17] of whether weakly generic types coincide with almost periodic types if the group has global definable f‐generic types, equivalently whether the union of minimal subflows of a suitable type space is closed. We shall give a description of f‐generic types of trigonalizable algebraic groups, and prove that every f‐generic type is almost periodic.

AssumeGis a group definable in a modelMof a stable theoryT. We prove that the semigroupSG of completeG-types overMis an inverse limit of some semigroups type-definable inMeq. We prove that the maximal subgroups ofSG are inverse limits of some definable quotients of subgroups ofG. We consider the powers of types in the semigroupSG and prove that in a way every type inSG is profinitely many steps away from a type in a subgroup ofSG.

A famous theorem by van der Waerden states the following: Given any finite coloring of the integers, one color contains arbitrarily long arithmetic progressions. Equivalently, for every q,k, there is an N = N(q,k) such that for every q-coloring of an interval of length N one color contains a progression of length k. An obvious question is what is the growth rate of N = N(q,k). Some proofs, like van der Waerden's combinatorial argument, answer this question directly, while the (...) class='Hi'>topological proof by Furstenberg and Weiss does not. We present an analysis of (Girard's variant of) Furstenberg and Weiss's proof based on monotone functional interpretation, both yielding bounds and providing a general illustration of proof mining in topological dynamics. The bounds do not improve previous results by Girard, but only—as is also revealed by the analysis—because the combinatorial proof and the topological dynamics proof in principle are identical. (shrink)

For G a group definable in some structure M, we define notions of “definable” compactification of G and “definable” action of G on a compact space X , where the latter is under a definability of types assumption on M. We describe the universal definable compactification of G as View the MathML source and the universal definable G-ambit as the type space SG. We also point out the existence and uniqueness of “universal minimal definable G-flows”, and discuss issues of amenability (...) and extreme amenability in this definable category, with a characterization of the latter. For the sake of completeness we also describe the universal compactification and universal G-ambit in model-theoretic terms, when G is a topological group. (shrink)

We give a model-theoretic treatment of the fundamental results of Kechris-Pestov-Todorčević theory in the more general context of automorphism groups of not necessarily countable structures. One of the main points is a description of the universal ambit as a certain space of types in an expanded language. Using this, we recover results of Kechris et al. (Funct Anal 15:106–189, 2005), Moore (Fund Math 220:263–280, 2013), Ngyuen Van Thé (Fund Math 222: 19–47, 2013), in the context of automorphism groups of not (...) necessarily countable structures, as well as Zucker (Trans Am Math Soc 368, 6715–6740, 2016). (shrink)

In order to solve the problem of node information loss during user matching in the existing user identification method of fixed community across the social network based on user topological relationship, Two-Stage User Identification Based on User Topology Dynamic Community Clustering algorithm is proposed. Firstly, we perform community clustering on different social networks, calculate the similarity between different network communities, and screen out community pairs with greater similarity. Secondly, two-way marriage matching is carried out for users between pairs of (...) communities with high similarity. Then, the dynamic community clustering was performed by resetting the different community clustering numbers. Finally, the iteration is repeated until no new matching user pairs are generated, or the set number of iterations is reached. Experiments conducted on real-world social networks Twitter-Foursquare datasets demonstrate that compared with the global user matching method and hidden label node method, the average accuracy of the proposed UIUTDC algorithm is improved by 33% and 26.8%, respectively. In the case of only user topology information, the proposed UIUTDC algorithm effectively improves the accuracy of identity recognition in practical applications. (shrink)

The language of linear temporal logic can be interpreted on the class of dynamic topological systems, giving rise to the intuitionistic temporal logic ${\sf ITL}^{\sf c}_{\Diamond \forall }$, recently shown to be decidable by Fernández-Duque. In this article we axiomatize this logic, some fragments, and prove completeness for several familiar spaces.

Dynamic Topological Logic ( ) is a modal logic which combines spatial and temporal modalities for reasoning about dynamic topological systems , which are pairs consisting of a topological space X and a continuous function f : X → X . The function f is seen as a change in one unit of time; within one can model the long-term behavior of such systems as f is iterated. One class of dynamic topological systems where the long-term (...) behavior of f is particularly interesting is that of minimal systems ; these are dynamic topological systems which admit no proper, closed, f -invariant subsystems. In such systems the orbit of every point is dense, which within translates into a non-trivial interaction between spatial and temporal modalities. This interaction, however, turns out to make the logic simpler, and while s in general tend to be undecidable, interpreted over minimal systems we obtain decidability, although not in primitive recursive time; this is the main result that we prove in this paper. We also show that interpreted over minimal systems is incomplete for interpretations on relational Kripke frames and hence does not have the finite model property; however it does have a finite non-deterministic quasimodel property. Finally, we give a set of formulas of which characterizes the class of minimal systems within the class of dynamic topological systems, although we do not offer a full axiomatization for the logic. (shrink)

Dynamic topological logic provides a context for studying the confluence of the topological semantics for S4, topological dynamics, and temporal logic. The topological semantics for S4 is based on topological spaces rather than Kripke frames. In this semantics, □ is interpreted as topological interior. Thus S4 can be understood as the logic of topological spaces, and □ can be understood as a topological modality. Topological dynamics studies the asymptotic properties (...) of continuous maps on topological spaces. Let a dynamic topological system be a topological space X together with a continuous function f. f can be thought of in temporal terms, moving the points of the topological space from one moment to the next. Dynamic topological logics are the logics of dynamic topological systems, just as S4 is the logic of topological spaces. Dynamic topological logics are defined for a trimodal language with an S4-ish topological modality □, and two temporal modalities, ○ and *, both interpreted using the continuous function f. In particular, ○ expresses f’s action on X from one moment to the next, and * expresses the asymptotic behaviour of f. (shrink)

Dynamic topological logic provides a context for studying the confluence of the topological semantics for S4, topological dynamics, and temporal logic. The topological semantics for S4 is based on topological spaces rather than Kripke frames. In this semantics, □ is interpreted as topological interior. Thus S4 can be understood as the logic of topological spaces, and □ can be understood as a topological modality. Topological dynamics studies the asymptotic properties (...) of continuous maps on topological spaces. Let a dynamic topological system be a topological space X together with a continuous function f. f can be thought of in temporal terms, moving the points of the topological space from one moment to the next. Dynamic topological logics are the logics of dynamic topological systems, just as S4 is the logic of topological spaces. Dynamic topological logics are defined for a trimodal language with an S4-ish topological modality □ , and two temporal modalities, ○ and * , both interpreted using the continuous function f. In particular, ○ expresses f’s action on X from one moment to the next, and * expresses the asymptotic behaviour of f. (shrink)

Dynamic topological logic combines topological and temporal modalities to express asymptotic properties of dynamic systems on topological spaces. A dynamic topological model is a triple 〈X ,f , V 〉, where X is a topological space, f : X → X a continuous function and V a truth valuation assigning subsets of X to propositional variables. Valid formulas are those that are true in every model, independently of X or f. A natural problem that arises (...) is to identify the logics obtained on familiar spaces, such as . It [9] it was shown that any satisfiable formula could be satisfied in some for n large enough, but the question of how the logic varies with n remained open.In this paper we prove that any fragment of DTL that is complete for locally finite Kripke frames is complete for . This includes DTL○; it also includes some larger fragments, such as DTL1, where “henceforth” may not appear in the scope of a topological operator. We show that satisfiability of any formula of our language in a locally finite Kripke frame implies satisfiability in by constructing continuous, open maps from the plane into arbitrary locally finite Kripke frames, which give us a type of bisimulation. We also show that the results cannot be extended to arbitrary formulas of DTL by exhibiting a formula which is valid in but not in arbitrary topological spaces. (shrink)

The topological semantics for modal logic interprets a standard modal propositional language in topological spaces rather than Kripke frames: the most general logic of topological spaces becomes S4. But other modal logics can be given a topological semantics by restricting attention to subclasses of topological spaces: in particular, S5 is logic of the class of almost discrete topological spaces, and also of trivial topological spaces. Dynamic Topological Logic interprets a modal language enriched (...) with two unary temporal connectives, next and henceforth. DTL interprets the extended language in dynamic topological systems: a DTS is a topological space together with a continuous function used to interpret the temporal connectives. In this paper, we axiomatize four conservative extensions of S5, and show them to be the logic of continuous functions on almost discrete spaces, of homeomorphisms on almost discrete spaces, of continuous functions on trivial spaces and of homeomorphisms on trivial spaces. (shrink)

Dynamic topological logic provides a context for studying the confluence of the topological semantics for S4, topological dynamics, and temporal logic. The topological semantics for S4 is based on topological spaces rather than Kripke frames. In this semantics, is interpreted as topological interior. Thus S4 can be understood as the logic of topological spaces, and can be understood as a topological modality. Topological dynamics studies the asymptotic properties of continuous (...) maps on topological spaces. Let a dynamic topological system be a topological space X together wError: Corrupted memory profileError: read ICCBased color space profile errorith a continuous function f. f can be thought of in temporal terms, moving the points of the topological space from one moment to the next. Dynamic topological logics are the logics of dynamic topological systems, just as S4 is the logic of topological spaces. Dynamic topological logics are defined for a trimodal language with an S4-ish topological modality, and two temporal modalities, and ∗, both interpreted using the continuous function. (shrink)

Dynamic Topological Logic ( $\mathcal{DTL}$ ) is a modal framework for reasoning about dynamical systems, that is, pairs 〈X, f〉 where X is a topological space and f: X → X a continuous function. In this paper we consider the case where X is a metric space. We first show that any formula which can be satisfied on an arbitrary dynamic topological system can be satisfied on one based on a metric space; in fact, this space can (...) be taken to be countable and have no isolated points. Since any metric space with these properties is homeomorphic to the set of rational numbers, it follows that any satisfiable formula can be satisfied on a system based on $\mathbb{Q}$ . We then show that the situation changes when considering complete metric spaces, by exhibiting a formula which is not valid in general but is valid on the class of systems based on a complete metric space. While we do not attempt to give a full characterization of the set of valid formulas on this class we do give a relative completeness result; any formula which is satisfiable on a dynamical system based on a complete metric space is also satisfied on one based on the Cantor space. (shrink)

We investigate computational properties of propositional logics for dynamical systems. First, we consider logics for dynamic topological systems (W.f), fi, where W is a topological space and f a homeomorphism on W. The logics come with ‘modal’ operators interpreted by the topological closure and interior, and temporal operators interpreted along the orbits {w, f(w), f2 (w), ˙˙˙} of points w ε W. We show that for various classes of topological spaces the resulting logics are not recursively (...) enumerable (and so not recursively axiomatisable). This gives a ‘negative’ solution to a conjecture of Kremer and Mints. Second, we consider logics for dynamical systems (W, f), where W is a metric space and f and isometric function. The operators for topological interior/closure are replaced by distance operators of the form ‘everywhere/somewhere in the ball of radius a, ‘for a ε Q +. In contrast to the topological case, the resulting logic turns out to be decidable, but not in time bounded by any elementary function. (shrink)

Dynamical systems are mathematical objects meant to formally capture the evolution of deterministic systems. Although no topological constraint is usually imposed on their state spaces, there is prima facie evidence that the topological properties of dynamical systems might naturally depend on their dynamical features. This paper aims to prepare the grounds for a systematic investigation of such dependence, by exploring how the underlying dynamics might naturally induce a corresponding topology.

Dynamic Topological Logic () is a combination of , under its topological interpretation, and the temporal logic interpreted over the natural numbers. is used to reason about properties of dynamical systems based on topological spaces. Semantics are given by dynamic topological models, which are tuples , where is a topological space, f a function on X and V a truth valuation assigning subsets of X to propositional variables. Our main result is that the set of (...) valid formulas of over spaces with continuous functions is recursively enumerable. We show this by defining alternative semantics for . Under standard semantics, is not complete for Kripke frames. However, we introduce the notion of a non-deterministic quasimodel, where the function f is replaced by a binary relation g assigning to each world multiple temporal successors. We place restrictions on the successors so that the logic remains unchanged; under these alternative semantics, becomes Kripke-complete. We then apply model-search techniques to enumerate the set of all valid formulas. (shrink)

In “Topology of Balasaguni’s Kutadgu Bilig: Thinking the Between,” Onur Karamercan focuses on the philosophical dimension of Kutadgu Bilig, a poetic work of Yūsuf Balasaguni, an 11th century Central Asian thinker, poet, and statesman. Karamercan pays special attention to the meaning of betweenness and, in the first step of his argument, discusses the hermeneutic and topological implications of the between, distingushing the dynamic sense of betweenness from a static sense of in-betweenness. He then moves on to analyze Balasaguni’s notion (...) of language, which he interprets as an early critique of the instrumental account of language and, by examining several selected fragments from Kutadgu Bilig, illustrates Balasaguni’s designation of language as an inexhaustible phenomenon. In the process, he also points to the possible parallels between Balasaguni’s and Heidegger’s ideas of language. In the final section of the article, building on his argument, Karamercan thematizes the margins of Turkic languages and of Islamic philosophy, suggesting that they need to be reexamined. He problematizes the very meaning of Asia itself by decentering what he calls “its internal East–West antagonism” and puts forth instead a framework based on in-betweenness reinterpreted from a topological perspective, proposing it as an alternative view which might help us make sense of the hermeneutic neighborhoods of Asian philosophies. (shrink)

We address the biological dynamics problem of the persistence of several species in conditions of non-existence of an equilibrium, including an example of stabilization by predation and the very controversial “competitive exclusion”. We give normal forms for various examples of such persistence and comments on the involved topology, which implies the presence of exceptional heteroclinic connections binding equilibria on the boundary.

Dynamic topological logic is a multi-modal logic that was introduced for reasoning about dynamic topological systems, i.e. structures of the form $\langle{\mathfrak{X}, f}\rangle $, where $\mathfrak{X}$ is a topological space and $f$ is a continuous function on it. The problem of finding a complete and natural axiomatization for this logic in the original tri-modal language has been open for more than one decade. In this paper, we give a natural axiomatization of $\textsf{DTL}$ and prove its strong completeness (...) with respect to the class of all dynamic topological systems. Our proof system is infinitary in the sense that it contains an infinitary derivation rule with countably many premises and one conclusion. It should be remarked that $\textsf{DTL}$ is semantically non-compact, so no finitary proof system for this logic could be strongly complete. Moreover, we provide an infinitary axiomatic system for the logic ${\textsf{DTL}}_{\mathcal{A}}$, i.e. the $\textsf{DTL}$ of Alexandrov spaces, and show that it is strongly complete with respect to the class of all dynamical systems based on Alexandrov spaces. (shrink)

So-called ‘distinctively mathematical explanations’ (DMEs) are said to explain physical phenomena, not in terms of contingent causal laws, but rather in terms of mathematical necessities that constrain the physical system in question. Lange argues that the existence of four or more equilibrium positions of any double pendulum has a DME. Here we refute both Lange’s claim itself and a strengthened and extended version of the claim that would pertain to any n-tuple pendulum system on the ground that such explanations are (...) actually causal explanations in disguise and their associated modal conditionals are not general enough to explain the said features of such dynamical systems. We argue and show that if circumscribing the antecedent for a necessarily true conditional in such explanations involves making a causal analysis of the problem, then the resulting explanation is not distinctively mathematical or non-causal. Our argument generalises to other dynamical systems that may have purported DMEs analogous to the one proposed by Lange, and even to some other counterfactual accounts of non-causal explanation given by Reutlinger and Rice. (shrink)

Dynamic Topological Logic (DFH) is a multimodal system for reasoning about dynamical systems. It is defined semantically and, as such, most of the work done in the field has been model-theoretic. In particular, the problem of finding a complete axiomatization for the full language of DFH over the class of all dynamical systems has proven to be quite elusive. Here we propose to enrich the language to include a polyadic topological modality, originally introduced by Dawar and Otto in (...) a different context. We then provide a sound axiomatization for DFH over this extended language, and prove that it is complete. The polyadic modality is used in an essential way in our proof. (shrink)

A novel conceptual framework is introduced for the Complexity Levels Theory in a Categorical Ontology of Space and Time. This conceptual and formal construction is intended for ontological studies of Emergent Biosystems, Super-complex Dynamics, Evolution and Human Consciousness. A claim is defended concerning the universal representation of an item’s essence in categorical terms. As an essential example, relational structures of living organisms are well represented by applying the important categorical concept of natural transformations to biomolecular reactions and relational structures (...) that emerge from the latter in living systems. Thus, several relational theories of living systems can be represented by natural transformations of organismic, relational structures. The ascent of man and other living organisms through adaptation, is viewed in novel categorical terms, such as variable biogroupoid representations of evolving species. Such precise but flexible evolutionary concepts will allow the further development of the unifying theme of local-to-global approaches to highly complex systems in order to represent novel patterns of relations that emerge in super- and ultra-complex systems in terms of compositions of local procedures. Solutions to such local-to-global problems in highly complex systems with ‘broken symmetry’ might be possible to be reached with the help of higher homotopy theorems in algebraic topology such as the generalized van Kampen theorems (HHvKT). Categories of many-valued, Łukasiewicz-Moisil (LM) logic algebras provide useful concepts for representing the intrinsic dynamic ‘asymmetry’ of genetic networks in organismic development and evolution, as well as to derive novel results for (non-commutative) Quantum Logics. Furthermore, as recently pointed out by Baianu and Poli (Theory and applications of ontology, vol 1. Springer, Berlin, in press), LM-logic algebras may also provide the appropriate framework for future developments of the ontological theory of levels with its complex/entangled/intertwined ramifications in psychology, sociology and ecology. As shown in the preceding two papers in this issue, a paradigm shift towards non-commutative, or non-Abelian, theories of highly complex dynamics—which is presently unfolding in physics, mathematics, life and cognitive sciences—may be implemented through realizations of higher dimensional algebras in neurosciences and psychology, as well as in human genomics, bioinformatics and interactomics. (shrink)

A novel conceptual framework is introduced for the Complexity Levels Theory in a Categorical Ontology of Space and Time. This conceptual and formal construction is intended for ontological studies of Emergent Biosystems, Super-complex Dynamics, Evolution and Human Consciousness. A claim is defended concerning the universal representation of an item’s essence in categorical terms. As an essential example, relational structures of living organisms are well represented by applying the important categorical concept of natural transformations to biomolecular reactions and relational structures (...) that emerge from the latter in living systems. Thus, several relational theories of living systems can be represented by natural transformations of organismic, relational structures. The ascent of man and other living organisms through adaptation, is viewed in novel categorical terms, such as variable biogroupoid representations of evolving species. Such precise but flexible evolutionary concepts will allow the further development of the unifying theme of local-to-global approaches to highly complex systems in order to represent novel patterns of relations that emerge in super- and ultra-complex systems in terms of compositions of local procedures. Solutions to such local-to-global problems in highly complex systems with ‘broken symmetry’ might be possible to be reached with the help of higher homotopy theorems in algebraic topology such as the generalized van Kampen theorems (HHvKT). Categories of many-valued, Łukasiewicz-Moisil (LM) logic algebras provide useful concepts for representing the intrinsic dynamic ‘asymmetry’ of genetic networks in organismic development and evolution, as well as to derive novel results for (non-commutative) Quantum Logics. Furthermore, as recently pointed out by Baianu and Poli (Theory and applications of ontology, vol 1. Springer, Berlin, in press), LM-logic algebras may also provide the appropriate framework for future developments of the ontological theory of levels with its complex/entangled/intertwined ramifications in psychology, sociology and ecology. As shown in the preceding two papers in this issue, a paradigm shift towards non-commutative, or non-Abelian, theories of highly complex dynamics—which is presently unfolding in physics, mathematics, life and cognitive sciences—may be implemented through realizations of higher dimensional algebras in neurosciences and psychology, as well as in human genomics, bioinformatics and interactomics. (shrink)

A topological inevitability of early developmental events through the use of classical topological concepts is discussed. Topological dynamics of forms and maps in embryo development are presented. Forms of a developing organism such as cell sets and closed surfaces are topological objects. Maps (or mathematical functions) are additional topological constructions in these objects and include polarization, singularities and curvature. Topological visualization allows us to analyze relationships that link local morphogenetic processes and integral developmental (...) structures and also to find stable spatio-temporal topological characteristics that are invariant for a taxonomic group. The application of topological principles reveals a topological imperative: certain topological rules define and direct embryogenesis. A topological stability of embryonic morphogenesis is proposed and a topological scenario of developmental and evolutionary transformations is presented. (shrink)

We reformulate a key definition given by Wáng and Ågotnes to provide semantics for public announcements in subset spaces. More precisely, we interpret the precondition for a public announcement of ???? to be the “local truth” of ????, semantically rendered via an interior operator. This is closely related to the notion of ???? being “knowable”. We argue that these revised semantics improve on the original and offer several motivating examples to this effect. A key insight that emerges is the crucial (...) role of topological structure in this setting. Finally, we provide a simple axiomatization of the resulting logic and prove completeness. (shrink)

In a series of recent papers, two of which appeared in this journal, a group of philosophers, physicists, and climate scientists have argued that something they call the `hawkmoth effect' poses insurmountable difficulties for those who would use non-linear models, including climate simulation models, to make quantitative predictions or to produce `decision-relevant probabilites.' Such a claim, if it were true, would undermine much of climate science, among other things. Here, we examine the two lines of argument the group has used (...) to support their claims. The first comes from a set of results in dynamical systems theory associated with the concept of `structural stability.' The second relies on a mathematical demonstration of their own, using the logistic equation, that they present using a hypothetical scenario involving two apprentices of Laplace's omniscient demon. We prove two theorems that are relevant to their claims, and conclude that both of these lines of argument fail. There is nothing out there that comes close to matching the charac. (shrink)

Stalnaker, 169–199 2006) introduced a combined epistemic-doxastic logic that can formally express a strong concept of belief, a concept of belief as ‘subjective certainty’. In this paper, we provide a topological semantics for belief, in particular, for Stalnaker’s notion of belief defined as ‘epistemic possibility of knowledge’, in terms of the closure of the interior operator on extremally disconnected spaces. This semantics extends the standard topological interpretation of knowledge with a new topological semantics for belief. We prove (...) that the belief logic KD45 is sound and complete with respect to the class of extremally disconnected spaces and we compare our approach to a different topological setting in which belief is interpreted in terms of the derived set operator. We also study belief revision as well as belief dynamics by providing a topological semantics for conditional belief and belief update modalities, respectively. Our setting based on extremally disconnected spaces, however, encounters problems when extended with dynamic updates. We then propose a solution consisting in interpreting belief in a similar way based on hereditarily extremally disconnected spaces, and axiomatize the belief logic of hereditarily extremally disconnected spaces. Finally, we provide a complete axiomatization of the logic of conditional belief and knowledge, as well as a complete axiomatization of the corresponding dynamic logic. (shrink)

Male sexual arousal (SA) has been known as a multidimensional experience involving closely interrelated and coordinated neurobehavioral components that rely on widespread brain regions. Recent functional neuroimaging studies have shown relation between abnormal/altered dynamics in these circuits and male sexual dysfunction. However, alterations in the topological1 organization of structural brain networks in male sexual dysfunction are still unclear. Here, we used graph theory2 to investigate the topological properties of large-scale structural brain networks, which were constructed using inter-regional correlations (...) of cortical thickness between 78 cortical regions (subcortical regions were not included due to the used cortical surface model) in 40 patients with psychogenic erectile dysfunction (pED) and 39 normal controls. Compared with normal controls, pED patients exhibited a less optimal global topological organization with reduced global and increased local efficiencies. Our results suggest disrupted neural integration among distant brain regions in pED patients, consistent with previous reports of impaired white matter structure and abnormal functional integrity in pED. Additionally, disrupted global network topology in pED was observed to be primarily relevant to altered subnetwork and nodal properties within the networks mediating the cognitive, motivational and inhibitory processes of male SA, possibly indicating disrupted integration of these networks in the whole brain networks and might account for pED patients’ abnormal cognitive, motivational and inhibitory processes for male SA. In total, our findings provide evidence for disrupted integrity in large-scale brain networks underlying the neurobehavioral processes of male SA in pED and provide new insights into the understanding of the pathophysiological mechanisms of pED. (shrink)