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Ute Deichmann [31]U. Deichmann [16]
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Profile: Ute Deichmann (Ben-Gurion University of the Negev, University of Cologne)
  1.  68
    Ute Deichmann, Schuster Stefan, Mazat Jean-Pierre & Athel Cornish-Bowden (2013). Commemorating the 1913 Michaelis--Menten Paper Die Kinetik der Invertinwirkung: Three Perspectives. FEBS 281 (2):435-463.
    Methods and equations for analysing the kinetics of enzyme-catalysed reactions were developed at the beginning of the 20th century in two centres in particular; in Paris, by Victor Henri, and, in Berlin, by Leonor Michaelis and Maud Menten. Henri made a detailed analysis of the work in this area that had preceded him, and arrived at a correct equation for the initial rate of reaction. However, his approach was open to the important objection that he took no account of the (...)
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  2.  5
    U. Deichmann (2004). Early Responses to Avery Et Al.'S Paper on DNA as Hereditary Material. Historical Studies in the Physical and Biological Sciences 34 (2):207-232.
    Avery’s et al. ’s 1944 paper provides the first direct evidence of DNA having gene-like properties and marks the beginning of a new phase in early molecular genetics (with a strong focus on chemistry and DNA). The study of its reception shows that on the whole, Avery’s results were immediately appreciated and motivated new research on transformation, the chemical nature of DNA’s biological specificity and bacteria genetics. It shows, too, that initial problems of transferring transformation to other systems and prominent (...)
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  3.  23
    Ute Deichmann (2010). Gemmules and Elements: On Darwin's and Mendel's Concepts and Methods in Heredity. [REVIEW] Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 41 (1):85-112.
    Inheritance and variation were a major focus of Charles Darwin’s studies. Small inherited variations were at the core of his theory of organic evolution by means of natural selection. He put forward a developmental theory of heredity (pangenesis) based on the assumption of the existence of material hereditary particles. However, unlike his proposition of natural selection as a new mechanism for evolutionary change, Darwin’s highly speculative and contradictory hypotheses on heredity were unfruitful for further research. They attempted to explain many (...)
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  4.  2
    Ute Deichmann (2016). Chromatin: Its History, Current Research, and the Seminal Researchers and Their Philosophy. Perspectives in Biology and Medicine 58 (2):143-164.
    Eukaryotic genomes are packaged into a nucleoprotein complex known as chromatin. The term was introduced in 1879 by German cytologist Walther Flemming. While observing the processes of mitosis in a light microscope, Flemming coined the term to describe the easily stainable threads in the nucleus. He predicted that it would not have a long life: “The word chromatin may serve until its chemical nature is known, and meanwhile stands for that substance in the cell nucleus which is readily stained”. However, (...)
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  5.  21
    Ute Deichmann (2014). The Concept of the Causal Role of Chromosomes and Genes in Heredity and Development: Opponents From Darwin to Lysenko. Perspectives in Biology and Medicine 57 (1):57-77.
    A recent cover of the German news magazine Der Spiegel announced: “Victory over Genes. Smarter, healthier, happier: How we can outwit our genome” (2010). The magazine’s article, instead, emphasizes the importance of epigenetics. According to Florian Maderspacher (2010), who reprinted the cover in his editorial in Current Biology, the relief or “schadenfreude” about the apparent victory over genes—which the cover, the article, and commentaries to it reveal—is, in part, a German phenomenon. It echoes “a latent anti-scientific attitude in parts of (...)
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  6. Ulrich Charpa & Ute Deichmann (2004). Vertrauensvorschuß und wissenschaftliches Fehlhandeln — Eine reliabilistische Modellierung der Fälle Abderhalden, Goldschmidt, Moewus und Waldschmidt-Leitz†. Berichte Zur Wissenschaftsgeschichte 27 (3):187-204.
    Reliabilist philosophy of science considers scientific misconduct a transgression against the principles of good cognitive practice. Good practice in research is characterised by the reliability, efficiency and fertility of the cognitive processes involved. The reliabilist approach is closely connected to the idea of mutual cognitive dependency of the research community. Trust in the testimony of others is not an inevitable but a favouring factor of scientific progress — and misconduct damages the testimonial chain, respectively the principle of trustworthiness. Within the (...)
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  7.  6
    Ute Deichmann (2009). Chemistry and the Engineering of Life Around 1900: Research and Reflections by Jacques Loeb. Biological Theory 4 (4):323-332.
    Dissatisfied with the descriptive and speculative methods of evolutionary biology of his time, the physiologist Jacques Loeb , best known for his “engineering” approach to biology, reflected on the possibilities of artificially creating life in the laboratory. With the objective of experimentally tackling one of the crucial questions of organic evolution, i.e., the origin of life from inanimate matter, he rejected claims made by contemporary scientists of having produced artificial life through osmotic growth processes in inorganic salt solutions. According to (...)
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  8.  2
    Ute Deichmann (2008). Challenging the Protein Dogma of the Gene: Oswald T. Avery – a Revolutionary Conservative. In Oren Harman & Michael Dietrich (eds.), Rebels, Mavericks, and Heretics in Biology. Yale University Press
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  9.  8
    Ute Deichmann (1996). Biologists Under Hitler. Harvard University Press.
    A revised and enlarged version of Biologen unter Hitler, translated by Thomas Dunlap.
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  10.  1
    Ute Deichmann (2016). Dedication. Perspectives in Biology and Medicine 58 (2):141-142.
    We dedicate this special section to the memory of Eric H. Davidson, who died on the first of September 2015. Though he had been seriously ill for many years, his death was unexpected and a great shock for us.We dedicate the section, first, to a great scientist who passionately pursued the idea of a mechanistic explanation of development and evolution. Eric was a pioneer in the molecular biology of development and its relationship to evolution. One of the first to suggest (...)
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  11.  4
    U. Deichmann (2002). Emigration, Isolation and the Slow Start of Molecular Biology in Germany. Studies in History and Philosophy of Science Part C 33 (3):449-471.
    Until the 1930s Germany had been the international leader in biochemistry, chemistry, and areas of biology. After WWII, however, molecular biology as a new interdisciplinary scientific enterprise was scarcely represented in Germany for almost 20 years. Three major reasons for the low performance of molecular biology are discussed: first, the forced emigration of Jewish scientists after 1933, which not only led to the expulsion of future distinguished molecular biologists, but also to a strong decline of ''dynamic biochemistry'', a field which (...)
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  12.  15
    Ute Deichmann (2012). Beyond Popper and Polanyi: Leonor Michaelis, a Critical and Passionate Pioneer of Research at the Interface of Medicine, Enzymology, and Physical Chemistry. Perspectives in Biology and Medicine 55 (4):612-626.
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  13.  4
    Ute Deichmann (1999). The Expulsion of Jewish Chemists and Biochemists From Academia in Nazi Germany. Perspectives on Science 7 (1):1-86.
    In contrast to anti-Jewish campaigns at German universities in the 19th century, which met with opposition from liberal scholars, among them prominent chemists, there was no public reaction to the dismissals in 1933. Germany had been an international leader in chemistry until the 1930s. Due to a high proportion of Jewish physicists, chemistry was strongly affected by the expulsion of scientists. Organic and inorganic chemistry were least affected, while biochemistry suffered most. Polymer chemistry and quantum chemistry, of minor importance among (...)
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  14.  4
    U. Deichmann & B. Muller-Hill (1998). The Fraud of Abderhalden's Enzymes. Nature 393 (6681):109-111.
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  15.  12
    Ute Deichmann (2013). Crystals, Colloids, or Molecules?: Early Controversies About the Origin of Life and Synthetic Life. Perspectives in Biology and Medicine 55 (4):521-542.
    In Goethe's Faust, the poet refers to alchemists' widespread ideas on artificial creation of life in the laboratory. In Faust, such an attempt was not successful: the little man,Homunculus, created by the scholar Wagner through crystallization, was a pure spirit; his form and light disappeared in an attempt to become real life. According to Goethe, life was obviously not a crystal, and he pointed to decisive differences between crystals and organic beings, the latter for example elaborating their food into clear-cut (...)
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  16.  20
    Ute Deichmann (2007). “Molecular” Versus “Colloidal”: Controversies in Biology and Biochemistry, 1900–1940. Bulletin for the History of Chemistry 32 (2):105-118.
    OUTSTANDING PAPER AWARD, Division of the History of Chemistry, American Chemical Society.
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  17.  2
    U. Deichmann (2002). Chemists and Biochemists During the National Socialist Era. Angewandte Chemie - International Edition 41 (8):1310-1328.
    Chemistry and biochemistry in Germany was notably affected by the dismissal and emigration of Jewish scientists. The expulsion of Jewish scientists aided to significantly reduce the international regard for German science, particularly in biochemistry, physical chemistry, and quantum chemistry, after 1945. In most cases remaining scientists adjusted quickly after 1933 to the new political circumstances, with a few exceptions. A number of them even actively supported the politics of National Socialism. This fact as well as the common stance to forget (...)
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  18.  2
    U. Deichmann (2011). Early 20th-Century Research at the Interfaces of Genetics, Development, and Evolution: Reflections on Progress and Dead Ends. Developmental Biology 357 (1):3-12.
    Three early 20th-century attempts at unifying separate areas of biology, in particular development, genetics, physiology, and evolution, are compared in regard to their success and fruitfulness for further research: Jacques Loeb’s reductionist project of unifying approaches by physico-chemical explanations; Richard Goldschmidt’s anti-reductionist attempts to unify by integration; and Sewall Wright’s combination of reductionist research and vision of hierarchical genetic systems. Loeb’s program, demanding that all aspects of biology, including evolution, be studied by the methods of the experimental sciences, proved highly (...)
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  19.  6
    U. Deichmann & M. Morange (2011). The Origin of Life: Scientific, Historical and Philosophical Perspective. History and Philosophy of the Life Sciences 34 (3):337-339.
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  20.  10
    Ute Deichmann (2011). Michael Polanyi on Scientific Authority and His Criticism of Popper and Russell. Leo Baeck Institute Year Book 56 (1):249-268.
    This article analyzes, Polanyi’s notion of authority in science and his criticism of Popper and Russell. It uses the history of early genetics and neo-Darwinism in order to examine the fruitfulness of Polanyi's concepts for an understanding of the history of biology. It discusses the responsibility of scientists in influential positions and shows that scientific authority is – as is criticism – indispensable for progress.
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  21.  17
    Ute Deichmann (1999). The Expulsion of Jewish Biochemists From Academia in Nazi Germany. Perspectives on Science 7 (1):1-86.
    : In contrast to anti-Jewish campaigns at German universities in the 19th century, which met with opposition from liberal scholars, among them prominent chemists, there was no public reaction to the dismissals in 1933. Germany had been an international leader in (bio-)chemistry until the 1930s. Due to a high proportion of Jewish physicists, (bio-)chemistry was strongly affected by the expulsion of scientists. Organic and inorganic chemistry were least affected, while biochemistry suffered most. Polymer chemistry and quantum chemistry, of minor importance (...)
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  22.  5
    Ute Deichmann, Michel Morange & Anthony S. Travis (2013). Editors' Introduction to Special Issue. Perspectives in Biology and Medicine 55 (4):470-472.
    In this second decade of the 21st century, we find the pervasive influence of synthetic biology everywhere, not only in research laboratories, but also in the discourses of politicians and ethicists. Despite its ubiquity, the precise meaning of the notions of "synthetic biology" and "synthetic life," as well as their history, potential, and risks, remain obscure not only to the layperson, but also to most biologists.The aim of this special issue is twofold. First, it is intended to help the reader (...)
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  23.  7
    U. Deichmann (2008). Different Methods and Metaphysics in Early Molecular Genetics - A Case of Disparity of Research? History and Philosophy of the Life Sciences 30 (1):53-78.
    The encounter between two fundamentally different approaches in seminal research in molecular biology-the problems, aims, methods and metaphysics - is delineated and analyzed. They are exemplified by the microbiologist Oswald T. Avery who, in line with the reductionist mechanistic metaphysics of Jacques Loeb, attempted to explain basic life phenomena through chemistry; and the theoretical physicist Max Delbrück who, influenced by Bohr’s antimechanistic views, preferred to explain these phenomena without chemistry. Avery’s and Delbrück’s most important studies took place concurrently. Thus analysis (...)
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  24.  4
    U. Deichmann (1996). Genetics in Germany. [Review Of: Harwood J, Styles of Scientific Thought: The German Genetics Community, 1900-1933. Chicago: University of Chicago Press, 1993]. [REVIEW] British Journal for the History of Science 29 (100 Pt 1):83-87.
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  25.  4
    Rony Armon, Ulrich Charpa, Eric Davidson, Ute Deichmann, Raphael Falk, John Glass, Shimon Glick, Manfred Laubichler, Michel Morange, Isaac, Addy Pross, Siegfried Roth & Varda Shoshan-Barmatz (2012). Final Discussion: Issues and Challenges for the Future. Perspectives in Biology and Medicine 55 (4):608-611.
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  26.  2
    U. Chapra & U. Deichmann (2008). Jewish Scientists as Geniuses and Epigones: Scientific Practice and Attitudes Towards Albert Einstein, Ferdinand Cohn, Richard Goldschmidt. Studia Rosenthaliana 40:75-108.
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  27.  1
    Rony Armon, Ulrich Charpa, Eric Davidson, Ute Deichmann, Raphael Falk, John Glass, Shimon Glick, Manfred Laubichler, Michel Morange & Isaac Yanni Nevo (2012). Final Discussion: Issues and Challenges for the Future. Perspectives in Biology and Medicine 55 (4):608-611.
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  28.  3
    U. Deichmann (2007). Collective Phenomena and the Neglect of Molecules: A Historical Outlook on Biology. History and Philosophy of the Life Sciences 29 (1):83-86.
    The article recalls the anti-molecular transformation of biology 100 hundred years ago. The author recounts protein chemist Wolfgang Pauli’s announcement of a new era of biomedical research in 1905. Colloidal chemistry was supposed to be the center of the era described by Pauli. The author discusses the aspects that remained from the three decades in which colloidal science exerted a great influence on biological and biochemical research.
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  29.  4
    Ute Deichmann & Anthony S. Travis (2010). Special Section: Darwinism and Scientific Practice in Historical Perspective. [REVIEW] Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 41 (1):55-60.
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  30.  1
    Ute Deichmann (1999). Germany's Forgotten War. [REVIEW] Nature 401 (6752):425.
    Reviews the book 'The Nazi War on Cancer,' by Robert N. Proctor.
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  31.  1
    U. Deichmann & A. S. Travis (2010). Special Section: Darwinism and Scientific Practice in Historical Perspective: Guest Editors' Introduction. Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 41 (1):55-60.
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  32.  1
    U. Deichmann & A. S. Travis (2008). Philosophies in Biology: Introduction. History and Philosophy of the Life Sciences 30 (1):3-6.
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  33.  1
    Ute Deichmann (2006). The Kaiser's Chemist. [REVIEW] Times Literary Supplement 5385:6-7.
    Reviews the book "Between Genius and Genocide: The Tragedy of Fritz Haber, Father of Chemical Warfare," by Daniel Charles.
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  34.  1
    U. Deichmann (2000). An Unholy Alliance. The Nazis Showed That 'Politically Responsible' Science Risks Losing its Soul. Nature 405 (6788):739.
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  35.  1
    U. Deichmann (1994). Biology Under National Socialism: Archives in Germany and Poland. The Mendel Newsletter; Archival Resources for the History of Genetics and Allied Sciences (4):5-10.
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  36.  5
    Ulrich Charpa & Ute Deichmann (eds.) (2007). Jews and Sciences in German Contexts: Case Studies From the 19th and 20th Centuries. Mohr Siebeck.
    Problems, Phenomena, Explanatory Approaches Who is a German-Jewish Scientist? 1. The Einstein case and its paradoxes On 14 March 1929, Albert Einstein's ...
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  37. Ute Deichmann (2002). A Social Activist in Genetics. [REVIEW] Nature 420 (6914):363.
    Reviews the book 'Making Genes, Making Waves: A Social Activist in Science,' by Jon Beckwith.
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  38. Ute Deichmann (2002). Emigration, Isolation and the Slow Start of Molecular Biology in Germany. Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 33 (3):449-471.
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  39. Ute Deichmann, Michel Morange & Anthony S. Travis (2014). Editors’ Introduction to Special Issue. Perspectives in Biology and Medicine 57 (1):4-7.
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  40. Ute Deichmann (2010). Gemmules and Elements: On Darwin’s and Mendel’s Concepts and Methods in Heredity. Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 41 (1):85-112.
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  41. U. Deichmann, M. Morange & E. Davidson (2011). Introductory Comment on Six Papers From a Symposium on Experimental and Historical Aspects of Evolutionary Bioscience. Developmental Biology 357 (1):2.
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  42. Ute Deichmann (2014). Women and Genetics in Germany – Research and Careers Until 1950. In Rn, Eh & Mv (eds.), Elisabeth Schiemann 1881–1972 Vom AufBruch der Genetik und der Frauen in den UmBrüchen des 20. Basilisken-Presse 26-53.