Results for 'decisions with risk'

998 found
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  1. Reason, emotion and decision-making: risk and reward computation with feeling.Steven R. Quartz - 2009 - Trends in Cognitive Sciences 13 (5):209-215.
  2.  14
    IDEAS in AGORA: Decision-Making Risk: The Difference Between Risk And Uncertainity In Economic Activities.Gabriela Munteanu & Nicoleta Vasilcovschi - 2014 - Human and Social Studies 3 (2):34-46.
    Economic activities are always supposed to carry with them the risk of market. Our area of research is concerned with what is known as the model of risk decisions at the level of economic activity; a model that can be valuable at any point of economic development. In our research, we present important aspects of risk in taking decisions in the previous and current dynamics of the market. The conditions of taking decisions (...)
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  3. Ethical decision making in intensive care units: a burnout risk factor? Results from a multicentre study conducted with physicians and nurses.Carla Teixeira, Orquídea Ribeiro, António M. Fonseca & Ana Sofia Carvalho - 2014 - Journal of Medical Ethics 40 (2):97-103.
    Background Ethical decision making in intensive care is a demanding task. The need to proceed to ethical decision is considered to be a stress factor that may lead to burnout. The aim of this study is to explore the ethical problems that may increase burnout levels among physicians and nurses working in Portuguese intensive care units . A quantitative, multicentre, correlational study was conducted among 300 professionals.Results The most crucial ethical decisions made by professionals working in ICU were related (...)
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  4.  32
    On deciding to have a lobotomy: either lobotomies were justified or decisions under risk should not always seek to maximise expected utility.Rachel Cooper - 2014 - Medicine, Health Care and Philosophy 17 (1):143-154.
    In the 1940s and 1950s thousands of lobotomies were performed on people with mental disorders. These operations were known to be dangerous, but thought to offer great hope. Nowadays, the lobotomies of the 1940s and 1950s are widely condemned. The consensus is that the practitioners who employed them were, at best, misguided enthusiasts, or, at worst, evil. In this paper I employ standard decision theory to understand and assess shifts in the evaluation of lobotomy. Textbooks of medical decision making (...)
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  5.  51
    The hot hand belief and the gambler’s fallacy in investment decisions under risk.Jürgen Huber, Michael Kirchler & Thomas Stöckl - 2010 - Theory and Decision 68 (4):445-462.
    We conduct experiments to analyze investment behavior in decisions under risk. Subjects can bet on the outcomes of a series of coin tosses themselves, rely on randomized ‘experts’, or choose a risk-free alternative. We observe that subjects who rely on the randomized experts pick those who were successful in the past, showing behavior consistent with the hot hand belief. Obviously the term ‘expert’ suffices to attract some subjects. For those who decide on their own, we find (...)
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  6.  21
    Greater decision-making competence is associated with greater expected-value sensitivity, but not overall risk taking: an examination of concurrent validity.Andrew M. Parker & Joshua A. Weller - 2015 - Frontiers in Psychology 6:138740.
    Decision-making competence reflects individual differences in the susceptibility to decision-making errors, measured using tasks common from behavioral decision research (e.g., framing effects, under/overconfidence, following decision rules). Prior research demonstrates that those with higher decision-making competence report lower incidence of health-risking and antisocial behaviors, but there has been less focus on intermediate mechanisms that may impact real-world decisions, and, in particular, those implicated by normative models. Here we test the associations between measures of youth decision-making competence (Y-DMC) and one (...)
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  7.  90
    Double or nothing?! Small groups making decisions under risk in “Quiz Taxi”.Klemens Keldenich & Marcus Klemm - 2014 - Theory and Decision 77 (2):243-274.
    This paper investigates the behavior of contestants in the game show “Quiz Taxi” when faced with the decision whether to bet the winnings they have acquired on a final “double or nothing” question. The decision in this natural experiment is made by groups of two or three persons. This setup enables the decision-making process to be studied with regard to group and communication characteristics. The contestants show fairly risk averse behavior. There is also a significant heterogeneity in (...)
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  8.  19
    Decision making in HIV testing among a group with low HIV risk.Adrian Coyle, Maria Knapp & Edmond O'Dea - 1996 - Journal of Evaluation in Clinical Practice 2 (3):223-230.
  9.  79
    Impact of Induced Moods, Sensation Seeking, and Emotional Contagion on Economic Decisions Under Risk.Kirill Efimov, Ioannis Ntoumanis, Olga Kuskova, Dzerassa Kadieva, Ksenia Panidi, Vladimir Kosonogov, Nina Kazanina, Anna Shestakova, Vasily Klucharev & Iiro P. Jääskeläinen - 2022 - Frontiers in Psychology 12.
    In addition to probabilities of monetary gains and losses, personality traits, socio-economic factors, and specific contexts such as emotions and framing influence financial risk taking. Here, we investigated the effects of joyful, neutral, and sad mood states on participants’ risk-taking behaviour in a simple task with safe and risky options. We also analysed the effect of framing on risk taking. In different trials, a safe option was framed in terms of either financial gains or losses. Moreover, (...)
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  10.  8
    Simplified Risk-aware Decision Making with Belief-dependent Rewards in Partially Observable Domains.Andrey Zhitnikov & Vadim Indelman - 2022 - Artificial Intelligence 312 (C):103775.
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  11.  35
    Consistent inconsistencies? Evidence from decision under risk.Guillaume Hollard, Hela Maafi & Jean-Christophe Vergnaud - 2016 - Theory and Decision 80 (4):623-648.
    Conventional economic theory assumes that agents should be consistent across decisions. However, it is often observed that experimental subjects fail to report consistent preferences. So far, these inconsistencies are almost always examined singly. We thus wonder whether the more inconsistent individuals in one task are also more inconsistent in other tasks. We propose an experiment in which subjects are asked to report their preferences over risky bets so as to obtain, for each subject, three measures of inconsistencies: classical preference (...)
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  12.  22
    Risk‐Sensitive Assessment of Decision‐Making Capacity: A Comprehensive Defense.Scott Y. H. Kim & Noah C. Berens - 2023 - Hastings Center Report 53 (4):30-43.
    Should the assessment of decision‐making capacity (DMC) be risk sensitive, that is, should the threshold for DMC vary with risk? The debate over this question is now nearly five decades old. To many, the idea that DMC assessments should be risk sensitive is intuitive and commonsense. To others, the idea is paternalistic or incoherent, or both; they argue that the riskiness of a given decision should increase the epistemic scrutiny in the evaluation of DMC, not increase (...)
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  13. An experimental investigation of imprecision attitude and its relation with risk attitude and impatience.Michèle Cohen, Jean-Marc Tallon & Jean-Christophe Vergnaud - 2011 - Theory and Decision 71 (1):81-110.
    We report in this paper the result of three experiments on risk, ambiguity and time attitude. The first two differed by the population considered (students vs. general population) while the third one used a different protocol and concerned students and portfolio managers. We find quite a lot of heterogeneity at the individual level. Of principal interest was the elicitation of risk, time and ambiguity attitudes and the relationship among these (model free) measures. We find that on the student (...)
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  14. Risk Attitude in Decision Making: In Search of Trait-Like Constructs.Eldad Yechiam & Eyal Ert - 2011 - Topics in Cognitive Science 3 (1):166-186.
    We evaluate the consistency of different constructs affecting risk attitude in individuals’ decisions across different levels of risk. Specifically, we contrast views suggesting that risk attitude is a single primitive construct with those suggesting it consists of multiple latent components. Additionally, we evaluate such constructs as sensitivity to losses, diminishing sensitivity to increases in payoff, sensitivity to variance, and risk acceptance (the willingness to accept probable outcomes over certainty). In search of trait-like constructs, the (...)
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  15.  56
    Keep or trade? Effects of pay-off range on decisions with the two-envelopes problem.Raymond S. Nickerson, Susan F. Butler, Nathaniel Delaney-Busch & Michael Carlin - 2014 - Thinking and Reasoning 20 (4):472-499.
    The "two-envelopes" problem has stimulated much discussion on probabilistic reasoning, but relatively little experimentation. The problem specifies two identical envelopes, one of which contains twice as much money as the other. You are given one of the envelopes and the option of keeping it or trading for the other envelope. Variables of interest include the possible amounts of money involved, what is known about the process by which the amounts of money were assigned to the envelopes, and whether you are (...)
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  16.  21
    Decision-making competence predicts domain-specific risk attitudes.Joshua A. Weller, Andrea Ceschi & Caleb Randolph - 2015 - Frontiers in Psychology 6:139420.
    Decision Making Competence (DMC) reflects individual differences in rational responding across several classic behavioral decision-making tasks. Although it has been associated with real-world risk behavior, less is known about the degree to which DMC contributes to specific components of risk attitudes. Utilizing a psychological risk-return framework, we examined the associations between risk attitudes and DMC. Italian community residents (n = 804) completed an online DMC measure, using a subset of the original Adult-DMC battery (A-DMC; Bruine (...)
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  17. Dynamic Decision Making when Risk Perception Depends on Past Experience.Michèle Cohen, Johanna Etner & Meglena Jeleva - 2008 - Theory and Decision 64 (2-3):173-192.
    The aim of the paper is to propose a preferences representation model under risk where risk perception can be past experience dependent. A first step consists in considering a one period decision problem where individual preferences are no more defined only on decisions but on pairs (decision, past experience). The obtained criterion is used in the construction of a dynamic choice model under risk. The paper ends with an illustrative example concerning insurance demand. It appears (...)
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  18. The price for information about probabilities and its relation with risk and ambiguity.Giuseppe Attanasi & Aldo Montesano - 2012 - Theory and Decision 73 (1):125-160.
    In this article, ambiguity attitude is measured through the maximum price a decision maker is willing to pay to know the probability of an event. Two problems are examined in which the decision maker faces an act: in one case, buying information implies playing a lottery, while, in the other case, buying information gives also the option to avoid playing the lottery. In both decision settings, relying on the Choquet expected utility model, we study how the decision maker’s risk (...)
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  19.  82
    Risk and the value of information in irreversible decisions.Hans Gersbach - 1997 - Theory and Decision 42 (1):37-51.
    The analysis of the nexus between the value of information and risk is examined for sequential decisions with different degrees of future commitment, as e.g. environmental decisions. We find that in the linear case a riskier environment in general will increase the value of information. This result will be extended in the separable case to decreasing and increasing stochastic returns to scale. An example shows the ambiguity in the general case.
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  20.  11
    The Problem(s) with Representing Decision Processes under Uncertainty.Gilbert Skillman & Roberto Veneziani - 2023 - Journal of Post Keynesian Economics 46 (3):420-439.
    Underscoring the economic significance of the Knightian distinction between risk and uncertainty, Don Katzner forcefully challenges the continued dominance of the expected utility model based on subjective probability in macroeconomic analysis and offers in its place a simple yet elegant model of decision making inspired by the pioneering work of G.L.S. Shackle. In doing so, Katzner lends support to a research program to identify a more coherent and empirically grounded theory of decision making under uncertainty. Our paper makes three (...)
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  21.  3
    Decision-making about non-invasive prenatal testing: women’s moral reasoning in the absence of a risk of miscarriage in Germany.Stefan Reinsch, Anika König & Christoph Rehmann-Sutter - 2021 - New Genetics and Society 40 (2):199-215.
    This paper examines women’s experiences with decision-making about non-invasive prenatal testing (NIPT). Such tests offer knowledge about chromosomal disorders early in pregnancy, without the risk of miscarriage associated with invasive procedures such as amniocentesis. Based on qualitative interviews with women in Germany who used, or declined, NIPT, we show how some women, who would not consider amniocentesis due to the risk of miscarriage, welcome the knowledge provided by, and the additional agency resulting from, NIPT. For (...)
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  22.  10
    Ethical decision-making practices in SMEs: the role of risk acceptance and confidence level.Mohammad Rashed Hasan Polas, Mosab I. Tabash, Asghar Afshar Jahanshahi & Valentina Gomes Haensel Schmitt - 2022 - International Journal of Business Governance and Ethics 16 (4):437.
    The aim of this study is to examine the factors influencing ethical business decision-making on environmental issues, among employees of SMEs. To do so, a survey study was performed with 394 top managers of SMEs in the UAE using a questionnaire, and the data was statistically evaluated using SmartPLS 3.0. The results suggest that prior technology use has significant positive relationships with ethical decision-making and the level of risk acceptance. Furthermore, perceived competitive pressure has significant positive relationships (...)
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  23. Risk in a Simple Temporal Framework for Expected Utility Theory and for SKAT, the Stages of Knowledge Ahead Theory’, Risk and Decision Analysis, 2(1), 5-32. selten co-author.Robin Pope & Reinhard Selten - 2010/2011 - Risk and Decision Analysis 2 (1).
    The paper re-expresses arguments against the normative validity of expected utility theory in Robin Pope (1983, 1991a, 1991b, 1985, 1995, 2000, 2001, 2005, 2006, 2007). These concern the neglect of the evolving stages of knowledge ahead (stages of what the future will bring). Such evolution is fundamental to an experience of risk, yet not consistently incorporated even in axiomatised temporal versions of expected utility. Its neglect entails a disregard of emotional and financial effects on well-being before a particular (...) is resolved. These arguments are complemented with an analysis of the essential uniqueness property in the context of temporal and atemporal expected utility theory and a proof of the absence of a limit property natural in an axiomatised approach to temporal expected utility theory. Problems of the time structure of risk are investigated in a simple temporal framework restricted to a subclass of temporal lotteries in the sense of David Kreps and Evan Porteus (1978). This subclass is narrow but wide enough to discuss basic issues. It will be shown that there are serious objections against the modification of expected utility theory axiomatised by Kreps and Porteus (1978, 1979). By contrast the umbrella theory proffered by Pope that she has now termed SKAT, the Stages of Knowledge Ahead Theory, offers an epistemically consistent framework within which to construct particular models to deal with particular decision situations. A model by Caplin and Leahy (2001) will also be discussed and contrasted with the modelling within SKAT (Pope, Leopold and Leitner 2007). (shrink)
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  24.  12
    Risk aversion and rational choice theory do not adequately capture complexities of medical decision-making.Zeljka Buturovic - 2023 - Journal of Medical Ethics 49 (11):761-762.
    In his paper, ‘Patients, doctors and risk attitudes’, Makins argues that doctors, when choosing a treatment for their patient, need to follow their risk profile.1 He presents a pair of fictitious diseases facing a patient who either has ‘exemplitis’, which requires no treatment or ‘caseopathy’, which is severe and disabling and for which there is a treatment with unpleasant side effects. The doctor needs to decide whether the patient should pursue the unpleasant treatment, just in case he (...)
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  25.  37
    Pareto improvements by Pareto strategic voting under majority voting with risk loving and risk avoiding voters — A note.I. D. A. Macintyre - 1995 - Theory and Decision 39 (2):207-211.
    Voters satisfy maximin or maximax in their choices between sets of alternatives and secure a Pareto improvement by all voting strategically under simple majority voting for particular sincere preferences. Thus the assumption that strategic voting is a bad thing is challenged and the idea that we should reject voting because of the possibility of misrepresentation dismissed.
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  26. Understanding scientists' computational modeling decisions about climate risk management strategies using values-informed mental models.Lauren Mayer, Kathleen Loa, Bryan Cwik, Nancy Tuana, Klaus Keller, Chad Gonnerman, Andrew Parker & Robert Lempert - 2017 - Global Environmental Change 42:107-116.
    When developing computational models to analyze the tradeoffs between climate risk management strategies (i.e., mitigation, adaptation, or geoengineering), scientists make explicit and implicit decisions that are influenced by their beliefs, values and preferences. Model descriptions typically include only the explicit decisions and are silent on value judgments that may explain these decisions. Eliciting scientists’ mental models, a systematic approach to determining how they think about climate risk management, can help to gain a clearer understanding of (...)
     
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  27.  31
    Medical decision-making and communication of risks: an ethical perspective.C. Breitsameter - 2010 - Journal of Medical Ethics 36 (6):349-352.
    The medical decision-making process is currently in flux. Decisions are no longer made entirely at the physician's discretion: patients are becoming more and more involved in the process. There is a great deal of discussion about the ideal of ‘informed consent’, that is that diagnostic and therapeutic decisions should be made based on an interaction between physician and patient. This means that patients are informed about the advantages and disadvantages of a treatment as well as alternatives to the (...)
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  28.  20
    Democratic Decision Making and the Psychology of Risk.Andreas Christiansen & Bjørn Hallsson - 2017 - Les Ateliers de l'Éthique / the Ethics Forum 12 (1):51-83.
    Andreas Christiansen,Bjørn Hallsson | : In many cases, the public want to restrict an activity or technology that they believe to be dangerous, but that scientific experts believe to be safe. There is thus a tension between respecting the preferences of the people and making policy based on our best scientific knowledge. Deciding how to make policy in the light of this tension requires an understanding of why citizens sometimes disagree with the experts on what is risky and what (...)
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  29.  28
    Is risk regulation a strategic influence on decision making in the biotechnology industry?Joanna Chataway & Joyce Tait - 1993 - Agriculture and Human Values 10 (2):60-67.
    This paper discusses strategic decision making in firms pursuing biotechnology innovation and the influence of risk regulation on firm strategy. Data from three research projects, involving interviews with over 60 managers from agricultural and food related biotechnology companies and also over 60 key participants in the regulatory process in the UK and EC, shows a diversity of strategy and opinion. While some industry representatives identified new risk regulations governing the release of genetically manipulated organisms (GMOs) as the (...)
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  30.  3
    Decision-making under risk: when is utility-maximization equivalent to risk-minimization?Francesco Ruscitti, Ram Sewak Dubey & Giorgio Laguzzi - forthcoming - Theory and Decision:1-16.
    Motivated by the analysis of a general optimal portfolio selection problem, which encompasses as special cases an optimal consumption and an optimal debt-arrangement problem, we are concerned with the questions of how a personality trait like risk-perception can be formalized and whether the two objectives of utility-maximization and risk-minimization can be both achieved simultaneously. We address these questions by developing an axiomatic foundation of preferences for which utility-maximization is equivalent to minimizing a utility-based shortfall risk measure. (...)
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  31. Disclosure and rationality: Comparative risk information and decision-making about prevention.Peter H. Schwartz - 2009 - Theoretical Medicine and Bioethics 30 (3):199-213.
    With the growing focus on prevention in medicine, studies of how to describe risk have become increasing important. Recently, some researchers have argued against giving patients “comparative risk information,” such as data about whether their baseline risk of developing a particular disease is above or below average. The concern is that giving patients this information will interfere with their consideration of more relevant data, such as the specific chance of getting the disease (the “personal (...)”), the risk reduction the treatment provides, and any possible side effects. I explore this view and the theories of rationality that ground it, and I argue instead that comparative risk information can play a positive role in decision-making. The criticism of disclosing this sort of information to patients, I conclude, rests on a mistakenly narrow account of the goals of prevention and the nature of rational choice in medicine. (shrink)
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  32.  42
    Acceptable risks and burdens for children in research without direct benefit: a systematic analysis of the decisions made by the Dutch Central Committee.A. E. Westra, R. N. Sukhai, J. M. Wit, I. D. de Beaufort & A. F. Cohen - 2010 - Journal of Medical Ethics 36 (7):420-424.
    Objectives To evaluate whether the requirement of “minimal risk and burden” for paediatric research without direct benefit to the subjects compromises the ability to obtain data necessary for improving paediatric care. To provide evidence-based reflections on the EU recommendation that allows for a higher level of risk. Design and setting Systematic analysis of the approval/rejection decisions made by the Dutch Central Committee on Research involving Human Subjects (CCMO). Review methods The analysis included 165 proposals for paediatric research (...)
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  33.  26
    Approximate Number Processing Skills Contribute to Decision Making Under Objective Risk: Interactions With Executive Functions and Objective Numeracy.Silke M. Mueller & Matthias Brand - 2018 - Frontiers in Psychology 9:364873.
    Research on the cognitive abilities involved in decision making has shown that, under objective risk conditions (i.e., when explicit information about possible outcomes and risks is available), superior decisions are especially predicted by executive functions and exact number processing skills, also referred to as objective numeracy. So far, decision-making research has mainly focused on exact number processing skills, such as performing calculations or transformations of symbolic numbers. There is evidence that such exact numeric skills are based on approximate (...)
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  34.  38
    Democratic Decision Making and the Psychology of Risk.Christiansen Andreas & Hallsson Bjørn - 2017 - Les ateliers de l'éthique/The Ethics Forum 12 (1):51-83.
    Andreas Christiansen,Bjørn Hallsson | : In many cases, the public want to restrict an activity or technology that they believe to be dangerous, but that scientific experts believe to be safe. There is thus a tension between respecting the preferences of the people and making policy based on our best scientific knowledge. Deciding how to make policy in the light of this tension requires an understanding of why citizens sometimes disagree with the experts on what is risky and what (...)
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  35.  37
    Decision-theoretic and risk-based approaches to naked statistical evidence: some consequences and challenges.Rafal Urbaniak, Alicja Kowalewska, Pavel Janda & Patryk Dziurosz-Serafinowicz - 2020 - Law, Probability and Risk 19 (1):67-83.
    In the debate about the legal value of naked statistical evidence, Di Bello argues that (1) the likelihood ratio of such evidence is unknown, (2) the decision-theoretic considerations indicate that a conviction based on such evidence is unacceptable when expected utility maximization is combined with fairness constraints, and (3) the risk of mistaken conviction based on such evidence cannot be evaluated and is potentially too high. We argue that Di Bello’s argument for (1) works in a rather narrow (...)
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  36.  3
    Risk Control of Virtual Enterprise Based on Distributed Decision-Making Model.Zhaoying Ouyang - 2021 - Complexity 2021:1-11.
    Virtual enterprise is a dynamic alliance of businesses, in which multiple members undertake joint research, development, manufacturing, operation, etc. The complexity of the relationship between business members, coupled with many new technologies or methods applied in the alliance operation, leads to more uncertain factors and difficulties in the operation and risk management of the virtual enterprise. The distributed decision-making model is a fast and effective decision-making model, in which dispersed intellectual resources and information resources are dynamically integrated through (...)
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  37.  17
    Risk Assessment and Rational Decision Theory.Roger M. Cooke - 1982 - Dialectica 36 (4):329-351.
    SummaryI contend on both theoretical and historical grounds that quantitative risk assessment is relevant for policy determination only as a cost estimate. In particular, it provides a method for estimating the costs of a hypothetical insurance policy against the potential liabilities associated with a given course of action. It is not relevant to the question of rational choice under risk.RésuméJe montre, en partant d'arguments aussi bien théoriques qu'historiques, que le calcul quanti‐tatif des risques n'aide à la détermination (...)
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  38.  4
    Decisions: Risk and Reward.Johnnie E. V. Johnson & Alistair Bruce - 2008 - Routledge.
    In recent years leading figures in a variety of fields - political, financial, medical, and organizational - have become acutely aware of the need to effectively incorporate aspects of risk into their decision-making. This book addresses a wide range of contemporary issues in decision research, such as how individuals deal with uncertainty and complexity, gender-based differences in decision-making, what determines decision performance and why people choose risky activities. The book presents results from academic research carried out over the (...)
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  39.  23
    Discharge Decisions and the Dignity of Risk.Debjani Mukherjee - 2015 - Hastings Center Report 45 (3):7-8.
    Mrs. Smith's eyes filled with tears as she said, “I feel like I've done something wrong. Are they punishing me because I've been refusing therapy and won't go to a nursing home?” She acknowledged that she hadn't always listened to her doctors but said that she knew better now and wanted to go home and see if she could make it work. Many staff members at our rehabilitation hospital had explained their safety concerns to her, and some had enlisted (...)
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  40.  16
    Risk Theory: Rational Decision in the Face of Chance, Uncertainty, and Risk.Nicholas Rescher - 2021 - Springer Verlag.
    Apart from its foray into technical issues of risk assessment and management, this book has one principal aim. With situations of chancy outcomes certain key factors—including outcome possibilities, overall expectation, threat, and even luck—are measurable parameters. But risk is something different: it is not measurable a single parametric quantity, but a many-sided factor that has several different components, and constitutes a complex phenomenon that must be assessed judgmentally in a highly contextualized way. This book explains and analyzes (...)
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  41.  9
    Value Incommensurability: Ethics, Risk. And Decision-Making.Henrik Andersson & Anders Herlitz (eds.) - 2021 - New York, NY: Routledge.
    Incommensurability is the impossibility to determine how two options relate to each other in terms of conventional comparative relations. This book features new research on incommensurability from philosophers who have shaped the field into what it is today, including John Broome, Ruth Chang and Wlodek Rabinowicz. The book covers four aspects relating to incommensurability. In the first part, the contributors synthesize research on the competing views of how to best explain incommensurability. Part II illustrates how incommensurability can help us deal (...)
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  42.  7
    Risk, benefit, and social value in Covid-19 human challenge studies: pandemic decision making in historical context.Mabel Rosenheck - 2022 - Monash Bioethics Review 40 (2):188-213.
    AbstractDuring the Covid-19 pandemic, ethicists and researchers proposed human challenge studies as a way to speed development of a vaccine that could prevent disease and end the global public health crisis. The risks to healthy volunteers of being deliberately infected with a deadly and novel pathogen were not low, but the benefits could have been immense. This essay is a history of the three major efforts to set up a challenge model and run challenge studies in 2020 and 2021. (...)
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  43.  5
    Risk decision: The self-charity discrepancies in electrophysiological responses to outcome evaluation.Min Tan, Mei Li, Jin Li, Huie Li, Chang You, Guanfei Zhang & Yiping Zhong - 2022 - Frontiers in Human Neuroscience 16:965677.
    Previous studies have examined the outcome evaluation related to the self and other, and recent research has explored the outcome evaluation of the self and other with pro-social implications. However, the evaluation processing of outcomes in the group in need remains unclear. This study has examined the neural mechanisms of evaluative processing by gambling for the self and charity, respectively. At the behavioral level, when participants make decisions for themselves, they made riskier decisions following the gain than (...)
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  44.  18
    The influence of risk and monetary payment on the research participation decision making process.J. P. Bentley - 2004 - Journal of Medical Ethics 30 (3):293-298.
    Objectives: To determine the effects of risk and payment on subjects’ willingness to participate, and to examine how payment influences subjects’ potential behaviours and risk evaluations.Methods: A 3 × 3 , between subjects, completely randomised factorial design was used. Students enrolled at one of five US pharmacy schools read a recruitment notice and informed consent form for a hypothetical study, and completed a questionnaire. Risk level was manipulated using recruitment notices and informed consent documents from hypothetical biomedical (...)
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  45.  32
    Beyond informed choice: prenatal risk assessment, decision-making and trust.Nete Schwennesen, Mette Nordahl Svendsen & Lene Koch - 2010 - Clinical Ethics 5 (4):207-216.
    In 2004, prenatal risk assessment (PRA) was implemented as a routine offer in Denmark, in order to give all pregnant women an informed choice about whether to undergo prenatal testing. PRA is a non-invasive intervention performed in the first trimester of pregnancy and measures the risk of a fetus having Down's syndrome or other chromosomal disorders. The risk figure provides the basis for action, i.e. the decision about whether or not to undergo invasive fetal testing via the (...)
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  46.  4
    The Impact of Risk Preference in Decision Behavior on Urban Expansion Morphology.Zhangwei Lu, Lihua Xu, Yaqi Wu, Yijun Shi, Jinyang Deng & Xiaoqiang Shen - 2021 - Complexity 2021:1-15.
    With the rapid development of urbanization, the urban expansion morphology has been changing with complex driving mechanisms behind the urban evolution process. This article simulates the results of urban land development contingent upon decision-makers’ risk preferences and reveals the inherent law of the effect of risk preferences on urban expansion morphology. Results show that cautious decision-makers lead to the urban expansion morphology being relatively compact, and the reckless decision-makers lead the urban expansion to sprawl. Moreover, there (...)
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  47.  76
    IRB Decision-Making with Imperfect Knowledge: A Framework for Evidence-Based Research Ethics Review.Emily E. Anderson & James M. DuBois - 2012 - Journal of Law, Medicine and Ethics 40 (4):951-969.
    Institutional Review Board decisions hinge on the availability and interpretation of information. This is demonstrated by the following well-known historical example. In 2001, 24-year-old Ellen Roche died from respiratory distress and organ failure as a result of her participation in a study at Johns Hopkins Asthma and Allergy Center. The non-therapeutic physiological study, “Mechanisms of Deep Inspiration-Induced Airway Relaxation,” was designed to examine airway hyperresponsiveness in healthy individuals in order to better understand the pathophysiology of asthma. Participants inhaled hexamethonium, (...)
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  48.  3
    Risk Factors Associated With Quality of Life in Patients With Hepatitis B Virus Related Cirrhosis.Qi Zhang, Chunxiu Zhong, Shaohang Cai, Tao Yu, Xuwen Xu & Junhua Yin - 2022 - Frontiers in Psychology 12.
    Aim: To evaluate health-related quality of life of chronic hepatitis B and hepatitis B virus related cirrhosis patients and analyzed specific differences in all dimensions of HRQoL.Methods: A total of 349 patients met selection criteria were enrolled. The 36-Item Short-Form Health Survey was adopted.Results: Results showed that the physiological HRQoL of the cirrhotic group was significantly lower than that of the non-cirrhotic group, the psychological HRQoL was also lower. HRQoL was significantly negatively correlated with liver stiffness. We further evaluated (...)
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  49.  96
    Power Difference and Risk Perception: Mapping Vulnerability within the Decision Process of Pregnant Women towards Clinical Trial Participation in an Urban Middle‐Income Setting.C. den Hollander Geerte, lBrowne Joyce, Arhinful Daniel, Graaf Rieke & Klipstein-Grobusch Kerstin - 2016 - Developing World Bioethics:68-75.
    To address the burden of maternal morbidity and mortality in low‐ and middle‐income countries (LMICs), research with pregnant women in these settings is increasingly common. Pregnant women in LMIC‐context may experience vulnerability related to giving consent to participate in a clinical trial. To recognize possible layers of vulnerability this study aims to identify factors that influence the decision process towards clinical trial participation of pregnant women in an urban middle‐income setting. This qualitative research used participant observation, in‐depth interviews, and (...)
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  50.  33
    Dispositional anger and risk decision-making.Elisa Gambetti & Fiorella Giusberti - 2009 - Mind and Society 8 (1):7-20.
    In this study, we assessed the influence of trait anger on decisions in risky situations evaluating how it might interact with some contextual factors. One hundred and fifty-eight participants completed the Trait Anger scale of STAXI-2 and an inventory consisting of a battery of hypothetical everyday decision-making scenarios, representative of three specific domains: financial, social and health. Participants were also asked to evaluate familiarity and salience for each scenario. This study provides evidence for a relationship between individual differences (...)
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