The future of eugenics Nicolae Sfetcu March 8, 2019 Sfetcu, Nicolae, "The future of eugenics", SetThings (March 8, 2019), MultiMedia Publishing (ed.), URL = https://www.setthings.com/en/the-future-of-eugenics/ Email: nicolae@sfetcu.com This book is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International. To view a copy of this license, visit http://creativecommons.org/licenses/by-nd/4.0/. A partial translation of: Sfetcu, Nicolae, "Evoluția și etica eugeniei", SetThings (26 ianuarie 2018), MultiMedia Publishing (ed.), DOI: 10.13140/RG.2.2.27933.41449 URL = https://www.setthings.com/ro/ebooks/evolutia-si-etica-eugeniei/ The future of eugenics The potential use of genetic engineering has brought back past eugenics into bioethics disputes. There are opinions, such as those of Nicholas Agar, according to which non-coercive eugenics programs are inherently ethical. (Fletcher and Wertz 1990) Adherents of liberal eugenics argue that it is difficult to determine just what matters as an improvement (except for serious illness) and considers diversity to be important. For example, is it better for a child to be very smart? Some parents can choose a reasonable level of intelligence for the child, assuming they will have greater social opportunities in the latter case. (Agar 2004) In the case of genetic improvements, critics fear parents who can exaggerate certain traits, and suggest different limits on genetic intervention. (Sandel 2007) Parents' choices must not substantially diminish future choices for their children. (Agar 2004) The central moral principle of biomedical ethics involves an obligation ""to confer benefits and remove harms." (Beauchamp 1979, 135) Many theorists support the parents' ability to decide their children's genetics but contradict their obligation. In general, the idea is of a regulated system of the type considered by Robert Nozick, with controls to protect the well-being of future children and socially-valued goods (equal opportunities, elimination of discrimination). (Nozick 1974, 315)It goes on the assumption that the treatment of the disease can be mandatory, while genetic improvement is not. (Parens 1998) Buchanan et al. believes that parents should be required to choose a genetic treatment that promotes the health and wellbeing of the child but does not suggest that all potential parents would be required to seek advice on reproduction and to use in vitro fertilization. (Buchanan 2011) Such a requirement would be a violation of their procreative freedom. Critics fear that parents might obsessively focus on certain characteristics by exaggerating them. (Sandel 2007) For this reason, eugenics advocates propose limits on genetic intervention for improvement. Sara believes that variations could include, for example. (Sara 2014) • only improvements that will benefit future children regardless of the life plan they choose to pursue and do not strengthen the problematic social norms, (Agar 2004) or • only improvements that preserve the child's right to an open future, (Davis 2009) or • only improvements that keep open possibilities and protect some central nuclei of our human nature, (Glover 2008) or • only understandings that rational people will agree to be in the best interests of the child. (Green 2008) A "free-market" approach to the genetic development of children may result in a homogenising. Parents may be inclined to choose according to models accepted by society. In this case, improving technologies will "will grant racism and homophobia an unprecedented efficacy." (Agar 2004, 148) One concern about the obligation to produce the best child in a particular society is that social norms may be discriminatory, so that in the end, for example, most children will be boys, extremists and heterosexuals. (Sparrow 2011) Jonathan Anomaly believes that the current demography of developed countries is worrying because people with a higher IQ, higher education and higher income, reproduce at relatively low levels because they have many other activities, they consider priority, including creative activities, volunteering, entertainment and career. (Anomaly 2017) The widespread acceptance of abortion as a eugenic practice suggests that there may be little resistance to more sophisticated methods of eugenic selection. More and more, prenatal diagnosis of genetic disorders is performed based on molecular tests for mental disorders. (Leroi 2006) The geneticists highlight that comparative genomic hybridization (CGH) microarrays could be used to examine a single embryo or fetus for thousands of mutations. (Van den Veyver and Beaudet 2006) These matrices, which are based on bacterial artificial chromosome, can detect deletions and duplications of aneurysms. An impediment to a total prenatal universal screening for all known mutations is the invasive nature of the procedure it requires amniocentesis or chorionic sampling to recover cells from the amniotic sac, and the traumatic nature of the treatment. It is possible that in the future a total mutation screening will not be used in prenatal diagnosis, but rather in pre-implantation genetic diagnosis (PGD). As with prenatal diagnosis, PGD is generally performed only when a family medical history suggests that the embryo is at risk of a specific disease. (Braude et al. 2002) The procedure has spread rapidly, although it remains illegal in some countries. Is it possible that one day, every citizen of an industrialized nation has survived, as an embryo, a PGD screen? Most do not think it is possible, as it is too expensive, inconvenient and limited. (Silver 2000) Nature invented an inexpensive, easy and pleasant way to conceive a child. Some specialists, including Francis Crick, have suggested paying people not to reproduce or to establish a parental licensing scheme. (Crick 1963) There are reasons to support these policies. Such a policy would be effective only in the ideal case where there would be no corruption, bureaucracy, or black markets for pregnancy. The human genome initiative was a fifteen-year study aimed at mapping and sequencing genes that constitute the human genome. Mapping determines the localization of genes on chromosomes, while sequencing identifies the parts of the gene. The initiative is geared towards the entire human genome, and so it will also provide information that would be vital for both positive and negative eugenic programs. (Fletcher and Wertz 1990) The sequencing of the human genome can help us in human evolution. The human genome project can help us understand diseases for direct appropriate treatment, identify mutations that cause disease, and correct them. The human genome project has made it possible to effectively modify the human species. Scientists such as Richard Lynn, Raymond Cattell and Gregory Stock have been calling for open eugenics policies using modern technology. (Lynn 2001) A "sperm bank of geniuses" was set up by Robert Klark Graham, of which nearly 230 children were conceived (the best-known donors were Nobel Prize winners William Shockley and J.D. Watson). In 1999, the sperm bank was closed, two years after Graham's death. The project has generated many ethical, legal and social concerns regarding possible discrimination. Also, some authors have highlighted the need to address the possible social consequences of mapping the human genome. (Lock, Young, and Cambrosio 2000) Paul Freund and Laurence Tribe claimed that the unborn have the right to random genomes. ""The mystery of individual personality, resting on the chance combination of ancestral traits, is the basis of our sense of mutual compassion and at the same time, of accountability." (Freund 1972) Bibliograhy Agar, Nicholas. 2004. Liberal Eugenics: In Defence of Human Enhancement. 1 edition. Malden, MA: Wiley-Blackwell. Anomaly, Jonathan. 2017. "Defending Eugenics." SSRN Scholarly Paper ID 2848702. Rochester, NY: Social Science Research Network. https://papers.ssrn.com/abstract=2848702. Beauchamp, Tom L. 1979. "Principles of Biomedical Ethics Paperback Oxford University Press." 1979. https://global.oup.com/ushe/product/principles-of-biomedical-ethics9780199924585?cc=ro&lang=en&. Braude, Peter, Susan Pickering, Frances Flinter, and Caroline Mackie Ogilvie. 2002. "Preimplantation Genetic Diagnosis." Nature Reviews. Genetics 3 (12): 941–53. https://doi.org/10.1038/nrg953. Buchanan, Allen. 2011. Better than Human: The Promise and Perils of Enhancing Ourselves. Oxford University Press. Crick, Francis. 1963. "Eugenics and Genetics." In Man and His Future; a Ciba Foundation Volume., [1st American ed.]. Boston,: Little, Brown,. https://www.biodiversitylibrary.org/bibliography/35884. Davis, Dena. 2009. Genetic Dilemmas: Reproductive Technology, Parental Choices, and Children's Futures. Oxford, New York: Oxford University Press. Fletcher, John C., and Dorothy C. Wertz. 1990. "Ethics, Law, and Medical Genetics: After the Human Genome Is Mapped." Emory Law Journal 39 (3): 747–809. Freund, Paul A. 1972. "Can Man Control His Biological Evolution? A Symposium on Genetic Engineering. Xeroxing Human Beings." Bulletin of the Atomic Scientists. Glover, Jonathan. 2008. Choosing Children: Genes, Disability, and Design. Uehiro Series in Practical Ethics. Oxford, New York: Oxford University Press. Green, Ronald M. 2008. Babies by Design. https://books.google.com/books/about/Babies_by_Design.html?id=-Rvjimmw_AcC. Lock, Margaret, Allan Young, and Alberto Cambrosio, eds. 2000. Living and Working with the New Medical Technologies: Intersections of Inquiry. Cambridge, UK ; New York, NY, USA: Cambridge University Press. Lynn, Richard. 2001. Eugenics: A Reassessment. Greenwood Publishing Group. Nozick, Robert. 1974. Anarchy, State, and Utopia. Basic Books. Parens, Erik. 1998. Is Better Always Good?: The Enhancement Project. Hastings Center. Sandel, Michael J. 2007. "The Case against Perfection - Michael J. Sandel | Harvard University Press." 2007. http://www.hup.harvard.edu/catalog.php?isbn=9780674036383. Sara, Goering. 2014. "Eugenics," July. https://plato.stanford.edu/archives/fall2014/entries/eugenics/. Silver, L. M. 2000. "Reprogenetics: Third Millennium Speculation. The Consequences for Humanity When Reproductive Biology and Genetics Are Combined." EMBO Reports 1 (5): 375–78. https://doi.org/10.1093/embo-reports/kvd096. Sparrow, Robert. 2011. "Liberalism and Eugenics." Australasian Journal of Philosophy 89 (3): 499–517. Van den Veyver, Ignatia B., and Arthur L. Beaudet. 2006. "Comparative Genomic Hybridization and Prenatal Diagnosis." Current Opinion in Obstetrics & Gynecology 18 (2): 185–91. https://doi.org/10.1097/01.gco.0000192986.22718.cc.