A number of recent studies have examined the effects of phonological variation on the perception of speech. These studies show that both the lexical representations of words and the mechanisms of lexical access are organized so that natural, systematic variation is tolerated by the perceptual system, while a general intolerance of random deviation is maintained. Lexical abstraction distinguishes between phonetic features that form the invariant core of a word and those that are susceptible to variation. Phonological inference relies on the (...) context of surface changes to retrieve the underlying phonological form. In this article we present a model of these processes in speech perception, based on connectionist learning techniques. A simple recurrent network was trained on the mapping from the variant surface form of speech to the underlying form. Once trained, the network exhibited features of both abstraction and inference in its processing of normal speech, and predicted that similar behavior will be found in the perception of nonsense words. This prediction was confirmed in subsequent research (Gaskell & Marslen-Wilson, 1994). (shrink)

Most words in English are ambiguous between different interpretations; words can mean different things in different contexts. We investigate the implications of different types of semantic ambiguity for connectionist models of word recognition. We present a model in which there is competition to activate distributed semantic representations. The model performs well on the task of retrieving the different meanings of ambiguous words, and is able to simulate data reported by Rodd, Gaskell, and Marslen‐Wilson [J. Mem. Lang. 46 (2002) 245] (...) on how semantic ambiguity affects lexical decision performance. In particular, the network shows a disadvantage forwords with multiple unrelated meanings (e.g., bark) that coexists with a benefit for words with multiple related word senses (e.g., twist). The ambiguity disadvantage arises because of interference between the different meanings, while the sense benefit arises because of differences in the structure of the attractor basins formed during learning. Words with few senses develop deep, narrow attractor basins, while words with many senses develop shallow, broad basins. We conclude that the mental representations of word meanings can be modelled as stable states within a high‐dimensional semantic space, and that variations in the meanings of words shape the landscape of this space. (shrink)

I respond to Norris et al.'s criticism of Gaskell and Marslen- Wilson (1997). When the latter's network is tested in circumstances comparable to the Merge simulations in the target article, it produces the desired pattern of results. In another area of potential feedback in spoken word processing, aspects of lexical content influence word recognition and our network provides a simple explanation of why such effects emerge. It is unclear how such effects would be accommodated by Merge.

Learning a mapping involves finding regularities in a training set and generalization to novel patterns. Clark & Thornton's type distinction has been discussed in terms of generalization, but has limited value in this respect. However, in terms of detection of regularities in the training set, the distinction is more valid, as it provides a measure of complexity and correlates with the size of search space.

With contributions from the fields of psychology, linguistics, cognitive neuroscience, attention, genetics, development, and neuropsychology divided into five themed sections, this new edition of The Oxford Handbook of Psycholinguistics is unparalleled in its breadth of coverage.

We address the notion of integration of new memory representations and the potential dependence of this phenomenon on sleep, in light of recent findings on the lexicalization of spoken words. A distinction is introduced between measures tapping directly into the strength of the newly acquired knowledge and indirect measures assessing the influence of this knowledge on spoken word identification.

Background and aims: Recent investigations have highlighted the value of neuropsychological testing for the assessment and screening of Alcohol-Related Brain Damage. The aim of the present study was to evaluate the suitability of the Addenbrooke’s Cognitive Examination and the Repeatable Battery for the Assessment of Neuropsychological Status for this purpose. Methods: Comparing 28 participants with ARBD and 30 alcohol-dependent participants without ARBD we calculated Area Under the Curve statistics, sensitivity and specificity values, base-rate adjusted predictive values, and likelihood ratios for (...) both tests. Results: High levels of screening accuracy were found for the total scores of both the ACE-III and RBANS at multiple cut-off points. Removing participants with a history of polysubstance from the samples improved the diagnostic capabilities of the RBANS substantially, while only minor improvements to the ACE-III’s accuracy were observed. Conclusions: Overall, both the ACE-III and RBANS are suitable tools for ARBD screening within an alcohol-dependent population, though the RBANS is the superior of the two. Clinicians using these tools for ARBD screening should be cautious of false-positive outcomes and should therefore combine them with other assessment methods and more detailed neuropsychological testing before reaching diagnostic decisions. (shrink)

The Oxford Handbook of Psycholinguistics brings together the views of 75 leading researchers in psycholinguistics to provide a comprehensive and authoritative review of the current state of the art in psycholinguistics. With almost 50 chapters written by experts in the field, the range and depth of coverage is unequalled.

Neurons of organisms with complex and flexible behavior, especially humans, must precisely control protein localization and activity to support higher brain functions such as learning and memory. In contrast, simpler organisms generally have simpler individual neurons, less complex nervous systems and display more limited behaviors. Strikingly, however, many key neuronal proteins are conserved between organisms that have very different degrees of behavioral complexity. Here we discuss a possible mechanism by which conserved neuronal proteins acquired new attributes that were crucial in (...) the evolution of complexity of nervous system structure and function. Specifically, we hypothesize that vertebrate‐specific post‐translational palmitoylation sites and PDZ‐binding protein‐protein interaction motifs act as gain‐of‐function mutations, increasing the regulatory potential of conserved proteins without affecting their core functions. We further hypothesize that the additional regulation of neurotransmitter receptors and other membrane proteins made possible by these sites and motifs is critical for the function of complex nervous systems. (shrink)

As John Rist presents Augustine, he was a man who “lived on the frontier between the ancient world and mediaeval Western Europe”. Among the the many who tried to transform ancient thought, Rist tells us, Augustine was “the most radical and the most influential”.

Recent magnetic resonance imaging and pathological studies have indicated that axonal loss is a major contributor to disease progression in multiple sclerosis. 1 H magnetic resonance spectroscopy, through measurement of N -acetyl aspartate, a neuronal marker, provides a unique tool to investigate this. Patients with primary progressive multiple sclerosis have few lesions on conventional MRI, suggesting that changes in normal appearing white matter, such as axonal loss, may be particularly relevant to disease progression in this group. To test this hypothesis (...) NAWM was studied with MRS, measuring the concentration of N -acetyl derived groups. Single-voxel MRS using a water-suppressed PRESS sequence was carried out in 24 patients with primary progressive multiple sclerosis and in 16 age-matched controls. Ratios of metabolite to creatine concentration were calculated in all subjects, and absolute concentrations were measured in 18 patients and all controls. NA/Cr was significantly lower in NAWM in patients than in controls, as was the absolute concentration of NA. There was no significant difference in the absolute concentration of creatine between the groups. This study supports the hypothesis that axonal loss occurs in NAWM in primary progressive multiple sclerosis and may well be a mechanism for disease progression in this group. (shrink)

This collection of essays examines how philosophers in the Western tradition have viewed and written about children through the ages. (Philosophy).

Lucius Annaeus Seneca was a Roman Stoic philosopher, dramatist, statesman, and advisor to the emperor Nero, all during the Silver Age of Latin literature. The Complete Works of Lucius Annaeus Seneca is a fresh and compelling series of new English-language translations of his works in eight accessible volumes. Edited by world-renowned classicists Elizabeth Asmis, Shadi Bartsch, and Martha C. Nussbaum, this engaging collection helps restore Seneca—whose works have been highly praised by modern authors from Desiderius Erasmus to Ralph Waldo Emerson—to (...) his rightful place among the classical writers most widely studied in the humanities. _Hardship and Happiness_ collects a range of essays intended to instruct, from consolations—works that offer comfort to someone who has suffered a personal loss—to pieces on how to achieve happiness or tranquility in the face of a difficult world. Expertly translated, the essays will be read and used by undergraduate philosophy students and experienced scholars alike. (shrink)

In this chapter we outline the need to develop ethical frameworks to guide research on the role of animal-orientated health, therapeutic, and service interventions. We discuss findings from our research on uses of animals in therapeutic settings and benefits of human–canine interactions for human health. These stories from the field reveal that current ethics review processes do not recognise the animal as an equal partner in the potential reciprocal benefits and risks of therapeutic human–animal relationships. We explore how these review (...) processes frame research on the relationships between humans and non-human animals and use the ethical review system of Aotearoa/New Zealand as an example. We propose an ethical framework that goes beyond animal welfare legislation and recognises a range of non-human animal capacities. (shrink)

Extensive research has demonstrated that rs1360780, a common single nucleotide polymorphism within the FKBP5 gene, interacts with early-life stress in predicting psychopathology. Previous results suggest that carriers of the TT genotype of rs1360780 who were exposed to child abuse show differences in structure and functional activation of emotion-processing brain areas belonging to the salience network. Extending these findings on intermediate phenotypes of psychopathology, we examined if the interaction between rs1360780 and child abuse predicts resting-state functional connectivity (rsFC) between the amygdala (...) and other areas of the salience network. We analyzed data of young European adults from the general population (N = 774; mean age = 18.76 years) who took part in the IMAGEN study. In the absence of main effects of genotype and abuse, a significant interaction effect was observed for rsFC between the right centromedial amygdala and right posterior insula (p <.025, FWE-corrected), which was driven by stronger rsFC in TT allele carriers with a history of abuse. Our results suggest that the TT genotype of rs1360780 may render individuals with a history of abuse more vulnerable to functional changes in communication between brain areas processing emotions and bodily sensations, which could underlie or increase the risk for psychopathology. (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

We show that a complete first-order theory T is distal provided it has a model M such that the theory of the Shelah expansion of M is distal.

In “Understanding Demonstratives”, Gareth Evans bites the bullet regarding Rip van Winkle cases in cognitive dynamics: the fact that Rip sleeps for twenty years and completely loses track of time means he is unable to retain his original belief that “Today is a fine day”. In this paper, the author argues that Evans need not bite this bullet because there are resources in his account of the cognitive dynamics involved in belief retention developed in The Varieties of Reference to (...) successfully confront the challenge posed by the Rip van Winkle case. In particular, when we combine the two central elements of Evans’s cognitive dynamics – the skill of keeping track of one’s spatio-temporal location in addition to memory – it is possible to arrive at the conclusion that it is indeed possible for Rip to retain and re-express his original belief. (shrink)

Gareth Evans' proposal, as amended by Steven Neale –that a definite pronoun with a quantifiedantecedent that does not bind it has the sense ofa definite description – has been challenged inthe singular case by appeal to counter-examplesinvolving failure of the uniqueness condition forthe legitimacy of a singular description. Thischallenge is here extended to the plural.Counter-examples are provided by cases in which aplural description `the Fs' does not denote,despite the propriety of the use of `they' or`them' it is to replace, (...) because of failure ofcumulativeness. A noncumulative predicate isnot distributive, and conditions for thelegitimacy of `the Fs' designed to accommodatenondistributive `Fs' are given in the context ofa two sorted theory with generalized quantifiers.Failure of cumulativeness is not to be confusedwith failure of maximality as Neale and othersdefine it. If not all Fs are Gs, `The Fs are Gs'is false; but it does not follow that `the Fs' isillegitimate; and if `Fs' is distributive. it isso only if there are no Fs. These differencesgranted, I give a partial defense of theEvans–Neale proposal from deficiencies in analternative based on the views of P. T.Geach. (shrink)

Gareth Evans'' proposal, as amended by Steven Neale –that a definite pronoun with a quantifiedantecedent that does not bind it has the sense ofa definite description – has been challenged inthe singular case by appeal to counter-examplesinvolving failure of the uniqueness condition forthe legitimacy of a singular description. Thischallenge is here extended to the plural.Counter-examples are provided by cases in which aplural description `the Fs'' does not denote,despite the propriety of the use of `they'' or`them'' it is to replace, (...) because of failure ofcumulativeness. A noncumulative predicate isnot distributive, and conditions for thelegitimacy of `the Fs'' designed to accommodatenondistributive `Fs'' are given in the context ofa two sorted theory with generalized quantifiers.Failure of cumulativeness is not to be confusedwith failure of maximality as Neale and othersdefine it. If not all Fs are Gs, `The Fs are Gs''is false; but it does not follow that `the Fs'' isillegitimate; and if `Fs'' is distributive. it isso only if there are no Fs. These differencesgranted, I give a partial defense of theEvans–Neale proposal from deficiencies in analternative based on the views of P. T.Geach. (shrink)

In The Paradox of Self-Consciousness, Jose Luis Bermúdez presents an abductive argument for what he calls ‘the Symmetry Thesis’ about self-ascription: in order to have the ability to self-ascribe psychological predicates to oneself, one must be able to ascribe psychological predicates to other subjects like oneself. Bermúdez discusses joint engagement as a key phenomenon that underwrites his abductive argument for the Symmetry Thesis. He argues that the ability to self-ascribe is “constituted” by the intersubjective relations that are realized in joint (...) engagement. I will argue in §1 that although Bermúdez may be correct that these phenomena support the idea that pre-linguistic infants and non-linguistic animals possess primitive forms of self-consciousness, for conceptual reasons, his account of joint engagement cannot be used to argue for the Symmetry thesis. I will argue in §2 that while Bermúdez is correct that joint engagement is significant for the constitution of self-ascription, his description of that phenomenon is too robust, because it requires that the infant have a mental representation of the other as a psychological subject of perceptions. I argue that Bermúdez’s description requires an iteration of representations each of which requires a form of self-reference, which goes against Bermudez’s aim of avoiding the paradox of self-consciousness. In presenting his argument for the Symmetry thesis and his account of joint engagement, Bermúdez critiques P. F. Strawson’s argument for the Symmetry Thesis. In §3 of the paper, I turn to the positive project of presenting a constructive argument for the Symmetry thesis. In a variety of sources, P. F. Strawson and Gareth Evans present a transcendental argument for the Symmetry thesis. I suggest that an argument for the Symmetry thesis is available in Strawson’s notion of the primitiveness of the person. In §4, this leads to a corresponding account of joint engagement. Instead of the robust account of joint engagement presented by Bermúdez, I suggest that the infant perceives the mother’s acknowledgement of the infant without the capacity for self-reference that the Bermúdez’s iteration requires. I reconstruct an account of other-ascription in terms of what I call “person perception,” relying on a recent discussion of Strawson’s view by Axel Seemann (2008). On the Strawsonian account that I provide, an adult summons a child to recognize and acknowledge a form of life in which it participates as a person. In closing, I consider how my account of other-ascription differs from two classic accounts— the theory-theory and the simulation theory— and discuss how my account provides a genuine third alternative: the Persons theory. I would argue that the Persons theory offers a new approach to key issues in philosophy and psychology concerning self-consciousness and intersubjectivity. (shrink)

ISSUES IN THE PHILOSOPHY OF LANGUAGE edited by Alfred M. MacKay and Daniel D. Merrill. (Oberlin Colloquium, 1972.) Yale U.P., 1976. xiv+161 pp. £7.50.TRUTH AND MEANING: Essays in Semantics, edited by Gareth Evans and John McDowell. Clarendon Press: O.U.P., 1976. xxiii+420 pp. £11.50.

This paper outlines three broad ways one might think about logical correctness: the Realist approach, the One-Language approach and my own Neo-Carnapian view. Although the realist and one-language views have dominated the philosophy of logic in recent years, I argue against them, favouring of the Neo-Carnapian approach.

We tend to associate Henry David Thoreau with the renunciation of material possessions, projecting onto him our fantasies of a life lived beyond the modern obsession with "things." But Thoreau's practical philosophy held a special place for tools, artworks, Native American artifacts, and a variety of natural phenomena. In Mindprints, Ivan Gaskell focuses on the material items that were important to Thoreau, using them to reveal Thoreau's unique and profound aesthetics of everyday life and the environment. "Mindprint" was Thoreau's (...) term for a material object that has captured the presence of its maker and first user. Thoreau applied the term to ancient stone artifacts and other objects in an effort to capture something of the relationship between material items and humans. For Thoreau, these relationships contribute to the creation of "worlds." By looking at Thoreau's engagement with material worlds through his writings and his practical philosophical experiment at Walden Pond--but also, importantly, via his work as a designer of improved pencils, as a house builder, as a land surveyor, and as a collector--Gaskell reveals the aesthetics at the heart of Thoreau's thinking. (shrink)

The essential overview of the key philosophical ideas and controversies that have shaped the world of science.