This paper integrates genetical studies of variation in the wing patterns of Lepidoptera with experimental investigations of developmental mechanisms. Research on the tropical butterfly,Bicyclus anynana, is described. This work includes artificial selection of lines with different patterns of wing eyespots followed by grafting experiments on the lines to examine the phenotypic and genetic differences in terms of developmental mechanisms. The results are used to show how constraints on the evolution of this wing pattern may be related to the developmental organisation. (...) The eyespot pattrn can be envisaged as a set of developmental homologues; a common developmental mechanism is associated with a quantitative genetic system involving high genetic correlations. However, individual genes which influence only subsets of the eyespots, thus uncoupling the interdependence of the eyespots, may be important in evolutionary change. The postulated evolutionary constraints are illustrated with respect to differences in wing pattern found among other species ofBicyclus. (shrink)

In this paper we describe a test for Nijhout's hypothesis that the eyespot patterns on butterfly wings are the result of a threshold reaction of the epidermal cells to a concentration gradient of a diffusing degradable morphogen produced by focal cells at the centre of the future eyespot. The wings of the nymphalid butterfly, Bicyclus anynana, have a series of eyespots, each composed of a white pupil, a black disc and a gold outer ring. In earlier extirpation and transplantation experiments (...) it has been established that these eyespots are indeed organised around groups of signalling cells active during the first hours of pupal development. If these cells were to supply the positional information for eyespot formation in accordance with Nijhout's diffusion-degradation gradient model, then, when two foci are close together, the signals should sum, and this effect should be apparent in the detailed shape of the resulting pigment pattern. We give an equation for the form of the contours that would be obtained in this manner. We use this to test the morphogen gradient hypothesis on measurements of the outlines of fused eyespots obtained either by grafting focal cells close together, or by using a mutation that produces adjacent fused eyespots. The contours of the fused patterns were found to satisfy our equation, thus corroborating Nijhout's hypothesis to the extent possible with this particular type of experiment. (shrink)

The ‘Pascalian’ tradition in French thought is a moral rigorism that demands practical embodiment while denying that any embodiment of its demands can ever be complete. The power of this tradition may be seen even in French political moralists of the 20th century. It is revealed in Bergson’s view that the open morality must seek practical expression through the closed society, while constantly subverting it. It is revealed in Levinas’s claim that the ‘saying’ requires to be ‘said’ but (...) always undermines the said, so that what is explicit is ‘always wanting’. Directly, and also through the influence of Levinas, the Pascalian tradition exerts a complex influence on Derrida, in whose thoughts about the topic of justice moral rigorism transforms into an idea of radical epistemic incompleteness, or infinite deferral. ‘Pascalians’ such as Bergson, Levinas and Derrida are convinced, consequently, that the ethical can be given only sporadic or uninstitutionalized political expression; in this regard, they may be contrasted with ‘Lockeans’ who believe that political theory is at one remove from our deepest ethical or religious conclusions. In light of that contrast, the differences between Continental and Anglophone political theory may be traced to post-Reformation circumstances rather than, as is often supposed, to the Enlightenment. (shrink)

With this important volume, Karen Houle and Jim Vernon have done a masterful job at assembling a collection of essays on a topic which, until recently, has gone undeservedly neglected in contemporary scholarship—the relationship between German Idealist, G. W. F. Hegel, and twentieth Century French philosopher, Gilles Deleuze. The relationship between these two thinkers has been neglected in favor of Deleuze’s relationship to other historical figures , and Hegel’s relationship to other contemporary figures . In this context, the (...) present volume not only impressively represents some of the best scholarship on the relationship between German Idealism and contemporary French philosophy, but also has now come to form a substantial portion of research on the topic of the relationship between Hegel and Deleuze, in particular. A notable exception to this neglect is the recent book by Henry Somers-Hall, Hegel, Deleuze, and the Critique of Representati .. (shrink)

The principal findings of experimental economics are that impersonal exchange in markets converges in repeated interaction to the equilibrium states implied by economic theory, under information conditions far weaker than specified in the theory. In personal, social, and economic exchange, as studied in two-person games, cooperation exceeds the prediction of traditional game theory. This book relates these two findings to field studies and applications and integrates them with the main themes of the Scottish Enlightenment and with the thoughts of F. (...) A. Hayek. (shrink)

Mark Vernon links the resources of the philosophical tradition with numerous illustrations from modern culture to ask what friendship is and how it relates to sex, work, politics and spirituality. Unusually, he argues that Plato and Nietzsche, as much as Aristotle and Aelred, should be put center stage. Their penetrating and occasionally tough insights are invaluable if friendship is to be a full, not merely sentimental, way of life for today.

Are culture driven ethical conflicts apparent in the discourse of the protagonists? A multi-year, multi-cultural study of managers by Trompenaars and Hampden-Turner resulted in two conclusions relevant to business ethics. The first is that intercultural business conflicts can often be traced to a finite set of cultural differences. The second is that enough similarities exist between cultures to provide the grounds for conflict resolution. The research reported here gives credence to their study when applied to an ethical conflict viewed from (...) French and American perspectives. (shrink)

Against associative obligations -- Particularizing obligation : the normative role of risk -- The social waiver -- Compatriot preference and the iteration proviso -- Humanitarian intervention and the case for natural duty -- Associative risk and international crime -- A global harm principle? -- Citizens in the world.

Professor Vernon L. Smith is a major creator of the new discipline of experimental economics. This collection of his papers from 1962 to 1990 surveys key developments in the field from early attempts to study economic behaviour in now classic double oral auction markets through recent studies of industrial organization and decision making. Topics covered include monopoly and oligopoly, supply and demand theory under posted pricing, uniform pricing, double continuous auction, and sealed bid-offer auctions; hypothetical valuation and market pricing; (...) asset price bubbles; predatory pricing; market contestability and natural monopoly; and the methodology of experimental economics. Taken together, the papers form a history of the study of economics under controlled conditions. (shrink)

Science and Homosexualities is the first anthology by historians of science to examine European and American scientific research on sexual orientation since the coining of the word "homosexual" almost 150 years ago. This collection is particularly timely given the enormous scientific and popular interest in biological studies of homosexuality, and the importance given such studies in current legal, legislative and cultural debates concerning gay civil rights. However, scientific and popular literature discussing the biology of sexual orientation have been short-sighted in (...) representing it as objective, new scientific work. This volume demonstrates that the quest for the biological "cause" of homosexuality and other sexualities is as old as the term itself. These essays explore the active role experimental subjects played in shaping scientific theories of homosexuality and cultural perceptions of sexuality and sexual identity. Finally this anthology studies the way in which this doctor-patient interaction shaped not only scientific theories of homosexuality, but also cultural perceptions and self-identities as well. Contributors include: Garland E. Allen, Erin G. Carlston, Julian Carter, Alice D. Dreger, Anne Fausto-Sterling, Margaret Gibson, Stephanie Kenen, Hubert Kennedy, Harry Oosterhuis, James Steakley, Richard Pillard, Jennifer Terry. (shrink)

This article claims that it is not mutual benefit but mutual risk that grounds compatriot preference. Exposure to risks such as state abuse provide us with a reason to take our compatriots' interests seriously. The same argument, however, displays the limits of this reasoning, and also grounds a demanding obligation to aid other societies.

The book also points to some of the ways in which polities currently termed 'liberal democracies' fall clearly short of the values that might legitimize them.

Steven French articulates and defends the bold claim that there are no objects in the world. He draws on metaphysics and philosophy of science to argue for structural realism--the position that we live in a world of structures--and defends a form of eliminativism about objects that sets laws and symmetry principles at the heart of ontology.

I. On the morning of 28 November 1979 flight TE-901, a DC-10 operated by Air New Zealand Limited, took off from Auckland, New Zealand, on a sightseeing passenger flight over a portion of Antarctica. The pilot in command was Captain Collins. The following are paragraphs from the official Report of the Royal Commission that inquired into the events surrounding that flight.

The politics of wellbeing and the new science of happiness have shot up the agenda since Martin Seligman coined the phrase "positive psychology". After all, who does not want to live the good life? So ten years on, why is it that much of this otherwise welcome debate sounds like as much apple-pie - "work less", "earn enough", "keep fit", "find meaning", "enjoy freedoms"? The reason is not, ultimately, cynicism. Rather, it is because a central, tricky question is being glossed (...) over: just what is wellbeing? Mark Vernon argues that positive psychology has overlooked and sidelined the ancient wisdom on wellbeing, notably from the Greek philosophers. Now is the time to pay it proper attention.Vernon shows, surprisingly, that wellbeing is not found in a focus on pleasure, or even the pursuit of happiness itself. Rather, it is a question of meaning and responding to the great challenge of our day: the search for transcendence. For at root, the life that is going well cultivates a way of life based upon love: it is that which draws you out of yourself - in friends, hopes and ultimately the contemplation of mystery - and orientates a life towards that which is good. (shrink)

Environment and Philosophy provides an accessible introduction to the radical challenges that environmentalism pose to concepts that have become almost second nature in the modern world. Written in an accessible way for those without a background in philosophy, this text examines ways of thinking about ourselves, nature and our relationship with nature.

While not an explicit claim of Hegel’s, this paper aims to use his analysis of ‘Conscience’ in the Phenomenology of Spirit to demonstrate that the conflict betweendifferent moral judgments is morally necessary. That is, rather than being the unfortunate result of ‘hard’ cases, I argue that moral conflict is a necessary condition for the possibility of duty. Grasping the moral ground of moral conflict, I contend, allows us to understand why such conflicts arise, how and why they become entrenched into (...) ‘moral issues’ and what our duties are in such cases. Thus, I aim to articulate both the moral necessity and dutiful resolution of seemingly intractable moral conflicts. (shrink)

The physics and metaphysics of identity and individuality Content Type Journal Article DOI 10.1007/s11016-010-9463-7 Authors Don Howard, Department of Philosophy and Graduate Program in History and Philosophy of Science, University of Notre Dame, Notre Dame, IN 46556, USA Bas C. van Fraassen, Philosophy Department, San Francisco State University, 1600 Holloway Avenue, San Francisco, CA 94132, USA Otávio Bueno, Department of Philosophy, University of Miami, Coral Gables, FL 33124, USA Elena Castellani, Department of Philosophy, University of Florence, Via Bolognese 52, 50139 (...) Florence, Italy Laura Crosilla, Department of Pure Mathematics, School of Mathematics, University of Leeds, Leeds, LS2 9JT UK Steven French, Department of Philosophy, University of Leeds, Leeds, UK Décio Krause, Department of Philosophy, Federal University of Santa Catarina, 88040-900 Campus Trindade, Florianópolis, SC Brazil Journal Metascience Online ISSN 1467-9981 Print ISSN 0815-0796. (shrink)

v. I. Graeco-Roman to early modern ethics -- v. 2. Modern and contemporary ethics.

Bionomics was a research approach invented by British biological scientists in the late nineteenth century and adopted by the American entomologist and evolutionist Vernon Lyman Kellogg in the early twentieth century. Kellogg hoped to use bionomics, which was the controlled observation and experimentation of organisms within settings that approximated their natural environments, to overcome the percieved weaknesses in the Darwinian natural selection theory. To this end, he established a bionomics laboratory at Stanford University, widely published results from his bionomic (...) investigations, and encouraged other biological researchers to adopt bionomics. (shrink)

An introduction to the philosophical implications of the recent surge of political and ethical interest in historical redress.

Steven French and Decio Krause examine the metaphysical foundations of quantum physics. They draw together historical, logical, and philosophical perspectives on the fundamental nature of quantum particles and offer new insights on a range of important issues. Focusing on the concepts of identity and individuality, the authors explore two alternative metaphysical views; according to one, quantum particles are no different from books, tables, and people in this respect; according to the other, they most certainly are. Each view comes with (...) certain costs attached and after describing their origins in the history of quantum theory, the authors carefully consider whether these costs are worth bearing. Recent contributions to these discussions are analyzed in detail and the authors present their own original perspective on the issues. The final chapter suggests how this perspective can be taken forward in the context of quantum field theory. (shrink)

“ Subsidiarity ” views of crime against humanity propose that state crime is at the core of the idea, thus necessitating a further level of authority. That proposal can be given a strong moral justification in terms of the enormous risks that arise from a state’s authority and territorial control. Discussions of crime against humanity by Larry May and Norman Geras, however, offer different views of the idea, May proposing that it be seen as group-based crime, Geras proposing that it (...) be seen as a serious violation of human rights. Those views are questioned on the basis of their fit with either the nature of the crimes involved or the moral basis of their condemnation, and the subsidiarity view is restated. (shrink)