Background In the wake of mandates for biomedical research to increase participation by members of historically underrepresented populations, community engagement (CE) has emerged as a key intervention to help achieve this goal.Methods Using interviews, observations, and document analysis, we examine how stakeholders in precision medicine research understand and seek to put into practice ideas about who to engage, how engagement should be conducted, and what engagement is for.Results We find that ad hoc, opportunistic, and instrumental approaches to CE exacted significant (...) consequences for the time and resources devoted to engagement and the ultimate impacts it has on research. Critical differences emerged when engagement and research decisionmaking were integrated with each other versus occurring in parallel, separate parts of the study organization, and whether community members had the ability to determine which issues would be brought to them for consideration or to revise or even veto proposals made upstream based on criteria that mattered to them. CE was understood to have a range of purposes, from instrumentally facilitating recruitment and data collection, to advancing community priorities and concerns, to furthering long-term investments in relationships with and changes in communities. These choices about who to engage, what engagement activities to support, how to solicit and integrate community input into the workflow of the study, and what CE was for were often conditioned upon preexisting perceptions and upstream decisions about study goals, competing priorities, and resource availability.Conclusions Upstream choices about CE and constraints of time and resources cascade into tradeoffs that often culminated in “pantomime community engagement.” This approach can create downstream costs when engagement is experienced as improvised and sporadic. Transformations are needed for CE to be seen as a necessary scientific investment and part of the scientific process. (shrink)

Diese Festschrift versammelt Texte zu den vielfältigen Forschungsinteressen von Alfred Schmidt, emeritierter Professor für Philosophie und Soziologie an der Universität Frankfurt am Main. Die philosophiehistorischen Betrachtungen versuchen jeweils, das Konzept eines realen Humanismus ins Bewusstsein gegenwärtiger praktischer Philosophie zu rufen. Verbindendes Motiv der Beiträge ist dabei ein kritisch verstandener Materialismus, der ohne weltanschauliche Versicherungen auskommt und den leibhaftigen Menschen in den Fokus der Betrachtung rückt. So verstandene Gesellschaftskritik orientiert sich an Gewährsmännern Kritischer Theorie wie etwa Hegel und Marx sowie Schopenhauer, (...) Nietzsche und Freud. Charakteristisch für die hier versammelten Texte ist unter anderem, dass sie eine subjektgerechte Einrichtung der Welt einfordern. (shrink)

Diese Festschrift versammelt Texte zu den vielfältigen Forschungsinteressen von Alfred Schmidt, emeritierter Professor für Philosophie und Soziologie an der Universität Frankfurt am Main. Die philosophiehistorischen Betrachtungen versuchen jeweils, das Konzept eines realen Humanismus ins Bewusstsein gegenwärtiger praktischer Philosophie zu rufen. Verbindendes Motiv der Beiträge ist dabei ein kritisch verstandener Materialismus, der ohne weltanschauliche Versicherungen auskommt und den leibhaftigen Menschen in den Fokus der Betrachtung rückt. So verstandene Gesellschaftskritik orientiert sich an Gewährsmännern Kritischer Theorie wie etwa Hegel und Marx sowie Schopenhauer, (...) Nietzsche und Freud. Charakteristisch für die hier versammelten Texte ist unter anderem, dass sie eine subjektgerechte Einrichtung der Welt einfordern. (shrink)

Recent work in cognitive psychology and experimental semantics indicates that people do not categorize natural kinds solely by virtue of their purported scientific essence. Two attempts have been made to explain away the data by appealing to the idea that participants in these studies are reasoning diagnostically. I will argue that an appeal to diagnostic reasoning will likely not help to explain away the data.

This book defends a form of ethical intuitionism, according to which (i) there are objective moral truths; (ii) we know some of these truths through a kind of immediate, intellectual awareness, or "intuition"; and (iii) our knowledge of moral truths gives us reasons for action independent of our desires. The author rebuts all the major objections to this theory and shows that the alternative theories about the nature of ethics all face grave difficulties.

This book provides answers to both normative and metaethical questions in a way that shows the interconnection of both types of questions, and also shows how a complete theory of reasons can be developed by moving back and forth between the two types of questions. It offers an account of the nature of intimate relationships and of the nature of the reasons that intimacy provides, and then uses that account to defend a traditional intuitionist metaethics. The book thus combines attention (...) to the details of the lived moral life – the context in which many of our most pressing moral questions arise, how we deliberate and make moral decisions, the complexities that plague our attempts to know what we ought to do – with theoretical rigor in offering an account of the nature of reasons, how we come to have moral knowledge, and how we can adjudicate between competing positions. (shrink)

The first edition of The Scientific Background to Modern Philosophy took the dialogue of science and philosophy from Aristotle through to Newton. This second edition adds eight chapters, taking the dialogue through the Enlightenment and up to Darwin. This anthology is an attempt to help bridge the gap between the history of science and the history of philosophy.

Part I: The representation of life -- Can life be given a real definition? -- The representation of the living individual -- The representation of the life-form itself -- Part II: Naive action theory -- Types of practical explanation -- Naive explanation of action -- Action and time -- Part III: Practical generality -- Two tendencies in practical philosophy -- Practices and dispositions as sources of the goodness of individual actions -- Practice and disposition as sources of individual action.

An important part of friendships are the so-called special obligations generated by them. Friends owe things to each other that they do not owe to strangers. While such special obligations are an important part of our everyday practice, they raise several philosophical questions. These questions include the status of special obligations (are such obligations sui generis or is it possible to reduce them to general moral principles?), the source of such special obligations (what grounds special obligations of friendship?), and the (...) content of special obligations (what is the content of special obligations of friendship?). This chapter gives an overview of some of the most important positions in the literature with regard to these questions. (shrink)

At the University of Sheffield during 2011 and 2012, a leading group of philosophers, psychologists, and others gathered to explore the nature and significance of implicit bias. The two volumes of Implicit Bias and Philosophy emerge from these workshops. Each volume philosophically examines core areas of psychological research on implicit bias as well as the ramifications of implicit bias for core areas of philosophy. Volume I: Metaphysics and Epistemology is comprised of two parts: “The Nature of Implicit Attitudes, Implicit Bias, (...) and Stereotype Threat,” and “Skepticism, Social Knowledge, and Rationality.” The first part contains chapters examining the relationship between implicit attitudes and “dual process” models of the mind; the role of affect in the formation and change of implicit associations; the unity (or disunity) of implicit attitudes; whether implicit biases are mental states at all; and whether performances on stereotype-relevant tasks are automatic and unconscious or intentional and strategic. The second part contains chapters examining implicit bias and skepticism; the effects of implicit bias on scientific research; the accessibility of social stereotypes in epistemic environments; the effects of implicit bias on the self-perception of members of stigmatized social groups as rational agents; the role of gender stereotypes in philosophy; and the role of heuristics in biased reasoning. (shrink)

Externalist theories of justification create the possibility of cases in which everything appears to one relevantly similar with respect to two propositions, yet one proposition is justified while the other is not. Internalists find this difficult to accept, because it seems irrational in such a case to affirm one proposition and not the other. The underlying internalist intuition supports a specific internalist theory, Phenomenal Conservatism, on which epistemic justification is conferred by appearances.

The two dominant contemporary moral theories, Kantianism and utilitarianism, have difficulty accommodating our commonsense understanding of friendship as a relationship with significant moral implications. The difficulty seems to arise from their underlying commitment to impartiality, to the claim that all persons are equally worthy of concern. Aristotelian accounts of friendship are partialist in so far as they defend certain types of friendship by appeal to the claim that some persons, the virtuous, are in fact more worthy of concern than are (...) other persons. This article argues that we can preserve the underlying impartiality of Kantianism and utilitarianism, while also preserving a certain partiality with respect to our friends: the partiality of commonsense only seems objectionable if we fail to understand the true grounds, nature, and implications of such partiality. Neo-Aristotelian partiality should be rejected in favor of commonsense partiality. (shrink)

The two dominant contemporary moral theories, Kantianism and utilitarianism, have difficulty accommodating our commonsense understanding of friendship as a relationship with significant moral implications. The difficulty seems to arise from their underlying commitment to impartiality, to the claim that all persons are equally worthy of concern. Aristotelian accounts of friendship are partialist in so far as they defend certain types of friendship by appeal to the claim that some persons, the virtuous, are in fact more worthy of concern than are (...) other persons. This article argues that we can preserve the underlying impartiality of Kantianism and utilitarianism, while also preserving a certain partiality with respect to our friends: the partiality of commonsense only seems objectionable if we fail to understand the true grounds, nature, and implications of such partiality. Neo-Aristotelian partiality should be rejected in favor of commonsense partiality. (shrink)

_Philosophy Through Film_ offers a uniquely engaging and effective approach to introductory philosophy by combining an anthology of classical and contemporary philosophical readings with a discussion of philosophical concepts illustrated in popular films. Pairs 50 classical and contemporary readings with popular films - from Monty Python and _The Matrix_ to _Casablanca_ and _A Clockwork Orange_ Addresses key areas in philosophy, including topics in ethics, philosophy of religion, philosophy of mind, free will and determinism, the problem of perception, and philosophy of (...) time Each unit begins with an extensive introduction by the editors and ends with study questions linking readings to films Features chapter by chapter discussion of clips from films that vividly illustrate the critical philosophical arguments and positions raised in the readings. (shrink)

Methadone maintenance treatment (MMT) is a harm reduction approach for persons who wish to stop using opioids and is rather effective if used for a minimum of 12 months. Notably, research demonstrates that many persons enrolled in MMT programs discontinue care before this time, limiting its effects. To better understand this process, we undertook an exploratory descriptive qualitative study and interviewed 12 men and women who were using MMT. Using the theoretical work of Foucault and Hardt and Negri, the interview (...) data highlighted that MMT continues to be strongly stigmatized, and that it is a system of care that involves rewards and penalties, based on if patients behave according to prescribed norms. These results suggest that MMT is a disciplinary mechanism, albeit one that impedes its own access. We consequently recommend that healthcare providers work to facilitate access to MMT, which means altering care delivery. (shrink)

Conserved upstream open reading frames (uORFs) are found within many eukaryotic transcripts and are known to regulate protein translation. Evidence from genetic and bioinformatic studies implicates disturbed uORF‐mediated translational control in the etiology of human diseases. A genetic mouse model has recently provided proof‐of‐principle support for the physiological relevance of uORF‐mediated translational control in mammals. The targeted disruption of the uORF initiation codon within the transcription factor CCAAT/enhancer binding protein β (C/EBPβ) gene resulted in deregulated C/EBPβ protein isoform expression, associated (...) with defective liver regeneration and impaired osteoclast differentiation. The high prevalence of uORFs in the human transcriptome suggests that intensified search for mutations within 5′ RNA leader regions may reveal a multitude of alterations affecting uORFs, causing pathogenic deregulation of protein expression. (shrink)

Most of us accept that we have special obligations to our family members: to, e.g., our parents, our siblings, and our grandparents. But it is extremely difficult to offer a plausible grounding for such obligations, given the apparent fact that familial relationships are not voluntarily entered. I did not choose to be my mother's daughter or my brother's sister, so why suppose that such facts about me are morally significant? Why suppose that I owe more to my mother or to (...) my brother than natural duty requires that I do for all and any persons? Special obligations appear more problematic the less the relationships that supposedly generate them are akin to the relationship between promiser and promisee, a voluntarily assumed relationship. Thus, for example, special obligations to friends might appear less problematic than do those to family members, because it seems that we voluntarily choose our friends, and, thus, voluntarily choose to bear more for them than natural duty requires. (shrink)

In this engaging and spirited text, Michael Lynch argues that truth does matter, in both our personal and political lives. He explains that the growing cynicism over truth stems in large part from our confusion over what truth is.

Recent experimental studies have claimed to find evidence for the view that natural kind terms such as “water” are ambiguous: that they have two extensions, one determined by superficial properties, the other by underlying essence. In an online experiment, we presented to 600 participants scenarios describing discoveries of novel samples that differ in deep structure from samples of a familiar kind but are superficially identical, such as a water-like substance that is not composed of H2O. We used three different types (...) of question sets to probe whether the participants considered the sample as a member of the kind or not. Our results did not confirm the predictions of the ambiguity view. They were, rather, consistent with views that take underlying essences to be the sole criterion for membership in a natural kind. (shrink)

Causation: A Realist Approach Traditional empiricist accounts of causation and laws of nature have been reductionist in the sense of entailing that given a complete specification of the non-causal properties of and relations among particulars, it is therefore logically determined both what laws there are and what events are causally related. It is argued here, however, that reductionist accounts of causation and of laws of nature are exposed to decisive objections, and thus that the time has come for empiricists to (...) break with that tradition. -/- The basic goal of this book, therefore, is to set out and defend realistic accounts of those concepts. In the case of causal relations, for example, Tooley maintains that causation is basically a matter of theoretical relations between states of affairs that underlie and explain relative frequencies. He also argues that such an approach avoids the objections that tell against reductionist accounts and that it does so without making causal relations epistemologically inaccessible. (shrink)

Samuel Scheffler has identified two important objections to associative obligations, the voluntarist objection and the distributivist objection. The voluntarist is concerned about protecting the autonomy of the agent who is supposed to have associative obligations. However, the appropriate account of the source of associative obligations reveals that they pose no threat to autonomy, if we understand autonomy in a weak rather than a strong sense. The distributivist is worried about the claims of outsiders being ignored as the result of insiders (...) having associative obligations to one another. This objection loses much of its force when we understand the genuine implications of associative obligations. (shrink)

Dignity plays a central role in current thinking about law and human rights, but there is sharp disagreement about its meaning. Combining conceptual precision with a broad historical background, Michael Rosen puts these controversies in context and offers a novel, constructive proposal. “Penetrating and sprightly...Rosen rightly emphasizes the centrality of Catholicism in the modern history of human dignity. His command of the history is impressive...Rosen is a wonderful guide to the recent German constitutional thinking about human dignity...[Rosen] is in (...) general an urbane and witty companion, achieving his aim of accessibly written philosophy.” —Samuel Moyn, The Nation “[An] elegant, interesting and lucid exploration of the concept of dignity...Drawing on classical, liberal and Catholic traditions, Rosen hopes to rehabilitate dignity to its rightful place near the centre of moral thought...Rosen's admirable book deserves wide attention from political theorists, jurisprudes and political philosophers.” —Simon Blackburn, Times Higher Education “Dignity deserves to be widely read, not only for its intrinsic interest, but also as a corrective to the habit of discussing such topics in abstraction from their social context. Whether or not one agrees with Rosen's arguments, there can be no doubt he has widened our horizons.” —Rae Langton, Times Literary Supplement. (shrink)

Michael G. Titelbaum presents a new Bayesian framework for modeling rational degrees of belief—the first of its kind to represent rational requirements on agents who undergo certainty loss.

edition (unseen), $12.95. traditions, bringing into being new modes of understanding. Paper Anthropology, and particularly ethnography, is torn between two quests, one to capture the diversity of social life and the other to discover universal principles structuring that diversity. Jackson examines these quests within the context of ethnographic fieldwork, focusing on the relationship between ethnographers and the people they study. He is concerned with defining the anthropological project as something more than the projection of the anthropologist's traditions and concerns onto (...) an alien culture. Rather, he would have the project open a genuine dialogue between people from different cultures or Annotation copyrighted by Book News, Inc., Portland, OR. (shrink)

Reasons of intimacy, i.e. reasons to care for friends and other intimates, resist categorization as either subjective Humean reasons or as objective consequentialist reasons. Reasons of intimacy are grounded in the friendship relation itself, not in the psychological attitudes of the agent or in the objective intrinsic value of the friend or the friendship. So reasons of intimacy are objective and agent-relative and can be understood by analogy with reasons of fidelity and reasons of prudence. Such an analogy can help (...) us to understand which objective agent-relative reasons we have and which, such as deontological constraints, we do not have. (shrink)

Philosophers who, in the light of these attacks, have attempted to vindicate the motive of duty have done so in a half-hearted way, by stressing the motive of duty’s function as a secondary or limiting motivation, or by denying “that acting from duty primarily concerns isolated actions.” I will defend duty as a primary motive with respect to isolated actions. Critics of acting from duty and philosophers who have attempted to respond to them have done little work spelling out exactly (...) what it is for an agent to act from duty. To act explicitly on moral principle is to act from a type of concern for persons that is no less morally good than concern expressed in direct emotional responses. Concern mediated by moral principles is, in certain ways, morally superior to that expressed in direct emotional responses, even when the object of concern is an intimate such as a friend or loved one. (shrink)

In this paper, I propose a new way of defining sport that I call a ‘core-periphery’ model. According to a core-periphery model, sport comes in degrees – what I refer to as ‘sport-likeness’ – and the aim of the philosopher of sport is to chart those dimensions along which an activity can be more or less a sport. By introducing the concept of sport-likeness, the core-periphery model complicates the picture of what is or is not a sport and encourages philosophers (...) interested in defining sport to engage with the social sciences in exploring the extension of the term sport in common usage. In this paper I present the results of a small survey about attitudes to sport, and use it to illustrate how a core-periphery definition of sport would proceed. (shrink)

Reasons of intimacy, i.e. reasons to care for friends and other intimates, resist categorization as either subjective Humean reasons or as objective consequentialist reasons. Reasons of intimacy are grounded in the friendship relation itself. not in the psychological attitudes of the agent or in the objective intrinsic value of the friend or the friendship. So reasons of intimacy are objective and agent‐relative and can be understood by analogy with reasons of fidelity and reasons of prudence. Such an analogy can help (...) us to understand which objective agent‐relative reasons we have and which, such as deontological constraints, we do not have. (shrink)

Situado no norte da África durante a antiguidade tardia, o pensamento político de Santo Agostinho não está sistematizado em um conjunto teórico de obras. É fruto de sua reflexão sobre problemas concretos como a legitimidade de intervenção estatal em querelas religiosas como o conflito entre católicos e donatistas. A visão agostiniana de Estado prevê um engajamento do cristão na esfera política, não no sentido da teocracia medieval, mas tendo em vista sua purificação moral. Acredita que ele deva intervir na esfera (...) privada da fé para evitar a violência extrema, mas não crê que suas instituições possam ser justas se não orientadas pela verdadeira piedade da fé cristã. Para Agostinho uma das razões para a decadência social de Roma é sua crença em falsas narrativas que não levaram os cidadãos a um crescimento moral autêntico, no que em sua visão a Igreja pode e deve colaborar com o Estado. (shrink)

RESUMO: Na reflexão que desenvolve nos textos do primeiro decênio de sua obra Agostinho mantém um princípio teleológico forte, a saber, que o grande motivo que leva o homem a filosofar e buscar a compreensão da Verdade é o desejo de ser feliz, isto é, encontrar a Beatitude que ele identifica com a condição de estar plenamente em Deus, fim último a ser buscado pelo homem. Este fim só é atingido por quem compreende a Verdade com a reta razão e (...) vive a virtude com reta vontade. Trata-se de um processo cognitivo e volitivo onde a ação humana precisa estar em conformidade com uma realidade transcendente, exterior à natureza criada, que lhe está na condição de um mandato de ação. Neste ponto percebemos a presença de um elemento deontológico forte já nesta fase de seu pensamento, o qual não esvazia sua ampla reflexão acerca da liberdade humana, mas a situa no contexto da teodiceia que justifica sua moral religiosa. (shrink)

While philosophers hold that it is patently absurd to blame robots or hold them morally responsible [1], a series of recent empirical studies suggest that people do ascribe blame to AI systems and robots in certain contexts [2]. This is disconcerting: Blame might be shifted from the owners, users or designers of AI systems to the systems themselves, leading to the diminished accountability of the responsible human agents [3]. In this paper, we explore one of the potential underlying reasons for (...) robot blame, namely the folk's willingness to ascribe inculpating mental states or "mens rea" to robots. In a vignette-based experiment (N=513), we presented participants with a situation in which an agent knowingly runs the risk of bringing about substantial harm. We manipulated agent type (human v. group agent v. AI-driven robot) and outcome (neutral v. bad), and measured both moral judgment (wrongness of the action and blameworthiness of the agent) and mental states attributed to the agent (recklessness and the desire to inflict harm). We found that (i) judgments of wrongness and blame were relatively similar across agent types, possibly because (ii) attributions of mental states were, as suspected, similar across agent types. This raised the question - also explored in the experiment - whether people attribute knowledge and desire to robots in a merely metaphorical way (e.g., the robot "knew" rather than really knew). However, (iii), according to our data people were unwilling to downgrade to mens rea in a merely metaphorical sense when given the chance. Finally, (iv), we report a surprising and novel finding, which we call the inverse outcome effect on robot blame: People were less willing to blame artificial agents for bad outcomes than for neutral outcomes. This suggests that they are implicitly aware of the dangers of overattributing blame to robots when harm comes to pass, such as inappropriately letting the responsible human agent off the moral hook. (shrink)

This volume presents a selection of the most influential recent discussions of the crucial metaphysical questions: what is it for one event to cause another? The subject of causation bears on many topics, such as time, explanation, mental states, the laws of nature, and the philosphy of science.

Time may be infinite in both directions. If it is, then, if persons could live at most once in all of time, the probability that you would be alive now would be zero. But if persons can live more than once, the probability that you would be alive now would be nonzero. Since you are alive now, with certainty, either the past is finite, or persons can live more than once.