The comprehension of living organisms in all their complexity poses a major challenge to the biological sciences. Recently, systems biology has been proposed as a new candidate in the development of such a comprehension. The main objective of this paper is to address what systems biology is and how it is practised. To this end, the basic tools of a systems biological approach are explored and illustrated. In addition, it is questioned whether systems biology ‘revolutionizes’ molecular biology and ‘transcends’ its (...) assumed reductionism. The strength of this claim appears to depend on how molecular and systems biology are characterised and on how reductionism is interpreted. Doing credit to molecular biology and to methodological reductionism, it is argued that the distinction between molecular and systems biology is gradual rather than sharp. As such, the classical challenge in biology to manage, interpret and integrate biological data into functional wholes is further intensified by systems biology’s use of modelling and bioinformatics, and by its scale enlargement. (shrink)

Report of the symposium 'Towards a Philosophy of Systems Biology' held at the Vrije Universiteit of Amsterdam (VUA), the Netherlands, from 2 to 3 June 2005.

Via a historical reconstruction, this paper primarily demonstrates how the societal debate on genetically modified organisms (GMOs) gradually extended in terms of actors involved and concerns reflected. It is argued that the implementation of recombinant DNA technology out of the laboratory and into civil society entailed a “complex of concerns.” In this complex, distinctions between environmental, agricultural, socio-economic, and ethical issues proved to be blurred. This fueled the confusion between the wider debate on genetic modification and the risk assessment of (...) transgenic crops in the European Union. In this paper, the lasting skeptical and/or ambivalent attitude of Europeans towards agro-food biotechnology is interpreted as signaling an ongoing social request – and even a quest – for an evaluation of biotechnology with Sense and Sensibility. In this (re)quest, a broader-than-scientific dimension is sought for that allows addressing the GMO debate in a more “sensible” way, whilst making “sense” of the different stances taken in it. Here, the restyling of the European regulatory frame on transgenic agro-food products and of science communication models are discussed and taken to be indicative of the (re)quest to move from a merely scientific evaluation and risk-based policy towards a socially more robust evaluation that takes the “non-scientific” concerns at stake in the GMO debate seriously. (shrink)

Godenschemering van Daniël de Waele is een theologische cultuurgeschiedenis die de evolutie van het geloof in God uitdiept in de loop der tijd. Israël ontdekte in een polytheïstische wereld de Ene God, die door de tijd heen steeds humaner werd en dichterbij kwam. Hoe is het geloof na die grote stap geëvolueerd? Hoe past het verdampen van het geloof, dat uiteindelijk eindigde in de dood van God, in deze evolutie? En welke rol heeft het bestormen van de godenbeelden gespeeld? (...) De Waele ontwaart naast deze geloofsevolutie een andere geschiedenis: een blijvende zoektocht naar de ene God. (shrink)

Presumed catholic or christian influence inside the french speaking green party of Belgium is a very strong stereotype since 1981. Nevertheless no scientific work has ever proved that supposition. Starting from a large survey among the 2 500 Ecolo's members, the authors examine and analyze the inventory of fixtures. They present the main features of the members and distinguish the outlines of catholic and non-catholic's members.

This paper analyses the actual meaning of a transcendental philosophy of biology, and does so by exploring and actualising the epistemological and metaphysical value of Kant's viewpoint on living systems. It finds inspiration in the Kantian idea of living systems intrinsically resisting objectification, but critically departs from Kant's philosophical solution in as far as it is based in a subjectivist dogmatism. It attempts to overcome this dogmatism, on the one hand by explicitly taking into account the conditions of possibility at (...) the side of the subject, and on the other hand by embedding both the living and the knowing system into an ontology of complexly organized dynamical systems. This paper fits into the transcendental perspective in acknowledging the need to analyse the conditions of knowability, prior to the contents of what is known. But it also contributes to an expansion and an actualisation of the issue of transcendentality itself by considering the conditions of possibility at the side of the object as intrinsically linked to the conditions of possibility at the side of the subject. (shrink)

The comprehension of living organisms in all their complexity poses a major challenge to the biological sciences. Recently, systems biology has been proposed as a new candidate in the development of such a comprehension. The main objective of this paper is to address what systems biology is and how it is practised. To this end, the basic tools of a systems biological approach are explored and illustrated. In addition, it is questioned whether systems biology ‘revolutionizes’ molecular biology and ‘transcends’ its (...) assumed reductionism. The strength of this claim appears to depend on how molecular and systems biology are characterised and on how reductionism is interpreted. Doing credit to molecular biology and to methodological reductionism, it is argued that the distinction between molecular and systems biology is gradual rather than sharp. As such, the classical challenge in biology to manage, interpret and integrate biological data into functional wholes is further intensified by systems biology’s use of modelling and bioinformatics, and by its scale enlargement. (shrink)

Meeting 5G high bandwidth rates, ultra-low latencies, and high reliabilities requires of network infrastructures that automatically increase/decrease the resources based on their customers’ demand. An autonomous and dynamic management of a 5G network infrastructure represents a challenge, as any solution must account for the radio access network, data plane traffic, wavelength allocation, network slicing, and network functions’ orchestration. Furthermore, federation among administrative domains (ADs) must be considered in the network management. Given the increased dynamicity of 5G networks, artificial intelligence/machine learning (...) (AI/ML) solutions are strong candidates able to learn, and take quick provisioning decisions upon fast changes in network conditions. Therefore, this chapter presents an analysis of the state-of-the-art solutions for 5G networks’ management, where AI/ML solutions are discussed and compared with traditional methods. Additionally, the chapter provides a technology overview of both standards, and existing solutions regarding the 5G network management, and directions toward the integration of AI/ML in 5G networks. (shrink)

Via a historical reconstruction, this paper primarily demonstrates how the societal debate on genetically modified organisms (GMOs) gradually extended in terms of actors involved and concerns reflected. It is argued that the implementation of recombinant DNA technology out of the laboratory and into civil society entailed a “complex of concerns.” In this complex, distinctions between environmental, agricultural, socio-economic, and ethical issues proved to be blurred. This fueled the confusion between the wider debate on genetic modification and the risk assessment of (...) transgenic crops in the European Union. In this paper, the lasting skeptical and/or ambivalent attitude of Europeans towards agro-food biotechnology is interpreted as signaling an ongoing social request – and even a quest – for an evaluation of biotechnology with Sense and Sensibility. In this (re)quest, a broader-than-scientific dimension is sought for that allows addressing the GMO debate in a more “sensible” way, whilst making “sense” of the different stances taken in it. Here, the restyling of the European regulatory frame on transgenic agro-food products and of science communication models are discussed and taken to be indicative of the (re)quest to move from a merely scientific evaluation and risk-based policy towards a socially more robust evaluation that takes the “non-scientific” concerns at stake in the GMO debate seriously. (shrink)

Dit boekt brengt negen opstellen samen van Gentse filosofen en godsdienstwetenschappers. Etienne Vermeersch, Freddy Mortier, Johan Braeckman met Stefaan Blancke, Rik Pinxten, Patrick Loobuyck, Balagangadhara Rao met Sarah Claerhout, Benjamin Biebuyck, Nel Grillaert, en Danny Praet leveren, elk vanuit hun eigen interesses en expertises, kritische bijdragen over de complexe relatie tussen christendom en filosofie: wijsgerige kritiek op het christendom en christelijk gebruik van de filosofie. Vanuit het ruimere perspectief van de interactie tussen wijsbegeerte, wereldbeeld en wetenschappen bestrijken de elf (...) auteurs de volledige periode van het vroege christendom tot het hedendaagse fundamentalisme. Het boek bevat zowel historische als theoretische benaderingen. Drie bijdragen hebben het werk en de impact van Nietzsche tot thema, drie bespreken verschillende aspecten van het fundamentalisme. Thema’s zoals het geloof in een hiernamaals, de relatie tussen christenen en niet-christenen, de impact van het christendom op het westerse wereldbeeld en de benadering van andere culturen, en de radicale kritiek van filosofen op het theïsme en de christelijke moraal maken van deze bundel een uitzonderlijk rijke collectie die lezers met diverse interesses zal aanspreken. (shrink)

Desde a sua génese, a Arqueologia encontra-se entre as ciências naturais e as ciências sociais e humanísticas. Esta posição partilhada e a procura de uma maior compreensão dos seus objetos de estudo específicos, criou nos profissionais de Arqueologia uma necessidade de recorrerem a várias metodologias (e tecnologias) originárias de outras disciplinas. De forma similar a outras ciências, a Arqueologia é uma área permeável à experimentação e aplicação de conceitos teórico-práticos exógenos que levou, inclusive, à formação de diversas especialidades que unem (...) a Arqueologia e outras áreas, como a Zooarqueologia. Como aconteceu ao longo da sua história, o meio académico está perante um momento de mudança na forma como se processa a aquisição de conhecimento. O fato de estarmos na Era Digital da globalização faz com que a adaptação do meio académico a esta realidade seja mais continuada, não sendo a Arqueologia alheia a esta transformação. Após uma breve introdução ao novo "paradigma digital" das humanidades, revemos alguns dos principais usos de tecnologias relacionadas com o uso da Internet no apoio à investigação em Arqueologia (e.g., bases de dados enriquecidas), e descrevemos algumas questões relacionadas com o uso de novas ferramentas e técnicas, seus principais obstáculos e tendências. (shrink)

The article inquires about the role of language in Cristina Peri Rossi’s Panic Signs [Indicios pánicos]. The hypothesis of the work is that language, as a mimetic instrument of representation and creation, established itself as a way to upgrade the relations of power during the Uruguayan pre-dictatorship. Being a qualitative research based on a hermeneutical approach, the article has the following aims: i) reconstruct the background to the dictatorship leaded by Juan Maria Bordaberry, ii) frame the work within the tradition (...) of dictator novel following Lukács’ socio-critical approach and Pierre Bourdieu’s field theory, iii) explain how language works as an instrument of representation and power, iv) analyze Peri Rossi’s work in the light of the aforementioned framework. It concludes, first, that the work responds to a mimetic language of representation, which involves taking a stance that is based on the notions of hegemony or counter-hegemony; and, second, that provided the scarce studies concerning the circumstantial situations of the work, the article might be regarded as a significant contribution to literary criticism. (shrink)

El estudio de dos formularios notariales del siglo vii/xiii, uno sirio y el otro andalusí, muestra que el discurso sobre las modalidades de comunicación escrita preceptuadas para los jueces refleja una estrecha relación entre la doctrina y la realidad de la práctica legal. Uno de los aspectos de esta relación es el cambio que tuvo que experimentar la doctrina discursiva bajo la presión de las prácticas judiciales cotidianas.

At the provincial council elections of the 13th of October 1985 in Belgium two of the three traditional politie al families made a general progress, namely the socialists and the christian democrats. The liberals had a serious decline in Flanders, but for the greater part this was counterbalanced by the liberal progress in Wallonia. The ecologists also made progress, mostly in the Flemish part of the country. Beside the Flemish liberals, the big losers of these elections were the regional parties, (...) namely the Flemish nationalists and for sure the Walloon Rally who disappeared from the electoral scene. (shrink)

At the provincial council elections of the 13th of december 1987 only one of the three traditional political families made a general progress, namely the socialists. Mainly in Wallonia the socialists improved their position seriously. In this part of the country they are the only and absolute winners of these provincial elections. The christian-democrats and the liberals were subject of a severe decline. Por the christian-democrats this decline was mainly situated in Flanders. The liberals had a serious decline in W (...) allonia, that couldn't be counterbalanced by the small progress they made in Flanders. The ecologists made progress, mostly in the Flemish part of the country and in Brussels. By the federalist parties the Volksunie had a loss of three provincial council seats in Flanders, but the seperatistic and extreme right party Vlaams Blok won two seats. The communists disappeared totally from the provincial councils in Belgium. The results of the provincial council elections had a similar profile as these of the House of Representatives and the Senate which where held at the same day. (shrink)

Jean-Luc Nancy élabore, depuis quelques années, une philosophie première où le concept d’« être-avec » occupe une place centrale. Celui-ci a suscité son lot d'interprétations. Une des critiques faite à l’encontre du concept est articulée selon l’angle éthique, plus particulièrement en ce qui a trait à la pluralité. En effet, en amalgamant « être » et « avec », Nancy annihilerait, comme Heidegger, la nécessaire pluralité de la vie en commun. C’est ce débat que nous voulons ici commenter. Nous commencerons (...) en explicitant le concept d’être-avec chez Nancy. Dans un deuxième temps, nous développerons les arguments de ceux qui reprochent à Nancy de ne pas avoir réussi à faire droit à la pluralité. Pour nous aider à y voir plus clair, nous utiliserons les travaux de Franco Volpi et de Jacques Taminiaux qui ont analysé les causes de ce déni heideggérien de la pluralité. Nous présenterons leur investigation dans la troisième section. Enfin, nous montrerons que l’être-avec nancéen, bien loin de dénier la pluralité, lui donne toute son ampleur. (shrink)

Le rôle des mathématiques dans la formation des officiers de l’armée néerlandaise, a profondément changé pendant le premier xixe siècle avec la fondation de l’Académie militaire en 1828. Les mathématiques étaient au centre de la formation. L’Académie était un des lieux les plus importants de diffusion des connaissances mathématiques aux Pays-Bas pendant la première moitié du xixe siècle, mais elle a perdu ce rôle pendant les années 1860-1870. Dans cet article, je me propose d’examiner à la fois les programmes de (...) l’Académie et le rôle central des enseignants de mathématiques de l’Académie dans la Société Mathématique néerlandaise et dans l’Académie royale des Sciences. Par ailleurs, l’évolution des mathématiques, visible dans ces deux institutions dans les années 1850, n’a pas entraîné une adaptation des programmes au sein de l’Académie. Ainsi, à partir de 1870, l’Académie a presque complètement disparu de la vie mathématique des Pays-Bas. The role of mathematics in the education of Dutch army officers changed dramatically in the early 19th century. This shift became visible with the founding of the Dutch Royal Military Academy in 1828, which shows the role of mathematics in military education shifting toward a purely pedagogical function. This change in approach, which primarily occurred in 1860’s, affected the standing and perception of an academy once highly respected in the field of mathematics. In the present work, I examine both the curricula at the Academy and the crucial role of the Academy’s mathematics instructors in the Dutch Mathematical Society and the Royal Academy of Sciences. Importantly, these two institutions managed to successfully adapt to the changing character of mathematical sciences that occurred around 185 Mathematicians at the Royal Military Academy, however, appeared to cling to an outdated view of mathematics. Failing to update their approach ultimately caused the Academy to lose its once prominent place in the Dutch mathematical community. (shrink)

Le rôle des mathématiques dans la formation des officiers de l’armée néerlandaise, a profondément changé pendant le premier xixe siècle avec la fondation de l’Académie militaire en 1828. Les mathématiques étaient au centre de la formation. L’Académie était un des lieux les plus importants de diffusion des connaissances mathématiques aux Pays-Bas pendant la première moitié du xixe siècle, mais elle a perdu ce rôle pendant les années 1860-1870. Dans cet article, je me propose d’examiner à la fois les programmes de (...) l’Académie et le rôle central des enseignants de mathématiques de l’Académie dans la Société Mathématique néerlandaise et dans l’Académie royale des Sciences. Par ailleurs, l’évolution des mathématiques, visible dans ces deux institutions dans les années 1850, n’a pas entraîné une adaptation des programmes au sein de l’Académie. Ainsi, à partir de 1870, l’Académie a presque complètement disparu de la vie mathématique des Pays-Bas. The role of mathematics in the education of Dutch army officers changed dramatically in the early 19th century. This shift became visible with the founding of the Dutch Royal Military Academy in 1828, which shows the role of mathematics in military education shifting toward a purely pedagogical function. This change in approach, which primarily occurred in 1860’s, affected the standing and perception of an academy once highly respected in the field of mathematics. In the present work, I examine both the curricula at the Academy and the crucial role of the Academy’s mathematics instructors in the Dutch Mathematical Society and the Royal Academy of Sciences. Importantly, these two institutions managed to successfully adapt to the changing character of mathematical sciences that occurred around 185 Mathematicians at the Royal Military Academy, however, appeared to cling to an outdated view of mathematics. Failing to update their approach ultimately caused the Academy to lose its once prominent place in the Dutch mathematical community. (shrink)

Le rôle des mathématiques dans la formation des officiers de l’armée néerlandaise, a profondément changé pendant le premier xixe siècle avec la fondation de l’Académie militaire en 1828. Les mathématiques étaient au centre de la formation. L’Académie était un des lieux les plus importants de diffusion des connaissances mathématiques aux Pays-Bas pendant la première moitié du xixe siècle, mais elle a perdu ce rôle pendant les années 1860-1870. Dans cet article, je me propose d’examiner à la fois les programmes de (...) l’Académie et le rôle central des enseignants de mathématiques de l’Académie dans la Société Mathématique néerlandaise et dans l’Académie royale des Sciences. Par ailleurs, l’évolution des mathématiques, visible dans ces deux institutions dans les années 1850, n’a pas entraîné une adaptation des programmes au sein de l’Académie. Ainsi, à partir de 1870, l’Académie a presque complètement disparu de la vie mathématique des Pays-Bas. The role of mathematics in the education of Dutch army officers changed dramatically in the early 19th century. This shift became visible with the founding of the Dutch Royal Military Academy in 1828, which shows the role of mathematics in military education shifting toward a purely pedagogical function. This change in approach, which primarily occurred in 1860’s, affected the standing and perception of an academy once highly respected in the field of mathematics. In the present work, I examine both the curricula at the Academy and the crucial role of the Academy’s mathematics instructors in the Dutch Mathematical Society and the Royal Academy of Sciences. Importantly, these two institutions managed to successfully adapt to the changing character of mathematical sciences that occurred around 185 Mathematicians at the Royal Military Academy, however, appeared to cling to an outdated view of mathematics. Failing to update their approach ultimately caused the Academy to lose its once prominent place in the Dutch mathematical community. (shrink)

Pastoral power and techniques of the self: Foucault and the asceticism of the Desert Fathers This article argues that Foucault would probably have wanted to discuss a number of subjects and texts which are now almost completely lacking: the novelistic texts known as the Apocryphal Acts of the Apostles and some hagiographical sources. The Christian views on sexuality were sometimes less ‘orthodox’ and more extreme than what Foucault presented, probably under the influence of Paul Veyne. The Life of Anthony by (...) Athanasius contains a passage which is not analyzed thoroughly in the volume as it was published but which is a key text for the development of Christian hermeneutics and pastoral power. (shrink)

En el presente artículo se propone crear un margen conceptual para la construcción de una criminología fenomenológica que aborde el conocimiento de cómo se interpretan las conductas de las personas a través de las percepciones de otros, enfocado a la constitución de la conducta criminal, delincuencial, violenta o antisocial, que, siendo estos provenientes de la naturaleza de variadas ciencias, provoca tener horizontes amplios en el entendimiento que en la misma esencia lo vuelven complejo, la criminología actual, tiene en sí, varios (...) objetos de estudio que ha tomado de aquellas ciencias que tienen en su qué hacer lo relacionado con el crimen, de tal modo, desde el derecho, se estudia el delito y sus elementos, desde la psiquiatría y psicología, la conducta antisocial y su desarrollo, de la sociología, la conducta desviada patológica y su formación, el trabajo social, aporta otras interpretaciones, lo mismo, cuando corresponde a la antropología de la violencia, su historia, percepciones, cambios culturales, entre muchas otras. En ello radica la complejidad en la armonización de objetos de estudio que encuentran reunión en la criminología en una integración interdisciplinaria, pero esta se agota ante la abrumante realidad criminal que afecta a la aldea global, donde poco tiempo permite a la reflexión, necesitando con urgencia la intervención. El caso abordado aquí, es dar esa aproximación a una criminología fenomenológica, que pasará previo a su desarrollo, por el proceso de especialización de la criminología, soltando por momentos el paradigma clásico, para avanzar al futuro en la sistematización de teorías de otras ciencias, para generar un banco de conocimientos, que permitirán a posteriori, desarrollar sus propias concepciones e interpretaciones. No hay algo malo en la especialización, es parte de la evolución y maduración. (shrink)

Together with the city council elections, the citizens of Antwerp elected on 8 October 2000 nine district councils. This new decentralised political level is primarily initiated to restore the confidence of the citizens in the city government. By analysing the results of the city and the district elections we try to find indications whether citizens feel closer to their new district governments or not. Apparently district elections resulted neither in a higher voter turn-out, nor in less blank votes. Nevertheless, there (...) is a significant correlation of voter turn-out and blank votes with population of the districts. And although the differences between the electoral results of the city elections and the district elections are not huge, a different political landscape comes more or less into existence in the several districts. Quite surprisingly the number of list votes is higher on the district elections than on the city elections, while we would have expected a higher number of preferential votes. Correctingfor incumbents and famous candidates on the lists, our initial expectations hold much better. Generally spoken, we can conclude that the district elections do not give much proof of a closer connection between the citizens and the city government. Nevertheless we find some important differences between the districts. (shrink)

The permissibility of actions depends upon facts about the flourishing and separateness of persons. Persons differ from other creatures in having the task of discovering for themselves, by conjecture and refutation, what sort of life will fulfil them. Compulsory slavery impermissibly prevents some persons from pursuing this task. However, many people may conjecture that they are natural slaves. Some of these conjectures may turn out to be correct. In consequence, voluntary slavery, in which one person welcomes the duty to fulfil (...) all the commands of another, is permissible. Life-long voluntary slavery contracts are impermissible because of human fallibility; but fixed-term slavery contracts should be legally enforceable. Each person has the temporarily alienable moral right to direct her own life. (shrink)

El libro de Osvaldo Torres Gutiérrez, es un trabajo descriptivo, bien documentado y fundamentado en el uso de fuentes y bibliografía general y específica sobre el tema en cuestión, siendo uno de los aspectos más importantes las entrevistas realizadas a dirigentes de las dos organizaciones político revolucionarias que son el centro de su análisis.En las primeras líneas, el autor deja establecida la pregunta sobre la cual girará su trabajo, “por qué dos organizaciones de la izquierda revolucion..

A central problem of political philosophy is that of explaining how a state could have the moral authority to enforce laws, promulgate laws which citizens are thereby obliged to obey, give new duties to citizens and levy taxes. Many rival solutions to this problem of political authority have been offered by contemporary and recent philosophers but none has obtained wide acceptance. The current debate takes no cognisance of George Berkeley’s ‘Passive Obedience’, in which he defends the exceptionless duty of not (...) using force to resist the state and offers a rule-consequentialist account of morality which indicates an explanation of political authority as grounded in the social connectedness of human beings. I expound, criticise and develop Berkeley’s explanation to provide a promising solution to the problem of political authority. The solution impugns the political authority of all existing states as well as the duty of passive obedience. (shrink)

Ziel des Beitrages ist, die Bedeutung der Mysterien für das Denken des jungen Nietzsche, der unauffällig, aber dezidiert die Kernbegriffe seines Philosophierens - das Apollinische und das Dionysische, die Tragödie, die ästhetische Rechtfertigung der Welt - mit einer 'Geheimlehre' vervindet, auszuloten. Eine textnah Interpretation seiner Aussagen zur apollinischen bzw. dionysischen Mysterienordung zeigt, dass die tragische griechische Kultur im Mysterienvorgang als kultischem un institutionellem Geschehen begründet ist. Aus Nietzsches Analyse dieser die Metaphysik des Willens exemplarisch zum Ausdruck bringenden Kultur geht hervor, (...) dass ohne Mysterien der Wille sich nicht optimal entfalten kann. Diese Einsicht überträgt Nietzsche auch in die Sprache seines Philosophierens.The aim of the article is to fathom the meaning of mystery cults in Nietzsche's early thinking. in a discreet manner, he associates the key concepts of his philosophy - the Apollonian and the Dionysian, the tragedy, the aesthetic justification of the world - with a 'secret doctrine'. A close reading of his writings on the Apollonian and Dionysian 'mystery order' shows that the tragic Greek culture is founded on the mysteris as cultic and institutional happenings. Nietzsche's analysis of this culture, which gives expression to the metaphysics of the will in an exemplary fashion, reveals that without mystery cults the will cannot unfold itself optimally . Nietzsche translates this insight also into the language of his philosophy. (shrink)