Insulin is a member of a family of hormones, growth factors and neuropeptides which are found in both vertebrates and invertebrates. A common ‘insulin fold’ is probably adopted by all family members. Although the specificities of receptor binding are different, there is possibility of co‐evolution of polypeptides and their receptors.

If philosophical moral reflection tends to improve moral behaviour, one might expect that professional ethicists will, on average, behave morally better than non-ethicists. One potential source of insight into the moral behaviour of ethicists is philosophers' opinions about ethicists' behaviour. At the 2007 Pacific Division meeting of the American Philosophical Association, we used chocolate to entice 277 passers-by to complete anonymous questionnaires without their knowing the topic of those questionnaires in advance. Version I of the questionnaire asked respondents to compare, (...) in general, the moral behaviour of ethicists to that of philosophers not specializing in ethics and to non-academics of similar social background. Version II asked respondents similar questions about the moral behaviour of the ethics specialist in their department whose name comes next in alphabetical order after their own. Both versions asked control questions about specialists in metaphysics and epistemology. The majority of respondents expressed the view that ethicists do not, on average, behave better than non-ethicists. Whereas ethicists tended to avoid saying that ethicists behave worse than non-ethicists, non-ethicists expressed that pessimistic view about as often as they expressed the view that ethicists behave better. (shrink)

The Warnock Committee decided not to sanction artificial insemination by donor (AID) and in vitro fertilisation (IVF) for single heterosexual women or for lesbian women on the grounds that it is better for children to be born into a two-parent heterosexual family. From an examination of the effects on children of growing up in fatherless heterosexual and lesbian families, this paper questions that assumption.

Like every major new technology, genetic engineering is affecting the hopes and fears of many people. The risks involved are perceived differently by different groups. One group regards genetic engineering as a simple extension of older techniques with no special risks, e.g. traditional breeding. This conservative denial of special risks is confronted with a different kind of conservatism from a group which, in the name of the preservation of nature, opposes any kind of genetic engineering. A third group, rooted in (...) the liberal tradition, is prepared to accept the risks of genetic engineering as long as they are outweighed by prospective benefits. The liberal as well as the two conservative approaches, however, face serious difficulties in trying to develop a sound ethical argument concerning genetic engineering. In order to avoid these difficulties, an ethical approach focused on paradigmatic examples of good and evil is proposed. Such examples constitute rules of moral description, much as standards of measurement constitute rules of physical description. These rules are elaborated and interpreted in processes of social learning. In the present state of development of genetic engineering, such social learning requires appropriate institutional procedures. (shrink)

The objectives of this study were to develop a high-density chromosome bin map of homoeologous group 7 in hexaploid wheat, to identify gene distribution in these chromosomes, and to perform comparative studies of wheat with rice and barley. We mapped 2148 loci from 919 EST clones onto group 7 chromosomes of wheat. In the majority of cases the numbers of loci were significantly lower in the centromeric regions and tended to increase in the distal regions. The level of duplicated loci (...) in this group was 24% with most of these loci being localized toward the distal regions. One hundred nineteen EST probes that hybridized to three fragments and mapped to the three group 7 chromosomes were designated landmark probes and were used to construct a consensus homoeologous group 7 map. An additional 49 probes that mapped to 7AS, 7DS, and the ancestral translocated segment involving 7BS also were designated landmarks. Landmark probe orders and comparative maps of wheat, rice, and barley were produced on the basis of corresponding rice BAC/PAC and genetic markers that mapped on chromosomes 6 and 8 of rice. Identification of landmark ESTs and development of consensus maps may provide a framework of conserved coding regions predating the evolution of wheat genomes. (shrink)

I begin by considering various leadership aetiologies, wherein someone comes to obtain the various rights and obligations associated with the status function of a leader. Searle imagines two possibilities. First, someone comes to be a leader by way of established (e.g. democratic) constitutive rules or procedures. Second, someone might simply be declared a leader if they already wield sufficient coercive, non-deontological power. The deontological power associated with the status function of a leader is different from the antecedently existing coercive power (...) in that the former works, not under the force of threat, but by way of the imposition of rights and obligations. I consider a third leadership aetiology based on charismatic power. The possibility of charismatic power, in turn, recommends a normative, aesthetic source that cannot be reduced to either deontological power or coercive power. I begin by looking, in Sections 1 and 2, at examples which gesture towards the plausibility of aesthetic norms as a constituent of some status functions. Using a largely Humean account of the aesthetic (Section 3) in Sections 4 and 5, I argue that aesthetic evaluations have the right formal properties to underlie a status function. In particular, they are suitably epistemically objective, and they can provide desire-independent reasons for action. Finally, in Section 6, I argue aesthetic norms that are necessarily unprincipled, decisively account for a class of status functions which resist articulation in terms of explicitly codified rights and obligations. (shrink)

John Searle (1932-) is one of the most famous living American philosophers. A pupil of J. L. Austin at Oxford in the 1950s, he is currently Mills Professor of the Philosophy of Mind and Language at the University of California, Berkeley. In 1995 John Searle published "The Construction of Social Reality", a text which not only promises to disclose the institutional backdrop against which speech takes place, but initiate a new 'philosophy of society'. Since then "The Construction of Social Reality" (...) has been subject to a flurry of criticism. While many of Searle's interlocutors share the sense that the text marks an important breakthrough, he has time and again accused critics of misunderstanding his claims. Despite Searle's characteristic crispness and clarity there remains some confusion, among both philosophers and sociologists, regarding the significance of his proposals. This book traces some of the high points of this dialogue, leveraging Searle's own clarifications to propose a new way of understanding the text. In particular, Joshua Rust looks to Max Weber in suggesting that Searle has articulated an ideal type. In locating The Construction of Social Reality under the umbrella of one of sociology's founding fathers, this book not only makes Searle's text more accessible to the readers in the social sciences, but presents Max Weber as a thinker worthy of philosophical reconsideration. Moreover, the recharacterization of Searle's claims in terms of the ideal type helps facilitate a comparison between Searle and other social theorists such as Talcott Parsons. (shrink)

We argued in Part 1 of this series that because all living systems are extremely far‐from‐equilibrium dynamic confections of matter, they must necessarily be driven to that state by the conversion of chemically specific external disequilibria into specific internal disequilibria. Such conversions require task‐specific macromolecular engines. We here argue that the same is not only true of life at its emergence; it is the enabling cause of that emergence; although here the external driving disequilibria, and the conversion engines needed must (...) have been abiotic. We argue further that the initial step in life's emergence can only create an extremely simple non‐equilibrium “seed” from which all the complexity of life must then develop. We assert that this complexity develops incrementally and progressively, each step tested for value added “in flight.” And we make the case that only the submarine alkaline hydrothermal vent (AHV) model has the potential to satisfy these requirements. (shrink)

Unfortunately, few substantial works by the "new wave" of Eastern European philosophers have yet appeared in widely read languages. Those who are interested in a glimpse into these developments will therefore welcome this international anthology devoted to the topic of socialist humanism. Such authors as Schaff, Bloch, Petrovic, and Korac are represented, as well as Western writers such as Goldmann, Marcuse, Rubel, and Russell, whose "In Praise of Idleness" was apparently thought relevant to this subject. Unfortunately, the brevity of these (...) contributions forces the authors to limit the penetration of their remarks, so that in some cases one gets an impression of superficiality which is not fair to them. But until their major works are translated, or until we all learn Serbo-Croatian and Polish, this is the best we can do, and it gives evidence that very interesting themes indeed are being discussed these days behind the rusting Iron Curtain. The titles of the sections of the book, which give a rough idea of the matters with which the essays deal, are On Humanism, On Man, On Freedom, On Alienation, and On Practice.—J. J. (shrink)

In True Detective, the character of Rust Cohle is remarkable in giving voice to pessimism. Cohle says: "Time is a flat circle". This is Friedrich Nietzsche's doctrine of eternal recurrence, as depicted in The Gay Science and Thus Spoke Zarathustra. Cohle expresses this idea in a pessimistic mood and it is meant to magnify the absurdity of life by declaring its endless repetition. Schopenhauer was an early influence on Nietzsche, and they agreed on certain basic things, including the primacy (...) of a driving will, which generates perpetual conflict with no ultimate resolution and no salvation. Nietzsche's book, Thus Spoke Zarathustra, provides a dramatic narrative depicting the task of life‐affirmation in the face of eternal recurrence. The portrayal of eternal recurrence in True Detective is not in the spirit of Nietzsche's conception. It is more akin to Schopenhauer's response. Nietzsche finds a way to overcome pessimism by affirming life because of its tragic limits. (shrink)

While developments of a shared intellectual tradition, the enactivist approach and the organizational account proffer importantly different accounts of organismic normativity. Where enactivists tend to follow Hans Jonas, Andres Weber, and Francisco Varela in grounding intrinsic affordance norms in existential concern, organizational theorists such as Alvaro Moreno, Matteo Mossio, and Leonardo Bich seek a more deflationary account of these normative phenomena. Critiques directed at both of these accounts of organismic normativity motivate the introduction of the precedential account of organismic normativity, (...) which I nevertheless locate within the enactivist approach, broadly construed. After detailing empirical evidence that would seem to vindicate the precedential account, I explore some of its implications. (shrink)

We review and present a new meta‐analysis of research suggesting that ethicists in the United States appear to behave no morally better overall than do non‐ethicist professors. Measures include: returning library books, peer evaluation of overall moral behavior, voting participation, courteous and discourteous behavior at conferences, replying to student emails, paying conference registration fees and disciplinary society dues, staying in touch with one's mother, charitable giving, organ and blood donation, vegetarianism, and honesty in responding to survey questions. One multi‐measure study (...) found ethicists tending to embrace more stringent moral views, especially about meat eating and charitable donation. The same multi‐measure study found ethicists and other professors to show similarly small‐to‐medium correlations between their expressed normative attitudes and their self‐reported or directly measured behavior. (shrink)

Artificial intelligence (AI) and machine learning (ML) are increasingly integrated into the functioning of physical and digital products, creating unprecedented opportunities for interaction and functionality. However, there is a challenge for designers to ideate within this creative landscape, balancing the possibilities of technology with human interactional concerns. We investigate techniques for exploring and reflecting on the interactional affordances, the unique relational possibilities, and the wider social implications of AI systems. We introduced into an interaction design course (_n_ = 100) nine (...) ‘AI exercises’ that draw on more than human design, responsible AI, and speculative enactment to create experiential engagements around AI interaction design. We find that exercises around metaphors and enactments make questions of training and learning, privacy and consent, autonomy and agency more tangible, and thereby help students be more reflective and responsible on how to design with AI and its complex properties in both their design process and outcomes. (shrink)

Do professional ethicists behave any morally better than other professors do? Do they show any greater consistency between their normative attitudes and their behavior? In response to a survey question, a large majority of professors (83 percent of ethicists, 83 percent of nonethicist philosophers, and 85 percent of nonphilosophers) expressed the view that “not consistently responding to student e‐mails” is morally bad. A similarly large majority of professors claimed to respond to at least 95 percent of student e‐mails. These professors, (...) and others, were sent three e‐mails designed to look like queries from students. Ethicists’ e‐mail response rates were not significantly different from the other two groups’. Expressed normative view correlated with self‐estimated rate of e‐mail responsiveness, especially among the ethicists. Empirically measured e‐mail responsiveness, however, was at best weakly correlated with self‐estimated e‐mail responsiveness; and professors’ expressed normative attitude was not significantly correlated with empirically measured e‐mail responsiveness for any of the three groups. (shrink)

ABSTRACT Since the 1970s there has been a significant paradigm shift in psychology away from behaviourism and towards cognitive psychology. Indeed a recent survey discovered that by 1983 more than half American psychologists were describing their approaches as cognitive. However, while behaviourism has had an identifiable philosophical ‘line’ in positivism, reductionism and the hypothetico‐deductive model, such a framework has been noticeably lacking from cognitive psychology. A view of cognitive psychology based on functionalism and ideas from systems analysis is put forward.

Do philosophy professors specializing in ethics behave, on average, any morally better than do other professors? If not, do they at least behave more consistently with their expressed values? These questions have never been systematically studied. We examine the self-reported moral attitudes and moral behavior of 198 ethics professors, 208 non-ethicist philosophers, and 167 professors in departments other than philosophy on eight moral issues: academic society membership, voting, staying in touch with one's mother, vegetarianism, organ and blood donation, responsiveness to (...) student emails, charitable giving, and honesty in responding to survey questionnaires. On some issues, we also had direct behavioral measures that we could compare with the self-reports. Ethicists expressed somewhat more stringent normative attitudes on some issues, such as vegetarianism and charitable donation. However, on no issue did ethicists show unequivocally better behavior than the two comparison groups. Our findings on attitude-behavior consistency were mixed: ethicists showed the strongest relationship between behavior and expressed moral attitude regarding voting but the weakest regarding charitable donation. We discuss implications for several models of the relationship between philosophical reflection and real-world moral behavior. (shrink)

If philosophical moral reflection improves moral behavior, one might expect ethics professors to behave morally better than socially similar non-ethicists. Under the assumption that forms of political engagement such as voting have moral worth, we looked at the rate at which a sample of professional ethicists—and political philosophers as a subgroup of ethicists—voted in eight years’ worth of elections. We compared ethicists’ and political philosophers’ voting rates with the voting rates of three other groups: philosophers not specializing in ethics, political (...) scientists, and a comparison group of professors specializing in neither philosophy nor political science. All groups voted at about the same rate, except for the political scientists, who voted about 10–15% more often. On the face of it, this finding conflicts with the expectation that ethicists will behave more responsibly than non-ethicists. (shrink)

While in the beginning of the environmental debate, conflicts over environmental and technological issues had primarily been understood in terms of ‘‘risk’’, over the past two decades the relevance of ignorance, or nonknowledge, was emphasized. Referring to this shift of attention to nonknowledge the article presents two main findings: first, that in debates on what is not known and how to appraise it different and partly conflicting epistemic cultures of nonknowledge can be discerned and, second, that drawing attention to nonknowledge (...) in technology conflicts results in significant institutional effects and new constellations of actors in public debates. To illustrate and substantiate this political dynamics of nonknowledge we draw upon examples from the areas of agri-biotechnology and mobile phoning. In a first step, we develop in greater detail the concept of scientific cultures of nonknowledge and identify three such cultures involved in the social conflicts within the two areas. Subsequently, we analyze the specific dynamics of the politicisation of nonknowledge looking at the variety of actors involved and the pluralisation of perceptions and evaluations of what is not known. Then, we point out some of the institutional reactions to the political and cultural dynamics of scientific nonknowledge. We argue that the equal recognition of the diverse cultures of nonknowledge is a key prerequisite for socially legitimate and ‘‘robust’’ decision-making under conditions of politicised scientific nonknowledge. (shrink)

Key elements of John Searle’s articulation of the Standard Model of Social Ontology can be found within Max Weber’s ideal type of legal-rational authority. However, the fact that, for Weber, legal-rational authority is just one of three types of legitimate authority, along with traditional and charismatic authority, suggests limitations to the Standard Model’s scope of applicability. Where Searle takes himself to have provided an account of “the structure of human civilization,” Weber’s taxonomy suggests that Searle has only given us an (...) account of a way of being a civilization. This understanding of traditional authority also reveals why the Standard Model misconstrues the structure of ordinary, informal statuses, such as friendship. (shrink)

If philosophical moral reflection tends to promote moral behavior, one might think that professional ethicists would behave morally better than do socially comparable non-ethicists. We examined three types of courteous and discourteous behavior at American Philosophical Association conferences: talking audibly while the speaker is talking (versus remaining silent), allowing the door to slam shut while entering or exiting mid-session (versus attempting to close the door quietly), and leaving behind clutter at the end of a session (versus leaving one's seat tidy). (...) By these three measures, audiences in ethics sessions did not appear to behave any more courteously than did audiences in non-ethics sessions. However, audiences in environmental ethics sessions did appear to leave behind less trash. (shrink)

Do professional ethicists behave any morally better than other professors do? Do they show any greater consistency between their normative attitudes and their behavior? In response to a survey question, a large majority of professors (83 percent of ethicists, 83 percent of nonethicist philosophers, and 85 percent of nonphilosophers) expressed the view that “not consistently responding to student e-mails” is morally bad. A similarly large majority of professors claimed to respond to at least 95 percent of student e-mails. These professors, (...) and others, were sent three e-mails designed to look like queries from students. Ethicists’ e-mail response rates were not significantly different from the other two groups’. Expressed normative view correlated with self-estimated rate of e-mail responsiveness, especially among the ethicists. Empirically measured e-mail responsiveness, however, was at best weakly correlated with self-estimated e-mail responsiveness; and professors’ expressed normative attitude was not significantly correlated with empirically measured e-mail responsiveness for any of the three groups. (shrink)

Consequence is at the heart of logic, and an account of consequence offers a vital tool in the evaluation of arguments. This text presents what the authors term as 'logical pluralism' arguing that the notion of logical consequence doesn't pin down one deductive consequence relation; it allows for many of them.

This paper aims to uncover the explanatory profile of an idealized version of Karl Ernst von Baer’s notion of individuation, wherein the special develops from the general. First, because such sequences can only be exemplified by a multiplicity of causally-related events, they should be seen as the topics of historical why-questions, rather than initial condition why-questions. Second, because historical why-questions concern the diachronic unity or genidentity of the events under consideration, I argue that the von Baerian pattern elicits a distinctive (...) response to such questions, wherein we are inclined to simultaneously affirm and reject the temporal unity of these events. I buttress this claim by considering non-biological expressions of the von Baerian principle, drawn from institutional history and literature. In the second half of the paper, I consider the implications of my findings for ontogenetic and phylogenetic sequences. I argue that the explanatory profile of von Baer’s principle neatly describes the distinctive speciation events that characterize deep metazoan phylogeny, as described by Stuart Newman. I also argue that parallel considerations should move us to accept a sense in which ontogenetic stages are not diachronically unified. (shrink)

There is growing political pressure for farmers to use more sustainable agricultural practices to protect people and the planet. The farming press could encourage farmers to adopt sustainable practices through its ability to manipulate discourse and spread awareness by changing the salience of issues or framing topics in specific ways. We sought to understand how the UK farming press framed sustainable agricultural practices and how the salience of these practices changed over time. We combined a media content analysis of the (...) farming press alongside 60 qualitative interviews with farmers and agricultural advisors to understand whether the farming press influenced farmers to try more sustainable practices. Salience of sustainable agricultural practices grew between 2009 and 2020. Many of the practices studied were framed by the press around economic and agronomic aspects, and farmer respondents said the most common reasons for trying sustainable agricultural practices were for economic and agronomic reasons. The farming press tended to use more positive rather than negative tones when covering sustainable agricultural practices. Respondents used the farming press as a source of information, though many did not fully trust these outlets as they believed the farming press were mouthpieces for agribusinesses. Whilst a minority of farmers stated they were motivated to try a new sustainable agricultural practice after learning about it in the farming press, this was rare. Instead, the farming press was used by respondents to raise their awareness about wider agricultural topics. We reflect on the role and power given to agribusinesses by the farming press and what this means for agricultural sustainability. (shrink)

Technical artifacts do not seem particularly continuous with institutional statuses. If statuses are defined in terms of their constitutive rules, as Searle maintains, then disassociation is always possible – someone or something can satisfy those rules without being able to realize the functional effects that are associated with that status. The gap between technical artifacts and Searlean statuses suggests the possibility of an additional social kind, which I call, following Muhammad Ali Khalidi, a ‘real social kind’. However, the placement of (...) real social kinds between technical artifacts and statuses recommends a reconfiguration of Khalidi’s most abstract characterization of the notion. This reconfiguration also lends support to his surprising claim that money is a real social kind. (shrink)

Providing an original and systematic treatment of foundational issues in philosophy of religion, J. L. Schellenberg's new book addresses the structure of..

What happens when someone acts? A familiar answer goes like this. There is something that the agent wants, and there is an action that he believes conducive to its attainment. His desire for the end, and his belief in the action as a means, justify taking the action, and they jointly cause an intention to take it, which in turn causes the corresponding movements of the agent's body. I think that the standard story is flawed in several respects. The flaw (...) that will concern me in this paper is that the story fails to include an agent-or, more precisely, fails to cast the agent in his proper role. (shrink)

This paper is an investigation into the possibility of institutional agency and proceeds via the elaboration of two, nested claims. First, if genuine agency is attributable to certain social institutions, it would not be the full-blown, intentional agency that characterizes human activity, but would rather fall under a minimal modality of agency. Moreover, since enactivists aim to articulate minimal conceptions of agency that are applicable across the sphere of the living, this suggests that such accounts of minimal agency might additionally (...) be brought to bear onto some institutions. The second claim concerns which of two ideally typical enactivist accounts of minimal agency can more promisingly be applied to our institutions. Where some enactivists endorse a Jonasian account of minimal agency, which stresses a protentive, forward-looking orientation to a self-persistence goal, other enactivists apply a retentive ideal type of minimal agency, the norms of which are founded on a backward-looking responsiveness to precedent. By way of a critical analysis of structural functionalism, I argue that the retentive approach better explains the kind of agency that would be expressed by some institutions. I also claim that some philosophers, including Christian List, Philip Pettit and Ronald Dworkin, have independently come to the conclusion that institutional agency is retentive agency. (shrink)

Introduction -- Fundamental ontology : external realism and scientific naturalism -- Consciousness and materialist theories of mind -- Intentional mental states -- Reason and action -- From acts to speech acts : the intention to communicate -- From sounds to words : the intention to represent -- On the meaning of meaning : critical remarks -- The construction of social reality -- Topics concerning institutional reality : reasons, language, politics, and the background.

In lieu of an abstract, here is a brief excerpt of the content:A Literary Common GroundLee Rust BrownLet me make note of a few things that have occurred to me during this conference. Some of these will be observations; some will be practical inferences. One of them, though, involves the crossing of an expectation, or maybe a fear, I had brought with me to Minneapolis. Since this has to do with the whole tone of the conference, we might as (...) well begin with it.It, of course, was the question of the polemical nature of this gathering. Would this conference be diagnostic and denunciatory in nature, or would it seek to start something truly new? Certainly we all feel the need of something new—not new, either, in the sense that movements or ideological positions claim to be new, but in the sense of a fresh gathering of common attention in the place where literature is, the place where each of us who loves literature already goes alone. This would be a possibility for something original rather than just another novelty—which makes the question of polemics all the more urgent. An association that founded itself in complaint would be only one more identity-group making a virtue out of its grudge. And the grudge, in that case, would have been a sad reflex of feeling superseded and powerless.But where have the polemics against current orthodoxies been? I am delighted not to have heard them in any strenuous capacity. Even their relative absence hasn’t commanded any extended attention, and that may be an even more telling point. I take this to be partly the result of foresight and good sense. But the clean air here has been more than a reward for our mutual constraint. Instead, it seems evidence of the fact [End Page 193] that, when literature occupies our attention, there is no need for self-defense. Justice, or justification, happens by itself when we “do our own work,” as Socrates recommended.What is our own work, then? This association has made a point, it seems, of declining to prescribe what it should be. The only thing we are absolutely sure of is that its subject is literature, and that its standards and rewards should be of a literary nature. From there the field opens up—and this conference has succeeded in keeping it open in some very concrete ways.Let’s think briefly about the two panels we attended yesterday. The morning panel on “Intellectual Craftsmanship” seemed unified in its concern with the disciplined ways by which we commit ourselves to literary experience. Literature itself, as well as what we do with it, teaches us this discipline, which is “aesthetic” in every sense of that word. Roger Shattuck set the tone when he described the discipline of reading as an issue of preparation and assimilation on the one hand, and as a kind of complete perceptual openness on the other. Such openness, in our normal experience, allows us to be surprised, to see actual things, perhaps, instead of their institutional categories. But literature also requires that we craft our receptivity. The surprises we prepare ourselves to undergo are achieved breakthroughs, which makes them no less unpredictable but all the more deeply affecting.Criticism cultivates such surprising experience. (I think experience is the crucial word, by the way, since everyone on that first panel seemed to be devoted to a kind of free empiricism.) The spectacular moments of visionary power that Robert Alter isolated in Dickens are places that startle and disturb us—and we track our own surprise, and intensify it, when we look closely at how those dark places of power emerge from Dickens’s refiguring of a world where darkness otherwise tends toward an entirely unredeemable opacity. We have to read “synesthetically,” as Shattuck says, “with both eyes open,” to let ourselves be for a moment blinded by such literary places.Once again, the discipline of reading—devotedly and resistantly—frees us for the achieved experience. Slowing down, in Sven Birkerts’s sense of “retardation and deceleration,” is precisely a matter of stepping into a field of experience shaped (or, in an auditory sense, fostered and conserved) by the special demands of literature. It... (shrink)

It has been shown that when participants are asked to make sensibility judgments on sentences that describe a transfer of an object toward or away from their body, they are faster to respond when the response requires a movement in the same direction as the transfer described in the sentence. This phenomenon is known as the action compatibility effect. This study investigates whether the ACE exists for volunteers with Alzheimer's disease, whether the ACE can facilitate language comprehension, and also whether (...) the ACE can still be produced if the order of the two events is inverted, that is, whether overt movement can prime comprehension of transfer sentences. In Study 1, participants with AD, younger, and older adults were tested on an adaptation of the ACE Paradigm. In Study 2, the same paradigm was modified to include an arm movement that participants had to perform prior to sentence exposure on screen. In Study 1, young, older adults, and individuals with AD were faster to respond when the direction of the response movement matched the directionality implied by the sentence. In Study 2, no traditional ACE was found; participants were faster when the direction of the movement immediately preceding the sentence matched the directionality of the sentence. It was found that compatibility effects generated a relative advantage, that transfer schemata are easier to process, and that an ACE-like effect can be the result of mutual priming between language and movement. Results suggested preservation in AD of the neural systems for action engaged during language comprehension, and conditions under which comprehension in AD can be facilitated in real life may be identified. (shrink)

Abstract I argue that meaning in life is importantly influenced by bioloical ties. More specifically, I maintain that knowing one's relatives and especially one's parents provides a kind of self-knowledge that is of irreplaceable value in the life-task of identity formation. These claims lead me to the conclusion that it is immoral to create children with the intention that they be alienated from their bioloical relatives?for example, by donor conception.