Results for 'Cesar Palacios-Gonzalez'

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  1. Reproductive genome editing interventions are therapeutic, sometimes.César Palacios-González - 2021 - Bioethics 35 (6):557-562.
    In this paper I argue that some human reproductive genome editing interventions can be therapeutic in nature, and thus that it is false that all such interventions just create healthy individuals. I do this by showing that the conditions established by a therapy definition are met by certain reproductive genome editing interventions. I then defend this position against two objections: (a) reproductive genome editing interventions do not attain one of the two conditions for something to be a therapy, and (b) (...)
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  2. Multiplex parenting: IVG and the generations to come.César Palacios-González, John Harris & Giuseppe Testa - 2014 - Journal of Medical Ethics 40 (11):752-758.
    Recent breakthroughs in stem cell differentiation and reprogramming suggest that functional human gametes could soon be created in vitro. While the ethical debate on the uses of in vitro generated gametes (IVG) was originally constrained by the fact that they could be derived only from embryonic stem cell lines, the advent of somatic cell reprogramming, with the possibility to easily derive human induced pluripotent stem cells from any individual, affords now a major leap in the feasibility of IVG derivation and (...)
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  3. Mitochondrial Replacement Techniques and Mexico’s Rule of Law: On the Legality of the First Maternal Spindle Transfer Case.César Palacios-González - 2017 - Journal of Law and the Biosciences 4 (1):50–69.
    News about the first baby born after a mitochondrial replacement technique (MRT; specifically maternal spindle transfer) broke on September 27, 2016 and, in a matter of hours, went global. Of special interest was the fact that the mitochondrial replacement procedure happened in Mexico. One of the scientists behind this world first was quoted as having said that he and his team went to Mexico to carry out the procedure because, in Mexico, there are no rules. In this paper, we explore (...)
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  4.  48
    Are there moral differences between maternal spindle transfer and pronuclear transfer?César Palacios-González - 2017 - Medicine, Health Care and Philosophy 20 (4):503-511.
    This paper examines whether there are moral differences between the mitochondrial replacement techniques that have been recently developed in order to help women afflicted by mitochondrial DNA diseases to have genetically related children absent such conditions: maternal spindle transfer and pronuclear transfer. Firstly, it examines whether there is a moral difference between MST and PNT in terms of the divide between somatic interventions and germline interventions. Secondly, it considers whether PNT and MST are morally distinct under a therapy/creation optic. Finally, (...)
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  5.  32
    Mitochondrial replacement techniques: egg donation, genealogy and eugenics.César Palacios-González - 2016 - Monash Bioethics Review 34 (1):37-51.
    Several objections against the morality of researching or employing mitochondrial replacement techniques have been advanced recently. In this paper, I examine three of these objections and show that they are found wanting. First I examine whether mitochondrial replacement techniques, research and clinical practice, should not be carried out because of possible harms to egg donors. Next I assess whether mitochondrial replacement techniques should be banned because they could affect the study of genealogical ancestry. Finally, I examine the claim that mitochondrial (...)
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  6. Resource Allocation, Treatment, Disclosure, and Mitochondrial Replacement Techniques: Some Comments on de Melo-Martin and Harris.César Palacios-gonzález - 2017 - Cambridge Quarterly of Healthcare Ethics 26 (2):278-287.
    Some Comments on de Melo-Martin and Harris.
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  7.  40
    Human dignity and the creation of human–nonhuman chimeras.César Palacios-González - 2015 - Medicine, Health Care and Philosophy 18 (4):487-499.
    In this work I present a detailed critique of the dignity-related arguments that have been advanced against the creation of human–nonhuman chimeras that could possess human-like mental capacities. My main claim is that the arguments so far advanced are incapable of grounding a principled objection against the creation of such creatures. I conclude that these arguments have one, or more, of the following problems: they confuse the ethical assessment of the creation of chimeras with the ethical assessment of how such (...)
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  8.  52
    Does egg donation for mitochondrial replacement techniques generate parental responsibilities?César Palacios-González - 2018 - Journal of Medical Ethics 44 (12):817-822.
    Children created through mitochondrial replacement techniques (MRTs) are commonly presented as possessing 50% of their mother’s nuclear DNA, 50% of their father’s nuclear DNA and the mitochondrial DNA of an egg donor. This lab-engineered genetic composition has prompted two questions: Do children who are the product of an MRT procedure have threegeneticparents? And, do MRT egg donors have parental responsibilities for the children created? In this paper, I address the second question and in doing so I also address the first (...)
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  9. Genetic parenthood and causation: An objection to Douglas and Devolder’s modified direct proportionate genetic descent account.César Palacios-González - 2019 - Bioethics 33 (9):1085-1090.
    In a recent publication Tom Douglas and Katrien Devolder have proposed a new account of genetic parenthood, building on the work of Heidi Mertes. Douglas and Devolder’s account aims to solve, among other things, the question of who are the genetic parents of an individual created through somatic cell nuclear transfer (i.e. cloning): (a) the nuclear DNA provider or (b) the progenitors of the nuclear DNA provider. Such a question cannot be answered by simply appealing to the folk account of (...)
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  10. Author's response to peer commentaries: Mexico's rule of law and MRTs.César Palacios-González & María de Jesús Medina-Arellano - 2017 - Journal of Law and the Biosciences 4 (3):623–629.
  11.  37
    The ethics of killing human/great-ape chimeras for their organs: a reply to Shaw et al.César Palacios-González - 2016 - Medicine, Health Care and Philosophy 19 (2):215-225.
    The aim of this paper is to critically examine David Shaw, Wybo Dondorp, and Guido de Wert’s arguments in favour of the procurement of human organs from human/nonhuman-primate chimeras, specifically from great-ape/human chimeras. My main claim is that their arguments fail and are in need of substantial revision. To prove this I first introduce the topic, and then reconstruct Shaw et al.’s position and arguments. Next, I show that Shaw et al.: failed to properly apply the subsidiarity and proportionality principles; (...)
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  12.  22
    Ethical aspects of creating human–nonhuman chimeras capable of human gamete production and human pregnancy.César Palacios-González - 2015 - Monash Bioethics Review 33 (2-3):181-202.
    In this paper I explore some of the moral issues that could emerge from the creation of human–nonhuman chimeras capable of human gamete production and human pregnancy. First I explore whether there is a cogent argument against the creation of HNH-chimeras that could produce human gametes. I conclude that so far there is none, and that in fact there is at least one good moral reason for producing such types of creatures. Afterwards I explore some of the moral problems that (...)
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  13.  49
    Ethics of Mitochondrial Replacement Techniques: A Habermasian Perspective.César Palacios-González - 2016 - Bioethics 31 (1):27-36.
    Jürgen Habermas is regarded as a central bioconservative commentator in the debate on the ethics of human prenatal genetic manipulations. While his main work on this topic, The Future of Human Nature, has been widely examined in regard to his position on prenatal genetic enhancement, his arguments regarding prenatal genetic therapeutic interventions have for the most part been overlooked. In this work I do two things. First, I present the three necessary conditions that Habermas establishes for a prenatal genetic manipulation (...)
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  14. Chimeras intended for human gamete production: an ethical alternative?César Palacios-González - 2017 - Reproductive Biomedicine Online 35 (4):387-390.
    Human eggs for basic, fertility and stem-cell research are in short supply. Many experiments that require their use cannot be carried out at present, and, therefore, the benefits that could emerge from these are either delayed or never materialise. This state of affairs is problematic for scientists and patients worldwide, and it is a matter that needs our attention. Recent advances in chimera research have opened the possibility of creating human/non-human animal chimeras intended for human gamete production (chimeras-IHGP). In this (...)
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  15. Beyond Individual Triage: Regional Allocation of Life-Saving Resources such as Ventilators in Public Health Emergencies.Jonathan Pugh, Dominic Wilkinson, Cesar Palacios-Gonzalez & Julian Savulescu - 2021 - Health Care Analysis 29 (4):263-282.
    In the first wave of the COVID-19 pandemic, healthcare workers in some countries were forced to make distressing triaging decisions about which individual patients should receive potentially life-saving treatment. Much of the ethical discussion prompted by the pandemic has concerned which moral principles should ground our response to these individual triage questions. In this paper we aim to broaden the scope of this discussion by considering the ethics of broader structural allocation decisions raised by the COVID-19 pandemic. More specifically, we (...)
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  16.  40
    ‘Yes’ to mitochondrial replacement techniques and lesbian motherhood: a reply to Françoise Baylis.César Palacios-González & Giulia Cavaliere - 2019 - Journal of Medical Ethics 45 (4):280-281.
    In a recent paper – Lesbian motherhood and mitochondrial replacement techniques: reproductive freedom and genetic kinship – we argued that lesbian couples who wish to have children who are genetically related to both of them should be allowed access to mitochondrial replacement techniques. Françoise Baylis wrote a reply to our paper –‘No’ to lesbian motherhood using human nuclear genome transfer– where she challenges our arguments on the use of MRTs by lesbian couples, and on MRTs more generally. In this reply (...)
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  17. Ethical heuristics for pandemic allocation of ventilators across hospitals.César Palacios-González, Jonathan Pugh, Dominic Wilkinson & Julian Savulescu - 2022 - Developing World Bioethics 22 (1):34-43.
    In response to the COVID‐19 pandemic philosophers and governments have proposed scarce resource allocation guidelines. Their purpose is to advise healthcare professionals on how to ethically allocate scarce medical resources. One challenging feature of the pandemic has been the large numbers of patients needing mechanical ventilatory support. Guidelines have paradigmatically focused on the question of what doctors should do if they have fewer ventilators than patients who need respiratory support: which patient should get the ventilator? There is, however, an important (...)
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  18.  43
    Artificial Intelligence.David R. Lawrence, César Palacios-gonzález & John Harris - 2016 - Cambridge Quarterly of Healthcare Ethics 25 (2):250-261.
  19. Mexico and mitochondrial replacement techniques: what a mess.César Palacios-González - 2018 - British Medical Bulletin 128.
    Abstract Background The first live birth following the use of a new reproductive technique, maternal spindle transfer (MST), which is a mitochondrial replacement technique (MRT), was accomplished by dividing the execution of the MST procedure between two countries, the USA and Mexico. This was done in order to avoid US legal restrictions on this technique. -/- Sources of data Academic articles, news articles, documents obtained through freedom of information requests, laws, regulations and national reports. -/- Areas of agreement MRTs are (...)
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  20. Mitochondrial Replacement Techniques: Genetic Relatedness, Gender Implications, and Justice.César Palacios-González & Tetsuya Ishii - 2017 - Gender and the Genome 1 (4):1-6.
    In 2015 the United Kingdom (UK) became the first nation to legalize egg and zygotic nuclear transfer procedures using mitochondrial replacement techniques (MRTs) to prevent the maternal transmission of serious mitochondrial DNA diseases to offspring. These techniques are a form of human germline genetic modification and can happen intentionally if female embryos are selected during the MRT clinical process, either through sperm selection or preimplantation genetic diagnosis (PGD). In the same year, an MRT was performed by a United States (U.S.)-based (...)
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  21.  75
    Lesbian motherhood and mitochondrial replacement techniques: reproductive freedom and genetic kinship.Giulia Cavaliere & César Palacios-González - 2018 - Journal of Medical Ethics 44 (12):835-842.
    In this paper, we argue that lesbian couples who wish to have children who are genetically related to both of them should be allowed access to mitochondrial replacement techniques. First, we provide a brief explanation of mitochondrial diseases and MRTs. We then present the reasons why MRTs are not, by nature, therapeutic. The upshot of the view that MRTs are non-therapeutic techniques is that their therapeutic potential cannot be invoked for restricting their use only to those cases where a mitochondrial (...)
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  22.  20
    Enhancing Sisyphus.César Palacios-González & David R. Lawrence - 2015 - American Journal of Bioethics Neuroscience 6 (1):26-27.
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  23.  33
    The ethics of clinical photography and social media.César Palacios-González - 2015 - Medicine, Health Care and Philosophy 18 (1):63-70.
    Clinical photography is an important tool for medical practice, training and research. While in the past clinical pictures were confined to the stringent controls of surgeries and hospitals technological advances have made possible to take pictures and share them through the internet with only a few clicks. Confronted with this possibility I explore if a case could be made for using clinical photography in tandem with social media. In order to do this I explore: if patient’s informed consent is required (...)
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  24.  5
    Epilepsy, Decisional Vulnerability, and the Nature of Predictive Brain Implants.César Palacios-González - 2015 - American Journal of Bioethics Neuroscience 6 (4):18-19.
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  25.  6
    Genealogical obscurement: mitochondrial replacement techniques and genealogical research.César Palacios-González - forthcoming - Journal of Medical Ethics.
    Mitochondrial replacement techniques (MRTs) are a new group of biotechnologies that aim to aid women whose eggs have disease-causing deleteriously mutated mitochondria to have genetically related healthy children. These techniques have also been used to aid women with poor oocyte quality and poor embryonic development, to have genetically related children. Remarkably, MRTs create humans with DNA from three sources: nuclear DNA from the intending mother and father, and mitochondrial DNA from the egg donor. In a recent publication Françoise Baylis argued (...)
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  26.  33
    Substance over style: is there something wrong with abandoning the white coat?César Palacios-González & David R. Lawrence - 2015 - Journal of Medical Ethics 41 (6):433-436.
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  27.  26
    An Argument for the Intersectional Education of Those Working in International Humanitarian Medical Nongovernmental Organizations.Adriana Clavel-Vazquez & César Palacios-González - 2019 - American Journal of Bioethics 19 (2):42-44.
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  28.  63
    Mitochondrial Replacement Techniques, Scientific Tourism, and the Global Politics of Science.Sarah Chan, César Palacios-González & María De Jesús Medina Arellano - 2017 - Hastings Center Report 47 (5):7-9.
    The United Kingdom is the first and so far only country to pass explicit legislation allowing for the licensed use of the new reproductive technology known as mitochondrial replacement therapy. The techniques used in this technology may prevent the transmission of mitochondrial DNA diseases, but they are controversial because they involve the manipulation of oocytes or embryos and the transfer of genetic material. Some commentators have even suggested that MRT constitutes germline genome modification. All eyes were on the United Kingdom (...)
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  29.  3
    Héctor Velázquez: ¿Qué es la naturaleza? Introducción filosófica a la historia de la ciencia, México: Porrua 2007, 279 pp. [REVIEW]César Palacios González - 2013 - Tópicos: Revista de Filosofía 37 (1):223-225.
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  30.  91
    Ethical challenges during the COVID-19 pandemic: Perspectives of nursing students.Domingo Palacios-Ceña, Juan Francisco Velarde-García, Marta Mas Espejo, Raquel González-Hervías, Beatriz Álvarez-Embarba, Marta Rodríguez-García, Oscar Oliva-Fernández, Pilar González-Sanz, Paloma Moro-López-Menchero, César Fernández-de-las-Peñas & Jose Miguel Cachón-Pérez - 2022 - Nursing Ethics 29 (2):264-279.
    Background:The first wave of the COVID-19 pandemic caused a shortage of qualified nurses in Spain. As a result, the government authorized the hiring of senior students.Objectives:To explore the ethical dilemmas and ethical conflicts experienced by final-year nursing students who worked during the first outbreak of the COVID-19 pandemic in Spain.Research design:A qualitative exploratory study was conducted using purposive sampling. Semi-structured interviews were carried out using a question guide. Interviews took place via a private video chat room platform. A thematic, inductive (...)
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  31.  29
    Limitation of therapeutic effort experienced by intensive care nurses.Juan Francisco Velarde-García, Raquel Luengo-González, Raquel González-Hervías, César Cardenete-Reyes, Beatriz Álvarez-Embarba & Domingo Palacios-Ceña - forthcoming - Nursing Ethics:096973301667947.
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  32.  15
    Communication Skills and Professional Practice: Does It Increase Self-Efficacy in Nurses?César Leal-Costa, Sonia Tirado González, Antonio Jesús Ramos-Morcillo, María Ruzafa-Martínez, José Luis Díaz Agea & Carlos Javier van-der Hofstadt Román - 2020 - Frontiers in Psychology 11.
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  33.  4
    El concepto de tradición en el rock alternativo a partir de una lectura hermenéutica desde la propuesta filosófica de Hans-Georg Gadamer.César Augusto González Ortiz - 2022 - Escritos 30 (65):292-315.
    Este artículo parte de la pregunta de cómo el concepto de _tradición_ podría obrar en el rock alternativo a partir de una lectura hermenéutica desde la propuesta filosófica de Hans-Georg Gadamer, es decir, se pretende reconocer cómo la tradición ha estado presente y sigue estando vigentes en cada década hasta ahora en el rock alternativo. Desde esta concepción, se proponen tres maneras de hacer una interpretación de dicho concepto. En primer lugar, se toma el concepto de _tradición_, elaborado por Gadamer, (...)
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  34. Quel che resta di Heidegger, a quarant’anni dalla morte.Donatella Di Cesare, Francisco Gonzalez & Richard Polt - 2016 - Acta Philosophica 25 (2):335-346.
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  35.  30
    Using non-human primates to benefit humans: research and organ transplantation—response to César Palacios-González.Wybo Dondorp, David Shaw & Guido de Wert - 2016 - Medicine, Health Care and Philosophy 19 (2):227-228.
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  36.  16
    Entrevista com Ivan Domingues: Epistemologia das ciências humanas.Ivan Domingues, Weiny César Freitas Pinto & Allison Vicente Xavier Gonzalez - 2022 - Trans/Form/Ação 45 (3):13-32.
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  37.  8
    Numerus surdus and musical harmony. On the equal temperament and the end of the Pythagorean reign of numbers.Lianggi Espinoza, Juan Redmond, Pablo César Palacios Torres & Ismael Cortez Aguilera - 2020 - Humanities Journal of Valparaiso 16:137-167.
    The development of philosophical ideas throughout history has sometimes been assisted by the use of handcrafted instruments. Some paradigmatic cases, such as the invention of the telescope or the microscope, show that many philosophical approaches have been the result of the intervention of such instruments. The aim of this article is to show the determining role that stringed musical instruments with frets had in the crisis and generation of philosophical paradigms. In fact, just as the observations of the moon with (...)
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  38.  11
    Numerus surdus and musical harmony. On the equal temperament and the end of the Pythagorean reign of numbers.Lianggi Espinoza, Juan Redmond, Pablo César Palacios Torres & Ismael Cortez Aguilera - 2020 - Revista de Humanidades de Valparaíso 16:137-167.
    The development of philosophical ideas throughout history has sometimes been assisted by the use of handcrafted instruments. Some paradigmatic cases, such as the invention of the telescope or the microscope, show that many philosophical approaches have been the result of the intervention of such instruments. The aim of this article is to show the determining role that stringed musical instruments with frets had in the crisis and generation of philosophical paradigms. In fact, just as the observations of the moon with (...)
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  39.  23
    Beta Oscillations Distinguish Between Two Forms of Mental Imagery While Gamma and Theta Activity Reflects Auditory Attention.Mario Villena-González, Ismael Palacios-García, Eugenio Rodríguez & Vladimir López - 2018 - Frontiers in Human Neuroscience 12.
  40.  11
    Moderating Effect of the Situation of Return or Relocation on the Well-Being and Psychosocial Trauma of Young Victims of the Armed Conflict in Colombia.Sandra Milena Quintero-González, Camilo Alberto Madariaga-Orozco, Anthony Constant Millán-de Lange, Diany Marcela Castellar-Jiménez & Jorge Enrique Palacio-Sañudo - 2020 - Frontiers in Psychology 11.
    Colombia is the second country with the highest number of internally displaced persons. In the last 10 years, more than 400,000 young people carry, in their life experiences, the title of victims. The psychological and social circumstances that determine the lives of displaced young people in the world are not unknown. Fear, the poor resources for social adaptation available to them, and the possible reproduction of the cycle of violence, represent psychosocial risk factors in the young and displaced population. In (...)
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  41.  17
    Being the Victim of Intimate Partner Violence in Virtual Reality: First- Versus Third-Person Perspective.Cristina Gonzalez-Liencres, Luis E. Zapata, Guillermo Iruretagoyena, Sofia Seinfeld, Lorena Perez-Mendez, Jorge Arroyo-Palacios, David Borland, Mel Slater & Maria V. Sanchez-Vives - 2020 - Frontiers in Psychology 11.
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  42.  22
    Reducción de operaciones en la solución de sistemas de ecuaciones lineales de gran escala aplicando Simulated Annealing.Jorge Mario Arias Palacio, Julián David González Hoyos & Ramón Alfonso Gallego Rendón - forthcoming - Scientia.
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  43.  8
    Overall Quality of Sporting Events and Emotions as Predictors of Future Intentions of Duathlon Participants.Ana Mᵃ Magaz-González, César Sahelices-Pinto, Cristina Mendaña-Cuervo & Marta García-Tascón - 2020 - Frontiers in Psychology 11.
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  44. La expresión cultural= The cultural expression.César Antonio Molina, Francisco Marcos Marín, Juan González Alvaro & David Crystal - 2006 - Contrastes: Revista Cultural 44:133-135.
     
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  45. La lógica debe bastarse a sí misma.César González Ochoa - 2004 - la Lámpara de Diógenes 5 (9):71-77.
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  46.  20
    Allostatic Load Is Linked to Cortical Thickness Changes Depending on Body-Weight Status.Jonatan Ottino-González, María A. Jurado, Isabel García-García, Bàrbara Segura, Idoia Marqués-Iturria, María J. Sender-Palacios, Encarnació Tor, Xavier Prats-Soteras, Xavier Caldú, Carme Junqué & Maite Garolera - 2017 - Frontiers in Human Neuroscience 11.
  47.  11
    El eco-etnodesarrollo el chocó biogeográfico. Estudio a partir del extractivismo y las luchas Sociales por el territorio.Yennesit Palacios Valencia, Ángela Cecilia González & Diego Monsalve Builes - 2018 - Ratio Juris 13 (26):81-114.
    El objetivo del presente artículo es demostrar, desde la visión del eco-etnodesarrollo, la crisis humanitaria que padece el departamento del Chocó, teniendo en cuenta la grave afectación de los diversos grupos étnicos en sus territorios por causa del desplazamiento forzado por el conflicto armado, el riesgo en la extinción de poblaciones indígenas y tribales, las prácticas de recursos extractivos, que han puesto a los territorios en situaciones de disputa, y el narcotráfico, que evidencian la degradación que padece el departamento, ligado (...)
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  48.  15
    Increase in Beta Power Reflects Attentional Top-Down Modulation After Psychosocial Stress Induction.Ismael Palacios-García, Jaime Silva, Mario Villena-González, Germán Campos-Arteaga, Claudio Artigas-Vergara, Nicolas Luarte, Eugenio Rodríguez & Conrado A. Bosman - 2021 - Frontiers in Human Neuroscience 15.
    Selective attention depends on goal-directed and stimulus-driven modulatory factors, each relayed by different brain rhythms. Under certain circumstances, stress-related states can change the balance between goal-directed and stimulus-driven factors. However, the neuronal mechanisms underlying these changes remain unclear. In this study, we explored how psychosocial stress can modulate brain rhythms during an attentional task and a task-free period. We recorded the EEG and ECG activity of 42 healthy participants subjected to either the Trier Social Stress Test, a controlled procedure to (...)
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  49.  7
    Profesores en pandemia: identidad profesional en medios de comunicación escrita.Cindy Palacios, Javiera Mardones, Josefa Páez, Paula Cortez, David Cuadra-Martínez, Pablo J. Castro-Carrasco, Cristián Oyanadel & Ingrid González Palta - 2022 - Logos Revista de Lingüística Filosofía y Literatura 32 (2):429-446.
    Este estudio buscó describir e interpretar las teorías subjetivas sobre la identidad profesional docente que se construyen y difunden noticiosamente durante la educación de emergencia por la pandemia de COVID 19. Se utilizó un estudio de análisis documental, metodología cualitativa y un diseño de estudio de casos. El muestreo intencionado y por conveniencia corresponde a 40 noticias de prensa escrita en español, sobre el profesor(a) en pandemia y publicadas en diferentes medios que fueron recolectadas a través de Google Noticias desde (...)
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  50.  29
    Exploring the Link Between Human Rights, the Capability Approach and Corporate Responsibility.César González-Cantón, Sonia Boulos & Pablo Sánchez-Garrido - 2019 - Journal of Business Ethics 160 (4):865-879.
    The capability approach is gaining momentum as a theory of corporate responsibility and business ethics at a time when the UN Guiding Principles have become a most important framework. A novel approach is now emerging that seeks to understand and specify human rights obligations of businesses within the framework provided by the capability approach. This article partially examines the triad corporate responsibility–human rights–capability approach by exploring the relationship between human rights and capabilities. Thus, it offers conceptual and practical implications for (...)
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