Essays examine the role of science in modern society and discusses the influence of economic, ethical, and political factors on science.

This chapter contains sections titled: The Gods Problem The Evolution of Free Will Is Our Starting Point So Gods Evolved Gods Are Hidden Inside Us The Godless Must Walk the Earth Gods Must Be Made Manifest Religion Mediates Between Free Will and Gods Living in Harmony With Our Actual Gods.

The career of the father of Claudius Etruscus is of special importance in the history of the Imperial administration in the first century A.D. In the course of a long life he rose from slave status under Tiberius to be head of the Imperial financial administration and to equestrian status under Vespasian. He was one of the most important, wealthy, and influential of the Imperial freedmen in the first century when their influence was at its peak; he is one (...) of the best documented of their number outside the pages of Tacitus; yet we do not know his personal name—he has to remain simply ‘the father of Claudius Etruscus’ —and even his nomen gentilicium and the date of his appointment to be the secretary a rationibus are subject to disput. (shrink)

In his paper entitled “Ethics and the Funding of Research and Development at Universities”1 Spier examines some of the potential problems of the relationship between 1) corporate sponsors of research and 2) the universities (and faculty) that receive that funding. Citing “He who pays the piper, calls the tune,” Spier suggests that a better way of funding research would be to “set up a dedicated publicly sponsored research establishment” with the stated goal of achieving particular technical or engineering objectives. (Spier (...) cited the successful Animal Virus Research of the UK as an example). Spier states that researchers at these establishments are “not subjected to the triple requirement to teach, research and administer as are university members, so they do not have to face the same ethical challenges of the academics.” This paper will examine the stated dangers of public/corporate research partnerships and whether the proposed alternative shares equally troubling ethical issues. (shrink)

BackgroundResponsive neurostimulation has been utilized as a treatment for intractable epilepsy. The RNS System delivers stimulation in response to detected abnormal activity, via leads covering the seizure foci, in response to detections of predefined epileptiform activity with the goal of decreasing seizure frequency and severity. While thalamic leads are often implanted in combination with cortical strip leads, implantation and stimulation with bilateral thalamic leads alone is less common, and the ability to detect electrographic seizures using RNS System thalamic leads is (...) uncertain.ObjectiveThe present study retrospectively evaluated fourteen patients with RNS System depth leads implanted in the thalamus, with or without concomitant implantation of cortical strip leads, to determine the ability to detect electrographic seizures in the thalamus. Detailed patient presentations and lead trajectories were reviewed alongside electroencephalographic analyses.ResultsAnterior nucleus thalamic leads, whether bilateral or unilateral and combined with a cortical strip lead, successfully detected and terminated epileptiform activity, as demonstrated by Cases 2 and 3. Similarly, bilateral centromedian thalamic leads or a combination of one centromedian thalamic alongside a cortical strip lead also demonstrated the ability to detect electrographic seizures as seen in Cases 6 and 9. Bilateral pulvinar leads likewise produced reliable seizure detection in Patient 14. Detections of electrographic seizures in thalamic nuclei did not appear to be affected by whether the patient was pediatric or adult at the time of RNS System implantation. Sole thalamic leads paralleled the combination of thalamic and cortical strip leads in terms of preventing the propagation of electrographic seizures.ConclusionThalamic nuclei present a promising target for detection and stimulation via the RNS System for seizures with multifocal or generalized onsets. These areas provide a modifiable, reversible therapeutic option for patients who are not candidates for surgical resection or ablation. (shrink)

Judgments of direct comparisons, probabilities, proportions, and ranks can all be considered referent-specific judgments, for which a good estimate requires a target to be compared against...

It is correctly asserted that the intensity of the current debate over the use of animals in biomedical research is unprecedented. The extent of expressed animosity and distrust has stunned many researchers. In response, researchers have tended to take a strategic defensive posture, which involves the assertion of several abstract positions that serve to obstruct resolution of the debate. Those abstractions include the notions that the animal protection movement is trivial and purely anti-intellectual in scope, that all science is good (...) (and some especially so), and the belief that an ethical consensus can never really be reached between the parties. (shrink)

In cognitive science, there is a tacit norm that phenomena such as cultural variation or synaesthesia are worthy examples of cognitive diversity that contribute to a better understanding of cognition, but that other forms of cognitive diversity (e.g., autism, attention deficit hyperactivity disorder/ADHD, and dyslexia) are primarily interesting only as examples of deficit, dysfunction, or impairment. This status quo is dehumanizing and holds back much-needed research. In contrast, the neurodiversity paradigm argues that such experiences are not necessarily deficits but rather (...) are natural reflections of biodiversity. Here, we propose that neurodiversity is an important topic for future research in cognitive science. We discuss why cognitive science has thus far failed to engage with neurodiversity, why this gap presents both ethical and scientific challenges for the field, and, crucially, why cognitive science will produce better theories of human cognition if the field engages with neurodiversity in the same way that it values other forms of cognitive diversity. Doing so will not only empower marginalized researchers but will also present an opportunity for cognitive science to benefit from the unique contributions of neurodivergent researchers and communities. (shrink)

Three studies were conducted to explore the psychological determinants of COVID-deterrent behaviors. In Study 1, using data collected and analyzed both before and after the release of COVID-19 vaccines, mask-wearing, other preventative behaviors like social distancing, and vaccination intentions were positively related to assessments of the Coronavirus Behavioral Health Mindset ; belief in the credibility of science; progressive political orientation; less use of repressive and more use of sensitization coping; and the attribution of COVID-19 safety to effort rather than ability, (...) powerful forces, fate, or luck. In Study 2, favorable COVID-19 vaccination intentions were related to greater willingness to work, lower emotional distress, and greater customer experience mindset. Study 3 examined the personality and motives of individuals who volunteered to help deliver COVID-19 inoculations to the local community. The vaccine-giving volunteers, especially those with prosocial motives, had high CVBHM scores, belief in the credibility of science, low use of repressive coping, greater attribution of COVID-19 protection to effort, low likelihood of voting conservative, were older, and had more education than others. The majority of public health volunteers expressed prosocial motives to help people or join a cause, but many expressed the personal motives of getting the COVID-19 vaccination for themselves, conveying a public image of compassion, or structuring time. Based on the three research studies, a COVID-19 Mindset Hierarchy model is proposed to integrate the results. (shrink)

This article is the lead piece in a special report that presents the results of a bioethical investigation into chimeric research, which involves the insertion of human cells into nonhuman animals and nonhuman animal embryos, including into their brains. Rapid scientific developments in this field may advance knowledge and could lead to new therapies for humans. They also reveal the conceptual, ethical, and procedural limitations of existing ethics guidance for human‐nonhuman chimeric research. Led by bioethics researchers working closely with an (...) interdisciplinary work group, the investigation focused on generating conceptual clarity and identifying improvements to governance approaches, with the goal of helping scholars, funders, scientists, institutional leaders, and oversight bodies (embryonic stem cell research oversight [ESCRO] committees and institutional animal care and use committees [IACUCs]) deliver principled and trustworthy oversight of this area of science. The article, which focuses on human‐nonhuman animal chimeric research that is stem cell based, identifies key ethical issues in and offers ten recommendations regarding the ethics and oversight of this research. Turning from bioethics’ previous focus on human‐centered questions about the ethics of “humanization” and this research's potential impact on concepts like human dignity, this article emphasizes the importance of nonhuman animal welfare concerns in chimeric research and argues for less‐siloed governance and oversight and more‐comprehensive public communication. (shrink)

There have been many attempts of late to formulate a satisfactory theory of knowledge with which to replace the traditional justified true belief analysis. Almost all agree that it must be the case that in order for S to know that p; i.) p be true, and ii.) S believe that p. Although many argue that there must be a condition stating that S has adequate evidence for p, requirements other than i.) and ii.) are controversial. The most popular approach (...) taken, however, is the addition of a requirement to the effect that for S to know that p there must be no other evidence against p strong enough to undermine S's belief that p, should this evidence come to S's attention. I shall call such a requirement a “defeasibility condition” and any theory containing such a requirement a defeasibility theory.Defeasibility theories are quite effective in handling a certain kind of difficulty to which theories of knowledge are subject, namely problems dealing with what Harman has termed the social aspect of knowledge. (shrink)

Peter Abelard (1079–1142 ce) was the most wide‐ranging philosopher of the twelfth century. He quickly established himself as a leading teacher of logic in and near Paris shortly after 1100. After his affair with Heloise, and his subsequent castration, Abelard became a monk, but he returned to teaching in the Paris schools until 1140, when his work was condemned by a Church Council at Sens. His logical writings were based around discussion of the “Old Logic”: Porphyry's Isagoge, aristotle'S Categories and (...) On Interpretation and boethius'S textbook on topical inference. They comprise a freestanding Dialectica (“Logic”; probably c.1116), a set of commentaries (known as the Logica [Ingredientibus], c. 1119) and a later (c. 1125) commentary on the Isagoge (Logica Nostrorum Petititoni Sociorum or Glossulae). In a work Abelard called his Theologia, issued in three main versions (between 1120 and c.1134), he attempted a logical analysis of trinitarian relations and explored the philosophical problems surrounding God's claims to omnipotence and omniscience. The Collationes (“Debates,” also known as “Dialogue between a Christian, a Philosopher and a Jew”; probably c.1130) present a rational investigation into the nature of the highest good, in which the Christian and the Philosopher (who seems to be modeled on a philosopher of pagan antiquity) are remarkably in agreement. The unfinished Scito teipsum (“Know thyself,” also known as the “Ethics”; c.1138) analyses moral action. (shrink)

Which sounds composed the first spoken languages? Archetypal sounds are not phylogenetically or archeologically recoverable, but comparative linguistics and primatology provide an alternative approach. Labial articulations are the most common speech sound, being virtually universal across the world's languages. Of all labials, the plosive ‘p’ sound, as in ‘Pablo Picasso’, transcribed /p/, is the most predominant voiceless sound globally and one of the first sounds to emerge in human infant canonical babbling. Global omnipresence and ontogenetic precocity imply that /p/‐like sounds (...) could predate the first major linguistic diversification event(s) in humans. Indeed, great ape vocal data support this view, namely, the only cultural sound shared across all great ape genera is articulatorily homologous to a rolling or trilled /p/, the ‘raspberry’. /p/‐like labial sounds represent an ‘articulatory attractor’ among living hominids and are likely among the oldest phonological features to have ever emerged in linguistic systems. (shrink)

Introduction While quizzing during informed consent for research to ensure understanding has become commonplace, it is unclear whether the quizzing itself is problematic for potential participants. In this study, we address this issue in a multinational HIV prevention research trial enrolling injection drug users in China and Thailand. Methods Enrolment procedures included an informed consent comprehension quiz. An informed consent survey followed. Results 525 participants completed the informed consent survey (Heng County, China=255, Xinjiang, China=229, Chiang Mai, Thailand=41). Mean age was (...) 33 and mean educational level was 8 yrs. While quizzing was felt to be a good way to determine if a person understands the nature of clinical trial participation (97%) and participants did not generally find the quiz to be problematic, minorities of respondents felt pressured (6%); anxious (5%); bored (5%); minded (5%); and did not find the questions easy (13%). In multivariate analysis, lower educational level was associated with not minding the quizzing (6–10 yrs vs 0–5 yrs: OR=0.27, p=0.03; more than 11 yrs vs 0–5 yrs: OR=0.18, p=0.03). There were also site differences (Heng County vs Xinjiang) in feeling anxious (OR=0.07; p=<0.01), not minding (OR=0.26; p=0.03), being bored (OR=0.25; p=0.01) and not finding the questions easy (OR=0.10; p=<0.01). Conclusions Quizzing during the informed consent process can be problematic for a minority of participants. These problems may be associated with the setting in which research takes place and educational level. Further research is needed to develop, test and implement alternative methods of ensuring comprehension of informed consent. Trial Registration clinicaltrials.gov number NCT00270257. (shrink)

Some recent work in the philosophy of quantum mechanics has suggested that quantum systems can be thought of as non-separable and therefore non-individual, in some sense, in Bell and E.P.R. type situations. This suggestion is set in the context of previous work regarding the individuality of quantal particles and it is argued that such entities can be considered as individuals if their non-classical statistical correlations are understood in terms of non-supervenient relations holding between them. We conclude that such relations are (...) strongly non-supervenient in Cleland's sense and note a possible connection between this idea and the realist quantum logic programme. (shrink)

Let T be superstable. We say a type p is weakly minimal if R(p, L, ∞) = 1. Let $M \models T$ be uncountable and saturated, H = p(M). We say $D \subset H$ is locally modular if for all $X, Y \subset D$ with $X = \operatorname{acl}(X) \cap D, Y = \operatorname{acl}(Y) \cap D$ and $X \cap Y \neq \varnothing$ , dim(X ∪ Y) + dim(X ∩ Y) = dim(X) + dim(Y). Theorem 1. Let p ∈ S(A) be weakly (...) minimal and D the realizations of $\operatorname{stp}(a/A)$ for some a realizing p. Then D is locally modular or p has Morley rank 1. Theorem 2. Let H, G be definable over some finite A, weakly minimal, locally modular and nonorthogonal. Then for all $a \in H\backslash\operatorname{acl}(A), b \in G\operatorname{acl}(A)$ there are a' ∈ H, b' ∈ G such that $a' \in \operatorname{acl}(abb' A)\backslash\operatorname{acl}(aA)$ . Similarly when H and G are the realizations of complete types or strong types over A. (shrink)

This article is part of a For-Discussion-Section of Methods of Information in Medicine about the paper "Biomedical Informatics: We Are What We Publish", written by Peter L. Elkin, Steven H. Brown, and Graham Wright. It is introduced by an editorial. This article contains the combined commentaries invited to independently comment on the Elkin et al. paper. In subsequent issues the discussion can continue through letters to the editor.

CONTENTS Rudolf Bernet: Husserl's Transcendental Idealism Revisited Ian Angus: In Praise of Fire: Responsibility, Manifestation, Polemos, Circumspection Dieter Lohmar: Husserl's Hesitant Revisionism in the Field of Logic Torsten Pietrek: A Reconstruction of Phenomenological Method for Metaethics Renaud Barabas: Sensing and Creating: Phenomenology and the Unity of Aesthetics Christian Lotz: Recollection, Mourning and the Absolute Past. Husserl, Freud and Derrida Karlheinz Ruhstorfer: Adieu: Derrida's God and the Beginning of Thinking Rosemary R. P. Lerner: Husserl vs. Neo-Kantianism Revisited: On Skepticism, Foundationalism, and (...) Intuition Sebastian Luft: A Hermeneutic Phenomenology of Subjective and Objective Spirit: Husserl, Natorp and Cassirer Marcus Brainard: Husserl on Nature and Spirit Edmund Husserl: On Smoking (German/English) Johannes Daubert: Notes from Husserl's Mathematical-Philosophical Exercises (1905), ed. and intro. Mark van Atten and Karl Schuhmann (German/English) Dorion Cairns: On Eugen Fink's "The Problem of Husserl's Phenomenology". (shrink)

This paper articulates a formal theory of belief incorporating three key theses: (1) belief is a dyadic relation between an agent and a property; (2) this property is not the belief's truth condition (i.e., the intuitively self-ascribed property which the agent must exemplify for the belief to be true) but is instead a certain abstract property (a "thought-content") which contains a way of thinking of that truth condition; (3) for an agent a to have a belief "about" such-and-such items it (...) is necessary that a possesses a language of thought, $M_{a}$ , and that a (is disposed as one who) inwardly affirms a sentence of $M_{a}$ in which there are terms that denote those objects. Employing an extended version of E. Zalta's system ILAO, the proffered theory locates thought-contents within a typed hierarchy of "senses" and their "modes of presentation", the provisional definitions of which (suppressing complications added later to accommodate the contents of beliefs about beliefs) are as follows. A mode of presentation of e is a ternary relation of the sort [λxyz z is a name in $M_{y}$ that denotes x, and $D_{e}yz$ ] in which $D_{e}$ is an e-determiner - a relation between agents and their mental expressions imposing a syntactico-semantic condition sufficient for such an expression to denote e therein. A sense of an entity e is an abstract property that "contains" a mode of presentation $R_{e}$ of e by dint of encoding its property-reduct [λx(∃y)(∃z) $R_{e}xyz$ ]. In particular, a thought-content is a sense T of an ordinary first-order property P containing a mode of presentation whose P-determiner $D_{P}$ is such that, for any y and z, $D_{P}yz$ entails that z is a λ-abstract [λv S] of $M_{y}$ in which S is a sentence whose non-logical parts stand in appropriate semantic relations to the constituents of T's (some of which may themselves be senses). Where $I_{a}$ is agent a's dedicated self-demonstrative and |T| is the mode of presentation contained in a thought-content T, the belief relation itself is then characterized as obtaining between a and T iff a( is disposed as one who) inwardly affirms the substitution instance $S(I_{a}/v)$ of a sentence S in $M_{a}$ such that |T|(P, a, [λv S]). The aforementioned "constituents" and "appropriate semantic relations" are formally characterized so as to permit a system of canonical descriptions for thought-contents of arbitrary complexity. These canonical descriptions are then employed to chart the nature and interrelations of belief de re, de dicto and de se and to identify the source of opacity in belief ascription. (shrink)

Moral Problems in Higher Education brings together key essays that explore ethical issues in academia. The editor and contributors-all noted philosophers and educators-consider such topics as academic freedom and tenure, free speech on campus, sexual harassment, preferential student admissions, affirmative action in faculty appointments, and the ideal of a politically neutral university. Chapters address possible restrictions on research because of moral concerns, the structure of peer review, telling the truth to colleagues and students, and concerns raised by intercollegiate athletics. Cahn (...) selects two key readings in each area to offer a readable introductory guide to these critical subjects for students studying academic ethics and higher education policy. In addition to the selections and a general introduction, Cahn provides study questions for use in the classroom. Contributors include Scott F. Aikin, Derek Bok, William G. Bowen, Myles Brand, Richard T. DeGeorge, Paul D. Eisenberg, Leslie Pickering Francis, Martin P. Golding, Philip Kitcher, Charles R. Lawrence III, David Lewis, Paul J. Olscamp, Nancy Tuana, David Shatz, George Sher, Robert L. Simon, Robert B. Talisse, Stephan Thernstrom, Abigail Thernstrom, Laurence Thomas, Robert Paul Wolff, and the editor. (shrink)

Theorem A. Suppose that T is superstable and p is a nontrivial type of U-rank 1. Then R(p, L, ∞) = 1. Theorem B. Suppose that T is totally transcendental and p is a nontrivial type of U-rank 1. Then p has Morley rank 1.

Suppose T is superstable. Let ≤ denote the fundamental order on complete types, [ p] the class of the bound of p, and U(--) Lascar's foundation rank (see [LP]). We prove THEOREM 1. If $q and there is no r such that $q , then U(q) + 1 = U(p). THEOREM 2. Suppose $U(p) and $\xi_1 is a maximal descending chain in the fundamental order with ξ κ = [ p]. Then k = U(p). That the finiteness of U(p) in (...) Theorem 2 is necessary follows from THEOREM 3. There is an ω-stable theory with a type p ∈ S 1 (φ) such that (1) U(p) = ω + 1, and (2) there is a maximal descending chain of proper extensions of [ p] which has order type ω. (shrink)

In this paper I examine two arguments, one by R. A. Oakes and the other by P. A. Byrne, that Berkeley's immaterialism is the only metaphysic consistent with classical theism. I show that not only do Oakes and Byrne fail to demonstrate the incompatibility of physical realism with classical theism, but also that their line of argument reveals a grave inconsistency between the latter and immaterialism. For as they expound Berkeley's metaphysic, it seems incapable of explicating the metaphysical dependency of (...) finite spirit (mind) on God. (shrink)