Risk analysis and regulatory systems are usually evaluated according to utilitarian frameworks, as they are viewed to operate “objectively” by considering the health, environmental, and economic impacts of technological applications. Yet, the estimation of impacts during risk analysis and the decisions in regulatory review are affected by value choices of actors and stakeholders; attention to principles such as autonomy, justice, and integrity; and power relationships. In this article, case studies of biotechnology are used to illustrate how non-utilitarian principles are prominent (...) in risk analysis and regulatory review and to argue that these relationships should be carefully considered as we consider nanotechnology oversight systems for its products. We argue that there are not distinct separations between “science-based” review systems, in which evaluations of the consequences of technological products are primarily considered, and principles of integrity, justice, non-maleficence, and autonomy. It should further be expected that, given research into fair treatment during decision-making processes, attention to ethics will affect how citizens assess emerging technologies. Finally, a more holistic approach for evaluating oversight systems for the products of nanotechnology is suggested, one which does not draw a sharp distinction between risk analysis, regulation, and respect for non-utilitarian values. (shrink)

The U.S. oversight system for genetically engineered organisms was evaluated to develop hypotheses and derive lessons for oversight of other emerging technologies, such as nanotechnology. Evaluation was based upon quantitative expert elicitation, semi-standardized interviews, and historical literature analysis. Through an interdisciplinary policy analysis approach, blending legal, ethical, risk analysis, and policy sciences viewpoints, criteria were used to identify strengths and weaknesses of GEOs oversight and explore correlations among its attributes and outcomes. From the three sources of data, hypotheses and broader (...) conclusions for oversight were developed. Our analysis suggests several lessons for oversight of emerging technologies: the importance of reducing complexity and uncertainty in oversight for minimizing financial burdens on small product developers; consolidating multi-agency jurisdictions to avoid gaps and redundancies in safety reviews; consumer benefits for advancing acceptance of GEO products; rigorous and independent pre- and post-market assessment for environmental safety; early public input and transparency for ensuring public confidence; and the positive role of public input in system development, informed consent, capacity, compliance, incentives, and data requirements and stringency in promoting health and environmental safety outcomes, as well as the equitable distribution of health impacts. Our integrated approach is instructive for more comprehensive analyses of oversight systems, developing hypotheses for how features of oversight systems affect outcomes, and formulating policy options for oversight of future technological products, especially nanotechnology products. (shrink)

U.S. approaches to oversight of research and technological products have developed over time in an effort to ensure safety to humans, animals, and the environment and to control use in a social context. In modern times, regulatory and oversight tools have evolved to include diverse approaches such as performance standards, tradable allowances, consultations between government and industry, and pre-market safety and efficacy reviews. The decision whether to impose an oversight system, the oversight elements, the level of oversight, the choice of (...) approach, and its execution can profoundly affect technological development, individual and collective interests, and public confidence in technological products. Oversight is conducted by a range of institutions with various capabilities, cultures, and motives. Avenues for disputing oversight decisions are also important, and some argue that the U.S. operates in an adversarial regulatory culture in which Congress, the media, and stakeholders regularly contest the decisions of federal agencies. (shrink)

There is a “revolving door” between federal agencies and the industries regulated by them. Often, at the end of their industry tenure, key industry personnel seek employment in government regulatory entities and vice versa. The flow of workers between the two sectors could bring about good. Industry veterans might have specialized knowledge that could be useful to regulatory bodies and former government employees could help businesses become and remain compliant with regulations. But the “revolving door” also poses at least three (...) ethical and policy challenges that have to do with public trust and fair representation. First, the presence of former key industry personnel on review boards could adversely impact the public’s confidence in regulatory decisions about new technology products, including agrifood biotechnologies. Second, the ‘‘revolving door’’ may result in policy decisions about technologies that are biased in favor of industry interests. And third, the ‘‘revolving door’’ virtually guarantees industry a voice in the policy-making process, even though other stakeholders have no assurance that their concerns will be addressed by regulatory agencies. We believe these three problems indicate a failure of regulatory review for new technologies. The review process lacks credibility because, at the very least, it is procedurally biased in favor of industry interests. We argue that prohibiting the flow of personnel between regulatory agencies and industry would not be a satisfactory solution to the three problems of public trust and just representation. To address them, regulatory entities must reject the traditional notion of objectivity. Instead they should adopt the conception of objectivity developed by Sandra Harding and re-configure their regulatory review on the basis of it. That will ensure that a heterogeneous group of stakeholders is at the decision-making table. The fair representation of interests of different constituencies in the review process could do much to inspire warranted public confidence in regulatory protocols and decisions. (shrink)

Allhoff, Fritz, Patrick Lin, and Daniel Moore. 2010. What is nanotechnology and why does it matter? From science to ethics Content Type Journal Article Pages 209-211 DOI 10.1007/s11673-011-9289-z Authors Jennifer Kuzma, University of Minnesota, Humphrey School of Public Affairs, 301 19th Ave So, Minneapolis, MN 55455, USA Journal Journal of Bioethical Inquiry Online ISSN 1872-4353 Print ISSN 1176-7529 Journal Volume Volume 8 Journal Issue Volume 8, Number 2.

The article looks at the state of women’s and gender history at Polish universities, taking the international context—especially the case of the United States, France, Great Britain, and Germany—as a point of departure for analyzing the specificities of the Polish situation. It is argued that the weak position of women’s history and virtual nonexistence of gender history are caused by the following reasons: the dominance of political history, resistance to theory, a general lack of interdisciplinary approaches, reluctance to feminism, structural (...) inflexibility and hierarchy that characterize Polish universities. At the same time, the integration of gender history approaches into research is claimed to be a chance for the development and more widespread acceptance of women’s history, as well as for greater inclusion of theory into Polish historical research. (shrink)

The article looks at the state of women’s and gender history at Polish universities, taking the international context—especially the case of the United States, France, Great Britain, and Germany—as a point of departure for analyzing the specificities of the Polish situation. It is argued that the weak position of women’s history and virtual nonexistence of gender history are caused by the following reasons: the dominance of political history, resistance to theory, a general lack of interdisciplinary approaches, reluctance to feminism, structural (...) inflexibility and hierarchy that characterize Polish universities. At the same time, the integration of gender history approaches into research is claimed to be a chance for the development and more widespread acceptance of women’s history, as well as for greater inclusion of theory into Polish historical research. (shrink)

Maurice Blanchot Though Maurice Blanchot’s status as a major figure in 20th century French thought is indisputable, it is debatable how best to classify his thought and writings. To trace the itinerary of Blanchot’s development as a thinker and writer is to traverse the span of 20th century French intellectual history, as Blanchot lived … Continue reading Blanchot, Maurice →.

O artigo que apresentamos tem a intenção de refletir sobre a vocação e missão dos leigos descritas no Documento de Medellín, dedica-se a um resgate das memórias que podemos colher, depois de 50 anos, mas, também, em atenção às novas perspectivas que o próprio documento nos traz, hoje. Medellín foi um marco importante para a história da Igreja da América Latina e voltar a esta conferência pode nos oferecer novas pistas e novos entendimentos para situações que vivemos hoje, tanto na (...) Igreja quanto na sociedade. Assim como o Concílio Vaticano II, Medellín foi importante para uma nova posição dos leigos na Igreja e para um novo entendimento de sua ação na sociedade, com autonomia e responsabilidades próprias. Neste artigo, daremos atenção ao Concílio Vaticano II e a sua recepção criativa em Medellín. Exploraremos aspectos do capítulo que trata exclusivamente dos leigos e, na sequência, discorreremos sobre algumas questões que o tema provoca e que, depois de 50 anos, mostram-se atuais e oferecem novos caminhos. (shrink)

In Laudato si’, Pope Francis says that the way to begin solving environmental problems is by “learning to see and appreciate beauty”. Environmental ethicists have long known that beauty motivates people to protect nature. What form that takes depends upon how one defines beauty. In A Sand County Almanac, Aldo Leopold shares not only his famous land ethic, but also a land aesthetic. This paper will show that Laudato si’ and A Sand County Almanac present similar aesthetics emphasizing receptivity to (...) objective natural beauty. First, I will consider Pope Francis’s uses of beauty. I then look to how environmental ethicists have evaluated beauty to determine what makes an environmental aesthetic robust rather than superficial. Finally, I examine how A Sand County Almanac both demonstrates receptivity and forms the reader to be receptive. I contend that reading A Sand County Almanac represents one way to practice Pope Francis’s instructions. (shrink)

Novel targeted genetic modification techniques for plants have the potential to increase the speed and ease of genetic modification and fall outside existing regulatory authority. We conducted 31 interviews with expert-stakeholders to explore the differing visions they have for the future of plant TagMo environmental regulation. To guide our analysis we review the tenets of anticipatory governance in light of future studies literature on emerging technology, focusing on how to contribute to reflexivity by making explicit the assumptions within envisioned futures. (...) Our findings reveal that the environmental regulation futures articulated by expert-stakeholders could be classified into three categories—optimistic, pragmatic, and critical—based on their differing underlying assumptions concerning what constitutes environmental risk and the adequacy of existing U.S. genetically modified plant regulations. By gathering these diverse perspectives on the future and studying how they differ, we hope to further the anticipatory governance-informed engagement with regulation and foster a more productive discussion of plant TagMo regulation. (shrink)

Growing public concern and uncertainties surrounding emerging technologies suggest the need for socially-responsible behavior of companies in the development and implementation of oversight systems for them. In this paper, we argue that corporate social responsibility (CSR) is an important aspect of nanotechnology oversight given the role of trust in shaping public attitudes about nanotechnology and the lack of data about the health and environmental risks of nanoproducts. We argue that CSR is strengthened by the adoption of stakeholder-driven models and attention (...) to moral principles in policies and programs. In this context, we examine drivers of CSR, contextual and leadership factors that influence CSR, and strategies for CSR. To illustrate these concepts, we discuss existing cases of CSR-like behavior in nanotechnology companies, and then provide examples of how companies producing nanomedicines can exhibit morally-driven CSR behavior. (shrink)

The Eroticization of Distance engages with the theme of eroticism in Blanchot’s writings, and uncovers the nature of Nietzsche’s influence upon Blanchot’s writings of the 1940s and early 1950s.

The emergence of nanotechnology, and specifically nanobiotechnology, raises major oversight challenges. In the United States, government, industry, and researchers are debating what oversight approaches are most appropriate. Among the federal agencies already embroiled in discussion of oversight approaches are the Food and Drug Administration , Environmental Protection Agency , Department of Agriculture , Occupational Safety and Health Administration , and National Institutes of Health . All can learn from assessment of the successes and failures of past oversight efforts aimed at (...) emerging technologies. This article reports on work funded by the National Science Foundation aimed at learning the lessons of past oversight efforts. The article offers insights that emerge from comparing five oversight case studies that examine oversight of genetically engineered organisms in the food supply, pharmaceuticals, medical devices, chemicals in the workplace, and gene therapy. Using quantitative and qualitative analysis, the authors present a new way of evaluating oversight. (shrink)

The diversity of nanotechnologies and of the governance challenges that their applications raise calls for exploration and learning across different cases. We present an Upstream Oversight Assessment (UOA) of expected benefits and potential harms of nanoparticles made of a synthetic polymer (PLGA) to improve vaccines for farmed salmon. Suggested by Jennifer Kuzma and colleagues, an UOA may help identify and prioritise research needs, and it may support evaluations of the adequacy of relevant existing regulatory frameworks. In this work, the UOA (...) approach is modified and supported with elements from the uncertainty analysis framework developed by Warren Walker and colleagues. Empirically, we draw on relevant available published literature and insights generated in an ongoing nanoparticle salmon vaccine project, in which one of the authors participates. Nanotechnologies have not previously been encountered in the regulatory context of fish vaccines, which in part raises unique challenges due to prospective large scale vaccine use in semi-open aquatic systems. Strengthened through cooperation between ELSA and technology researchers we found the UOA useful for an early mapping of benefits and concerns, and for identifying areas in need of further research prior to a nanoparticle based salmon vaccine is developed and taken into use. We consider our approach to represent one among several complementing initiatives that seek to contribute to early stage evaluations of possible negative side effects, broadly conceived, in order to facilitate a more robust nanotechnology development. (shrink)

Filozoficzne rozważania na temat cywilizacji w ostatecznym rozrachunku stoją pod znakiem zapytania o ich prawomocność. Zdawałoby się, iż studia cywilizacyjne winnioemy zostawiæ antropologom, historykom, politologom i innym przedstawicielom nauk szczegółowych. Filozofie cywilizacji natomiast powinny zostać odłożone do antykwariatu doktryn spekulatywnych. Odpowiedź filozofów na takie pytanie da się łatwo przewidzieć: każda teoria cywilizacji zakłada jakąś jej filozofię. Ale typów tej filozofii jest ledwie kilka, przeto zasadne jest pytanie, czy wobec postępów kulturoznawstwa istnieją jakieś powody – poza antykwarycznymi,które usprawiedliwiałyby referowanie dawnych koncepcji (...) tego czy innego rodzaju, skoro mamy nowsze, w domyśle: zbudowane przy pomocy wyników aktualnych badań, a przede wszystkim jakoś uwzględniające wydarzenia, które zaszły na przełomie XX w. A jednak kumulatywny postęp nauk szczegółowych, szczególnie społecznych nie zawsze koreluje z dopracowywaniem ich paradygmatów. Bywa wręcz odwrotnie, przez co pierwotna postać jakiejś idei filozoficznej może okazać się bogatsza i po prostu ciekawsza niż jej późniejsze formy. Czasami postać pierwotna lepiej ujawnia swój aspekt spekulatywny, zamaskowany późniejszymi, kolejnymi próbami „naukowego udowodnienia”. Zdarza się i tak, że oryginalna idea filozoficzna zostaje zarzucona z przyczyn politycznych albo przeciwnie, ulega upolitycznieniu. Przykładami są dwie doktryny, które zestawiamy w niniejszym artykule. W naszym pojęciu egzemplifikują przeciwstawne a uzupełniające się paradygmaty nauki o kulturze. To, że stworzyli je Polacy: Feliks Koneczny i Erazm Majewski jest z historycznego punktu widzenia znamienne, choć rzecz jasna nie wpływa na ich analizę. Zresztą, o ile wiemy, doktryny Konecznego i Majewskiego nie były jeszcze systematycznie porównywane. A jest to chyba porównanie interesujące samo w sobie, skoro z jednej strony Majewski był, obok Spencera i Znanieckiego, jednym z głównych źródeł inspiracji doktryny Konecznego, a z drugiej sam jest godzien uwagi, niezależnie od paradygmatu, który reprezentuje. […]. (shrink)

Five years ago, the Journal of Nietzsche Studies published a special issue on Nietzsche and the affects. In it, Aurelia Armstrong wrote generically about the passions, Michael Ure discussed Schadenfreude, Joanne Faulkner addressed disgust, and Joseph Kuzma focused on eroticism.1 In subsequent issues, authors have discussed love,2 emotion in general,3 resentment,4 compassion,5 honor and empathy,6 and affect in general.7 This special section on emotions and reactive attitudes is a chance to take stock of the progress we have made as a (...) field, draw connections among the affects and emotions addressed in the secondary literature, and introduce new ideas and tools for future research.If the articles here are any... (shrink)

This commentary provides a brief overview of the methods and results presented by Jennifer Kuzma, Pouya Najmaie, and Joel Larson in “Evaluating Oversight Systems for Emerging Technologies: A Case Study of Genetically Engineered Organisms.” It offers suggestions regarding how supplemental information might be used to gain additional insights into the authors' results and how future research could further enhance our understanding of the attributes and outcomes of regulatory oversight for genetically engineered organisms.

This paper reviews the paper by Kuzma, Najmaie, and Larson that looks at what can be learned from the experience with genetically engineered organisms for oversight of emerging technologies more generally. That paper identifies key attributes of a good oversight system: promoting innovation, ensuring safety, identifying benefits, assessing costs, and doing so all while building public confidence. In commenting on that analysis, this paper suggests that looking at “oversight” in three phases — research and development, regulatory review, and market acceptance (...) — can help to determine when certain of these attributes should take precedence over others and how to structure remedies when an error occurs. The result is an approach that is precautionary with respect to research and development, prudent and open to public input in the regulatory review stage, and purposefully persuasive once market acceptability is at stake, with remedies that are risk-containing in the first phase, risk-managing in the second, and risk-assuaging in the third. Combining the key attributes with the idea of three phases can help attune oversight to society's needs. (shrink)