What precisely does it mean to unify fields like the electric and magnetic field to only one field? Are there different kinds of unification? Is there only ‘unified’ and ‘not unified’, or could a unififcation of fields also be partially succesful? I will argue that what is normally referred to as the project of a unified field theory is actually a bundle of three research programmes that are logically independent of each other. The sub-programmes are those of a unified field (...) theory, a complete field theory, and a geometrised field theory. Here I will focus on the programme of a unified field theory in a narrow sense. In particular, I will make use of an almost unknown debate between Einstein and Pauli about which criteria a unification of fields should fulfil, in order to distinguish between different degrees of unification in field theories. (shrink)

An image of God that isn't true -- The God of creation -- The God of no use -- The God of our imagination -- The God of thunder -- The God of terror -- The God of surrender -- The God of intimacy -- The God of consolation -- The God of incarnation -- The God of rebirth -- The adventurous God.

This volume is the first systematic presentation of the work of Albert Einstein, comprising fourteen essays by leading historians and philosophers of science that introduce readers to his work. Following an introduction that places Einstein's work in the context of his life and times, the book opens with essays on the papers of Einstein's 'miracle year', 1905, covering Brownian motion, light quanta, and special relativity, as well as his contributions to early quantum theory and the opposition to his light quantum (...) hypothesis. Further essays relate Einstein's path to the general theory of relativity and the beginnings of two fields it spawned, relativistic cosmology and gravitational waves. Essays on Einstein's later years examine his unified field theory program and his critique of quantum mechanics. The closing essays explore the relation between Einstein's work and twentieth-century philosophy, as well as his political writings. (shrink)

The dynamic structure and composition of lipid membranes need to be tightly regulated to control the vast array of cellular processes from cell and organelle morphology to protein‐protein interactions and signal transduction pathways. To maintain membrane integrity, sense‐and‐response systems monitor and adjust membrane lipid composition to the ever‐changing cellular environment, but only a relatively small number of control systems have been described. Here, we explore the emerging role of the ubiquitin‐proteasome system in monitoring and maintaining membrane lipid composition. We focus (...) on the ER‐resident RNF145 E3 ubiquitin ligase, its role in regulating adiponectin receptor 2 (ADIPOR2), its lipid hydrolase substrate, and the broader implications for understanding the homeostatic processes that fine‐tune cellular membrane composition. (shrink)

“Probably Peirce’s best-known works are the first two articles in a series of six that originally were collectively entitled Illustrations of the Logic of Science and published in Popular Science Monthly from November 1877 through August 1878. The first is entitled ‘The Fixation of Belief’ and the second is entitled ‘How to Make Our Ideas Clear.’ In the first of these papers Peirce defended, in a manner consistent with not accepting naive realism, the superiority of the scientific method over other (...) methods of overcoming doubt and ‘fixing belief.’” — Robert Burch, “Charles Sanders Peirce,” entry in the Stanford Encyclopedia of Philosophy (2021 revision) -/- “Pragmatist epistemologies often explore how we can carry out inquiries in a self-controlled and fruitful way. (Where much analytic epistemology centres around the concept of knowledge, considered as an idealised end-point of human thought, pragmatist epistemology centres around the concept of inquiry, considered as the process of knowledge-seeking and how we can improve it.) So pragmatists often provide rich accounts of the capacities or virtues that we must possess in order to inquire well, and the rules or guiding principles that we should adopt. A canonical account is Peirce’s classic early paper ‘The Fixation of Belief‘. Here Peirce states that inquiry is a struggle to replace doubt with “settled belief“, and that the only method of inquiry that can make sense of the fact that at least some of us are disturbed by inconsistent beliefs, and will subsequently reflect upon which methods of fixing belief are correct is the Method of Science, which draws on the Pragmatic Maxim described above. This contrasts with three other methods of fixing belief: i) refusing to consider evidence contrary to one’s favored beliefs (the Method of Tenacity), ii) accepting an institution’s dictates (the Method of Authority), iii) developing the most rationally coherent or elegant-seeming belief-set (the A Priori Method).“ — Catherine Legg, “Pragmatism,” entry in the Stanford Encyclopedia of Philosophy (2021 revision). (shrink)

According to most accounts of trust, you can only trust other people (or groups of people). To trust is to think that another has goodwill, or something to that effect. I sketch a different form of trust: the unquestioning attitude. What it is to trust, in this sense, is to settle one’s mind about something, to stop questioning it. To trust is to rely on a resource while suspending deliberation over its reliability. Trust lowers the barrier of monitoring, challenging, checking, (...) and questioning. Trust sets up open pipelines between yourself and parts of the external world. Trust permits external resources to have a similar relationship to one as one’s internal cognitive faculties. This creates efficiency, but at the price of exquisite vulnerability. We must trust in this way because we are cognitively limited beings in a cognitively overwhelming world. Crucially, we can hold the unquestioning attitude towards objects and technologies. When I trust my climbing rope, I stop worrying about its reliability. When I trust my online calendaring system, I simply go to the events indicated, without question. But, one might worry, how could one ever hold such a normatively loaded attitude as trust towards mere objects? How could it ever make sense to feel betrayed by an object? Trust is our engine for expanding and outsourcing our agency — for binding external processes into our practical selves. Thus, we can be betrayed by our smartphones in the same way that we can be betrayed by our memory. When we trust, we try to make something a part of our agency, and we are betrayed when our part lets us down. To unquestioningly trust something is to let it in—to attempt to bring it inside one’s practical functioning. This suggests a new form of gullibility: agential gullibility, which occurs when agents too hastily and carelessly integrate external resources into their own agency. (shrink)

Value capture occurs when an agent’s values are rich and subtle; they enter a social environment that presents simplified — typically quantified — versions of those values; and those simplified articulations come to dominate their practical reasoning. Examples include becoming motivated by FitBit’s step counts, Twitter Likes and Re-tweets, citation rates, ranked lists of best schools, and Grade Point Averages. We are vulnerable to value capture because of the competitive advantage that such crisp and clear expressions of value have in (...) our private reasoning and our public justification. There is, however, a price. In value capture, we take a central component of our autonomy — our ongoing deliberation over the exact articulation of our values — and we outsource it. And the metrics to which we outsource usually engineered for the interests of some external force, like a large-scale institution’s interest in cross-contextual comprehensibility and quick aggregability. That outsourcing cuts off one of the key benefits to personal deliberation. In value capture, we no longer adjust our values and their articulations in light of own rich experience of the world. Our values should often be carefully tailored to our particular selves or our small-scale communities, but in value capture, we buy our values off the rack. In some cases – like decreasing CO2 emissions – the costs of non-tailored values are outweighed by the benefit of precise collective coordination. In other cases, like in our aesthetic lives, they are not. This suggests that we should want different values suited to different scales. We should want value federalism. Some values are perhaps best pursued at the largest-scale level, others at smaller scales. The problem occurs when we exhibit an excess preference for the largest-scale values – when we consistently let the universal metrics swamp our quieter interests. (shrink)

Although the importance of measuring and reporting the social and environmental impact of organisational action is increasingly well recognised by both organisations and society at large, existing approaches to impact measurement are still far from being universally accepted. In this context, the stakeholder dynamics within the nascent field of impact investing demonstrate the complexity of resolving potentially differing perspectives on key impact measurement issues such as materiality. This paper argues, from an organisational perspective, that such arenas of contestation can be (...) conceptualised in terms of social justice. Specifically, we draw upon Sen’s notions of ‘arrangement and realisation’ to explore the dynamics of contestation across a range of stakeholders concerning materiality judgements to suggest that such ‘arrangements’ may lead to suboptimal impact outcomes as ‘realisations.’ Our analysis of the nature of materiality contestations in impact measurement reveals the conflicts, tensions and paradoxes evident in this field of action. Empirically, we examine data drawn from 19 cases and 33 interviews. The analysis suggests three arenas of contestation around the materiality of impact measurement: the power dynamics between economically powerful investors and objectified investees; the conflicts between materiality norms and standards; and the interactions between all stakeholders with differing motivations towards radical or incremental materiality. Building upon this analysis, we then discuss how arenas of contested materiality may be mediated by drawing upon Sen’s notions of transcending the individual interests of the invested parties for the greater good via processes of contextualisation and case-specificity. (shrink)

The genomes of vertebrates, flies, and nematodes contain highly conserved noncoding elements (CNEs). CNEs cluster around genes that regulate development, and where tested, they can act as transcriptional enhancers. Within an animal group CNEs are the most conserved sequences but between groups they are normally diverged beyond recognition. Alternative CNEs are, however, associated with an overlapping set of genes that control development in all animals. Here, we discuss the evidence that CNEs are part of the core gene regulatory networks (GRNs) (...) that specify alternative animal body plans. The major animal groups arose >550 million years ago. We propose that the cis‐regulatory inputs identified by CNEs arose during the “re‐wiring” of regulatory interactions that occurred during early animal evolution. Consequently, different animal groups, with different core GRNs, contain alternative sets of CNEs. Due to the subsequent stability of animal body plans, these core regulatory sequences have been evolving in parallel under strong purifying selection in different animal groups. (shrink)

Recent conversation has blurred two very different social epistemic phenomena: echo chambers and epistemic bubbles. Members of epistemic bubbles merely lack exposure to relevant information and arguments. Members of echo chambers, on the other hand, have been brought to systematically distrust all outside sources. In epistemic bubbles, other voices are not heard; in echo chambers, other voices are actively undermined. It is crucial to keep these phenomena distinct. First, echo chambers can explain the post-truth phenomena in a way that epistemic (...) bubbles cannot. Second, each type of structure requires a distinct intervention. Mere exposure to evidence can shatter an epistemic bubble, but may actually reinforce an echo chamber. Finally, echo chambers are much harder to escape. Once in their grip, an agent may act with epistemic virtue, but social context will pervert those actions. Escape from an echo chamber may require a radical rebooting of one's belief system. (shrink)

In recent years, historians have rediscovered the religious dimensions of the Enlightenment. This volume offers a thorough reappraisal of the so-called “Catholic Enlightenment” as a transnational Enlightenment movement. This Catholic Enlightenment was at once ultramontane and conciliarist, sometimes moderate but often surprisingly radical, with participants active throughout Europe in universities, seminaries, salons, and the periodical press._ In _Enlightenment and Catholicism in Europe: A Transnational History_, the contributors, primarily European scholars, provide intellectual biographies of twenty Catholic Enlightenment figures across eighteenth-century Europe, (...) many of them little known in English-language scholarship on the Enlightenment and pre-revolutionary eras. These figures represent not only familiar French intellectuals of the Catholic Enlightenment but also Iberian, Italian, English, Polish, and German thinkers. The essays focus on the intellectual and cultural factors influencing the lives and works of their subjects, revealing the often global networks of intellectual sociability and reading that united them both to the Catholic Enlightenment and to eighteenth-century policies and projects. The volume, whose purpose is to advance the understanding of a transnational "Catholic Enlightenment," will be a reliable reference for historians, theologians, and scholars working in religious studies. "This is a compelling collection on an important subject. Its transnational and biographical approach helps one to see eighteenth-century Catholicism and the Enlightenment itself in fresh and interesting ways." — Darrin M. McMahon, Florida State University_. (shrink)

This essay confronts Ray Brassier’s vindication of nihilism with other two important but frequently underexamined philosophical attempts to overcome nihilism: Hans Jonas’ and Keiji Nishitani’s. By putting these different takes on nihilism into dialogue, it explores some blind spots in Brassier’s position, as well as some of the practical consequences, for our current planetary situation, of undertaking a radical divorce between the normative and the natural that results from his radical nihilism. The article opts for a more moderate acceptance and (...) eventual self-overcoming of nihilism, according to which, even if natural entities are indifferent to human reasons and meanings, this does not entail that nature is bereft of a human-independent normative dimension. In other words, the essay argues that care must be taken not to confuse criticisms of an anthropocentric conception of reasons and meanings with the belief that meaning is completely absent from the natural world. Thus, the central contention of the article is that, given our current climate and ecological catastrophe, one of the most pressing tasks of contemporary philosophy is to understand normativity in non-anthropocentric ways, so that humans are no longer considered as the only entities that respond to normativity. Such an attitude conceives humans as estranged normative creatures amidst a meaningless, indifferent natural world, toward which they would have no ethical responsibilities. The essay finishes by suggesting ways in which to develop an account that does not fall into this ethical vacuum. (shrink)

This paper attempts an interpretation of Everett''s relative state formulation of quantum mechanics that avoids the commitment to new metaphysical entities like worlds or minds. Starting from Everett''s quantum mechanical model of an observer, it is argued that an observer''s belief to be in an eigenstate of the measurement (corresponding to the observation of a well-defined measurement outcome) is consistent with the fact that she objectively is in a superposition of such states. Subjective states corresponding to such beliefs are constructed. (...) From an analysis of these subjective states and their dynamics it is argued that Everett''s pure wave mechanics is subjectively consistent with von Neumann''s classical formulation of quantum mechanics. It follows from the argument that the objective state of a system is in principle unobservable. Nevertheless, an adequate concept of empirical reality can be constructed. (shrink)

In his celebrated masterpiece, Symposium, Plato imagines a high-society dinner-party in Athens in 416 BC at which the guests - including the comic poet Aristophanes and, of course, Plato's mentor Socrates - each deliver a short speech in praise of love. The sequence of dazzling speeches culminates in Socrates' famous account of the views of Diotima, a prophetess who taught him that love is our means of trying to attain goodness. And then into the party bursts the drunken Alcibiades, the (...) most popular and notorious Athenian of the time, who insists on praising Socrates himself rather than love, and gives us a brilliant sketch of this enigmatic character. The power, humour, and pathos of Plato's creation engages the reader on every page. This new translation is complemented by full explanatory notes and an illuminating introduction. (shrink)

It is widely agreed that protestant scholasticism influenced Kant’s thinking on the question of Divine Providence. But the nature and extent of that influence have never been explored in detail. This is the scholarly lacuna the present volume seeks to fill.

This paper attempts an interpretation of Everett's relative state formulation of quantum mechanics that avoids the commitment to new metaphysical entities like ‘worlds’ or ‘minds’. Starting from Everett's quantum mechanical model of an observer, it is argued that an observer's belief to be in an eigenstate of the measurement (corresponding to the observation of a well-defined measurement outcome) is consistent with the fact that she objectively is in a superposition of such states. Subjective states corresponding to such beliefs are constructed. (...) From an analysis of these subjective states and their dynamics it is argued that Everett's pure wave mechanics is subjectively consistent with von Neumann's classical formulation of quantum mechanics. It follows from the argument that the objective state of a system is in principle unobservable. Nevertheless, an adequate concept of empirical reality can be constructed. (shrink)

"This edition, which replaces the original Loeb edition..., offers text, translation, and annotation that are fully current with modern scholarship"--Front flap of dust jacket, volume 1.

This book present the first comprehensive overview of the Catholic Enlightenment in Europe by a group of leading international scholars.

This book present the first comprehensive overview of the Catholic Enlightenment in Europe by a group of leading international scholars.