With the recent advent of systems biology, developmental biology is taking a new turn. Attempts to create a ‘digital embryo’ are prominent among systems approaches. At the heart of these systems-based endeavours, variously described as ‘in vivoimaging’, ‘live imaging’ or ‘in totorepresentation’, are visualization techniques that allow researchers to image whole, live embryos at cellular resolution over time. Ultimately, the aim of the visualizations is to build a computer model of embryogenesis. This article examines the role of such visualization techniques (...) in the building of a computational model, focusing, in particular, on the cinematographic character of these representations. It asks how the animated representation of development may change the biological understanding of embryogenesis. By situating the animations of the digital embryo within the iconography of developmental biology, it brings to light the inextricably entwined, yet shifting, borders between the animated, the living and the computational. (shrink)

Over the course of the last three decades, computer simulations have become a major tool of doing science and engaging with the world, not least in an effort to predict and intervene in a future to come. Born in the context of the Second World War and the discipline of physics, simulations have long spread into most diverse fields of enquiry and technological application. This paper introduces a topical collection focussing on simulations in the life sciences. Echoing the current state (...) of tinkering, fast developments, segmentation of knowledge and interdisciplinary collaboration, and in an effort to bridge the science-humanities divide, the contributors to this collection come from multiple disciplinary backgrounds, including information studies, cognitive sciences, philosophy and biology. The ambiguous character of simulations, their cutting across scientific disciplines, analysis and prediction, understanding and doing, gave rise to their success in contemporary life sciences and has been the object of much scientific debate. One of the main aims of this topical collection, by contrast, is to call into question the assumption of an obvious use and easy transfer of methods between fields of knowledge as diverse as, e.g. physics and biology. The collection presents historical case studies from various biological sub-fields. The articles study how simulations are used and the ways they contribute specifically to our understanding of life. Taking up Sergio Sismondo’s description of simulations as “compromises” and “glue”, they also critically engage with the question of what exactly the life sciences have been gluing together over the last two decades. (shrink)

Morphogenesis is one of the fundamental processes of developing life. Gastrulation, especially, marks a period of major translocations and bustling rearrangements of cells that give rise to the three germ layers. It was also one of the earliest fields in biology where cell movement and behaviour in living specimens were investigated. This article examines scientific attempts to understand gastrulation from the point of view of cells in motion. It argues that the study of morphogenesis in the twentieth century faced a (...) major dilemma, both epistemological and pictorial: representing form and understanding movement are mutually exclusive, as are understanding form and representing movement. The article follows various ways of modelling, imaging, and simulating gastrular processes, from the early twentieth century to present-day systems biology. The first section examines the tactile modelling of shape changes, the second cell cinematography, mainly the pioneering work of the German embryologists Friedrich Kopsch and Ernst Ludwig Gräper in the 1920s but also a series of classic, yet not widely known, studies of the 1960s. The third section deals with the changes that computer simulation and live-cell imaging introduced to the modelling of shape change and the study of cell movement at the turn of the twenty-first century. Although live-cell imaging promises to experiment upon and represent the living body simultaneously, I argue that the new visuals are an obstacle rather than a solution to the puzzle of understanding cell motion. (shrink)

What is the nature of the compulsion to life writing? How does the elongated project of writing a life change as it shifts moments and locales, and why do others respond so directly as readers of stories that are so specific and particular? Janina Bauman is known in English-speaking cultures for two books, Winter in the Morning and A Dream of Belonging. The first covers her girlhood in the Warsaw ghetto, and escape; the second, more fictionalized, deals with the (...) period leading up to exile from Poland after 1968. Janina Bauman spent 20 years of her life working in Polish film. This article reflects on the process of coming to autobiography, and making sense of the writing process and the reception process. (shrink)

Since their arrival in Europe in the Middle Ages the Gypsies have suffered from discrimination on the grounds of racial prejudice. In the 20th century the NAZI doctrine lead to Porrajmos - the Gypsy Holocaust. In the post-war communist countries, Gypsies were forced to give up their traditional ways of life and become productive. Persecution of Gypsies - those who stayed in the post-communist countries and those who migrated to the West - continued in Europe after the big changes of (...) 1989 and up to the present time. (shrink)

Recent discussions on corporate citizenship highlight the new political role of corporations in society by arguing that corporations increasingly act as quasi-governmental actors and take on what hitherto had originally been governmental tasks. By examining political and sociological citizenship theories, the authors show that such a corporate engagement can be explained by a changing conception of corporate citizens from corporate bourgeois to corporate citoyen. As an intermediate actor in society, the corporate citoyen assumes co-responsibilities for social and civic affairs and (...) actively collaborates with fellow citizens beyond governmental regulation. This change raises the question of how such corporate civic engagement can be aligned with public policy regulations and how corporate activities can be integrated into the democratic regime. To clarify the mode of CC contributions to society, the authors will apply the tenet of subsidiarity as a governing principle which allows for specifying corporations’ tasks as intermediate actors in society. By referring to the renewed European Union strategy for Corporate Social Responsibility, the authors show how such a subsidiary corporate-governmental task-sharing can be organized. (shrink)

The purpose of this article is to provide a general overview of the work of Wanda Jakubowska, the first Polish, female film director to gain national and international recognition. Her career spanned over 50 years, in which she directed 14 full-length feature films, thus being the longest working film director in the history of Polish cinema. She was also one of the highest profile filmmakers to join the Polish communist party after the Second World War and in subsequent years (...) represented the ‘party line’ among her fellow film-makers, and lobbied the party on behalf of the cinema industry. The article looks at style, ideology and the most important themes of Jakubowska’s work. Its focus is on her films about concentration camps and about contemporary Poland. The article also attempts to establish whether and to what degree Jakubowska was a feminist. (shrink)

How will the Holocaust be remembered as its survivors disappear? In this article Janina Bauman reflects upon her own work on the Holocaust in the context of the Holocaust's broader reception. She offers her own views about the genre with reference to contemporary documents and testimonials, secondary work, scholarly work, fiction and film. These observations and stories all circulate around her own 1986 landmark text, Winter in the Morning.

Insight is a cognitive feature that is usually regarded as being generated by the neocortex and being present only in humans and possibly some closely related primates. In this essay we show that especially corvids display behavioral skills within the domains of object permanence, episodic memory, theory of mind, and tool use/causal reasoning that are insightful. These similarities between humans and corvids at the behavioral level are probably the result of a convergent evolution. Similarly, the telencephalic structures involved in higher (...) cognitive functions in both species show a high degree of similarity, although the forebrain of birds has no cortex-like lamination. The neural substrate for insight-related cognitive functions in mammals and birds is thus not necessarily based on a laminated cortical structure but can be generated by differently organized forebrains. Hence, neither is insight restricted to mammals, as predicted from a “scala naturae”, nor is the laminated cortex a prerequisite for the highest cognitive functions. (shrink)

The first part deals with the problem of the external form of ostensive definition. It is concluded that the definition statement is not complete. The proper form of this statement is not a sentence, but a sentential function, namely a sentential function of the type: ``Π x [N(x)=x is in the respect R and in the degree D such as A, B... and not such as K, L...]" where "N" stands for the term being defined. Thus the ostensive definition informs (...) about the criteria of applicability of the defined term in a partial way only, and the rest must be supplied by the addressee for whom the given definition was destined. In the second part the conditions are analysed on which depends the possibility of solving that problem, and consequently the conditions on which depend the informational value and the efficacy of ostensive definition. The concluding remarks deal with the properties of the terms introduced by the ostensive method. (shrink)

It is a study of the discursive construction of high achievers’ identities in American culture. A corpus of 100 commencement speeches delivered during 2016 and 2017 graduation ceremonies in American universities has been used to analyse how commencement speakers, as a rule highly successful individuals, construct their identities through discourse. Besides celebrating academic achievements, one of the communicative purposes of the commencement speech is giving the graduates advice for the future. It has been investigated how the speakers legitimize their qualifications (...) as a role model and the source of life wisdom. Due to the specificity of the discourse to be investigated, based on the foundations of American ethos of hard work and drive for success, Critical Discourse Analysis has been chosen as a methodological approach which can most adequately help analyze the discursive formation of identity. As the discourse to be analyzed is agentive discourse, culture-specific both in its form and content, I have decided to combine Critical Discourse Analysis with cultural studies. (shrink)

The article discusses work ethos in American ceremonial discourse addressed to the young entering adult life. Its aim is to investigate whether the Protestant work ethic still pervades the American thinking about work. Through a qualitative analysis of the corpus of 100 randomly selected commencement addresses delivered during 2016 and 2017 graduation ceremonies in American universities, it is shown how work-related topics are employed by the speakers celebrating the graduates’ academic achievements and providing them with advice for the future. The (...) Discourse-Historical Approach, committed to Critical Discourse Analysis, has been chosen as a methodological approach, integrating the interpretation of discourses and texts with sociological and historical research, studies on narration, stylistics, rhetoric and argumentation theory. As the discourse to be analyzed is culture-specific, I have decided to combine the Discourse-Historical Approach with Cultural Studies. (shrink)

Notwithstanding the expectations related to the ‘invasion’ of human rights into the field of healthcare, the complexity of this field raises some problematic questions about the applicability of such a legal instrument. The present paper analyses the possible limits to the content of the core right to healthcare. These limits are discussed through the examination of two normative pillars of health law: the right to individual self-determination (or the principle of individual autonomy) and the right to healthcare itself. The authors (...) conclude that in the context of the scarcity of resources the effectiveness of the guarantees of the right to healthcare will depend on the narrowing of the concept of the right by choosing the biomedical definition of health as the basis. (shrink)