The choroid plexuses (CPs) are involved in the most-basic aspects of neural function including maintaining the extracellular milieu of the brain by actively modulating chemical exchange between the CSF and brain parenchyma, surveying the chemical and immunological status of the brain, detoxifying the brain, secreting a nutritive “cocktail” of polypeptides and participating in repair processes following trauma. This diversity of functions may mean that even modest changes in the CP can have far-reaching effects. Indeed, changes in the anatomy and physiology (...) of the CP have been linked to aging and several CNS diseases. It is also possible that replacing diseased or transplanting healthy CP might be useful for treating acute and chronic brain diseases. This review focuses on the wide-ranging and under-appreciated functions of the CP, alterations of these functions in aging and neurodegeneration, and recent demonstrations of the therapeutic potential of transplanted CP for neural trauma. BioEssays 27:262–274, 2005. © 2005 Wiley Periodicals, Inc. (shrink)

The climate change mitigation effort is being translated into several actions and discourses that make collateral benefits and their rationale increasingly relevant for sustainability, in such a way that they are now a constant part of the political agenda. Taking a broader and consensual perspective, co-benefits are considered here to be emerging advantages of implementing measures to lower greenhouse gases. Starting with the analysis of policy documents referring to two European urban transportation strategies, the emergent co-benefits are problematized and discussed (...) to better understand their moral aspect. Further ethical reflection is conducted after an analysis of some unintended consequences of the co-benefits rationale arising from the examples. The discussion focuses primarily on the challenges of an integrative moral justification for co-benefits and also for their role in the climate change mitigation effort. We also discuss the limitations of the current normative models that frame a co-benefits rationale, both from a moral viewpoint and in relation to the overall climate change mitigation strategy. In this article, we propose the concepts of well-being and freedom, as portrayed by the Capability Approach, as possible guiding notions for the moral and social evaluation of goodness of these emergent benefits as well as their rationale. Additionally, some preliminary conclusions are drawn regarding the potential of the presented concepts to support climate change mitigation action. Finally, we outline a scenario where the Capability Approach is the moral guideline for a co-benefits rationale and illustrates its potential in terms of enhancing climate change mitigation strategy. (shrink)

In this paper I will present textual evidence of a close link between Catullus’ Poems 16 and 5, by exploring a few formal elements that critics have ignored so far. Moreover, after some remarks on the position of Poem 16 inside the libellus, I will discuss the interpretation of this composition, assuming that it refers to 5 (and also 7, by extension) and adding to some scholars’ observations a few of my own.

The rapid growth of human population and associated industrialisation creates strains on resources and climate. One way to understand the impact of human activity is to quantify the total environmental pressures by measuring the ‘footprint’. Footprints account for the total direct and/or indirect effects of a product or a consumption activity, which may be related to e.g. carbon, water or land use, and can be seen as a proxy for environmental responsibility. Footprints shape climate and resource debates, especially concerning environmental (...) strategies. However, in general, footprints hold a dichotomous producer–consumer perspective that is not unanimously accepted. In addition, the current footprinting system transmits a simplistic message about environmental responsibility that taints the justice debate and jeopardises the validity of policies based on them. Consequently, it is crucial to question who is accountable for adverse environmental effects. It is also critical to investigate how the methodological characteristics of footprints shape and affect the efficacy of policies on climate and natural resources. This article examines these challenges, focusing on negative justice and policy implications resulting from assigning environmental responsibility to a sole agent. The article proposes, and morally justifies, the development of a footprinting method that includes justice parameters in an attempt to render fair results that are more meaningful for environmental action. The second objective is to establish the potential of this new framework to promote environmental responsibility and justice while facilitating policymaking. The suggested justice elements aim at turning footprints into a concrete environmental policy instrument framed under the value of environmental fairness. (shrink)

In 1987, the Brundtland Commission urged nations to improve present conditions without compromising the ability of future generations to meet their needs. Against the background of this appeal for sustainable development, there is a call for intergenerational justice, under a sufficientarian framework. Despite their strong relation, we claim that, to some degree, intergenerational sufficientarianism disregards relevant sustainability notions. This neglect undermines intergenerational sufficientarianism in the context of sustainability, here operationalized as sustainable development. In response, we propose the concept of irreplaceable (...) goods as a necessary bridge between the two frameworks. Simultaneously, we stress the need for scholars to consider sufficientarianism as a valid alternative to egalitarianism for achieving resource justice. To harmonize intergenerational sufficientarianism and sustainability, we firstly delineate sustainability theoretical notions that influence fair distributive futures. Secondly, we incorporate those sustainability constraints into the conceptual background of intergenerational sufficientarianism. We also establish the concept of irreplaceable goods as a pivot and anchor for further theoretical development on the sufficient well-being of future generations. Finally, we discuss the implications of this concept in terms of expenditure and investment by contemporary people. With the proposed adjustments, we advocate that intergenerational sufficientarianism is a robust framework to deliver just futures. (shrink)

Writing from a scientifically and philosophically informed perspective, the authors provide a critical overview of the conceptual difficulties encountered in many current neuroscientific and psychological theories.

Resenhas dos seguintes livros: Scarlett Marton. Nietzsche e as mulheres: Figuras, imagens e tipos femininos. Autêntica, 2022; Marie-Frédérique Pellegrin. Pensées du corps et différences des sexes à l’époque moderne. ENS Éditions, 2020; e Ana Gabriela Colantoni; Georgia Cristina Amitrano; Carla Milani Damião (orgs.). Ensaios de filósofas brasileiras. Ape’Ku Editora, 2022.

O artigo parte de uma aproximação à sura 19 para problematizar a forma convencional de se compreenderem a formação do Corão e as origens do islã. Por uma análise rápida dos materiais e das fontes que mostram o texto mostra como as teorias tradicionais sobre o surgimento de ambos são inadequadas porque não consideram a dinâmica e a vitalidade da cultura, bem como o complexo quadro das tradições religiosas presentes no Oriente Médio dos tempos da Antiguidade tardia, especialmente aquelas que (...) de alguma forma poderiam ser nomeadas judias ou cristãs. E propõe que do interior daquilo que se costuma chamar judeu-cristianismo emergem tanto um quanto outro. (shrink)

O presente estudo pretende analisar a obra Cur Deus homo, de Santo Anselmo, a partir de uma perspectiva antropológica. Após examinar a peculiaridade do método e revisar seus argumentos fundamentais, será possível perceber que Anselmo revela uma perspectiva essencialmente boa da natureza humana, que, mesmo abalada, não sucumbe ao pecado original. A liberdade e o projeto amoroso do Logos originante fundamentam a concepção anselmiana em torno do homem e sua natureza. This study aims to analyze St. Anselm's Cur Deus Homo (...) from an anthropological perspective. After analyzing the method used in this work and reviewing its basic argumentation, it can be seen that Anselm reveals a perspective according to which human nature is essentially good. This nature, even when shaken, does not succumb to original sin. Freedom and the loving design of the originating Logos underlie the Anselmian conception of man and his nature. (shrink)

Com o fim do Império Romano, a estrutura educacional foi abalada. A religião cristã foi capaz de preservar a tradição da antiguidade. Pouco a pouco uma nova civilização vai surgindo, erguendo-se a partir de três bases: a cultura romana subsistente, o impacto dos bárbaros e a religião cristã. No reino dos francos, Carlos Magno faz renascer a cultura, através de sua aliança com a Igreja. Surgem novas escolas e há uma retomada das artes liberais; a dialética, particularmente, será a base (...) para a retomada dos debates filosóficos, mesmo inseridos em polêmicas teológicas, tais como a discussão em torno da predestinação divina que colocou em lados opostos Godescalco e Scoto Eriúgena. (shrink)

Resumo O presente artigo busca analisar uma das orações elaboradas por Anselmo de Aosta, mais precisamente, a Oração a São Nicolau, procurando mostrar como é possível encontrar, refletidos na prece, aspectos relevantes da produção filosófico-teológica do autor, sobretudo, em relação à situação do homem, marcado pelo pecado, uma vez que abandonou a retidão da vontade. Na prece, bem como em sua obra especulativa, Anselmo examina a situação do homem pecador, diante da graça e misericórdia divinas. Almejamos ressaltar a existência, na (...) obra anselmiana, de uma harmoniosa relação entre oração e trabalho especulativo, em conformidade com o ideal beneditino do ora et labora.This article analyzes one of the prayers of Anselm of Canterbury, namely, the Prayer to Saint Nicholas. We aim to show how it is possible to find relevant aspects of the author’s philosophical-theological output reflected in the prayer, mainly in relation to the situation of man, marked by sin, once rectitude and will are abandoned. In the prayer, as well as in his speculative work, Anselm examines the situation of sinful man in the face of divine grace and mercy. We highlight the existence in Anselm’s work of a harmonious relationship between prayer and speculation, in conformity with the Benedictine ideal of ora et labora. (shrink)

A recepção do pensamento greco-romano árabe e judaico pelo ocidente medieval.

Climate change mitigation effort is being translated into several actions and discourses that make collateral benefits and their rationale increasingly relevant for sustainability, in such a way that they are now a constant part of the political agenda. Taking a border and consensual perspective, co-benefits are considered here to be emerging advantages of the implementation of measures regarding the lowering of greenhouse gases.Departing from the analysis of policy documents referring to two European urban transportation strategies, the emergent co-benefits are problematized (...) and discussed to better understand their moral aspect. Further ethical reflection is conducted after an analysis of some unintended consequences of co-benefits rationale coming from the mentioned examples. The focus is primarily on the challenges of an integrative moral justification for co-benefits and also for their role in the climate change mitigation effort. We also discuss the limitations of the current normative models that frame co-benefits rationale, from a moral viewpoint and in relation to the overall climate change mitigation strategy.In this article, we propose the concepts of well-being and freedom, as portrayed by Capabilities Approach, as possible guiding notions for the moral and social evaluation of goodness of these emergent benefits and their rationale too. Additionally, some preliminary conclusions are drawn regarding the potential of the presented concepts to favour the climate change mitigation action. Finally, a scenario is drawn where Capabilities Approach is the moral guideline for co-benefits rationale showing this way its potential in terms of enhancing climate change mitigation strategy. (shrink)

Estabelecer uma cone çáo entre um pressuposto etico - viver a vida e um enunciado ontologico: uma vida em sua imanencia. Articular os conceitos filosoficos ao seu plano de imanencia. lnstaurar uma relaç áo inequivoca entre imanencia e vida filosofica em Gilles Deleuze. ' Palavras-chave: Imanencia/ vidal ontologia/ Deleuze.

O presente artigo quer investigar o problema do mal na perspectiva de Santo Anselmo, tomando como ponto de partida sua obra "De casu diaboli", onde o tema é abordado, a partir da íntima ligação entre mal e pecado. Ao enfocar o mal na perspectiva da queda diabólica, o Doutor Magnífico intenta mostrar a conexão entre vontade, liberdade e justiça. Sua preocupação é investigar o significado moral da má escolha, realizada por uma criatura racional e puramente espiritual, feita boa e para (...) ser boa. O pecado, consoante o autor, não está em almejar a felicidade, pois um tal desejo é dádiva divina; o mal praticado pelo anjo está, precisamente, em querer a felicidade fora da justiça, isto é, ao querer ser feliz, ele foi de encontro ao que ele deveria ser: quis ser semelhante a Deus, extrapolando a sua própria natureza, pois ele desejou algo que, enquanto criatura, não caberia a ele almejar. Este é o ponto de partida para analisar o mal e sua mais dramática consequência, o sofrimento. (shrink)

On taking Breviloquium as a guide, we can understand how St. Bonaventure analyses the issue of evil and its relation to sin. Man was created to be good and to live in a good world. By sinning, he interferes with the divine plan, establishing evil in the world. God, the first and most perfect principle, however, is perfect; then, He comes to man’s help so that he can overcome sin and evil. Upon reflecting on Philosophy and Theology, Bonaventure discusses the (...) issue of evil origin, transmission and breakthrough, pointing to man’s unique and affirmative role, as he has not lost his natural attraction to virtue; he is still able to do right. (shrink)

Resenha MILES, Jack. Religion as we know it. An Origin Story. Nova Iorque: Norton, 2020. 152p. ISBN: 978-1-324-00278-9.

A long-standing theme in discussion of perception and thought has been that our primary cognitive contact with individual objects and events in the world derives from our perceptual contact with them. When I look at a duck in front of me, I am not merely presented with the fact that there is at least one duck in the area, rather I seem to be presented withthisthing (as one might put it from my perspective) in front of me, which looks to (...) me to be a duck. Furthermore, such a perception would seem to put me in a position not merely to make the existential judgment that there is some duck or other present, but rather to make a singular, demonstrative judgment, that that is a duck. My grounds for an existential judgment in this case derives from my apprehension of the demonstrative thought and not vice versa. (shrink)

This book defends antitheodicism, arguing that theodicies, seeking to excuse God for evil and suffering in the world, fail to ethically acknowledge the victims of suffering. The authors argue for this view using literary and philosophical resources, commencing with Immanuel Kant's 1791 "Theodicy Essay" and its reading of the Book of Job. Three important twentieth century antitheodicist positions are explored, including "Jewish" post-Holocaust ethical antitheodicism, Wittgensteinian antitheodicism exemplified by D.Z. Phillips and pragmatist antitheodicism defended by William James. The authors argue (...) that these approaches to evil and suffering are fundamentally Kantian. Literary works such as Franz Kafka'sThe Trial, Samuel Beckett's Waiting for Godot, and George Orwell's Nineteen Eighty-Four, are examined in order to crucially advance the philosophical case for antitheodicism. (shrink)

In his last book, David Armstrong sets out his metaphysical system in a set of concise and lively chapters each dealing with one aspect of the world. He begins with the assumption that all that exists is the physical world of space-time. On this foundation he constructs a coherent metaphysical scheme that gives plausible answers to many of the great problems of metaphysics. He gives accounts of properties, relations, and particulars; laws of nature; modality; abstract objects such as numbers; and (...) time and mind. (shrink)

Is consciousness a purely physical phenomenon? Most contemporary philosophers and theorists hold that it is, and take this to be supported by modern science. But a significant minority endorse non-physicalist theories such as dualism, idealism and panpsychism, among other reasons because it may seem impossible to fully explain consciousness, or capture what it's like to be in conscious states (such as seeing red, or being in pain), in physical terms. This Element will introduce the main non-physicalist theories of consciousness and (...) explain the most important arguments for them, and consider how they each respond to the scientific and other arguments in support of physicalism. This title is also available as Open Access on Cambridge Core. (shrink)

Western democracy is now at a critical juncture. Some worry that power has been wrested from the people and placed in the hands of a small political elite. Others argue that the democratic system gives too much power to a populace that is largely ill-informed and easily swayed by demagogues. This classic study of democratic principles is thus now more relevant than ever. A renowned historian of antiquity and political philosophy, Sir M.I. Finley offers a comparative analysis of Greek and (...) modern conceptions of democracy. As he puts the ancient Greeks in dialogue with their contemporary counterparts, Finley tackles some of the most pressing issues of our day, including public apathy, partisanship, consensus politics, distrust of professional politicians, and the limits of free speech. Including three lectures that Finley delivered at Rutgers University, plus two additional essays that further illuminate his thinking, _Democracy Ancient and Modern _explores the dramatic differences between the close-knit civil society of the ancient Greeks and our own atomized mass societies. By mapping out democracy’s past and its present manifestations, this book helps us plot a course for democracy’s future. (shrink)

This book presents a collection of essays on institutional theory written by the German sociologist and Weber-expert M. Rainer Lepsius. Based on Weber's work, the author develops concepts of institutional theory, which he subsequently applies to topics such as National Socialism, democratization processes, German unification, and the institutionalization of the European Union. By showing how charismatic leadership can under certain circumstances threaten democratic structures and curtail individual freedoms, and by analyzing the structural and cultural conditions under which people develop trust (...) in political and social structures and ultimately come to support and comply with them, the author provides a sound analytical understanding of the development of democratic institutions and a democratic political culture. This collection of essays was edited, translated and commented on by Claus Wendt. (shrink)

The Ismaili Imam and Imamat -- Ethical foundations -- Tradition and modernity -- The ethos of modernism -- Pluralism and cosmopolitan ethics -- Cohesion within the Umma -- Islam and the West -- Cultivating and enabling environment -- Living the ethics of Islam -- Global convergence.

The socialist construction in Vietnam, aspect of human role.

The given is the state of a mind in its primary engagement with the world. A satisfactory epistemology—one, it turns out, that is foundationalist and includes a naïve realist view of perception—requires a certain account of the given. Moreover, knowledge based on the given requires both a particular view of the world itself and a heterodox account of judgment. These admittedly controversial claims are supported by basic ontological considerations. I begin, then, with two contradictory views of the world per se (...) and the structure one experiences. I draw out the consequences of these two views for what intentionality is. The two views yield incompatible accounts of the given. The definitive spontaneity of the one account, and passivity of the other, can be understood in terms of the structure (or lack thereof) in the given. In defense of the claim that a structured given is not an apt epistemic basis, I examine an attempt to found an epistemology on such an account in light of the so-called myth of the given. I maintain that the given, if it is to provide some justification for taking the world to be a particular way, must be unstructured. To support this, I first discuss a significant problem with traditional foundationalism. I then argue that a satisfactory (foundationalist) epistemology requires the rejection of the orthodox propositional view of judgment in favor of a non-propositional, reistic view. (shrink)

A violência contra a mulher é considerada mundialmente como um problema de saúde pública e a América Latina tem sido apontada como a região de maior incidência deste tipo de violação. Esta revisão sistemática objetivou investigar a produção científica latino-americana sobre serviços de atendimento à mulher vítima de violência que incluam psicólogos em suas equipes. Foram realizadas buscas nas bases de dados Scielo, Lilacs, e Portal Capes, com os descritores “violência contra a mulher”, “violência doméstica contra a mulher”, “psicologia”, “psicología”, (...) “violencia contra las mujeres”, “violencia doméstica contra la mujer”. Considerou-se apenas artigos publicados na América Latina, nos idiomas português e espanhol, durante os últimos 5 anos. No total, 10 estudos foram analisados na íntegra. Esta revisão permitiu constatar que ainda há lacunas na rede de atendimento, que dizem respeito não apenas à atuação do psicólogo, mas também às diferentes áreas que compõem as redes de acolhimento à mulher. (shrink)