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  1.  5
    Montreal Brain Injury Vision Screening Test for General Practitioners.Reza Abbas Farishta & Reza Farivar - 2022 - Frontiers in Human Neuroscience 16.
    Visual disturbances are amongst the most commonly reported symptoms after a traumatic brain injury despite vision testing being uncommon at initial clinical evaluation. TBI patients consistently present a wide range of visual complaints, including photophobia, double vision, blurred vision, and loss of vision which can detrimentally affect reading abilities, postural balance, and mobility. In most cases, especially in rural areas, visual disturbances of TBI would have to be diagnosed and assessed by primary care physicians, who lack the specialized training of (...)
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  2.  4
    Centromedian Nucleus of the Thalamus Deep Brain Stimulation for Genetic Generalized Epilepsy: A Case Report and Review of Literature.Shruti Agashe, David Burkholder, Keith Starnes, Jamie J. Van Gompel, Brian N. Lundstrom, Gregory A. Worrell & Nicholas M. Gregg - 2022 - Frontiers in Human Neuroscience 16.
    There is a paucity of treatment options for cognitively normal individuals with drug resistant genetic generalized epilepsy. Centromedian nucleus of the thalamus deep brain stimulation may be a viable treatment for GGE. Here, we present the case of a 27-year-old cognitively normal woman with drug resistant GGE, with childhood onset. Seizure semiology are absence seizures and generalized onset tonic clonic seizures. At baseline she had 4–8 GTC seizures per month and weekly absence seizures despite three antiseizure medications and vagus nerve (...)
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  3.  3
    Association of resting-state theta–gamma coupling with selective visual attention in children with tic disorders.Ji Seon Ahn, Kyungun Jhung, Jooyoung Oh, Jaeseok Heo, Jae-Jin Kim & Jin Young Park - 2022 - Frontiers in Human Neuroscience 16:1017703.
    A tic disorder (TD) is a neurodevelopmental disorder characterized by tics, which are repetitive movements and/or vocalizations that occur due to aberrant sensory gating. Its pathophysiology involves dysfunction in multiple parts of the cortico-striato-thalamo-cortical circuits. Spontaneous brain activity during the resting state can be used to evaluate the baseline brain state, and it is associated with various aspects of behavior and cognitive processes. Theta–gamma coupling (TGC) is an emerging technique for examining how neural networks process information through interactions. However, the (...)
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  4.  5
    Effects of three-dimension movie visual fatigue on cognitive performance and brain activity.Ryota Akagi, Hiroki Sato, Tatsuya Hirayama, Kosuke Hirata, Masahiro Kokubu & Soichi Ando - 2022 - Frontiers in Human Neuroscience 16:974406.
    To further develop three-dimensional (3D) applications, it is important to elucidate the negative effects of 3D applications on the human body and mind. Thus, this study investigated differences in the effects of visual fatigue on cognition and brain activity using visual and auditory tasks induced by watching a 1-h movie in two dimensions (2D) and 3D. Eighteen young men participated in this study. Two conditions were randomly performed for each participant on different days, namely, watching the 1-h movie on television (...)
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  5.  4
    The Effect of Pedaling at Different Cadence on Attentional Resources.Mayu Akaiwa, Koki Iwata, Hidekazu Saito, Eriko Shibata, Takeshi Sasaki & Kazuhiro Sugawara - 2022 - Frontiers in Human Neuroscience 16.
    We investigated the relationship between attentional resources and pedaling cadence using electroencephalography to measure P300 amplitudes and latencies. Twenty-five healthy volunteers performed the oddball task while pedaling on a stationary bike or relaxing. We set them four conditions, namely, performing only the oddball task, performing the oddball task while pedaling at optimal cadence, performing the oddball task while pedaling faster than optimal cadence, and performing the oddball task while pedaling slower than optimal cadence. P300 amplitudes at Cz and Pz electrodes (...)
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  6.  4
    The Outcome of Neurorehabilitation Efficacy and Management of Traumatic Brain Injury.Miyamoto Akira, Takata Yuichi, Ueda Tomotaka, Kubo Takaaki, Mori Kenichi & Miyamoto Chimi - 2022 - Frontiers in Human Neuroscience 16.
    For public health professionals, traumatic brain injury and its possible protracted repercussions are a significant source of worry. In opposed to patient neurorehabilitation with developed brain abnormalities of different etiologies, neurorehabilitation of affected persons has several distinct features. The clinical repercussions of the various types of TBI injuries will be discussed in detail in this paper. During severe TBI, the medical course frequently follows a familiar first sequence of coma, accompanied by disordered awareness, followed by agitation and forgetfulness, followed by (...)
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  7.  5
    Cognitive theories of autism based on the interactions between brain functional networks.Sarah Barzegari Alamdari, Masoumeh Sadeghi Damavandi, Mojtaba Zarei & Reza Khosrowabadi - 2022 - Frontiers in Human Neuroscience 16:828985.
    Cognitive functions are directly related to interactions between the brain's functional networks. This functional organization changes in the autism spectrum disorder (ASD). However, the heterogeneous nature of autism brings inconsistency in the findings, and specific pattern of changes based on the cognitive theories of ASD still requires to be well-understood. In this study, we hypothesized that the theory of mind (ToM), and the weak central coherence theory must follow an alteration pattern in the network level of functional interactions. The main (...)
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  8.  10
    Artifact characterization and mitigation techniques during concurrent sensing and stimulation using bidirectional deep brain stimulation platforms.Michaela E. Alarie, Nicole R. Provenza, Michelle Avendano-Ortega, Sarah A. McKay, Ayan S. Waite, Raissa K. Mathura, Jeffrey A. Herron, Sameer A. Sheth, David A. Borton & Wayne K. Goodman - 2022 - Frontiers in Human Neuroscience 16:1016379.
    Bidirectional deep brain stimulation (DBS) platforms have enabled a surge in hours of recordings in naturalistic environments, allowing further insight into neurological and psychiatric disease states. However, high amplitude, high frequency stimulation generates artifacts that contaminate neural signals and hinder our ability to interpret the data. This is especially true in psychiatric disorders, for which high amplitude stimulation is commonly applied to deep brain structures where the native neural activity is miniscule in comparison. Here, we characterized artifact sources in recordings (...)
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  9.  8
    Effect of Obesity on Arithmetic Processing in Preteens With High and Low Math Skills: An Event-Related Potentials Study.Graciela C. Alatorre-Cruz, Heather Downs, Darcy Hagood, Seth T. Sorensen, D. Keith Williams & Linda J. Larson-Prior - 2022 - Frontiers in Human Neuroscience 16.
    Preadolescence is an important period for the consolidation of certain arithmetic facts, and the development of problem-solving strategies. Obese subjects seem to have poorer academic performance in math than their normal-weight peers, suggesting a negative effect of obesity on math skills in critical developmental periods. To test this hypothesis, event-related potentials were collected during a delayed-verification math task using simple addition and subtraction problems in obese [above 95th body mass index percentile] and non-obese preteens with different levels of math skill; (...)
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  10.  3
    Age-related decrease in motor contribution to multisensory reaction times in primary school children.Areej A. Alhamdan, Melanie J. Murphy & Sheila G. Crewther - 2022 - Frontiers in Human Neuroscience 16:967081.
    Traditional measurement of multisensory facilitation in tasks such as speeded motor reaction tasks (MRT) consistently show age-related improvement during early childhood. However, the extent to which motor function increases with age and hence contribute to multisensory motor reaction times in young children has seldom been examined. Thus, we aimed to investigate the contribution of motor development to measures of multisensory (auditory, visual, and audiovisual) and visuomotor processing tasks in three young school age groups of children (n = 69) aged (5−6, (...)
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  11.  1
    Self-Perception and the Relation to Actual Driving Abilities for Individuals With Visual Field Loss.Jan Andersson, Tomas Bro & Timo Lajunen - 2022 - Frontiers in Human Neuroscience 16.
    BackgroundIn Sweden, individuals with visual field loss have their driving license withdrawn. The literature clearly indicates that individuals with VFL are unsafe drivers on a group level. However, many drivers with VFL can be safe on an individual level. The literature also suggests that self-perception, beliefs, and insights of one’s own capabilities are related to driving performance. This study had three aims: To investigate self-perceived driving capability ratings for individuals with VFL; to compare these ratings between groups with different medical (...)
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  12.  6
    The Increasing Effect of Interoception on Brain Frontal Responsiveness During a Socially Framed Motor Synchronization Task.Laura Angioletti & Michela Balconi - 2022 - Frontiers in Human Neuroscience 16.
    This research explored the effect of explicit Interoceptive Attentiveness manipulation on hemodynamic brain correlates during a task involving interpersonal motor coordination framed with a social goal. Participants performed a task requiring interpersonal movement synchrony with and without a social framing in both explicit IA and control conditions. Functional Near-Infrared Spectroscopy was used to record oxygenated and deoxygenated hemoglobin changes during the tasks. According to the results, the prefrontal cortex, which is involved in high-order social cognition and interpersonal relations processing, was (...)
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  13.  2
    Neurofeedback in patients with frontal brain lesions: A randomized, controlled double-blind trial.Christine Annaheim, Kerstin Hug, Caroline Stumm, Maya Messerli, Yves Simon & Margret Hund-Georgiadis - 2022 - Frontiers in Human Neuroscience 16:979723.
    BackgroundFrontal brain dysfunction is a major challenge in neurorehabilitation. Neurofeedback (NF), as an EEG-based brain training method, is currently applied in a wide spectrum of mental health conditions, including traumatic brain injury.ObjectiveThis study aimed to explore the capacity of Infra-Low Frequency Neurofeedback (ILF-NF) to promote the recovery of brain function in patients with frontal brain injury.Materials and methodsTwenty patients hospitalized at a neurorehabilitation clinic in Switzerland with recently acquired, frontal and optionally other brain lesions were randomized to either receive NF (...)
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  14.  2
    Math difficulties in attention deficit hyperactivity disorder do not originate from the visual number sense.Giovanni Anobile, Mariaelisa Bartoli, Gabriele Masi, Annalisa Tacchi & Francesca Tinelli - 2022 - Frontiers in Human Neuroscience 16:949391.
    There is ample evidence from literature and clinical practice indicating mathematical difficulties in individuals with ADHD, even when there is no concomitant diagnosis of developmental dyscalculia. What factors underlie these difficulties is still an open question. Research on dyscalculia and neurotypical development suggests visual perception of numerosity (the number sense) as a building block for math learning. Participants with lower numerosity estimation thresholds (higher precision) are often those with higher math capabilities. Strangely, the role of numerosity perception in math skills (...)
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  15.  9
    Functional and Prognostic Assessment in Comatose Patients: A Study Using Somatosensory Evoked Potentials.Andrea Victoria Arciniegas-Villanueva, Eva María Fernández-Diaz, Emilio Gonzalez-Garcìa, Javier Sancho-Pelluz, David Mansilla-Lozano & Tomás Segura - 2022 - Frontiers in Human Neuroscience 16.
    AimThe functional prognosis of patients after coma following either cardiac arrest or acute structural brain injury is often uncertain. These patients are associated with high mortality and disability. N20 and N70 somatosensory evoked potentials are used to predict prognosis. We evaluated the utility of SSEP as an early indicator of long-term prognosis in these patients.MethodsThis was a retrospective cohort study of patients admitted to the intensive care unit with a diagnosis of coma after CA or ABI. An SSEP study was (...)
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  16.  5
    Editorial: How to improve neuroscience education for the public and for a multi-professional audience in different parts of the globe.Analía Arévalo, Valeria Abusamra & Guilherme Lepski - 2022 - Frontiers in Human Neuroscience 16.
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  17.  4
    What Does the General Public Know (or Not) About Neuroscience? Effects of Age, Region and Profession in Brazil.Analía Arévalo, Estefania Simoes, Fernanda Petinati & Guilherme Lepski - 2022 - Frontiers in Human Neuroscience 16.
    The field of Neuroscience has experienced a growing interest in recent decades, which has led to an exponential growth in the amount of related information made available online as well as the market for Neuroscience-related courses. While this type of knowledge can be greatly beneficial to people working in science, health and education, it can also benefit individuals in other areas. For example, neuroscience knowledge can help people from all fields better understand and critique information about new discoveries or products, (...)
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  18.  13
    Infra-Low Frequency Neurofeedback in Tension-Type Headache: A Cross-Over Sham-Controlled Study.Galina A. Arina, Olga R. Dobrushina, Elizaveta T. Shvetsova, Ekaterina D. Osina, Georgy A. Meshkov, Guzel A. Aziatskaya, Alexandra K. Trofimova, Inga N. Efremova, Sergey E. Martunov & Valentina V. Nikolaeva - 2022 - Frontiers in Human Neuroscience 16.
    Primary headaches are highly prevalent and represent a major cause of disability in young adults. Neurofeedback is increasingly used in the treatment of chronic pain; however, there are few studies investigating its efficacy in patients with headaches. We report the results of a cross-over sham-controlled study on the efficacy of neurofeedback in the prophylactic treatment of tension-type headache. Participants received ten sessions of infra-low frequency electroencephalographic neurofeedback and ten sessions of sham-neurofeedback, with the order of treatments being randomized. The study (...)
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  19.  5
    Editorial: Psychology and Neuropsychology of Perception, Action, and Cognition.Jane E. Aspell, Els Ortibus & Silvio Ionta - 2022 - Frontiers in Human Neuroscience 16.
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  20.  6
    Editorial: Sensing the World Through Predictions and Errors.Ryszard Auksztulewicz, Marta I. Garrido, Manuel S. Malmierca, Alessandro Tavano, Juanita Todd & István Winkler - 2022 - Frontiers in Human Neuroscience 16.
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  21.  5
    A multimodal approach for the ecological investigation of sustained attention: A pilot study.Keren Avirame, Noga Gshur, Reut Komemi & Lena Lipskaya-Velikovsky - 2022 - Frontiers in Human Neuroscience 16:971314.
    Natural fluctuations in sustained attention can lead to attentional failures in everyday tasks and even dangerous incidences. These fluctuations depend on personal factors, as well as task characteristics. So far, our understanding of sustained attention is partly due to the common usage of laboratory setups and tasks, and the complex interplay between behavior and brain activity. The focus of the current study was thus to test the feasibility of applying a single-channel wireless EEG to monitor patterns of sustained attention during (...)
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  22.  2
    Skill-learning by observation-training with patients after traumatic brain injury.Einat Avraham, Yaron Sacher, Rinatia Maaravi-Hesseg, Avi Karni & Ravid Doron - 2022 - Frontiers in Human Neuroscience 16.
    Traumatic brain injury is a major cause of death and disability in Western society, and often results in functional and neuropsychological abnormalities. Memory impairment is one of the most significant cognitive implications after TBI. In the current study we investigated procedural memory acquisition by observational training in TBI patients. It was previously found that while practicing a new motor skill, patients engage in all three phases of skill learning–fast acquisition, between-session consolidation, and long-term retention, though their pattern of learning is (...)
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  23.  6
    A Preliminary Study of the Efficacy of Transcranial Direct Current Stimulation in Trigeminal Neuralgia.Babak Babakhani, Narges Hoseini Tabatabaei, Kost Elisevich, Narges Sadeghbeigi, Mojtaba Barzegar, Neda Mohammadi Mobarakeh, Fatemeh Eyvazi, Zahra Khazaeipour, Arman Taheri & Mohammad-Reza Nazem-Zadeh - 2022 - Frontiers in Human Neuroscience 16.
    The purpose of this study is to assess the efficacy of transcranial direct current stimulation in patients with treatment-refractory trigeminal neuralgia and examine the utility of neuroimaging methods in identifying markers of such efficacy. Six patients with classical TN refractory to maximal medical treatment, underwent tDCS. All patients underwent pre- and posttreatment functional magnetic resonance imaging during block-design tasks as well as single-shell diffusion MRI acquisition. The precise locations of tDCS electrodes were identified by neuronavigation. Five therapeutic tDCS sessions were (...)
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  24.  5
    Multimodal Evidence of Atypical Processing of Eye Gaze and Facial Emotion in Children With Autistic Traits.Shadi Bagherzadeh-Azbari, Gilbert Ka Bo Lau, Guang Ouyang, Changsong Zhou, Andrea Hildebrandt, Werner Sommer & Ming Lui - 2022 - Frontiers in Human Neuroscience 16.
    According to the shared signal hypothesis the impact of facial expressions on emotion processing partially depends on whether the gaze is directed toward or away from the observer. In autism spectrum disorder several aspects of face processing have been found to be atypical, including attention to eye gaze and the identification of emotional expressions. However, there is little research on how gaze direction affects emotional expression processing in typically developing individuals and in those with ASD. This question is investigated here (...)
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  25.  2
    Circadian Variation of Migraine Attack Onset Affects fMRI Brain Response to Fearful Faces.Daniel Baksa, Edina Szabo, Natalia Kocsel, Attila Galambos, Andrea Edit Edes, Dorottya Pap, Terezia Zsombok, Mate Magyar, Kinga Gecse, Dora Dobos, Lajos Rudolf Kozak, Gyorgy Bagdy, Gyongyi Kokonyei & Gabriella Juhasz - 2022 - Frontiers in Human Neuroscience 16:842426.
    BackgroundPrevious studies suggested a circadian variation of migraine attack onset, although, with contradictory results – possibly because of the existence of migraine subgroups with different circadian attack onset peaks. Migraine is primarily a brain disorder, and if the diversity in daily distribution of migraine attack onset reflects an important aspect of migraine, it may also associate with interictal brain activity. Our goal was to assess brain activity differences in episodic migraine subgroups who were classified according to their typical circadian peak (...)
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  26.  3
    Editorial: Effects of Physical Exercise on Brain and Cognitive Functioning.Soledad Ballesteros, Laura Piccardi & Joshua Oon Soo Goh - 2022 - Frontiers in Human Neuroscience 16.
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  27.  5
    Electrophysiological indices of pain expectation abnormalities in fibromyalgia patients.Paloma Barjola, Irene Peláez, David Ferrera, José Luis González-Gutiérrez, Lilian Velasco, Cecilia Peñacoba-Puente, Almudena López-López, Roberto Fernandes-Magalhaes & Francisco Mercado - 2022 - Frontiers in Human Neuroscience 16:943976.
    Fibromyalgia is a chronic pain syndrome characterized by dysfunctional processing of nociceptive stimulation. Neuroimaging studies have pointed out that pain-related network functioning seems to be altered in these patients. It is thought that this clinical symptomatology may be maintained or even strengthened because of an enhanced expectancy for painful stimuli or its forthcoming appearance. However, neural electrophysiological correlates associated with such attentional mechanisms have been scarcely explored. In the current study, expectancy processes of upcoming laser stimulation (painful and non-painful) and (...)
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  28.  5
    Neural Correlates of Executed Compared to Imagined Writing and Drawing Movements: A Functional Magnetic Resonance Imaging Study.Alexander Baumann, Inken Tödt, Arne Knutzen, Carl Alexander Gless, Oliver Granert, Stephan Wolff, Christian Marquardt, Jos S. Becktepe, Sönke Peters, Karsten Witt & Kirsten E. Zeuner - 2022 - Frontiers in Human Neuroscience 16.
    ObjectiveIn this study we used functional magnetic resonance imaging to investigate whether motor imagery of handwriting and circle drawing activates a similar handwriting network as writing and drawing itself.MethodsEighteen healthy right-handed participants wrote the German word “Wellen” and drew continuously circles in a sitting and lying position to capture kinematic handwriting parameters such as velocity, pressure and regularity of hand movements. Afterward, they performed the same tasks during fMRI in a MI and an executed condition.ResultsThe kinematic analysis revealed a general (...)
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  29.  4
    Infra-Low Frequency Neurofeedback: A Systematic Mixed Studies Review.Fabian Bazzana, Sarah Finzi, Giulia Di Fini & Fabio Veglia - 2022 - Frontiers in Human Neuroscience 16.
    IntroductionNeurofeedback training is increasingly applied as a therapeutic tool in a variety of disorders, with growing scientific and clinical interest in the last two decades. Different Neurofeedback approaches have been developed over time, so it is now important to be able to distinguish between them and investigate the effectiveness and efficiency characteristics of each specific protocol. In this study we intend to examine the effects of Neurofeedback based on slow brain activity, the so-called Infra-Low Frequency training a recently developed methodology (...)
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  30.  3
    The Proactive Synergy Between Action Observation and Execution in the Acquisition of New Motor Skills.Maria Chiara Bazzini, Arturo Nuara, Emilia Scalona, Doriana De Marco, Giacomo Rizzolatti, Pietro Avanzini & Maddalena Fabbri-Destro - 2022 - Frontiers in Human Neuroscience 16:793849.
    Motor learning can be defined as a process that leads to relatively permanent changes in motor behavior through repeated interactions with the environment. Different strategies can be adopted to achieve motor learning: movements can be overtly practiced leading to an amelioration of motor performance; alternatively, covert strategies (e.g., action observation) can promote neuroplastic changes in the motor system even in the absence of real movement execution. However, whether a training regularly alternating action observation and execution (i.e., Action Observation Training, AOT) (...)
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  31.  2
    The Neural Representation of a Repeated Standard Stimulus in Dyslexia.Sara D. Beach, Ola Ozernov-Palchik, Sidney C. May, Tracy M. Centanni, Tyler K. Perrachione, Dimitrios Pantazis & John D. E. Gabrieli - 2022 - Frontiers in Human Neuroscience 16.
    The neural representation of a repeated stimulus is the standard against which a deviant stimulus is measured in the brain, giving rise to the well-known mismatch response. It has been suggested that individuals with dyslexia have poor implicit memory for recently repeated stimuli, such as the train of standards in an oddball paradigm. Here, we examined how the neural representation of a standard emerges over repetitions, asking whether there is less sensitivity to repetition and/or less accrual of “standardness” over successive (...)
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  32.  13
    Responsive Neurostimulation Targeting the Anterior, Centromedian and Pulvinar Thalamic Nuclei and the Detection of Electrographic Seizures in Pediatric and Young Adult Patients.Cameron P. Beaudreault, Carrie R. Muh, Alexandria Naftchi, Eris Spirollari, Ankita Das, Sima Vazquez, Vishad V. Sukul, Philip J. Overby, Michael E. Tobias, Patricia E. McGoldrick & Steven M. Wolf - 2022 - Frontiers in Human Neuroscience 16.
    BackgroundResponsive neurostimulation has been utilized as a treatment for intractable epilepsy. The RNS System delivers stimulation in response to detected abnormal activity, via leads covering the seizure foci, in response to detections of predefined epileptiform activity with the goal of decreasing seizure frequency and severity. While thalamic leads are often implanted in combination with cortical strip leads, implantation and stimulation with bilateral thalamic leads alone is less common, and the ability to detect electrographic seizures using RNS System thalamic leads is (...)
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  33.  3
    A scoping review of electroencephalographic (EEG) markers for tracking neurophysiological changes and predicting outcomes in substance use disorder treatment.Tarik S. Bel-Bahar, Anam A. Khan, Riaz B. Shaik & Muhammad A. Parvaz - 2022 - Frontiers in Human Neuroscience 16:995534.
    Substance use disorders (SUDs) constitute a growing global health crisis, yet many limitations and challenges exist in SUD treatment research, including the lack of objective brain-based markers for tracking treatment outcomes. Electroencephalography (EEG) is a neurophysiological technique for measuring brain activity, and although much is known about EEG activity in acute and chronic substance use, knowledge regarding EEG in relation to abstinence and treatment outcomes is sparse. We performed a scoping review of longitudinal and pre-post treatment EEG studies that explored (...)
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  34.  4
    Editorial: Cognitive and Motor Control Based on Brain-Computer Interfaces for Improving the Health and Well-Being in Older Age.Abdelkader Nasreddine Belkacem, Tiago H. Falk, Takufumi Yanagisawa & Christoph Guger - 2022 - Frontiers in Human Neuroscience 16.
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  35.  13
    Effects of virtual reality-based feedback on neurofeedback training performance—A sham-controlled study.Lisa M. Berger, Guilherme Wood & Silvia E. Kober - 2022 - Frontiers in Human Neuroscience 16.
    Electroencephalography-neurofeedback has become a valuable tool in the field of psychology, e.g., to improve cognitive function. Nevertheless, a large percentage of NF users seem to be unable to control their own brain activation. Therefore, the aim of this study was to examine whether a different kind of visual feedback could positively influence NF performance after one training session. Virtual reality seems to have beneficial training effects and has already been reported to increase motivational training aspects. In the present study, we (...)
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  36.  3
    Neural Correlates of Attachment Representation in Patients With Borderline Personality Disorder Using a Personalized Functional Magnet Resonance Imaging Task.Dorothee Bernheim, Anna Buchheim, Martin Domin, Renate Mentel & Martin Lotze - 2022 - Frontiers in Human Neuroscience 16.
    BackgroundFear of abandonment and aloneness play a key role in the clinical understanding interpersonal and attachment-specific problems in patients with borderline personality disorder and has been investigated in previous functional Magnet Resonance Imaging studies. The aim of the present study was to examine how different aspects of attachment representations are processed in BPD, by using for the first time an fMRI attachment paradigm including personalized core sentences from the participants’ own attachment stories. We hypothesized that BPD patients would show increased (...)
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  37.  2
    Linking Signal Relevancy and Intensity in Predictive Tactile Suppression.Marie C. Beyvers, Lindsey E. Fraser & Katja Fiehler - 2022 - Frontiers in Human Neuroscience 16.
    Predictable somatosensory feedback leads to a reduction in tactile sensitivity. This phenomenon, called tactile suppression, relies on a mechanism that uses an efference copy of motor commands to help select relevant aspects of incoming sensory signals. We investigated whether tactile suppression is modulated by the task-relevancy of the predicted consequences of movement and the intensity of related somatosensory feedback signals. Participants reached to a target region in the air in front of a screen; visual or tactile feedback indicated the reach (...)
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  38.  6
    Temporally Local Tactile Codes Can Be Stored in Working Memory.Arindam Bhattacharjee & Cornelius Schwarz - 2022 - Frontiers in Human Neuroscience 16.
    Tactile exploration often involves sequential touches interspersed with stimulus-free durations. Whereas it is obvious that texture-related perceptual variables, irrespective of the encoding strategy, must be stored in memory for comparison, it is rather unclear which of those variables are held in memory. There are two established variables—“intensity” and “frequency”, which are “temporally global” variables because of the long stimulus integration interval required to average the signal or derive spectral components, respectively; on the other hand, a recently established third contender is (...)
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  39.  5
    The Acceptability, Feasibility, and Utility of Portable Electroencephalography to Study Resting-State Neurophysiology in Rural Communities.Supriya Bhavnani, Dhanya Parameshwaran, Kamal Kant Sharma, Debarati Mukherjee, Gauri Divan, Vikram Patel & Tara C. Thiagarajan - 2022 - Frontiers in Human Neuroscience 16.
    Electroencephalography provides a non-invasive means to advancing our understanding of the development and function of the brain. However, the majority of the world’s population residing in low and middle income countries has historically been limited from contributing to, and thereby benefiting from, such neurophysiological research, due to lack of scalable validated methods of EEG data collection. In this study, we establish a standard operating protocol to collect approximately 3 min each of eyes-open and eyes-closed resting-state EEG data using a low-cost (...)
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  40.  8
    Complexity changes in functional state dynamics suggest focal connectivity reductions.David Sutherland Blair, Carles Soriano-Mas, Joana Cabral, Pedro Moreira, Pedro Morgado & Gustavo Deco - 2022 - Frontiers in Human Neuroscience 16:958706.
    The past two decades have seen an explosion in the methods and directions of neuroscience research. Along with many others, complexity research has rapidly gained traction as both an independent research field and a valuable subdiscipline in computational neuroscience. In the past decade alone, several studies have suggested that psychiatric disorders affect the spatiotemporal complexity of both global and region-specific brain activity (Liu et al., 2013; Adhikari et al., 2017; Li et al., 2018). However, many of these studies have not (...)
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  41.  4
    Inhibitory Control and the Structural Parcelation of the Right Inferior Frontal Gyrus.Rune Boen, Liisa Raud & Rene J. Huster - 2022 - Frontiers in Human Neuroscience 16.
    The right inferior frontal gyrus has most strongly, although not exclusively, been associated with response inhibition, not least based on covariations of behavioral performance measures and local gray matter characteristics. However, the white matter microstructure of the rIFG as well as its connectivity has been less in focus, especially when it comes to the consideration of potential subdivisions within this area. The present study reconstructed the structural connections of the three main subregions of the rIFG using diffusion tensor imaging, and (...)
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  42.  3
    Transcranial direct current stimulation alters sensorimotor modulation during cognitive representation of movement.Gaia Bonassi, Giovanna Lagravinese, Martina Putzolu, Alessandro Botta, Marco Bove, Elisa Pelosin & Laura Avanzino - 2022 - Frontiers in Human Neuroscience 16:862013.
    We recently demonstrated, by means of short latency afferent inhibition (SAI), that before an imagined movement, during the reaction time (RT), SAI decreases only in the movement-related muscle (sensorimotor modulation) and that a correlation exists between sensorimotor modulation and motor imagery (MI) ability. Excitatory anodal transcranial direct current stimulation (a-tDCS) on M1 could enhance the MI outcome; however, mechanisms of action are not completely known. Here, we assessed if a-tDCS on M1 prior to an MI task could affect sensorimotor modulation. (...)
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  43.  9
    The Multidisciplinary Guidelines for Diagnosis and Referral in Cerebral Visual Impairment.Frouke N. Boonstra, Daniëlle G. M. Bosch, Christiaan J. A. Geldof, Catharina Stellingwerf & Giorgio Porro - 2022 - Frontiers in Human Neuroscience 16.
    IntroductionCerebral visual impairment is an important cause of visual impairment in western countries. Perinatal hypoxic-ischemic damage is the most frequent cause of CVI but CVI can also be the result of a genetic disorder. The majority of children with CVI have cerebral palsy and/or developmental delay. Early diagnosis is crucial; however, there is a need for consensus on evidence based diagnostic tools and referral criteria. The aim of this study is to develop guidelines for diagnosis and referral in CVI according (...)
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  44.  2
    Up right, not right up: Primacy of verticality in both language and movement.Véronique Boulenger, Livio Finos, Eric Koun, Roméo Salemme, Clément Desoche & Alice C. Roy - 2022 - Frontiers in Human Neuroscience 16:981330.
    When describing motion along both the horizontal and vertical axes, languages from different families express the elements encoding verticality before those coding for horizontality (e.g., going up right instead of right up). In light of the motor grounding of language, the present study investigated whether the prevalence of verticality in Path expression also governs the trajectory of arm biological movements. Using a 3D virtual-reality setting, we tracked the kinematics of hand pointing movements in five spatial directions, two of which implied (...)
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  45.  9
    Does Motor Symptoms Asymmetry Predict Motor Outcome of Subthalamic Deep Brain Stimulation in Parkinson's Disease Patients?Francesco Bove, Francesco Cavallieri, Anna Castrioto, Sara Meoni, Emmanuelle Schmitt, Amélie Bichon, Eugénie Lhommée, Pierre Pélissier, Andrea Kistner, Eric Chevrier, Eric Seigneuret, Stephan Chabardès, Franco Valzania, Valerie Fraix & Elena Moro - 2022 - Frontiers in Human Neuroscience 16.
    BackgroundIn Parkinson's disease, the side of motor symptoms onset may influence disease progression, with a faster motor symptom progression in patients with left side lateralization. Moreover, worse neuropsychological outcomes after subthalamic nucleus deep brain stimulation have been described in patients with predominantly left-sided motor symptoms. The objective of this study was to evaluate if the body side of motor symptoms onset may predict motor outcome of bilateral STN-DBS.MethodsThis retrospective study included all consecutive PD patients treated with bilateral STN-DBS at Grenoble (...)
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  46.  6
    Stimulation Parameters Used During Repetitive Transcranial Magnetic Stimulation for Motor Recovery and Corticospinal Excitability Modulation in SCI: A Scoping Review.Nabila Brihmat, Didier Allexandre, Soha Saleh, Jian Zhong, Guang H. Yue & Gail F. Forrest - 2022 - Frontiers in Human Neuroscience 16.
    There is a growing interest in non-invasive stimulation interventions as treatment strategies to improve functional outcomes and recovery after spinal cord injury. Repetitive transcranial magnetic stimulation is a neuromodulatory intervention which has the potential to reinforce the residual spinal and supraspinal pathways and induce plasticity. Recent reviews have highlighted the therapeutic potential and the beneficial effects of rTMS on motor function, spasticity, and corticospinal excitability modulation in SCI individuals. For this scoping review, we focus on the stimulation parameters used in (...)
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  47.  6
    Does Prefrontal Glutamate Index Cognitive Changes in Parkinson’s Disease?Isabelle Buard, Natalie Lopez-Esquibel, Finnuella J. Carey, Mark S. Brown, Luis D. Medina, Eugene Kronberg, Christine S. Martin, Sarah Rogers, Samantha K. Holden, Michael R. Greher & Benzi M. Kluger - 2022 - Frontiers in Human Neuroscience 16.
    IntroductionCognitive impairment is a highly prevalent non-motor feature of Parkinson’s disease. A better understanding of the underlying pathophysiology may help in identifying therapeutic targets to prevent or treat dementia. This study sought to identify metabolic alterations in the prefrontal cortex, a key region for cognitive functioning that has been implicated in cognitive dysfunction in PD.MethodsProton Magnetic Resonance Spectroscopy was used to investigate metabolic changes in the PFC of a cohort of cognitively normal individuals without PD, as well as PD participants (...)
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  48.  3
    Editorial: Neuroscience of human attachment volume II.Anna Buchheim, Carol George & Harald Gündel - 2022 - Frontiers in Human Neuroscience 16.
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  49.  3
    Identifying Risk and Resilience Factors in the Intergenerational Cycle of Maltreatment: Results From the TRANS-GEN Study Investigating the Effects of Maternal Attachment and Social Support on Child Attachment and Cardiovascular Stress Physiology.Anna Buchheim, Ute Ziegenhain, Heinz Kindler, Christiane Waller, Harald Gündel, Alexander Karabatsiakis & Jörg Fegert - 2022 - Frontiers in Human Neuroscience 16.
    IntroductionChildhood maltreatment is a developmental risk factor and can negatively influence later psychological functioning, health, and development in the next generation. A comprehensive understanding of the biopsychosocial underpinnings of CM transmission would allow to identify protective factors that could disrupt the intergenerational CM risk cycle. This study examined the consequences of maternal CM and the effects of psychosocial and biological resilience factors on child attachment and stress-regulatory development using a prospective trans-disciplinary approach.MethodsMother-child dyads participated shortly after parturition, after 3 months, (...)
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  50.  2
    Mixed Neuropathologies, Neural Motor Resilience and Target Discovery for Therapies of Late-Life Motor Impairment.Aron S. Buchman & David A. Bennett - 2022 - Frontiers in Human Neuroscience 16.
    By age 85, most adults manifest some degree of motor impairment. However, in most individuals a specific etiology for motor decline and treatment to modify its inexorable progression cannot be identified. Recent clinical-pathologic studies provide evidence that mixed-brain pathologies are commonly associated with late-life motor impairment. Yet, while nearly all older adults show some degree of accumulation of Alzheimer’s disease and related dementias pathologies, the extent to which these pathologies contribute to motor decline varies widely from person to person. Slower (...)
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  51.  7
    Differential Diagnosis of Akinetic Mutism and Disorder of Consciousness Using Diffusion Tensor Tractography: A Case Report.Dong Hyun Byun & Sung Ho Jang - 2022 - Frontiers in Human Neuroscience 16.
    This paper presents a case in whom a differential diagnosis of akinetic mutism with a disorder of consciousness was made using diffusion tensor tractography. A 69-year-old female patient was diagnosed with subarachnoid hemorrhage, intraventricular hemorrhage, and intracerebral hemorrhage produced by the subarachnoid hemorrhage. She exhibited impaired consciousness with a Coma Recovery Scale-Revised score of 13 until 1 month after onset. Her impaired consciousness recovered slowly to a normal state according to the Coma Recovery Scale-Revised at 7 weeks after onset. On (...)
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  52.  3
    The influence of one-time biofeedback electromyography session on the firing order in the pelvic floor muscle contraction in pregnant woman–A randomized controlled trial.Monika Błudnicka, Magdalena Piernicka, Jakub Kortas, Damian Bojar, Barbara Duda-Biernacka & Anna Szumilewicz - 2022 - Frontiers in Human Neuroscience 16:944792.
    Many women are initially unable to contract the pelvic floor muscles (PFMs) properly, activating other muscle groups before, or instead of, PFM. Numerous authors have proved that biofeedback can be an ideal tool supporting learning of the PFM contraction. However, there is currently a lack of scientific data on how many biofeedback sessions are necessary in this educational process. In this study we aimed at assessing the effects of one-time electromyography (EMG) biofeedback session on the order in which PFM are (...)
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  53.  4
    Corrigendum: Yoga, Meditation and Mind-Body Health: Increased BDNF, Cortisol Awakening Response, and Altered Inflammatory Marker Expression After a 3-Month Yoga and Meditation Retreat.B. Rael Cahn, Matthew S. Goodman, Christine T. Peterson, Raj Maturi & Paul J. Mills - 2022 - Frontiers in Human Neuroscience 16.
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  54.  5
    Effect of Exercise on the Cognitive Function of Older Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.Yi-Hui Cai, Zi Wang, Le-Yi Feng & Guo-Xin Ni - 2022 - Frontiers in Human Neuroscience 16.
    BackgroundAging and type 2 diabetes mellitus are important risk factors for the development of cognitive deterioration and dementia. The objective of this research was to investigate the effects of an exercise intervention on cognitive function in older T2DM patients.MethodsEight literature databases were searched from inception to 20 January 2022. The researchers examined randomized controlled trials that evaluated the impact of exercise on the cognitive performance of older T2DM patients. The Cochrane risk-of-bias tool for RCTs was used to assess each study. (...)
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  55.  4
    Identifying and validating subtypes of Parkinson's disease based on multimodal MRI data via hierarchical clustering analysis.Kaiqiang Cao, Huize Pang, Hongmei Yu, Yingmei Li, Miaoran Guo, Yu Liu & Guoguang Fan - 2022 - Frontiers in Human Neuroscience 16.
    ObjectiveWe wished to explore Parkinson's disease subtypes by clustering analysis based on the multimodal magnetic resonance imaging indices amplitude of low-frequency fluctuation and gray matter volume. Then, we analyzed the differences between PD subtypes.MethodsEighty-six PD patients and 44 healthy controls were recruited. We extracted ALFF and GMV according to the Anatomical Automatic Labeling partition using Data Processing and Analysis for Brain Imaging software. The Ward linkage method was used for hierarchical clustering analysis. DPABI was employed to compare differences in ALFF (...)
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  56.  5
    Correlation Between Resting Theta Power and Cognitive Performance in Patients With Schizophrenia.Yanxiang Cao, Chuanliang Han, Xing Peng, Ziyao Su, Gan Liu, Yixi Xie, Yiting Zhang, Jun Liu, Pei Zhang, Wen Dong, Michel Gao, Sha Sha & Xixi Zhao - 2022 - Frontiers in Human Neuroscience 16.
    ObjectiveSchizophrenia is a mental disorder that is characterized by progressive cognitive impairment. Objective measures of cognitive function may provide reliable neurobiomarkers for patients with schizophrenia. The goal of the current work is to explore the correlation between resting theta power and cognitive performance in patients with schizophrenia.MethodsTwenty-two patients with schizophrenia and 23 age-, sex-, and education-matched healthy controls were included in this study. The MATRICS Consensus Cognitive Battery was used for cognitive evaluation and the Positive and Negative Syndrome Scale for (...)
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  57.  5
    Editorial: Mechanisms Underlying the Interplay Between Cognition and Motor Control: From Bench to Bedside.Thomas Carsten, Gerard Derosiere, Maximilian J. Wessel, Friedhelm C. Hummel & Julie Duque - 2022 - Frontiers in Human Neuroscience 16.
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  58.  3
    Software Bug Detection Causes a Shift From Bottom-Up to Top-Down Effective Connectivity Involving the Insula Within the Error-Monitoring Network.Joao Castelhano, Isabel C. Duarte, Ricardo Couceiro, Julio Medeiros, Joao Duraes, Sónia Afonso, Henrique Madeira & Miguel Castelo-Branco - 2022 - Frontiers in Human Neuroscience 16.
    The neural correlates of software programming skills have been the target of an increasing number of studies in the past few years. Those studies focused on error-monitoring during software code inspection. Others have studied task-related cognitive load as measured by distinct neurophysiological measures. Most studies addressed only syntax errors. However, a recent functional MRI study suggested a pivotal role of the insula during error-monitoring when challenging deep-level analysis of code inspection was required. This raised the hypothesis that the insula is (...)
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  59.  6
    Molecular and Brain Volume Changes Following Aerobic Exercise, Cognitive and Combined Training in Physically Inactive Healthy Late-Middle-Aged Adults: The Projecte Moviment Randomized Controlled Trial.Alba Castells-Sánchez, Francesca Roig-Coll, Rosalía Dacosta-Aguayo, Noemí Lamonja-Vicente, Pere Torán-Monserrat, Guillem Pera, Alberto García-Molina, José Maria Tormos, Pilar Montero-Alía, Antonio Heras-Tébar, Juan José Soriano-Raya, Cynthia Cáceres, Sira Domènech, Marc Via, Kirk I. Erickson & Maria Mataró - 2022 - Frontiers in Human Neuroscience 16.
    Behavioral interventions have shown promising neuroprotective effects, but the cascade of molecular, brain and behavioral changes involved in these benefits remains poorly understood. Projecte Moviment is a 12-week multi-domain, single-blind, proof-of-concept randomized controlled trial examining the cognitive effect and underlying mechanisms of an aerobic exercise, computerized cognitive training and a combined groups compared to a waitlist control group. Adherence was > 80% for 82/109 participants recruited. In this study we report intervention-related changes in plasma biomarkers and structural-MRI and how they (...)
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  60.  20
    Brain Computer Interfaces and Communication Disabilities: Ethical, Legal, and Social Aspects of Decoding Speech From the Brain.Jennifer A. Chandler, Kiah I. Van der Loos, Susan Boehnke, Jonas S. Beaudry, Daniel Z. Buchman & Judy Illes - 2022 - Frontiers in Human Neuroscience 16:841035.
    A brain-computer interface technology that can decode the neural signals associated with attempted but unarticulated speech could offer a future efficient means of communication for people with severe motor impairments. Recent demonstrations have validated this approach. Here we assume that it will be possible in future to decode imagined (i.e., attempted but unarticulated) speech in people with severe motor impairments, and we consider the characteristics that could maximize the social utility of a BCI for communication. As a social interaction, communication (...)
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  61.  3
    The Differentiation of Self-Motion From External Motion Is a Prerequisite for Postural Control: A Narrative Review of Visual-Vestibular Interaction.Shikha Chaudhary, Nicola Saywell & Denise Taylor - 2022 - Frontiers in Human Neuroscience 16.
    The visual system is a source of sensory information that perceives environmental stimuli and interacts with other sensory systems to generate visual and postural responses to maintain postural stability. Although the three sensory systems; the visual, vestibular, and somatosensory systems work concurrently to maintain postural control, the visual and vestibular system interaction is vital to differentiate self-motion from external motion to maintain postural stability. The visual system influences postural control playing a key role in perceiving information required for this differentiation. (...)
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  62.  6
    Disrupted Brain Structural Network Connection in de novo Parkinson's Disease With Rapid Eye Movement Sleep Behavior Disorder.Amei Chen, Yuting Li, Zhaoxiu Wang, Junxiang Huang, Xiuhang Ruan, Xiaofang Cheng, Xiaofei Huang, Dan Liang, Dandan Chen & Xinhua Wei - 2022 - Frontiers in Human Neuroscience 16.
    ObjectiveTo explore alterations in white matter network topology in de novo Parkinson's disease patients with rapid eye movement sleep behavior disorder.Materials and MethodsThis study included 171 de novo PD patients and 73 healthy controls recruited from the Parkinson's Progression Markers Initiative database. The patients were divided into two groups, PD with probable RBD and PD without probable RBD, according to the RBD screening questionnaire. Individual structural network of brain was constructed based on deterministic fiber tracking and analyses were performed using (...)
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  63.  4
    Cognitive Control Deficits in Children With Subthreshold Attention-Deficit/Hyperactivity Disorder.Caiqi Chen, Zhuangyang Li, Xiqin Liu, Yongling Pan & Tingting Wu - 2022 - Frontiers in Human Neuroscience 16.
    Subthreshold Attention-Deficit/Hyperactivity Disorder is defined as a neurobiological condition with some core inattentive or hyperactive/impulsive symptoms of ADHD which do not meet the full diagnosis clinically. Although it has been well documented that deficits in cognitive control, a high-level cognitive construct closely related to attention, are frequently found among children with ADHD, whether subthreshold ADHD is also associated with similar deficits remains unclear. In this study, we examined the attention functions and the cognitive control capacity in children with ADHD, those (...)
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  64.  2
    Research Hotspots and Trends of Exercise on Parkinson's Disease: A Global Bibliometric Analysis From 2012 to 2021.Ji-Wei Chen, Shu-Hao Du, Tian-Cong Chen & Kun Zhu - 2022 - Frontiers in Human Neuroscience 16.
    BackgroundParkinson's disease is a chronic neurodegenerative disease, which can be alleviated in drug treatment, but with evident side effects. At the same time, increasing evidence shows that exercise can significantly improve the symptoms of patients with Parkinson's disease, with an effect that cannot be achieved by drug treatment. The related research on exercise on Parkinson's disease increases rapidly with the passage of time. However, the research analysis on Parkinson's disease by means of bibliometrics is rare. The purpose of this study (...)
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  65.  3
    Visually Perceived Negative Emotion Enhances Mismatch Negativity but Fails to Compensate for Age-Related Impairments.Jiali Chen, Xiaomin Huang, Xianglong Wang, Xuefei Zhang, Sishi Liu, Junqin Ma, Yuanqiu Huang, Anli Tang & Wen Wu - 2022 - Frontiers in Human Neuroscience 16.
    Objective: Automatic detection of auditory stimuli, represented by the mismatch negativity, facilitates rapid processing of salient stimuli in the environment. The amplitude of MMN declines with ageing. However, whether automatic detection of auditory stimuli is affected by visually perceived negative emotions with normal ageing remains unclear. We aimed to evaluate how fearful facial expressions affect the MMN amplitude under ageing.Methods: We used a modified oddball paradigm to analyze the amplitude of N100 and MMN in 22 young adults and 21 middle-aged (...)
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  66.  5
    Brain Structure as a Correlate of Odor Identification and Cognition in Type 2 Diabetes.Mimi Chen, Jie Wang, Shanlei Zhou, Cun Zhang, Datong Deng, Fujun Liu, Wei Luo, Jiajia Zhu & Yongqiang Yu - 2022 - Frontiers in Human Neuroscience 16.
    Background: It has been reported that type 2 diabetes is associated with olfactory identification impairments and cognitive decline. However, the relationship between OI impairments and cognitive decline is largely unknown in T2DM patients.Methods: Sixty-eight T2DM patients and 68 healthy controls underwent 3D-T1 MRI scans, olfactory and cognitive assessments. The cortical thickness of olfaction-related brain regions, olfactory and cognitive scores were compared between groups. Correlation analyses were carried out among cognition, olfaction, and cortical thickness of olfaction-related brain regions.Results: First, the cognitive (...)
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  67.  9
    Subthalamic high-beta oscillation informs the outcome of deep brain stimulation in patients with Parkinson's disease.Po-Lin Chen, Yi-Chieh Chen, Po-Hsun Tu, Tzu-Chi Liu, Min-Chi Chen, Hau-Tieng Wu, Mun-Chun Yeap, Chih-Hua Yeh, Chin-Song Lu & Chiung-Chu Chen - 2022 - Frontiers in Human Neuroscience 16:958521.
    BackgroundThe therapeutic effect of deep brain stimulation (DBS) of the subthalamic nucleus (STN) for Parkinson's disease (PD) is related to the modulation of pathological neural activities, particularly the synchronization in the β band (13–35 Hz). However, whether the local β activity in the STN region can directly predict the stimulation outcome remains unclear.ObjectiveWe tested the hypothesis that low-β (13–20 Hz) and/or high-β (20–35 Hz) band activities recorded from the STN region can predict DBS efficacy.MethodsLocal field potentials (LFPs) were recorded in (...)
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  68.  6
    Effect of Anesthetics on Functional Connectivity of Developing Brain.Xu Chen, Xuemei Zheng, Jianghui Cai, Xiao Yang, Yonghong Lin, Mengjun Wu, Xiaofan Deng & Yong G. Peng - 2022 - Frontiers in Human Neuroscience 16.
    The potential anesthetic neurotoxicity on the neonate is an important focus of research investigation in the field of pediatric anesthesiology. It is essential to understand how these anesthetics may affect the development and growth of neonatal immature and vulnerable brains. Functional magnetic resonance imaging has suggested that using anesthetics result in reduced functional connectivity may consider as core sequence for the neurotoxicity and neurodegenerative changes in the developed brain. Anesthetics either directly impact the primary structures and functions of the brain (...)
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  69.  1
    A brain-like classification method for computed tomography images based on adaptive feature matching dual-source domain heterogeneous transfer learning.Yehang Chen & Xiangmeng Chen - 2022 - Frontiers in Human Neuroscience 16:1019564.
    Transfer learning can improve the robustness of deep learning in the case of small samples. However, when the semantic difference between the source domain data and the target domain data is large, transfer learning easily introduces redundant features and leads to negative transfer. According the mechanism of the human brain focusing on effective features while ignoring redundant features in recognition tasks, a brain-like classification method based on adaptive feature matching dual-source domain heterogeneous transfer learning is proposed for the preoperative aided (...)
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  70.  5
    Alpha rhythm of electroencephalography was modulated differently by three transcranial direct current stimulation protocols in patients with ischemic stroke.Yuanyuan Chen, Chunfang Wang, Peiqing Song, Changcheng Sun, Ying Zhang, Xin Zhao & Jingang Du - 2022 - Frontiers in Human Neuroscience 16.
    The heterogeneity of transcranial direct current stimulation protocols and clinical profiles may explain variable results in modulating excitability in the motor cortex after stroke. However, the cortical electrical effects induced by different tDCS protocols remain unclear. Here, we aimed to compare rhythm changes in electroencephalography induced by three tDCS position protocols and the association between tDCS effects and clinical factors in stroke. Nineteen patients with chronic ischemic stroke underwent four experimental sessions with three tDCS protocols [anodal, cathodal, and bilateral ] (...)
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  71.  5
    Maturational trajectory of fusiform gyrus neural activity when viewing faces: From 4 months to 4 years old.Yuhan Chen, Olivia Allison, Heather L. Green, Emily S. Kuschner, Song Liu, Mina Kim, Michelle Slinger, Kylie Mol, Taylor Chiang, Luke Bloy, Timothy P. L. Roberts & J. Christopher Edgar - 2022 - Frontiers in Human Neuroscience 16.
    Infant and young child electrophysiology studies have provided information regarding the maturation of face-encoding neural processes. A limitation of previous research is that very few studies have examined face-encoding processes in children 12–48 months of age, a developmental period characterized by rapid changes in the ability to encode facial information. The present study sought to fill this gap in the literature via a longitudinal study examining the maturation of a primary node in the face-encoding network—the left and right fusiform gyrus. (...)
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  72.  4
    Different Roles of the Left and Right Ventrolateral Prefrontal Cortex in Cognitive Reappraisal: An Online Transcranial Magnetic Stimulation Study.Si Cheng, Xiufu Qiu, Sijin Li, Licheng Mo, Feng Xu & Dandan Zhang - 2022 - Frontiers in Human Neuroscience 16.
    The ventrolateral prefrontal cortex plays a pivotal role in cognitive reappraisal. Previous studies suggested a functional asymmetry of the bilateral VLPFC, but the evidence is still insufficient during cognitive reappraisal. In this study, we conducted an online single-pulse transcranial magnetic stimulation to investigate the causal and distinct roles of the left and right VLPFC in reappraisal. Participants were instructed to reappraise or attend to pictures depicting social exclusion scenarios while the spTMS was applied over the left or right VLPFC of (...)
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  73.  10
    Processing Self-Related Information Under Non-attentional Conditions Revealed by Visual MMN.Sizhe Cheng, Xinhong Li, Qingchen Zhan, Yapei Wang, Yaning Guo, Wei Huang, Yang Cao, Tingwei Feng, Hui Wang, Shengjun Wu, Fei An, Xiuchao Wang, Lun Zhao & Xufeng Liu - 2022 - Frontiers in Human Neuroscience 16.
    Mismatch negativity of event-related potentials is a biomarker reflecting the preattentional change detection under non-attentional conditions. This study was performed to explore whether high self-related information could elicit MMN in the visual channel, indicating the automatic processing of self-related information at the preattentional stage. Thirty-five participants were recruited and asked to list 25 city names including the birthplace. According to the difference of relevance reported from the participants, we divided names of the different cities into high, medium, and low self-related (...)
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  74.  6
    Abnormal Functional Connectivity Between Cerebral Hemispheres in Patients With High Myopia: A Resting FMRI Study Based on Voxel-Mirrored Homotopic Connectivity.Yi Cheng, Xiao-Lin Chen, Ling Shi, Si-Yu Li, Hui Huang, Pei-Pei Zhong & Xiao-Rong Wu - 2022 - Frontiers in Human Neuroscience 16.
    PurposeTo study the changes in functional connections between the left and right hemispheres of patients with high myopia and healthy controls by resting functional magnetic resonance imaging based on voxel-mirrored homotopic connectivity. To study the changes in resting-state functional connectivity between the left and right hemispheres of patients with HM and healthy controls at rest by using resting functional magnetic resonance imaging based on voxel-mirror homotopy connectivity.Patients and MethodsA total of 89 patients with HM and 59 HCs were collected and (...)
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  75.  7
    Design of an Isometric End-Point Force Control Task for Electromyography Normalization and Muscle Synergy Extraction From the Upper Limb Without Maximum Voluntary Contraction.Woorim Cho, Victor R. Barradas, Nicolas Schweighofer & Yasuharu Koike - 2022 - Frontiers in Human Neuroscience 16.
    Muscle synergy analysis via surface electromyography is useful to study muscle coordination in motor learning, clinical diagnosis, and neurorehabilitation. However, current methods to extract muscle synergies in the upper limb suffer from two major issues. First, the necessary normalization of EMG signals is performed via maximum voluntary contraction, which requires maximal isometric force production in each muscle. However, some individuals with motor impairments have difficulties producing maximal effort in the MVC task. In addition, the MVC is known to be highly (...)
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  76.  12
    Evaluating attention deficit hyperactivity disorder symptoms in children and adolescents through tracked head movements in a virtual reality classroom: The effect of social cues with different sensory modalities.Yoon Jae Cho, Jung Yon Yum, Kwanguk Kim, Bokyoung Shin, Hyojung Eom, Yeon-ju Hong, Jiwoong Heo, Jae-jin Kim, Hye Sun Lee & Eunjoo Kim - 2022 - Frontiers in Human Neuroscience 16.
    BackgroundAttention deficit hyperactivity disorder is clinically diagnosed; however, quantitative analysis to statistically analyze the symptom severity of children with ADHD via the measurement of head movement is still in progress. Studies focusing on the cues that may influence the attention of children with ADHD in classroom settings, where children spend a considerable amount of time, are relatively scarce. Virtual reality allows real-life simulation of classroom environments and thus provides an opportunity to test a range of theories in a naturalistic and (...)
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  77.  4
    How to Decide the Number of Gait Cycles in Different Low-Pass Filters to Extract Motor Modules by Non-negative Matrix Factorization During Walking in Chronic Post-stroke Patients.Yuta Chujo, Kimihiko Mori, Tomoki Kitawaki, Masanori Wakida, Tomoyuki Noda & Kimitaka Hase - 2022 - Frontiers in Human Neuroscience 16.
    The motor modules during human walking are identified using non-negative matrix factorization from surface electromyography signals. The extraction of motor modules in healthy participants is affected by the change in pre-processing of EMG signals, such as low-pass filters ; however, the effect of different pre-processing methods, such as the number of necessary gait cycles in post-stroke patients with varying steps, remains unknown. We aimed to specify that the number of GCs influenced the motor modules extracted in the consideration of LPFs (...)
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  78.  3
    Association of prenatal modifiable risk factors with attention-deficit hyperactivity disorder outcomes at age 10 and 15 in an extremely low gestational age cohort. [REVIEW]David M. Cochran, Elizabeth T. Jensen, Jean A. Frazier, Isha Jalnapurkar, Sohye Kim, Kyle R. Roell, Robert M. Joseph, Stephen R. Hooper, Hudson P. Santos, Karl C. K. Kuban, Rebecca C. Fry & T. Michael O’Shea - 2022 - Frontiers in Human Neuroscience 16:911098.
    BackgroundThe increased risk of developing attention-deficit hyperactivity disorder (ADHD) in extremely preterm infants is well-documented. Better understanding of perinatal risk factors, particularly those that are modifiable, can inform prevention efforts.MethodsWe examined data from the Extremely Low Gestational Age Newborns (ELGAN) Study. Participants were screened for ADHD at age 10 with the Child Symptom Inventory-4 (N = 734) and assessed at age 15 with a structured diagnostic interview (MINI-KID) to evaluate for the diagnosis of ADHD (N = 575). We studied associations (...)
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  79.  1
    Editorial: Still Searching for the Origin of Migraine: From Comorbidities to Chronicization.Gianluca Coppola, Roberta Messina, Linxin Li & Claudia Altamura - 2022 - Frontiers in Human Neuroscience 16.
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  80.  3
    Pediatric Responses to Fundamental and Formant Frequency Altered Auditory Feedback: A Scoping Review.Caitlin Coughler, Keelia L. Quinn de Launay, David W. Purcell, Janis Oram Cardy & Deryk S. Beal - 2022 - Frontiers in Human Neuroscience 16.
    PurposeThe ability to hear ourselves speak has been shown to play an important role in the development and maintenance of fluent and coherent speech. Despite this, little is known about the developing speech motor control system throughout childhood, in particular if and how vocal and articulatory control may differ throughout development. A scoping review was undertaken to identify and describe the full range of studies investigating responses to frequency altered auditory feedback in pediatric populations and their contributions to our understanding (...)
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  81.  3
    A Neuropsychological Rehabilitation Framework to Address Cognitive and Neurobehavioral Impairments After Strokes to the Anterior Communicating Artery.Ramiro Cruces, Indhira Muñoz-García, Santiago J. Palmer-Cancel & Christian Salas - 2022 - Frontiers in Human Neuroscience 16.
    Patients with strokes to the Anterior Communicating Artery pose an important challenge to rehabilitation teams due to a particular mix of cognitive and behavioral impairments. These deficits often compromise engagement with rehabilitation, learning and generalization. The goal of this article is to describe the long-term presentation of a patient with an ACoA stroke as well as her rehabilitation needs and the many challenges experienced by the rehabilitation team when attempting to facilitate functional, vocational and psychosocial recovery. Based on this case, (...)
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  82.  3
    Editorial: When the Body Feels Like Mine: Constructing and Deconstructing the Sense of Body Ownership Through the Lifespan.Laura Crucianelli, Carissa J. Cascio, Roy Salomon & Gerardo Salvato - 2022 - Frontiers in Human Neuroscience 16.
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  83.  4
    The associations between specific-type sedentary behaviors and cognitive flexibility in adolescents.Jie Cui, Lin Li & Chao Dong - 2022 - Frontiers in Human Neuroscience 16.
    Background: The prevalence of sedentary behavior in adolescents has aroused social attention. The association between sedentary behavior and cognitive flexibility remains unclear, and it may vary depending on the type of sedentary behavior. This study aimed to investigate the associations between specific-type sedentary behaviors and cognitive flexibility in adolescents.Method: A total of 700 Chinese adolescents aged 10–15 years were recruited. The self-report questionnaire was used to assess total sedentary time, recreational screen-based sedentary time, and educational sedentary time. The More-odd shifting (...)
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  84.  1
    Single Blind Randomized Controlled Trial of Modified Constraint-Induced Movement Therapy in Infants With the Sequelas of Unilateral Brachial Plexus Injury.Zhenzhen Cui, Xi le LiuChen, Haiyan Zeng, Shizhu Zheng & De Wu - 2022 - Frontiers in Human Neuroscience 16:900214.
    ObjectiveTo explore the effect of modified constraint-induced movement therapy on upper limbs residual dysfunction for infancy with the sequelas of unilateral brachial plexus injury.MethodsSingle blind randomized controlled trial of mCIMT vs. standard care. An enrolling 31 infants with a uBPI exhibiting residual dysfunction of the affected upper limb for over 6 months was conducted. And functional outcomes pertaining to the affected upper limb were assessed via AMS, GRES, RHS, and MSS at 0, 3, and 6 months after treatment.ResultsNo differences were (...)
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  85.  3
    Neuroplasticity in Motor Learning Under Variable and Constant Practice Conditions—Protocol of Randomized Controlled Trial.Stanisław H. Czyż, Jarosław Marusiak, Patrícia Klobušiaková, Zuzana Sajdlová & Irena Rektorová - 2022 - Frontiers in Human Neuroscience 16.
    BackgroundThere is numerous literature on mechanisms underlying variability of practice advantages. Literature includes both behavioral and neuroimaging studies. Unfortunately, no studies are focusing on practice in constant conditions to the best of our knowledge. Hence it is essential to assess possible differences in mechanisms of neuroplasticity between constant vs. variable practice conditions. The primary objectives of the study described in this protocol will be: to determine the brain’s structural and functional changes following constant and variable practice conditions in motor learning (...)
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  86.  2
    Editorial: Predictive mechanisms in action, perception, cognition, and clinical disorders.Anila M. D'Mello, Patric Bach, Philip R. Corlett & Liron Rozenkrantz - 2022 - Frontiers in Human Neuroscience 16.
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  87.  5
    Structural Features Predict Sexual Trauma and Interpersonal Problems in Borderline Personality Disorder but Not in Controls: A Multi-Voxel Pattern Analysis.Harold Dadomo, Gerardo Salvato, Gaia Lapomarda, Zafer Ciftci, Irene Messina & Alessandro Grecucci - 2022 - Frontiers in Human Neuroscience 16.
    Child trauma plays an important role in the etiology of Bordeline Personality Disorder. Of all traumas, sexual trauma is the most common, severe and most associated with receiving a BPD diagnosis when adult. Etiologic models posit sexual abuse as a prognostic factor in BPD. Here we apply machine learning using Multiple Kernel Regression to the Magnetic Resonance Structural Images of 20 BPD and 13 healthy control to see whether their brain predicts five sources of traumas: sex abuse, emotion neglect, emotional (...)
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  88.  3
    Chronic Pain in the Elderly: Mechanisms and Perspectives.Ana P. A. Dagnino & Maria M. Campos - 2022 - Frontiers in Human Neuroscience 16:736688.
    Chronic pain affects a large part of the population causing functional disability, being often associated with coexisting psychological disorders, such as depression and anxiety, besides cognitive deficits, and sleep disturbance. The world elderly population has been growing over the last decades and the negative consequences of chronic pain for these individuals represent a current clinical challenge. The main painful complaints in the elderly are related to neurodegenerative and musculoskeletal conditions, peripheral vascular diseases, arthritis, and osteoarthritis, contributing toward poorly life quality, (...)
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  89.  5
    Examining the Effect of Transcranial Electrical Stimulation and Cognitive Training on Processing Speed in Pediatric Attention Deficit Hyperactivity Disorder: A Pilot Study.Ornella Dakwar-Kawar, Itai Berger, Snir Barzilay, Ephraim S. Grossman, Roi Cohen Kadosh & Mor Nahum - 2022 - Frontiers in Human Neuroscience 16.
    ObjectiveProcessing Speed, the ability to perceive and react fast to stimuli in the environment, has been shown to be impaired in children with attention deficit hyperactivity disorder. However, it is unclear whether PS can be improved following targeted treatments for ADHD. Here we examined potential changes in PS following application of transcranial electric stimulation combined with cognitive training in children with ADHD. Specifically, we examined changes in PS in the presence of different conditions of mental fatigue.MethodsWe used a randomized double-blind (...)
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  90.  4
    PELP: Accounting for Missing Data in Neural Time Series by Periodic Estimation of Lost Packets.Evan M. Dastin-van Rijn, Nicole R. Provenza, Gregory S. Vogt, Michelle Avendano-Ortega, Sameer A. Sheth, Wayne K. Goodman, Matthew T. Harrison & David A. Borton - 2022 - Frontiers in Human Neuroscience 16.
    Recent advances in wireless data transmission technology have the potential to revolutionize clinical neuroscience. Today sensing-capable electrical stimulators, known as “bidirectional devices”, are used to acquire chronic brain activity from humans in natural environments. However, with wireless transmission come potential failures in data transmission, and not all available devices correctly account for missing data or provide precise timing for when data losses occur. Our inability to precisely reconstruct time-domain neural signals makes it difficult to apply subsequent neural signal processing techniques (...)
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  91.  6
    Pre-stimulus Alpha Activity Modulates Face and Object Processing in the Intra-Parietal Sulcus, a MEG Study.Narjes Soltani Dehaghani, Burkhard Maess, Reza Khosrowabadi, Reza Lashgari, Sven Braeutigam & Mojtaba Zarei - 2022 - Frontiers in Human Neuroscience 16.
    Face perception is crucial in all social animals. Recent studies have shown that pre-stimulus oscillations of brain activity modulate the perceptual performance of face vs. non-face stimuli, specifically under challenging conditions. However, it is unclear if this effect also occurs during simple tasks, and if so in which brain regions. Here we used magnetoencephalography and a 1-back task in which participants decided if the two sequentially presented stimuli were the same or not in each trial. The aim of the study (...)
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  92.  4
    No evidence for an effect of selective spatial attention on the development of secondary hyperalgesia: A replication study.Delia Della Porta, Marie-Lynn Vilz, Avgustina Kuzminova, Lieve Filbrich, André Mouraux & Valéry Legrain - 2022 - Frontiers in Human Neuroscience 16:997230.
    Central sensitization refers to the increased responsiveness of nociceptive neurons in the central nervous system after repeated or sustained peripheral nociceptor activation. It is hypothesized to play a key role in the development of chronic pain. A hallmark of central sensitization is an increased sensitivity to noxious mechanical stimuli extending beyond the injured location, known as secondary hyperalgesia. For its ability to modulate the transmission and the processing of nociceptive inputs, attention could constitute a promising target to prevent central sensitization (...)
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  93.  9
    Mental and physical training with meditation and aerobic exercise improved mental health and well-being in teachers during the COVID-19 pandemic.Docia L. Demmin, Steven M. Silverstein & Tracey J. Shors - 2022 - Frontiers in Human Neuroscience 16.
    Teachers face significant stressors in relation to their work, placing them at increased risk for burnout and attrition. The COVID-19 pandemic has brought about additional challenges, resulting in an even greater burden. Thus, strategies for reducing stress that can be delivered virtually are likely to benefit this population. Mental and Physical Training combines meditation with aerobic exercise and has resulted in positive mental and physical health outcomes in both clinical and subclinical populations. The aim of this pilot study was to (...)
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  94.  2
    EEG-Based Index for Timely Detecting User’s Drowsiness Occurrence in Automotive Applications.Gianluca Di Flumeri, Vincenzo Ronca, Andrea Giorgi, Alessia Vozzi, Pietro Aricò, Nicolina Sciaraffa, Hong Zeng, Guojun Dai, Wanzeng Kong, Fabio Babiloni & Gianluca Borghini - 2022 - Frontiers in Human Neuroscience 16.
    Human errors are widely considered among the major causes of road accidents. Furthermore, it is estimated that more than 90% of vehicle crashes causing fatal and permanent injuries are directly related to mental tiredness, fatigue, and drowsiness of the drivers. In particular, driving drowsiness is recognized as a crucial aspect in the context of road safety, since drowsy drivers can suddenly lose control of the car. Moreover, the driving drowsiness episodes mostly appear suddenly without any prior behavioral evidence. The present (...)
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  95.  3
    A data-driven machine learning approach for brain-computer interfaces targeting lower limb neuroprosthetics.Arnau Dillen, Elke Lathouwers, Aleksandar Miladinović, Uros Marusic, Fakhreddine Ghaffari, Olivier Romain, Romain Meeusen & Kevin De Pauw - 2022 - Frontiers in Human Neuroscience 16.
    Prosthetic devices that replace a lost limb have become increasingly performant in recent years. Recent advances in both software and hardware allow for the decoding of electroencephalogram signals to improve the control of active prostheses with brain-computer interfaces. Most BCI research is focused on the upper body. Although BCI research for the lower extremities has increased in recent years, there are still gaps in our knowledge of the neural patterns associated with lower limb movement. Therefore, the main objective of this (...)
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  96.  6
    A data-driven machine learning approach for brain-computer interfaces targeting lower limb neuroprosthetics.Arnau Dillen, Elke Lathouwers, Aleksandar Miladinović, Uros Marusic, Fakhredinne Ghaffari, Olivier Romain, Romain Meeusen & Kevin De Pauw - 2022 - Frontiers in Human Neuroscience 16.
    Prosthetic devices that replace a lost limb have become increasingly performant in recent years. Recent advances in both software and hardware allow for the decoding of electroencephalogram signals to improve the control of active prostheses with brain-computer interfaces. Most BCI research is focused on the upper body. Although BCI research for the lower extremities has increased in recent years, there are still gaps in our knowledge of the neural patterns associated with lower limb movement. Therefore, the main objective of this (...)
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  97.  4
    Editorial: Advanced Neuroimaging Methods in Brain Disorders.Jurong Ding, Wei Liao & Dajiang Zhu - 2022 - Frontiers in Human Neuroscience 16.
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  98.  6
    Enhancing Brain Connectivity With Infra-Low Frequency Neurofeedback During Aging: A Pilot Study.Olga R. Dobrushina, Larisa A. Dobrynina, Galina A. Arina, Elena I. Kremneva, Evgenia S. Novikova, Mariia V. Gubanova, Ekaterina V. Pechenkova, Anastasia D. Suslina, Vlada V. Aristova, Viktoriya V. Trubitsyna & Marina V. Krotenkova - 2022 - Frontiers in Human Neuroscience 16.
    Aging is associated with decreased functional connectivity in the main brain networks, which can underlie changes in cognitive and emotional processing. Neurofeedback is a promising non-pharmacological approach for the enhancement of brain connectivity. Previously, we showed that a single session of infra-low frequency neurofeedback results in increased connectivity between sensory processing networks in healthy young adults. In the current pilot study, we aimed to evaluate the possibility of enhancing brain connectivity during aging with the use of infra-low frequency neurofeedback. Nine (...)
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  99.  4
    Editorial: Rhythmic Patterns in Neuroscience and Human Physiology.Nadia Dominici, Marco Iosa, Giuseppe Vannozzi & Daniela De Bartolo - 2022 - Frontiers in Human Neuroscience 16.
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  100.  5
    The Effect of Repetitive Transcranial Magnetic Stimulation of Cerebellar Swallowing Cortex on Brain Neural Activities: A Resting-State fMRI Study.Linghui Dong, Wenshuai Ma, Qiang Wang, Xiaona Pan, Yuyang Wang, Chao Han & Pingping Meng - 2022 - Frontiers in Human Neuroscience 16.
    ObjectiveThe effects and possible mechanisms of cerebellar high-frequency repetitive transcranial magnetic stimulation on swallowing-related neural networks were studied using resting-state functional magnetic resonance imaging.MethodA total of 23 healthy volunteers were recruited, and 19 healthy volunteers were finally included for the statistical analysis. Before stimulation, the cerebellar hemisphere dominant for swallowing was determined by the single-pulse TMS. The cerebellar representation of the suprahyoid muscles of this hemisphere was selected as the target for stimulation with 10 Hz rTMS, 100% resting motor threshold, (...)
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  101.  6
    The relationship between physical activity and trait anxiety in college students: The mediating role of executive function.Zhiwei Dong, Peng Wang, Xin Xin, Shufan Li, Jing Wang, Jinlei Zhao & Xing Wang - 2022 - Frontiers in Human Neuroscience 16:1009540.
    ObjectivesAimed to analyze the mediating effect of executive function between physical activity level and trait anxiety in college students.MethodsThe International Physical Activity Questionnaire, State-Trait Anxiety Inventory, Stroop task, 1-back task, and More-odd shifting task were used to analyze 248 college students.ResultsTrait anxiety were significantly correlated with shifting function (r = 0.182, P = 0.004) and inhibition function (r = 0.163, P = 0.010) and not with working memory (r = 0.056, P = 0.385). Vigorous physical activity (VPA) was most highly (...)
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  102.  4
    Obesity, Psychological Distress, and Resting State Connectivity of the Hippocampus and Amygdala Among Women With Early-Stage Breast Cancer.Shannon D. Donofry, Alina Lesnovskaya, Jermon A. Drake, Hayley S. Ripperger, Alysha D. Gilmore, Patrick T. Donahue, Mary E. Crisafio, George Grove, Amanda L. Gentry, Susan M. Sereika, Catherine M. Bender & Kirk I. Erickson - 2022 - Frontiers in Human Neuroscience 16.
    ObjectiveOverweight and obesity [body mass index ≥ 25 kg/m2] are associated with poorer prognosis among women with breast cancer, and weight gain is common during treatment. Symptoms of depression and anxiety are also highly prevalent in women with breast cancer and may be exacerbated by post-diagnosis weight gain. Altered brain function may underlie psychological distress. Thus, this secondary analysis examined the relationship between BMI, psychological health, and resting state functional connectivity among women with breast cancer.MethodsThe sample included 34 post-menopausal women (...)
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  103.  4
    Upward Shifts in the Internal Representation of Frequency Can Persist Over a 3-Year Period for Cochlear Implant Patients Fit With a Relatively Short Electrode Array.Michael F. Dorman, Sarah C. Natale, Jack H. Noble & Daniel M. Zeitler - 2022 - Frontiers in Human Neuroscience 16.
    Patients fit with cochlear implants commonly indicate at the time of device fitting and for some time after, that the speech signal sounds abnormal. A high pitch or timbre is one component of the abnormal percept. In this project, our aim was to determine whether a number of years of CI use reduced perceived upshifts in frequency spectrum and/or voice fundamental frequency. The participants were five individuals who were deaf in one ear and who had normal hearing in the other (...)
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  104.  7
    The Role of Brain-Derived Neurotrophic Factor Signaling in Central Nervous System Disease Pathogenesis.Shu-Hui Dou, Yu Cui, Shu-Ming Huang & Bo Zhang - 2022 - Frontiers in Human Neuroscience 16.
    Recent studies have found abnormal levels of brain-derived neurotrophic factor in a variety of central nervous system diseases. This suggests that BDNF may be involved in the pathogenesis of these diseases. Moreover, regulating BDNF signaling may represent a potential treatment for such diseases. With reference to recent research papers in related fields, this article reviews the production and regulation of BDNF in CNS and the role of BDNF signaling disorders in these diseases. A brief introduction of the clinical application status (...)
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  105.  2
    The Influence of the Modulation Index on Frequency-Modulated Steady-State Visual Evoked Potentials.Alexander M. Dreyer, Benjamin L. A. Heikkinen & Christoph S. Herrmann - 2022 - Frontiers in Human Neuroscience 16.
    Based on increased user experience during stimulation, frequency-modulated steady-state visual evoked potentials have been suggested as an improved stimulation method for brain-computer interfaces. Adapting such a novel stimulation paradigm requires in-depth analyses of all different stimulation parameters and their influence on brain responses as well as the user experience during the stimulation. In the current manuscript, we assess the influence of different values for the modulation index, which determine the spectral distribution in the stimulation signal on FM-SSVEPs. We visually stimulated (...)
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  106.  9
    The Neural Mechanism of Long-Term Motor Training Affecting Athletes’ Decision-Making Function: An Activation Likelihood Estimation Meta-Analysis.Ying Du, Lingxiao He, Yiyan Wang & Dengbin Liao - 2022 - Frontiers in Human Neuroscience 16.
    Decision-making is an advanced cognitive function that promotes information processes in complex motor situations. In recent years, many neuroimaging studies have assessed the effects of long-term motor training on athletes’ brain activity while performing decision-making tasks, but the findings have been inconsistent and a large amount of data has not been quantitatively summarized until now. Therefore, this study aimed to identify the neural mechanism of long-term motor training affecting the decision-making function of athletes by using activation likelihood estimation meta-analysis. Altogether, (...)
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  107.  3
    Exploring the effects of head movements and accompanying gaze fixation switch on steady-state visual evoked potential.Junyi Duan, Songwei Li, Li Ling, Ning Zhang & Jianjun Meng - 2022 - Frontiers in Human Neuroscience 16:943070.
    In a realistic steady-state visual evoked potential (SSVEP) based brain-computer interface (BCI) application like driving a car or controlling a quadrotor, observing the surrounding environment while simultaneously gazing at the stimulus is necessary. This kind of application inevitably could cause head movements and variation of the accompanying gaze fixation point, which might affect the SSVEP and BCI’s performance. However, few papers studied the effects of head movements and gaze fixation switch on SSVEP response, and the corresponding BCI performance. This study (...)
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  108.  4
    The No-Report Paradigm: A Revolution in Consciousness Research?Irem Duman, Isabell Sophia Ehmann, Alicia Ronnie Gonsalves, Zeynep Gültekin, Jonathan Van den Berckt & Cees van Leeuwen - 2022 - Frontiers in Human Neuroscience 16:861517.
    In the cognitive neuroscience of consciousness, participants have commonly been instructed to report their conscious content. This, it was claimed, risks confounding the neural correlates of consciousness (NCC) with their preconditions, i.e., allocation of attention, and consequences, i.e., metacognitive reflection. Recently, the field has therefore been shifting towards no-report paradigms. No-report paradigms draw their validity from a direct comparison with no-report conditions. We analyze several examples of such comparisons and identify alternative interpretations of their results and/or methodological issues in all (...)
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  109.  3
    Neuroprotection in late life attention-deficit/hyperactivity disorder: A review of pharmacotherapy and phenotype across the lifespan. [REVIEW]Cintya Nirvana Dutta, Leonardo Christov-Moore, Hernando Ombao & Pamela K. Douglas - 2022 - Frontiers in Human Neuroscience 16:938501.
    For decades, psychostimulants have been the gold standard pharmaceutical treatment for attention-deficit/hyperactivity disorder (ADHD). In the United States, an astounding 9% of all boys and 4% of girls will be prescribed stimulant drugs at some point during their childhood. Recent meta-analyses have revealed that individuals with ADHD have reduced brain volume loss later in life (>60 y.o.) compared to the normal aging brain, which suggests that either ADHD or its treatment may be neuroprotective. Crucially, these neuroprotective effects were significant in (...)
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  110.  4
    No Evidence for a Boost in Psychosocial Functioning in Older Age After a 6-Months Physical Exercise Intervention.Sandra Düzel, Johanna Drewelies, Sarah E. Polk, Carola Misgeld, Johanna Porst, Bernd Wolfarth, Simone Kühn, Andreas M. Brandmaier & Elisabeth Wenger - 2022 - Frontiers in Human Neuroscience 16.
    The beneficial effects of physical exercise on physical health and cognitive functioning have been repeatedly shown. However, evidence of its effect on psychosocial functioning in healthy adults is still scarce or inconclusive. One limitation of many studies examining this link is their reliance on correlational approaches or specific subpopulations, such as clinical populations. The present study investigated the effects of a physical exercise intervention on key factors of psychosocial functioning, specifically well-being, stress, loneliness, and future time perspective. We used data (...)
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  111.  1
    A Multidimensional Investigation of Sensory Processing in Autism: Parent- and Self-Report Questionnaires, Psychophysical Thresholds, and Event-Related Potentials in the Auditory and Somatosensory Modalities.Patrick Dwyer, Yukari Takarae, Iman Zadeh, Susan M. Rivera & Clifford D. Saron - 2022 - Frontiers in Human Neuroscience 16.
    BackgroundReconciling results obtained using different types of sensory measures is a challenge for autism sensory research. The present study used questionnaire, psychophysical, and neurophysiological measures to characterize autistic sensory processing in different measurement modalities.MethodsParticipants were 46 autistic and 21 typically developing 11- to 14-year-olds. Participants and their caregivers completed questionnaires regarding sensory experiences and behaviors. Auditory and somatosensory event-related potentials were recorded as part of a multisensory ERP task. Auditory detection, tactile static detection, and tactile spatial resolution psychophysical thresholds were (...)
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  112.  6
    Neurostimulation artifact removal for implantable sensors improves signal clarity and decoding of motor volition.Eric J. Earley, Anton Berneving, Jan Zbinden & Max Ortiz-Catalan - 2022 - Frontiers in Human Neuroscience 16:1030207.
    As the demand for prosthetic limbs with reliable and multi-functional control increases, recent advances in myoelectric pattern recognition and implanted sensors have proven considerably advantageous. Additionally, sensory feedback from the prosthesis can be achieved via stimulation of the residual nerves, enabling closed-loop control over the prosthesis. However, this stimulation can cause interfering artifacts in the electromyographic (EMG) signals which deteriorate the reliability and function of the prosthesis. Here, we implement two real-time stimulation artifact removal algorithms, Template Subtraction (TS) and ε-Normalized (...)
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  113.  3
    Low test–retest reliability of a protocol for assessing somatosensory cortex excitability generated from sensory nerves of the lower back.Katja Ehrenbrusthoff, Cormac G. Ryan, Denis J. Martin, Volker Milnik, Hubert R. Dinse & Christian Grüneberg - 2022 - Frontiers in Human Neuroscience 16.
    In people with chronic low back pain, maladaptive structural and functional changes on a cortical level have been identified. On a functional level, somatosensory cortical excitability has been shown to be reduced in chronic pain conditions, resulting in cortical disinhibition. The occurrence of structural and/or functional maladaptive cortical changes in people with CLBP could play a role in maintaining the pain. There is currently no measurement protocol for cortical excitability that employs stimulation directly to the lower back. We developed a (...)
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  114.  3
    Neural Synchrony During Naturalistic Information Processing Is Associated With Aerobically Active Lifestyle and Cardiorespiratory Fitness in Cognitively Intact Older Adults.Tamir Eisenstein, Nir Giladi, Talma Hendler, Ofer Havakuk & Yulia Lerner - 2022 - Frontiers in Human Neuroscience 16.
    The functional neural mechanisms underlying the cognitive benefits of aerobic exercise have been a subject of ongoing research in recent years. However, while most neuroimaging studies to date which examined functional neural correlates of aerobic exercise have used simple stimuli in highly controlled and artificial experimental conditions, our everyday life experiences require a much more complex and dynamic neurocognitive processing. Therefore, we have used a naturalistic complex information processing fMRI paradigm of story comprehension to investigate the role of an aerobically (...)
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  115.  4
    A New Functional Magnetic Resonance Imaging Localizer for Preoperative Language Mapping Using a Sentence Completion Task: Validity, Choice of Baseline Condition, and Test–Retest Reliability.Kirill Elin, Svetlana Malyutina, Oleg Bronov, Ekaterina Stupina, Aleksei Marinets, Anna Zhuravleva & Olga Dragoy - 2022 - Frontiers in Human Neuroscience 16.
    To avoid post-neurosurgical language deficits, intraoperative mapping of the language function in the brain can be complemented with preoperative mapping with functional magnetic resonance imaging. The validity of an fMRI “language localizer” paradigm crucially depends on the choice of an optimal language task and baseline condition. This study presents a new fMRI “language localizer” in Russian using overt sentence completion, a task that comprehensively engages the language function by involving both production and comprehension at the word and sentence level. The (...)
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  116.  4
    An Action-Independent Role for Midfrontal Theta Activity Prior to Error Commission.João Estiveira, Camila Dias, Diana Costa, João Castelhano, Miguel Castelo-Branco & Teresa Sousa - 2022 - Frontiers in Human Neuroscience 16.
    Error-related electroencephalographic signals have been widely studied concerning the human cognitive capability of differentiating between erroneous and correct actions. Midfrontal error-related negativity and theta band oscillations are believed to underlie post-action error monitoring. However, it remains elusive how early monitoring activity is trackable and what are the pre-response brain mechanisms related to performance monitoring. Moreover, it is still unclear how task-specific parameters, such as cognitive demand or motor control, influence these processes. Here, we aimed to test pre- and post-error EEG (...)
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  117.  6
    Automated Multiclass Artifact Detection in Diffusion MRI Volumes via 3D Residual Squeeze-and-Excitation Convolutional Neural Networks.Nabil Ettehadi, Pratik Kashyap, Xuzhe Zhang, Yun Wang, David Semanek, Karan Desai, Jia Guo, Jonathan Posner & Andrew F. Laine - 2022 - Frontiers in Human Neuroscience 16.
    Diffusion MRI is widely used to investigate neuronal and structural development of brain. dMRI data is often contaminated with various types of artifacts. Hence, artifact type identification in dMRI volumes is an essential pre-processing step prior to carrying out any further analysis. Manual artifact identification amongst a large pool of dMRI data is a highly labor-intensive task. Previous attempts at automating this process are often limited to a binary classification of the dMRI volumes or focus on detecting a single type (...)
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  118.  9
    A Wearable Mixed Reality Platform to Augment Overground Walking: A Feasibility Study.Emily Evans, Megan Dass, William M. Muter, Christopher Tuthill, Andrew Q. Tan & Randy D. Trumbower - 2022 - Frontiers in Human Neuroscience 16.
    Humans routinely modify their walking speed to adapt to functional goals and physical demands. However, damage to the central nervous system often results in abnormal modulation of walking speed and increased risk of falls. There is considerable interest in treatment modalities that can provide safe and salient training opportunities, feedback about walking performance, and that may augment less reliable sensory feedback within the CNS after injury or disease. Fully immersive virtual reality technologies show benefits in boosting training-related gains in walking (...)
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  119.  3
    Walking and Balance Outcomes Are Improved Following Brief Intensive Locomotor Skill Training but Are Not Augmented by Transcranial Direct Current Stimulation in Persons With Chronic Spinal Cord Injury.Nicholas H. Evans, Cazmon Suri & Edelle C. Field-Fote - 2022 - Frontiers in Human Neuroscience 16.
    Motor training to improve walking and balance function is a common aspect of rehabilitation following motor-incomplete spinal cord injury. Evidence suggests that moderate- to high-intensity exercise facilitates neuroplastic mechanisms that support motor skill acquisition and learning. Furthermore, enhancing corticospinal drive via transcranial direct current stimulation may augment the effects of motor training. In this pilot study, we investigated whether a brief moderate-intensity locomotor-related motor skill training circuit, with and without tDCS, improved walking and balance outcomes in persons with MISCI. In (...)
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  120.  3
    Influence of Controlled Stomatognathic Motor Activity on Sway, Control and Stability of the Center of Mass During Dynamic Steady-State Balance—An Uncontrolled Manifold Analysis.Cagla Fadillioglu, Lisa Kanus, Felix Möhler, Steffen Ringhof, Daniel Hellmann & Thorsten Stein - 2022 - Frontiers in Human Neuroscience 16:868828.
    Multiple sensory signals from visual, somatosensory and vestibular systems are used for human postural control. To maintain postural stability, the central nervous system keeps the center of mass (CoM) within the base of support. The influence of the stomatognathic motor system on postural control has been established under static conditions, but it has not yet been investigated during dynamic steady-state balance. The purpose of the study was to investigate the effects of controlled stomatognathic motor activity on the control and stability (...)
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  121.  9
    Memory Modulation Via Non-invasive Brain Stimulation: Status, Perspectives, and Ethical Issues.Mirko Farina & Andrea Lavazza - 2022 - Frontiers in Human Neuroscience 16.
    While research to improve memory or counter decay caused by neurodegenerative diseases has a fairly long history, scientific attempts to erase memories are very recent. The use of non-invasive brain stimulation for memory modulation represents a new and promising application for the treatment of certain disorders [such as Post-Traumatic Stress Disorder ]. However, numerous ethical issues are related to memory intervention. In particular, the possibility of using forms of non-invasive brain stimulation requires to distinguish treatment interventions from the enhancement of (...)
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  122.  3
    Influence of sagittal pelvic attitude on gait pattern in normally developed people and interactions with neurological pathologies: A pilot study.Martina Favetta, Alberto Romano, Susanna Summa, Alessandra Colazza, Silvia Minosse, Gessica Vasco, Enrico Castelli & Maurizio Petrarca - 2022 - Frontiers in Human Neuroscience 16.
    BackgroundGait Analysis of healthy people, imitating pathological conditions while walking, has increased our understanding of biomechanical factors. The influence of the pelvis as a biomechanical constraint during gait is not specifically studied. How could mimicking a pelvic attitude influence the dynamic mechanical interaction of the body segments? We proposed an investigation of the pelvic attitude role on the gait pattern of typically developed people when they mimicked pelvic anteversion and posteroversion.Materials and methodsSeventeen healthy volunteers were enrolled in this study. They (...)
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  123.  2
    Responsive Thalamic Neurostimulation: A Systematic Review of a Promising Approach for Refractory Epilepsy.Chaim M. Feigen & Emad N. Eskandar - 2022 - Frontiers in Human Neuroscience 16.
    IntroductionResponsive neurostimulation is an evolving therapeutic option for patients with treatment-refractory epilepsy. Open-loop, continuous stimulation of the anterior thalamic nuclei is the only approved modality, yet chronic stimulation rarely induces complete seizure remission and is associated with neuropsychiatric adverse effects. Accounts of off-label responsive stimulation in thalamic nuclei describe significant improvements in patients who have failed multiple drug regimens, vagal nerve stimulation, and other invasive measures. This systematic review surveys the currently available data supporting the use of responsive thalamic neurostimulation (...)
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  124.  3
    Sport Practice, Fluid Reasoning, and Soft Skills in 10- to 18-Year-Olds.Tommaso Feraco & Chiara Meneghetti - 2022 - Frontiers in Human Neuroscience 16.
    Engaging in physical activity and sports has been associated with various cognitive abilities and other personal characteristics. The contemporary link between doing sports and personal attributes such as soft skills and an individual’s cognitive abilities have yet to be investigated, however. This study aims to analyze the association between years of practicing a sport, cognitive abilities, and personal attributes. A large sample of 1,115 individuals completed the Cattell test and answered a questionnaire measuring six soft skills. A multivariate regression analysis (...)
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  125.  2
    Post-error Slowing Reflects the Joint Impact of Adaptive and Maladaptive Processes During Decision Making.Fanny Fievez, Gerard Derosiere, Frederick Verbruggen & Julie Duque - 2022 - Frontiers in Human Neuroscience 16:864590.
    Errors and their consequences are typically studied by investigating changes in decision speed and accuracy in trials that follow an error, commonly referred to as “post-error adjustments”. Many studies have reported that subjects slow down following an error, a phenomenon called “post-error slowing” (PES). However, the functional significance of PES is still a matter of debate as it is not always adaptive. That is, it is not always associated with a gain in performance and can even occur with a decline (...)
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  126.  1
    Cerebral hemodynamic changes to transcranial Doppler sonography in celiac disease: A pilot study.Francesco Fisicaro, Giuseppe Lanza, Carmela Cinzia D’Agate, Manuela Pennisi, Mariagiovanna Cantone, Giovanni Pennisi, Marios Hadjivassiliou & Rita Bella - 2022 - Frontiers in Human Neuroscience 16:931727.
    BackgroundSonographic mesenteric pattern in celiac disease (CD) suggests a hyperdynamic circulation. Despite the well-known CD-related neurological involvement, no study has systematically explored the cerebral hemodynamics to transcranial Doppler sonography.Materials and methodsMontreal Cognitive Assessment (MoCA) and 17-item Hamilton Depression Rating Scale (HDRS) were assessed in 15 newly diagnosed subjects with CD and 15 age-, sex-, and education-matched healthy controls. Cerebral blood flow (CBF) velocities and indices of resistivity (RI) and pulsatility (PI) from the middle cerebral artery (MCA), bilaterally, and the basilar (...)
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  127.  2
    Mothers’ Attachment Representations and Children’s Brain Structure.Megan H. Fitter, Jessica A. Stern, Martha D. Straske, Tamara Allard, Jude Cassidy & Tracy Riggins - 2022 - Frontiers in Human Neuroscience 16.
    Ample research demonstrates that parents’ experience-based mental representations of attachment—cognitive models of close relationships—relate to their children’s social-emotional development. However, no research to date has examined how parents’ attachment representations relate to another crucial domain of children’s development: brain development. The present study is the first to integrate the separate literatures on attachment and developmental social cognitive neuroscience to examine the link between mothers’ attachment representations and 3- to 8-year-old children’s brain structure. We hypothesized that mothers’ attachment representations would relate (...)
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  128.  4
    A pediatric near-infrared spectroscopy brain-computer interface based on the detection of emotional valence.Erica D. Floreani, Silvia Orlandi & Tom Chau - 2022 - Frontiers in Human Neuroscience 16:938708.
    Brain-computer interfaces (BCIs) are being investigated as an access pathway to communication for individuals with physical disabilities, as the technology obviates the need for voluntary motor control. However, to date, minimal research has investigated the use of BCIs for children. Traditional BCI communication paradigms may be suboptimal given that children with physical disabilities may face delays in cognitive development and acquisition of literacy skills. Instead, in this study we explored emotional state as an alternative access pathway to communication. We developed (...)
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  129.  4
    On the feasibility of simple brain-computer interface systems for enabling children with severe physical disabilities to explore independent movement.Erica D. Floreani, Danette Rowley, Dion Kelly, Eli Kinney-Lang & Adam Kirton - 2022 - Frontiers in Human Neuroscience 16:1007199.
    IntroductionChildren with severe physical disabilities are denied their fundamental right to move, restricting their development, independence, and participation in life. Brain-computer interfaces (BCIs) could enable children with complex physical needs to access power mobility (PM) devices, which could help them move safely and independently. BCIs have been studied for PM control for adults but remain unexamined in children. In this study, we explored the feasibility of BCI-enabled PM control for children with severe physical disabilities, assessing BCI performance, standard PM skills (...)
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  130.  5
    Foreign Language Learning in Older Adults: Anatomical and Cognitive Markers of Vocabulary Learning Success.Manson Cheuk-Man Fong, Matthew King-Hang Ma, Jeremy Yin To Chui, Tammy Sheung Ting Law, Nga-Yan Hui, Alma Au & William Shiyuan Wang - 2022 - Frontiers in Human Neuroscience 16.
    In recent years, foreign language learning has been proposed as a possible cognitive intervention for older adults. However, the brain network and cognitive functions underlying FLL has remained largely unconfirmed in older adults. In particular, older and younger adults have markedly different cognitive profile—while older adults tend to exhibit decline in most cognitive domains, their semantic memory usually remains intact. As such, older adults may engage the semantic functions to a larger extent than the other cognitive functions traditionally considered the (...)
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  131.  2
    The Relationship Between Affective Visual Mismatch Negativity and Interpersonal Difficulties Across Autism and Schizotypal Traits.Talitha C. Ford, Laila E. Hugrass & Bradley N. Jack - 2022 - Frontiers in Human Neuroscience 16.
    Sensory deficits are a feature of autism and schizophrenia, as well as the upper end of their non-clinical spectra. The mismatch negativity, an index of pre-attentive auditory processing, is particularly sensitive in detecting such deficits; however, little is known about the relationship between the visual MMN to facial emotions and autism and schizophrenia spectrum symptom domains. We probed the vMMN to happy, sad, and neutral faces in 61 healthy adults, and evaluated their degree of autism and schizophrenia spectrum traits using (...)
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  132.  2
    Editorial: The Functional and Neural Mechanisms of Numerosity Processing: From Perception to Cognition.Michele Fornaciai, Joonkoo Park & Roberto Arrighi - 2022 - Frontiers in Human Neuroscience 16.
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  133.  5
    Visual Occipito-Temporal N1 Sensitivity to Digits Across Elementary School.Gorka Fraga-González, Sarah V. Di Pietro, Georgette Pleisch, Susanne Walitza, Daniel Brandeis, Iliana I. Karipidis & Silvia Brem - 2022 - Frontiers in Human Neuroscience 16.
    Number processing abilities are important for academic and personal development. The course of initial specialization of ventral occipito-temporal cortex sensitivity to visual number processing is crucial for the acquisition of numeric and arithmetic skills. We examined the visual N1, the electrophysiological correlate of vOTC activation across five time points in kindergarten, middle and end of first grade, second grade, and fifth grade. A combination of cross-sectional and longitudinal EEG data of a total of 62 children at varying familial risk for (...)
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  134.  5
    Executive Functions and Impulsivity as Transdiagnostic Correlates of Psychopathology in Childhood: A Behavioral Genetic Analysis.Samantha M. Freis, Claire L. Morrison, Harry R. Smolker, Marie T. Banich, Roselinde H. Kaiser, John K. Hewitt & Naomi P. Friedman - 2022 - Frontiers in Human Neuroscience 16:863235.
    Executive functions (EFs) and impulsivity are dimensions of self-regulation that are both related to psychopathology. However, self-report measures of impulsivity and laboratory EF tasks typically display small correlations, and existing research indicates that impulsivity and EFs may tap separate aspects of self-regulation that independently statistically predict psychopathology in adulthood. However, relationships between EFs, impulsivity, and psychopathology may be different in childhood compared to adulthood. Here, we examine whether these patterns hold in the baseline assessment of the Adolescent Brain and Cognitive (...)
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  135.  5
    Automating provision of feedback to stroke patients with and without information on compensatory movements: A pilot study.Daphne Fruchter, Ronit Feingold Polak, Sigal Berman & Shelly Levy-Tzedek - 2022 - Frontiers in Human Neuroscience 16.
    Providing effective feedback to patients in a rehabilitation training program is essential. As technologies are being developed to support patient training, they need to be able to provide the users with feedback on their performance. As there are various aspects on which feedback can be given, it is important to ensure that users are not overwhelmed by too much information given too frequently by the assistive technology. We created a rule-based set of guidelines for the desired hierarchy, timing, and content (...)
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  136.  7
    The Predictive Values of Changes in Local and Remote Brain Functional Connectivity in Primary Angle-Closure Glaucoma Patients According to Support Vector Machine Analysis.Qiang Fu, Hui Liu & Yu Lin Zhong - 2022 - Frontiers in Human Neuroscience 16.
    PurposeThe primary angle-closure glaucoma is an irreversible blinding eye disease in the world. Previous neuroimaging studies demonstrated that PACG patients were associated with cerebral changes. However, the effect of optic atrophy on local and remote brain functional connectivity in PACG patients remains unknown.Materials and MethodsIn total, 23 patients with PACG and 23 well-matched Health Controls were enrolled in our study and underwent resting-state functional magnetic resonance imaging scanning. The regional homogeneity method and functional connectivity method were used to evaluate the (...)
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  137.  5
    The Affective Neuroscience of Sexuality: Development of a LUST Scale.Jürgen Fuchshuber, Emanuel Jauk, Michaela Hiebler-Ragger & Human Friedrich Unterrainer - 2022 - Frontiers in Human Neuroscience 16:853706.
    BackgroundIn recent years, there have been many studies using the Affective Neuroscience Personality Scales (ANPS) to investigate individual differences in primary emotion traits. However, in contrast to other primary emotion traits proposed by Jaak Panksepp and colleagues, there is a considerable lack of research on the LUST (L) dimension – defined as an individual’s capacity to attain sexual desire and satisfaction – a circumstance mainly caused by its exclusion from the ANPS. Therefore, this study aims to take a first step (...)
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  138.  3
    The Personal Trait of Spiritual Growth Is Correlated With the White Matter Integrity of the Brain.Masahiro Fujino, Keita Watanabe & Yoshinori Yamakawa - 2022 - Frontiers in Human Neuroscience 16.
    Determining the relationship between the entire brain structure and individual differences is important in extending healthy life expectancy, which can be affected by brain atrophy. The entire brain structure has been gradually known to be correlated not only with age but also with individual differences, such as quality of life, general intelligence, and lifestyle. However, little attention has been paid to the relationship between the entire brain structure and personal traits. We herein focused on one personal trait, namely spiritual growth, (...)
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  139.  2
    Age-Related Effects on the Spectrum of Cerebral Visual Impairment in Children With Cerebral Palsy.Jessica Galli, Erika Loi, Anna Molinaro, Stefano Calza, Alessandra Franzoni, Serena Micheletti, Andrea Rossi, Francesco Semeraro & Elisa Fazzi - 2022 - Frontiers in Human Neuroscience 16.
    BackgroundCerebral Visual Impairment is a very common finding in children affected by Cerebral Palsy. In this paper we studied the characteristics of CVI of a large group of children with CP and CVI, describing their neurovisual profiles according to three different age subgroups.MethodsWe enrolled 180 subjects with CP and CVI for the study. We carried out a demographic and clinical data collection, neurological examination, developmental or cognitive assessment, and a video-recorded visual function assessment including an evaluation of ophthalmological characteristics, oculomotor (...)
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  140.  2
    Bilingualism and Aging: Implications for (Delaying) Neurocognitive Decline.Federico Gallo, Vincent DeLuca, Yanina Prystauka, Toms Voits, Jason Rothman & Jubin Abutalebi - 2022 - Frontiers in Human Neuroscience 16.
    As a result of advances in healthcare, the worldwide average life expectancy is steadily increasing. However, this positive trend has societal and individual costs, not least because greater life expectancy is linked to higher incidence of age-related diseases, such as dementia. Over the past few decades, research has isolated various protective “healthy lifestyle” factors argued to contribute positively to cognitive aging, e.g., healthy diet, physical exercise and occupational attainment. The present article critically reviews neuroscientific evidence for another such factor, i.e., (...)
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  141.  3
    Effect of Age and Refractive Error on Local and Global Visual Perception in Chinese Children and Adolescents.Jiahe Gan, Ningli Wang, Shiming Li, Bo Wang, Mengtian Kang, Shifei Wei, Jiyuan Guo, Luoru Liu & He Li - 2022 - Frontiers in Human Neuroscience 16.
    PurposeThis study investigated the impact of age and myopia on visual form perception among Chinese school-age children.MethodsThis cross-sectional study included 1,074 students with a mean age of 12.1 ± 4.7 years. The mean spherical equivalence refraction of the participants was −1.45 ± 2.07 D. All participants underwent distance visual acuity, refraction measurement and local and global visual form perception test including orientation, parallelism, collinearity, holes and color discrimination tasks.ResultsThe reaction times of emmetropes were slower than those of myopic and high (...)
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  142.  6
    Association between prevalence rate of dementia with Lewy bodies and sleep characteristics in Chinese old adults.Jinghuan Gan, Shuai Liu, Fei Wang, Zhihong Shi, Yang Lü, Jianping Niu, Xinling Meng, Pan Cai, Xiao-Dan Wang, Zhichao Chen, Baozhi Gang & Yong Ji - 2022 - Frontiers in Human Neuroscience 16:976753.
    Introduction: Few studies are available on the prevalence and sleep-related factors of dementia with Lewy bodies (DLB) in Chinese older adults, aiming to explore the associations between sleep characteristics and DLB.Methods: A cross-sectional study with 7,528 individuals aged ≥65 years in 106 communities in Northern China was conducted from April 2019 to January 2020. Questionaries (including demographic characteristics, comorbidities, lifestyles, and sleep characteristics) were administered, and neuropsychological assessments and physical examination were conducted in phase I; screening for probable DLB was (...)
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  143.  8
    Enhanced Resting-State Functional Connectivity With Decreased Amplitude of Low-Frequency Fluctuations of the Salience Network in Mindfulness Novices.Quan Gan, Ning Ding, Guoli Bi, Ruixiang Liu, Xingrong Zhao, Jingmei Zhong, Shaoyuan Wu, Yong Zeng, Liqian Cui, Kunhua Wu, Yunfa Fu & Zhuangfei Chen - 2022 - Frontiers in Human Neuroscience 16.
    Mindfulness and accordant interventions are often used as complementary treatments to psychological or psychosomatic problems. This has also been gradually integrated into daily lives for the promotion of psychological well-being in non-clinical populations. The experience of mindful acceptance in a non-judgmental way brought about the state, which was less interfered by a negative effect. Mindfulness practice often begins with focused attention meditation restricted to an inner experience. We postulate that the brain areas related to an interoceptive function would demonstrate an (...)
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  144.  4
    Titles and Semantic Violations Affect Eye Movements When Viewing Contemporary Paintings.Joanna Ganczarek, Karolina Pietras, Anna Stolińska & Magdalena Szubielska - 2022 - Frontiers in Human Neuroscience 16.
    The role of titles in perception of visual art is a topic of interesting discussions that brings together artists, curators, and researchers. Titles provide contextual cues and guide perception. They can be particularly useful when paintings include semantic violations that make them challenging for viewers, especially viewers lacking expert knowledge. The aim of this study is to investigate the effects of titles and semantic violations on eye movements. A total of 127 participants without expertise in visual art viewed 40 paintings (...)
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  145.  7
    Neural Phenomenon in Musicality: The Interpretation of Dual-Processing Modes in Melodic Perception.Nathazsha Gande - 2022 - Frontiers in Human Neuroscience 16:823325.
    The confluence of creativity in music performance finds itself in performance practices and cultural motifs, the communication of the human body along with the instrument it interacts with, and individual performers’ perceptual, motor, and cognitive abilities that contribute to varied musical interpretations of the same piece or melodic line. The musical and artistic execution of a player, as well as the product of this phenomena can become determinant causes in a creative mental state. With advances in neurocognitive measures, the state (...)
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  146.  5
    Secure Attachment Representation in Adolescence Buffers Heart-Rate Reactivity in Response to Attachment-Related Stressors.Manuela Gander, Alexander Karabatsiakis, Katharina Nuderscher, Dorothee Bernheim, Cornelia Doyen-Waldecker & Anna Buchheim - 2022 - Frontiers in Human Neuroscience 16.
    To date, we know very little about the effects of the differences in attachment classifications on the physiological correlates of stress regulation in adolescent age groups. The present study examined for the first time heart rate and heart rate variability during an attachment interview in adolescents. HR and HRV data were collected during a baseline assessment as well as during the administration of the Adult Attachment Projective Picture System in a community-based sample of 56 adolescents. We additionally used the Adult (...)
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  147.  2
    Slow Firing Single Units Are Essential for Optimal Decoding of Silent Speech.Ananya Ganesh, Andre J. Cervantes & Philip R. Kennedy - 2022 - Frontiers in Human Neuroscience 16.
    The motivation of someone who is locked-in, that is, paralyzed and mute, is to find relief for their loss of function. The data presented in this report is part of an attempt to restore one of those lost functions, namely, speech. An essential feature of the development of a speech prosthesis is optimal decoding of patterns of recorded neural signals during silent or covert speech, that is, speaking “inside the head” with output that is inaudible due to the paralysis of (...)
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  148.  3
    A Zero-Padding Frequency Domain Convolutional Neural Network for SSVEP Classification.Dongrui Gao, Wenyin Zheng, Manqing Wang, Lutao Wang, Yi Xiao & Yongqing Zhang - 2022 - Frontiers in Human Neuroscience 16.
    The brain-computer interface of steady-state visual evoked potential is one of the fundamental ways of human-computer communication. The main challenge is that there may be a nonlinear relationship between different SSVEP in other states. For improving the performance of SSVEP BCI, a novel CNN algorithm model is proposed in this study. Based on the discrete Fourier transform to calculate the signal's power spectral density, we perform zero-padding in the signal's time domain to improve its performance on the PSD and make (...)
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  149.  2
    Retroauricular/Transcranial Color-Coded Doppler Ultrasound Approach in Junction With Ipsilateral Neck Compression on Real-Time Hydroacoustic Variation of Venous Pulsatile Tinnitus.Xiuli Gao, Yue-Lin Hsieh, Xing Wang & Wuqing Wang - 2022 - Frontiers in Human Neuroscience 16.
    Alterations in dural venous sinus hemodynamics have recently been suggested as the major contributing factors in venous pulsatile tinnitus. Nevertheless, little is known about the association between real-time alterations in hemodynamics and the subjective perception of venous PT. This study aimed to investigate the hydroacoustic correlations among diverticular vortices, mainstream sinus flow, and PT using various Doppler ultrasound techniques. Nineteen venous PT patients with protrusive diverticulum were recruited. The mainstream sinus and diverticular hemodynamics before and after ipsilateral internal jugular vein (...)
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  150.  4
    Editorial: Occupational Neuroscience: Nervous System's Health at the Workplace.Sergio Garbarino, Nicola Magnavita, Franca Barbic, Erik Valdemar Stålberg & Paola Lanteri - 2022 - Frontiers in Human Neuroscience 16.
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  151.  2
    Sleep and Temporal Lobe Epilepsy – Associations, Mechanisms and Treatment Implications.Divyani Garg, Laurel Charlesworth & Garima Shukla - 2022 - Frontiers in Human Neuroscience 16.
    In this systematic review, we aim to describe the association between temporal lobe epilepsy and sleep, with bidirectional links in mechanisms and therapeutic aspects. Sleep stages may variably impact seizure occurrence, secondary generalization and the development, frequency and distribution of interictal epileptiform discharges. Conversely, epilepsy affects sleep micro- and macroarchitecture. TLE, the most frequent form of drug resistant epilepsy, shares an enduring relationship with sleep, with some intriguing potential mechanisms specific to anatomic localization, linking the two. Sleep characteristics of TLE (...)
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  152.  6
    A scientometric analysis of the 100 most cited articles on magnetic resonance guided focused ultrasound.Kanwaljeet Garg, Manish Ranjan, Vibhor Krishna, Manmohan Singh & Ali Rezai - 2022 - Frontiers in Human Neuroscience 16:981571.
    BackgroundDiagnostic ultrasound has long been a part of a physician’s armamentarium, but transcranial focused ultrasound (FUS) is an emerging treatment of neurological disorders. Consequently, the literature in this field is increasing at a rapid pace.ObjectiveThis analysis was aimed to identify the top-cited articles on FUS to discern their origin, spread, current trends highlighting future impact of this novel neurosurgical intervention.MethodsWe searched the Web of Science database on 28th May 2021 and identified the top 100 cited articles. These articles were analyzed (...)
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  153.  5
    Past and Future Explanations for Depersonalization and Derealization Disorder: A Role for Predictive Coding.Andrew Gatus, Graham Jamieson & Bruce Stevenson - 2022 - Frontiers in Human Neuroscience 16.
    Depersonalization and derealization refer to states of dissociation in which one feels a sense of alienation in relation to one’s self and environment, respectively. Whilst transient episodes often diminish without treatment, chronic experiences of DP and DR may last for years, with common treatments lacking a strong evidence base for their efficacy. We propose a theoretical explanation of DP and DR based on interoceptive predictive coding, and discuss how transient experiences of DP and DR may be induced in the non-clinical (...)
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  154.  2
    Effects of Physical and Mental Fatigue on Postural Sway and Cortical Activity in Healthy Young Adults.Arnd Gebel, Aglaja Busch, Christine Stelzel, Tibor Hortobágyi & Urs Granacher - 2022 - Frontiers in Human Neuroscience 16.
    Physical fatigue negatively affects postural control, resulting in impaired balance performance in young and older adults. Similar effects on postural control can be observed for mental fatigue mainly in older adults. Controversial results exist for young adults. There is a void in the literature on the effects of fatigue on balance and cortical activity. Therefore, this study aimed to examine the acute effects of PF and MF on postural sway and cortical activity. Fifteen healthy young adults aged 28 ± 3 (...)
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  155.  6
    Dose-Response Transcranial Electrical Stimulation Study Design: A Well-Controlled Adaptive Seamless Bayesian Method to Illuminate Negative Valence Role in Tinnitus Perception.Iman Ghodratitoostani, Oilson A. Gonzatto, Zahra Vaziri, Alexandre C. B. Delbem, Bahador Makkiabadi, Abhishek Datta, Chris Thomas, Miguel A. Hyppolito, Antonio C. D. Santos, Francisco Louzada & João Pereira Leite - 2022 - Frontiers in Human Neuroscience 16.
    The use of transcranial Electrical Stimulation in the modulation of cognitive brain functions to improve neuropsychiatric conditions has extensively increased over the decades. tES techniques have also raised new challenges associated with study design, stimulation protocol, functional specificity, and dose-response relationship. In this paper, we addressed challenges through the emerging methodology to investigate the dose-response relationship of High Definition-transcranial Direct Current Stimulation, identifying the role of negative valence in tinnitus perception. In light of the neurofunctional testable framework and tES application, (...)
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  156.  6
    Editorial: Timing the Brain: From Basic Sciences to Clinical Implications.Giuseppe Giglia, Dimitri Ognibene, Nadia Bolognini, Marina De Tommaso, Francesco Cappello, Pierangelo Sardo, Giuseppe Ferraro & Filippo Brighina - 2022 - Frontiers in Human Neuroscience 16.
  157.  4
    A Predictive Coding Framework for Understanding Major Depression.Jessica R. Gilbert, Christina Wusinich & Carlos A. Zarate - 2022 - Frontiers in Human Neuroscience 16.
    Predictive coding models of brain processing propose that top-down cortical signals promote efficient neural signaling by carrying predictions about incoming sensory information. These “priors” serve to constrain bottom-up signal propagation where prediction errors are carried via feedforward mechanisms. Depression, traditionally viewed as a disorder characterized by negative cognitive biases, is associated with disrupted reward prediction error encoding and signaling. Accumulating evidence also suggests that depression is characterized by impaired local and long-range prediction signaling across multiple sensory domains. This review highlights (...)
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  158.  3
    Cerebellar and brainstem differences in children with developmental coordination disorder: A voxel-based morphometry study.Kamaldeep K. Gill, Donna Lang & Jill G. Zwicker - 2022 - Frontiers in Human Neuroscience 16.
    Developmental coordination disorder is a neurodevelopmental disorder that significantly impairs a child’s ability to learn motor skills and to perform everyday activities. The cause of DCD is unknown; however, evidence suggests that children with DCD have altered brain structure and function. While the cerebellum has been hypothesised to be involved in developmental coordination disorder, no studies have specifically examined cerebellar structure in this population. The purpose of our study was to examine cerebellar differences in children with DCD compared to typically-developing (...)
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  159.  3
    Congruent aero-tactile stimuli bias perception of voicing continua.Dolly Goldenberg, Mark K. Tiede, Ryan T. Bennett & D. H. Whalen - 2022 - Frontiers in Human Neuroscience 16:879981.
    Multimodal integration is the formation of a coherent percept from different sensory inputs such as vision, audition, and somatosensation. Most research on multimodal integration in speech perception has focused on audio-visual integration. In recent years, audio-tactile integration has also been investigated, and it has been established that puffs of air applied to the skin and timed with listening tasks shift the perception of voicing by naive listeners. The current study has replicated and extended these findings by testing the effect of (...)
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  160.  5
    A Preliminary Report: The Hippocampus and Surrounding Temporal Cortex of Patients With Schizophrenia Have Impaired Blood-Brain Barrier.Eric L. Goldwaser, Randel L. Swanson, Edgardo J. Arroyo, Venkat Venkataraman, Mary C. Kosciuk, Robert G. Nagele, L. Elliot Hong & Nimish K. Acharya - 2022 - Frontiers in Human Neuroscience 16.
    Though hippocampal volume reduction is a pathological hallmark of schizophrenia, the molecular pathway responsible for this degeneration remains unknown. Recent reports have suggested the potential role of impaired blood-brain barrier function in schizophrenia pathogenesis. However, direct evidence demonstrating an impaired BBB function is missing. In this preliminary study, we used immunohistochemistry and serum immunoglobulin G antibodies to investigate the state of BBB function in formalin-fixed postmortem samples from the hippocampus and surrounding temporal cortex of patients with schizophrenia and controls without (...)
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  161.  4
    Commentary: A Longitudinal Randomized Controlled Trial Protocol to Evaluate the Effects of Wuqinxi on Dynamic Functional Connectivity in Parkinson's Disease Patients.Yifan Gong, Dongli Wang & Zhibin Liu - 2022 - Frontiers in Human Neuroscience 16.
  162.  3
    Visual P2p component responds to perceived numerosity.Paolo A. Grasso, Irene Petrizzo, Camilla Caponi, Giovanni Anobile & Roberto Arrighi - 2022 - Frontiers in Human Neuroscience 16:1014703.
    Numerosity perception is a key ability for human and non-human species, probably mediated by dedicated brain mechanisms. Electrophysiological studies revealed the existence of both early and mid-latency components of the Electrophysiological (EEG) signal sensitive to numerosity changes. However, it is still unknown whether these components respond to physical or perceived variation in numerical attributes. We here tackled this point by recording electrophysiological signal while participants performed a numerosity adaptation task, a robust psychophysical method yielding changes in perceived numerosity judgments despite (...)
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  163.  1
    Anodal Transcranial Direct Current Stimulation Over Prefrontal Cortex Slows Sequence Learning in Older Adults.Brian Greeley, Jonathan S. Barnhoorn, Willem B. Verwey & Rachael D. Seidler - 2022 - Frontiers in Human Neuroscience 16.
    Aging is associated with declines in sensorimotor function. Several studies have demonstrated that transcranial direct current stimulation, a form of non-invasive brain stimulation, can be combined with training to mitigate age-related cognitive and motor declines. However, in some cases, the application of tDCS disrupts performance and learning. Here, we applied anodal tDCS either over the left prefrontal cortex, right PFC, supplementary motor complex, the left M1, or in a sham condition while older adults practiced a Discrete Sequence Production, an explicit (...)
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  164.  5
    From Expert to Elite? — Research on Top Archer’s EEG Network Topology.Feng Gu, Anmin Gong, Yi Qu, Aiyong Bao, Jin Wu, Changhao Jiang & Yunfa Fu - 2022 - Frontiers in Human Neuroscience 16.
    It is not only difficult to be a sports expert but also difficult to grow from a sports expert to a sports elite. Professional athletes are often concerned about the differences between an expert and an elite and how to eventually become an elite athlete. To explore the differences in brain neural mechanism between experts and elites in the process of motor behavior and reveal the internal connection between motor performance and brain activity, we collected and analyzed the electroencephalography findings (...)
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  165.  3
    Assessment of Agreement Between a New Application to Compute the Wisconsin Gait Score and 3-Dimensional Gait Analysis, and Reliability of the Application in Stroke Patients.Agnieszka Guzik, Andżelina Wolan-Nieroda & Mariusz Drużbicki - 2022 - Frontiers in Human Neuroscience 16.
    Currently, there are no computerized tools enabling objective interpretation of observational gait assessment based on Wisconsin Gait Scale, which is a reliable and well-tested tool. The solution envisaged by us may provide a practical tool for assessing gait deviations in patients with hemiparesis after stroke. The present study assessed agreement between a new application software for computerized WGS and 3-dimensional gait analysis, and reliability of the application. The study involved 33 individuals with hemiparesis after stroke. The software was developed based (...)
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  166.  4
    Neuromonitoring Correlates of Expertise Level in Surgical Performers: A Systematic Review.Theodore C. Hannah, Daniel Turner, Rebecca Kellner, Joshua Bederson, David Putrino & Christopher P. Kellner - 2022 - Frontiers in Human Neuroscience 16.
    Surgical expertise does not have a clear definition and is often culturally associated with power, authority, prestige, and case number rather than more objective proxies of excellence. Multiple models of expertise progression have been proposed including the Dreyfus model, however, they all currently require subjective evaluation of skill. Recently, efforts have been made to improve the ways in which surgical excellence is measured and expertise is defined using artificial intelligence, video recordings, and accelerometers. However, these aforementioned methods of assessment are (...)
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  167.  1
    The Failure of Blobology: fMRI Misinterpretation, Maleficience and Muddle.Stephen José Hanson - 2022 - Frontiers in Human Neuroscience 16.
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  168.  4
    How standardized are “standard protocols”? Variations in protocol and performance evaluation for slow cortical potential neurofeedback: A systematic review.John Hasslinger, Micaela Meregalli & Sven Bölte - 2022 - Frontiers in Human Neuroscience 16:887504.
    Neurofeedback (NF) aims to alter neural activity by enhancing self-regulation skills. Over the past decade NF has received considerable attention as a potential intervention option for many somatic and mental conditions and ADHD in particular. However, placebo-controlled trials have demonstrated insufficient superiority of NF compared to treatment as usual and sham conditions. It has been argued that the reason for limited NF effects may be attributable to participants' challenges to self-regulate the targeted neural activity. Still, there is support of NF (...)
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  169.  7
    Unilateral GPi-DBS Improves Ipsilateral and Axial Motor Symptoms in Parkinson’s Disease as Evidenced by a Brain Perfusion Single Photon Emission Computed Tomography Study.Yuka Hayashi, Takayasu Mishima, Shinsuke Fujioka, Takashi Morishita, Tooru Inoue, Shigeki Nagamachi & Yoshio Tsuboi - 2022 - Frontiers in Human Neuroscience 16.
    IntroductionDeep brain stimulation is an effective treatment for advanced Parkinson’s disease with the targeting bilateral subthalamic nucleus or globus pallidus internus. So far, detailed studies on the efficacy of unilateral STN-DBS for motor symptoms have been reported, but few studies have been conducted on unilateral GPi-DBS.Materials and MethodsSeventeen patients with Parkinson’s disease who underwent unilateral GPi-DBS were selected. We conducted comparison analyses between scores obtained 6–42 months pre- and postoperatively using the following measurement tools: the Movement Disorder Society Unified Parkinson’s (...)
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  170.  3
    A separable convolutional neural network-based fast recognition method for AR-P300.Chunzhao He, Yulin Du & Xincan Zhao - 2022 - Frontiers in Human Neuroscience 16:986928.
    Augmented reality-based brain–computer interface (AR–BCI) has a low signal-to-noise ratio (SNR) and high real-time requirements. Classical machine learning algorithms that improve the recognition accuracy through multiple averaging significantly affect the information transfer rate (ITR) of the AR–SSVEP system. In this study, a fast recognition method based on a separable convolutional neural network (SepCNN) was developed for an AR-based P300 component (AR–P300). SepCNN achieved single extraction of AR–P300 features and improved the recognition speed. A nine-target AR–P300 single-stimulus paradigm was designed to (...)
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  171.  2
    Corrigendum: Women in Neuromodulation: Innovative Contributions to Stereotactic and Functional Neurosurgery.Petra Heiden, Julia Pieczewski & Pablo Andrade - 2022 - Frontiers in Human Neuroscience 16.
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  172.  1
    Connectivity in deep brain stimulation for self-injurious behavior: multiple targets for a common network?Petra Heiden, Daniel Tim Weigel, Ricardo Loução, Christina Hamisch, Enes M. Gündüz, Maximilian I. Ruge, Jens Kuhn, Veerle Visser-Vandewalle & Pablo Andrade - 2022 - Frontiers in Human Neuroscience 16.
    Self-injurious behavior is associated with diverse psychiatric conditions. Sometimes, SIB is the most dominant symptom, severely restricting the psychosocial functioning and quality of life of the patients and inhibiting appropriate patient care. In severe cases, it can lead to permanent physical injuries or even death. Primary therapy consists of medical treatment and if implementable, behavioral therapy. For patients with severe SIB refractory to conventional therapy, neuromodulation can be considered as a last recourse. In scientific literature, several successful lesioning and deep (...)
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  173.  2
    Load-Induced Changes of Inter-Limb Asymmetries in Dynamic Postural Control in Healthy Subjects.Jessica Heil - 2022 - Frontiers in Human Neuroscience 16.
    Inter-limb asymmetries are associated with a higher potential risk for non-contact injuries. Differences in function or performance between the limbs might lead to imbalances and promote instability, increasing the potential risk for injuries. Consequently, an investigation of inter-limb asymmetries should be included in injury risk assessment. Furthermore, since non-contact injuries mainly occur under loaded conditions, an investigation of load-induced changes of inter-limb asymmetries can provide additional information on the athlete’s potential injury risk. Therefore, the current study aimed to investigate the (...)
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  174.  3
    Localization of beta power decrease as measure for lateralization in pre-surgical language mapping with magnetoencephalography, compared with functional magnetic resonance imaging and validated by Wada test.Kirsten Herfurth, Yuval Harpaz, Julie Roesch, Nadine Mueller, Katrin Walther, Martin Kaltenhaeuser, Elisabeth Pauli, Abraham Goldstein, Hajo Hamer, Michael Buchfelder, Arnd Doerfler, Julian Prell & Stefan Rampp - 2022 - Frontiers in Human Neuroscience 16:996989.
    Objective: Atypical patterns of language lateralization due to early reorganizational processes constitute a challenge in the pre-surgical evaluation of patients with pharmaco-resistant epilepsy. There is no consensus on an optimal analysis method used for the identification of language dominance in MEG. This study examines the concordance between MEG source localization of beta power desynchronization and fMRI with regard to lateralization and localization of expressive and receptive language areas using a visual verb generation task.Methods: Twenty-five patients with pharmaco-resistant epilepsy, including six (...)
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  175.  9
    Association of body mass index and its classifications with gray matter volume in individuals with a wide range of body mass index group: A whole-brain magnetic resonance imaging study.Shinsuke Hidese, Miho Ota, Junko Matsuo, Ikki Ishida, Yuuki Yokota, Kotaro Hattori, Yukihito Yomogida & Hiroshi Kunugi - 2022 - Frontiers in Human Neuroscience 16:926804.
    AimTo examine the association of body mass index (BMI) [kg/m2] and its classifications (underweight [BMI < 18.5], normal [18.5 ≤ BMI < 25], overweight [25 ≤ BMI < 30], and obese [BMI ≥ 30]) with brain structure in individuals with a wide range of BMI group.Materials and methodsThe participants included 382 right-handed individuals (mean age: 46.9 ± 14.3 years, 142 men and 240 women). The intelligence quotient was assessed using the Japanese Adult Reading Test. Voxel-based morphometry (VBM) and diffusion tensor (...)
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  176. Corrigendum: Neuromuscular Fatigue in Unimanual Handgrip Does Not Completely Affect Simultaneous Bimanual Handgrip.Mikito Hikosaka & Yu Aramaki - 2022 - Frontiers in Human Neuroscience 16.
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  177.  1
    Post-operative glioblastoma multiforme segmentation with uncertainty estimation.Michal Holtzman Gazit, Rachel Faran, Kirill Stepovoy, Oren Peles & Reuben Ruby Shamir - 2022 - Frontiers in Human Neuroscience 16:932441.
    Segmentation of post-operative glioblastoma multiforme (GBM) is essential for the planning of Tumor Treating Fields (TTFields) treatment and other clinical applications. Recent methods developed for pre-operative GBM segmentation perform poorly on post-operative GBM MRI scans. In this paper we present a method for the segmentation of GBM in post-operative patients. Our method incorporates an ensemble of segmentation networks and the Kullback–Leibler divergence agreement score in the objective function to estimate the prediction label uncertainty and cope with noisy labels and inter-observer (...)
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  178.  7
    Continuous Decoding of Hand Movement From EEG Signals Using Phase-Based Connectivity Features.Seyyed Moosa Hosseini & Vahid Shalchyan - 2022 - Frontiers in Human Neuroscience 16.
    The principal goal of the brain-computer interface is to translate brain signals into meaningful commands to control external devices or neuroprostheses to restore lost functions of patients with severe motor disabilities. The invasive recording of brain signals involves numerous health issues. Therefore, BCIs based on non-invasive recording modalities such as electroencephalography are safer and more comfortable for the patients. The BCI requires reconstructing continuous movement parameters such as position or velocity for practical application of neuroprostheses. The BCI studies in continuous (...)
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  179.  4
    Using Motor Imagery to Access Alternative Attentional Strategies When Navigating Environmental Boundaries to Prevent Freezing of Gait – A Perspective.Daniella How, Heiko Wagner & Michael Brach - 2022 - Frontiers in Human Neuroscience 16.
    Freezing of gait can cause reduced independence and quality of life for many with Parkinson’s disease. Episodes frequently occur at points of transition such as navigating a doorway. Therapeutic interventions, i.e., drugs and exercise, do not always successfully mitigate episodes. There are several different, but not exclusive causes for freezing of gait. People with freezing of gait are able to navigate dynamic situations like stairways by utilizing a different attentional strategy to over-ground walking, but may freeze when passing through a (...)
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  180.  5
    Prediction of Communication Impairment in Children With Bilateral Cerebral Palsy Using Multivariate Lesion- and Connectome-Based Approaches: Protocol for a Multicenter Prospective Cohort Study.Jie Hu, Jingjing Zhang, Yanli Yang, Ting Liang, Tingting Huang, Cheng He, Fuqin Wang, Heng Liu & Tijiang Zhang - 2022 - Frontiers in Human Neuroscience 16.
    BackgroundBilateral cerebral palsy is the most common type of CP in children and is often accompanied by different degrees of communication impairment. Several studies have attempted to identify children at high risk for communication impairment. However, most prediction factors are qualitative and subjective and may be influenced by rater bias. Individualized objective diagnostic and/or prediction methods are still lacking, and an effective method is urgently needed to guide clinical diagnosis and treatment. The aim of this study is to develop and (...)
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  181.  3
    To help others or not: A moderated mediation model of emotional dissonance.Ling Hu, Stanley Y. B. Huang, Hung-Xin Li & Shih-Chin Lee - 2022 - Frontiers in Human Neuroscience 16.
    This article proposes a moderated mediation model of emotional dissonance. In the model, emotional leadership negatively affects emotional dissonance, which, in turn, negatively affects helping behavior. Furthermore, the negative effect of emotional dissonance is assumed to be moderated by work-family conflict. Direct effects from both emotional leadership and work-family conflict to helping other behavior are also considered. Previous studies have neglected the mechanism of emotional dissonance, but this paper fills the gap with a moderated mediation model of emotional dissonance. This (...)
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  182.  5
    Altered Brain Activity in Patients With Comitant Strabismus Detected by Analysis of the Fractional Amplitude of Low-Frequency Fluctuation: A Resting-State Functional MRI Study.Meng-Yan Hu, Yi-Cong Pan, Li-Juan Zhang, Rong-Bin Liang, Qian-Min Ge, Hui-Ye Shu, Qiu-Yu Li, Chong-Gang Pei & Yi Shao - 2022 - Frontiers in Human Neuroscience 16.
    More and more studies showed that strabismus is not simply an ocular disease, but a neuro-ophthalmology disease. To analyze potential changes in brain activity and their relationship to behavioral performance in comitant strabismus patients and healthy controls. Our study recruited 28 patients with comitant strabismus and 28 people with matched weight, age range, and sex ratio as healthy controls. Using resting-state functional magnetic resonance imaging, we evaluated fALFF to compare spontaneous brain activity between comitant strabismus and healthy controls. We did (...)
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  183.  4
    Single-channel EEG signal extraction based on DWT, CEEMDAN, and ICA method.Qinghui Hu, Mingxin Li & Yunde Li - 2022 - Frontiers in Human Neuroscience 16:1010760.
    In special application scenarios, such as portable anesthesia depth monitoring, portable emotional state recognition and portable sleep monitoring, electroencephalogram (EEG) signal acquisition equipment is required to be convenient and easy to use. It is difficult to remove electrooculogram (EOG) artifacts when the number of EEG acquisition channels is small, especially when the number of observed signals is less than that of the source signals, and the overcomplete problem will arise. The independent component analysis (ICA) algorithm commonly used for artifact removal (...)
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  184.  7
    Efficacy of twice-daily high-frequency repetitive transcranial magnetic stimulation on associative memory.Qiang Hua, Yuanyuan Zhang, Qianqian Li, Xiaoran Gao, Rongrong Du, Yingru Wang, Qian Zhou, Ting Zhang, Jinmei Sun, Lei Zhang, Gong-jun Ji & Kai Wang - 2022 - Frontiers in Human Neuroscience 16:973298.
    ObjectivesSeveral studies have examined the effects of repetitive transcranial magnetic stimulation (rTMS) on associative memory (AM) but findings were inconsistent. Here, we aimed to test whether twice-daily rTMS could significantly improve AM.MethodsIn this single-blind, sham-controlled experiment, 40 participants were randomized to receive twice-daily sham or real rTMS sessions for five consecutive days (a total of 16,000 pulses). The stimulation target in left inferior parietal lobule (IPL) exhibiting peak functional connectivity to the left hippocampus was individually defined for each participant. Participants (...)
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  185.  7
    Reconfiguration of Functional Dynamics in Cortico-Thalamo-Cerebellar Circuit in Schizophrenia Following High-Frequency Repeated Transcranial Magnetic Stimulation.Huan Huang, Bei Zhang, Li Mi, Meiqing Liu, Xin Chang, Yuling Luo, Cheng Li, Hui He, Jingyu Zhou, Ruikun Yang, Hechun Li, Sisi Jiang, Dezhong Yao, Qifu Li, Mingjun Duan & Cheng Luo - 2022 - Frontiers in Human Neuroscience 16.
    Schizophrenia is a serious mental illness characterized by a disconnection between brain regions. Transcranial magnetic stimulation is a non-invasive brain intervention technique that can be used as a new and safe treatment option for patients with schizophrenia with drug-refractory symptoms, such as negative symptoms and cognitive impairment. However, the therapeutic effects of transcranial magnetic stimulation remain unclear and would be investigated using non-invasive tools, such as functional connectivity. A longitudinal design was adopted to investigate the alteration in FC dynamics using (...)
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  186.  3
    Diagnostic accuracy of multi-component spatial-temporal gait parameters in older adults with amnestic mild cognitive impairment.Shuyun Huang, Xiaobing Hou, Yajing Liu, Pan Shang, Jiali Luo, Zeping Lv, Weiping Zhang, Biqing Lin, Qiulan Huang, Shuai Tao, Yukai Wang, Chengguo Zhang, Lushi Chen, Suyue Pan & Haiqun Xie - 2022 - Frontiers in Human Neuroscience 16:911607.
    ObjectiveThis study aimed to develop a diagnostic model of multi-kinematic parameters for patients with amnestic mild cognitive impairment (aMCI).MethodIn this cross-sectional study, 94 older adults were included (33 cognitively normal, CN; and 61 aMCI). We conducted neuropsychological battery tests, such as global cognition and cognitive domains, and collected gait parameters by an inertial-sensor gait analysis system. Multivariable regression models were used to identify the potential diagnostic variables for aMCI. Receiver operating characteristic (ROC) curves were applied to assess the diagnostic accuracy (...)
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  187.  2
    Effects of Transcranial Direct Current Stimulation Over the Left Primary Motor Cortex on Verbal Intelligence.Yifan Huang, Yinling Zhang, Yizhe Zhang & Xiaoqin Mai - 2022 - Frontiers in Human Neuroscience 16.
    Previous studies have shown that changes in gray matter density and volume in the left primary motor cortex are significantly associated with changes in individuals’ verbal intelligence quotient, but not with their performance intelligence quotient. In the present study, we examined the effects of transcranial direct current stimulation over the left primary motor cortex on performance in intelligence tests. We chose four subtests of the Wechsler Adult Intelligence Scale-Chinese Revised version and randomized participants into anodal, cathodal, and sham groups. We (...)
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  188.  3
    Psychoanalytical Considerations of Emotion Regulation Disorders in Multiple Complex-Traumatized Children—A Study Protocol of the Prospective Study MuKi.Felicitas Hug, Tom Degen, Patrick Meurs & Tamara Fischmann - 2022 - Frontiers in Human Neuroscience 16.
    Studies in adults with mental disorders suggest that the experience of early and chronic trauma is associated with changes in reward expectancy and processing. In addition, severe childhood trauma has been shown to contribute to the development of mental disorders in general. Data on effects of early childhood trauma on reward expectancy and processing in middle childhood currently appear insufficient. The present study aims to fill this research gap by examining the effects of developmental trauma disorder on reward expectancy and (...)
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  189.  6
    Challenges of brain-computer interface facilitated cognitive assessment for children with cerebral palsy.Jane E. Huggins, Petra Karlsson & Seth A. Warschausky - 2022 - Frontiers in Human Neuroscience 16:977042.
    Brain-computer interfaces (BCIs) have been successfully used by adults, but little information is available on BCI use by children, especially children with severe multiple impairments who may need technology to facilitate communication. Here we discuss the challenges of using non-invasive BCI with children, especially children who do not have another established method of communication with unfamiliar partners. Strategies to manage these challenges require consideration of multiple factors related to accessibility, cognition, and participation. These factors include decisions regarding where (home, clinic, (...)
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  190.  4
    Finding Cortical Subregions Regarding the Dorsal Language Pathway Based on the Structural Connectivity.Young-Eun Hwang, Young-Bo Kim & Young-Don Son - 2022 - Frontiers in Human Neuroscience 16.
    Although the language-related fiber pathways in the human brain, such as the superior longitudinal fasciculus and arcuate fasciculus, are already well-known, understanding more sophisticated cortical regions connected by the fiber tracts is essential to scrutinize the structural connectivity of language circuits. With the regions of interest that were selected based on the Brainnetome atlas, the fiber orientation distribution estimation method for tractography was used to produce further elaborate connectivity information. The results indicated that both fiber bundles had two distinct connections (...)
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  191.  3
    Motor Cortex Response to Pleasant Odor Perception and Imagery: The Differential Role of Personality Dimensions and Imagery Ability.Carmenrita Infortuna, Francesca Gualano, David Freedberg, Sapan P. Patel, Asad M. Sheikh, Maria Rosaria Anna Muscatello, Antonio Bruno, Carmela Mento, Eileen Chusid, Zhiyong Han, Florian P. Thomas & Fortunato Battaglia - 2022 - Frontiers in Human Neuroscience 16.
    BackgroundNeuroimaging studies have shown a complex pattern of brain activation during perception of a pleasant odor and during its olfactory imagery. To date, little is known regarding changes in motor cortex excitability during these tasks. Bergamot essential oil is extensively used in perfumes and cosmetics for its pleasantness. Therefore, to further our understanding of the human sense of smell, this study aimed to investigate the effect of perception and imagery of a pleasant odor on motor cortex using Transcranial magnetic stimulation.Materials (...)
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  192.  3
    Editorial: Cognitive reserve, cognitive functioning, and mental health in elderly people.Tatiana Quarti Irigaray, Carmen Moret-Tatay, Mike Murphy & Camila Rosa de Oliveira - 2022 - Frontiers in Human Neuroscience 16:1040675.
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  193.  2
    Motor Learning in Response to Different Experimental Pain Models Among Healthy Individuals: A Systematic Review.Mohammad Izadi, Sae Franklin, Marianna Bellafiore & David W. Franklin - 2022 - Frontiers in Human Neuroscience 16.
    Learning new movement patterns is a normal part of daily life, but of critical importance in both sport and rehabilitation. A major question is how different sensory signals are integrated together to give rise to motor adaptation and learning. More specifically, there is growing evidence that pain can give rise to alterations in the learning process. Despite a number of studies investigating the role of pain on the learning process, there is still no systematic review to summarize and critically assess (...)
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  194.  4
    Behavioral Experience-Sampling Methods in Neuroimaging Studies With Movie and Narrative Stimuli.Iiro P. Jääskeläinen, Jyrki Ahveninen, Vasily Klucharev, Anna N. Shestakova & Jonathan Levy - 2022 - Frontiers in Human Neuroscience 16.
    Movies and narratives are increasingly utilized as stimuli in functional magnetic resonance imaging, magnetoencephalography, and electroencephalography studies. Emotional reactions of subjects, what they pay attention to, what they memorize, and their cognitive interpretations are all examples of inner experiences that can differ between subjects during watching of movies and listening to narratives inside the scanner. Here, we review literature indicating that behavioral measures of inner experiences play an integral role in this new research paradigm via guiding neuroimaging analysis. We review (...)
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  195.  2
    Contrast reversal of the iris and sclera increases the face sensitive N170.Kelly J. Jantzen, Nicole McNamara, Adam Harris, Anna Schubert, Michael Brooks, Matthew Seifert & Lawrence A. Symons - 2022 - Frontiers in Human Neuroscience 16:987217.
    Previous research has demonstrated that reversing the contrast of the eye region, which includes the eyebrows, affects the N170 ERP. To selectively assess the impact of just the eyes, the present study evaluated the N170 in response to reversing contrast polarity of just the iris and sclera in upright and inverted face stimuli. Contrast reversal of the eyes increased the amplitude of the N170 for upright faces, but not for inverted faces, suggesting that the contrast of eyes is an important (...)
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  196.  7
    Exploration of abnormal dynamic spontaneous brain activity in patients with high myopia via dynamic regional homogeneity analysis.Yu Ji, Qi Cheng, Wen-wen Fu, Pei-pei Zhong, Shui-qin Huang, Xiao-lin Chen & Xiao-Rong Wu - 2022 - Frontiers in Human Neuroscience 16.
    AimPatients with high myopia reportedly exhibit changes in functional brain activity, but the mechanism underlying such changes is unclear. This study was conducted to observe differences in dynamic spontaneous brain activity between patients with HM and healthy controls via dynamic regional homogeneity analysis.MethodsResting-state functional magnetic resonance imaging scans were performed on 82 patients with HM and 59 HCs who were closely matched for age, sex, and weight. The dReHo approach was used to assess local dynamic activity in the human brain. (...)
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  197.  8
    Abnormal Large-Scale Neuronal Network in High Myopia.Yu Ji, Ling Shi, Qi Cheng, Wen-wen Fu, Pei-pei Zhong, Shui-qin Huang, Xiao-lin Chen & Xiao-Rong Wu - 2022 - Frontiers in Human Neuroscience 16.
    AimResting state functional magnetic resonance imaging was used to analyze changes in functional connectivity within various brain networks and functional network connectivity among various brain regions in patients with high myopia.Methodsrs-fMRI was used to scan 82 patients with HM and 59 healthy control volunteers matched for age, sex, and education level. Fourteen resting state networks were extracted, of which 11 were positive. Then, the FCs and FNCs of RSNs in HM patients were examined by independent component analysis.ResultsCompared with the HC (...)
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  198.  6
    A Hybrid Brain-Computer Interface Based on Visual Evoked Potential and Pupillary Response.Lu Jiang, Xiaoyang Li, Weihua Pei, Xiaorong Gao & Yijun Wang - 2022 - Frontiers in Human Neuroscience 16.
    Brain-computer interface based on steady-state visual evoked potential has been widely studied due to the high information transfer rate, little user training, and wide subject applicability. However, there are also disadvantages such as visual discomfort and “BCI illiteracy.” To address these problems, this study proposes to use low-frequency stimulations, which can simultaneously elicit visual evoked potential and pupillary response to construct a hybrid BCI system. Classification accuracy was calculated using supervised and unsupervised methods, respectively, and the hybrid accuracy was obtained (...)
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  199.  6
    The Neural Basis of Moral Judgement for Self and for Others: Evidence From Event-Related Potentials.Qin Jiang, Linglin Zhuo, Qi Wang & Wenxia Lin - 2022 - Frontiers in Human Neuroscience 16.
    Developmental and neuroscience works have demonstrated that the moral judgment is influenced by theory of mind, which refers to the ability to represent the mental states of different agents. However, the neural and cognitive time course of interactions between moral judgment and ToM remains unclear. The present event-related potential study investigated the underlying neural substrate of the interaction between moral judgment and ToM by contrasting the ERPs elicited by moral judgments for self and for others in moral dilemmas. In classic (...)
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  200.  7
    Altered Neuromagnetic Activity in Persistent Postural-Perceptual Dizziness: A Multifrequency Magnetoencephalography Study.Weiwei Jiang, Jintao Sun, Jing Xiang, Yulei Sun, Lu Tang, Ke Zhang, Qiqi Chen & Xiaoshan Wang - 2022 - Frontiers in Human Neuroscience 16.
    ObjectiveThe aim of our study was to investigate abnormal changes in brain activity in patients with persistent postural-perceptual dizziness using magnetoencephalography.MethodsMagnetoencephalography recordings from 18 PPPD patients and 18 healthy controls were analyzed to determine the source of brain activity in seven frequency ranges using accumulated source imaging.ResultsOur study showed that significant changes in the patterns of localization in the temporal-parietal junction were observed at 1–4, 4–8, and 12–30 Hz in PPPD patients compared with healthy controls, and changes in the frontal (...)
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  201.  5
    More Than Just Statics: Temporal Dynamic Changes in Inter- and Intrahemispheric Functional Connectivity in First-Episode, Drug-Naive Patients With Major Depressive Disorder.Yu Jiang, Yuan Chen, Ruiping Zheng, Bingqian Zhou, Ying Wei, Ankang Gao, Yarui Wei, Shuying Li, Jinxia Guo, Shaoqiang Han, Yong Zhang & Jingliang Cheng - 2022 - Frontiers in Human Neuroscience 16.
    Several functional magnetic resonance imaging studies have demonstrated abnormalities in static intra- and interhemispheric functional connectivity among diverse brain regions in patients with major depressive disorder. However, the dynamic changes in intra- and interhemispheric functional connectivity patterns in patients with MDD remain unclear. Fifty-eight first-episode, drug-naive patients with MDD and 48 age-, sex-, and education level-matched healthy controls underwent resting-state fMRI. Whole-brain functional connectivity, analyzed using the functional connectivity density approach, was decomposed into ipsilateral and contralateral functional connectivity. We computed (...)
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  202.  7
    Longitudinal neurological analysis of moderate and severe pediatric cerebral visual impairment.Andres Jimenez-Gomez, Kristen S. Fisher, Kevin X. Zhang, Chunyan Liu, Qin Sun & Veeral S. Shah - 2022 - Frontiers in Human Neuroscience 16.
    IntroductionCerebral visual impairment results from damage to cerebral visual processing structures. It is the most common cause of pediatric visual impairment in developed countries and rising in prevalence in developing nations. There is currently limited understanding on how neurologic, developmental, and ophthalmic factors predict outcome for pediatric CVI.MethodA retrospective manual chart review of pediatric CVI patients seen at the tertiary pediatric hospital neurology and neuro-ophthalmology service between 2010 and 2019 was conducted. Patients were stratified into severity groups, and followed over (...)
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  203.  4
    Repetitive Transcranial Magnetic Stimulation Induces Quantified Functional and Structural Changes in Subcortical Stroke: A Combined Arterial Spin Labeling Perfusion and Diffusion Tensor Imaging Study.Yu Jin, Xi Bai, Binghu Jiang, Zhiwei Guo & Qiwen Mu - 2022 - Frontiers in Human Neuroscience 16.
    PurposeTo explore the changes of cerebral blood flow and fractional anisotropy in stroke patients with motor dysfunction after repetitive transcranial magnetic stimulation treatment, and to better understand the role of rTMS on motor rehabilitation of subcortical stroke patients from the perfusion and structural level.Materials and MethodsIn total, 23 first-episode acute ischemic stroke patients and sixteen healthy controls were included. The patients were divided into the rTMS and sham group. The rehabilitation assessments and examination of perfusion and structural MRI were performed (...)
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  204.  5
    HD-tDCS of primary and higher-order motor cortex affects action word processing.Karim Johari, Nicholas Riccardi, Svetlana Malyutina, Mirage Modi & Rutvik H. Desai - 2022 - Frontiers in Human Neuroscience 16:959455.
    The contribution of action-perception systems of the brain to lexical semantics remains controversial. Here, we used high-definition transcranial direct current stimulation (HD-tDCS) in healthy adults to examine the role of primary (left hand motor area; HMA) and higher-order (left anterior inferior parietal lobe; aIPL) action areas in action-related word processing (action verbs and manipulable nouns) compared to non-action-related control words (non-action verbs and non-manipulable nouns). We investigated stimulation-related effects at three levels of semantic processing: subliminal, implicit, and explicit. Broadly, we (...)
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  205.  9
    Hypersensitivity to passive voice hearing in hallucination proneness.Joseph F. Johnson, Michel Belyk, Michael Schwartze, Ana P. Pinheiro & Sonja A. Kotz - 2022 - Frontiers in Human Neuroscience 16.
    Voices are a complex and rich acoustic signal processed in an extensive cortical brain network. Specialized regions within this network support voice perception and production and may be differentially affected in pathological voice processing. For example, the experience of hallucinating voices has been linked to hyperactivity in temporal and extra-temporal voice areas, possibly extending into regions associated with vocalization. Predominant self-monitoring hypotheses ascribe a primary role of voice production regions to auditory verbal hallucinations. Alternative postulations view a generalized perceptual salience (...)
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  206.  2
    Task-Based Functional Connectivity and Blood-Oxygen-Level-Dependent Activation During Within-Scanner Performance of Lumbopelvic Motor Tasks: A Functional Magnetic Resonance Imaging Study.Max K. Jordon, Jill Campbell Stewart, Sheri P. Silfies & Paul F. Beattie - 2022 - Frontiers in Human Neuroscience 16.
    There are a limited number of neuroimaging investigations into motor control of the lumbopelvic musculature. Most investigation examining motor control of the lumbopelvic musculature utilize transcranial magnetic stimulation and focus primarily on the motor cortex. This has resulted in a dearth of knowledge as it relates to how other regions of the brain activate during lumbopelvic movement. Additionally, task-based functional connectivity during lumbopelvic movements has not been well elucidated. Therefore, we used functional magnetic resonance imaging to examine brain activation and (...)
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  207.  2
    Identifying neural correlates of multidimensional, subjective gaming experiences during active gameplay.Uijong Ju - 2022 - Frontiers in Human Neuroscience 16:1013991.
    Studying how gaming experiences are encoded is important to understand the effects of gaming on the brain. Although studies have investigated neural correlates of gaming experiences, the brain patterns related to the full range of subjective experiences across different types of games are yet to be identified. The present study used three custom-made, immersive driving games with different input dynamics (controlling a car, a boat, or a spaceship) and different mechanics to assess subjective gaming experiences in a magnetic resonance imaging (...)
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  208.  5
    Changes in corticospinal and spinal reflex excitability through functional electrical stimulation with and without observation and imagination of walking.Naotsugu Kaneko, Atsushi Sasaki, Hikaru Yokoyama, Yohei Masugi & Kimitaka Nakazawa - 2022 - Frontiers in Human Neuroscience 16:994138.
    Functional electrical stimulation (FES), a method for inducing muscle contraction, has been successfully used in gait rehabilitation for patients with deficits after neurological disorders and several clinical studies have found that it can improve gait function after stroke and spinal cord injury. However, FES gait training is not suitable for patients with walking difficulty, such as those with severe motor paralysis of the lower limbs. We have previously shown that action observation combined with motor imagery (AO + MI) of walking (...)
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  209.  6
    Why do mothers never stop grieving for their deceased children? Enduring alterations of brain connectivity and function.Sarah M. Kark, Joren G. Adams, Mithra Sathishkumar, Steven J. Granger, Liv McMillan, Tallie Z. Baram & Michael A. Yassa - 2022 - Frontiers in Human Neuroscience 16:925242.
    A child’s death is a profound loss for mothers and affects hundreds of thousands of women. Mothers report inconsolable and progressive grief that is distinct from depression and impacts daily emotions and functions. The brain mechanisms responsible for this relatively common and profound mental health problem are unclear, hampering its clinical recognition and care. In an initial exploration of this condition, we used resting state functional MRI (fMRI) scans to examine functional connectivity in key circuits, and task-based fMRI to examine (...)
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  210.  5
    Epileptogenic high-frequency oscillations present larger amplitude both in mesial temporal and neocortical regions.Victor Karpychev, Alexandra Balatskaya, Nikita Utyashev, Nikita Pedyash, Andrey Zuev, Olga Dragoy & Tommaso Fedele - 2022 - Frontiers in Human Neuroscience 16:984306.
    High-frequency oscillations (HFO) are a promising biomarker for the identification of epileptogenic tissue. While HFO rates have been shown to predict seizure outcome, it is not yet clear whether their morphological features might improve this prediction. We validated HFO rates against seizure outcome and delineated the distribution of HFO morphological features. We collected stereo-EEG recordings from 20 patients (231 electrodes; 1,943 contacts). We computed HFO rates (the co-occurrence of ripples and fast ripples) through a validated automated detector during non-rapid eye (...)
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  211.  4
    Variation of cerebrospinal fluid in specific regions regulates focality in transcranial direct current stimulation.Rajan Kashyap, Sagarika Bhattacharjee, Rose Dawn Bharath, Ganesan Venkatasubramanian, Kaviraja Udupa, Shahid Bashir, Kenichi Oishi, John E. Desmond, S. H. Annabel Chen & Cuntai Guan - 2022 - Frontiers in Human Neuroscience 16:952602.
    BackgroundConventionally, transcranial direct current stimulation (tDCS) aims to focalize the current reaching the target region-of-interest (ROI). The focality can be quantified by the dose-target-determination-index (DTDI). Despite having a uniform tDCS setup, some individuals receive focal stimulation (high DTDI) while others show reduced focality (“non-focal”). The volume of cerebrospinal fluid (CSF), gray matter (GM), and white matter (WM) underlying each ROI govern the tDCS current distribution inside the brain, thereby regulating focality.AimTo determine the regional volume parameters that differentiate the focal and (...)
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  212.  3
    Effects of a new speech support application on intensive speech therapy and changes in functional brain connectivity in patients with post-stroke aphasia.Yuta Katsuno, Yoshino Ueki, Keiichi Ito, Satona Murakami, Kiminori Aoyama, Naoya Oishi, Hirohito Kan, Noriyuki Matsukawa, Katashi Nagao & Hiroshi Tatsumi - 2022 - Frontiers in Human Neuroscience 16:870733.
    Aphasia is a language disorder that occurs after a stroke and impairs listening, speaking, reading, writing, and calculation skills. Patients with post-stroke aphasia in Japan are increasing due to population aging and the advancement of medical treatment. Opportunities for adequate speech therapy in chronic stroke are limited due to time constraints. Recent studies have reported that intensive speech therapy for a short period of time or continuous speech therapy using high-tech equipment, including speech applications (apps, can improve aphasia even in (...)
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  213.  2
    Activation of human spinal locomotor circuitry using transvertebral magnetic stimulation.Kazutake Kawai, Toshiki Tazoe, Toshimasa Yanai, Kazuyuki Kanosue & Yukio Nishimura - 2022 - Frontiers in Human Neuroscience 16:1016064.
    Transvertebral magnetic stimulation (TVMS) of the human lumbar spinal cord can evoke bilateral rhythmic leg movements, as in walking, supposedly through the activation of spinal locomotor neural circuitry. However, an appropriate stimulus intensity that can effectively drive the human spinal locomotor circuitry to evoke walking-like movements has not been determined. To address this issue, TVMS was delivered over an intervertebral space of the lumbar cord (L1–L3) at different stimulus intensities (10–70% of maximum stimulator output) in healthy human adults. In a (...)
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  214.  2
    Quantitatively characterizing reflexive responses to pitch perturbations.Elaine Kearney, Alfonso Nieto-Castañón, Riccardo Falsini, Ayoub Daliri, Elizabeth S. Heller Murray, Dante J. Smith & Frank H. Guenther - 2022 - Frontiers in Human Neuroscience 16:929687.
    BackgroundReflexive pitch perturbation experiments are commonly used to investigate the neural mechanisms underlying vocal motor control. In these experiments, the fundamental frequency–the acoustic correlate of pitch–of a speech signal is shifted unexpectedly and played back to the speaker via headphones in near real-time. In response to the shift, speakers increase or decrease their fundamental frequency in the direction opposing the shift so that their perceived pitch is closer to what they intended. The goal of the current work is to develop (...)
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  215.  3
    Revisiting the relation between syntax, action, and left BA44.David Kemmerer - 2022 - Frontiers in Human Neuroscience 16:923022.
    Among the many lines of research that have been exploring how embodiment contributes to cognition, one focuses on how the neural substrates of language may be shared, or at least closely coupled, with those of action. This paper revisits a particular proposal that has received considerable attention—namely, that the forms of hierarchical sequencing that characterize both linguistic syntax and goal-directed action are underpinned partly by common mechanisms in left Brodmann area (BA) 44, a cortical region that is not only classically (...)
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  216.  2
    Recruitment and Differential Firing Patterns of Single Units During Conditioning to a Tone in a Mute Locked-In Human.Philip Kennedy & Andre J. Cervantes - 2022 - Frontiers in Human Neuroscience 16:864983.
    Single units that are not related to the desired task can become related to the task by conditioning their firing rates. We theorized that, during conditioning of firing rates to a tone, (a) unrelated single units would be recruited to the task; (b) the recruitment would depend on the phase of the task; (c) tones of different frequencies would produce different patterns of single unit recruitment. In our mute locked-in participant, we conditioned single units using tones of different frequencies emitted (...)
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  217.  7
    Spatial and Temporal Distribution of Information Processing in the Human Dorsal Anterior Cingulate Cortex.Conor Keogh, Alceste Deli, Amir Puyan Divanbeighi Zand, Mark Jernej Zorman, Sandra G. Boccard-Binet, Matthew Parrott, Charalampos Sigalas, Alexander R. Weiss, John Frederick Stein, James J. FitzGerald, Tipu Z. Aziz, Alexander L. Green & Martin John Gillies - 2022 - Frontiers in Human Neuroscience 16.
    The dorsal anterior cingulate cortex is a key node in the human salience network. It has been ascribed motor, pain-processing and affective functions. However, the dynamics of information flow in this complex region and how it responds to inputs remain unclear and are difficult to study using non-invasive electrophysiology. The area is targeted by neurosurgery to treat neuropathic pain. During deep brain stimulation surgery, we recorded local field potentials from this region in humans during a decision-making task requiring motor output. (...)
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  218.  6
    Brain–Heart Interaction and the Experience of Flow While Playing a Video Game.Shiva Khoshnoud, Federico Alvarez Igarzábal & Marc Wittmann - 2022 - Frontiers in Human Neuroscience 16.
    The flow state – an experience of complete absorption in an activity – is linked with less self-referential processing and increased arousal. We used the heart-evoked potential, an index representing brain–heart interaction, as well as indices of peripheral physiology to assess the state of flow in individuals playing a video game. 22 gamers and 21 non-gamers played the video game Thumper for 25 min while their brain and cardiorespiratory signals were simultaneously recorded. The more participants were absorbed in the game, (...)
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  219.  4
    Electronic Cigarette Vaping Did Not Enhance the Neural Process of Working Memory for Regular Cigarette Smokers.Dong-Youl Kim, Yujin Jang, Da-Woon Heo, Sungman Jo, Hyun-Chul Kim & Jong-Hwan Lee - 2022 - Frontiers in Human Neuroscience 16.
    BackgroundElectronic cigarettes as substitute devices for regular tobacco cigarettes have been increasing in recent times. We investigated neuronal substrates of vaping e-cigs and smoking r-cigs from r-cig smokers.MethodsTwenty-two r-cig smokers made two visits following overnight smoking cessation. Functional magnetic resonance imaging data were acquired while participants watched smoking images. Participants were then allowed to smoke either an e-cig or r-cig until satiated and fMRI data were acquired. Their craving levels and performance on the Montreal Imaging Stress Task and a 3-back (...)
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  220.  5
    Frontal lobe hemodynamics detected by functional near-infrared spectroscopy during head-up tilt table tests in patients with electrical burns.Yoo Hwan Kim, Youngmin Kim, Jaechul Yoon, Yong Suk Cho, Dohern Kym, Jun Hur, Wook Chun & Byung-Jo Kim - 2022 - Frontiers in Human Neuroscience 16:986230.
    SignificanceElectrical burns can cause severe damage to the nervous system, resulting in autonomic dysfunction with reduced cerebral perfusion. However, few studies have investigated these consequences.AimTo elucidate changes in prefrontal cerebral hemodynamics using functional near-infrared spectroscopy (fNIRS) during the head-up tilt table test (HUT) for patients with electrical burns.ApproachWe recruited 17 patients with acute electrical burns within 1 week after their accidents and 10 healthy volunteers. The NIRS parameters acquired using an fNIRS device attached to the forehead were analyzed in five (...)
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  221.  2
    External walking environment differentially affects muscle synergies in children with cerebral palsy and typical development.Yushin Kim, Thomas C. Bulea & Diane L. Damiano - 2022 - Frontiers in Human Neuroscience 16:976100.
    Despite external environmental changes in walking, such as manipulating gait speed, previous studies have shown that the underlying muscle synergy structures (synergy weights or vectors) rarely vary. The purpose of this study is to examine if external environmental changes to the walking task influence muscle synergies in children with cerebral palsy (CP) and/or typical development (TD). To identify muscle synergies, we extracted muscle synergies from eight children with CP and eight age-matched TD in three treadmill walking conditions, e.g., baseline (adjusted (...)
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  222.  4
    Safety of deep brain stimulation in pregnancy: A comprehensive review.Caroline King, T. Maxwell Parker, Kay Roussos-Ross, Adolfo Ramirez-Zamora, John C. Smulian, Michael S. Okun & Joshua K. Wong - 2022 - Frontiers in Human Neuroscience 16:997552.
    IntroductionDeep brain stimulation (DBS) is increasingly used to treat the symptoms of various neurologic and psychiatric conditions. People can undergo the procedure during reproductive years but the safety of DBS in pregnancy remains relatively unknown given the paucity of published cases. We thus conducted a review of the literature to determine the state of current knowledge about DBS in pregnancy and to determine how eligibility criteria are approached in clinical trials with respect to pregnancy and the potential for pregnancy.MethodsA literature (...)
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  223. Infra Low Frequency Neurofeedback Training for Trauma Recovery: A Case Report.Hanno W. Kirk & Monica Geers Dahl - 2022 - Frontiers in Human Neuroscience 16.
    This paper reviews how and why ILF Neurofeedback has proven to be a parsimonious and efficient way to remediate the neuro-physiological effects of trauma. Reference is made to several large- and small-scale institutional proof of concept experimental studies each addressing a specific kind of trauma. It ends with a case report by the author working with an American combat veteran. It makes the argument that given its success that ILF Neurofeedback and Alpha-Theta training become accepted as part of an integrative (...)
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  224.  13
    What Neuroscientists Think, and Don’t Think, About Consciousness.Peter D. Kitchener & Colin G. Hales - 2022 - Frontiers in Human Neuroscience 16.
    The approach the majority of neuroscientists take to the question of how consciousness is generated, it is probably fair to say, is to ignore it. Although there are active research programs looking at correlates of consciousness, and explorations of informational properties of what might be relevant neural ensembles, the tacitly implied mechanism of consciousness in these approaches is that it somehow just happens. This reliance on a “magical emergence” of consciousness does not address the “objectively unreasonable” proposition that elements that (...)
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  225.  4
    Target-Related Alpha Attenuation in a Brain-Computer Interface Rapid Serial Visual Presentation Calibration.Daniel Klee, Tab Memmott, Niklas Smedemark-Margulies, Basak Celik, Deniz Erdogmus & Barry S. Oken - 2022 - Frontiers in Human Neuroscience 16.
    This study evaluated the feasibility of using occipitoparietal alpha activity to drive target/non-target classification in a brain-computer interface for communication. EEG data were collected from 12 participants who completed BCI Rapid Serial Visual Presentation calibrations at two different presentation rates: 1 and 4 Hz. Attention-related changes in posterior alpha activity were compared to two event-related potentials : N200 and P300. Machine learning approaches evaluated target/non-target classification accuracy using alpha activity. Results indicated significant alpha attenuation following target letters at both 1 (...)
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  226.  2
    Follow the sound of my violin: Granger causality reflects information flow in sound.Lucas Klein, Emily A. Wood, Dan Bosnyak & Laurel J. Trainor - 2022 - Frontiers in Human Neuroscience 16:982177.
    Recent research into how musicians coordinate their expressive timing, phrasing, articulation, dynamics, and other stylistic characteristics during performances has highlighted the role of predictive processes, as musicians must anticipate how their partners will play in order to be together. Several studies have used information flow techniques such as Granger causality to show that upcoming movements of a musician can be predicted from immediate past movements of fellow musicians. Although musicians must move to play their instruments, a major goal of music (...)
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  227.  4
    Comparison of visual requirements and regulations for obtaining a driving license in different European countries and some open questions on their adequacy.Nina Kobal & Marko Hawlina - 2022 - Frontiers in Human Neuroscience 16:927712.
    We reviewed the current state of knowledge regarding visual function and its suitability as part of medical examinations for driving licenses. We focused only on Group 1 drivers. According to previous studies, visual acuity, which is the most common test, is weakly associated with a higher risk of road accidents, with a greater role of visual field. The inclusion of the visual field test in medical examinations is therefore important, but the actual limit value is still unclear and further research (...)
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  228.  6
    Measurement Accuracy of Freezing of Gait Scoring Based on Videos.Yuki Kondo, Katsuhiro Mizuno, Kyota Bando, Ippei Suzuki, Takuya Nakamura, Shusei Hashide, Hideki Kadone & Kenji Suzuki - 2022 - Frontiers in Human Neuroscience 16.
    Freezing of gait is a common symptom in the late stages of Parkinson’s disease and related disorders. Videos are the gold standard method to conduct FOG scoring; however, the measurement accuracy of FOG scoring based on videos has not been formally assessed, despite its use in previous studies. This study aimed to calculate the measurement accuracy of video-based FOG scoring. Three evaluators scored the FOG based on 157 video data points collected from 21 patients using an annotation tool. One evaluator (...)
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  229.  3
    Understanding the Neural Basis of Prospective Memory Using Functional Near-Infrared Spectroscopy.Yu Wen Koo, David L. Neumann, Tamara Ownsworth, Michael K. Yeung & David H. K. Shum - 2022 - Frontiers in Human Neuroscience 16.
    Prospective memory is the ability to perform a planned action at an intended future time. This study examined the neural correlates of PM using functional near-infrared spectroscopy. This study employed a within-participants design. A laboratory PM task was adapted for use with fNIRS to investigate regions of interest and levels of brain activation during task performance in 32 participants. Participants first completed a working memory task followed by a WM plus PM task while neural activity was measured using fNIRS. Behavioral (...)
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  230.  11
    Rhythms of human attention and memory: An embedded process perspective.Moritz Köster & Thomas Gruber - 2022 - Frontiers in Human Neuroscience 16:905837.
    It remains a dogma in cognitive neuroscience to separate human attention and memory into distinct modules and processes. Here we propose that brain rhythms reflect the embedded nature of these processes in the human brain, as evident from their shared neural signatures: gamma oscillations (30–90 Hz) reflect sensory information processing and activated neural representations (memory items). The theta rhythm (3–8 Hz) is a pacemaker of explicit control processes (central executive), structuring neural information processing, bit by bit, as reflected in the (...)
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  231.  9
    Researchers’ Ethical Concerns About Using Adaptive Deep Brain Stimulation for Enhancement.Kristin Kostick-Quenet, Lavina Kalwani, Barbara Koenig, Laura Torgerson, Clarissa Sanchez, Katrina Munoz, Rebecca L. Hsu, Demetrio Sierra-Mercado, Jill Oliver Robinson, Simon Outram, Stacey Pereira, Amy McGuire, Peter Zuk & Gabriel Lazaro-Munoz - 2022 - Frontiers in Human Neuroscience 16.
    The capacity of next-generation closed-loop or adaptive deep brain stimulation devices to read and write shows great potential to effectively manage movement, seizure, and psychiatric disorders, and also raises the possibility of using aDBS to electively modulate mood, cognition, and prosociality. What separates aDBS from most neurotechnologies currently used for enhancement is that aDBS remains an invasive, surgically-implanted technology with a risk-benefit ratio significantly different when applied to diseased versus non-diseased individuals. Despite a large discourse about the ethics of enhancement, (...)
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