The basis of science is the hypothetico-deductive method and the recording of experiments in sufficient detail to enable reproducibility. We report the development of Robot Scientist "Adam," which advances the automation of both. Adam has autonomously generated functional genomics hypotheses about the yeast Saccharomyces cerevisiae and experimentally tested these hypotheses by using laboratory automation. We have confirmed Adam's conclusions through manual experiments. To describe Adam's research, we have developed an ontology and logical language. The resulting formalization involves over 10,000 different (...) research units in a nested treelike structure, 10 levels deep, that relates the 6.6 million biomass measurements to their logical description. This formalization describes how a machine contributed to scientific knowledge. (shrink)
Wolicka's book on Being and Sign, which deals with semiotics of John of St. Thomas, can serve as a typical model of the approach to the Thomistic philosophy as it is practiced by the KUL's School of Philosophy, namely, "in its close cooperation between the chairs of metaphysics, history of philosophy, and methodology of science." Following the tradition of KUL's school of philosophy, the author treats "the problematics of signs as a typical boundary problem which contains several different theoretical points (...) of view, and especially the metaphysical, noetic and logical one.". (shrink)
Stigma can influence the prevention and identification of fetal alcohol spectrum disorder, a leading cause of developmental delay in North America. Understanding the effects of public health practices and policies on stigma is imperative. We reviewed social science and biomedical literatures to understand the nature of stigma in FASD and its relevance from an ethics standpoint in matters of health practices and policies. We propose a descriptive model of stigma in FASD and note current knowledge gaps; discuss the ethical implications (...) of stigma based on two distinct criteria ; and describe two cases and the concerns associated with inadvertent stigmatization by public health initiatives for FASD. We recommend further empirical and ethical analyses to examine whether public health policies and practices inadvertently stigmatize and impact the success of public health initiatives and programs for FASD. (shrink)
This book taps the best American thinkers to answer the essential American question: How do we sustain our experiment in government of, by, and for the people? Authored by an extraordinary and politically diverse roster of public officials, scholars, and educators, these chapters describe our nation's civic education problem, assess its causes, offer an agenda for reform, and explain the high stakes at risk if we fail.
In his Dialogue Concerning the Two Chief World Systems, Galileo has Salviati express his admiration for mathematics, in the context of certain historical philosophical schools:That the Pythagoreans held the science of numbers in high esteem, and that Plato himself admired the human understanding and believed it to partake of divinity simply because it understood the nature of numbers, I know very well; nor am I far from being of the same opinion.It is no accident that Aristotle is not among those (...) named here by Salviati; indeed, Aristotle’s name comes up frequently in the Dialogue, as well as that of his contemporary followers, and rarely with a positive connotation. This essay will explore the possibility that... (shrink)