Grodzinsky's theory of agrammatic sentence processing fails to account for crucial empirical facts. In contrast to his predictions, the data show that there are (1) degrees of severity and (2) problems with sentences that do not require movement, and that (3) under the right task circumstances, full-fledged syntactic trees are constructed.
Caplan & Waters's neuropsychological evidence for two types of verbal working memory rests entirely on a very restricted definition of “syntactic complexity,” one in terms of word order. This opens the possibility that the dissociation they observe relates to the differential use of word-order strategies rather than to the structure of verbal working memory.
This is an analysis of the relation of green to nineteenth century thought. The author believes that green stands for three ideas. First, He is the major nineteenth century critic of utilitarianism. Second, He is the main critic of laissez-Faire individualism. Third, He is the major critic of empiricism. Green believed that experience is identical with thought; the real world is the intelligible world. The human mind, In knowing, Establishes relations with the eternal mind. The author concludes that green is (...) both a platonist and an augustinian, Eliminating particulars, Or feelings, From philosophical importance. (staff). (shrink)
Cyclin-dependent kinase 5 has been implicated in Alzheimer's disease pathogenesis. Here, we demonstrate that overexpression of p25, an activator of cdk5, led to increased levels of BACE1 mRNA and protein in vitro and in vivo. A p25/cdk5 responsive region containing multiple sites for signal transducer and activator of transcription was identified in the BACE1 promoter. STAT3 interacts with the BACE1 promoter, and p25-overexpressing mice had elevated levels of pSTAT3 and BACE1, whereas cdk5-deficient mice had reduced levels. Furthermore, mice with a (...) targeted mutation in the STAT3 cdk5 responsive site had lower levels of BACE1. Increased BACE levels in p25 overexpressing mice correlated with enhanced amyloidogenic processing that could be reversed by a cdk5 inhibitor. These data demonstrate a pathway by which p25/cdk5 increases the amyloidogenic processing of APP through STAT3-mediated transcriptional control of BACE1 that could have implications for AD pathogenesis. (shrink)
This is an analysis of the relation of green to nineteenth century thought. the author believes that green stands for three ideas. first, he is the major nineteenth century critic of utilitarianism. second, he is the main critic of laissez-faire individualism. third, he is the major critic of empiricism. green believed that experience is identical with thought; the real world is the intelligible world. the human mind, in knowing, establishes relations with the eternal mind. the author concludes that green is (...) both a platonist and an augustinian, eliminating particulars, or feelings, from philosophical importance. (staff). (shrink)
The Database on Ethics Related Legislation and Guidelines was launched in March 2007 as the fourth database of the UNESCO Global Ethics Observatory system of databases in ethics of science and technology. The database offers a collection of legal instruments searchable by region, country, bioethical themes, legal categories and applicability to specific articles of the UNESCO Universal Declaration on Bioethics and Human Rights and International Declaration on Human Genetic Data. This paper discusses the background and rationale for the database and (...) its role as a consultative and comparative resource hub for the study of ethics related legal instruments across the world, with the purpose of informing and inspiring relevant stakeholders on the implementation of the principles contained within the UNESCO declarations on bioethics. (shrink)
[H. de Regt is ‘co-supervisor’ of the current UvT PhD project ‘Consciousness: Science Says It All?’ (drs. A. Frantzen; supervisor: prof. em. dr. A. A. Derksen). This project (in which the problem of phenomenal consciousness is approached via the work of the American pragmatist John Dewey) is absorbed in the programme Pragmatism: Living versus Paper Doubt. In order to realize the project described below he has provisionally planned (a) further collaboration with prof. dr. C.J.M. Schuyt (University of Amsterdam) to realize (...) a Pragmatism Center at Tilburg University, (b) international contacts with prof. dr. Nathan Houser & prof. dr. André De Tienne at the Peirce Project Research Center, and with dr. Timothy Lyons (Faculty of Philosophy) (all at Indiana University/Purdue University, Indianapolis, United States), he will also visit the Center for Peirce Studies at the Texas Tech University, Lubbock, where the well known Peirce scholar professor Ken Ketner hosts the complete electronic available Peirce Archives; for the establishment of a Pragmatism Center in Tilburg the support of prof. Ketner will be sought, and (c) to organize two international congresses on Peircean pragmatism and contemporary philosophy of science and mind (including proceedings)]. (shrink)
Liberalism is commonly believed, especially by its exponents, to be opposed to interference by way of enforcing value judgments or concerning itself with the individual's morality. My concern is to show that this is not so and that liberalism is all the better for this. Many elements have contributed to liberal thought as we know it today, the major elements being the liberalism of which Locke is the most celebrated exponent, which is based upon a belief in natural, human rights; (...) the liberalism of which Kant is the best known exponent, which is based on respect for persons as ends in themselves; and the liberalism of Bentham and the Mills, which is based upon utilitarian ethical theories and most especially with concern for pleasure and the reduction of pain. These different elements of liberalism have led to different emphases and different political and social arrangements, but all have involved a concern to safeguard values and to use force to that end. Today they constitute strands of thought which go to make up liberal thought as we now know it, hence it is not simply a historical fact about liberalism, but a fact about its philosophical basis, that liberalism is firmly involved in certain value and moral commitments. In the remainder of this paper I shall seek to bring this out. (shrink)
This book is an introduction to philosophy of sex. The history of philosophy of sex is depicted (from Plato to Herman Schmitz) to set up the background against which the philosophy of sex by Herman Schmitz is analyzed. This leads to the discussion of topics like masturbation, the ontology of the sexed human body, and same-sex marriage.
In this philosophy classic, which was first published in 1951, E. R. Dodds takes on the traditional view of Greek culture as a triumph of rationalism. Using the analytical tools of modern anthropology and psychology, Dodds asks, "Why should we attribute to the ancient Greeks an immunity from 'primitive' modes of thought which we do not find in any society open to our direct observation?" Praised by reviewers as "an event in modern Greek scholarship" and "a book which it would (...) be difficult to over-praise," _The Greeks and the Irrational _was Volume 25 of the Sather Classical Lectures series. (shrink)
This study aims to make for a better understanding of the term 'Aspects' in linguistic theory. Its most current application is found in studies on Slavonic languages. In the abundant literature on the contrast between the Durative (or Imperfective) Aspect and the Nondurative (or Perfective) Aspect, their occurrence has been taken to be restricted to Slavonic and some other languages, generally speaking to languages whose Verbal systems are morphologically characte.rized with regard to this opposition. The central hypothesis of transformational-generative theory (...) that a dis- tinction should be made between the deep structure and the surface structure of a language, entails the possibility for morphological systematicity to be nothing more than a manifestation of a general or even universal re- gularity expressed, for example, in the syntactic component of grammers of other languages. It will be shown in this study that the opposition between the two Aspects is present in Dutch, and as can be seen from the translated material, also in English, and that it should be described as the expression of regularities of a primarily syntactic-semantic nature. (shrink)