Since its introduction, multivariate pattern analysis, or ‘neural decoding’, has transformed the field of cognitive neuroscience. Underlying its influence is a crucial inference, which we call the decoder’s dictum: if information can be decoded from patterns of neural activity, then this provides strong evidence about what information those patterns represent. Although the dictum is a widely held and well-motivated principle in decoding research, it has received scant philosophical attention. We critically evaluate the dictum, arguing that it is false: decodability is (...) a poor guide for revealing the content of neural representations. However, we also suggest how the dictum can be improved on, in order to better justify inferences about neural representation using MVPA. 1Introduction 2A Brief Primer on Neural Decoding: Methods, Application, and Interpretation 2.1What is multivariate pattern analysis? 2.2The informational benefits of multivariate pattern analysis 3Why the Decoder’s Dictum Is False 3.1We don’t know what information is decoded 3.2The theoretical basis for the dictum 3.3Undermining the theoretical basis 4Objections and Replies 4.1Does anyone really believe the dictum? 4.2Good decoding is not enough 4.3Predicting behaviour is not enough 5Moving beyond the Dictum 6Conclusion. (shrink)

Since its introduction, multivariate pattern analysis, or ‘neural decoding’, has transformed the field of cognitive neuroscience. Underlying its influence is a crucial inference, which we call the decoder’s dictum: if information can be decoded from patterns of neural activity, then this provides strong evidence about what information those patterns represent. Although the dictum is a widely held and well-motivated principle in decoding research, it has received scant philosophical attention. We critically evaluate the dictum, arguing that it is false: decodability is (...) a poor guide for revealing the content of neural representations. However, we also suggest how the dictum can be improved on, in order to better justify inferences about neural representation using MVPA. (shrink)

ABSTRACTThe seminal work of David Marr, popularized in his classic work Vision, continues to exert a major influence on both cognitive science and philosophy. The interpretation of his work also co...

One of the classic debates in cognitive science is between nativism and empiricism about the development of psychological capacities. In principle, the debate is empirical. However, in practice nativist hypotheses have also been challenged for relying on an ill-defined, or even unscientific, notion of innateness as that which is “not learned”. Here this minimal conception of innateness is defended on four fronts. First, it is argued that the minimal conception is crucial to understanding the nativism-empiricism debate, when properly construed; Second, (...) various objections to the minimal conception—that it risks overgeneralization, lacks an account of learning, frustrates genuine explanations of psychological development, and fails to unify different notions of innateness across the sciences—are rebutted. Third, it is argued that the minimal conception avoids the shortcomings of primitivism, the prominent view that innate capacities are those that are not acquired via a psychological process in development. And fourth, the minimal conception undermines some attempts to identify innateness with a natural kind. So in short, we have little reason to reject, and good reason to accept, the minimal conception of innateness in cognitive science. (shrink)

A theoretical pillars of vision science in the information-processing tradition is that perception involves unconscious inference. The classic support for this claim is that, since retinal inputs underdetermine their distal causes, visual perception must be the conclusion of a process that starts with premises representing both the sensory input and previous knowledge about the visible world. Focus on this “argument from underdetermination” gives the impression that, if it fails, there is little reason to think that visual processing involves unconscious inference. (...) Here an alternative means of support for this pillar is proposed, based on another foundational challenge for the visual system: recognizing invariant properties of objects in the environment even though anything we encounter is never seen exactly the same way twice. Explaining how the visual system solves this invariance problem requires positing visual processes that exhibit many commonalities with inductive inference. Thus, this novel “argument from invariance” reveals one way in which visual processing clearly involves unconscious inference. (shrink)

The medium‐independence of computational descriptions has shaped common conceptions of computational explanation. So long as our goal is to explain how a system successfully carries out its computations, then we only need to describe the abstract series of operations that achieve the desired input–output mapping, however they may be implemented. It is argued that this abstract conception of computational explanation cannot be applied to so‐called real‐time computing systems, in which meeting temporal deadlines imposed by the systems with which a device (...) interfaces are constitutive of the computing tasks that a device performs. Instead, real‐time computing reveals the need for alternative conceptions of computational explanation, as well as computational implementation, that eschew medium‐independence. (shrink)

Common everyday materials such as textiles, foodstuffs, soil or skin can have complex, mutable and varied appearances. Under typical viewing conditions, most observers can visually recognize materials effortlessly, and determine many of their properties without touching them. Visual material perception raises many fascinating questions for vision researchers, neuroscientists and philosophers, yet has received little attention compared to the perception of color or shape. Here we discuss some of the challenges that material perception raises and argue that further philosophical thought should (...) be directed to how we see materials. (shrink)

This chapter situates the dispute over the metacognitive capacities of non-human animals in the context of wider debates about the phylogeny of metarepresentational abilities. This chapter clarifies the nature of the dispute, before contrasting two different accounts of the evolution of metarepresentation. One is first-person-based, claiming that it emerged initially for purposes of metacognitive monitoring and control. The other is social in nature, claiming that metarepresentation evolved initially to monitor the mental states of others. These accounts make differing predictions about (...) what we should expect to find in non-human animals: the former predicts that metacognitive capacities in creatures incapable of equivalent forms of mindreading should be found, whereas the latter predicts that they should not. The chapter elaborates and defend the latter form of account, drawing especially on what is known about decision-making and metacognition in humans. In doing so the chapter shows that so-called ‘uncertainty-monitoring’ data from monkeys can just as well be explained in non-metarepresentational affective terms, as might be predicted by the social-evolutionary account. (shrink)

Chalmers argues for the following two principles: computational sufficiency and computational explanation. In this commentary I present two criticisms of Chalmers’ argument for the principle of computational sufficiency, which states that implementing the appropriate kind of computational structure suffices for possessing mentality. First, Chalmers only establishes that a system has its mental properties in virtue of the computations it performs in the trivial sense that any physical system can be described computationally to some arbitrary level of detail; further argumentation is (...) required to show that the causal topology relevant to possessing a mind actually implements computations. Second, Chalmers' account rules out plausible cases of implementation due to its requirement of an isomorphism between the state-types of a computation and the physical system implementing the computation. (shrink)

Anderson claims that the hypothesis of massive neural reuse is inconsistent with massive mental modularity. But much depends upon how each thesis is understood. We suggest that the thesis of massive modularity presented in Carruthers (2006) is consistent with the forms of neural reuse that are actually supported by the data cited, while being inconsistent with a stronger version of reuse that Anderson seems to support.

The “hard problem” of consciousness is a challenge for explanations of the nature of our phenomenal experiences. Chalmers has claimed that physicalist solutions to the challenge are ill-suited due, in part, to the zombie argument against physicalism. Perry has suggested that the zombie argument begs the question against the physicalist, and presents no relevant threat to the view. Although seldom discussed in the literature, I show there is defensive merit to Perry’s “parry” of the zombie attack. The success of the (...) maneuver suggests a slight softening of the hard problem of consciousness for physicalists. (shrink)

Humans have the capacity for awareness of many aspects of their own mental lives—their own experiences, feelings, judgments, desires, and decisions. We can often know what it is that we see, hear, feel, judge, want, or decide. This article examines the evolutionary origins of this form of self-knowledge. Two alternatives are contrasted and compared with the available evidence. One is first-person based: self-knowledge is an adaptation designed initially for metacognitive monitoring and control. The other is third-person based: self-knowledge depends on (...) the prior evolution of a mindreading system which can then be directed toward the self. It is shown that the latter account is currently the best supported of the two. (shrink)

Questions about the nature of the relationship between language and extralinguistic cognition are old, but only recently has a new view emerged that allows for the systematic investigation of claims about linguistic structure, based on how it is understood or utilized outside of the language system. Our paper represents a case study for this interaction in the domain of event semantics. We adopt a transparency thesis about the relationship between linguistic structure and extralinguistic cognition, investigating whether different lexico-syntactic structures can (...) differentially recruit the visual causal percept. A prominent analysis of causative verbs like move suggests reference to two distinct events and a causal relationship between them, whereas non-causative verbs like push do not so refer. In our study, we present English speakers with simple scenes that either do or do not support the perception of a causal link, and manipulate (between subjects) a one-sentence instruction for the evaluation of the scene. Preliminary results suggest that competent speakers of English are more likely to judge causative constructions than non-causative constructions as true of a scene where causal features are present in the scene. Implications for a new approach to the investigation of linguistic meanings and future directions are discussed. (shrink)

Burt's argument relies on a motte-and-bailey fallacy. Burt aims to argue against the value of genetics for social science; instead she argues against certain interpretations of a specific kind of genetics tool, polygenic scores (PGSs). The limitations, previously identified by behavioural geneticists including ourselves, do not negate the value of PGSs, let alone genetics in general, for social science.

Distributional models of semantics learn word meanings from contextual co‐occurrence patterns across a large sample of natural language. Early models, such as LSA and HAL (Landauer & Dumais, 1997; Lund & Burgess, 1996), counted co‐occurrence events; later models, such as BEAGLE (Jones & Mewhort, 2007), replaced counting co‐occurrences with vector accumulation. All of these models learned from positive information only: Words that occur together within a context become related to each other. A recent class of distributional models, referred to as (...) neural embedding models, are based on a prediction process embedded in the functioning of a neural network: Such models predict words that should surround a target word in a given context (e.g., word2vec; Mikolov, Sutskever, Chen, Corrado, & Dean, 2013). An error signal derived from the prediction is used to update each word's representation via backpropagation. However, another key difference in predictive models is their use of negative information in addition to positive information to develop a semantic representation. The models use negative examples to predict words that should not surround a word in a given context. As before, an error signal derived from the prediction prompts an update of the word's representation, a procedure referred to as negative sampling. Standard uses of word2vec recommend a greater or equal ratio of negative to positive sampling. The use of negative information in developing a representation of semantic information is often thought to be intimately associated with word2vec's prediction process. We assess the role of negative information in developing a semantic representation and show that its power does not reflect the use of a prediction mechanism. Finally, we show how negative information can be efficiently integrated into classic count‐based semantic models using parameter‐free analytical transformations. (shrink)

As the usual regulatory framework did not fit well during the last Ebola outbreak, innovative thinking still needed. In the absence of an outbreak, randomised controlled trials of clinical efficacy in humans cannot be done, while during an outbreak such trials will continue to face significant practical, philosophical, and ethical challenges. This article argues that researchers should also test the safety and effectiveness of novel vaccines in wild apes by employing a pluralistic approach to evidence. There are three reasons to (...) test vaccines in wild populations of apes: i) protect apes; ii) reduce Ebola transmission from wild animals to humans; and iii) accelerate vaccine development and licensing for humans. Data obtained from studies of vaccines among wild apes and chimpanzees may even be considered sufficient for licensing new vaccines for humans. This strategy will serve to benefit both wild apes and humans. (shrink)

This volume consists of fourteen chapters selected from papers presented at the conference 'Ethics, Medicine and Health Care: An Appraisal of the Thought of H. Tristram Engelhardt, Jr.' along with a response to those chapters by Engelhardt and a Foreword by Laurence B. McCullough. The chapters direct primary attention to various aspects of Engelhardt's philosophy of medicine and bioethics as presented in The Foundations of Bioethics and Bioethics and Secular Humanism: The Search for a Common Morality. Among the topics treated (...) are the economics of health care and the medical profession, the libertarian and communitarian aspects of Engelhardt's thought, the moral status of children, abortion, the moral foundations for a health care system, feminism and clinical epistemology, and the relation between secular and religious moralities. In response to the various challenges posed by the authors, Engelhardt considers the implications of the failure of the modern philosophical project, the role of reason in ethics, and the resolution of conflict among communities that do not share the same moral vision. The book will be of interest to professionals in medicine, philosophy, theology, health policy, and law, and to graduate students in those disciplines. (shrink)

BackgroundAn increasing number of studies utilize intracranial electrophysiology in human subjects to advance basic neuroscience knowledge. However, the use of neurosurgical patients as human research subjects raises important ethical considerations, particularly regarding informed consent and undue influence, as well as subjects’ motivations for participation. Yet a thorough empirical examination of these issues in a participant population has been lacking. The present study therefore aimed to empirically investigate ethical concerns regarding informed consent and voluntariness in Parkinson’s disease patients undergoing deep brain (...) stimulator (DBS) placement who participated in an intraoperative neuroscience study.MethodsTwo semi-structured 30-minute interviews were conducted preoperatively and postoperatively via telephone. Interviews assessed participants’ motivations for participation in the parent intraoperative study, recall of information presented during the informed consent process, and participants’ postoperative reflections on the research study.ResultsTwenty-two participants (mean age = 60.9) completed preoperative interviews at a mean of 7.8 days following informed consent and a mean of 5.2 days prior to DBS surgery. Twenty participants completed postoperative interviews at a mean of 5 weeks following surgery. All participants cited altruism or advancing medical science as “very important” or “important” in their decision to participate in the study. Only 22.7% (n = 5) correctly recalled one of the two risks of the study. Correct recall of other aspects of the informed consent was poor (36.4% for study purpose; 50.0% for study protocol; 36.4% for study benefits). All correctly understood that the study would not confer a direct therapeutic benefit to them.ConclusionEven though research coordinators were properly trained and the informed consent was administered according to protocol, participants demonstrated poor retention of study information. While intraoperative studies that aim to advance neuroscience knowledge represent a unique opportunity to gain fundamental scientific knowledge, improved standards for the informed consent process can help facilitate their ethical implementation. (shrink)

Ranking systems such as The Times Higher Education’s World University Rankings and Shanghai Jiao Tong University’s Academic Rankings of World Universities simultaneously mark global status and stimulate global academic competition. As international ranking systems have become more prominent, researchers have begun to examine whether global rankings are creating increased inequality within and between universities. Using a panel Tobit regression analysis, this study assesses the extent to which markers of inter-institutional stratification and organizational segmentation predict global status among US research universities (...) as measured by position in ARWU. Findings indicate some support that both inter-institutional stratification and organizational segmentation predict global status. (shrink)

Research suggests that perceptual experience of our movements adapts together with movement control when we are the agents of our actions. Is this agency critical for perceptual and motor adaptation? We had participants view cursor feedback during elbow extension–flexion movements when they actively moved their arm, or had their arm passively moved. We probed adaptation of movement perception by having participants report the reversal point of their unseen movement. We probed adaptation of movement control by having them aim to a (...) target. Perception and control of active movement were influenced by both types of exposure, although adaptation was stronger following active exposure. Furthermore, both types of exposure led to a change in the perception of passive movements. Our findings support the notion that perception and control adapt together, and they suggest that some adaptation is due to recalibrated proprioception that arises independently of active engagement with the environment. (shrink)

In this paper I argue against the worried view that intentional properties might be epiphenomenal. In naturalizing intentionality we ought to reject both the idea that causal powers of intentional states must supervene on local microstructures, and the idea that local supervenience justifies worries about intentional epiphenomenality since our states could counterfactually lack their intentional properties and yet have the same effects. I contend that what's wrong with even the good guys (e.g. Dennett, Dretske, Allen) is that they implicitly grant (...) that causal powers supervene locally. Finally, I argue that once we see the truth of an anti-individualism which sees cognition as a fundamentally embedded activity, it becomes clear both that granting local supervenience is granting too much, and that intentional properties do work that mere neurological properties could never do. I also suggest how a transcendental argument for intentional potency might go. (shrink)

Burt's critique of using polygenic scores in social science conflates the “scientific costs” of sociogenomics with “sociopolitical and ethical” concerns. Furthermore, she paradoxically enlists recent advances in controlling for environmental confounding to argue such confounding is scientifically “intractable.” Disinterested social scientists should support ongoing efforts to improve this technology rather than obstructing progress and excusing genetically confounded research.

It has become increasingly clear that there is a vast array of microorganisms on and in the human body, known collectively as the human microbiome. Our microbiomes are extraordinarily complex, and this complexity has been linked to human health and well-being. Given the complexity and importance of our microbiomes, we struggle with how to think about them. There is a long list of competing metaphors that we use to refer to our microbiomes, including as an “organ” containing our “second genome,” (...) as a “symbiont” in the human “holobiont,” and as an ecological “community” in the human “ecosystem,” among others. Each of these makes different assumptions about the fundamental biology of the human-microbe system, with important implications for how we choose to study microbiomes, and the therapies we envision for correcting microbiome-linked disorders. We believe that it is time to move beyond metaphors, and we propose a scientifically pluralist approach that focuses on characterizing fundamental biological properties of microbiomes such as heritability, transmission mode, rates of dispersal rates, and strength of local selection. Such an approach will allow us to break out of the confines of narrow conceptual frameworks, and to guide the exploration of our complexity as chimeric beings. (shrink)

Until recently, retention of introns in mature mRNAs has been regarded as a consequence of mis‐splicing. Intron‐retaining transcripts are thought to be non‐functional because they are readily degraded by nonsense‐mediated decay. However, recent advances in next‐generation sequencing technologies have enabled the detection of numerous transcripts that retain introns. As we review herein, intron‐retaining mRNAs play an essential conserved role in normal physiology and an emergent role in diverse diseases. Intron retention should no longer be overlooked as a key mechanism that (...) independently reduces gene expression in normal biology. Exploring its contribution to the development and/or maintenance of diseases is of increasing importance. (shrink)

We examined the extent to which the perceived changes in visual imagery colorfulness impact on the affect intensity associated with ordinary autobiographical events across time. We garnered support for the hypothesis that recent events become memorial phenomena via an emotion regulation process such that positive events retained their affective pleasantness longer than negative events retained affective unpleasantness because, in part, across 2 weeks the former retained their imagery colorfulness longer than the latter events did. A similar but distinct model was (...) unsupported. We discuss the significance of imagery colorfulness and affect intensity in the context of memory for everyday autobiographical events. (shrink)

IntroductionThe value of a short life characterized by disability has been hotly debated in the literature on fetal and neonatal outcomes.MethodsWe conducted a scoping review to summarize the available empirical literature on the experiences of families in the context of trisomy 13 and 18 (T13/18) with subsequent thematic analysis of the 17 included articles.FindingsThemes constructed include (1) Pride as Resistance, (2) Negotiating Normalcy and (3) The Significance of Time.InterpretationOur thematic analysis was guided by the moral experience framework conceived by Hunt (...) and Carnevale (2011) in association with the VOICE (Views On Interdisciplinary Childhood Ethics) collaborative research group.RelevanceThis article will be of interest and value to healthcare professionals and bioethicists who support families navigating the medically and ethically complex landscape of T13/18. (shrink)

This paper explores relationships between environment and education after the Covid-19 pandemic through the lens of philosophy of education in a new key developed by Michael Peters and the Philosophy of Education Society of Australasia. The paper is collectively written by 15 authors who responded to the question: Who remembers Greta Thunberg? Their answers are classified into four main themes and corresponding sections. The first section, ‘As we bake the earth, let's try and bake it from scratch’, gathers wider philosophical (...) considerations about the intersection between environment, education, and the pandemic. The second section, ‘Bump in the road or a catalyst for structural change?’, looks more closely into issues pertaining to education. The third section, ‘If you choose to fail us, we will never forgive you’, focuses to Greta Thunberg’s messages and their responses. The last section, ‘Towards a new normal’, explores future scenarios and develops recommendations for critical emancipatory action. The concluding part brings these insights together, showing that resulting synergy between the answers offers much more then the sum of articles’ parts. With its ethos of collectivity, interconnectedness, and solidarity, philosophy of education in a new key is a crucial tool for development of post-pandemic education. (shrink)