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Summary Articles included in Developmental Biology, Misc. are those that do not focus on a topic from any other sub-category.   
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81 found
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1 — 50 / 81
  1. added 2018-12-10
    Targeting Cancer's Weaknesses : Therapeutic Strategies Suggested by the Atavistic Model.Charles H. Lineweaver, Paul C. W. Davies & Mark D. Vincent - 2014 - Bioessays 36 (9):827-835.
    In the atavistic model of cancer progression, tumor cell dedifferentiation is interpreted as a reversion to phylogenetically earlier capabilities. The more recently evolved capabilities are compromised first during cancer progression. This suggests a therapeutic strategy for targeting cancer: design challenges to cancer that can only be met by the recently evolved capabilities no longer functional in cancer cells. We describe several examples of this target‐the‐weakness strategy. Our most detailed example involves the immune system. The absence of adaptive immunity in immunosuppressed (...)
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  2. added 2018-12-09
    Visions of Eye Commensals: The Known and the Unknown About How the Microbiome Affects Eye Disease.Anthony J. St Leger & Rachel R. Caspi - 2018 - Bioessays 40 (11):1800046.
    Until recently, the ocular surface is thought by many to be sterile and devoid of living microbes. It is now becoming clear that this may not be the case. Recent and sophisticated PCR analyses have shown that microbial DNA‐based “signatures” are present within various ethnic, geographic, and contact lens wearing communities. Furthermore, using a mouse model of ocular surface disease, we have shown that the microbe, Corynebacterium mastitidis (C. mast), can stably colonize the ocular mucosa and that a causal relationship (...)
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  3. added 2018-11-26
    Mitochondria: The Red Queen Lies Within.Bram Kuijper - 2015 - Bioessays 37 (9):934-934.
  4. added 2018-11-19
    Rethinking the Role of the Nervous System: Lessons From the Hydra Holobiont.Alexander V. Klimovich & Thomas C. G. Bosch - 2018 - Bioessays 40 (9):1800060.
    Here we evaluate our current understanding of the function of the nervous system in Hydra, a non‐bilaterian animal which is among the first metazoans that contain neurons. We highlight growing evidence that the nervous system, with its rich repertoire of neuropeptides, is involved in controlling resident beneficial microbes. We also review observations that indicate that microbes affect the animal's behavior by directly interfering with neuronal receptors. These findings provide new insight into the original role of the nervous system, and suggest (...)
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  5. added 2018-11-05
    Tissue Mechanical Forces and Evolutionary Developmental Changes Act Through Space and Time to Shape Tooth Morphology and Function.Zachary T. Calamari, Jimmy Kuang‐Hsien Hu & Ophir D. Klein - 2018 - Bioessays 40 (12):1800140.
    Efforts from diverse disciplines, including evolutionary studies and biomechanical experiments, have yielded new insights into the genetic, signaling, and mechanical control of tooth formation and functions. Evidence from fossils and non‐model organisms has revealed that a common set of genes underlie tooth‐forming potential of epithelia, and changes in signaling environments subsequently result in specialized dentitions, maintenance of dental stem cells, and other phenotypic adaptations. In addition to chemical signaling, tissue forces generated through epithelial contraction, differential growth, and skeletal constraints act (...)
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  6. added 2018-10-29
    The Unpredictability of Cellular Behavior: Trivial or of Fundamental Importance to Cell Biology?M. B. Hallett - 1988 - Perspectives in Biology and Medicine 33 (1):110-119.
  7. added 2018-10-26
    Molecular and Developmental Biology.Paul Griffiths - 2002 - In Peter Machamer Michael Silberstein (ed.), The Blackwell Guide to the Philosophy of Science. Blackwell. pp. 252--271.
  8. added 2018-10-25
    Microbial Diversity in the Eukaryotic SAR Clade: Illuminating the Darkness Between Morphology and Molecular Data.Jean-David Grattepanche, Laura M. Walker, Brittany M. Ott, Daniela L. Paim Pinto, Charles F. Delwiche, Christopher E. Lane & Laura A. Katz - 2018 - Bioessays 40 (4):1700198.
    Despite their diversity and ecological importance, many areas of the SAR—Stramenopila, Alveolata, and Rhizaria—clade are poorly understood as the majority (90%) of SAR species lack molecular data and only 5% of species are from well‐sampled families. Here, we review and summarize the state of knowledge about the three major clades of SAR, describing the diversity within each clade and identifying synapomorphies when possible. We also assess the “dark area” of SAR: the morphologically described species that are missing molecular data. The (...)
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  9. added 2018-10-25
    Microbial Diversity in the Eukaryotic SAR Clade: Illuminating the Darkness Between Morphology and Molecular Data.Jean‐David Grattepanche, Laura M. Walker, Brittany M. Ott, Daniela L. Paim Pinto, Charles F. Delwiche, Christopher E. Lane & Laura A. Katz - 2018 - Bioessays 40 (4).
    Despite their diversity and ecological importance, many areas of the SAR—Stramenopila, Alveolata, and Rhizaria—clade are poorly understood as the majority of SAR species lack molecular data and only 5% of species are from well-sampled families. Here, we review and summarize the state of knowledge about the three major clades of SAR, describing the diversity within each clade and identifying synapomorphies when possible. We also assess the “dark area” of SAR: the morphologically described species that are missing molecular data. The majority (...)
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  10. added 2018-10-25
    Lehrman's Dictum: Information and Explanation in Developmental Biology.Paul E. Griffiths - 2013 - Developmental Psychobiology 55 (1):22--32.
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  11. added 2018-10-19
    Hans Drieschs Argumente Für den Vitalismus.Marcel Weber - 1999 - Philosophia Naturalis 36 (2):263-293.
    Ich rekonstruiere und kritisiere Hans Drieschs Argumentation für die Behauptung, daß biologischen Prozessen nur eine substanzdualistische Ontologie der belebten Materie (Vitalismus) gerecht werden kann. Meine Diagnose lautet, daß Drieschs Argumentation zwar logisch schlüssig ist bzw. durch leichte Modifikationen in eine logisch gültige Form gebracht werden kann, aber von empirisch unbegründeten, metaphysischen Prämissen über die Möglichkeiten eines energieumwandelnden Mechanismus ausgeht.
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  12. added 2018-10-11
    Cellular Lifespan and Senescence: A Complex Balance Between Multiple Cellular Pathways.David Dolivo, Sarah Hernandez & Tanja Dominko - 2016 - Bioessays 38 (S1):S33-S44.
  13. added 2018-10-07
    Could We Also Be Regenerative Superheroes, Like Salamanders?Alessandra Dall'Agnese & Pier Lorenzo Puri - 2016 - Bioessays 38 (9):917-926.
  14. added 2018-07-09
    How-Possibly Explanation in Biology: Lessons From Wilhelm His’s ‘Simple Experiments’ Models.Christopher Pearson - 2018 - Philosophy, Theory, and Practice in Biology 10 (4).
    A common view of how-possibly explanations in biology treats them as explanatorily incomplete. In addition to this interpretation of how-possibly explanation, I argue that there is another interpretation, one which features what I term “explanatory strategies.” This strategy-centered interpretation of how-possibly explanation centers on there being a different explanatory context within which how-possibly explanations are offered. I contend that, in conditions where this strategy context is recognized, how-possibly explanations can be understood as complete explanations. I defend this alternative interpretation by (...)
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  15. added 2018-06-27
    What is an Organism? An Immunological Answer.Thomas Pradeu - 2010 - History and Philosophy of the Life Sciences 32 (2-3):247-267.
    The question “What is an organism?”, formerly considered as essential in biology, has now been increasingly replaced by a larger question, “What is a biological individual?”. On the grounds that i) individuation is theory-dependent, and ii) physiology does not offer a theory, biologists and philosophers of biology have claimed that it is the theory of evolution by natural selection which tells us what counts as a biological individual. Here I show that one physiological field, immunology, offers a theory, which makes (...)
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  16. added 2017-08-07
    Stem Cell Lineages: Between Cell and Organism.Melinda Bonnie Fagan - 2017 - Philosophy, Theory, and Practice in Biology 9 (6).
    Ontologies of living things are increasingly grounded on the concepts and practices of current life science. Biological development is a process, undergone by living things, which begins with a single cell and (in an important class of cases) ends with formation of a multicellular organism. The process of development is thus prima facie central for ideas about biological individuality and organismality. However, recent accounts of these concepts do not engage developmental biology. This paper aims to fill the gap, proposing the (...)
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  17. added 2017-05-01
    Imitation as an Inheritance System.Nicholas Shea - 2009 - Philosophical Transactions of the Royal Society B 364:2429-2443.
    What is the evolutionary significance of the various mechanisms of imitation, emulation and social learning found in humans and other animals? This paper presents an advance in the theoretical resources for addressing that question, in the light of which standard approaches from the cultural evolution literature should be refocused. The central question is whether humans have an imitationbased inheritance system—a mechanism that has the evolutionary function of transmitting behavioural phenotypes reliably down the generations. To have the evolutionary power of an (...)
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  18. added 2017-04-20
    Recent Work in The Philosophy of Biology.Christopher J. Austin - 2017 - Analysis 77 (2):anx032.
    The biological sciences have always proven a fertile ground for philosophical analysis, one from which has grown a rich tradition stemming from Aristotle and flowering with Darwin. And although contemporary philosophy is increasingly becoming conceptually entwined with the study of the empirical sciences with the data of the latter now being regularly utilised in the establishment and defence of the frameworks of the former, a practice especially prominent in the philosophy of physics, the development of that tradition hasn’t received the (...)
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  19. added 2017-03-27
    Tell Us Your Story About You and Your Proteins.Green Linna - 2017
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  20. added 2017-01-25
    Embryos in Their Full Glory. Embryos: Color Atlas of Development . Edited by Jonathan Brad. Times Mirror International Publishers, Aylesford, Kent. 224 Pp. £49.95. ISBN 0 7234 1740 7. [REVIEW]Adam S. Wilkins - 1995 - Bioessays 17 (3):269-270.
  21. added 2017-01-16
    Eine neue Sicht der Evolution: Ist es nur der Zufall, der sie leitet?Paul Gottlob Layer - 2016 - BRIEFE Zur Orientierung Im Konflikt Mensch - Erde, Evangelische Akademie Sachsen-Anhalt E.V 121 (4):16-24.
    Nach neodarwinistischem Verständnis der Evolution entstehen neue Organismen letztlich durch rein zufällige Mutationsprozesse auf genetischer Ebene. Ihre Überlebenschancen werden dann durch die jeweilig herrschende Umwelt begünstigt oder unterdrückt. Die Evolution ist demnach nur vom reinen Zufall geleitet. Neuere Einsichten aus Entwicklungsbiologie (EvoDevo) und Epigenetik haben unsere Sicht der Evolutionsabläufe jedoch deutlich erweitert. Dabei kommt der Umwelt eine lenkende Rolle zu, der reine Zufall verliert an Bedeutung. Damit lässt sich naturwissenschaftliches Verständnis wieder besser mit herkömmlichen Schöpfungsbildern versöhnen.
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  22. added 2016-12-25
    Fixismo e evolução : epistemologia da biologia.Ana Cecília Correia Lima Tripicchio - 2005 - Dissertation, University of Campinas
    http://www.bibliotecadigital.unicamp.br/document/?code=vtls000363614.
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  23. added 2016-12-08
    The Embryological Origins of the Gene Theory.Scott F. Gilbert - 1978 - Journal of the History of Biology 11 (2):307-351.
  24. added 2016-12-04
    Aristotle on Epigenesis.Devin Henry - manuscript
    It has become somewhat of a platitude to call Aristotle the first epigenesist insofar as he thought form and structure emerged gradually from an unorganized, amorphous embryo. But modern biology now recognizes two senses of “epigenesis”. The first is this more familiar idea about the gradual emergence of form and structure, which is traditionally opposed to the idea of preformationism. But modern biologists also use “epigenesis” to emphasize the context-dependency of the process itself. Used in this sense development is not (...)
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  25. added 2016-11-18
    Evo-Devo: A Science of Dispositions.Christopher J. Austin - 2017 - European Journal for Philosophy of Science 7 (2):373-389.
    Evolutionary developmental biology represents a paradigm shift in the understanding of the ontogenesis and evolutionary progression of the denizens of the natural world. Given the empirical successes of the evo-devo framework, and its now widespread acceptance, a timely and important task for the philosophy of biology is to critically discern the ontological commitments of that framework and assess whether and to what extent our current metaphysical models are able to accommodate them. In this paper, I argue that one particular model (...)
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  26. added 2016-10-27
    A Companion to Aristotle.Georgios Anagnostopoulos (ed.) - 2008 - Wiley-Blackwell.
    _The Blackwell Companion to Aristotle_ provides in-depth studies of the main themes of Aristotle's thought, from art to zoology. The most comprehensive single volume survey of the life and work of Aristotle Comprised of 40 newly commissioned essays from leading experts Coves the full range of Aristotle's work, from his 'theoretical' inquiries into metaphysics, physics, psychology, and biology, to the practical and productive "sciences" such as ethics, politics, rhetoric, and art.
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  27. added 2016-05-30
    Art's Phases of Evolution and Heredity. [REVIEW]Frederick G. Henke - 1912 - Journal of Philosophy 9 (5):138.
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  28. added 2016-05-24
    The Ethics of Synthetic Biology: Guiding Principles for Emerging Technologies.Amy Gutmann - 2011 - Hastings Center Report 41 (4):17-22.
    The Presidential Commission for the Study of Bioethical Issues released its first report, New Directions: The Ethics of Synthetic Biology and Emerging Technologies, on December 16, 2010.1 President Barack Obama had requested this report following the announcement last year that the J. Craig Venter Institute had created the world’s first self-replicating bacterial cell with a completely synthetic genome. The Venter group’s announcement marked a significant scientific milestone in synthetic biology, an emerging field of research that aims to combine the knowledge (...)
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  29. added 2016-05-24
    Conrad H. Waddington: Towards a Theoretical Biology.Brian K. Hall & Manfred D. Laubichler - 2008 - Biological Theory 3 (3):233-237.
  30. added 2016-05-24
    In Search of New Principles of Development Biological Asymmetry and Handedness (1991). Ciba Symposium 162, Ed. Gregory R. Bock AND Joan Marsh. John Wiley. PP.iX+327. £47.40 ISBN 0 471 92961 1. [REVIEW]J. B. Gurdon - 1992 - Bioessays 14 (6):427-427.
  31. added 2016-05-24
    The Early Development of Human Embryos.Clifford Grobstein - 1985 - Journal of Medicine and Philosophy 10 (3):213-236.
    The development of the human embryo from the time of fertilization through the eighth post-fertilization week is described for medical policy purposes. During pre-implantation stages, differentiation occurs between precursors of embryonic and extra-embryonic structures. During implantation formation of a fore-hind axis begins within the inner cell mass. By the end of the eighth week, head, face, hands, and feet are suggestive as to species-recognition but not yet definitive. Data from laboratory studies of non-human mammalian embryos elucidate important aspects of human (...)
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  32. added 2016-05-24
    Der Feldbegriff in Seiner Anwendung Auf Das Problem der Zellteilung.Alex Gurwitsch & Lydia Gurwitsch - 1936 - Acta Biotheoretica 2 (2):77-92.
    The authors show that in certain isolated tissues the mitotic processes continue during at least one hour. They are very strongly stimulated by heat and also by mitogenetic radiation. In the case of the cancer cells new mitoses are promoted in considerable number. A detailed analysis of both energy factors leads to the conclusion that they effect a disturbance of the unstable constellations of the elementary particles in the cell-body. Thus a certain degree of disorganisation of its plasma seems to (...)
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  33. added 2016-05-16
    Pre‐Modern Islamic Medical Ethics and Graeco‐Islamic‐Jewish Embryology.Mohammed Ghaly - 2014 - Bioethics 28 (2):49-58.
    This article examines the, hitherto comparatively unexplored, reception of Greek embryology by medieval Muslim jurists. The article elaborates on the views attributed to Hippocrates (d. ca. 375 BC), which received attention from both Muslim physicians, such as Avicenna (d. 1037), and their Jewish peers living in the Muslim world including Ibn Jumayʽ (d. ca. 1198) and Moses Maimonides (d. 1204). The religio-ethical implications of these Graeco-Islamic-Jewish embryological views were fathomed out by the two medieval Muslim jurists Shihāb al-Dīn al-Qarāfī (d. (...)
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  34. added 2016-05-16
    Analysis of Generative Mechanisms.Björn Blom & Stefan Morén - 2011 - Journal of Critical Realism 10 (1):60-79.
    The focus of this article is the analysis of generative mechanisms, a basic concept and phenomenon within the metatheoretical perspective of critical realism. It is emphasized that research questions and methods, as well as the knowledge it is possible to attain, depend on the basic view – ontologically and epistemologically – regarding the phenomenon under scrutiny. A generative mechanism is described as a trans empirical but real existing entity, explaining why observable events occur. Mechanisms are mostly possible to grasp only (...)
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  35. added 2016-05-16
    Google Embryo for Building Quantitative Understanding of an Embryo As It Builds Itself. I. Lessons From Ganymede and Google Earth.Richard Gordon - 2009 - Biological Theory 4 (4):390-395.
    Google Earth allows us to obtain a new vision of the planet we live on, with an ability to zoom in from space to ground level detail at any point on Earth. As it is only recently that we have been able to look toward the Earth from space, we review instead the history of imaging of the Jupiter moon Ganymede, another globe, first seen by Galileo. Observations of Ganymede are mined for lessons on the importance and impact of improving (...)
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  36. added 2016-05-16
    Google Embryo for Building Quantitative Understanding of an Embryo As It Builds Itself. II. Progress Toward an Embryo Surface Microscope.Richard Gordon - 2009 - Biological Theory 4 (4):396-412.
    Embryos start out as tiny globes, on which many important events occur, including cell divisions, shape changes and changes of neighbors, waves of contraction and expansion, motion of cell sheets, extension of filopodia, shearing of cell connections, and differentiation and morphogenesis of tissues such as skin and brain. I propose to build a robotic microscope that would enable a new way to look at embryos: Google Embryo. This is akin to sending a space probe to Jupiter and its moons, sending (...)
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  37. added 2016-05-16
    Decision-Making Processes Among Contemporary ʻulamā: Islamic Embryology and the Discussion of Frozen Embryos.Thomas Eich - 2008 - In Jonathan E. Brockopp & Thomas Eich (eds.), Muslim Medical Ethics: From Theory to Practice. University of South Carolina Press.
  38. added 2016-05-16
    A Note on Metaphysics and Embryology.Alfonso Gómez-Lobo - 2007 - Theoretical Medicine and Bioethics 28 (4):331-335.
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  39. added 2016-05-16
    Beyond the Dichotomy in Vivo - in Vitro: In Silico.Pio Garcia - unknown
    From the beginnings of the biochemistry as discipline, the dichotomy between in vivo- in vitro conditions has been in the center of their methodological discussions. With the growing influence of computer simulations - sometimes called "in silico" conditions-, a new methodological problem is added to biochemistry. However, "simulation" could be seen as a core concept that is in fact used in the in vivo - in vitro dichotomy. In this sense, in silico dimension could be considered as a natural extension (...)
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  40. added 2016-05-16
    Jason Scott Robert, Embryology, Epigenesis and Evolution: Taking Development Seriously Reviewed By.Paul E. Griffiths - 2005 - Philosophy in Review 25 (3):213-215.
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  41. added 2016-05-16
    'Show Me Your Original Face Before You Were Born': The Convergence of Public Fetuses and Sacred DNA.Scott F. Gilbert & Rebecca Howes-Mischel - 2004 - History and Philosophy of the Life Sciences 26 (3/4):377 - 479.
    Embryology is an intensely visual field, and it has provided the public with images of human embryos and fetuses. The responses to these images can be extremely powerful and personal, and the images (as well as our reactions to them) are conditioned by social and political agendas. The image of the 'autonomous fetus' abstracts the fetus from the mother, the womb, and from all social contexts, thereby emphasizing 'individuality'. The image of 'sacred DNA' emphasizes DNA as the unmoved mover, the (...)
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  42. added 2016-05-16
    Commentary-Is Human Aging Still Mysterious Enough to Be Left Only to Scientists?Aubrey D. N. J. De Grey, John W. Baynes, David Berd, Christopher B. Heward, Graham Pawelec & Gregory Stock - 2002 - Bioessays 24 (7):667-676.
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  43. added 2016-05-16
    The Chicken and the Orphean Egg: On the Function of Meaning and the Meaning of Function.Claus Emmeche - 2002 - Σημιοτκή-Sign Systems Studies 1 (1):15-32.
    A central aspect of the relation between biosemiotics and biology is investigated by asking: Is a biological concept of function intrinsically related to a biosemiotic concept of sign action, and vice versa? A biological notion of function (as some process or part that serves some purpose in the context of maintenance and reproduction of the whole organism) is discussed in the light of the attempt to provide an understanding of life processes as being of a semiotic nature, i.e., constituted by (...)
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  44. added 2016-05-16
    French Embryology and the « Mechanics of Development » From 1887 to 1910: L. Chabry, Y. Delage & E. Bataillon.Jean-Louis Fischer & Julian Smith - 1984 - History and Philosophy of the Life Sciences 6 (1):25 - 39.
  45. added 2016-02-16
    Abstrakt - Affektiv - Multimodal. Zur Verarbeitung von Bewegtbildern Im Anschluss an Cassirer, Langer Und Krois.Martina Sauer - 2016 - In Lars Christian Grabbe, Patrick Rupert-Kruse & Norbert M. Schmitz (eds.), Bildkörper. Zum Verhältnis von Bildtechnologien und Embodiment. Kiel, Germany: Büchner-Verlag. pp. 46-71.
    Is it true that there is an analogy between modes of creation and such of perception? Respective to the cultural anthropological research of Ernst Cassirer, Susanne K. Langer and John M. Krois and by the analysis of a tape of the Swiss video-artist Pipilotti Rist this initial thesis of Formal Aesthetics shall be supported. - I - -/- Lässt sich die Behauptung stützen, dass zwischen Gestaltungsweisen und Wahrnehmungsweisen eine Analogie besteht? Aufbauend auf den kulturanthropologischen Forschungen von Ernst Cassirer, Susanne K. (...)
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  46. added 2016-01-11
    Human Development – Friend or Foe to Environmental Ethics?Nigel Dower - 2000 - Environmental Values 9 (1):39 - 54.
    This article is premised on the assumption that in order for us adequately to protect our environment, significant adjustments need to be made to the ways we pursue and think about development – adjustments not merely to technologies but also to life-styles. In this respect the emphasis in much recent development literature on human development is to be welcomed as a useful corrective to definitions of development in terms of economic growth, though there is still a danger of anthropocentric assumptions. (...)
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  47. added 2016-01-11
    Embryology in the 18th Century: S. Roe's Interpretation].F. Duchesneau - 1985 - History and Philosophy of the Life Sciences 7 (2).
  48. added 2015-12-31
    Phosphatidylinositol‐4‐Phosphate: The Golgi and Beyond.Maria A. De Matteis, Cathal Wilson & Giovanni D'Angelo - 2013 - Bioessays 35 (7):612-622.
  49. added 2015-12-31
    The Plant Ontology as a Tool for Comparative Plant Anatomy and Genomic Analyses.Laurel Cooper, Ramona Walls, Justin Elser, Maria A. Gandolfo, Dennis W. Stevenson, Barry Smith & Others - 2013 - Plant and Cell Physiology 54 (2):1-23..
    The Plant Ontology (PO; http://www.plantontology.org/) is a publicly-available, collaborative effort to develop and maintain a controlled, structured vocabulary (“ontology”) of terms to describe plant anatomy, morphology and the stages of plant development. The goals of the PO are to link (annotate) gene expression and phenotype data to plant structures and stages of plant development, using the data model adopted by the Gene Ontology. From its original design covering only rice, maize and Arabidopsis, the scope of the PO has been expanded (...)
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  50. added 2015-12-31
    Which Way Does the Wnt Blow? Exploring the Duality of Canonical Wnt Signaling on Cellular Aging.Nathan A. DeCarolis, Keith A. Wharton & Amelia J. Eisch - 2008 - Bioessays 30 (2):102-106.
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