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Summary

Developmental Biology is the study of organisms’ life cycles from single cell to complex reproducing and aging multi-cellular organisms. It endeavours to explain phenomena such as: cellular differentiation (e.g. neurons vs. liver cells) and cellular aging, the development of gross morphology and anatomical structures (e.g. body shape and organs -eyes and limbs-), and the development of an organism as an integrated part of an eco-system (e.g. phenotypic plasticity). The philosophically relevant points, in addition to broader philosophy of science inquiries (e.g. confirmation and explanation) are those that have to do with the ontological status of biological kinds and with inter-level relations, specifically the integration of developmental biology with evolutionary biology and to a lesser extent, with ecology. Keeping this is in mind the subcategories within Developmental Biology can be grouped into three main themes: Evolution, Ecology and Ontology.    

Evolution

(Evolutionary-Developmental Biology, Developmental Constraints and Process Structuralism)

Ecology 

(Ecological Developmental Biology, Epigenetic Inheritance, Nature vs. Nurture and Innateness) 

and 

Ontology 

(Developmental Modularity, Developmental System Theory and Process Structuralism).

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  1. Mathematical Model and Simulation of Retina and Tectum Opticum of Lower Vertebrates.U. an der Heiden & G. Roth - 1987 - Acta Biotheoretica 36 (3):179-212.
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  2. An Emerging System to Study Photosymbiosis Brain Regeneration, Chronobiology, and Behavior: The Marine Acoel Symsagittifera Roscoffensis.Enrique Arboleda, Volker Hartenstein, Pedro Martinez, Heinrich Reichert, Sonia Sen, Simon Sprecher & Xavier Bailly - forthcoming - Bioessays.
  3. Mitochondrial Heterogeneity, Metabolic Scaling and Cell Death.Juvid Aryaman, Hanne Hoitzing, Joerg P. Burgstaller, Iain G. Johnston & Nick S. Jones - 2017 - Bioessays 39 (7):1700001.
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  4. Making Sense of Life: Explaining Biological Development with Models, Metaphors, and Machines (Review).John C. Avise - 2004 - Perspectives in Biology and Medicine 47 (1):145-148.
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  5. Eugenics and Individual Phenotypic Variation: To What Extent Is Biology a Predictive Science?Evan Balaban - 1998 - Science in Context 11 (3-4):331 - 356.
    Eugenics, in whatever form it may be articulated, is based on the idea that phenotypic characteristics of particular individuals can be predicted in advance. This paper argues that biology's capacity to predict many of the characteristics exhibited by an individual, especially behavioral or cognitive attributes, will always be very limited. This stems from intrinsic limitations to the methodology for relating genotypes to phenotypes, and from the nature of developmental processes which intervene between genotypes and phenotypes. While genetic studies may generate (...)
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  6. How Did the Eukaryotes Evolve?Marcello Barbieri - 2017 - Biological Theory 12 (1):13-26.
    The fossil record shows that the stromatolites built by cyanobacteria 2 and 3 billion years ago are virtually identical to those built by their modern descendants, which is just a part of much evidence revealing that bacteria have barely changed in billions of years. They appeared very early in the history of life and have conserved their complexity ever since. The eukaryotes, however, did the opposite. They repeatedly increased the complexity of their cells and eventually broke the cellular barrier and (...)
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  7. The Cell: Locus or Object of Inquiry?William Bechtel - 2010 - Studies in History and Philosophy of Science Part C 41 (3):172-182.
    Research in many fields of biology has been extremely successful in decomposing biological mechanisms to discover their parts and operations. It often remains a significant challenge for scientists to recompose these mechanisms to understand how they function as wholes and interact with the environments around them. This is true of the eukaryotic cell. Although initially identified in nineteenth-century cell theory as the fundamental unit of organisms, researchers soon learned how to decompose it into its organelles and chemical constituents and have (...)
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  8. Manipulating Carbohydrate Metabolism to Enhance Regeneration.Caroline W. Beck - 2016 - Bioessays 38 (12):1192-1192.
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  9. Mitochondrial Outer Membrane Channels: Emerging Diversity in Transport Processes.Thomas Becker & Richard Wagner - 2018 - Bioessays 40 (7):1800013.
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  10. SMT or TOFT? How the Two Main Theories of Carcinogenesis Are Made Incompatible.Baptiste Bedessem & Stéphanie Ruphy - 2015 - Acta Biotheoretica 63 (3):257-267.
  11. SMT and TOFT Integrable After All: A Reply to Bizzarri and Cucina.Baptiste Bedessem & Stphanie Ruphy - forthcoming - Acta Biotheoretica.
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  12. Cell Death and Morphogenesis During Early Mouse Development: Are They Interconnected?Ivan Bedzhov & Magdalena Zernicka-Goetz - 2015 - Bioessays 37 (4):372-378.
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  13. Adult Neural Stem Cells: Long-Term Self-Renewal, Replenishment by the Immune System, or Both?Barbara S. Beltz, Emily L. Cockey, Jingjing Li, Jody F. Platto, Kristina A. Ramos & Jeanne L. Benton - 2015 - Bioessays 37 (5):495-501.
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  14. Travelling Waves of Cell Differentiation.M. Benmir, N. Bessonov, S. Boujena & V. Volpert - 2015 - Acta Biotheoretica 63 (4):381-395.
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  15. Germline Development in Amniotes: A Paradigm Shift in Primordial Germ Cell Specification.Federica Bertocchini & Susana M. Chuva de Sousa Lopes - 2016 - Bioessays 38 (8):791-800.
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  16. Biological Regulation: Controlling the System From Within.Leonardo Bich, Matteo Mossio, Kepa Ruiz-Mirazo & Alvaro Moreno - 2016 - Biology and Philosophy 31 (2):237-265.
    Biological regulation is what allows an organism to handle the effects of a perturbation, modulating its own constitutive dynamics in response to particular changes in internal and external conditions. With the central focus of analysis on the case of minimal living systems, we argue that regulation consists in a specific form of second-order control, exerted over the core regime of production and maintenance of the components that actually put together the organism. The main argument is that regulation requires a distinctive (...)
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  17. Love is Like Oxygen.Neil W. Blackstone - 2017 - Bioessays 39 (2):1600257.
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  18. Love is Like Oxygen.Neil W. Blackstone - 2017 - Bioessays 39 (2):1600257.
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  19. An Approach to Tumor Virus Identification.Phyllis B. Blair - 1967 - Perspectives in Biology and Medicine 11 (1):173-176.
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  20. Nanog Expression in Embryonic Stem Cells - An Ideal Model System to Dissect Enhancer Function.Steven Blinka & Sridhar Rao - 2017 - Bioessays 39 (12):1700086.
    Embryonic stem cells are derived from the preimplantation embryo and can differentiate into virtually any other cell type, which is governed by lineage specific transcriptions factors binding to cis regulatory elements to mediate changes in gene expression. The reliance on transcriptional regulation to maintain pluripotency makes ESCs a valuable model to study the role of distal CREs such as enhancers in modulating gene expression to affect cell fate decisions. This review will highlight recent advance on transcriptional enhancers, focusing on studies (...)
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  21. Symmetry-Breaking Dynamics in Development.Noah Moss Brender - 2017 - Phenomenology and the Cognitive Sciences 16 (4):585-596.
    Recognition of the plasticity of development — from gene expression to neuroplasticity — is increasingly undermining the traditional distinction between structure and function, or anatomy and behavior. At the same time, dynamic systems theory — a set of tools and concepts drawn from the physical sciences — has emerged as a way of describing what Maurice Merleau-Ponty calls the “dynamic anatomy” of the living organism. This article surveys and synthesizes dynamic systems models of development from biology, neuroscience, and psychology in (...)
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  22. What Evolvability Really Is.R. L. Brown - 2014 - British Journal for the Philosophy of Science 65 (3):549-572.
  23. The Plasticity of the Merely Human.Damon Marcel DeCoste - 2007 - Renascence 60 (1):33-52.
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  24. Glial Strategy for Metabolic Shuttling and Neuronal Function.Joachim W. Deitmer - 2000 - Bioessays 22 (8):747-752.
  25. Adaptive Responses to Genotoxic Damage: Bacterial Strategies to Prevent ‐Mutation and Cell Death.Bruce Demple - 1987 - Bioessays 6 (4):157-160.
  26. Insect Developmental Genetics – Moving Beyond Drosophila.Rob Denell - 1987 - Bioessays 6 (2):77-79.
  27. Mathematical Model and Simulation of Retina and Tectum Opticum of Lower Vertebrates.U. An der Heiden & G. Roth - 1987 - Acta Biotheoretica 36 (3):179-212.
    The processing of information within the retino-tectal visual system of amphibians is decomposed into five major operational stages, three of them taking place in the retina and two in the optic tectum. The stages in the retina involve a spatially local high-pass filtering in connection to the perception of moving objects, separation of the receptor activity into ON- and OFF-channels regarding the distinction of objects on both light and dark backgrounds, spatial integration via near excitation and far-reaching inhibition. Variation of (...)
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  28. Scienze della vita e filosofia nel Seicento e Settecento. [REVIEW]Alessandro Dini - 1987 - History and Philosophy of the Life Sciences 9 (2):327 - 332.
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  29. Embryonic Development and Induction.F. J. Dore - 1939 - Thought: Fordham University Quarterly 14 (3):510-511.
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  30. Studien Zur Theorie der Organischen Formbildung.Hans Driesch - 1937 - Acta Biotheoretica 3 (1):51-80.
    The concept of embryological “exactness” is introduced; it becomes rather complicated if a called interaction of embryological parts is in question. From the point of view of the biological mechanist “exactness” is ultimately founded upon a given material structure. The experiment is the only possible way to decide, whether the mechanistic view is right or not; mere description does not suffice here. The decision is in favor of so called vitalism. The “harmonious-equipotential system” implies “exactness”. The “genes” are not the (...)
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  31. Zur Kritik Des „Holismus”.Hans Driesch - 1936 - Acta Biotheoretica 1 (3):185-202.
  32. Embryologie au XVIII E Siècle: L'Interprétation de S. Roe. [REVIEW]François Duchesneau - 1985 - History and Philosophy of the Life Sciences 7 (2):321 - 327.
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  33. Illuminating Plant Development.Catherine M. Duckett & John C. Gray - 1995 - Bioessays 17 (2):101-103.
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  34. New Formation of Organs in Plants: The Foundation of Plant Morphogenesis.Kraft E. Von Maltzahn - 1971 - Journal of the History of Biology 4 (2):307 - 317.
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  35. Do Human Eggs Attract Spermatozoa?Michael Eisenbach & Ilan Tur-Kaspa - 1999 - Bioessays 21 (3):203-210.
  36. Ontogenetic Machinery.Lorenz Engell - 2011 - Radical Philosophy 169:10.
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  37. How Might Replicative Senescence Contribute to Human Ageing?Richard G. A. Faragher & David Kipling - 1998 - Bioessays 20 (12):985-991.
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  38. On the Logistic Law of Growth and its Empirical Verifications in Biology.Willy Feller - 1940 - Acta Biotheoretica 5 (2):51-66.
    Es wird untersucht, wie weit den empirischen Bestätigungen der logistischen Differentialgleichung als Ausdruck eines biologischen Wachstumsgesetzes tatsächliche Beweiskraft zukommt. Durch eine Reihe praktischer Ausgleichungen wurde geprüft, welche Güte der Annäherung im Durchschnitt zu erwarten ist, wenn durch eine beliebige andere dreiparametrige ScharS-förmiger Kurven ersetzt wird und ). Es zeigt sich überraschenderweise, dass sich die logistische Kurve keineswegs besonders gut dem biologischen Material anpasst, und dass letzteres auch mit ganz anderen Hypothesen vereinbar wäre. Ähnliches gilt auch von den Experimenten vonGause bewiesen (...)
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  39. Plant Morphogenesis: A Geometrical Model for the Ramification.Michel Ferré & Hervé Le Guyader - 1990 - Acta Biotheoretica 38 (3-4):181-206.
    A geometrical model is proposed that describes the emergence of a primordium at the shoot apex in Dicotyledons. It is based on recent fundamental results on plant morphogenesis, viz.:the emergence is preceded by the reorganization of the microtubules of the cortical cytoskeleton, leading to a new orientation of the synthesis of the cell wall microfibrils;the resulting global stress is related to the general orientation of the cell growth;The model sums up the continuous interactions that link the microtubules, the microfibrils and (...)
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  40. Ontogeny Recapitulates Phylogeny: A Classical Formula of Organicism in Approaches to Organic Form. Permutations in Science and Culture.Kj Fink - 1987 - Boston Studies in the Philosophy of Science 105:87-112.
  41. Development, Databases and the Internet.S. M. Frisch - 1995 - Bioessays 17:1002-1002.
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  42. [From experimental embryology to a genetics of development: from Hans Spemann to Antonio Garcia-Bellido].C. Galperin - 1999 - Revue d'Histoire des Sciences 53 (3-4):581-616.
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  43. Cognitive Modularity, Biological Modularity, and Evolvability.Claudia Lorena García - 2007 - Biological Theory 2 (1):62-73.
    I examine an argument that has recently appeared in the cognitive science literature in favor of thinking that the mind is mostly composed of Fodorian-type cognitive modules; an argument that concludes that a mind that is massively composed of classical cognitive mechanisms that are cognitively modular is more evolvable than a mind that is not cognitively modular, since a cognitive mechanism that is cognitively modular is likely to be biologically modular, and biologically modular characters are more evolvable. I argue that (...)
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  44. Christine Hertler, Morphologische Methoden in der Evolutionsforschung.M. Ghiselin - 2002 - History and Philosophy of the Life Sciences 23 (2):318-318.
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  45. Hydra as a Model for the Development of Biological Form.Alfred Gierer - 1974 - Scientific American 231 (6):44-54.
    Cells isolated from this freshwater polyp can aggregate and form a complete new animal. Experiments with the system lend support to a physico-chemical scheme for the creation of biological pattern.
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  46. Conceptions of Prenatal Development: Behavioral Embryology.Gilbert Gottlieb - 1976 - Psychological Review 83 (3):215-234.
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  47. Genetic Information: A Metaphor in Search of a Theory.Paul Edmund Griffiths - 2000 - Philosophy of Science 68 (3):394-412.
    John Maynard Smith has defended against philosophical criticism the view that developmental biology is the study of the expression of information encoded in the genes by natural selection. However, like other naturalistic concepts of information, this ‘teleosemantic’ information applies to many non-genetic factors in development. Maynard Smith also fails to show that developmental biology is concerned with teleosemantic information. Some other ways to support Maynard Smith’s conclusion are considered. It is argued that on any definition of information the view that (...)
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  48. Developmental Biology and Genetics: An Informative Overview. Genetics and Development. By JAMES H. SANG. Longman, 1984. Pp. 398. £10.50. [REVIEW]Thomas Grigliatti - 1985 - Bioessays 3 (6):278-279.
  49. Egg Distributions and the Information a Solitary Parasitoid has and Uses for its Oviposition Decisions.Lia Hemerik, Nelly van der Hoeven & Jacques J. M. van Alphen - 2002 - Acta Biotheoretica 50 (3):167-188.
    Approximately three decades ago the question was first answered whether parasitoids are able to assess the number or origin of eggs in a host for a solitary parasitoid, Leptopilina heterotoma, by fitting theoretically derived distributions to empirical ones. We extend the set of different theoretically postulated distributions of eggs among hosts by combining searching modes and abilities in assessing host quality. In the models, parasitoids search either randomly (Poisson) (1) or by vibrotaxis (Negative Binomial) (2). Parasitoids are: (a) assumed to (...)
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  50. Olson's Embryo Problem.David B. Hershenov - 2002 - Australasian Journal of Philosophy 80 (4):502-511.
1 — 50 / 1239