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  1. Evidential Criteria of Homology for Comparative Psychology.Isaac Wiegman - manuscript
    While the homology concept has taken on importance in thinking about the nature of psychological kinds, no one has shown how comparative psychological and behavioral evidence can distinguish between competing homology claims. I adapt the operational criteria of homology to accomplish this. I consider two competing homology claims that compare human anger with putative aggression systems of nonhuman animals, and demonstrate the effectiveness of these criteria in adjudicating between these claims.
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  2. Essence in the Age of Evolution: A New Theory of Natural Kinds.Christopher J. Austin - 2018 - London, UK: Routledge.
    This book offers a novel defence of a highly contested philosophical position: biological natural kind essentialism. This theory is routinely and explicitly rejected for its purported inability to be explicated in the context of contemporary biological science, and its supposed incompatibility with the process and progress of evolution by natural selection. Christopher J. Austin challenges these objections, and in conjunction with contemporary scientific advancements within the field of evolutionary-developmental biology, the book utilises a contemporary neo-Aristotelian metaphysics of "dispositional properties", or (...)
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  3. Note on the Individuation of Biological Traits.Mihnea D. I. Capraru - 2018 - Journal of Philosophy 115 (4):215-221.
    Bence Nanay has argued that we must abandon the etiological theory of teleological function because this theory explains functions and functional categories in a circular manner. Paul Griffiths argued earlier that we should retain the etiological theory and instead prevent the circularity by making etiologies independent of functional categories. Karen Neander and Alex Rosenberg reply to Nanay similarly, and argue that we should analyze functions in terms of natural selection acting not on functional categories, but merely on lineages. Nanay replies (...)
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  4. The Fine Structure of ‘Homology’.Aaron Novick - 2018 - Biology and Philosophy 33 (1-2):6.
    There is long-standing conflict between genealogical and developmental accounts of homology. This paper provides a general framework that shows that these accounts are compatible and clarifies precisely how they are related. According to this framework, understanding homology requires both an abstract genealogical account that unifies the application of the term to all types of characters used in phylogenetic systematics and locally enriched accounts that apply only to specific types of characters. The genealogical account serves this unifying role by relying on (...)
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  5. Bodily Parts in the Structure-Function Dialectic.Ingo Brigandt - 2017 - In Scott Lidgard & Lynn K. Nyhart (eds.), Biological Individuality: Integrating Scientific, Philosophical, and Historical Perspectives. Chicago: University of Chicago Press. pp. 249–274.
    Understanding the organization of an organism by individuating meaningful parts and accounting for organismal properties by studying the interaction of bodily parts is a central practice in many areas of biology. While structures are obvious bodily parts and structure and function have often been seen as antagonistic principles in the study of organismal organization, my tenet is that structures and functions are on a par. I articulate a notion of function (functions as activities), according to which functions are bodily parts (...)
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  6. Homologizing as Kinding.Catherine Kendig - 2016 - In C. Kendig (ed.), Natural Kinds and Classification in Scientific Practice. Routledge.
    Homology is a natural kind concept, but one that has been notoriously elusive to pin down. There has been sustained debate over the nature of correspondence and the units of comparison. But this continued debate over its meaning has focused on defining homology rather than on its use in practice. The aim of this chapter is to concentrate on the practices of homologizing. I define “homologizing” to be a concept-in-use. Practices of homologizing are kinds of rule following, the satisfaction of (...)
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  7. Natural Kinds and Classification in Scientific Practice.Catherine Kendig (ed.) - 2016 - Routledge.
    This edited volume of 13 new essays aims to turn past discussions of natural kinds on their head. Instead of presenting a metaphysical view of kinds based largely on an unempirical vantage point, it pursues questions of kindedness which take the use of kinds and activities of kinding in practice as significant in the articulation of them as kinds. The book brings philosophical study of current and historical episodes and case studies from various scientific disciplines to bear on natural kinds (...)
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  8. Developmental Evolution of Novel Structures – Animals.A. C. Love & D. Urban - 2016 - In R. Kliman (ed.), Encyclopedia of Evolutionary Biology. Volume 3. Academic Press. pp. 136–145.
    The origination of novel structures has long been an intriguing topic for biologists. Over the past few decades it has served as a central theme in evolutionary developmental biology. Yet, definitions of evolutionary innovation and novelty are frequently debated and there remains disagreement about what kinds of causal factors best explain the origin of qualitatively new variation in the history of life. Here we examine aspects of these debates, survey three empirical case studies, and reflect on directions for future inquiry (...)
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  9. Angry Rats and Scaredy Cats: Lessons From Competing Cognitive Homologies.Isaac Wiegman - 2016 - Biological Theory 11 (4):224-240.
    There have been several recent attempts to think about psychological kinds as homologies. Nevertheless, there are serious epistemic challenges for individuating homologous psychological kinds, or cognitive homologies. Some of these challenges are revealed when we look at competing claims of cognitive homology. This paper considers two competing homology claims that compare human anger with putative aggression systems of nonhuman animals. The competition between these hypotheses has been difficult to resolve in part because of what I call the boundary problem: boundaries (...)
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  10. Ahistorical Homology and Multiple Realizability.Sergio Balari & Guillermo Lorenzo - 2015 - Philosophical Psychology 28 (6):881-902.
    The Mind-Brain Identity Theory lived a short life as a respectable philosophical position in the late 1950s, until Hilary Putnam developed his famous argument on the multiple realizability of mental states. The argument was, and still is, taken as the definitive demonstration of the falsity of Identity Theory and the foundation on which contemporary functionalist computational cognitive science was to be grounded. In this paper, in the wake of some contemporary philosophers, we reopen the case for Identity Theory and offer (...)
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  11. Why Development Matters.Rachael L. Brown - 2015 - Biology and Philosophy 30 (6):889-899.
    Günter Wagner’s Homology, Genes, and Evolutionary Innovation is a compelling, and empirically well-supported account of the evolution of character identity and character origination which emphasizes the importance of homology and novelty as central explananda for 21st century evolutionary biology. In this essay review, I focus on the similarities and differences between the structuralist picture of evolutionary biology advocated by Wagner, and that presented by standard evolutionary theory. First, I outline the ways in which Wagner’s genetic theory of homology diverges from (...)
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  12. ChINs, Swarms, and Variational Modalities: Concepts in the Service of an Evolutionary Research Program: Günter P. Wagner: Homology, Genes, and Evolutionary Innovation. Princeton University Press, Princeton, NJ, 2014. 496 Pp, $60.00, £41.95 . ISBN 978-0-691-15646-0.Alan C. Love - 2015 - Biology and Philosophy 30 (6):873-888.
    Günter Wagner’s Homology, Genes, and Evolutionary Innovation collects and synthesizes a vast array of empirical data, theoretical models, and conceptual analysis to set out a progressive research program with a central theoretical commitment: the genetic theory of homology. This research program diverges from standard approaches in evolutionary biology, provides sharpened contours to explanations of the origin of novelty, and expands the conceptual repertoire of evolutionary developmental biology. I concentrate on four aspects of the book in this essay review: the genetic (...)
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  13. Homology and the Evolutionary Process: Reply to Haig, Love and Brown on “Homology, Genes and Evolutionary Innovation”.Günter P. Wagner - 2015 - Biology and Philosophy 30 (6):901-912.
    This paper responds to the essay reviews by David Haig, Alan Love and Rachel Brown of my recently published book “Homology, Genes and Evolutionary Innovation”. The issues addressed here relate to: the notion of classes and individuals, issues of explanatory value of adaptive and structuralist explanations in evolutionary biology, the role of homology in evolutionary theory, the limits of a pluralist stance vis a vis alternative explanations of homology, as well as the question whether and to what extend the perspective (...)
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  14. Venomous Dinosaurs and Rear-Fanged Snakes: Homology and Homoplasy Characterized. [REVIEW]Adrian Mitchell Currie - 2014 - Erkenntnis 79 (3):701-727.
    I develop an account of homology and homoplasy drawing on their use in biological inference and explanation. Biologists call on homology and homoplasy to infer character states, support adaptationist explanations, identify evolutionary novelties and hypothesize phylogenetic relationships. In these contexts, the concepts must be understood phylogenetically and kept separate: as they play divergent roles, overlap between the two ought to be avoided. I use these considerations to criticize an otherwise attractive view defended by Gould, Hall, and Ramsey & Peterson. By (...)
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  15. Homology Across Inheritance Systems.Russell Powell & Nicholas Shea - 2014 - Biology and Philosophy 29 (6):781-806.
    Recent work on inheritance systems can be divided into inclusive conceptions, according to which genetic and non-genetic inheritance are both involved in the development and transmission of nearly all animal behavioral traits, and more demanding conceptions of what it takes for non-genetic resources involved in development to qualify as a distinct inheritance system. It might be thought that, if a more stringent conception is adopted, homologies could not subsist across two distinct inheritance systems. Indeed, it is commonly assumed that homology (...)
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  16. Developmental Causation and the Problem of Homology.David A. Baum - 2013 - Philosophy, Theory, and Practice in Biology 5 (20150505).
    While it is generally agreed that the concept of homology refers to individuated traits that have been inherited from common ancestry, we still lack an adequate account of trait individuation or inheritance. Here I propose that we utilize a counterfactual criterion of causation to link each trait with a developmental-causal (DC) gene. A DC gene is made up of the genetic information (which might or might not be physically contiguous in the genome) that is needed for the production of the (...)
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  17. Convergence as Evidence.Adrian Currie - 2013 - British Journal for the Philosophy of Science 64 (4):763-786.
    The comparative method grants epistemic access to the biological past. Comparing lineages provides empirical traction on both hypotheses about particular lineages and models of trait evolution. Understanding this evidential role is important. Although philosophers have recently turned their attention to relations of descent, little work exists exploring the status of evidence from convergences. I argue that, where they exist, convergences play a central role in the confirmation of adaptive hypotheses. I focus on ‘analogous inferences’, show how such inferences ought to (...)
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  18. Homology, Female Orgasm and the Forgotten Argument of Donald Symons.Dean J. Lee - 2013 - Biology and Philosophy 28 (6):1021-1027.
    The ‘byproduct account’ of female orgasm, a subject of renewed debate since Lloyd (The case of the female orgasm, Harvard University Press, Cambridge, 2005), is universally attributed to Symons (The evolution of human sexuality, Oxford University Press, Oxford, 1979). While this is correct to the extent that he linked it to the adaptive value of male orgasm, I argue that the attribution of the theory as we understand it to Symons is based on a serious and hitherto unrecognised misinterpretation. Symons (...)
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  19. Limitations of Natural Kind Talk in the Life Sciences: Homology and Other Cases. [REVIEW]Miles MacLeod - 2013 - Biological Theory 7 (2):109-120.
    The aim of this article is to detail some reservations against the beliefs, claims, or presuppositions that current essentialist natural kind concepts (including homeostatic property cluster kinds) model grouping practices in the life sciences accurately and generally. Such concepts fit reasoning into particular preconceived epistemic and semantic patterns. The ability of these patterns to fit scientific practice is often argued in support of homeostatic property cluster accounts, yet there are reasons to think that in the life sciences kind concepts exhibit (...)
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  20. 1 C0ncept (s) 0f Homology 1.1 Common Usages of the Term Homology.Alessandro Minelli & Giuseppe Fusco - 2013 - In Kostas Kampourakis (ed.), The Philosophy of Biology: A Companion for Educators. Springer. pp. 1--289.
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  21. Homology Thinking.Marc Ereshefsky - 2012 - Biology and Philosophy 27 (3):381-400.
    This paper explores an important type of biological explanation called ‘homology thinking.’ Homology thinking explains the properties of a homologue by citing the history of a homologue. Homology thinking is significant in several ways. First, it offers more detailed explanations of biological phenomena than corresponding analogy explanations. Second, it provides an important explanation of character similarity and difference. Third, homology thinking offers a promising account of multiple realizability in biology.
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  22. Sameness in Biology.Grant Ramsey & Anne Siebels Peterson - 2012 - Philosophy of Science 79 (2):255-275.
    Homology is a biological sameness relation that is purported to hold in the face of changes in form, composition, and function. In spite of the centrality and importance of homology, there is no consensus on how we should understand this concept. The two leading views of homology, the genealogical and developmental accounts, have significant shortcomings. We propose a new account, the hierarchical-dependency account of homology, which avoids these shortcomings. Furthermore, our account provides for continuity between special, general, and serial homology.
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  23. Essay: Homology.Ingo Brigandt - 2011 - The Embryo Project Encyclopedia.
    Homology is a central concept of comparative and evolutionary biology, referring to the presence of the same bodily parts (e.g., morphological structures) in different species. The existence of homologies is explained by common ancestry, and according to modern definitions of homology, two structures in different species are homologous if they are derived from the same structure in the common ancestor. Homology has traditionally been contrasted with analogy, the presence of similar traits in different species not necessarily due to common ancestry (...)
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  24. Darwin’s Functional Reasoning and Homology.A. C. Love - 2011 - In M. Wheeler (ed.), 150 Years of Evolution: Darwin’s Impact on Contemporary Thought & Culture. SDSU Press. pp. 49–67.
    Scientists exhibit different styles in their reasoning about the natural world (e.g., experimental, historical, or statistical). These styles have been characterized, categorized, and combined in many ways throughout the history of science.
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  25. How to Compare Homology Concepts: Class Reasoning About Evolution and Morphology in Phylogenetics and Developmental Biology.Miles MacLeod - 2011 - Biological Theory 6 (2):141-153.
    Many of the current comparisons of taxic phylogenetic and biological homology in the context of morphology focus on what are seen as categorical distinctions between the two concepts. The first, it is claimed, identifies historical patterns of conservation and variation relating taxa; the second provides a causal framework for the explanation of this conservation and variation. This leads to the conclusion that the two need not be placed in conflict and are in fact compatible, having non-competing epistemic purposes or mapping (...)
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  26. Planctomycetes and Eukaryotes: A Case of Analogy Not Homology.James O. McInerney, William F. Martin, Eugene V. Koonin, John F. Allen, Michael Y. Galperin, Nick Lane, John M. Archibald & T. Martin Embley - 2011 - Bioessays 33 (11):810-817.
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  27. Relations of Homology Between Higher Cognitive Emotions and Basic Emotions.Jason A. Clark - 2010 - Biology and Philosophy 25 (1):75-94.
    In the last 10 years, several authors including Griffiths and Matthen have employed classificatory principles from biology to argue for a radical revision in the way that we individuate psychological traits. Arguing that the fundamental basis for classification of traits in biology is that of ‘homology’ (similarity due to common descent) rather than ‘analogy’, or ‘shared function’, and that psychological traits are a special case of biological traits, they maintain that psychological categories should be individuated primarily by relations of homology (...)
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  28. Functional Homology and Functional Variation in Evolutionary Cognitive Science.Claudia Lorena García - 2010 - Biological Theory 5 (2):124-135.
    Most cognitive scientists nowadays tend to think that at least some of the mind’s capacities are the product of biological evolution, yet important conceptual problems remain for all scientists in order to be able to speak coherently of mental or cognitive systems as having evolved naturally. Two of these important problems concern the articulation of adequate, interesting, and empirically useful concepts of homology and variation as applied to cognitive systems. However, systems in cognitive science are usually understood as functional systems (...)
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  29. A Modal Theory of Function.Bence Nanay - 2010 - Journal of Philosophy 107 (8):412-431.
    The function of a trait token is usually defined in terms of some properties of other (past, present, future) tokens of the same trait type. I argue that this strategy is problematic, as trait types are (at least partly) individuated by their functional properties, which would lead to circularity. In order to avoid this problem, I suggest a way to define the function of a trait token in terms of the properties of the very same trait token. To able to (...)
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  30. Pattern Cladism, Homology, and Theory-Neutrality.Christopher H. Pearson - 2010 - History and Philosophy of the Life Sciences 32 (4).
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  31. Deep Homology: A View From Systematics.Robert W. Scotland - 2010 - Bioessays 32 (5):438-449.
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  32. Homology: Homeostatic Property Cluster Kinds in Systematics and Evolution.Leandro Assis & Ingo Brigandt - 2009 - Evolutionary Biology 36:248-255.
    Taxa and homologues can in our view be construed both as kinds and as individuals. However, the conceptualization of taxa as natural kinds in the sense of homeostatic property cluster kinds has been criticized by some systematists, as it seems that even such kinds cannot evolve due to their being homeostatic. We reply by arguing that the treatment of transformational and taxic homologies, respectively, as dynamic and static aspects of the same homeostatic property cluster kind represents a good perspective for (...)
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  33. Natural Kinds in Evolution and Systematics: Metaphysical and Epistemological Considerations.Ingo Brigandt - 2009 - Acta Biotheoretica 57 (1-2):77-97.
    Despite the traditional focus on metaphysical issues in discussions of natural kinds in biology, epistemological considerations are at least as important. By revisiting the debate as to whether taxa are kinds or individuals, I argue that both accounts are metaphysically compatible, but that one or the other approach can be pragmatically preferable depending on the epistemic context. Recent objections against construing species as homeostatic property cluster kinds are also addressed. The second part of the paper broadens the perspective by considering (...)
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  34. Accounting for Vertebrate Limbs: From Owen's Homology to Novelty in Evo-Devo.Ingo Brigandt - 2009 - Philosophy, Theory, and Practice in Biology 1 (20130604):e004.
    This article reviews the recent reissuing of Richard Owen’s On the Nature of Limbs and its three novel, introductory essays. These essays make Owen’s 1849 text very accessible by discussing the historical context of his work and explaining how Owen’s ideas relate to his larger intellectual framework. In addition to the ways in which the essays point to Owen’s relevance for contemporary biology, I discuss how Owen’s unity of type theory and his homology claims about fins and limbs compare with (...)
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  35. Homology: Integrating Phylogeny and Development.Marc Ereshefsky - 2009 - Biological Theory 4 (3):225-229.
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  36. Reflections on Systematics and Phylogenetic Reconstruction.Jeffrey H. Schwartz - 2009 - Acta Biotheoretica 57 (1-2):295-305.
    I attempt to raise questions regarding elements of systematics—primarily in the realm of phylogenetic reconstruction—in order to provoke discussion on the current state of affairs in this discipline, and also evolutionary biology in general: e.g., conceptions of homology and homoplasy, hypothesis testing, the nature of and objections to Hennigian “phylogenetic systematics”, and the schism between Darwinian descendants of the “modern evolutionary synthesis” and their supposed antagonists, cladists and punctuationalists.
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  37. Editorial: Systematics, Darwinism, and the Philosophy of Science.Francisco Vergara-Silva & Rasmus Grønfeldt Winther - 2009 - Acta Biotheoretica 57 (1-2):1-3.
  38. Character Analysis in Cladistics: Abstraction, Reification, and the Search for Objectivity.Rasmus Grønfeldt Winther - 2009 - Acta Biotheoretica 57 (1-2):129-162.
    The dangers of character reification for cladistic inference are explored. The identification and analysis of characters always involves theory-laden abstraction—there is no theory-free “view from nowhere.” Given theory-ladenness, and given a real world with actual objects and processes, how can we separate robustly real biological characters from uncritically reified characters? One way to avoid reification is through the employment of objectivity criteria that give us good methods for identifying robust primary homology statements. I identify six such criteria and explore each (...)
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  39. Forever Beyond Our Grasp?: Review of P. Kyle Stanford , Exceeding Our Grasp: Science, History, and the Problem of Unconceived Alternatives.Patrick Forber - 2008 - Biology and Philosophy 23 (1):135-141.
    Does science successfully uncover the deep structure of the natural world? Or are the depths forever beyond our epistemic grasp? Since the decline of logical positivism and logical empiricism, scientific realism has become the consensus view: of course our scientific theories apprehend the deep structure of the world. What else could explain the remarkable success of science? This is the explanationist defense of scientific realism, the “ultimate argument.” Kyle Stanford starts here and, using the history of theorizing about biological inheritance (...)
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  40. CARO: The Common Anatomy Reference Ontology.Melissa Haendel, Fabian Neuhaus, David Osumi-Sutherland, Paula M. Mabee, José L. V. Mejino Jr, Chris J. Mungall & Barry Smith - 2008 - In Anatomy Ontologies for Bioinformatics: Principles and Practice. Springer. pp. 327-349.
    The Common Anatomy Reference Ontology (CARO) is being developed to facilitate interoperability between existing anatomy ontologies for different species, and will provide a template for building new anatomy ontologies. CARO has a structural axis of classification based on the top-level nodes of the Foundational Model of Anatomy. CARO will complement the developmental process sub-ontology of the GO Biological Process ontology, using it to ensure the coherent treatment of developmental stages, and to provide a common framework for the model organism communities (...)
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  41. Homology and the Hierarchy of Biological Systems.Ralf J. Sommer - 2008 - Bioessays 30 (7):653-658.
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  42. Typology Now: Homology and Developmental Constraints Explain Evolvability.Ingo Brigandt - 2007 - Biology and Philosophy 22 (5):709-725.
    By linking the concepts of homology and morphological organization to evolvability, this paper attempts to (1) bridge the gap between developmental and phylogenetic approaches to homology and to (2) show that developmental constraints and natural selection are compatible and in fact complementary. I conceive of a homologue as a unit of morphological evolvability, i.e., as a part of an organism that can exhibit heritable phenotypic variation independently of the organism’s other homologues. An account of homology therefore consists in explaining how (...)
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  43. The Importance of Homology for Biology and Philosophy.Ingo Brigandt & Paul Edmund Griffiths - 2007 - Biology and Philosophy 22 (5):633-641.
    Editors' introduction to the special issue on homology (Biology and Philosophy Vol. 22, Issue 5, 2007).
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  44. Psychological Categories as Homologies: Lessons From Ethology.Marc Ereshefsky - 2007 - Biology and Philosophy 22 (5):659-674.
    Biology and Philosophy, forthcoming 2007.
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  45. The Phenomena of Homology.Paul Edmund Griffiths - 2007 - Biology and Philosophy 22 (5):643-658.
    Philosophical discussions of biological classification have failed to recognise the central role of homology in the classification of biological parts and processes. One reason for this is a misunderstanding of the relationship between judgments of homology and the core explanatory theories of biology. The textbook characterisation of homology as identity by descent is commonly regarded as a definition. I suggest instead that it is one of several attempts to explain the phenomena of homology. Twenty years ago the ‘new experimentalist’ movement (...)
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  46. The Formation of the Theory of Homology in Biological Sciences.Karel Kleisner - 2007 - Acta Biotheoretica 55 (4):317-340.
    Homology is among the most important comparative concepts in biology. Today, the evolutionary reinterpretation of homology is usually conceived of as the most important event in the development of the concept. This paradigmatic turning point, however important for the historical explanation of life, is not of crucial importance for the development of the concept of homology itself. In the broadest sense, homology can be understood as sameness in reference to the universal guarantor so that in this sense the different concepts (...)
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  47. Functional Homology and Homology of Function: Biological Concepts and Philosophical Consequences.Alan C. Love - 2007 - Biology and Philosophy 22 (5):691-708.
    “Functional homology” appears regularly in different areas of biological research and yet it is apparently a contradiction in terms—homology concerns identity of structure regardless of form and function. I argue that despite this conceptual tension there is a legitimate conception of ‘homology of function’, which can be recovered by utilizing a distinction from pre-Darwinian physiology (use versus activity) to identify an appropriate meaning of ‘function’. This account is directly applicable to molecular developmental biology and shares a connection to the theme (...)
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  48. Defining Vision: What Homology Thinking Contributes.Mohan Matthen - 2007 - Biology and Philosophy 22 (5):675-689.
    The specialization of visual function within biological function is reason for introducing “homology thinking” into explanations of the visual system. It is argued that such specialization arises when organisms evolve by differentiation from their predecessors. Thus, it is essentially historical, and visual function should be regarded as a lineage property. The colour vision of birds and mammals do not function the same way as one another, on this account, because each is an adaptation to special needs of the visual functions (...)
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  49. A Theory of Conceptual Advance: Explaining Conceptual Change in Evolutionary, Molecular, and Evolutionary Developmental Biology.Ingo Brigandt - 2006 - Dissertation, University of Pittsburgh
    The theory of concepts advanced in the dissertation aims at accounting for a) how a concept makes successful practice possible, and b) how a scientific concept can be subject to rational change in the course of history. Traditional accounts in the philosophy of science have usually studied concepts in terms only of their reference; their concern is to establish a stability of reference in order to address the incommensurability problem. My discussion, in contrast, suggests that each scientific concept consists of (...)
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  50. Homology and Heterochrony: The Evolutionary Embryologist Gavin Rylands de Beer (1899-1972).Ingo Brigandt - 2006 - Journal of Experimental Zoology (Molecular and Developmental Evolution) 306:317–328.
    The evolutionary embryologist Gavin Rylands de Beer can be viewed as one of the forerunners of modern evolutionary developmental biology in that he posed crucial questions and proposed relevant answers about the causal relationship between ontogeny and phylogeny. In his developmental approach to the phylogenetic phenomenon of homology, he emphasized that homology of morphological structures is to be identified neither with the sameness of the underlying developmental processes nor with the homology of the genes that are in involved in the (...)
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