Interlevel Relations in Science

The question of whether all living things are really just complex physical ones, or whether instead there are biological entities or characteristics that cannot be fully characterized in physical terms, has historical roots buried centuries deep. Carl Hempel considers this question as an empirical one for modern science to address. Hempel’s concern is not with the answer to the question, but rather with the methods by which it may be evaluated. He considers the position of those he calls “mechanists,” that (...) all living things and their biological characteristics are nothing more than complex physical systems, as equivalent to the view that in some significant sense all accurate biological theories are implied by physical ones. In so doing, Hempel seeks to draw conclusions regarding the unity of science more broadly. This paper argues that Hempel’s account, though perhaps succeeding in a crucial first step, fails on numerous points afterwards. Using the morals that may be draw from these failures, I suggest rough outlines of some alternative accounts of intertheoretic reduction. (shrink)

The discovery that some B vitamins are constituents of respiratory coenzymes led to the development of an interfield theory of the kind discussed by Darden and Maull. In this paper it is shown that the development of a useful interfield connection was made possible by two reconceptualizations: a reconceptualization that united two then-distinct fields giving rise to the concept of vitamins as dietary substances; and another reconceptualization that united two approaches to respiratory metabolism producing the idea that coenzymes are transport (...) vehicles. (shrink)

The interactivist model has explored a number of consequences of process metaphysics. These include reversals of some fundamental metaphysical assumptions dominant since the ancient Greeks, and multiple further consequences throughout the metaphysics of the world, minds, and persons. This article surveys some of these consequences, ranging from issues regarding entities and supervenience to the emergence of normative phenomena such as representation, rationality, persons, and ethics.

Instances of explanatory reduction are often advocated on metaphysical grounds; given that the only real things in the world are subatomic particles and their interaction, we have to try to explain everything in terms of the laws of physics. In this paper, we show that explanatory reduction cannot be defended on metaphysical grounds. Nevertheless, indispensability arguments for reductive explanations can be developed, taking into account actual scientific practice and the role of epistemic interests. Reductive explanations might be indispensable to address (...) some epistemic interest answering a specific explanation-seeking question in the most accurate, adequate and efficient way. Just like explanatory pluraliste often advocate the indispensability of higher levels of explanation pointing at the pragmatic value of the explanatory information obtained on these higher levels, we argue that explanatory reduction—traditionally understood as the contender of pluralism—can be defended in a similar way. The pragmatic value reductionist, lower level explanations might have in the biomédical sciences and the social sciences is illustrated by some case studies. (shrink)

This introduction to the special section on integration in biology provides an overview of the different contributions. In addition to motivating the philosophical significance of analyzing integration and interdisciplinary research, I lay out common themes and novel insights found among the special section contributions, and indicate how they exhibit current trends in the philosophical study of integration. One upshot of the contributed papers is that there are different aspects to and kinds of integration, so that rather than attempting to offer (...) a universal construal of what integrations is, philosophers have to analyze in concrete cases in what respects particular aspects of scientific theorizing and/or practice are ‘integrative’ and how this instance of integration works and was achieved. (shrink)

In this paper I respond to Wim van der Steen''s arguments against the supposed current overemphasis on norms ofcoherence andinterdisciplinary integration in biology. On the normative level, I argue that these aremiddle-range norms which, although they may be misapplied in short-term attempts to solve (temporarily?) intractable problems, play a guiding role in the longer-term treatment of biological problems. This stance is supported by a case study of apartial success story, the development of the one gene — one enzyme hypothesis. As (...) that case shows, thegoal of coherent interdisciplinary integration not only provides guidance for research, but also provides the standard for recognizingfailed integrations of the sort that van der Steen criticizes. (shrink)

In a recent volume of this journal Saatsi [Saatsi, J. . Reconsidering the Fresnel–Maxwell theory shift: How the realist can have her cake and EAT it too. Studies in History and Philosophy of Science, 36, 509–536.] suggests that we adopt an approach where we explain phenomena reductively, by properties that are described via their nomological roles. These properties are conceived of as higher-order multiply realisable properties. Such properties are however not causally efficacious independent of their causal basis. Therefore Saatsi has (...) left it open what kind of explanatory work these properties could possibly do.Keywords: Realism; Multi realisability; Structuralism; Semirealism; Eclectic realism; Higher-order propertiess. (shrink)

In another paper, one of us argued that emergence and reduction are compatible, and presented four examples illustrating both. The main purpose of this paper is to develop this position for the example of phase transitions. We take it that emergence involves behaviour that is novel compared with what is expected: often, what is expected from a theory of the system's microscopic constituents. We take reduction as deduction, aided by appropriate definitions. Then the main idea of our reconciliation of emergence (...) and reduction is that one makes the deduction after taking a limit of an appropriate parameter $N$. Thus our first main claim will be that in some situations, one can deduce a novel behaviour, by taking a limit $N\to\infty$. Our main illustration of this will be Lee-Yang theory. But on the other hand, this does not show that the $N=\infty$ limit is physically real. For our second main claim will be that in such situations, there is a logically weaker, yet still vivid, novel behaviour that occurs before the limit, i.e. for finite $N$. And it is this weaker behaviour which is physically real. Our main illustration of this will be the renormalization group description of cross-over phenomena. (shrink)

I characterize a notion of causal agency that is the causitive component of many transitive verbs. The agency of what I call substantial causes relates objects physically to systems with which they interact. Such agent causation does not reduce to conditionship relations, nor does it cease to play a role in scientific discourse. I argue, contrary to regularity theories, that causal claims do not in general depend for their sense on generalities nor do they entail the existence of laws. Clarification (...) of the relationships among substantial causes, causal processes, and explanatory conditions separates the analysis of causal connection from that of nomological connection. This clarification is then applied to a variety of issues in the analysis of causality. (shrink)

The central current of ideas in modern philosophy - through Hume, Kant and Hegel, to the present - can be understood as a reaction to the percieved threat of disorder. Against this background, the author argues for acceptance of a metaphysics of disorder, and outlines a number of important philosophical consequences of such an acceptance. When appropriately constrained by empiricist concern, such a metaphysics allows us to make sense of ourselves as as knowers who must make do in a world (...) of complexity and uncertainty. We make do by learning to export knowledge, gained where we can get it, to the many situations where knowledge eludes us. An account of causal and idealizational reasoning in science, which has much in common with the recent work of Nancy Cartwright, is developed to exemplify the main argument. The author's philosophical position is contrasted with that of recent post modernists, notably Richard Rorty. (shrink)

Reference to mechanisms is virtually ubiquitous in science and its philosophy. Yet, the concept of a mechanism remains largely unanalyzed; So too for its possible applications in thinking about scientific explanation, experimental practice, and theory structure. This dissertation investigates these issues in the context of contemporary neurobiology. ;The theories of neurobiology are hierarchically organized descriptions of mechanisms that explain functions. Mechanisms are the coordinated activities of entities by virtue of which that function is performed. Since the activities composing mechanisms are (...) often susceptible to mechanical redescription themselves, theories in neurobiology have a characteristic hierarchical structure. The activities of entities at one level are the sub-activities of those at a higher level. ;This hierarchy reveals a fundamental symmetry of functional and mechanical descriptions. Functions are privileged activities of entities; they are privileged because they constitute a stage in some higher-level mechanism. The privileged activities of entities, in turn, are explained by detailing the stages of activity in the lower-level mechanism. Functional and mechanical descriptions are different tools for situating activities, properties, and entities into a hierarchy of activities. They are not competing kinds of description. Experimental techniques for testing such descriptions reflect this symmetry. ;Philosophical discussions of inter-level explanatory relationships have traditionally been framed by reference to inter-theoretic reduction models. The representational strictures of first order predicate calculus and the epistemological strictures logical empiricism combine in this reduction model to focus attention upon issues of identity and deriveability; these are entirely peripheral to the explanatory aims of mechanical explanation. Mechanical explanation is causal. Derivational models of explanation do not adequately reflect the importance of activities in rendering phenomena intelligible. ;Activities are kinds of change. "Bonding," "diffusing," "transcribing," "opening," and "attracting" all describe different kinds of transformation. Salmon's modified process theory is helpful in understanding the role of entities and properties in causal interactions; but it ultimately makes no room for kinds of change in the explanatory cupboard. We make change intelligible by identifying and characterizing its different kinds and relating these to activities that are taken to be fundamental for a science at a time. (shrink)