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  1. LRRC8 Proteins Share a Common Ancestor with Pannexins, and May Form Hexameric Channels Involved in Cell‐Cell Communication.Federico Abascal & Rafael Zardoya - 2012 - Bioessays 34 (7):551-560.
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  2. A Plausible Function of the Prion Protein: Conjectures and a Hypothesis.Yousef H. Abdulla - 2001 - Bioessays 23 (5):456-462.
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  3. Molecular Biology and its Recent Historiography: A Transnational Quest for the 'Big Picture'.P. Abir-Am - 2006 - History of Science 44 (1):95-118.
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  4. Themes, Genres and Orders of Legitimation in the Consolidation of New Scientific Disciplines: Deconstructing the Historiography of Molecular Biology.Pninn Abir-Am - 1985 - History of Science 23 (1):73-117.
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  5. Quality Control in Databanks for Molecular Biology.E. E. Abola, A. Bairoch, W. C. Barker, S. Beck, H. da BensonBerman, G. Cameron, C. Cantor, S. Doubet & T. J. P. Hubbard - 2000 - Bioessays 22 (11):1024-1034.
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  6. Are Viruses a Source of New Protein Folds for Organisms?–Virosphere Structure Space and Evolution.Aare Abroi & Julian Gough - 2011 - Bioessays 33 (8):626-635.
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  7. The Genetic Control of Tissue Polarity in Drosophila.Paul N. Adler - 1992 - Bioessays 14 (11):735-741.
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  8. To Err and Win a Nobel Prize: Paul Boyer, ATP Synthase and the Emergence of Bioenergetics. [REVIEW]Douglas Allchin - 2002 - Journal of the History of Biology 35 (1):149 - 172.
    Paul Boyer shared a Nobel Prize in 1997 for his work on the mechanism of ATP synthase. His earlier work, though (which contributed indirectly to his triumph), included major errors, both experimental and theoretical. Two benchmark cases offer insight into how scientists err and how they deal with error. Boyer's work also parallels and illustrates the emergence of bioenergetics in the second half of the twentieth century, rivaling achievements in evolution and molecular biology.
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  9. Book Review: Essential Cell Biology Volume 1: Cell Structure and Volume 2: Cell Function, A Practical Approach. [REVIEW]Linda Amos - 2004 - Bioessays 26 (11):1255-1256.
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  10. Reduction in the Biomedical Sciences.Holly Andersen - 2016 - In Miriam Solomon, Jeremy Simon & Harold Kincaid (eds.), Routledge Companion to Philosophy of Medicine. Routledge.
    This chapter discusses several kinds of reduction that are often found in the biomedical sciences, in contrast to reduction in fields such as physics. This includes reduction as a methodological assumption for how to investigate phenomena like complex diseases, and reduction as a conceptual tool for relating distinct models of the same phenomenon. The case of Parkinson’s disease illustrates a wide variety of ways in which reductionism is an important tool in medicine.
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  11. Cancer: The Evolved Consequence of a Destabilized Genome.Garth R. Anderson, Daniel L. Stoler & Bruce M. Brenner - 2001 - Bioessays 23 (11):1037-1046.
  12. Advances in Molecular Biology of Hibernation in Mammals.Matthew T. Andrews - 2007 - Bioessays 29 (5):431-440.
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  13. A Molecular Signature for the “Master” Heart Cell.Roman Anton, Michael Kühl & Petra Pandur - 2007 - Bioessays 29 (5):422-426.
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  14. Revamping Molecular Biology for the Twentieth First Century, or Putting Back the Theoretical Horse Ahead of the Technological Cart.Armando Anzaldo - 2010 - Ludus Vitalis 18:267-270.
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  15. Back to the Future: Aristotle and Molecular Biology.Armando Aranda Anzaldo - 2007 - Ludus Vitalis 15 (28):195-198.
    The Aristotelian axiom that function follows form was beautifully instantiated in molecular biology by the discovery of DNA’s structure that immediately suggested how DNA might work as depository and vehicle for genetic information. However, later on molecular biology became infatuated with the gene that became the center of the universe. This gene-centered viewpoint is an obstacle for the emerging field of evo-devo aiming at finding the causal connections between evolution and biological development. Here it is argued that molecular biology must (...)
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  16. Molecular Biology of T‐Cell‐Derived Lymphokines: A Model System for Proliferation and Differentiation of Hemopoietic Cells.K. Arai, T. Yokota, A. Miyajima, N. Arai & F. Lee - 1986 - Bioessays 5 (4):166-171.
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  17. Revamping Molecular Biology for the Twentieth First Century, or Putting Back the Theoretical Horse Ahead of the Technological Cart.Armando Aranda-Anzaldo - 2010 - Ludus Vitalis 18 (33):267-270.
    Molecular biology is a relatively new and very successful branch of science but currently it faces challenges posed by very complex issues that cannot be addressed by a traditional reductionist approach. However, despite its origins in the providential shift of some theoretical physicists to biology, currently molecular biology is immersed in a blind trend in which high-throughput technology, able to generate trillions of data, is becoming the leading edge of a discipline that has traded rational and critical thinking for computer (...)
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  18. A Ca2+‐Binding Protein with Numerous Roles and Uses: Parvalbumin in Molecular Biology and Physiology.Syed Hasan Arif - 2009 - Bioessays 31 (4):410-421.
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  19. Four Principles of Evolutionary Pragmatics in Jacob's Philosophy of Modern Biology.Stefan Artmann - 2004 - Axiomathes 14 (4):381-395.
    The French molecular biologist François Jacob outlined a theory of evolution as tinkering. From a methodological point of view, his approach can be seen as a biologic specification of the relation between laws, describing coherently the dynamics of a system, and contingent boundary conditions on this dynamics. From a semiotic perspective, tinkering is a pragmatic concept well-known from the information-theoretic anthropology of Claude Lévi-Strauss. In idealized contrast to an engineer, the tinkerer has to accept the concrete restrictions on his material (...)
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  20. Molecular Basis of Antigenic Variation in African Trypanosomes.Frank Ashall - 1986 - Bioessays 4 (5):201-204.
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  21. Scientific Convergence in the Birth of Molecular Biology.Sunny Y. Auyang - unknown
    “I myself was forced to call myself a molecular biologist because when inquiring clergymen asked me what I did, I got tired of explaining that I was a mixture of crystallographer, biophysicist, biochemist, and geneticist.” Thus explained Francis Crick, who with James Watson discovered in 1953 the double helical structure of DNA, the genetic material..
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  22. Biological Evolution: Recent Advances Through Molecular Studies.Francisco J. Ayala - 1979 - In Vittorio Mathieu & Paolo Rossi (eds.), Scientia. Scientia Verlag. pp. 185.
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  23. Filling in the Mechanistic Details: Two-Variable Experiments as Tests for Constitutive Relevance. [REVIEW]Tudor Baetu - 2012 - European Journal for Philosophy of Science 2 (3):337-353.
    This paper provides an account of the experimental conditions required for establishing whether correlating or causally relevant factors are constitutive components of a mechanism connecting input (start) and output (finish) conditions. I argue that two-variable experiments, where both the initial conditions and a component postulated by the mechanism are simultaneously manipulated on an independent basis, are usually required in order to differentiate between correlating or causally relevant factors and constitutively relevant ones. Based on a typical research project molecular biology, a (...)
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  24. A Defense of Syntax-Based Gene Concepts in Postgenomics: Genes as Modular Subroutines in the Master Genomic Program.Tudor M. Baetu - 2011 - Philosophy of Science 78 (5):712-723.
    The purpose of this article is to update and defend syntax-based gene concepts. I show how syntax-based concepts can and have been extended to accommodate complex cases of processing and gene expression regulation. In response to difficult cases and causal parity objections, I argue that a syntax-based approach fleshes out a deflationary concept defining genes as genomic sequences and organizational features of the genome contributing to a phenotype. These organizational features are an important part of accepted molecular explanations, provide the (...)
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  25. Study and Simulation of Reaction–Diffusion Systems Affected by Interacting Signaling Pathways.Majid Bani-Yaghoub & David E. Amundsen - 2008 - Acta Biotheoretica 56 (4):315-328.
    Possible effects of interaction (cross-talk) between signaling pathways is studied in a system of Reaction–Diffusion (RD) equations. Furthermore, the relevance of spontaneous neurite symmetry breaking and Turing instability has been examined through numerical simulations. The interaction between Retinoic Acid (RA) and Notch signaling pathways is considered as a perturbation to RD system of axon-forming potential for N2a neuroblastoma cells. The present work suggests that large increases to the level of RA–Notch interaction can possibly have substantial impacts on neurite outgrowth and (...)
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  26. The More the Merrier: The Pannexin Family Just Got a New Branch (Comment on DOI 10.1002/Bies. 201100173).Ancha Baranova - 2012 - Bioessays 34 (7):530-531.
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  27. The Organic Codes: An Introduction to Semantic Biology.Marcello Barbieri - 2003 - Cambridge University Press.
    The genetic code appeared on Earth with the first cells. The codes of cultural evolution arrived almost four billion years later. These are the only codes that are recognized by modern biology. In this book, however, Marcello Barbieri explains that there are many more organic codes in nature, and their appearance not only took place throughout the history of life but marked the major steps of that history. A code establishes a correspondence between two independent 'worlds', and the codemaker is (...)
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  28. A “Chromosomic” Recombination Theory for Multiplicity Reactivation in Phages.Nils Aall Barricelli - 1956 - Acta Biotheoretica 11 (3-4):107-120.
    With the assumption of inactivation of small traits in bacteriophages “chromosomes” by ultraviolet irradiation the probability of multiplicity reactivation of irradiated phages is calculated. The result appears to be in agreement with the experimental results ofDulbecco.In the mathematical treatment of the problem a distinction is made between ordinary genes, with probability of inactivation negligible relative to the probability of inactivation of the whole phage, and a few vulnerable centers or genes whose probability of inactivation is not negligible. The hypothesis of (...)
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  29. Biochemical Kinds.J. Bartol - 2014 - British Journal for the Philosophy of Science (2):axu046.
    Chemical kinds (e.g. gold) are generally treated as having timelessly fixed identities. Biological kinds (e.g. goldfinches) are generally treated as evolved and/or evolving entities. So what kind of kind is a biochemical kind? This paper defends the thesis that biochemical molecules are clustered chemical kinds, some of which–namely, evolutionarily conserved units–are also biological kinds.On this thesis, a number of difficulties that have recently occupied philosophers concerned with proteins and kinds are shown to be resolved or dissolved.
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  30. What is so Special About Smell? Olfaction as a Model System in Neurobiology.Ann-Sophie Barwich - 2015 - Postgraduate Medical Journal 92:27-33.
    Neurobiology studies mechanisms of cell signalling. A key question is how cells recognise specific signals. In this context, olfaction has become an important experimental system over the past 25 years. The olfactory system responds to an array of structurally diverse stimuli. The discovery of the olfactory receptors (ORs), recognising these stimuli, established the olfactory pathway as part of a greater group of signalling mechanisms mediated by G-protein-coupled receptors (GPCRs). GPCRs are the largest protein family in the mammalian genome and involved (...)
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  31. Engineering Novel Proteins with Orthogonal tRNA: Artificial Causes That Make a Difference.Janella Baxter - manuscript
    Model organisms, the use of green fluorescent proteins, and orthogonal transfer RNA are examples of artificial causes being used in biology. Recent work characterizing the research interests of biologists in terms of a common set of values has ruled out artificial causes as biologically interesting. For instance, Kenneth Waters argues that biologists are primarily interested in causes that actually obtain. Similarly, Marcel Weber argues that biologists are primarily concerned with biologically normal interventions. Both views express a widely received attitude about (...)
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  32. Using Computer Algebra to Determine Rate Constants in Biochemistry.M. Bayram, J. P. Bennett & M. C. Dewar - 1993 - Acta Biotheoretica 41 (1-2):53-62.
    In earlier work we have described how computer algebra may be used to derive composite rate laws for complete systems of equations, using the mathematical technique of Gröbner Bases (Bennett, Davenport and Sauro, 1988). Such composite rate laws may then be fitted to experimental data to yield estimates of kinetic parameters.Recently we have been investigating the practical application of this methodology to the estimation of kinetic parameters for the closed two enzyme system of aspartate aminotransferase (AAT) and malate dehydrogenase (MDH) (...)
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  33. Zyxin: Zinc Fingers at Sites of Cell Adhesion.Mary C. Beckerle - 1997 - Bioessays 19 (11):949-957.
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  34. Philosophical Aspects of Molecular Biology.David Berlinski - 1972 - Journal of Philosophy 69 (12):319.
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  35. Protein Structure in a Nutshell.Philip C. Biggin - 2001 - Bioessays 23 (7):669-669.
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  36. Software Club: Software for Molecular Biology. IV. Power Where It is Needed: Workstations and Networks.Martin J. Bishop - 1985 - Bioessays 2 (5):218-221.
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  37. Software Club: Software for Molecular Biology. II. Restriction Mapping and DNA Sequencing Programs.Martin J. Bishop - 1984 - Bioessays 1 (2):75-77.
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  38. Where the Truth Lies: Franz Moewus and the Origins of Molecular Biology. [REVIEW]David Bloor - 1993 - British Journal for the History of Science 26 (2):260-263.
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  39. Mechanistic Explanations and Models in Molecular Systems Biology.Fred C. Boogerd, Frank J. Bruggeman & Robert C. Richardson - 2013 - Foundations of Science 18 (4):725-744.
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  40. Linus Pauling : Molecular Disease and the Oorigins [Sic] of Molecular Biology.Francisco Javier Serrano Bosquet - 2009 - In González Recio & José Luis (eds.), Philosophical Essays on Physics and Biology. G. Olms.
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  41. Molecular Biology of the Neuron By RW Davis, BJ Morris (Eds).D. A. Brown - 1999 - Bioessays 21:361-361.
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  42. Amphibian Metamorphosis. From Morphology to Molecular Biology.Donald D. Brown - 2000 - Bioessays 22 (8):775-775.
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  43. Ancient DNA: Using Molecular Biology to Explore the Past.Terence A. Brown & Keri A. Brown - 1994 - Bioessays 16 (10):719-726.
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  44. "The Tools of the Discipline: Biochemists and Molecular Biologists": A Comment.Richard M. Burian - 1996 - Journal of the History of Biology 29 (3):451 - 462.
    This last result leads, rather naturally, to some concluding observations and a series of questions for further investigation. These case studies show that in all of the sites examined, the institutionalization of molecular biology as a “discipline” was primarily driven by the need to separate groups of practitioners with divergent but overlapping interests within the local context. Thus molecular biology was contingently separated from agricultural or medical biochemistry, virology, work on the physiology of nucleic acids, and so forth for contingent (...)
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  45. Scientists’ Use of Diagrams in Developing Mechanistic Explanations: A Case Study From Chronobiology.Daniel C. Burnston, Benjamin Sheredos, Adele Abrahamsen & William Bechtel - 2014 - Pragmatics and Cognition 22 (2):224-243.
  46. RNA Editing: Exploring One Mode with Apolipoprotein B mRNA.Lawrence Chan - 1993 - Bioessays 15 (1):33-41.
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  47. Cell Sociology and the Problem of Automation in the Development of Pluricellular Animals.Rosine Chandebois - 1980 - Acta Biotheoretica 29 (1):1-35.
    The principles of automation (automatism and programming) in the unfolding of spatio-temporal patterns during animal development are deduced from experimental data reconsidered from the point of view of cell sociology. The developmental programme in the egg is not part of the genetic information but a part of the cytoplasmic information. Throughout development cells store extra-cellular information released by their neighbours in the form of cytoplasmic information. Successive determinations cannot be considered as successive reprogrammings of cells: each one consists of a (...)
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  48. Cell Sociology and the Problem of Position Effect: Pattern Formation, Origin and Role of Gradients.Rosine Chandebois - 1977 - Acta Biotheoretica 26 (4):203-238.
    The control of pattern formation and the significance of gradients is reconsidered on the basis of the concept of cell sociology (which takes into account continuous exchange of information between cells and the possibility of autonomous progression in differentiation). Not all traits of a pattern are imposed by a single prepattern, which would be an organized molecular framework or a gradient. Patterns are unfolded in steps; these are readjustments of a cell population to intrinsic and extrinsic changes in cell activities. (...)
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  49. Cell Sociology: A Way of Reconsidering the Current Concepts of Morphogenesis.Rosine Chandebois - 1976 - Acta Biotheoretica 25 (2-3):71-102.
    Research in the field of planarian regeneration on the one hand, and a general survey of embryology on the other, throw doubt upon the reality of supra-cellular controls, which are still at the basis of all modern concepts of morphogenesis. The necessity of referring to such controls, which have never been convincingly demonstrated, is probably due to the fact that two aspects of cell behaviour have been underestimated: 1) the capacity of cells to change their individualities for a time independently (...)
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  50. Hormones, Second Messengers and the Reversible Phosphorylation of Proteins: An Overview.Philip Cohen - 1985 - Bioessays 2 (2):63-68.
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