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  1. “The Sleeping Beauty of the Brain”: Memory, MIT, Montreal, and the Origins of Neuroscience.Yvan Prkachin - 2021 - Isis 112 (1):22-44.
  2. Introduction: Evidence, Expertise and Argumentation in Evidence-Based Medicine.Fabrizio Macagno & Carlo Martini - 2021 - Topoi 40 (2):295-298.
    [1st paragraph] A philosophical discussion on evidence-based medicine (EBM) can be probably perceived almost as an oxymoron. How can “the process of systematically finding, appraising, and using contemporaneous research findings as the basis for clinical decisions” (Jenicek 2012: 23) be compatible with the critical and systematic examination of fundamental problems such as the nature of being, reality, thinking, values and perception? How can a scientific field focused mainly on the search and evaluation of evidence and aimed at solid quantifications of (...)
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  3. Prevention of Disease and the Absent Body: A Phenomenological Approach to Periodontitis.Dylan Rakhra & Māra Grīnfelde - forthcoming - Journal of Medicine and Philosophy.
    A large part of contemporary phenomenology of medicine has been devoted to accounts of health and illness, arguing that they contribute to the improvement of healthcare. Less focus has been paid to the issue of prevention of disease and the associated difficulty of adhering to health-promoting behaviours, which is arguably of equal importance. This article offers a phenomenological account of this disease prevention, focusing on how we – as embodied beings – engage with health-promoting behaviours. It specifically considers how we (...)
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  4. Made to Measure: The Ethics of Routine Measurement for Healthcare Improvement.Polly Mitchell, Alan Cribb & Vikki Entwistle - 2021 - Health Care Analysis 29 (1):39-58.
    This paper analyses the ethics of routine measurement for healthcare improvement. Routine measurement is an increasingly central part of healthcare system design and is taken to be necessary for successful healthcare improvement efforts. It is widely recognised that the effectiveness of routine measurement in bringing about improvement is limited—it often produces only modest effects or fails to generate anticipated improvements at all. We seek to show that these concerns do not exhaust the ethics of routine measurement. Even if routine measurement (...)
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  5. Defining medical humanism beyond empathy.Juliette Ferry-Danini - 2020 - Archives de Philosophie 4 (84).
    Empathy is often described as a virtue which that could help in making medicine more humanistic. This paper argues that there are two limits to this thesis. First, it is unclear whether a lack of empathy can be attributed to the biomedical education. Second, empathy itself is not without issues, and another concept, compassion, can be put forward instead. Humanism based on compassion is more minimalist, but integrated with an approach focused on health systems, it makes humanism more tangible and (...)
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  6. Numbers, Prognosis, and Healing: Galen on Medical Theory.Glen Cooper - 2004 - Journal of the Washington Academy of Sciences 90 (2):45-60.
  7. What Is New About the Exposome? Exploring Scientific Change in Contemporary Epidemiology.Stefano Canali - 2020 - International Journal of Environmental Research and Public Health 2879 (17).
    In this commentary, I discuss the scientific changes brought by the exposome, asking what is new about this approach and line of research. I place the exposome in a historical perspective, by analyzing the conditions under which the exposome has been conceived, developed and established in the context of contemporary epidemiological research. I argue that the exposome has been developed by transferring approaches, methods and conceptualizations from other lines of research in the life and health sciences. I thus discuss the (...)
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  8. How to Understand Feelings of Vitality: An Approach to Their Nature, Varieties and Functions.Íngrid Vendrell-Ferran - 2021 - In Susi Ferrarello (ed.), Phenomenology of Bioethics: Technoethics and Lived Experience.
    A very basic form of experience consists in feeling energetic, vital, alive, tired, dispirited, vigorous and so on. These feelings – which I call feelings of vitality or vital feelings – constitute the main concern of this paper. My aim is to argue that these feelings exhibit a distinctive form of affectivity which cannot be explained in terms of emotions, moods, background feelings or existential feelings and to explore different paths for their conceptualization. The paper proceeds as follows. After introducing (...)
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  9. Nutzenbewertung Personalisierter Interventionen: Methodische Herausforderungen Und LösungsansätzeBenefit Assessment of Personalized Interventions: Methodological Challenges and Approaches to a Solution.Jürgen Windeler & Stefan Lange - 2013 - Ethik in der Medizin 25 (3):173-182.
    Das Ziel einer so genannten Personalisierten Medizin ist es, verfügbare oder neue Interventionen zielgerichteter einzusetzen, um so ihren Nutzen zu optimieren. Mit dieser Zielsetzung sind an eine Prüfung der Zielerreichung die gleichen Anforderungen zu stellen wie an jede andere Intervention. Der Nutzen ist durch aussagefähige Studien, typischerweise also prospektive, kontrollierte Interventionsstudien, zu belegen. Dort, wo es um den Kern personalisierter Medizin, nämlich die Verbindung von Diagnostik und Behandlung geht, ist genau diese Verbindung in Form einer statistischen Wechselwirkung zu belegen. Enrichment-Designs (...)
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  10. Randomized Controlled Trials for Diagnostic Imaging: Conceptual and Pratical Problems.Elisabetta Lalumera & Stefano Fanti - 2019 - Topoi 38 (2):395-400.
    We raise a problem of applicability of RCTs to validate nuclear diagnostic imaging tests. In spite of the wide application of PET and other similar techniques that use radiopharmaceuticals for diagnostic purposes, RCT-based evidence on their validity is sparse. We claim that this is due to a general conceptual problem that we call Prevalence of Treatment, which arises in connection with designing RCTs for testing any diagnostic procedure in the present context of medical research, and is particularly apparent in this (...)
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  11. Book Review: The Gold Standard: The Challenge of Evidence-Based Medicine and Standardization in Health Care.Martin D. Merry - 2004 - Inquiry: The Journal of Health Care Organization, Provision, and Financing 41 (2):236-237.
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  12. Mimesis and Clinical Pictures: Thinking with Plato and Broekman Through the Production and Meaning of Images of Disease.Marjolein Oele - 2018 - Medicine, Health Care and Philosophy 21 (4):507-515.
    This paper contends, following Plato and Broekman, that seeing images as images is crucial to theorizing medicine and that considering clinical pictures as images of images is a much-needed epistemic complement to the domineering view that sees clinical pictures as mirrors of disease. This does not only offer epistemic, but also ethical benefits to individual patients, especially in those cases where patients suffer from chronic, debilitating, and terminal illnesses and where medicine provides no, or limited, answers in terms of treatment, (...)
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  13. Cancer Stem Cells: Philosophy and Therapies.Lucie Laplane - 2016 - Cambridge (Massachusetts): Harvard University Press.
  14. Run the Experiment, Publish the Study, Close the Sale: Commercialized Biomedical Research.Aleta Quinn - 2016 - De Ethica 2 (3):5-21.
    Business models for biomedical research prescribe decentralization due to market selection pressures. I argue that decentralized biomedical research does not match four normative philosophical models of the role of values in science. Non-epistemic values affect the internal stages of for-profit biomedical science. Publication planning, effected by Contract Research Organizations, inhibits mechanisms for transformative criticism. The structure of contracted research precludes attribution of responsibility for foreseeable harm resulting from methodological choices. The effectiveness of business strategies leads to overrepresentation of profit values (...)
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  15. Should Phenomenological Approaches to Illness Be Wary of Naturalism?Juliette Ferry-Danini - 2019 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 73:10-18.
    In some quarters within philosophy of medicine, more particularly in the phenomenological approaches, naturalism is looked upon with suspicion. This paper argues, first, that it is necessary to distinguish between two expressions of this attitude towards naturalism: phenomenological approaches to illness disagree with naturalism regarding various theoretical claims and they disapprove of naturalism on an ethical level. Second, this paper argues that both the disagreement with and the disapproval of naturalism are to a large extent confused. It then offers some (...)
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  16. Healthcare Practice, Epistemic Injustice, and Naturalism.Ian James Kidd & Havi Carel - 2018 - Royal Institute of Philosophy Supplement 84:1-23.
    Ill persons suffer from a variety of epistemically-inflected harms and wrongs. Many of these are interpretable as specific forms of what we dub pathocentric epistemic injustices, these being ones that target and track ill persons. We sketch the general forms of pathocentric testimonial and hermeneutical injustice, each of which are pervasive within the experiences of ill persons during their encounters in healthcare contexts and the social world. What’s epistemically unjust might not be only agents, communities and institutions, but the theoretical (...)
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  17. Effects of Manual Therapy and Exercise Targeting the Hips in Patients with Low-Back Pain-A Randomized Controlled Trial.Michael Bade, Manuel Cobo-Estevez, Darren Neeley, Jeevan Pandya, Travis Gunderson & Chad Cook - 2017 - Journal of Evaluation in Clinical Practice 23 (4):734-740.
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  18. ‘One Mission Accomplished, More Important Ones Remain ’: Commentary on Every-Palmer, S., Howick, J. (2014) How Evidence-Based Medicine is Failing Due to Biased Trials and Selective Publication. J Ournal of E Valuation in C Linical P Ractice, 20 (6), 908-914. [REVIEW]Peter Wyer & Suzana Alves da Silva - 2015 - Journal of Evaluation in Clinical Practice 21 (3):518-528.
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  19. Do We Need Another Discipline in Medicine? From Epidemiology and Evidence-Based Medicine to Cognitive Medicine and Medical Thinking.Milos Jenicek - 2015 - Journal of Evaluation in Clinical Practice 21 (6):1028-1034.
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  20. What Are the Primary Influences on Treatment Decisions? How Does This Reflect on Evidence-Based Practice? Indications From the Discipline of Speech and Language Therapy.Arlene McCurtin & Amanda M. Clifford - 2015 - Journal of Evaluation in Clinical Practice 21 (6):1178-1189.
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  21. Evidence-Based Medicine and Acupuncture: Old Bias for New Perspectives in Clinical Context.Mariateresa Tassinari & Paolo Roberti di Sarsina - 2015 - Journal of Evaluation in Clinical Practice 21 (6):1035-1037.
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  22. Evidence-Based Medicine Meets Person-Centred Care: A Collaborative Perspective on the Relationship.Amy I. Price, Ben Djulbegovic, Rakesh Biswas & Pranab Chatterjee - 2015 - Journal of Evaluation in Clinical Practice 21 (6):1047-1051.
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  23. Reconciling Evidence‐Based Medicine and Patient‐Centred Care: Defining Evidence‐Based Inputs to Patient‐Centred Decisions.Robert R. Weaver - 2015 - Journal of Evaluation in Clinical Practice 21 (6):1076-1080.
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  24. The ‘Adapted ADAPTE’: An Approach to Improve Utilization of the ADAPTE Guideline Adaptation Resource Toolkit in the Alexandria Center for Evidence-Based Clinical Practice Guidelines.Yasser Sami Amer, Mahmoud Munir Elzalabany, Tarek Ismael Omar, Afaf Gaber Ibrahim & Nabil Lotfy Dowidar - 2015 - Journal of Evaluation in Clinical Practice 21 (6):1095-1106.
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  25. A ‘Reluctant’ Critical Review: ‘Manual for Evidence-Based Clinical Practice ’.Shashi S. Seshia - 2015 - Journal of Evaluation in Clinical Practice 21 (6):995-1005.
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  26. ‘All the King's Horses …’: The Problematical Fate of Born-Again Evidence-Based Medicine: Commentary on Greenhalgh, T., Snow, R., Ryan, S., Rees, S., and Salisbury, H. (2015) Six ‘Biases’ Against Patients and Carers in Evidence-Based Medicine. BioMed Centr. [REVIEW]Peter Wyer & Suzana Alves da Silva - 2015 - Journal of Evaluation in Clinical Practice 21 (6):E1-E10.
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  27. A Philosophical Argument Against Evidence-Based Policy.Rani Lill Anjum & Stephen D. Mumford - 2017 - Journal of Evaluation in Clinical Practice 23 (5):1045-1050.
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  28. Assigning Functions to Medical Technologies.Alexander Mebius - 2017 - Philosophy and Technology 30 (3):321-338.
    Modern health care relies extensively on the use of technologies for assessing and treating patients, so it is important to be certain that health care technologies perform their professed functions in an effective and safe manner. Philosophers of technology have developed methods to assign and evaluate the functions of technological products, the major elements of which are described in the ICE theory. This paper questions whether the standard of evidence advocated by the ICE theory is adequate for ascribing and assessing (...)
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  29. Metacognition, Selfexperience and the Prospect of Enhancing Selfmanagement in Schizophrenia Spectrum Disorders.Paul H. Lysaker & John T. Lysaker - 2017 - Philosophy, Psychiatry, and Psychology 24 (2):169-178.
    In general, current biomedical models of schizophrenia focus on distinguishing discrete elements that, on their own or in combination with others, might lead to some form of disability. These different and potentially autonomous aspects of the disorder that might disrupt daily activities include positive and negative symptoms as well as disturbances in neurocognitive and psychobiological processes. Such disturbances include genetic vulnerabilities that increase the risk of abnormalities in brain development, and resultant neurocognitive deficits which interfere with the ability to carry (...)
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  30. Aporia of Power: On the Crises, Science, and Internal Dynamics of the Mental Health Field.Sina Salessi - 2017 - European Journal for Philosophy of Science 7 (2):175-200.
    The myriad controversies embroiling the mental health field—heightened in the lead-up to the release of DSM-5 —merit a close analysis of the field and its epistemological underpinnings. By using DSM as a starting point, this paper develops to overview the entire mental health field. Beginning with a history of the field and its recent crises, the troubles of the past “external crisis” are compared to the contemporary “internal crisis.” In an effort to examine why crises have recurred, the internal dynamics (...)
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  31. Evidence, Discovery and Justification: The Case of Evidence-Based Medicine.Rodolfo Gaeta & Nelida Gentile - 2016 - Journal of Evaluation in Clinical Practice 22 (4):550-557.
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  32. K. Codell Carter * the Rise of Causal Concepts of Disease. Case Histories * Ashgate, 2003. * Isbn 0 7546 0678 3. [REVIEW]Donald Gillies - 2007 - British Journal for the Philosophy of Science 58 (2):365-377.
    Causality in 19th and Early 20th Century Medicine 3 A Lakatosian Approach to the History of Medicine.
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  33. Darwin Lecture Development of Controlled Trials in Preventive and Therapeutic Medicine.Richard Doll - 1991 - Journal of Biosocial Science 23 (3):365-378.
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  34. The Discursive Formation of the Body in the History of Medicine.David Michael Levin - 1990 - Journal of Medicine and Philosophy 15 (5):515.
    The principal argument of the present paper is that the human body is as much a reflective formation of multiple discourses as it is an effect of natural and environmental processes. This paper examines the implications of this argument, and suggests that recognizing the body in this light can be illuminating, not only for our conception of the body, but also for our understanding of medicine. Since medicine is itself a discursive formation, a science with both a history, and a (...)
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  35. Bioethics and the Philosophy of Medicine: A Thirty-Year Perspective.H. Tristram Engelhardt - 2006 - Journal of Medicine and Philosophy 31 (6):565-568.
  36. The Philosophy of Medicine: The Early Eighteenth Century. Engelhardt - 1982 - Philosophy of Science 49 (1):149-150.
  37. Medicine and Philosophy in Classical Antiquity: Doctors and Philosophers on Nature, Soul, Health and Disease, by Philip J. Van der Eijk. [REVIEW]Patrick Macfarlane - 2007 - Ancient Philosophy 27 (2):435-443.
  38. The Misfortunes of Moral Enhancement.Marco Antonio Azevedo - 2016 - Journal of Medicine and Philosophy 41 (5):461-479.
    In Unfit for the Future, Ingmar Persson and Julian Savulescu present a sophisticated argument in defense of the imperative of moral enhancement. They claim that without moral enhancement, the future of humanity is seriously compromised. The possibility of ultimate harm, caused by a dreadful terrorist attack or by a final unpreventable escalation of the present environmental crisis aggravated by the availability of cognitive enhancement, makes moral enhancement a top priority. It may be considered optimistic to think that our present moral (...)
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  39. Medicine and Philosophy in Classical Antiquity: Doctors and Philosophers on Nature, Soul, Health and Disease.Philip J. van der Eijk - 2005 - Cambridge University Press.
    This work brings together Philip van der Eijk's previously published essays on the close connections that existed between medicine and philosophy throughout antiquity. Medical authors such as the Hippocratic writers, Diocles, Galen, Soranus and Caelius Aurelianus elaborated on philosophical methods such as causal explanation, definition and division and applied key concepts such as the notion of nature to their understanding of the human body. Similarly, philosophers such as Plato and Aristotle were highly valued for their contributions to medicine. This interaction (...)
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  40. The Raven Paradox.John-Michael Kuczynski - 2016 - Amazon Digital Services LLC.
    "All ravens are black" is logically but not confirmationally equivalent with "all non-black things are non-ravens." But this is impossible, given that logical equivalence guarantees confirmational equivalence. In this paper, this paradox is solved.
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  41. The Oxidative Stress Theory of Disease: Levels of Evidence and Epistemological Aspects.Pietro Ghezzi, Vincent Jaquet, Fabrizio Marcucci & Harald H. H. W. Schmidt - unknown
    The theory stating that oxidative stress is at the root of several diseases is extremely popular. However, so far, no antioxidant is recommended or offered by healthcare systems neither approved as therapy by regulatory agencies that base their decisions on evidence-based medicine. This is simply because, so far, despite many preclinical and clinical studies indicating a beneficial effect of antioxidants in many disease conditions, randomised clinical trials have failed to provide the evidence of efficacy required for drug approval. In this (...)
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  42. Evolutionary Epidemiology.Daniel R. Wilson - 1992 - Acta Biotheoretica 40 (1):87-90.
    Epidemiology is a science of disease which specifies rates . Evolution is a science of life which specifies changes . ‘Evolutionary Epidemiology’ is a synthesis of these two sciences which combines the empirical power of classical methods in genetical epidemiology with the interpretive capacities of neo-darwinian evolutionary genetics. In particular, prevalence rates of genetical diseases are important data points when reformulated for the purpose of analysis in terms of their evolutionary frequencies. Traits which exceedprevalences beyond the rates of mutation or (...)
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  43. Americana A. McGehee Harvey, Science at the Bedside. Clinical Research in American Medicine 1905–1945. Baltimore: Johns Hopkins University Press, 1981. Pp. Xix + 554. £12.25/$21.85. [REVIEW]H. J. Cook - 1983 - British Journal for the History of Science 16 (3):319-319.
  44. Jeanne Daly. Evidence‐Based Medicine and the Search for a Science of Clinical Care. Xi + 275 Pp. Berkeley: University of California Press, 2005. $65. [REVIEW]Kirstin Borgerson - 2006 - Isis 97 (3):593-594.
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  45. The Epidemiology of HealthIago Galdston.John B. Blake - 1954 - Isis 45 (1):110-110.
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  46. Clinician's Guide to Evidence-Based Practices: Behavioral Health and Addictions.John C. Norcross, Thomas P. Hogan, Gerald P. Koocher & Lauren A. Maggio - 2017 - Oxford University Press USA.
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  47. Homeopathy and Evidence-Based Policy.John Worrall - 2016 - Lse Philosophy Blog.
    With the UK government considering a ban on the prescription of homeopathic remedies on the NHS, John Worrall examines the rationale for such a proposal and suggests that the decision is not as simple as it might initially seem.
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  48. Complementary and Alternative Medicine: Foundations, Ethics, and Law.Robert M. Sade - 2003 - Journal of Law, Medicine and Ethics 31 (2):183-190.
    It is doubtful that any feature of the American health care system in the last several decades has had as profound an effect on the way Americans pursue their perceived health needs as complementary and alternative medicine. Almost half of all Americans take care of some of their health care needs outside of contemporary scientific medicine. The number of visits to CAM practitioners was estimated 6 years ago to be 629 million a year, with expenditures of $27 billion a year. (...)
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  49. Avoiding Bias in Randomised Controlled Trials in Educational Research.David J. Torgerson & Carole J. Torgerson - 2003 - British Journal of Educational Studies 51 (1):36-45.
    Randomised controlled trials (RCTs) are often seen as the 'gold standard' of evaluative research. However, whilst randomisation will ensure comparable groups, trials are still vulnerable to a range of biases that can undermine their internal validity. In this paper we describe a number of common threats to the internal validity of RCTs and methods of countering them. We highlight a number of examples from randomised trials in education and health care where problems of execution and analysis of the RCT has (...)
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  50. Evidence-Based Practice in Education: The Best Medicine?Anne Pirrie - 2001 - British Journal of Educational Studies 49 (2):124-136.
    This paper explores the reasons why the notion of 'evidence-based' practice has gained prominence in educational research. The ascendancy of 'evidence-based' practice is attributed to a crisis of legitimation in educational research. The paper offers a critical exegesis of a systematic review conducted under the auspices of the Effective Practice and Organisation of Care (EPOC) subgroup of the Cochrane Collaboration.
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