Reductionism

One important aspect of biological explanation is detailed causal modeling of particular phenomena in limited experimental background conditions. Recognising this allows a new avenue for intertheoretic reduction to be seen. Reductions in biology are possible, when one fully recognises that a sufficient condition for a reduction in biology is a molecular model of 1) only the demonstrated causal parameters of a biological model and 2) only within a replicable experimental background. These intertheoretic identifications –which are ubiquitous in biology and form (...) the basis of ruthless reductions (Bickle 2003)- are criticised as merely “local” (Sullivan 2009) or “fragmentary” (Schaffner 2006). However, in an instructive case, a biological model is preserved in molecular terms, and a complex biological phenomenon has been successfully reduced. In doing this the molecular model remains valid in a broader range of background conditions and meaningfully unites disparate biological phenomena. (shrink)

In the first part of this article we will formulate postulates, which must be satisfied by a reasonable concept of emergence. The postulates will articulate conditions of adequacy for an appropriate explication of the concept of emergence. These conditions of adequacy are based primarily upon the philosophical and scientific history of the concept of emergence, in which the intended role of the concept is expressed. In the second part we will discuss and evaluate some candidates for the concept of emergence (...) in light of these conditions of adequacy. (shrink)

I will argue that Davidson's account of pure intending can be construed as a first-person-based judgement-dependent account of intention. For Davidson, pure intending to do φ is to make an all-out judgement that φing is desirable. On this anti-reductionist account, intention is treated as an irreducible state of the subject. I will draw a comparison between this account and Wright's and I will show that Davidson's account can be viewed as a non-reductionist judgement-dependent account along the lines suggested by Wright. (...) I then explain how this account can help deal with various perplexities in Davidson's later view of meaning and mental content. (shrink)

The aim of this expository paper is to give an informal overview of a plausible naturalistic case for free will. I will describe what I take to be the main naturalistically motivated challenges for free will and respond to them by presenting an indispensability argument for free will. The argument supports the reality of free will as an emergent higher-level phenomenon. I will also explain why the resulting picture of free will does not conflict with the possibility that the fundamental (...) laws of nature are deterministic, and I will address some common objections. (shrink)

Sciences of complex systems thrive on compositional theories – toolkits that allow the construction of models of a wide range of systems, each consisting of various parts put together in different ways. To be tractable, a compositional theory must make shrewd choices about the parts and properties that constitute its basic ontology. One such choice is to decompose a system into spatiotemporally discrete parts. Compositional theories in the high-level sciences follow this rule of thumb to a certain extent, but they (...) also make essential use of what I call distributed ontologies: divisions of the system into entities or states of affairs each depending on sets of fundamental-level facts that to a large extent overlap. The point is developed using the example of statistical theories in which the probabilities are ontologically distributed. (shrink)

Unity of science was once a very popular idea among both philosophers and scientists. But it has fallen out of fashion, largely because of its association with reductionism and the challenge from multiple realisation. Pluralism and the disunity of science are the new norm, and higher-level natural kinds and special science laws are considered to have an important role in scientific practice. What kind of reductionism does multiple realisability challenge? What does it take to reduce one phenomenon to another? How (...) do we determine which kinds are natural? What is the ontological basis of unity? In this Element, Tuomas Tahko examines these questions from a contemporary perspective, after a historical overview. The upshot is that there is still value in the idea of a unity of science. We can combine a modest sense of unity with pluralism and give an ontological analysis of unity in terms of natural kind monism. This title is available as Open Access on Cambridge Core. (shrink)

The causal efficacy of a material system is usually thought to be produced by the law-like actions and interactions of its constituents. Here, a specific system is constructed and explained that produces a cause that cannot be understood in this way, but instead has novel and autonomous efficacy. The construction establishes a proof-of-feasibility of strong emergence. The system works by utilizing randomness in a targeted and cyclical way, and by relying on sustained evolution by natural selection. It is not vulnerable (...) to standard arguments against strong emergence, in particular ones that assume that the physical realm is causally closed. Moreover, it does not suffer from epiphenomenalism or causal overdetermination. The system uses only standard material components and processes, and is fully consistent with naturalism. It is discussed whether the emergent cause can still be viewed as ‘material’ in the way that term is commonly understood. (shrink)

Polger and Shapiro (2016) claim that unlike human-made artifacts cases of multiple realization in naturally occurring systems are uncommon. Drawing on cases from systems biology, I argue that multiple realization in naturally occurring systems is not as uncommon as Polger and Shapiro initially thought. The relevant cases, which I draw from systems biology, involve generalizable design principles called network motifs which recur in different organisms and species and perform specific functions. I show that network motifs with entirely different underlying causal (...) structures can perform the same function of interest. The article also considers the scope problem of multiple realization. (shrink)

“Dialectic” has been a matter of growing interest in contemporary philosophy. The present article analyzes dialectical methods and positions them by reference to two paradigmatic texts of German idealism and analytic philosophy, i.e. J.G. Fichte’s Science of Knowing (1804) and J. McDowell’s Mind and World. Both dialectical approaches will be interpreted with regard to their contribution in the debate on reductionism and anti-reductionism: both Fichte and McDowell claim that philosophical positions and logical terms stand in a dualistic relationship to one (...) another, on the one hand, but are separated by a gulf, on the other. I will argue that for McDowell dialectic seems to be an alternative to one-sided reductionisms as well as to normal anti-reductionistic holism. Furthermore, for Fichte dialectic is an adequate method for describing the relationship of reductionism and anti-reductionism itself. Both see in dialectic a technique for bridging the gulf between binary opposite terms of logic as well as mutually exclusive positions, such as mind and world, subject and object, or idealism and realism. (shrink)

La description en langue naturelle est l’artefact permettant de débuter un processus d’automatisation. La tâche principale de l’ingénieur du logiciel, c’est de combler le clivage entre langue naturelle et langue de la machine. Après avoir présenté quelques ontologies définies pour les processus d’automatisation, quelques pour et quelques contre l’emploi d’ontologies dans le génie logiciel sont présentées. Des indications pour dépasser cette simple opposition sont ensuite décrites. Des évaluations sur le réductionnisme dans les ontologies en ce qui concerne les possibles interactions (...) entre humains, machines et réalité muette terminent la présentation. (shrink)

This article examines the multiple realizability thesis within a causal framework. The beginnings of this framework are found in Elliott Sober’s “Multiple Realizability Argument against Reduction,”...

Último sermón de la iglesia del naturalismo fundamentalista por el pastor Hofstadter. Al igual que su mucho más famoso (o infame por sus incesantemente errores filosóficos) trabajo Godel, Escher, Bach, tiene una plausibilidad superficial, pero si se entiende que se trata de un científico rampante que mezcla problemas científicos reales con los filosóficos (es decir, el sólo los problemas reales son los juegos de idiomas que debemos jugar) entonces casi todo su interés desaparece. Proporciono un marco para el análisis basado (...) en la psicología evolutiva y el trabajo de Wittgenstein (ya actualizado en mis escritos más recientes). Aquellos que deseen un marco completo hasta la fecha para el comportamiento humano de la moderna dos sistemas punto de vista puede consultar mi libros Talking Monkeys 3ª ed (2019), Estructura Logica de Filosofia, Psicología, Mente y Lenguaje en Ludwig Wittgenstein y John Searle 2ª ed (2019), Suicidio pela Democracia 4ª ed (2019), La Estructura Logica del Comportamiento Humano (2019), The Logical Structure de la Conciencia (2019, Comprender las Conexiones entre Ciencia, Filosofía, Psicología, Religión, Política y Economía, Historia y Literatura (2019), Delirios Utópicos Suicidas en el siglo 21 5ª ed (2019), Observaciones sobre Imposibilidad, Incompletitud, Paraconsistencia, Indecidibilidad, Aleatoriedad, Computabilidad, Paradoja e Incertidumbre en Chaitin, Wittgenstein, Hofstadter, Wolpert, Doria, da Costa, Godel, Searle, Rodych Berto, Floyd, Moyal-Sharrock y Yanofsky(2019) y otros. "Podría ser justamente preguntado qué importancia tiene la prueba de Gödel para nuestro trabajo. Para un pedazo de matemáticas no puede resolver problemas del tipo que nos molesten. --La respuesta es que la situación, en la que tal prueba nos trae, es de interés para nosotros. ' ¿Qué vamos a decir ahora? ' --Ese es nuestro tema. Sin embargo, extraña que suene, mi tarea en lo que concierne a la prueba de Gödel parece meramente consistir en aclarar lo que tal proposición como: "Supongamos que esto se puede demostrar" significa en matemáticas. " Wittgenstein "Comentarios sobre los fundamentos de las matemáticas" p337 (1956) (escrito en 1937). "Mis teoremas sólo muestran que la mecanización de las matemáticas, es decir, la eliminación de la mente y de las entidades abstractas, es imposible, si uno quiere tener una base satisfactoria y un sistema de matemáticas. No he probado que haya preguntas matemáticas que sean indescifrables para la mente humana, pero sólo que no hay máquina (o formalismo ciego) que pueda decidir todas las preguntas de la teoría numérica, (incluso de un tipo muy especial) .... No es la estructura misma de los sistemas deductivos que está siendo amenazado con un descompostura, sino sólo una cierta interpretación de la misma, es decir, su interpretación como un formalismo ciego. " Gödel "Obras Recogidas" VOL 5, p 176-177. (2003) "Toda inferencia tiene lugar a priori. Los acontecimientos del futuro no pueden deducirse de los del presente. La superstición es la creencia en el nexo causal. La libertad de la voluntad consiste en el hecho de que las acciones futuras no se pueden conocer ahora. Sólo podíamos conocerlas si la causalidad fuera una necesidad interna, como la de la deducción lógica. --La conexión del conocimiento y lo que se conoce es la necesidad lógica. ("A sabe que p es el caso" no tiene sentido si p es una tautología.) Si por el hecho de que una proposición es obvia para nosotros, no sigue que es verdad, entonces la evidencia no es ninguna justificación para creer en su verdad. " TLP 5,133--5,1363 . (shrink)

"Люди говорят снова и снова, что философия на самом деле не прогресс, что мы по-прежнему заняты теми же философскими проблемами, что и греки. Но люди, которые говорят это, не понимают, почему это должно быть так. Это потому, что наш язык остался прежним и продолжает соблазнять нас задавать те же вопросы. До тех пор, пока по-прежнему существует глагол, который выглядит так, как будто он функционирует так же, как «есть и пить», до тех пор, пока у нас есть прилагательные «идентично», «правда» ( (...) « » » » » » » » » » возможно, до тех пор, как мы продолжаем говорить о реке времени, просторы пространства и т.д., и т.д., люди будут держать спотыкаясь над темже загадочные трудности и найти себя глядя на то, что никакое объяснение, кажется, способны очистки. И более того, это удовлетворяет стремление к трансцендентной, потому что, поскольку люди думают, что они могут видеть ‘"пределы человеческого понимания", они считают, конечно, тони могут видеть за этим. Эта цитата из Людвиг Витгенштейн, который пересмотрел философию около 70 лет назад (но большинство людей до сих пор не выяснить это). Деннетт, хотя он был философом в течение 40 лет, является одним из них. Любопытно также, что и он, и его главный антагонист Джон Сирл учились у знаменитых Витгенштейнов (Сирл с Джоном Остином, Деннет с Гилбертом Райлом), но Сирл более или менее получил точку, а Деннет т , (хотя это растяжение вещей, чтобы назвать Сирл или Райл Витгенштейнов). Деннетт является жесткий детерминант (хотя он пытается проникнуть реальность в задней двери), и, возможно, это связано с Райл, чья знаменитая книга "Концепция разума" (1949) продолжает быть перепечатаны. Эта книга проделала большую работу по изгнанию призрака, но он покинул машину. Деннетт любит делать ошибки Витгенштейна, Райл (и многие другие с тех пор) разоблачили в деталях. Наше использование слов сознание, выбор, свобода, намерение, частицы, мышление, определяет, волна, причина, произошло, событие (и так далее бесконечно) редко источником путаницы, но как только мы оставляем нормальную жизнь и введите философию (и любое обсуждение отделены от среды, в которой язык развивался-т.е., точный контекст, в котором слова имели смысл)хаос царит. Как и большинству,, Деннетне не хватает когерентной структуры - которую Сирл назвал логической структурой рациональности. Я расширил на этом значительно, так как я написал этот обзор, и мои последние статьи показывают подробно, что случилось с подходом Деннетк к философии, который можно было бы назвать Scientism на стероидах. Позвольте мне закончить с другой цитатой из Витгенштейна - "Амбиции является смерть мысли. Те, кто желает всеобъемлющего до современных рамок для человеческого поведения из современных двух systEms зрения могут проконсультироваться с моей книгой"Логическая структура философии, психологии, Минd иязык в Людвиг Витгенштейн и Джон Сирл" второй ред (2019). Те, кто заинтересован в более моих сочинений могут увидеть "Говоря обезьян - Философия, психология, наука, религия и политика на обреченной планете - Статьи и обзоры 2006-2019 3-й ed (2019) и suicidal утопических заблуждений в 21-мst веке 4-й ed (2019) th и другие. (shrink)

Biochemical kinds such as proteins pose interesting problems for philosophers of science, as they can be studied from the points of view of both biology and chemistry. The relationship between the biological functions of biochemical kinds and the microstructures that they are related to is the key question. This leads us to a more general discussion about ontological reductionism, microstructuralism, and multiple realization at the biology-chemistry interface. On the face of it, biochemical kinds seem to pose a challenge for ontological (...) reductionism and hence motivate a dual theory of chemical and biological kinds, a type of pluralism about natural kinds. But it will be argued that the challenge, which is based on multiple realization, can be addressed. The upshot is that there are reasonable prospects for ontological reductionism about biochemical kinds, which corroborates natural kind monism. (shrink)

Reductionists say things like: all mental properties are physical properties; all normative properties are natural properties. I argue that the only way to resist reductionism is to deny that causation is difference making (thus making the epistemology of causation a mystery) or to deny that properties are individuated by their causal powers (thus making properties a mystery). That is to say, unless one is happy to deny supervenience, or to trivialize the debate over reductionism. To show this, I argue that (...) if properties are individuated by their causal powers then, surprisingly, properties are individuated by necessary co-exemplification. (shrink)

Each thing is fundamental. Not only is no thing any more or less real than any other, but no thing is prior to another in any robust ontological sense. Thus, no thing can explain the very existence of another, nor account for how another is what it is. I reach this surprising conclusion by undermining two important positions in contemporary metaphysics: hylomorphism and hierarchical views employing so-called building relations, such as grounding. The paper has three main parts. First, I observe (...) hylomorphism is alleged by its proponents to solve various philosophical problems. However, I demonstrate, in light of a compelling account of explanation, that these problems are actually demands to explain what cannot be but inexplicable. Second, I show how my argument against hylomorphism illuminates an account of the essence of a thing, thereby providing insight into what it is to exist. This indicates what a thing, in the most general sense, must be and a correlative account of the structure in reality. Third, I argue that this account of structure is incompatible not only with hylomorphism, but also with any hierarchical view of reality. Although hylomorphism and the latter views are quite different, representing distinct philosophical traditions, I maintain they share untenable accounts of structure and fundamentality and so should be rejected on the same grounds. (shrink)

Universitäten weisen als institutioneller Inbegriff von Wissenschaft eine immense Fächervielfalt auf. Doch was hält diese Vielfalt der Wissenschaften zusammen, und was sind deren jeweiligen Besonderheiten? Ist es überhaupt sinnvoll, solch unterschiedliche Forschungsbereiche wie zum Beispiel die Koptologie und die Materialphysik nach ähnlichen Standards zu bewerten und zu vergleichen? Ist solch eine Vielfalt notwendig für den Erkenntnisfortschritt oder eher ein Hemmnis, das es zu überwinden gilt? Wie hängen die Theorien, Methoden und Gegenstandsbereiche der verschiedenen Disziplinen miteinander zusammen – haben die Disziplinen (...) einen je eigenen Zugriff auf verschiedene Aspekte der Wirklichkeit, oder lassen sich die Theorien und Erklärungen einiger Disziplinen auf die anderer zurückführen? Fragen dieser Art werden in diesem Buch aus der Perspektive verschiedener Disziplinen betrachtet. (shrink)

Psychiatry uncomfortably spans biological, psychological, and social perspectives on mental illness. As a branch of medicine, psychiatry is under pressure to conform to a biomedical model, according to which diseases are characterized primarily in biological terms. But psychiatry also draws on the psychotherapeutic tradition, which explains mental distress in terms of life experience and social influences.These approaches ought to complement each other, but historically this has not happened. With no theory creating global, systematic links between the two approaches, psychiatry is (...) divided... (shrink)

Reduction between theories in physics is often approached as an a priori relation in the sense that reduction is often taken to depend only on a comparison of the mathematical structures of two theories. I argue that such approaches fail to capture one crucial sense of “reduction,” whereby one theory encompasses the set of real behaviors that are well-modeled by the other. Reduction in this sense depends not only on the mathematical structures of the theories, but also on empirical facts (...) about where our theories succeed at describing real systems, and is therefore an a posteriori relation. (shrink)

This thesis investigates the epistemological and metaphysical relations between chemistry and quantum mechanics. These relations are examined with respect to how chemistry and quantum mechanics each describe a single inert molecule. A review of how these relations are understood in the literature shows that there is a proliferation of positions which focus on how chemistry is separate from quantum mechanics. This proliferation is accompanied by a tendency within the philosophy of chemistry community to connect the legitimacy of the field with (...) the autonomy of chemistry. First, it is argued that this connection should not be made. Secondly, it is argued that chemistry and quantum mechanics are unified in accordance with Harold Kincaid’s model of non-reductive unity because the two theories exhibit particular epistemic and metaphysical interconnections. Thirdly, a metaphysical account is examined which is incompatible with Kincaid’s model of unity; namely strong emergence as understood by Robin Hendry. According to Hendry, the structure of a single inert molecule strongly emerges from its quantum mechanical entities in the sense that there is downward causation. However, Hendry’s defense of this account faces certain problems. Moreover, the putative empirical evidence for his understanding of strong emergence can be explained without invoking strong emergence. This is shown by considering how quantum mechanics assumes an idealized understanding of a molecule’s stability and structure. In the light of the philosophical literature on idealizations, this idealization can be interpreted in two different ways, both of which explain why quantum mechanics describes the structure of a single molecule the way it does, without assuming strong emergence in Hendry’s sense. Each interpretation has philosophical implications regarding the nature of chemical properties, and the relation of chemistry and quantum mechanics. These implications are consistent with Kincaid’s model of unity and thus further support chemistry’s unity with quantum mechanics (as per Kincaid). (shrink)

Es mi afirmación que la tabla de intencionalidad (racionalidad, mente, pensamiento, lenguaje, personalidad, etc.) que presenta prominentemente aquí describe más o menos con precisión, o al menos sirve como heurística para, cómo pensamos y nos comportamos, y por lo tanto no abarca simplemente filosofía y psicología, sino todo lo demás (historia, literatura, matemáticas, política, etc.). Tenga en cuenta especialmente que la intencionalidad y racionalidad como yo (junto con Searle, Wittgenstein y otros) lo veo, incluye tanto el Sistema Linguístico deliberativo consciente (...) 2 como las acciones o reflejos inconscientes automatizados del Sistema 1 automatizado. -/- Proporciono una encuesta crítica de algunos de los principales hallazgos de dos de los estudiantes más eminentes del comportamiento de los tiempos modernos, Ludwig Wittgenstein y John Searle, sobre la estructura lógica de la intencionalidad (mente, lenguaje, comportamiento), tomando como punto de partida El descubrimiento fundamental de Wittgenstein -que todos los problemas verdaderamente "filosóficos" son los mismos —confusiones sobre cómo usar el lenguaje en un contexto particular, y por lo tanto todas las soluciones son iguales— mirando cómo se puede utilizar el lenguaje en el contexto en cuestión para que su verdad condiciones (Condiciones de Satisfacción o COS) son claras. El problema básico es que se puede decir cualquier cosa, pero no se puede significar (indicar COS claro para) cualquier expresión arbitraria y significado sólo es posible en un contexto muy específico. Analizo varios escritos por y sobre ellos desde la perspectiva moderna de los dos sistemas de pensamiento (popularizados como 'pensar rápido, pensar lento'), empleando una nueva tabla de intencionalidad y nueva nomenclatura de sistemas duales. Demuestro que esta es una heurística poderosa para describir el comportamiento. -/- Por lo tanto, todo comportamiento está íntimamente conectado si uno toma el punto de vista correcto. La Ilusión Fenomenológica (olvido a nuestro Sistema automatizado 1) es universal y se extiende no sólo a lo largo de la filosofía, sino a lo largo de la vida. Estoy seguro de que Chomsky, Obama, Zuckerberg y el Papa serían incrédulos si se les dijera que sufren del mismo problema que Hegel, Husserl y Heidegger, (o que difieren sólo en grado de los adictos a las drogas y el sexo en estar motivados por la estimulación de su cortices frontales por la entrega de dopamina (y más de 100 otros productos químicos) a través del tegmentum ventral y el núcleo accumbens), pero es claramente cierto. Mientras que los fenomenólogos sólo desperdiciaron mucho el tiempo de la gente, están desperdiciando la tierra y el futuro de sus descendientes. -/- . (shrink)

Intertheoretic relations are an important topic in the philosophy of science. However, since their classical discussion by Ernest Nagel, such relations have mostly been restricted to relations between pairs of theories in the natural sciences. This paper presents a case study of a new type of intertheoretic relation that is inspired by Montague’s analysis of the linguistic syntax-semantics relation. The paper develops a simple model of this relation. To motivate the adoption of our new model, we show that this model (...) extends the scope of application of the Nagelian models and that it shares the epistemological advantages of the Nagelian model. The latter is achieved in a Bayesian framework. (shrink)

Ethical reductionism is the best version of naturalistic moral realism. Reductionists regard moral properties as identical to properties appearing in successful scientific theories. Nonreductionists, including many of the Cornell Realists, argue that moral properties instead supervene on scientific properties without identity. I respond to two arguments for nonreductionism. First, nonreductionists argue that the multiple realizability of moral properties defeats reductionism. Multiple realizability can be addressed in ethics by identifying moral properties uniquely or disjunctively with properties of the special sciences. Second, (...) nonreductionists argue that irreducible moral properties explain empirical phenomena, just as irreducible special-science properties do. But since irreducible moral properties don't successfully explain additional regularities, they run the risk of being pseudoscientific properties. Reductionism has all the benefits of nonreductionism, while also being more secure against anti-realist objections because of its ontological simplicity. (shrink)

We argue for the mind’s independence from the body. We do so by making several moves. First, we analyze two popular kinds of reasons which have swayed many to adopt the independence of the mind from the body. Second, we advance an argument from the ontology of intentionality against the identity thesis, according to which the mind is identical to the brain. We try to show how intentionality is not reducible to or identical to the physical. Lastly, we argue that, (...) contrary to what many materialists contend, the concept of a mind, understood as an immaterial substance, existing independently of the body is both coherent and empirically evidenced. (shrink)

Some explanations in social science, psychology and biology belong to a higher level than other explanations. And higher explanations possess the virtue of abstracting away from the details of lower explanations, many philosophers argue. As a result, these higher explanations are irreplaceable. And this suggests that there are genuine higher laws or patterns involving social, psychological and biological states. I show that this ‘abstractness argument’ is really an argument schema, not a single argument. This is because the argument uses the (...) ‘is lower than’ relation, and this relation admits of different readings. I then suggest four rigorous definitions of the ‘is lower than’ relation, and show that the abstractness argument’s prospects are much brighter for some of these definitions than for others. To show this, I evaluate the so-called ‘disjunctive threat’ to the abstractness argument. (shrink)

Courtesy of its free energy formulation, the hierarchical predictive processing theory of the brain (PTB) is often claimed to be a grand unifying theory. To test this claim, we examine a central case: activity of mesocorticolimbic dopaminergic (DA) systems. After reviewing the three most prominent hypotheses of DA activity—the anhedonia, incentive salience, and reward prediction error hypotheses—we conclude that the evidence currently vindicates explanatory pluralism. This vindication implies that the grand unifying claims of advocates of PTB are unwarranted. More generally, (...) we suggest that the form of scientific progress in the cognitive sciences is unlikely to be a single overarching grand unifying theory. (shrink)

The problem with reductionism in biology is not the reduction, but the implicit attitude of determinism that usually accompanies it. Methodological reductionism is supported by deterministic beliefs, but making such a connection is problematic when it is based on an idea of determinism as fixed predictability. Conflating determinism with predictability gives rise to inaccurate models that overlook the dynamic complexity of our world, as well as ignore our epistemic limitations when we try to model it. Furthermore, the assumption of a (...) strictly deterministic framework is unnecessarily hindering to biology. By removing the dogma of determinism, biological methods, including reductive methods, can be expanded to include stochastic models and probabilistic interpretations. Thus, the dogma of reductionism can be saved once its ties with determinism are severed. In this paper, I analyze two problems that have faced molecular biology for the last 50 years—protein folding and cancer. Both cases demonstrate the long influence of reductionism and determinism on molecular biology, as well as how abandoning determinism has opened the door to more probabilistic and unconstrained reductive methods in biology. (shrink)

In recent years, several authors advocated neuroscience imperialism, an instance of scientific imperialism whereby neuroscience methods and findings are systematically applied to model and explain phenomena investigated by other disciplines. Calls for neuroscience imperialism target a wide range of disciplines, including psychology, economics, and philosophy. To date, however, neuroscience imperialism has not received detailed attention by philosophers, and the debate concerning its identification and normative assessment is relatively underdeveloped. In this paper, I aim to remedy this situation by making some (...) conceptual distinctions about neuroscience imperialism and by providing a normative assessment of prominent calls in its favour. I shall articulate and defend two interrelated claims that, I argue, undermine prominent calls for neuroscience imperialism. First, the proponents of neuroscience imperialism significantly overstate the evidential and explanatory relevance of neuroscience methods and findings for the disciplines they target. And second, prominent calls for neuroscience imperialism point to an untenable reductionist position, which rests on unsupported empirical and normative presuppositions. To substantiate these two claims, I shall draw on two sets of influential calls for neuroscience imperialism, which respectively target the economic modelling of choice and entrenched philosophical conceptions of free agency. (shrink)

Systems biologists often distance themselves from reductionist approaches and formulate their aim as understanding living systems “as a whole.” Yet, it is often unclear what kind of reductionism they have in mind, and in what sense their methodologies would offer a superior approach. To address these questions, we distinguish between two types of reductionism which we call “modular reductionism” and “bottom-up reductionism.” Much knowledge in molecular biology has been gained by decomposing living systems into functional modules or through detailed studies (...) of molecular processes. We ask whether systems biology provides novel ways to recompose these findings in the context of the system as a whole via computational simulations. As an example of computational integration of modules, we analyze the first whole-cell model of the bacterium M. genitalium. Secondly, we examine the attempt to recompose processes across different spatial scales via multi-scale cardiac models. Although these models rely on a number of idealizations and simplifying assumptions as well, we argue that they provide insight into the limitations of reductionist approaches. Whole-cell models can be used to discover properties arising at the interfaces of dynamically coupled processes within a biological system, thereby making more apparent what is lost through decomposition. Similarly, multi-scale modeling highlights the relevance of macroscale parameters and models and challenges the view that living systems can be understood “bottom-up.” Specifically, we point out that system-level properties constrain lower-scale processes. Thus, large-scale modeling reveals how living systems at the same time are more and less than the sum of the parts. (shrink)

Is an epistemological reduction strictly possible? Scientific methodology claims that a boundary separating the system from the “extra-system” can be defi ned. However, no system defi nes its own limits: rather, every system needs extra-systemic presuppositions that are defi ned from outside the system. In this article, we show how various areas of knowledge presuppose the presence of an extra-systemic reality that provides meaning: to know any system, knowledge of the “extra-system” is also necessary.

In this paper, I propose a general taxonomy of different forms of eliminativism. In order to do so, I begin by exploring eliminativism from a broad perspective, providing a comparative picture of eliminativist projects in different domains. This exploration shows that eliminativism is a label used for a family of related types of eliminativist arguments and claims. The proposed taxonomy is an attempt to systematise those arguments and claims.

In their Every Thing Must Go, Ladyman and Ross defend a novel version of Neo- Russellian metaphysics of causation, which falls into three claims: (1) there are no fundamental physical causal facts (orthodox Russellian claim), (2) there are higher-level causal facts of the special sciences, and (3) higher-level causal facts are explanatorily emergent. While accepting claims (1) and (2), I attack claim (3). Ladyman and Ross argue that higher-level causal facts are explanatorily emergent, because (a) certain aspects of these higher-level (...) facts (their universality) can be captured by renormalization group (RG) explanations, and (b) RG explanations are not reductive explanations. However, I argue that RG explanation should be understood as reductive explanations. This result undermines Ladyman and Ross’s RG-based argument for the explanatory emergence of higher-level causal facts. (shrink)

Flat Physicalism is a theory of through and through type reductive physicalism, understood in light of recent results in the conceptual foundations of physics. In Flat Physicalism, as in physics, so-called "high level" concepts and laws are nothing but partial descriptions of the complete states of affairs of the universe. "Flat physicalism" generalizes this idea, to form a reductive picture in which there is no room for levels, neither explanatory nor ontological. The paper explains how phenomena that seem to be (...) cases of multiple realization of special sciences kinds by physical kinds are fully explains in a reductive physicalist way. Finally, the paper exemplifies the fruitfulness of this reductive approach by showing how it can account even for a case of high-level anomaly in a deterministic universe (for example anomaly of the mental, should this turn our to be a fact about the world) - a result that may be called Anomalous Physicalism. (shrink)

Statistical mechanics is a strange theory. Its aims are debated, its methods are contested, its main claims have never been fully proven, and their very truth is challenged, yet at the same time, it enjoys huge empirical success and gives us the feeling that we understand important phenomena. What is this weird theory, exactly? Statistical mechanics is the name of the ongoing attempt to apply mechanics, together with some auxiliary hypotheses, to explain and predict certain phenomena, above all those described (...) by thermodynamics. This paper shows what parts of this objective can be achieved with mechanics by itself. It thus clarifies what roles remain for the auxiliary assumptions that are needed to achieve the rest of the desiderata. Those auxiliary hypotheses are described in another paper in this journal, Foundations of statistical mechanics: The auxiliary hypotheses. (shrink)

Science as we know it is “dappled”. Its picture of the world is a mosaic in which different aspects of the world, different systems, are represented by narrow-scope theories or models that are largely disconnected from one another. The best explanation for this disunity in our representation of the world, Nancy Cartwright has proposed, is a disunity in the world itself: rather than being governed by a small set of strict fundamental laws, events unfold according to a patchwork of principles (...) covering different kinds of systems or segments of reality, each with something less than full omnipotence and with the possibility of anomic indeterminism at the boundaries. This paper attempts to undercut Cartwright’s argument for a dappled world by showing that the motley nature of science, both now and even at the completion of empirical inquiry, can equally well be explained by proponents of the “fundamentalist” view that the universe’s initial conditions and fundamental physical laws determine everything that ever happens. (shrink)

Review of Carl Gillett's "Reduction and Emergence in Science and Philosophy.".

In this paper I argue that non-reductive physicalism (NRP) continues to rely on the ontological aspect of the layer cake model of the world (LCM). NRP is a post-unity account of the relationship between phenomena in the world in the sense that it has been developed in response to the perceived failure of the unity of science thesis. The LCM constitutes a framework for the organisation of phenomena in the world. It articulates the idea that phenomena in the world are (...) organised into levels. Specifically, that phenomena are layered into distinct, hierarchical levels of organisation. Historically, the unity of science thesis and the LCM have been intertwined; the LCM being the framework within which a unity of science might be possible. My argument will demonstrate that, despite a move away from unity of science positions, the LCM persists in post-unity accounts. In order to argue for this thesis, I present a close analysis of Oppenheim & Putnam’s classic presentation of the LCM; picking out the principle of hierarchic compositionality which, I argue, captures the ontological aspect of the LCM. I then demonstrate how NRP continues to rely upon the principle and, as a result, continues to support the ontological aspect of the LCM. This result is significant. It shows that whilst the rejection of the reductionist aspect of the thesis has served as the basis for post-unity positions these positions do not engage directly with the framework within which reduction might be facilitated – the LCM. Furthermore, it demonstrates that pluralist or disunity accounts of the relationship between phenomena in the world will also have to engage directly with the framework of the LCM in order to avoid being merely anti-reductionist. (shrink)

Some explanations are relatively abstract: they abstract away from the idiosyncratic or messy details of the case in hand. The received wisdom in philosophy is that this is a virtue for any explanation to possess. I argue that the apparent consensus on this point is illusory. When philosophers make this claim, they differ on which of four alternative varieties of abstractness they have in mind. What’s more, for each variety of abstractness there are several alternative reasons to think that the (...) variety of abstractness in question is a virtue. I identify the most promising reasons, and dismiss some others. The paper concludes by relating this discussion to the idea that explanations in biology, psychology and social science cannot be replaced by relatively micro explanations without loss of understanding. (shrink)

Robert B. Brandom’s From Empiricism to Expressivism ranges widely over fundamental issues in metaphysics, with occasional forays into epistemology as well. The centerpiece is what Brandom calls ‘the Kant-Sellars thesis about modality’. This is ‘[t]he claim that in being able to use ordinary empirical descriptive vocabulary, one already knows how to do everything that one needs to know how to do, in principle, to use alethic modal vocabulary – in particular subjunctive conditionals’. Despite claiming descent from Sellars, Brandom defends here (...) a version of modal realism and tries hard to limit Sellarsian nominalism, all in the service of elaborating Brandom’s own version of pragmatism. The range of issues Brandom addresses defies adequate consideration in a critical notice, so I confine myself here to a single issue: What is.. (shrink)

Physicalism is the thesis that everything is physical. But what does it mean to say that everything is physical? Daniel Stoljar has recently argued that no account of the physical is available which allows for a formulation of physicalism that is both possibly true and deserving of the name. As against this claim, I argue that a version of the via negativa—roughly, the view that the physical is to be characterised in terms of the nonmental—provides just such an account.

Grand debates over reduction and emergence are playing out across the sciences, but these debates have reached a stalemate, with both sides declaring victory on empirical grounds. In this book, Carl Gillett provides new theoretical frameworks with which to understand these debates, illuminating both the novel positions of scientific reductionists and emergentists and the recent empirical advances that drive these new views. Gillett also highlights the flaws in existing philosophical frameworks and reorients the discussion to reflect the new scientific advances (...) and issues, including the nature of 'parts' and 'wholes', the character of aggregation, and thus the continuity of nature itself. Most importantly, Gillett shows how disputes about concrete scientific cases are empirically resolvable and hence how we can break the scientific stalemate. Including a detailed glossary of key terms, this volume will be valuable for researchers and advanced students of the philosophy of science and metaphysics, and scientific researchers working in the area. (shrink)

Reduction and reductionism have been central philosophical topics in analytic philosophy of science for more than six decades. Together they encompass a diversity of issues from metaphysics and epistemology. This article provides an introduction to the topic that illuminates how contemporary epistemological discussions took their shape historically and limns the contours of concrete cases of reduction in specific natural sciences. The unity of science and the impulse to accomplish compositional reduction in accord with a layer-cake vision of the sciences, the (...) seminal contributions of Ernest Nagel on theory reduction and how they strongly conditioned subsequent philosophical discussions, and the detailed issues pertaining to different accounts of reduction that arise in both physical and biological science (e.g., limit-case and part-whole reduction in physics, the difference-making principle in genetics, and mechanisms in molecular biology) are explored. The conclusion argues that the epistemological heterogeneity and patchwork organization of the natural sciences encourages a pluralist stance about reduction. (shrink)

Reduction and reductionism have been central philosophical topics in analytic philosophy of science for more than six decades. Together they encompass a diversity of issues from metaphysics and epistemology. This article provides an introduction to the topic that illuminates how contemporary epistemological discussions took their shape historically and limns the contours of concrete cases of reduction in specific natural sciences. The unity of science and the impulse to accomplish compositional reduction in accord with a layer-cake vision of the sciences, the (...) seminal contributions of Ernest Nagel on theory reduction and how they strongly conditioned subsequent philosophical discussions, and the detailed issues pertaining to different accounts of reduction that arise in both physical and biological science (e.g., limit-case and part-whole reduction in physics, the difference-making principle in genetics, and mechanisms in molecular biology) are explored. The conclusion argues that the epistemological heterogeneity and patchwork organization of the natural sciences encourages a pluralist stance about reduction. (shrink)

In the seminal essay, "On the unreasonable effectiveness of mathematics in the physical sciences," physicist Eugene Wigner poses a fundamental philosophical question concerning the relationship between a physical system and our capacity to model its behavior with the symbolic language of mathematics. In this essay, I examine an ambitious 16th and 17th-century intellectual agenda from the perspective of Wigner's question, namely, what historian Paolo Rossi calls "the quest to create a universal language." While many elite thinkers pursued related ideas, the (...) most inspiring and forceful was Gottfried Leibniz's effort to create a "universal calculus," a pictorial language which would transparently represent the entirety of human knowledge, as well as an associated symbolic calculus with which to model the behavior of physical systems and derive new truths. I suggest that a deeper understanding of why the efforts of Leibniz and others failed could shed light on Wigner's original question. I argue that the notion of reductionism is crucial to characterizing the failure of Leibniz's agenda, but that a decisive argument for the why the promises of this effort did not materialize is still lacking. (shrink)